Contact Lens & Anterior Eye最新文献

{"title":"Are scleral lenses underutilized? A call for greater awareness among healthcare professionals.","authors":"Maria K Walker","doi":"10.1016/j.clae.2025.102496","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102496","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102496"},"PeriodicalIF":3.7,"publicationDate":"2025-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006796","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic criteria for meibomian gland dysfunction: A prospective registry-based external validation analysis.","authors":"Michael T M Wang, Jordan M Cooper, Catherine J Jennings, Barry Power, James S Wolffsohn, Jennifer P Craig","doi":"10.1016/j.clae.2025.102487","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102487","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102487"},"PeriodicalIF":3.7,"publicationDate":"2025-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144975856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the editor RE \"Improved control efficacy of a novel aspherical orthokeratology lens compared with the traditional three-zone spherical lens in a single-blind randomized clinical trial\".","authors":"Dr Parth Aphale, Himanshu Shekhar, Shashank Dokania","doi":"10.1016/j.clae.2025.102495","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102495","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102495"},"PeriodicalIF":3.7,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144975944","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of wearing orthokeratology lenses for more than 5 years on the ocular surface of adolescents.","authors":"Xiao-Di Yang, Xin-Yan He, Yong Lyu, Wei-Qun Wang, Guang-Ming Wan","doi":"10.1016/j.clae.2025.102494","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102494","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of long-term orthokeratology (OK) lens wear on the ocular surface in adolescents.</p><p><strong>Methods: </strong>This cross-sectional case-control study included 30 adolescents who had worn OK lenses for more than 5 years and 30 demographically matched adolescents who wore spectacles. They were allocated to the experimental and control groups, respectively. The ocular surface condition, visual acuity, corneal fluorescein staining, tear meniscus height, non-invasive tear break-up time, tear film lipid layer characteristics, and upper and lower meibomian glands were assessed for all participants.</p><p><strong>Results: </strong>The adolescents who wore OK lenses for more than 5 years had lower average non-invasive tear break-up time (t = 2.099, p = 0.04), thinner tear film lipid layers (z = -2.657, p = 0.008), and higher rate of lower meibomian gland loss (MGL) (t = -5.541, p＜0.001) than those in the control group. Sex and refraction were independent predictors of lower MGL among long-term OK lens wearers. Males had a higher MGL rate than females (B = 16.308, 95 % confidence interval [CI]: 6.05, 26.56; p = 0.003). For every 1-diopter (D) increase in refraction (1D reduction in myopia), lower MGL decreased by 4.044 % (B = -4.044, 95 % CI: -8.00, -0.09; p = 0.045).</p><p><strong>Conclusions: </strong>Long-term OK lens wear by adolescents is associated with increased lower MGL and reduced tear film stability. Male sex and high myopia are risk factors for MGL. Regular follow-up and close monitoring of ocular surface health are recommended during extended OK lens use.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102494"},"PeriodicalIF":3.7,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144975873","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The impact of a hyaluronic acid derivative-containing care system on the wettability of PEG-coated rigid lenses.","authors":"Katsuhide Yamasaki, Haruki Nakagawa, Chika Motohiro, Lyndon Jones, Alex Hui","doi":"10.1016/j.clae.2025.102490","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102490","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigated how a contact lens care solution containing a hyaluronic acid derivative (HAD) impacts wettability of rigid lenses, with and without polyethylene glycol (PEG) surface coatings when tested in vitro.</p><p><strong>Methods: </strong>The adsorption of fluorescently labelled HAD and hyaluronic acid (HA) on to PEG and non-PEG coated lenses was compared by fluorescence quantification. The impact of HAD on sessile drop wettability was investigated on PEG and non-PEG coated lenses, which were cycled 300 times between an artificial tear solution (ATS) for 16 h and 8 h in a HAD or non-HAD containing solution. PEG-coated lenses were also rubbed with two commercial solutions over 30 cycles, to observe the impact on wettability. The total amount of lysozyme deposited on PEG-coated lenses when using these solutions after 30 cycles were also compared. Finally, to quantify the maintenance of the PEG coating, the amount of silicon detected nanometres under the lens surface when using either solution was determined using X-ray photoelectron spectroscopy.</p><p><strong>Results: </strong>Greater amounts of HAD adsorbed onto rigid lenses compared to HA. Use of a HAD-containing solution improved the wettability of non-PEG coated lenses, being similar to uncycled PEG-coated lenses after 21 cycles. The wettability of PEG-coated lenses was maintained with the HAD-containing solution, with less lysozyme deposition and similar levels of silicon detected as uncycled lenses. In contrast, the non-HAD containing solution decreased wettability over cycles, with PEG-coated lenses being similar to non-PEG coated lenses after 90 cycles. These lenses also experienced greater amounts of lysozyme deposition, and a greater amount of silicon detected below the lens surface.</p><p><strong>Conclusions: </strong>Incorporation of HAD into a contact lens care solution has positive effects on wettability of both PEG and non-PEG coated rigid lenses. In contrast, using a non-HAD containing solution decreased wettability over time, even for PEG-coated lenses.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102490"},"PeriodicalIF":3.7,"publicationDate":"2025-08-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144975937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of myopia control efficacy and retinal defocus in adolescents with moderate to high myopia when wearing aspheric lenses with different back optic zone diameters.","authors":"Jia Yu, Xinwei Yang, Yuehua Zhou","doi":"10.1016/j.clae.2025.102491","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102491","url":null,"abstract":"<p><strong>Objectives: </strong>To compare aspheric lenses with different back surface optic zones, analyze the defocus distribution in adolescents with moderate to high myopia and the changes in the eye axis after wearing the lenses, and provide a basis for the precise clinical fitting of orthokeratology lenses.​.</p><p><strong>Methods: </strong>A prospective randomized controlled study was conducted from 2021 to 2025. 346 adolescent myopia patients were selected at Beijing Ming Vision and Ophthalmology Clinic. They were divided into Group A (small optic zone, 5.0 mm) and Group B (conventional optic zone, 6.0 mm). This study systematically compared two types of orthokeratology lenses with different back surface optic zone designs, analyzed the changes in the relative defocus values of each quadrant and annular region after wearing the lenses for 6 months and 12 months, and explored the relationship between these changes and the growth of the eye axis.</p><p><strong>Results: </strong>The group with a small optic zone can generate a stronger myopic defocus effect in the region of 10° - 20°, while the group with a conventional optic zone shows more significant defocus effects in the region of 40° - 53° and the temporal region. In the nasal region, the myopic defocus value of the group with a small optic zone is higher, and the effect is enhanced as the wearing time prolongs. Multiple factors such as age, myopia degree, and pupil diameter are significantly correlated with the growth of the eye axis. Moreover, in different optic zone groups, the influence of each factor on the growth of the eye axis varies. Aspheric orthokeratology lenses with a small optic zone perform better in controlling the growth of the eye axis in adolescents with moderate to high myopia, and this effect is related to multiple ocular parameters.​.</p><p><strong>Conclusions: </strong>Aspheric orthokeratology lenses with a small optic zone have a better effect on controlling the eye axis of adolescents with moderate to high myopia. This is related to multiple parameters. They may provide a more precise mechanism for myopia control.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102491"},"PeriodicalIF":3.7,"publicationDate":"2025-08-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144975924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How well does non-invasive tear break-up time reflect patient-reported ocular discomfort? Insights from a clinical setting.","authors":"Michele Potenza, Silvia Odorici, Antonio Moramarco, Luigi Fontana, Piera Versura","doi":"10.1016/j.clae.2025.102488","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102488","url":null,"abstract":"<p><strong>Objective: </strong>To assess the correlation between non-invasive tear break-up time (NIBUT) and patient-reported symptoms in Dry Eye Disease (DED), and to explore whether NIBUT can serve as a supportive clinical parameter reflecting symptom severity.</p><p><strong>Methods: </strong>This single-centre retrospective study included data from 295 subjects (209 females and 86 males), complaining of chronic ocular discomfort and evaluated in a third-level specialized lab - Laboratory for Cornea and Ocular Surface Analysis, in the period between July 2023 and June 2024. NIBUT was measured with the CA-800 topographer (Topcon Healthcare, Tokyo, Japan), while subjective symptoms were estimated with the Ocular Surface Disease Index (OSDI), the Visual Analogue Score (VAS), and the Numerical Rate Score (NRS).</p><p><strong>Results: </strong>NIBUT did not correlate significantly with the subjective scores in the total population, including OSDI (r = -0.11, p = 0.43) and VAS (r = -0.06 and p = 0.56) correspondingly. Also, at the level of individual eyes, no significant relationship was demonstrated between NIBUT and NRS scores: for the right eye, r = -0.09, for the left eye r = -0.05; p = 0.12 and 0.39 respectively Only severe OSDI scores showed an inverse correlation with NIBUT values (r = -0.22; p = 0.005).</p><p><strong>Conclusion: </strong>Although NIBUT offers a standardized and non-invasive assessment of tear film stability, our data suggest that its correlation with patient-reported symptoms is limited and becomes clinically relevant only in subjects with severe OSDI scores. These findings suggest that NIBUT cannot independently diagnose DED, but may be useful as a complementary tool within a multimodal diagnostic approach to DED.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102488"},"PeriodicalIF":3.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144862547","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accommodation and convergence with spherical and toric soft contact lenses in astigmatic eyes.","authors":"Ankur Banik, Ganashree S, Nandini Kalyankumar Hadalgi, Ashwini K V","doi":"10.1016/j.clae.2025.102489","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102489","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the accommodation and convergence in astigmatic eyes with spherical and toric contact lenses.</p><p><strong>Methods: </strong>Total of 50 non-contact lens wearers, aged between 18 and 30 years with -0.75 to -2.00 D of astigmatism were enrolled in a double-masked, randomized, crossover study. Participants attended three clinical visits and were fitted with Purevision 2 Sphere and Toric (Bausch and Lomb Inc, Rochester, NY) contact lenses in a randomized order. The amplitude of accommodation was measured using a push-up technique with a Royal Air Force Ruler, and the near point of convergence was assessed using a vertical row of letters attached to a pen torch. All participants completed the Near ActivityVisual Questionnaire (NAVQ) and a forced-choice lens preference test.</p><p><strong>Results: </strong>The amount of amplitude of accommodation was significantly lower with toric contact lenses (7.86 ± 0.94 D) compared to spherical contact lenses (10.6 ± 0.84 D, p < 0.001). Similarly, near point of convergence was also significantly better with toric correction than with spherical correction (10.99 ± 1.06 cm vs. 12.78 ± 1.19 cm, p < 0.001). Participants reported improved near-visual performance with toric lenses (p < 0.001), and ninety percent (45 of 50) of participants preferred toric lenses (p < 0.0001).</p><p><strong>Conclusion: </strong>Astigmatic eyes showed reduced accommodative stress and improved convergence stability with toric contact lenses. This study emphasizes the importance of correcting astigmatism to optimize binocular vision and minimize visual fatigue in contact lens wearers.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102489"},"PeriodicalIF":3.7,"publicationDate":"2025-08-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144859840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intense pulsed light therapy to improve signs and symptoms of contact lens discomfort.","authors":"Srikanth Dumpati, Fatima Iqbal, Ajay Kumar Vijay, Jacqueline Tan, Mukesh Kumar, Mark Willcox","doi":"10.1016/j.clae.2025.102486","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102486","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of Intense Pulsed Light (IPL) therapy on signs and symptoms of Contact Lens Discomfort (CLD) in symptomatic contact lens (CL) wearers.</p><p><strong>Methods: </strong>A prospective, randomised, double masked study was conducted on 36 eyes of 18 CL wearers (IPL: n = 20; sham: n = 16) with a Contact Lens Dry Eye Questionnaire (CLDEQ-8) score ≥ 12. Participants received two IPL/sham treatments at three weeks intervals as per randomization. The sham group underwent simulated light exposure using a torch while the IPL device remained inactive. Meibomian gland expression was performed for both groups after each treatment. Symptom and clinical assessments included CLDEQ-8 questionnaire, non-invasive tear breakup time (NITBUT), tear film lipid layer thickness (TFLLT), tear meniscus height (TMH), tear volume, meibomian gland secretion score (MGSS), meiboscore (upper/lower eye lids), MG capping, pouting, foam, telangiectasia, hyperaemia (bulbar, limbal, & palpebral), palpebral roughness, corneal staining, and lid-parallel conjunctival folds (LIPCOF). Assessments were evaluated prior to treatment at baseline (D-0), and then at day 21(D-21), D-42, and D-90.</p><p><strong>Results: </strong>The IPL group showed a significant reduction in CLDEQ-8 score from 18.1 ± 1.9 at D-0 to 10.7 ± 1.1 at D-42 (p = 0.01), and improved meibomian gland secretion score (MGSS) at D-21 (p = 0.02) and D-42 (p < 0.01), MG capping, and pouting remained improved at D-90 (p < 0.01). MG foam, telangiectasia, bulbar hyperaemia and corneal staining improved significantly at D-42 (p < 0.01), but most changes diminished by D-90. The sham group showed no significant changes. No differences were observed in tear film parameters at any time point.</p><p><strong>Conclusion: </strong>IPL therapy, effectively reduced symptoms of CLD and improved meibomian gland function, though effect diminished within 69 days after the final treatment, underscoring the need for optimized treatment protocols.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102486"},"PeriodicalIF":3.7,"publicationDate":"2025-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144838377","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Optimizing scleral lens prescriptions: a comparison of algorithmic and conventional refraction and over-refraction in irregular corneas.","authors":"Rafaela S Alves-de-Carvalho, Rute J Macedo-de-Araújo, José M González-Méijome","doi":"10.1016/j.clae.2025.102485","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102485","url":null,"abstract":"<p><strong>Purpose: </strong>To compare the accuracy and consistency of subjective refraction using conventional methods versus an algorithm-based approach in patients with primary or secondary corneal irregularities, both with and without scleral lenses (SL).</p><p><strong>Methods: </strong>Nineteen eyes of ten subjects with irregular corneas underwent non-cycloplegic refraction using (I) retinoscopy followed by conventional subjective refraction (Conventional Refraction) to achieve maximum visual acuity with the maximum positive prescription, and (II) a Hartmann-Shack wavefront aberrometer (WAM 800) followed by an algorithm-based semi-automatic phoropter (Vision-R 800). Refraction measurements were conducted with both techniques, without and with SLs. Outcomes included spherical equivalent (M) and astigmatic components (J0 and J45), and monocular high and low-contrast visual acuity (HCVA and LCVA).</p><p><strong>Results: </strong>Without SLs, the mean difference in the spherical equivalent between methods was -0.80 ± 1.20 D (p = 0.001). With SLs, the mean difference was -1.04 ± 0.93 D (p = 0.001). Without SLs, monocular HCVA was 0.21 ± 0.20 LogMAR (range: -0.10 to 0.76) and 0.17 ± 0.14 LogMAR (range: -0.02 to 0.60) for Conventional Refraction and V-R 800 (p = 0.162), respectively. Monocular LCVA was 0.59 ± 0.22 LogMAR (range: 0.18 to 0.96) and 0.53 ± 0.20 LogMAR (range: 0.10 to 0.92) for Conventional Refraction and V-R 800, respectively (p = 0.060). With SLs, HCVA was 0.12 ± 0.16 LogMAR (range: -0.12 to 0.50) and 0.09 ± 0.11 LogMAR (range: -0.08 to 0.26) for Conventional Refraction and V-R 800 (p = 0.272), respectively. LCVA was 0.43 ± 0.20 LogMAR (range: 0.06 to 0.90) and 0.47 ± 0.15 LogMAR (range: 0.18 to 0.88), respectively (p = 0.287).</p><p><strong>Conclusions: </strong>Algorithm-based refraction method provided a more positive spherical equivalent than conventional methods, and both techniques resulted in comparable HCVA and LCVA. Algorithm-based refraction may offer an alternative for over-refraction in patients with irregular corneas during SLs.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102485"},"PeriodicalIF":3.7,"publicationDate":"2025-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144823051","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}