Contact Lens & Anterior Eye最新文献

{"title":"European trends in attitudes and strategies for myopia management in clinical practice.","authors":"Clara Martínez-Pérez, Jacinto Santodomingo-Rubido, Cesar Villa-Collar, Yasmin Whayeb, James S Wolffsohn","doi":"10.1016/j.clae.2025.102390","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102390","url":null,"abstract":"<p><strong>Background: </strong>Surveys conducted between 2015 and 2022 showed growing concern among European eye care practitioners about myopia management, though adoption of effective strategies varied. This study updates findings from 2024, analysing trends in attitudes and strategies for myopia management across Europe from 2015 to 2024.</p><p><strong>Methods: </strong>A cross-sectional online survey targeting European eye care practitioners was distributed in multiple languages through professional bodies. It assessed awareness of myopia prevalence, perceived efficacy and adoption of different myopia control strategies, and reasons for non-adoption.</p><p><strong>Results: </strong>Between 2015 and 2024, a total of 3,179 responses were collected from European practitioners, representing data across four survey years. Concern about pediatric myopia varied significantly in 2024 (P < 0.001), with Portugal reporting the highest concern (9.4 ± 1.0) and Sweden the lowest (5.9 ± 2.2). Orthokeratology combined with low-dose atropine was perceived as the most effective approach (60.8 ± 29.6), followed by solo orthokeratology (60.1 ± 25.0) and approved myopia control soft contact lenses (55.9 ± 23.4). Single-vision lenses (15.9 ± 22.9) and undercorrection (7.1 ± 16.6) were rated least effective. Since 2015, single-vision lens prescribing has declined, while myopia control spectacles and contact lenses, and combination therapies have increased. The major reasons preventing the prescription of myopia control methods in 2024 were cost (29.6 %), treatment availability (11.4 %) and inadequate information/knowledge (9.3 %). Factors such as patient age, refractive error, and parental myopia influenced treatment choices, with the factors being less influential in Russia compared to other countries (all p ≤ 0.001). All European countries reported that adopting measures to control myopia progression in 2024 were thought to improve patient loyalty (much more/more: 57.7 %) and improve job satisfaction (much more/more: 73.3 %), but it was perceived not to increase practice revenue (much more/more: 43.3 %).</p><p><strong>Conclusions: </strong>European practitioners are increasingly adopting evidence-based myopia control strategies, with most countries reporting relatively similar management practices. Offering myopia control enhanced patient loyalty and job satisfaction. However, barriers such as cost and perceived limited efficacy still impede broader adoption.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102390"},"PeriodicalIF":4.1,"publicationDate":"2025-03-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606798","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gabor patches training programme for neuroadaptation in multifocal contact lenses wearers.","authors":"Cristina Arroyo-Del Arroyo, Andrea Martínez-Pedreño, Sonia Menchen-Cañadas, David P Piñero, Gonzalo Carracedo","doi":"10.1016/j.clae.2025.102402","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102402","url":null,"abstract":"<p><strong>Objectives: </strong>To evaluate the effect of using a training programme (OPTIcTRAIN) using Gabor patches on visual performance during the fitting of multifocal contact lenses (CL) in neophyte wearers.</p><p><strong>Methods: </strong>A randomized longitudinal pilot study was conducted at the Optometry Clinic of Complutense University of Madrid (Spain). Participants were fitted with Comfilcon A multifocal CL and randomly assigned to either a Gabor group (receiving daily training) or a control group. Measurements were taken at baseline (V0), CL fitting day (V1) and after 10 (V2) and 20 days (V3) of CL wear, assessing visual acuity (VA) under different conditions (photopic and mesopic, high (HC) and low contrast (LC)) at far, intermediate and near distances, contrast sensitivity, and subjective measures using visual analogue scale and global rate changing scale (GRCS).</p><p><strong>Results: </strong>Twelve subjects (10 females, 2 males; mean age: 51.41 ± 5.41 years) were included. After 20 days, the Gabor group showed significantly higher HCVA (p = 0.016) and LCVA (p = 0.034) under photopic conditions at intermediate distances (-0.03 ± 0.05, 0.11 ± 0.09, respectively) compared to the control group (0.08 ± 0.07, 0.26 ± 0.10, respectively). No significant differences (p > 0.05) were observed between groups in VA under mesopic conditions. Contrast sensitivity did not significantly differ between groups at any visit. However, after 20 days, the Gabor group's contrast sensitivity (6 cpg) increased to values similar to baseline (V0: 6.33 ± 0.81 vs V1: 5.17 ± 0.75; p = 0.038; V1 vs V3: 6.00 ± 0.89, p = 0.025), whereas the control group experienced a significant decrease (V0: 6.50 ± 0.54 vs V1: 5.83 ± 0.75; p = 0.046). After 20 days, the Gabor group showed a significant improvement in halo perception (p = 0.043) on the GRCS (44.00 ± 4.04) compared to the control group (26.67 ± 7.47).</p><p><strong>Conclusions: </strong>A visual training program using Gabor patches may enhance high and low-contrast VA at intermediate distances under photopic conditions, improve contrast sensitivity for medium spatial frequencies, and enhance subjective perception of halos during initial adaptation to multifocal CL in presbyopic wearers.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102402"},"PeriodicalIF":4.1,"publicationDate":"2025-03-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143587649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ocular surface side effects of botulinum toxin type A injections in the treatment of lateral canthal wrinkles (Crow's Feet).","authors":"Jiaxin Han, Xue Yang, Qianwen Gong, Tingting Liu, Huifang Tu, Xiulan Lu, Fan Yang, Ruiting Ji, Liang Hu","doi":"10.1016/j.clae.2025.102389","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102389","url":null,"abstract":"<p><strong>Purpose: </strong>This study investigates the impact of Botulinum Toxin Type A (BoNT-A) injections for lateral canthal wrinkles on the ocular surface.</p><p><strong>Methods: </strong>A total of 30 patients (30 eyes) who received BoNT-A injections were followed over a three-month period. Evaluations included tear meniscus height (TMH), strip meniscometry test, fluorescein tear film break-up time (FTBUT), corneal staining score, meibomian gland orifice and meibum quality score. Observations were recorded at baseline, one week, one month, and three months post-injection.</p><p><strong>Results: </strong>Upper and total eyelid meiboscore, meibomian gland orifice obstruction, and meibum quality score peaked at three months post-injection, while FTBUT was shortest during the same period, with significant differences observed across time points (P < 0.05). Post-hoc analysis indicated a significant reduction in FTBUT between baseline and three months (P = 0.048). Corneal staining scores were highest at one week, with significant differences across time points (P < 0.001); post-hoc analysis revealed a significant difference between one week and three months (P = 0.037). No significant changes were found in TMH or strip meniscometry test score (P = 0.374, P = 0.732).</p><p><strong>Conclusions: </strong>BoNT-A injections may temporarily compromise ocular surface stability by decreasing tear film stability, disrupting meibomian gland function, and causing corneal epithelial disruption.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102389"},"PeriodicalIF":4.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical evaluation of the decentration in different designs of scleral lenses.","authors":"Ana Privado-Aroco, María Serramito, Gonzalo Valdes-Soria, María Romaguera, Alvaro Cuellar, Mohamed Filali, Cristina Pastrana, Gonzalo Carracedo","doi":"10.1016/j.clae.2025.102391","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102391","url":null,"abstract":"<p><strong>Purpose: </strong>To validate a simple and highly repeatable method of measuring the displacement of scleral lenses from the pupillary center and to quantify scleral lens decentration of two different designs of scleral lens landing zones: spheric (SLZ) and toric (TLZ), with the validated method.</p><p><strong>Methods: </strong>A prospective crossover study has been performed. Twenty patients (26.90 ± 3.03) with regular corneas participated voluntarily in the study and SLZ and TLZ landing zone Onefit™ MED scleral lenses were fitted. This study was divided into 2 phases. In the first phase, the validation of a new technique, using an image processing tool through the Matlab_R2017b software, to measure decentration was performed, compared with a subjective method consisting of a millimetric grid located in one of the slit lamp eyepieces. Intersession and interobserver repeatability were evaluated in the vertical and horizontal measurements of decentration with both methods. Once the best and higher repeatable method to assess decentration was found, phase 2 started and decentration of two different landing zone designs of scleral lenses were evaluated.</p><p><strong>Results: </strong>In the first phase, Matlab methodology for decentration analysis showed high repeatability for both horizontal and vertical axes (ICC ≥ 0.9), whereas the slit lamp method demonstrated lower repeatability (ICC < 0.5). Second phase showed a significant reduction in decentration after two hours of wear with TLZ design (p < 0.001), unlike the SLZ design, which had no significant changes.</p><p><strong>Conclusion: </strong>The measurement of contact lens decentration by image processing using the Matlab software showed a high intersubject and intersession repeatability. SLZ tends to decenter inferiorly and temporarily. A toric landing zone design allows better centration but does not completely reduce the problem of decentration in either the vertical or horizontal axis.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102391"},"PeriodicalIF":4.1,"publicationDate":"2025-03-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cost and benefits of availing specialty contact lenses for irregular cornea and ocular surface diseases from patient perspectives.","authors":"Janani Balaji, Madhumathi Subramanian, Swetha Saravanan, Anuradha Narayanan","doi":"10.1016/j.clae.2025.102385","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102385","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the cost of availing specialty contact lenses for irregular cornea and ocular surface diseases from the perspective of patients.</p><p><strong>Methods: </strong>Patients aged ≥18 years who purchased specialty contact lenses (corneal or scleral) for the management of irregular corneal or ocular surface diseases between August 2023 and January 2024 were included in this study. Using a micro-costing approach, cost per patient was estimated with the help of the institution's records, and via a semi-structured survey. The benefit-cost ratio was calculated as the valuation of benefits in terms of gain in productivity resulting from the use of contact lenses to the cost. Quality of life was measured using \"The National Eye Institute 25-Item Visual Function Questionnaire (NEI-VFQ 25)\". The NEI-VFQ 25 was administered during dispensing visits and after three months and was converted to quality-adjusted life years (QALYs) using the previously published results. A cost-effectiveness analysis was performed by estimating the cost per QALYs gained.</p><p><strong>Results: </strong>The total median (IQR) (USD) cost per patient to avail any specialty, corneal, and scleral contact lenses was ₹57,878(89,567) ($693), ₹21,907(20,420) ($262) and ₹1,10,316(69,514) ($1321) respectively. The total cost per patient was comparable to that of the low-income group ($750) based on the gross domestic product per capita of India and considerably less than that of the middle ($6,407) and high-income groups ($49,607). The discounted benefit-cost ratio was found to be 136:1. The cost per QALYs gained was found to be ₹1,35,899($1,628) and ₹1,56,440 ($1,874) for corneal and scleral lenses respectively.</p><p><strong>Conclusion: </strong>Specialty contact lenses are cost-beneficial and effective for patients with irregular cornea and ocular surface diseases. Considering economic differences, implementing health coverage plans, policies, or allocative decisions can make these lenses more affordable for every socioeconomic status people in India and reduce out-of-pocket expenses.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102385"},"PeriodicalIF":4.1,"publicationDate":"2025-02-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484441","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Goal framing of health promotion messages in contact lens wear.","authors":"Heidi Wagner, Dawn Lam, Andrew Loc Nguyen","doi":"10.1016/j.clae.2025.102387","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102387","url":null,"abstract":"<p><strong>Purpose: </strong>Appropriate framing of health information influences the adoption of health behaviors. This study explored whether (1) gain- or loss-framed health promotion messages, emphasizing positive or negative consequences, respectively, were more persuasive in adult contact lens wearers and (2) approach-oriented participants (participants that tend to seek rewards or attain goals) were motivated by gain-framed messages while avoidance-oriented participants (those driven to avoid consequences such as disease or injury) were motivated by loss-framed messages, as postulated by the congruency hypothesis.</p><p><strong>Methods: </strong>Gain- and loss-framed health promotion messages were created for three healthy contact lens-wearing habits (avoiding sleeping in contact lenses unless instructed to by an eye care provider, replacing lenses according to the manufacturer's recommended replacement schedule, and avoiding water exposure with contact lenses). Following local pilot testing and revision of health messages, data from 300 soft contact lens wearers aged 18-33 years (2/3 female) were collected via an electronic survey and online survey platform. Message persuasiveness was assessed by the participants with a visual analog scale. Avoidance and approach motivations were evaluated using the Behavioural Inhibition System/Behavioural Activation System scale. A linear mixed-effect model explored factors that influenced the persuasive effect of messages. Independent variables included frame type, media (infographic versus text), and participant characteristics. Pairwise Pearson correlations were used to explore relationships between avoidance/approach mechanisms and persuasiveness.</p><p><strong>Results: </strong>Participants rated loss-framed messages as more persuasive than gain-framed messages across the three habits: overnight wear (P < 0.001), lens replacement (P < 0.001), and water exposure (P < 0.001). The motivational orientation of the participants was not significantly correlated with persuasiveness but varied significantly with participant sex and history of a contact lens-related red eye.</p><p><strong>Conclusions: </strong>Loss-framing was more persuasive than gain-framing in this cohort. The results did not support the congruency hypothesis. Further study is needed to explore the clinical impact of these findings.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102387"},"PeriodicalIF":4.1,"publicationDate":"2025-02-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143473053","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rodent models for dry eye syndrome (DES).","authors":"Jingyun Zhu, Liu Liu, Jian Wu, Lang Bai","doi":"10.1016/j.clae.2025.102383","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102383","url":null,"abstract":"<p><p>Dry eye syndrome (DES) is a range of ophthalmic conditions characterized by compromised tear film homeostasis, resulting from various pathological factors and primarily manifesting as ocular discomfort and impaired ocular surface integrity. With the rise in screen time due to modern lifestyles, the prevalence of DES is increasing annually, posing a significant global public health challenge. Pathophysiologically, DES involves damage to the lacrimal functional unit (LFU), including the lacrimal glands, meibomian glands, and corneoconjunctival epithelium, highlighting its multifactorial etiology. Current treatments mainly focus on artificial tears for moisture replacement and anti-inflammatory therapies, but both are limited. Consequently, animal models are crucial for understanding the complex pathological mechanisms of DES and identifying potential therapeutic agents. Rodent eyes, with their structural and physiological similarities to human eyes and cost-effectiveness, have become widely used in DES research. This manuscript reviews the current understanding of DES pathogenesis and rodent models, discussing their strengths, weaknesses, and relevant genetic models. The aim is to furnish critical insights and provide a scholarly resource to propel future investigative endeavors into the pathogenesis of and therapy for DES.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102383"},"PeriodicalIF":4.1,"publicationDate":"2025-02-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143434141","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Ethnicity optimized indices enhance the diagnostic efficiency of early Keratoconus: A multicenter validation study.","authors":"Yan Huo, Ruisi Xie, Jing Li, Jie Hou, Haohan Zou, Yan Wang","doi":"10.1016/j.clae.2025.102382","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102382","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to evaluate the effectiveness of an ethnically-optimized corneal tomography and biomechanics index using artificial intelligence (AI) techniques for diagnosing early ectasia in Chinese populations and determine the diagnostic indices' sensitivity, specificity, and cutoff value for clinical practice.</p><p><strong>Methods: </strong>This multicenter case-control retrospective study included 1,012 eyes from three centers in China (Tianjin, Shaanxi, and Shandong). The groups included very asymmetric ectasia with normal topography (VAE-NT, n = 146), contralateral ectasia (VAE-E, n = 127), bilateral keratoconus (KC, n = 247), and normal eyes (NL, n = 492). The diagnostic efficiency of the Corvis Biomechanical Index (CBI), CBI for Chinese populations (cCBI), Tomographic and Biomechanical Index version 1 (TBIv1), TBI version 2 (TBIv2), and TBI for Chinese populations (cTBI) was assessed using receiver operating characteristic (ROC) curves. The diagnostic efficiency was compared using DeLong's test.</p><p><strong>Results: </strong>cTBI had the highest diagnostic accuracy for distinguishing NL from early ectasia (VAE-NT), with an area under the ROC (AUROC) of 0.93 at the cutoff value of 0.41, a sensitivity of 84.39 % and specificity of 92.67 %. cTBI diagnostic efficacy in early ectasia was better than TBIv2, TBIv1, cCBI, and CBI (Delong test, P < 0.01). It also had the best efficacy in distinguishing NL from \"disease\" (VAE-NT + VAE-E + KC), with an AUROC of 0.98 at the cutoff value of 0.66, sensitivity of 91.05 %, and specificity of 99.39 %. cTBI achieved 100 % sensitivity and specificity for distinguishing NL from clinical ectasia (VAE-E + KC) at a cutoff of 0.81.</p><p><strong>Conclusions: </strong>The ethnicity optimized cTBI index had good diagnostic efficiency for early ectasia in the Chinese population, highlighting the benefit of ethnic-specific parameter optimization.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102382"},"PeriodicalIF":4.1,"publicationDate":"2025-02-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143415897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of large language models for providing educational information in orthokeratology care.","authors":"Yangyi Huang, Runhan Shi, Can Chen, Xueyi Zhou, Xingtao Zhou, Jiaxu Hong, Zhi Chen","doi":"10.1016/j.clae.2025.102384","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102384","url":null,"abstract":"<p><strong>Background: </strong>Large language models (LLMs) are gaining popularity in solving ophthalmic problems. However, their efficacy in patient education regarding orthokeratology, one of the main myopia control strategies, has yet to be determined.</p><p><strong>Methods: </strong>This cross-sectional study established a question bank consisting of 24 orthokeratology-related questions used as queries for GTP-4, Qwen-72B, and Yi-34B to prompt responses in Chinese. Objective evaluations were conducted using an online platform. Subjective evaluations including correctness, relevance, readability, applicability, safety, clarity, helpfulness, and satisfaction were performed by experienced ophthalmologists and parents of myopic children using a 5-point Likert scale. The overall standardized scores were also calculated.</p><p><strong>Results: </strong>The word count of the responses from Qwen-72B (199.42 ± 76.82) was the lowest (P < 0.001), with no significant differences in recommended age among the LLMs. GPT-4 (3.79 ± 1.03) scored lower in readability than Yi-34B (4.65 ± 0.51) and Qwen-72B (4.65 ± 0.61) (P < 0.001). No significant differences in safety, relevance, correctness, and applicability were observed across the three LLMs. Parental evaluations rated all LLMs an average score exceeding 4.7 points, with GPT-4 outperforming the others in helpfulness (P = 0.004) and satisfaction (P = 0.016). Qwen-72B's overall standardized scores surpassed those of the other two LLMs (P = 0.048).</p><p><strong>Conclusions: </strong>GPT-4 and the Chinese LLM Qwen-72B produced accurate and beneficial responses to inquiries on orthokeratology. Further enhancement to bolster precision is essential, particularly within diverse linguistic contexts.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102384"},"PeriodicalIF":4.1,"publicationDate":"2025-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411350","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing scleral toricity induced lens flexure and contact disparity using anterior segment optical coherence tomography.","authors":"Eihab Eltantawy","doi":"10.1016/j.clae.2025.102386","DOIUrl":"https://doi.org/10.1016/j.clae.2025.102386","url":null,"abstract":"<p><strong>Purpose: </strong>To determine the influence of scleral toricity on the extent of lens contact and in-vivo flexure using anterior segment optical coherence tomography (AS-OCT), and to identify variables related to lens decentration.</p><p><strong>Methods: </strong>Scleral toricity at a chord of 15 mm was measured using Pentacam corneoscleral profilometry (CSP) from 10 healthy young participants (22 ± 2 years) with normal corneas. Participants were fitted with the same 16.0 mm rotationally symmetric scleral lens design (hexafocon A material). AS-OCT was used in conjunction with ImageJ analysis to document the disparity of lens contact at the 15 mm chord primary toric meridians and to assess lens flexure. Additionally, central fluid reservoir (FR) depth and lens decentration were measured.</p><p><strong>Results: </strong>A significant correlation was found between scleral toricity (mean 155 ± 95 μm) and both the magnitude of lens flexure, and the disparity in lens contact between the scleral primary toric meridians at the 15 mm chord diameter (r = 0.83, p = 0.003 and r_s = 0.83, p = 0.005 respectively). Mean lens decentration values were 0.30 ± 0.18 mm inferior-temporal net decentration, 0.26 ± 0.16 mm inferior decentration and 0.13 ± 0.1 mm temporal decentration. This was significantly associated with central FR depth (r_s = 0.91, p = 0.0005 and r_s = 0.73, p = 0.02 and r_s = 0.71, p = 0.03 respectively). No significant correlation was found between lens decentration and scleral toricity (p > 0.05).</p><p><strong>Conclusion: </strong>Scleral toricity was significantly associated with AS-OCT measured lens flexure and contact disparity at primary toric landing locations defined by profilometry. Reducing central FR depth appears to be a good strategy for improved lens centration. Whilst equalising lens contact along toric meridians is beneficial for addressing lens flexure, the influence of this on centration is less clear.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102386"},"PeriodicalIF":4.1,"publicationDate":"2025-02-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143400428","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}