Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

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Equipo multidisciplinar de cirugía radioguiada: Alternativa de cambio al paradigma actual 多学科放射引导手术团队:改变现有模式的替代方案
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-03-01 DOI: 10.1016/j.remn.2023.12.001
J. Ribera-Perianes , M. Vega , X. Cases Moreno , J. Cordón , J. Cortés Gracia , P. Paredes , N. Sánchez-Izquierdo , A. Perissinotti , D. Fuster Pelfort , S. Vidal-Sicart
{"title":"Equipo multidisciplinar de cirugía radioguiada: Alternativa de cambio al paradigma actual","authors":"J. Ribera-Perianes ,&nbsp;M. Vega ,&nbsp;X. Cases Moreno ,&nbsp;J. Cordón ,&nbsp;J. Cortés Gracia ,&nbsp;P. Paredes ,&nbsp;N. Sánchez-Izquierdo ,&nbsp;A. Perissinotti ,&nbsp;D. Fuster Pelfort ,&nbsp;S. Vidal-Sicart","doi":"10.1016/j.remn.2023.12.001","DOIUrl":"10.1016/j.remn.2023.12.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Given the constant increase in the healthcare demand for examinations related to radio-guided surgery (RGS), our hospital adopted new professional profiles in the RGS team, in order to partially reduce the time spent by nuclear medicine physicians on this task.</p></div><div><h3>Aim</h3><p>To analyze the process of incorporating the profiles of Superior Diagnostic Imaging Technician (TSID) and Sentinel Node Referent Nurse (ERGC), evaluating their deployment in the procedures linked to the technique.</p></div><div><h3>Material and methods</h3><p>Analysis of RGS activity during the period 2018-2022, focusing on pre-surgical and surgical procedures related to breast cancer (BC) and malignant melanoma (MM), as they are those pathologies on which the transfer of care competencies was concentrated. Chronological evolution of the competencies assumed by the different profiles during their integration into the RGS team.</p></div><div><h3>Results</h3><p>RGS's healthcare activity during the analyzed period experienced an increase of 109%. BC and MM were the pathologies that accounted for by far the greatest demand for care. The transfer of competencies in these two pathologies occurred in a progressive and staggered manner, with 74% (460/622) of the administration phase being carried out by the ERGC and 64% (333/519) of the surgeries by the TSID in 2022.</p></div><div><h3>Conclusions</h3><p>The creation of a multidisciplinary RGS team that includes different professional profiles (NM, ERGC and TSID) is an effective strategy to respond to the increase in the complexity and number of all procedures related to RGS.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 91-99"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Utilidad de la gammagrafía ósea de tres fases en la valoración de la agresividad de las lesiones extraóseas. Dos patrones gammagráficos diferentes 三相骨闪烁成像在评估骨外病变侵袭性方面的作用。两种不同的扫描模式
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-03-01 DOI: 10.1016/j.remn.2023.11.004
P. Zaragoza-Ballester, M.J. Tabuenca
{"title":"Utilidad de la gammagrafía ósea de tres fases en la valoración de la agresividad de las lesiones extraóseas. Dos patrones gammagráficos diferentes","authors":"P. Zaragoza-Ballester,&nbsp;M.J. Tabuenca","doi":"10.1016/j.remn.2023.11.004","DOIUrl":"10.1016/j.remn.2023.11.004","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 121-123"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139021528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Detección de neoplasia oculta en un paciente con dermatomiositis mediante la PET/TC con [18F]AlF-NOTA-FAPI-04 y con [18F]FDG 通过 PET/CT 使用[18F]AlF-NOTA-FAPI-04 和[18F]FDG 检测皮肌炎患者的隐匿性肿瘤
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-03-01 DOI: 10.1016/j.remn.2023.11.002
Z. Ye , Y. Yao , J. Yin , Y. Kou , M. Zhao , Z. Cheng
{"title":"Detección de neoplasia oculta en un paciente con dermatomiositis mediante la PET/TC con [18F]AlF-NOTA-FAPI-04 y con [18F]FDG","authors":"Z. Ye ,&nbsp;Y. Yao ,&nbsp;J. Yin ,&nbsp;Y. Kou ,&nbsp;M. Zhao ,&nbsp;Z. Cheng","doi":"10.1016/j.remn.2023.11.002","DOIUrl":"https://doi.org/10.1016/j.remn.2023.11.002","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 119-120"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140164070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tumor desmoplásico de células redondas pequeñas con afectación ovárica en PET/TC con [18F]FDG 用[18F]FDG 进行 PET/CT 检查发现卵巢受累的脱鳞小圆形细胞瘤
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-01-01 DOI: 10.1016/j.remn.2023.08.006
Z. Zheng, P. Hu, Y. He, H. Shi
{"title":"Tumor desmoplásico de células redondas pequeñas con afectación ovárica en PET/TC con [18F]FDG","authors":"Z. Zheng,&nbsp;P. Hu,&nbsp;Y. He,&nbsp;H. Shi","doi":"10.1016/j.remn.2023.08.006","DOIUrl":"10.1016/j.remn.2023.08.006","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 55-56"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139301081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Valor pronóstico de los parámetros hematológicos y los parámetros metabólicos de la PET/TC con [18F]FDG en el cáncer de cabeza y cuello 头颈癌[18F]FDG PET/CT 血液学和代谢参数的预后价值
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-01-01 DOI: 10.1016/j.remn.2023.09.002
A. Baena García , J.R. Infante de la Torre , R. Barco Carbonero , A. Martínez Esteve , V. Vera Barragan , J. Serrano Vicente , P. Jiménez Granero , A. Utrera Costero
{"title":"Valor pronóstico de los parámetros hematológicos y los parámetros metabólicos de la PET/TC con [18F]FDG en el cáncer de cabeza y cuello","authors":"A. Baena García ,&nbsp;J.R. Infante de la Torre ,&nbsp;R. Barco Carbonero ,&nbsp;A. Martínez Esteve ,&nbsp;V. Vera Barragan ,&nbsp;J. Serrano Vicente ,&nbsp;P. Jiménez Granero ,&nbsp;A. Utrera Costero","doi":"10.1016/j.remn.2023.09.002","DOIUrl":"10.1016/j.remn.2023.09.002","url":null,"abstract":"<div><h3>Aim</h3><p>To determine the usefulness of neutrophil/lymphocyte (N/L) and platelet/lymphocyte (P/L) ratios as well as quantitative [<sup>18</sup>F]FDG PET/CT parameters as prognostic factors for overall survival (OS), cancer-specific survival (CSS) and progression-free survival (PFS) in patients with head and neck squamous cell carcinoma (HyN).</p></div><div><h3>Material and methods</h3><p>Sixty-six patients (56 men) diagnosed with HyN carcinoma were retrospectively assessed over an 8-year interval. Maximum SUV (SUVmax), metabolic tumour volume (MTV) and total lesion glycolysis (TLG) parameters were determined from the PET/CT study at diagnosis. After treatment with chemoradiotherapy, patient survival was assessed. The Cox regression model and the Kaplan-Meier method were used to analyse prognostic factors and survival curves.</p></div><div><h3>Results</h3><p>Median follow-up was 50.4<!--> <!-->months, with 39 recurrences-progressions and 39 deaths. In the univariate analysis, metabolic parameters, except SUVmax, were predictive factors for all three survivals and the two blood parameters were predictive for OS and EFS. TLG was the only predictive factor in the multivariate analysis. The three survival curves were significantly different for the metabolic parameters and the OS curve for the N/L ratio. Correlations were seen between N/L ratio, MTV and TLG. No correlations were demonstrated between P/L ratio and metabolic parameters.</p></div><div><h3>Conclusion</h3><p>The use of haematological and metabolic markers would allow to identify patients with a high risk of recurrences and poor survival and to individualise treatment by applying more aggressive therapies.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 31-38"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Áreas de respeto graso que simulan metástasis hepáticas en PET/TC con 18F-FDG 18F-FDG PET/CT 上模拟肝转移的脂肪尊区
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-01-01 DOI: 10.1016/j.remn.2023.09.005
P. Oliván-Sasot , C. la Parra-Casado , A.C. Orozco-Molano , L. Camacho-Berne , T. Peris-Conejero , A. Tembl-Ferrairo
{"title":"Áreas de respeto graso que simulan metástasis hepáticas en PET/TC con 18F-FDG","authors":"P. Oliván-Sasot ,&nbsp;C. la Parra-Casado ,&nbsp;A.C. Orozco-Molano ,&nbsp;L. Camacho-Berne ,&nbsp;T. Peris-Conejero ,&nbsp;A. Tembl-Ferrairo","doi":"10.1016/j.remn.2023.09.005","DOIUrl":"10.1016/j.remn.2023.09.005","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 59-60"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135810508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Análisis visual y semicuantitativo del 6-[18F]FDOPA PET/TC en pacientes con tumores cerebrales ante la sospecha de recurrencia tumoral versus radionecrosis 对疑似肿瘤复发与放射性坏死的脑肿瘤患者进行 6-[18F]FDOPA PET/CT 的可视化和半定量分析
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-01-01 DOI: 10.1016/j.remn.2023.08.004
M. Suárez-Piñera , L. Rodriguez-Bel , M. Alemany , A. Pons-Escoda , M. Pudis , A. Coello , G. Reynes , N. Vidal , M. Cortes-Romera , M. Macia
{"title":"Análisis visual y semicuantitativo del 6-[18F]FDOPA PET/TC en pacientes con tumores cerebrales ante la sospecha de recurrencia tumoral versus radionecrosis","authors":"M. Suárez-Piñera ,&nbsp;L. Rodriguez-Bel ,&nbsp;M. Alemany ,&nbsp;A. Pons-Escoda ,&nbsp;M. Pudis ,&nbsp;A. Coello ,&nbsp;G. Reynes ,&nbsp;N. Vidal ,&nbsp;M. Cortes-Romera ,&nbsp;M. Macia","doi":"10.1016/j.remn.2023.08.004","DOIUrl":"10.1016/j.remn.2023.08.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Amino acid PET is a tool recommended by the main neuroimaging societies in the differential diagnosis between radionecrosis (RNC) and tumour recurrence (TR) in brain tumours, but its use in our country is still limited. The aim of this work is to present our experience with 6-[<sup>18</sup>F]FDOPA PET/CT (FDOPA) in brain tumours (primary and M1), comparing these results with other published results.</p></div><div><h3>Material and methods</h3><p>Retrospective study of 62 patients with suspected tumour recurrence (TR): 42 brain metastases (M1) and 20 primary, who underwent FDOPA. Images were analysed visually and semi-quantitatively, obtaining SUV<sub>max</sub> and SUV<sub>max</sub>lesion/SUV<sub>max</sub>striatum (L/S) and SUV<sub>max</sub>lesion/SUV<sub>max</sub>cortex (L/C) ratios. The diagnostic validity of PET was analysed and the best performing cut-off points were calculated. PET results were compared with clinical-radiological follow-up and/or histopathology.</p></div><div><h3>Results</h3><p>TR was identified in 49% of M1 and 76% of brain primaries. The best performing FDOPA interpretation was visual and semi-quantitative, with a sensitivity and specificity in primaries of 94% and 80% and in M1s of 96% and 72% respectively. The cut-off points with the best diagnostic performance were L/C1.44 in M1 and L/C1.55 in primaries. There are discrepant results with other published results.</p></div><div><h3>Conclusion</h3><p>FDOPA PET/CT is a useful tool in the differential diagnosis between recurrence and RNC in brain tumours. It is needed a standardization to contribute to homogenise FDOPA results a inter-centre level.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 6-13"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135606285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Innovación continuada en cirugía radioguiada de precisión 精准放射引导手术的不断创新
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-01-01 DOI: 10.1016/j.remn.2023.10.002
Sergi Vidal-Sicart , Elena Goñi , Isaac Cebrecos , Mª Eugenia Rioja , Andrés Perissinotti , Catalina Sampol , Oscar Vidal , David Saavedra-Pérez , Ada Ferrer , Carles Martí , José Ferrer Rebolleda , Mª José García Velloso , Jhon Orozco-Cortés , Berta Díaz-Feijóo , Aida Niñerola-Baizán , Renato Alfredo Valdés Olmos
{"title":"Innovación continuada en cirugía radioguiada de precisión","authors":"Sergi Vidal-Sicart ,&nbsp;Elena Goñi ,&nbsp;Isaac Cebrecos ,&nbsp;Mª Eugenia Rioja ,&nbsp;Andrés Perissinotti ,&nbsp;Catalina Sampol ,&nbsp;Oscar Vidal ,&nbsp;David Saavedra-Pérez ,&nbsp;Ada Ferrer ,&nbsp;Carles Martí ,&nbsp;José Ferrer Rebolleda ,&nbsp;Mª José García Velloso ,&nbsp;Jhon Orozco-Cortés ,&nbsp;Berta Díaz-Feijóo ,&nbsp;Aida Niñerola-Baizán ,&nbsp;Renato Alfredo Valdés Olmos","doi":"10.1016/j.remn.2023.10.002","DOIUrl":"10.1016/j.remn.2023.10.002","url":null,"abstract":"<div><p>Since its origins, nuclear medicine has faced technological changes that led to modifying operating modes and adapting protocols. In the field of radioguided surgery, the incorporation of preoperative scintigraphic imaging and intraoperative detection with the gamma probe provided a definitive boost to sentinel lymph node biopsy to become a standard procedure for melanoma and breast cancer.</p><p>The various technological innovations and consequent adaptation of protocols come together in the coexistence of the disruptive and the gradual. As obvious examples we have the introduction of SPECT/CT in the preoperative field and Drop-in probes in the intraoperative field. Other innovative aspects with possible application in radio-guided surgery are based on the application of artificial intelligence, navigation and telecare.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 39-54"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139300320","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
¿Es yodorrefractario? Los primeros rastreos con yodo-131 tras el tratamiento y los primeros rastreos diagnósticos con yodo-123 pueden subestimar la carga de enfermedad metastásica en el cáncer de tiroides: a propósito de un caso 是难治性碘尿吗?治疗后首次碘-131扫描和首次诊断性碘-123扫描可能低估甲状腺癌转移性疾病的负担:病例报告
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-01-01 DOI: 10.1016/j.remn.2023.09.006
L. Foppiani , F. Fiz , M. Dezzana , M. Massollo , G. Bottoni , A. Piccardo
{"title":"¿Es yodorrefractario? Los primeros rastreos con yodo-131 tras el tratamiento y los primeros rastreos diagnósticos con yodo-123 pueden subestimar la carga de enfermedad metastásica en el cáncer de tiroides: a propósito de un caso","authors":"L. Foppiani ,&nbsp;F. Fiz ,&nbsp;M. Dezzana ,&nbsp;M. Massollo ,&nbsp;G. Bottoni ,&nbsp;A. Piccardo","doi":"10.1016/j.remn.2023.09.006","DOIUrl":"10.1016/j.remn.2023.09.006","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 61-62"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139188660","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
El papel de la PET/TC con 2-[18F]FDG en la enfermedad de Erdheim-Chester 2-[18F]FDG PET/CT 在埃尔德海姆-切斯特病中的作用
IF 1.2 4区 医学
Revista Espanola De Medicina Nuclear E Imagen Molecular Pub Date : 2024-01-01 DOI: 10.1016/j.remn.2023.08.005
M. Pudis , A. Palomar Muñoz , X. Solanich Moreno , J.J. Robles Barba , G. Rocamora Blanch , L. Rodríguez Bel , J.A. Narváez , M. Cortés Romera
{"title":"El papel de la PET/TC con 2-[18F]FDG en la enfermedad de Erdheim-Chester","authors":"M. Pudis ,&nbsp;A. Palomar Muñoz ,&nbsp;X. Solanich Moreno ,&nbsp;J.J. Robles Barba ,&nbsp;G. Rocamora Blanch ,&nbsp;L. Rodríguez Bel ,&nbsp;J.A. Narváez ,&nbsp;M. Cortés Romera","doi":"10.1016/j.remn.2023.08.005","DOIUrl":"10.1016/j.remn.2023.08.005","url":null,"abstract":"<div><h3>Objective</h3><p>To analyze the body distribution of Erdheim-Chester disease (ECD) and determine the utility of 2-[<sup>18</sup>F]FDG PET/CT compared to other imaging techniques. Additionally, to assess the aggressiveness and extent of the disease based on the presence/absence of the BRAF<sup>V600E</sup> mutation.</p></div><div><h3>Materials and methods</h3><p>The 2-[<sup>18</sup>F]FDG PET/CT scans of all patients diagnosed with ECD between 2008 and 2021 were reviewed, including 19 patients. The affected territories were classified as detectable by PET/CT or detectable only by other imaging techniques (bone scintigraphy, contrast-enhanced CT, or MRI). Descriptive analysis and correlation of the BRAF mutation with the affected organs and maximum SUV were performed using the Student's t-test.</p></div><div><h3>Results</h3><p>Out of the 19 patients (14 males; mean age 60.3<!--> <!-->years), 11 had the BRAF<sup>V600E</sup> mutation. A total of 127 territories (64 organ-systems) affected were identified using different imaging modalities, of which 112 were detected by PET/CT, and an additional 15 territories were solely identified by cerebral and cardiac MRI. The presence of BRAF<sup>V600E</sup> mutation was associated with greater organ involvement (<em>P</em> <!-->&lt;<!--> <!-->.05) without differences in SUVmax (<em>P</em> <!-->&gt;<!--> <!-->.05).</p></div><div><h3>Conclusion</h3><p>2-[<sup>18</sup>F]FDG PET/CT is a highly effective diagnostic tool in patients with ECD, detecting the majority of affected territories. MRI was the only imaging modality with additional findings in territories showing high physiological uptake of 2-[<sup>18</sup>F]FDG (cerebral and cardiac). The presence of the BRAF<sup>V600E</sup> mutation correlated with a higher extent of the disease.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 14-22"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139393564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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