Journal of Foot and Ankle Research最新文献

{"title":"Clinical Outcomes of Custom Foot Orthoses in Progressive Collapsing Foot Deformity: A Retrospective Cohort Analysis.","authors":"Kelly Robb, Michael Ryan, Gabriel Moisan","doi":"10.1002/jfa2.70153","DOIUrl":"10.1002/jfa2.70153","url":null,"abstract":"<p><strong>Background: </strong>Progressive collapsing foot deformity (PCFD) is a painful and function-limiting condition most commonly affecting middle-aged and older adults. Although custom foot orthoses (CFOs) are routinely prescribed as a conservative intervention, evidence from large clinical cohorts remains limited. This study aimed to characterise patients with PCFD seeking orthotic care, examine demographic factors associated with pain improvement, evaluate clinical and self-reported outcomes following CFO use, and explore potential interaction effects of CFOs on clinical improvement across sex.</p><p><strong>Methods: </strong>A retrospective analysis of clinical records between January 1, 2016 and May 31, 2025 extracted 130,365 appointments across 25 Canadian pedorthic clinics, further extrapolated into 669 PCFD encounters and 12,621 asymptomatic controls. Each assessment included pain ratings, Foot Posture Index (FPI), functional tests, gait analysis, and follow-up surveys on CFOs wear time, comfort, and recovery.</p><p><strong>Results: </strong>Results identified that PCFD was more prevalent in females and older adults. Unilateral PCFD limbs demonstrated significantly higher FPI scores (flatter feet) than contralateral healthy limbs. Both sexes demonstrated significant pain reduction following CFOs use, with females reporting higher pain at baseline and follow-up. Mean pain decreased from 6.52 ± 2.56 at assessment to 3.69 ± 2.52 at follow-up (p < 0.0001). Eighty percent of patients reported symptoms improvement, and 56% wore orthoses for more than 6 hours per day. Comfort was positively associated with both wear time and magnitude of pain reduction.</p><p><strong>Conclusions: </strong>CFOs were associated with meaningful pain reduction, improved function, and high patient-reported benefit in individuals with PCFD. These findings support CFOs as a cost-effective conservative intervention and provide essential data to inform the design of a future randomised controlled trial evaluating their clinical efficacy.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 2","pages":"e70153"},"PeriodicalIF":2.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13111764/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147787032","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advancing Conservative Treatment of Knee Osteoarthritis: 3D-Printed Shoe Soles for Passive Toe-Out Gait Modification.","authors":"Ziang Jiang, Paciane Bo Studer, Matthias Zäh, Christian Kryenbühl, Stephan Reichenbach, William R Taylor, Qiang Zhang","doi":"10.1002/jfa2.70174","DOIUrl":"10.1002/jfa2.70174","url":null,"abstract":"<p><strong>Introduction: </strong>To evaluate whether a 3D-printed shoe sole can passively replicate toe-out gait biomechanics and reduce the knee adduction moment (KAM) and knee adduction angular impulse (KAAI), addressing limitations of traditional gait retraining.</p><p><strong>Methods: </strong>Custom shoe soles were 3D-printed using gyroid infill structures to create a rotational hind-sole and a variable stiffness fore-sole ('RVS' shoes). Twenty-one healthy adults completed three baseline gait trials in control shoes, followed by randomised biofeedback-based gait retraining at toe-out angles of 5°, 10° and 15°. After each retraining session, motion capture was used during overground walking. Participants then walked wearing RVS shoes for three trials. Gait biomechanics were analysed using repeated measures ANOVA and multiple linear regression.</p><p><strong>Results: </strong>Compared to baseline, KAM's second peak was significantly reduced after toe-out retraining: 5° (13.6%, p = 0.002), 10° (20.2%, p < 0.001) and 15° (31.7%, p < 0.001). RVS shoes alone reduced it by 16.3% (p < 0.001), and KAAI by 8.6% (p < 0.001)-a reduction not achieved by retraining. Regression analysis showed that changes in KAM were strongly predicted (95%) by knee centre-of-pressure offset and mediolateral ground reaction force.</p><p><strong>Conclusion: </strong>3D-printed RVS shoes passively replicated or exceeded the biomechanical effects of active toe-out gait retraining, offering a promising, low-effort intervention for managing knee osteoarthritis.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 2","pages":"e70174"},"PeriodicalIF":2.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13286866/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148302930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Mental Health Predictors of Dynamic Balance in Individuals With Chronic Ankle Instability.","authors":"Abbis Jaffri","doi":"10.1002/jfa2.70152","DOIUrl":"10.1002/jfa2.70152","url":null,"abstract":"<p><strong>Background: </strong>Chronic ankle instability (CAI) is linked to impaired dynamic balance and psychological deficits, potentially hindering optimal rehabilitation outcomes. However, the impact of psychological deficits on dynamic balance has not been explored before. Therefore, the aim of this study is to determine whether mental health factors predict dynamic balance performance in individuals with CAI using the Star Excursion Balance Test (SEBT).</p><p><strong>Methods: </strong>This is a cross-sectional observational study performed in a university setting. Forty individuals with CAI (17 men, 23 women) participated in this study. Assessments included psychological profiles (kinesiophobia, self-reported mental health, self-efficacy, global mental health, and functional status via FAAM-Sport). Dynamic balance was evaluated using the SEBT composite and directional scores.</p><p><strong>Results: </strong>Multiple linear regression analyses indicated that the SEBT composite score was significantly predicted by self-efficacy, global mental health and TSK-11, explaining 40% of the variance (F-value = 7.82, p < 0.01). Further directional analysis revealed that posterior-medial reach was best predicted by self-efficacy, global mental health and TSK-11 (F-value = 9.05, p < 0.01; 44% variance), while posterior-lateral reach was similarly predicted by self-efficacy, and global mental health (F-value = 6.92, P = 0.003; 28% variance). Anterior reach performance was most strongly associated with self-efficacy and TSK-11 (F-value = 10.26, p < 0.01; 36% variance).</p><p><strong>Conclusions: </strong>The findings underscore the importance of psychological factors as key predictors of dynamic balance in CAI. Incorporating mental health assessments into physical rehabilitation may enhance treatment outcomes for individuals with CAI.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 2","pages":"e70152"},"PeriodicalIF":2.3,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13581079/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147582821","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Morphological Changes and MRI Characteristics of the Achilles Tendon in Amateur Marathon Runners With Different Running Experience.","authors":"Wanzhen Yao, Yong Chen, Siyu Dai, Jing Zhou, Xinmiao Mao, Yanjing Zhang, Jianping Ding, Jie Liu, Jie Huang","doi":"10.1002/jfa2.70125","DOIUrl":"10.1002/jfa2.70125","url":null,"abstract":"<p><strong>Background: </strong>With the escalating popularity of marathon running, Achilles tendon injuries, particularly gradual-onset Achilles tendon injury, have become common, often causing substantial training disruptions. However, the influence of running experience on the Achilles tendon structure in amateur runners remains largely unclear. This study aimed to investigate the association between running experience and asymptomatic Achilles tendon pathology as well as its structural changes.</p><p><strong>Methods: </strong>This was a cross-sectional observational study. Forty-eight amateur marathon runners were categorized into four groups based on running experience (1, 3, 5, and > 5 years), with 12 healthy nonrunners as controls. Inclusion and exclusion criteria were strictly applied. All participants underwent MRI scanning using a 3.0 T GE scanner. Two radiologists evaluated MRI scans for pathology and measured tendon length, thickness, volume, and cross-sectional area (CSA). Statistical analyses, including Shapiro-Wilk, ANOVA, Kruskal-Wallis H, and chi-squared tests, were conducted using SPSS 23.0.</p><p><strong>Results: </strong>Baseline characteristics showed no significant group differences. Qualitative analysis revealed that the prevalence of midportion tendinopathy, insertional tendinopathy, and retrocalcaneal bursitis increased significantly with longer running experience. Quantitative measurements indicated that tendon thickness, volume, and CSA were significantly greater in long-running groups compared to short-running and control groups, whereas tendon length remained unchanged. Interobserver reliability was excellent.</p><p><strong>Conclusion: </strong>In amateur marathon runners, running experience is associated with increased asymptomatic Achilles tendon pathology and morphological remodeling. Prolonged running may induce both adaptive and degenerative changes, highlighting the importance of MRI-based monitoring for early intervention in high-risk populations.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 1","pages":"e70125"},"PeriodicalIF":2.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12790804/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145953618","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence, Severity and Impact of Foot Pain in 419 Pregnant Participants: The Queensland Family Cohort Study.","authors":"J Raquel Fontes, Melinda M Franettovich Smith, Felix Leung, Vicki L Clifton, Julie Hides, M Dilani Mendis","doi":"10.1002/jfa2.70132","DOIUrl":"10.1002/jfa2.70132","url":null,"abstract":"<p><strong>Background: </strong>Many hormonal, anatomical and biomechanical changes occur during pregnancy that may contribute to lower limb musculoskeletal dysfunction, including foot pain. Previous international studies have reported variable rates of foot pain in this population, but there is a lack of prospective longitudinal investigations. Improving the current understanding of foot pain is important to inform the development of management interventions during and after pregnancy. This study aimed to investigate the self-reported prevalence, severity, frequency and impact of foot pain on work, activities and quality of life during pregnancy.</p><p><strong>Methods: </strong>Pregnant participants were recruited through the Queensland Family Cohort study conducted at a tertiary maternity hospital. Questionnaires were administered at enrolment (12-24 weeks' gestation) to collect demographics and at 24 weeks' gestation, 36 weeks' gestation and at the end of pregnancy (6 weeks postpartum) to measure the presence, severity and frequency of foot pain and symptoms and the impact of foot pain on work, activities and quality of life.</p><p><strong>Results: </strong>Four hundred and nineteen pregnant participants with a mean age of 32.2 (range 16-45) years and body mass index of 27 (range 17-52) were included. A high prevalence of foot pain was reported during pregnancy (44% up to 24 weeks; 56% up to 36 weeks, 54% up to the end of pregnancy). The severity of foot pain was mild to moderate and occasional in frequency. Foot pain had a mild to moderate impact on work, activities and quality of life during pregnancy. Participants with foot pain reported a lower perceived level of health during and at the end of pregnancy.</p><p><strong>Conclusion: </strong>Foot pain is a highly prevalent musculoskeletal problem that impacts work and quality of life during pregnancy. Pre-natal and post-natal care may provide an opportunity to assess and provide advice, treatment or appropriate referral for the management of foot pain.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 1","pages":"e70132"},"PeriodicalIF":2.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12862002/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146100869","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Structure and Function of the Achilles Tendon and Plantarflexors 1 Year Following Achilles Tendon Rupture in the United Kingdom: A Cross-Sectional Study.","authors":"Samuel Briggs-Price, Jitendra Mangwani, Alexander Kilcran, Anchal Prasad, Reihaneh Salimian, Seth O'Neill","doi":"10.1002/jfa2.70134","DOIUrl":"10.1002/jfa2.70134","url":null,"abstract":"<p><strong>Background: </strong>Achilles tendon rupture (ATR) is the most common tendon rupture affecting the lower limb. This study investigates Achilles tendon structure, strength and function 1 year or more after ATR.</p><p><strong>Methods: </strong>This cross-sectional study recruited individuals ≥ 12 months post ATR. Structure was assessed using ultrasound tissue characterisation (UTC) including cross-sectional area (CSA), aligned fibrillar structure (AFS), disorganised fibrillar structure (DFS) and echo type percentage. Strength was measured using maximal voluntary isometric contraction (MVIC) plantarflexor testing and the calf raise test. Patient-reported outcomes included the Achilles tendon rupture score (ATRS), EQ-5D-5L and general practice physical activity questionnaire (GPPAQ). Achilles tendon resting angle (ATRA) was used as an indirect measure of tendon elongation. The relationship between outcomes and time since ATR was analysed using linear regression adjusting for age, sex, ethnicity and body mass index (BMI). Between limb comparisons were made using paired t-tests.</p><p><strong>Findings: </strong>Sixty participants (mean age 55.2 years and 78.5% male) were assessed at a mean of 6.8 years post ATR. The affected tendon showed a 62% larger cross-sectional area, with 28.7 mm² (16%) DFS compared to 7.3 mm² (7%) on the nonaffected side (p < 0.001). Linear regression showed decreasing AFS with time postinjury (p = 0.04); no significant associations were found for CSA or DFS. Significant deficits were observed in plantarflexor strength and function, with MVIC and calf raise work 18% and 40% lower in the affected limb (p < 0.001). ATRA indicated tendon elongation in the affected limb of 6.7° (p < 0.001). Median ATRS was 83, EQ-5D index was 0.95 and VAS was 85; 93% were physically active based on the GPPAQ.</p><p><strong>Conclusion: </strong>Significant structural and functional deficits persist years after ATR, including increased tendon size, fibre disorganisation, reduced strength and tendon elongation. ATRS scores were consistent with previous nonsurgical immobilisation protocol outcomes in the United Kingdom. Longitudinal studies are needed to understand the trajectory of recovery following ATR.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 1","pages":"e70134"},"PeriodicalIF":2.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12893871/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146167486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reporting and Utilization of Patient-Reported Outcomes Measures in the Evaluation of Foot Orthoses Treatment: A Systematic Review.","authors":"Javier Jiménez-Guillén, Natalia Tovaruela-Carrión, Marta María Moreno-Fresco, Alfonso Martínez-Nova, Pedro V Munuera-Martínez","doi":"10.1002/jfa2.70148","DOIUrl":"10.1002/jfa2.70148","url":null,"abstract":"<p><strong>Purpose: </strong>Currently, there is no patient-reported outcome measure (PROM) specifically for evaluating foot orthoses treatments. This led us to ask the following question: What is the quality of the validated foot and ankle PROMs used to evaluate foot orthosis interventions? To do so, we analyzed the psychometric properties of these PROMs and identified the most widely used and those with the best measurement properties.</p><p><strong>Methods: </strong>Two literature searches were conducted in PubMed, Embase, Scopus, Web of Science, and the Cochrane Library. The methodological quality of the articles was assessed using the updated COSMIN checklist. Psychometric evidence for the properties investigated in the articles was assessed using the updated COSMIN criteria for good psychometric properties. Ratings of methodological quality and psychometric evidence were synthesized using the method of Schellingerhout et al. (2012).</p><p><strong>Results: </strong>A total of 205 articles were included, identifying 11 validated PROMs for foot and ankle used in the evaluation of foot orthoses. The Foot Function Index (FFI) and the Foot Health Status Questionnaire (FHSQ) were the most commonly used, whereas the Victorian Institute of Sport Assessment-Achilles tendon (VISA-A) questionnaire demonstrated the best measurement properties.</p><p><strong>Conclusion: </strong>The VISA-A, the Foot and Ankle Outcome Score (FAOS), and the Revised Foot Function Index (FFI-R) appear to be useful PROMs for evaluating foot orthoses treatments; however, more evidence is needed to make more robust and reliable statements.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 1","pages":"e70148"},"PeriodicalIF":2.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097690/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147470064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Australian Podiatry Research in Rheumatology: A Bibliometric Analysis.","authors":"Shan M Bergin, Polly Q X Lim, Hylton B Menz, Peta E Tehan, Matthew R Carroll","doi":"10.1002/jfa2.70128","DOIUrl":"10.1002/jfa2.70128","url":null,"abstract":"<p><strong>Background: </strong>To conduct a bibliographic analysis of English language foot and ankle research pertaining to rheumatology published by Australian authors.</p><p><strong>Methods: </strong>The Scopus database search was conducted to identify all Australian rheumatology articles published by podiatric authors in English from 1970 to 2024. Bibliometric analysis was performed using an open-source tool based on the R language. Citations, journals, authors, institutions and countries were described. Publications were manually categorised according to research type, level of evidence and funding source.</p><p><strong>Results: </strong>The search strategy yielded 89 eligible articles, which received a total of 2438 citations and were published by 200 authors. The most frequent journals were Arthritis Care & Research and Osteoarthritis and Cartilage each with 9 articles or 10% of total publications. The most published institution was La Trobe University (affiliation of 151 authors). Most of the Australian rheumatology articles focused on the evaluation of treatments and therapeutic interventions (n = 35; 39%) and 11 articles (12%) provided Level I evidence. Forty-two publications (47%) were supported by Category 1 funding, however, 29 (33%) reported no research funding.</p><p><strong>Conclusion: </strong>Rheumatology represents just 5% of Australian podiatry research. Despite this, it attracts high citation rates relative to number of publications and is well supported by Category 1 funding in comparison to other research fields. Funding sources outside of competitive Category 1 grants appear to be limited however, and research scope is narrow with a high number of evaluative studies conducted. Rheumatology research would benefit from an increase in available funding sources and a broader research scope that informs disease prevention and evidence-based clinical care.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 1","pages":"e70128"},"PeriodicalIF":2.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12864540/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108211","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring Experiences and Perspectives of Prescribed Foot Orthoses in People With Diabetes.","authors":"Niloofar Sedighi, Gordon Hendry, Jari Pallari, Ruth Barn","doi":"10.1002/jfa2.70130","DOIUrl":"10.1002/jfa2.70130","url":null,"abstract":"<p><strong>Background: </strong>Adherence to prescribed offloading among people with diabetes is often insufficient. Although factors influencing adherence with prescribed footwear have been well studied, uncertainties remain. Perceptions and views of people with diabetes on their prescribed foot orthoses, including areas for improvement, may offer important insights.</p><p><strong>Methods: </strong>Using a qualitative study design, a combination of online focus groups and individual interviews were employed to gain a deeper understanding of the experiences and perceptions of people at risk of diabetes-related foot ulcers regarding experiences of prescribed foot orthoses. All interviews and focus groups were recorded and transcribed verbatim. Transcribed data were coded, and thematic analysis was undertaken following a six-step thematic analysis framework.</p><p><strong>Findings: </strong>Eight people with diabetes at risk of developing foot ulcers who had been prescribed foot orthoses were included. Three major themes emerged from thematic analysis: (i) adherence and barriers to effective use of foot orthoses, which captured the role of health professionals as well as the interconnected relationship between footwear and foot orthoses, (ii) perceived benefits of foot orthoses and desired improvements, and (iii) anxiety and psychological impact, which highlighted how anxiety and fear can influence footcare behaviours, both as motivators and barriers.</p><p><strong>Conclusion: </strong>This study provides valuable insights into user experiences of prescribed foot orthoses and factors influencing foot orthoses-related behavioural choices; these findings may help researchers and healthcare professionals in designing and delivering foot orthoses that better meet the needs of users to enhance engagement with preventative strategies. Important considerations include the perception of balance and stability, the psychological impact of diabetes-related foot disease and the role of the healthcare professional in providing support both during and after foot orthoses provision.</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 1","pages":"e70130"},"PeriodicalIF":2.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12864537/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146108169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence and Incidence of Diabetes-Related Peripheral Neuropathy, Peripheral Artery Disease, Foot Ulcers and Lower Extremity Amputations in Ireland; A Systematic Review.","authors":"Sinead Kavanagh, Jennifer A Pallin, Ann Sinéad Doherty, Linda M O'Keeffe, Steven Gilmore, Peter A Lazzarini, Claire M Buckley","doi":"10.1002/jfa2.70147","DOIUrl":"10.1002/jfa2.70147","url":null,"abstract":"<p><strong>Introduction: </strong>Diabetes-related foot disease is a leading cause of global disease burden, however the prevalence and incidence of diabetes-related foot disease in Ireland is poorly understood. Up-to-date population-level estimates of the incidence and prevalence are imperative to support appropriate health service planning. This study examined the prevalence and incidence of diabetes-related foot disease in the Irish population.</p><p><strong>Methods: </strong>We systematically searched Pubmed, EMBASE and Lenus the Irish Health Research repository, for peer-reviewed articles published until August 2025. Publications reporting on prevalence and incidence of peripheral neuropathy, peripheral artery disease, foot ulceration or amputation in people with diabetes in Ireland, were eligible for inclusion. The Joanna Briggs Institute Prevalence (JBI) Critical Appraisal Tool was used to assess included studies methodological quality and establish the degree to which bias was addressed in the study's design and analysis. Results were synthesised descriptively according to study characteristics and outcomes.</p><p><strong>Results: </strong>Three studies met the inclusion criteria (n = 145,945), with varying outcome measurement methods. In community-based diabetes populations, peripheral neuropathy prevalence ranged from 15% to 39% (n = 1055) and peripheral artery disease prevalence ranged from 18% to 34% (n = 383). For the history of foot ulcers, prevalence was 3.7% (n = 563) and annual incidence was 2.6% (n = 383). One national population-based study (n = 144,710) reported incidence of amputation increased from 144.2 to 175.7 per 100,000 people with diabetes between 2005 and 2009.</p><p><strong>Conclusion: </strong>This review found there is a paucity of information on prevalence and incidence of diabetes-related foot disease in Ireland. However, these findings suggest that prevalence is similar to, if not lower than, global rates of peripheral neuropathy, peripheral artery disease outcomes and amputation incidence outcomes. High heterogeneity in populations and outcomes highlights the need for robust studies and consensus on diabetes-related foot outcome assessment. Establishing a national diabetes register could strengthen surveillance, identify high-risk groups and inform cost-effective public health planning.</p><p><strong>Trial registration: </strong>PROSPERO (CRD42023472904).</p>","PeriodicalId":49164,"journal":{"name":"Journal of Foot and Ankle Research","volume":"19 1","pages":"e70147"},"PeriodicalIF":2.3,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13097383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147469995","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}