Revista Espanola De Medicina Nuclear E Imagen Molecular最新文献

{"title":"Correlación entre los índices estandarizados SUVmáx de la PET/TC con [68Ga]Ga-PSMA-I&T pre-prostatectomía radical y los resultados histopatológicos finales: un análisis en profundidad","authors":"M.G. Arıkan ,&nbsp;S. Soyluoğlu ,&nbsp;Ü. Korkmaz ,&nbsp;E. Taştekin ,&nbsp;U. Elboğa ,&nbsp;E. Arda","doi":"10.1016/j.remn.2024.01.001","DOIUrl":"https://doi.org/10.1016/j.remn.2024.01.001","url":null,"abstract":"<div><h3>Objective</h3><p>To evaluate the predictive potential of the maximum standardized uptake value (SUVmax) value of intraprostatic tumors derived from preoperative [⁶⁸Ga]Ga-PSMA-I&amp;T PET/CT (SUVT), and its ratios to SUVmax in the liver (SUVTLR) and parotid gland (SUVTPR) with respect to histopathological findings.</p></div><div><h3>Materials and methods</h3><p>Data from patients who underwent radical prostatectomy (RP) for prostate cancer (PC) at our clinic between 2017-2020 were assessed. Patients with a secondary malignancy, a history of transurethral prostate resection, prior treatment for PC, or who received salvage RP were excluded. Whole-body images obtained using the same device, as per the guidelines, were reviewed by two nuclear medicine specialists with more than a decade of experience to reach a consensus for each lesion. The relationships between age, PSA, Prostate Volume, clinical T stage, biopsy International Society of Urological Pathology grade (ISUP), D’amico risk group, intraprostatic tumor volume (HPTV) identified in the final histopathological specimen review, HP-ISUP grade, seminal vesicle invasion (SVI), extracapsular invasion (ECI), positive surgical margine (PSM), SUVT, SUVTLR, and SUVTPR were analyzed.</p></div><div><h3>Results</h3><p>The mean age of the 64 included patients was 64.1±5.3 y-o. A statistically significant correlation was found between SUVT, SUVTLR, SUVTPR values, and histopathologic stage parameters, such as biopsy ISUP, D’amico Risk Classification, HP-ISUP, HPTV (<em>P</em>&lt;.05). PSMATV, SUVT, and SUVTLR were statistically significant predictors of extracapsular invasion, while PSA, PSMATV, and SUVTLR were significant predictors of SVI (<em>P</em>&lt;.05).</p></div><div><h3>Conclusion</h3><p>The standardized SUVT, SUVTLR, and SUVTPR values could be employed as noninvasive markers to assist in predicting postoperative histopathological findings, particularly ECI, SVI, and PSM.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 100-106"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140164067","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papel del radiofarmacéutico clínico en la seguridad del paciente durante los estudios de perfusión miocárdica de esfuerzo con vasodilatadores","authors":"C. Salgado-Garcia ,&nbsp;A. Moreno-Ballesteros ,&nbsp;P. Guardia-Jimena ,&nbsp;E. Sanchez-de-Mora ,&nbsp;A.C. Rebollo-Aguirre ,&nbsp;A. Ramirez-Navarro ,&nbsp;A. Santos-Bueno ,&nbsp;A. Jimenez-Heffernan","doi":"10.1016/j.remn.2023.11.005","DOIUrl":"10.1016/j.remn.2023.11.005","url":null,"abstract":"<div><h3>Aim</h3><p>To assess the radiopharmacist's role in a multidisciplinary team focused on the contraindications of regadenoson in order to ensure the safe use of pharmacologic vasodilator stress agents in patients undergoing SPECT-MPI.</p></div><div><h3>Methods</h3><p>We ambispectively studied its safe use in 1905 patients (54.1% female, mean age: 66.6<!--> <!-->±<!--> <!-->11.7 years, range: 20-95<!--> <!-->years). Sex, age, medical history, medications, drug allergies, and contraindications for stress testing were registered together with recommendations for the nuclear physician in charge.</p></div><div><h3>Results</h3><p>Detected contraindications and corresponding recommendations were as follows: risk factors for QTc interval prolongation 7.5% — measurement of QTc interval previously to test and monitor ECG; prior stroke or TIA 4.2% — consider carotid stenosis assessment; salicylates/sulfonamides allergy 3.1% — use ^99mTc-sestamibi; epilepsy or risk factors for seizures 2.4% — use of adenosine or reconsider test indication; systemic corticosteroid therapy for severe COPD 1.3% — reassessment of patient's condition; acute exacerbation of COPD 0.8% — defer test until acute episode is over; severe asthma 0.4% — do not perform test; methylxanthine ingestion 0.3% — avoid consumption previously; other 6.1% — evaluation of other contraindications. No contraindications were detected in 73.6% of patients. The test was cancelled due to absolute contraindications in 2.9% of the requests.</p></div><div><h3>Conclusions</h3><p>Working in a systematic way, the radiopharmacist was able to detect a high number of issues related to regadenoson, with one out of four patients presenting some clinical contraindication. The recommendations given by the radiopharmacist were well accepted by the nuclear physicians who changed their approach contributing to increase the safety of patients referred for MPI.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 84-90"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138986407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hallazgo casual mediante 18F-FDG PET/TC de una metástasis tiroidea causada por adenocarcinoma de recto","authors":"M. Mangas Losada,&nbsp;I. García Megías,&nbsp;X. Boulvard Chollet,&nbsp;L. Romero Robles,&nbsp;P. Garrastachu Zumarán,&nbsp;R. Ramírez Lasanta","doi":"10.1016/j.remn.2023.10.001","DOIUrl":"10.1016/j.remn.2023.10.001","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 115-116"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139293286","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Equipo multidisciplinar de cirugía radioguiada: Alternativa de cambio al paradigma actual","authors":"J. Ribera-Perianes ,&nbsp;M. Vega ,&nbsp;X. Cases Moreno ,&nbsp;J. Cordón ,&nbsp;J. Cortés Gracia ,&nbsp;P. Paredes ,&nbsp;N. Sánchez-Izquierdo ,&nbsp;A. Perissinotti ,&nbsp;D. Fuster Pelfort ,&nbsp;S. Vidal-Sicart","doi":"10.1016/j.remn.2023.12.001","DOIUrl":"10.1016/j.remn.2023.12.001","url":null,"abstract":"<div><h3>Introduction</h3><p>Given the constant increase in the healthcare demand for examinations related to radio-guided surgery (RGS), our hospital adopted new professional profiles in the RGS team, in order to partially reduce the time spent by nuclear medicine physicians on this task.</p></div><div><h3>Aim</h3><p>To analyze the process of incorporating the profiles of Superior Diagnostic Imaging Technician (TSID) and Sentinel Node Referent Nurse (ERGC), evaluating their deployment in the procedures linked to the technique.</p></div><div><h3>Material and methods</h3><p>Analysis of RGS activity during the period 2018-2022, focusing on pre-surgical and surgical procedures related to breast cancer (BC) and malignant melanoma (MM), as they are those pathologies on which the transfer of care competencies was concentrated. Chronological evolution of the competencies assumed by the different profiles during their integration into the RGS team.</p></div><div><h3>Results</h3><p>RGS's healthcare activity during the analyzed period experienced an increase of 109%. BC and MM were the pathologies that accounted for by far the greatest demand for care. The transfer of competencies in these two pathologies occurred in a progressive and staggered manner, with 74% (460/622) of the administration phase being carried out by the ERGC and 64% (333/519) of the surgeries by the TSID in 2022.</p></div><div><h3>Conclusions</h3><p>The creation of a multidisciplinary RGS team that includes different professional profiles (NM, ERGC and TSID) is an effective strategy to respond to the increase in the complexity and number of all procedures related to RGS.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 91-99"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391975","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Utilidad de la gammagrafía ósea de tres fases en la valoración de la agresividad de las lesiones extraóseas. Dos patrones gammagráficos diferentes","authors":"P. Zaragoza-Ballester,&nbsp;M.J. Tabuenca","doi":"10.1016/j.remn.2023.11.004","DOIUrl":"10.1016/j.remn.2023.11.004","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 121-123"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139021528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detección de neoplasia oculta en un paciente con dermatomiositis mediante la PET/TC con [18F]AlF-NOTA-FAPI-04 y con [18F]FDG","authors":"Z. Ye ,&nbsp;Y. Yao ,&nbsp;J. Yin ,&nbsp;Y. Kou ,&nbsp;M. Zhao ,&nbsp;Z. Cheng","doi":"10.1016/j.remn.2023.11.002","DOIUrl":"https://doi.org/10.1016/j.remn.2023.11.002","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 2","pages":"Pages 119-120"},"PeriodicalIF":1.2,"publicationDate":"2024-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140164070","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Tumor desmoplásico de células redondas pequeñas con afectación ovárica en PET/TC con [18F]FDG","authors":"Z. Zheng,&nbsp;P. Hu,&nbsp;Y. He,&nbsp;H. Shi","doi":"10.1016/j.remn.2023.08.006","DOIUrl":"10.1016/j.remn.2023.08.006","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 55-56"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139301081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Valor pronóstico de los parámetros hematológicos y los parámetros metabólicos de la PET/TC con [18F]FDG en el cáncer de cabeza y cuello","authors":"A. Baena García ,&nbsp;J.R. Infante de la Torre ,&nbsp;R. Barco Carbonero ,&nbsp;A. Martínez Esteve ,&nbsp;V. Vera Barragan ,&nbsp;J. Serrano Vicente ,&nbsp;P. Jiménez Granero ,&nbsp;A. Utrera Costero","doi":"10.1016/j.remn.2023.09.002","DOIUrl":"10.1016/j.remn.2023.09.002","url":null,"abstract":"<div><h3>Aim</h3><p>To determine the usefulness of neutrophil/lymphocyte (N/L) and platelet/lymphocyte (P/L) ratios as well as quantitative [¹⁸F]FDG PET/CT parameters as prognostic factors for overall survival (OS), cancer-specific survival (CSS) and progression-free survival (PFS) in patients with head and neck squamous cell carcinoma (HyN).</p></div><div><h3>Material and methods</h3><p>Sixty-six patients (56 men) diagnosed with HyN carcinoma were retrospectively assessed over an 8-year interval. Maximum SUV (SUVmax), metabolic tumour volume (MTV) and total lesion glycolysis (TLG) parameters were determined from the PET/CT study at diagnosis. After treatment with chemoradiotherapy, patient survival was assessed. The Cox regression model and the Kaplan-Meier method were used to analyse prognostic factors and survival curves.</p></div><div><h3>Results</h3><p>Median follow-up was 50.4<!--> <!-->months, with 39 recurrences-progressions and 39 deaths. In the univariate analysis, metabolic parameters, except SUVmax, were predictive factors for all three survivals and the two blood parameters were predictive for OS and EFS. TLG was the only predictive factor in the multivariate analysis. The three survival curves were significantly different for the metabolic parameters and the OS curve for the N/L ratio. Correlations were seen between N/L ratio, MTV and TLG. No correlations were demonstrated between P/L ratio and metabolic parameters.</p></div><div><h3>Conclusion</h3><p>The use of haematological and metabolic markers would allow to identify patients with a high risk of recurrences and poor survival and to individualise treatment by applying more aggressive therapies.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 31-38"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135809614","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Áreas de respeto graso que simulan metástasis hepáticas en PET/TC con 18F-FDG","authors":"P. Oliván-Sasot ,&nbsp;C. la Parra-Casado ,&nbsp;A.C. Orozco-Molano ,&nbsp;L. Camacho-Berne ,&nbsp;T. Peris-Conejero ,&nbsp;A. Tembl-Ferrairo","doi":"10.1016/j.remn.2023.09.005","DOIUrl":"10.1016/j.remn.2023.09.005","url":null,"abstract":"","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 59-60"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135810508","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Análisis visual y semicuantitativo del 6-[18F]FDOPA PET/TC en pacientes con tumores cerebrales ante la sospecha de recurrencia tumoral versus radionecrosis","authors":"M. Suárez-Piñera ,&nbsp;L. Rodriguez-Bel ,&nbsp;M. Alemany ,&nbsp;A. Pons-Escoda ,&nbsp;M. Pudis ,&nbsp;A. Coello ,&nbsp;G. Reynes ,&nbsp;N. Vidal ,&nbsp;M. Cortes-Romera ,&nbsp;M. Macia","doi":"10.1016/j.remn.2023.08.004","DOIUrl":"10.1016/j.remn.2023.08.004","url":null,"abstract":"<div><h3>Introduction</h3><p>Amino acid PET is a tool recommended by the main neuroimaging societies in the differential diagnosis between radionecrosis (RNC) and tumour recurrence (TR) in brain tumours, but its use in our country is still limited. The aim of this work is to present our experience with 6-[¹⁸F]FDOPA PET/CT (FDOPA) in brain tumours (primary and M1), comparing these results with other published results.</p></div><div><h3>Material and methods</h3><p>Retrospective study of 62 patients with suspected tumour recurrence (TR): 42 brain metastases (M1) and 20 primary, who underwent FDOPA. Images were analysed visually and semi-quantitatively, obtaining SUV_max and SUV_maxlesion/SUV_maxstriatum (L/S) and SUV_maxlesion/SUV_maxcortex (L/C) ratios. The diagnostic validity of PET was analysed and the best performing cut-off points were calculated. PET results were compared with clinical-radiological follow-up and/or histopathology.</p></div><div><h3>Results</h3><p>TR was identified in 49% of M1 and 76% of brain primaries. The best performing FDOPA interpretation was visual and semi-quantitative, with a sensitivity and specificity in primaries of 94% and 80% and in M1s of 96% and 72% respectively. The cut-off points with the best diagnostic performance were L/C1.44 in M1 and L/C1.55 in primaries. There are discrepant results with other published results.</p></div><div><h3>Conclusion</h3><p>FDOPA PET/CT is a useful tool in the differential diagnosis between recurrence and RNC in brain tumours. It is needed a standardization to contribute to homogenise FDOPA results a inter-centre level.</p></div>","PeriodicalId":48986,"journal":{"name":"Revista Espanola De Medicina Nuclear E Imagen Molecular","volume":"43 1","pages":"Pages 6-13"},"PeriodicalIF":1.2,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135606285","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}