Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"Rabdomiosarcoma prostático en un paciente de seis años evaluado mediante [18F]FDG PET/TC","authors":"","doi":"10.1016/j.remn.2024.500016","DOIUrl":"10.1016/j.remn.2024.500016","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 4","pages":"Article 500016"},"PeriodicalIF":1.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141415622","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Características de la imagen de un angiolipoma espinal atípico en PET/TC y resonancia magnética (RM)","authors":"Y. Li , R. Luo , W. Zhang, L. Li","doi":"10.1016/j.remn.2024.500015","DOIUrl":"10.1016/j.remn.2024.500015","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 4","pages":"Article 500015"},"PeriodicalIF":1.6,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141951756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad de la gammagrafía ósea como reflejo del estado nutritivo del paciente, un caso de escorbuto","authors":"J.A. Vázquez Gómez , M. Salvá Arteaga , I. Roncero Sánchez-Cano , A. Fernández Marín , M.P. Garrastachu Zumarán , M.Y. Ruiz del Prado","doi":"10.1016/j.remn.2024.500012","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500012","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500012"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación de la heterogeneidad molecular en tumores neuroendocrinos mediante PET/TC con [68Ga]Ga-DOTA-TOC y [18F]FDG","authors":"Z. Nogareda Seoane ,&nbsp;M.C. Mallón Araújo ,&nbsp;A. Calatayud Cubes ,&nbsp;C. Barberán Corral ,&nbsp;Y. Domínguez Novoa ,&nbsp;A. Cousillas Castiñeira ,&nbsp;N. Martínez Lago ,&nbsp;J.M. de Matías Leralta ,&nbsp;V. Pubul Nuñez","doi":"10.1016/j.remn.2024.500011","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500011","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of the study was evaluate the diagnostic performance of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/CT in patients with histologically proven neuroendocrine tumors (NETs), as well as the correlation of the visualized findings with the tumor grade.</p></div><div><h3>Material and methods</h3><p>We included 50 patients with NETs who underwent both [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/TC. The pooled sensitivity of both scans was compared, as well as [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG for each tumor grade (grade<!--> <!-->1 [G1], grade<!--> <!-->2 [G2] and grade<!--> <!-->3 [G3]). Also, the sensitivity of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG as a function of the continuous variable Ki-67 was investigated. Finally, the number of lesions detected by both PET radiopharmaceuticals for each tumor grade was compared.</p></div><div><h3>Results</h3><p>The pooled sensitivity of both PET/CT (96%) was higher than [⁶⁸Ga]Ga-DOTA-TOC (84%) and [¹⁸F]FDG (44%) separately, with statistically significant differences. The sensitivity of [⁶⁸Ga]Ga-DOTA-TOC was higher than [¹⁸F]FDG in both G1 (<em>P</em> <!-->=<!--> <!-->.004) and G2 (<em>P</em> <!-->&lt;<!--> <!-->.001). In G3 the performance of both scans detected disease in 100% of this subgroup. The sensitivity of [⁶⁸Ga]Ga-DOTA-TOC and [¹⁸F]FDG PET/CT correlated significantly with the Ki-67 proliferative index. In G2 patients the number of lesions detected with [⁶⁸Ga]Ga-DOTA-TOC was higher than [¹⁸F]FDG.</p></div><div><h3>Conclusions</h3><p>The performance of both PET/CT, particularly in G2 and G3, demonstrates the molecular heterogeneity of metastatic NETs and contributes to the selection of a more appropriate treatment, particularly in those high-grade patients who may benefit from radionuclide therapy (PRRT).</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500011"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detección de salpingitis mediante PET con 18F-FDG en paciente que presenta síndrome febril de origen desconocido","authors":"J.R. Garcia,&nbsp;A. Compte,&nbsp;L. Mont,&nbsp;S. Mourelo,&nbsp;P. Bassa,&nbsp;E. Riera","doi":"10.1016/j.remn.2024.500010","DOIUrl":"10.1016/j.remn.2024.500010","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500010"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141026485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Análisis radiómico PET intra y peritumoral para predecir la respuesta patológica en pacientes con cáncer de mama que reciben quimioterapia neoadyuvante","authors":"A. Aksu ,&nbsp;Z.G. Güç ,&nbsp;K.A. Küçüker ,&nbsp;A. Alacacıoğlu ,&nbsp;B. Turgut","doi":"10.1016/j.remn.2024.500002","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500002","url":null,"abstract":"<div><h3>Objective</h3><p>The aim of our study was to evaluate the contribution of ¹⁸Fluorine-fluorodeoxyglucose positron emission tomography (18F-FDG PET) radiomic data obtained from both the tumoral and peritumoral area in predicting pathological complete response (pCR) in patients with locally advanced breast cancer receiving neoadjuvant chemotherapy (NAC).</p></div><div><h3>Methods</h3><p>Female patients with a diagnosis of invasive ductal carcinoma who received NAC were evaluated retrospectively. The volume of interest (VOI) of the primary tumor (VOI-_T) was manually segmented, then a voxel-thick VOI was added around VOI-_T to define the peritumoral area (VOI-_PT). Morphological, intensity-based, histogram and texture parameters were obtained from VOIs. The patients were divided into two groups as pCR and non-complete pathological response (npCR). A «radiomic model» was created with only radiomic features, and a «patho-radiomic model» was created using radiomic features and immunohistochemical data.</p></div><div><h3>Results</h3><p>Of the 66 patients included in the study, 21 were in the pCR group. The only statistically significant feature from the primary tumor among patients with pCR and npCR was Morphological_Compacity-_T (AUC: 0.666). Between response groups, a significant difference was detected in 2 morphological, 1 intensity, 4 texture features from VOI-_PT; no correlation was found between Morphological_Compacity-_PT and NGLDM_contrast-_PT. The obtained radiomic model's sensitivity and accuracy values were calculated as 61.9% and 75.8%, respectively (AUC: 0.786). When HER2 status was added, sensitivity and accuracy values of the patho-radiomic model increased to 85.7% and 81.8%, respectively (AUC: 0.903).</p></div><div><h3>Conclusions</h3><p>Evaluation of PET peritumoral radiomic features together with the primary tumor, rather than just the primary tumor, provides a better prediction of the pCR to NAC in patients with breast cancer.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500002"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valor diagnóstico de la imagen PET/TC con [68Ga]Ga-FAPI en el tumor de células redondas pequeñas desmoplásticas","authors":"Y. Liu ,&nbsp;H. Liu ,&nbsp;Z. Wan ,&nbsp;Y. Chen ,&nbsp;J. Zhang","doi":"10.1016/j.remn.2024.500013","DOIUrl":"10.1016/j.remn.2024.500013","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500013"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2253654X24000209/pdfft?md5=3c33e724fb5728ac25df5b275aad77fd&pid=1-s2.0-S2253654X24000209-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141056832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Desarrollo y validación de un procedimiento alternativo para realizar los controles de pureza radioquímica de radiofármacos de 99mTc con un contador Geiger Müller","authors":"M.M. Gonzalez ,&nbsp;A.L. Poma ,&nbsp;N. Cuello ,&nbsp;A.L. Soldati","doi":"10.1016/j.remn.2024.500006","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500006","url":null,"abstract":"<div><h3>Background and objectives</h3><p>In a hospital radiopharmacy with 2a operational level, including the preparation of radiopharmaceuticals from prepared and approved reagent kits, it is common to have a single activimeter or dose calibrator for labeling and fractionation, and to perform the quality controls of the ^99mTc-radiopharmaceuticals. In certain cases, the accumulation of radioactive material or accidental contamination of the work area causes the background to exceed the limits to carry out the radiochemical purity analyses and it is necessary to look for viable alternatives. In this work, a Geiger Müller detector (equipped with a probe for measuring surface contamination) frequently used for radioprotection purposes, was validated as an alternative and its performance was compared against the activimeter for ^99mTc-radiopharmaceuticals.</p></div><div><h3>Materials and methods</h3><p>Using [^99mTc]pertechnetate, systematic studies of error analyses and detector response to activity concentration, activity and measurement time were carried out in liquid matrices and in paper. The results were compared against an activimeter calibrated for [^99mTc]Tc.</p></div><div><h3>Results</h3><p>The developed method was used to determine the radiochemical purity of the compounds [^99mTc]Tc-MDP and [^99mTc]Tc-MIBI by ascending paper chromatography tests, obtaining comparable values to those measured with an activimeter in the same system (within 1% uncertainty) and using the method of vial partitioning in a dedicated equipment.</p></div><div><h3>Conclusions</h3><p>This work demonstrates that a Geiger Müller detector with a probe for measuring surface contamination can be adequately used to replace other equipment in the control of radiochemical purity in the hospital radiopharmacy.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500006"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141073173","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Osificación de la hoz del cerebro en cáncer de mama metastásico","authors":"S. de la Torre Fernández,&nbsp;M.J. Tello Galán,&nbsp;B. Aradas Cabado,&nbsp;A.E. Seva Delgado,&nbsp;C.M. Hernández Heredia,&nbsp;A.J. Fernández Sánchez","doi":"10.1016/j.remn.2024.500001","DOIUrl":"10.1016/j.remn.2024.500001","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500001"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140794680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valor añadido de la PET/TC con [18F]fluorocolina en la valoración del hiperparatiroidismo secundario o terciario","authors":"S. Abouzian ,&nbsp;D.A. López-Mora ,&nbsp;A. Fernández-León ,&nbsp;C. Facundo ,&nbsp;P. Stefaneli ,&nbsp;A. Flotats","doi":"10.1016/j.remn.2024.500005","DOIUrl":"https://doi.org/10.1016/j.remn.2024.500005","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 3","pages":"Article 500005"},"PeriodicalIF":1.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141072503","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}