Contact Lens & Anterior Eye最新文献

{"title":"The effect of overnight corneal refractive therapy (CRT) lenses on vision and corneal curvature in Chinese myopes: A prospective, multi-Centre study.","authors":"Jun Jiang, José A Vega, Chi Shing Fan, Xiaomei Qu, Lihua Li, Zhikuan Yang, Judy Fang Yiyun, Kelly Voltz","doi":"10.1016/j.clae.2026.102831","DOIUrl":"https://doi.org/10.1016/j.clae.2026.102831","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the effects of orthokeratology lenses (Paragon CRT® 100 [CRT 100] and CRT Dual Axis® [CRT-E], Paragon Vision Sciences, a CooperVision company) on vision and corneal curvature in myopic Chinese children and adults.</p><p><strong>Methods: </strong>This was a 12-month, multi-centre, bilateral-dispensing, single-arm clinical trial. Subjects were eligible for enrolment if both eyes had -0.50 to -4.00 DS, up to -1.50 DC, and no corneal abnormality. Uncorrected distance visual acuity (UDVA), manifest refraction spherical equivalent (MRSE), and corneal curvature were assessed at baseline and at follow-up visits after lens-wear periods of 1 day, 1 week, 2 weeks, and 1, 3, 6, 9, and 12 months.</p><p><strong>Results: </strong>Four sites in China enrolled 254 subjects aged 8 to 43 years (median: 11 years). Data were collected from both eyes of all subjects. Mean UDVA and MRSE were significantly improved compared to baseline values at all follow-up visits (P < 0.05). Mean UDVA improved by 0.44 ± 0.25 logMAR at Day 1 and 0.68 ± 0.20 logMAR at 1 month compared to baseline (0.65 ± 0.27 logMAR). Mean MRSE improved by 1.66 ± 0.92 D at Day 1 and 2.64 ± 0.69 D at 1 month compared to baseline (-2.66 ± 0.94 D). At 1 month, 94% of eyes had UDVA of ≤0.1 logMAR and - 0.50 D < MRSE < +0.50 D (472/502 eyes, 95%CI: 92-96%). Compared to baseline values, mean corneal curvatures (both steep and flat meridians) were significantly flatter at all follow-up visits (P < 0.001), and mean corneal astigmatism was slightly but significantly lower from the 1-week visit onward (P ≤ 0.007). There were no significant ocular adverse events.</p><p><strong>Conclusions: </strong>The CRT® orthokeratology lenses are able to temporarily flatten the cornea during overnight wear, temporarily correct myopia, and effectively improve UDVA after lens removal in a large proportion of predominantly paediatric Chinese eyes.</p>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"49 6","pages":"102831"},"PeriodicalIF":4.2,"publicationDate":"2026-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148898193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corrigendum to \"Effect of a head strap on the function of an eyelid warming compress\" [Contact Lens Anterior Eye 49 (2016) 102692].","authors":"Mou Saha, Ana Mustahsin, James S Wolffsohn, Sonia Trave-Huarte","doi":"10.1016/j.clae.2026.102828","DOIUrl":"https://doi.org/10.1016/j.clae.2026.102828","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"49 5","pages":"102828"},"PeriodicalIF":4.2,"publicationDate":"2026-08-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148867322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of management capability in healthcare practice.","authors":"Aditi Koche, Yang Zhao, Prasanta Kumar Dey, Shehzad A Naroo, Lawrence Willis","doi":"10.1016/j.clae.2026.102812","DOIUrl":"https://doi.org/10.1016/j.clae.2026.102812","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102812"},"PeriodicalIF":4.2,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Beyond visual acuity: evaluating functional vision in contact lens research.","authors":"Sotiris Plainis","doi":"10.1016/j.clae.2026.102811","DOIUrl":"https://doi.org/10.1016/j.clae.2026.102811","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102811"},"PeriodicalIF":4.2,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148708190","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Re: Banik et al. \"Accommodation and convergence with spherical and toric soft contact lenses in astigmatic eyes.\" Contact Lens and Anterior Eye 49 (2026):102489.","authors":"Sotiris Plainis","doi":"10.1016/j.clae.2026.102702","DOIUrl":"https://doi.org/10.1016/j.clae.2026.102702","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102702"},"PeriodicalIF":4.2,"publicationDate":"2026-07-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148551109","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Response to the Letter to the Editor.","authors":"","doi":"10.1016/j.clae.2026.102711","DOIUrl":"https://doi.org/10.1016/j.clae.2026.102711","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":" ","pages":"102711"},"PeriodicalIF":4.2,"publicationDate":"2026-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148473751","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Corneal nerve alterations in migraine: a systematic review of in vivo confocal microscopy and esthesiometry findings","authors":"Germán Mejía-Salgado,&nbsp;Alejandro Tello,&nbsp;Virgilio Galvis,&nbsp;Diana Vergara-Arenas,&nbsp;Cristhian Forero-Vargas,&nbsp;Alejandra de-la-Torre,&nbsp;Anat Galor","doi":"10.1016/j.clae.2026.102694","DOIUrl":"10.1016/j.clae.2026.102694","url":null,"abstract":"<div><h3>Objective</h3><div>To systematically evaluate structural and functional alterations of the subbasal corneal nerve plexus (SBCNP) in adults with migraine using in vivo confocal microscopy (IVCM) and corneal sensitivity testing, and to explore differences according to migraine subtype.</div></div><div><h3>Methods</h3><div>PubMed, Embase, Ovid, LILACS, VHL, and MedRxiv were searched through May 24, 2025, for studies assessing IVCM or corneal sensitivity in adults with migraine. Eligible designs included case-control and cross-sectional studies. Outcomes included corneal total branch density (CTBD), nerve fiber density (NFD), nerve fiber length (NFL), nerve branch density (NBD), tortuosity coefficient (TC), and corneal sensitivity. Risk of bias was assessed using tools designed for each study type, and Certainty of evidence was graded using the GRADE framework adapted to observational studies. Due to substantial methodological heterogeneity across studies, including differences in IVCM acquisition protocols, image analysis software, and mathematical definitions of nerve parameters, findings were synthesized narratively. The protocol was registered in PROSPERO (CRD420251105525).</div></div><div><h3>Results</h3><div>Eight studies, including 370 participants with migraine, met eligibility criteria. Most studies evaluating chronic migraine populations reported lower CTBD, NFD, and NFL compared with healthy controls, although findings remained heterogeneous across studies. Studies of episodic migraine showed contradictory findings, including preserved nerve parameters or isolated increases in TC. Two studies using different neurophysiological approaches to measure corneal sensitivity suggested altered peripheral and central trigeminal sensory processing in migraine individuals.</div></div><div><h3>Conclusion</h3><div>Available evidence suggests that chronic migraine may be associated with structural alterations of the SBCNP, whereas episodic migraine demonstrates more variable findings, including possible increases in nerve tortuosity. Functional studies suggest altered peripheral and central trigeminal sensory processing in migraine.</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"49 4","pages":"Article 102694"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148340760","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Orthokeratology versus extended depth-of-focus soft contact lenses for myopia control: a 12-month comparative study of axial elongation and corneal changes","authors":"Gema Corpus,&nbsp;Ainhoa Molina-Martin,&nbsp;David P. Piñero","doi":"10.1016/j.clae.2026.102698","DOIUrl":"10.1016/j.clae.2026.102698","url":null,"abstract":"<div><h3>Purpose</h3><div>To compare the efficacy of orthokeratology (OK) and extended depth-of-focus (EDOF) soft contact lenses in controlling myopia progression over a 12-month period.</div></div><div><h3>Methods</h3><div>Ambispective comparative study including 56 eyes from 28 myopic patients aged 6 to 16 years. Thirty eyes were fitted with EDOF soft contact lenses (prospective cohort), and 26 eyes with OK lenses (retrospective cohort). Axial length (AXL), spherical equivalent (SE), and binocular visual acuity (VA) were assessed at baseline, 6 months, and 12 months. Corneal parameters, including keratometry (K1,K2) and anterior chamber volume (ACV), were also evaluated.</div></div><div><h3>Results</h3><div>AXL increased significantly over time in both groups (<em>p</em> &lt; 0.001), with no significant differences between groups at any follow-up visit (all <em>p</em> &gt; 0.05). Mean axial elongation at 12 months was 0.05 ± 0.09 mm in the EDOF group and 0.11 ± 0.10 mm in the OK group. These values are lower than those reported in untreated myopic children. A small but statistically significant myopic shift in SE was observed in the EDOF group over time (<em>p</em> &lt; 0.001), whereas no significant refractive changes were detected in the OK group. Visual acuity remained stable in both groups throughout follow-up. Significant corneal changes were observed exclusively in the OK group, including reductions in K1 and K2 (<em>p</em> &lt; 0.001) and a decrease in ACV (<em>p</em> &lt; 0.05). Correlation analysis revealed that, in the OK group, baseline AXL and SE were significantly associated with axial elongation (<em>p</em> &lt; 0.05), indicating a baseline-dependent treatment response.</div></div><div><h3>Conclusion</h3><div>Both OK and EDOF soft contact lenses were associated with reduced axial elongation over a 12-month period, with no significant differences in efficacy between treatments. OK demonstrated a distinct profile characterized by corneal remodelling and a response influenced by baseline ocular parameters, whereas EDOF lenses showed a structurally neutral and more consistent effect across patients.</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"49 4","pages":"Article 102698"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148370494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comment on “Effect of orthokeratology on ocular dominance in Chinese myopic children: A 1-year longitudinal study”","authors":"Bing Sun,&nbsp;Kun Zheng","doi":"10.1016/j.clae.2026.102658","DOIUrl":"10.1016/j.clae.2026.102658","url":null,"abstract":"","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"49 4","pages":"Article 102658"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147845028","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Geometrically Centered and Offset Soft Multifocal Optics on Vision Quality in Myopes","authors":"Amity Ya-Ti Huang,&nbsp;Mary Avisado,&nbsp;Yu-Chi Tai,&nbsp;Randy Kojima,&nbsp;Matthew Lampa,&nbsp;John Hayes,&nbsp;Patrick Caroline","doi":"10.1016/j.clae.2026.102687","DOIUrl":"10.1016/j.clae.2026.102687","url":null,"abstract":"<div><h3><strong>Purpose</strong></h3><div>Center-distance multifocal soft contact lenses (CDMFSCLs) correct refractive error. However, their optical center is misaligned due to the temporal decentration of the soft contact lens on eye. This places the optics relatively inferonasal from the visual axis, potentially degrading vision. This study primarily investigated the effects of geometrically-centered optics (GCO) and offset optics (OFO, lens optics positioned over the visual axis) CDMFSCLs on wavefront aberrations in myopic adults. Secondary outcomes included visual performance and subjective ratings.</div></div><div><h3><strong>Methods</strong></h3><div>Thirty-four myopic adults with disease-free eyes participated in a randomized, crossover, double-masked, order-balanced study. All participants were fitted bilaterally with custom GCO and OFO CDMFSCL that shared identical designs, differing only in optic location. The amount and direction of lens decentration from the visual axis were measured using corneal topography maps over a plano GCO CDMFSCL. Wavefront aberrations, visual performance (acuity &amp; contrast sensitivity), and subjective rating were compared between GCO and OFO designs.</div></div><div><h3><strong>Results</strong></h3><div>All subjects completed the study. On average, GCO lenses displaced temporally (0.56 mm in the right eye, 0.59 mm in the left eye) and superiorly (0.29 mm in the right eye, 0.23 mm in the left eye). After Holm-Bonferroni correction, differences in ocular aberrations and physical discomfort remained statistically significant. However, improvements in contrast sensitivity at the 20/40 line under glare did not reach the adjusted significance threshold.</div></div><div><h3><strong>Conclusions</strong></h3><div>OFO CDMFSCLs improved optical alignment and reduced wavefront aberrations, but increased spherical aberration. Optimizing optical alignment may enhance visual quality, offering significant implications for lens customization.</div></div>","PeriodicalId":49087,"journal":{"name":"Contact Lens & Anterior Eye","volume":"49 4","pages":"Article 102687"},"PeriodicalIF":4.2,"publicationDate":"2026-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148310182","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}