Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"Importancia pronóstica de las distancias normalizadas entre el punto de captación máxima estandarizado del radiotrazador y el centro tumoral en la PET/TC con 18F-FDG en el carcinoma de células escamosas de cabeza y cuello","authors":"S.-P. Hong ,&nbsp;S.M. Lee ,&nbsp;I.D. Yoo ,&nbsp;I.Y. Jo ,&nbsp;Y.K. Won ,&nbsp;M.-S. Kim ,&nbsp;H.J. Choi ,&nbsp;J. Won Lee ,&nbsp;S.J. Jang","doi":"10.1016/j.remn.2025.500103","DOIUrl":"10.1016/j.remn.2025.500103","url":null,"abstract":"<div><h3>Objective</h3><div>The maximum ¹⁸F-FDG uptake of a cancer lesion has been found to relocate from the center to the periphery during progression. This behavior proposes that the normalized distances from the hotspot of radiotracer uptake to the tumor centroid (NHOC) and to the tumor perimeter (NHOP) could serve as novel geometric PET parameters indicative of tumor aggressiveness. This study aimed to explore the prognostic relevance of NHOC and NHOP in ¹⁸F-FDG PET/CT for predicting the response to concurrent chemoradiotherapy (CCRT) and progression-free survival (PFS) in patients with head and neck squamous cell carcinoma.</div></div><div><h3>Materials and methods</h3><div>We retrospectively reviewed 116 head and neck squamous cell carcinoma patients who received CCRT and were assessed with pre-treatment (PET1) and 3 months post-treatment PET/CT (PET2). Along with conventional PET parameters, NHOC and NHOP for primary tumors on PET1 and the percent changes in NHOC and NHOP between PET1 and PET2 were measured.</div></div><div><h3>Results</h3><div>Of all the PET1 parameters assessed, NHOC was the most effective in predicting the CCRT response, achieving an area under the receiver operating characteristic curve of 0.645. In multivariate logistic regression and survival analysis, NHOC identified as an independent predictor for both complete metabolic response (p<!--> <!-->=<!--> <!-->0.028) and PFS (p<!--> <!-->=<!--> <!-->0.006). In a subgroup of 46 patients exhibiting residual primary tumors on PET2, both the percent changes in NHOC (p<!--> <!-->=<!--> <!-->0.048) and NHOP (p<!--> <!-->=<!--> <!-->0.041) were significantly associated with PFS.</div></div><div><h3>Conclusions</h3><div>NHOC and the percent changes in NHOC and NHOP following CCRT may serve as effective ¹⁸F-FDG PET/CT parameters for predicting clinical outcomes in head and neck squamous cell carcinoma patients.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500103"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557566","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Síndrome de activación macrofágica en un paciente pediátrico: hallazgos en PET/TC con 18F-FDG","authors":"J.P. Suárez Fernández,&nbsp;M.L. Domínguez Grande,&nbsp;C. Vigil Díaz,&nbsp;B. Fernández Llana,&nbsp;N. Martín Fernández,&nbsp;F.M. González García","doi":"10.1016/j.remn.2025.500183","DOIUrl":"10.1016/j.remn.2025.500183","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500183"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557694","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad de la PET/TC con [18F]FDG más allá de la estadificación: importancia pronóstica de la sarcopenia y del metabolismo del tejido adiposo en el carcinoma esofágico","authors":"M.N. Acar Tayyar ,&nbsp;M. Öner Tamam ,&nbsp;G. Buğrahan Babacan ,&nbsp;M. Can Şahin ,&nbsp;H. Özçevik ,&nbsp;N. Gürdal ,&nbsp;K. Atakır","doi":"10.1016/j.remn.2024.500090","DOIUrl":"10.1016/j.remn.2024.500090","url":null,"abstract":"<div><h3>Aim</h3><div>This study aimed to investigate the relationship between PET and CT parameters and sarcopenia, adipose tissue, and tumor metabolism in esophageal carcinoma (EC) and its impact on survival in EC.</div></div><div><h3>Method</h3><div>Our study included 122 EC patients who underwent PET/CT for staging. Muscle and adipose tissue characteristics were evaluated, including lumbar (L3) and cervical (C3) muscle areas, psoas major (PM) and sternocleidomastoid muscle (SCM) parameters, and PET parameters for visceral and subcutaneous adipose tissue (SAT). Sarcopenia was determined using CT images, with a threshold for muscle tissue at the L3 vertebral level, and its impact on overall survival (OS) was investigated.</div></div><div><h3>Results</h3><div>Sarcopenia was detected in 48 patients. SULmax in the primary tumor (PT) was significantly higher in sarcopenic patients (SP). The frequency of distant metastasis was higher in SP and OS was significantly lower. In the locally advanced stage, sarcopenia status decreased survival. L3, PM, C3, and SCM muscle areas were highly correlated. Subcutaneous adipose tissue SUVmax was significantly increased in SP and those with distant metastasis. Univariate analysis identified PT SULmax, PT SUVmean, PT TLG, lymph node and distant metastasis, SAT SUVmax, and sarcopenia as poor prognostic factors, while multivariate analysis confirmed BMI, distant metastasis, PT SUVmean, PT TLG as independent predictors of OS.</div></div><div><h3>Conclusion</h3><div>This study demonstrated that sarcopenia, linked to reduced survival, correlates with primary tumor SULmax, distant metastasis, and subcutaneous tissue PET parameters, exerting a notable impact on survival, particularly in locally advanced stages. Attenuation-corrected CT can be used instead of diagnostic CT, and sarcopenia can be diagnosed using not only L3 but also C3 slices.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500090"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET/TC con 18F-FDG de doble tiempo en un caso de linfoma extranodal primario hepático de zona marginal del tejido linfoide asociado a mucosa","authors":"R. Yang,&nbsp;Z. Zheng,&nbsp;Y. Lin,&nbsp;H. Shi","doi":"10.1016/j.remn.2025.500105","DOIUrl":"10.1016/j.remn.2025.500105","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500105"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557568","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluación del angiosarcoma cardíaco mediante [18F]FDG PET/TC","authors":"B. Hervás-Sanz ,&nbsp;N. Ruiz-Roig ,&nbsp;L. Rodríguez-Bel ,&nbsp;L.M. Gràcia-Sánchez ,&nbsp;M. Cortés-Romera ,&nbsp;P.C. Notta","doi":"10.1016/j.remn.2025.500131","DOIUrl":"10.1016/j.remn.2025.500131","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500131"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"PET/TC con [18F]FDG en el diagnóstico y evaluación de respuesta al tratamiento en un paciente con sarcoidosis sistémica","authors":"J.P. Suárez Fernández,&nbsp;S. Naranjo Sancho,&nbsp;M.L. Domínguez Grande,&nbsp;C. Vigil Díaz,&nbsp;N. Martín Fernández,&nbsp;F.M. González García","doi":"10.1016/j.remn.2025.500135","DOIUrl":"10.1016/j.remn.2025.500135","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500135"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557693","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Actualización del procedimiento y guía de interpretación del estudio PET cerebral con 18F-FDG","authors":"C. Vigil Díaz ,&nbsp;P. Paredes Rodríguez ,&nbsp;A. Perissinotti ,&nbsp;E. Fernando Guillén ,&nbsp;D.A. López Mora ,&nbsp;J.A. Lojo Ramírez ,&nbsp;P. Aguiar Fernández ,&nbsp;V. Camacho Martí ,&nbsp;M. Nieves Cabrera-Martín ,&nbsp;por el grupo de Trabajo de Neuroimagen de la SEMNIM","doi":"10.1016/j.remn.2025.500159","DOIUrl":"10.1016/j.remn.2025.500159","url":null,"abstract":"<div><div>The increase in the prevalence of dementia in our clinical setting poses a diagnostic challenge for the Nuclear Medicine specialist. The aim of this study is to review the modifications in the procedure and to describe the usefulness of the use of brain PET with ¹⁸F-FDG in different clinical indications, both classic and emerging ones. The SEMNIM Neuroimaging working group has considered appropriate to update the procedures available in Spanish, in order to optimize the quality of this technique and the interpretation of its findings, both for the specialist in Nuclear Medicine and the rest of the professionals involved in the diagnosis and treatment of neurodegenerative diseases.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500159"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144563895","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"El efecto sinérgico de la resonancia magnética multiparamétrica y la imagen PET/TC con [18F]PSMA-1007 en el estudio de la recidiva del adenocarcinoma prostático localmente avanzado","authors":"D. Schmitt ,&nbsp;L. Schimmöller ,&nbsp;E. Novruzov ,&nbsp;J. Kirchner ,&nbsp;M. Boschheidgen ,&nbsp;E. Mamlins ,&nbsp;C. Antke ,&nbsp;Y. Mori ,&nbsp;G. Antoch ,&nbsp;F.L. Giesel","doi":"10.1016/j.remn.2025.500104","DOIUrl":"10.1016/j.remn.2025.500104","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500104"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557567","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Una comida sólida hipoalergénica para la gammagrafía de vaciado gástrico basada en la dieta mediterránea. «Una dieta para vaciarlos a todos»","authors":"P. Zaragoza-Ballester ,&nbsp;P. Sarandeses Fernández ,&nbsp;I. González Martín ,&nbsp;C. Martin-Arriscado Arroba ,&nbsp;M.I. Cabanillas Pérez ,&nbsp;X. Guarnizo Poma ,&nbsp;I. Castel de Lucas ,&nbsp;A. Galiana Morón ,&nbsp;D. Vega Pérez ,&nbsp;A.I. Romero Reina ,&nbsp;M.J. Tabuenca Mateo ,&nbsp;S. Ruiz Solís","doi":"10.1016/j.remn.2024.500093","DOIUrl":"10.1016/j.remn.2024.500093","url":null,"abstract":"<div><h3>Aim</h3><div>We aim to establish normal values and standardize a hypoallergenic and Mediterranean diet for gastric emptying scintigraphy (GES).</div></div><div><h3>Material and methods</h3><div>In a prospective cohort of healthy volunteers, we performed GES of a [⁹⁹Tc]TcDTPA²⁻ labelled hypoallergenic meal (egg, potato, rice and olive oil). Anterior and posterior images were simultaneously acquired at 0, 30, 60, 110, 120, 130, 180, 230, 240 and 250<!--> <!-->minutes. Cross-sectional analysis was performed between demographic data and gastric retention values. A score covariance analysis model was used to observer changes between measurements over time.</div></div><div><h3>Results</h3><div>50 participants (29 women) were included. Mean values and standard deviation (5-95th) for gastric retention percentages at 60, 120, 180, 240<!--> <!-->minutes were 51.40<!--> <!-->±<!--> <!-->8.63 (36.5-66.1), 21.66<!--> <!-->±<!--> <!-->9.40 (6.5-38.2), 7.58<!--> <!-->±<!--> <!-->5.77 (1.5-19.1) and 2.94<!--> <!-->±<!--> <!-->2.08 (1-7.3), respectively. Male participants had a significative faster gastric emptying compared to women in practically all the acquisitions. Male participants and smoker participants generated a significative decrease of gastric retention values in generalized linear model (male coefficient −4.818, 95%<!--> <!-->CI: −7.24 to −2.39, <em>P</em> <!-->&lt;<!--> <!-->.001; and smoker coefficient of −3.484, 95%<!--> <!-->CI: −6.29 to −0.67, <em>P</em> <!-->&lt;<!--> <!-->.05).</div></div><div><h3>Conclusion</h3><div>This study standardizes and establishes normal values for GES with the first hypoallergenic solid meal based on consensus recommendations and a Mediterranean diet; suitable for most patients with allergic or sensitive-conditions to other meal components.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500093"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557565","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Justificación e impacto del uso de la SPECT 123I-FP-CIT en el diagnóstico diferencial y manejo de los trastornos del movimiento (TM) en un hospital de referencia nacional","authors":"L. Canales Rodríguez ,&nbsp;M. Mitjavila Casanovas ,&nbsp;S. Ruiz Solís","doi":"10.1016/j.remn.2024.500092","DOIUrl":"10.1016/j.remn.2024.500092","url":null,"abstract":"<div><h3>Introduction</h3><div>Cerebral single photon emission computed tomography (SPECT) using ¹²³I-FP-CIT is a key tool in the differential diagnosis of movement disorders (MD), but its appropriate indication is essential to optimize resources and avoid unnecessary tests.</div></div><div><h3>Objective</h3><div>To evaluate the adequacy and impact of SPECT ¹²³I-FP-CIT in the diagnosis and management of MD according to clinical guidelines.</div></div><div><h3>Methodology</h3><div>Retrospective study involving 249 patients with suspected parkinsonism (PK) of uncertain origin. All underwent SPECT ¹²³I-FP-CIT and had a clinical follow-up of exceeding 12 months. Requests were classified based on their adherence to clinical guidelines. Variables analyzed included sex, age, justification for the request, management after SPECT, and final diagnosis.</div></div><div><h3>Results</h3><div>91.57% of the requests were appropriate, while 8.43% did not adhere to the guidelines. Diagnosis changed in 48.6% of cases and management in 70.68% after the scan, especially in inconclusive cases and initiation of therapy. General neurologists evaluated more cases and made more appropriate requests (96,3% vs 76,67%;p<!--> <!-->&lt;<!--> <!-->0,001). However, MD specialists, despite less appropriate use of the text, achieved a higher number of conclusive diagnoses in complex cases.</div></div><div><h3>Conclusion</h3><div>SPECT ¹²³I-FP-CIT has significant clinical impact when used in accordance with clinical guidelines, improving the diagnosis and management of MD. Unjustified scans reduce its utility. Collaboration between general neurologists and MD specialists is fundamental; the latter, although showing less adherence to guidelines in requesting the test, achieve a higher number of conclusive diagnoses in complex cases.</div></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"44 4","pages":"Article 500092"},"PeriodicalIF":1.6,"publicationDate":"2025-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144557699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}