Technology and Health Care最新文献

{"title":"A deep learning method for children's self-care problems classification using represent learning and focal loss.","authors":"Yang Yu, Yijia Tang, Xiaoyan Zhang, Tingyu Zhang, Jieqiong Liu","doi":"10.1177/09287329261440741","DOIUrl":"https://doi.org/10.1177/09287329261440741","url":null,"abstract":"<p><p>BackgroundAn accurate diagnosis of children's self-care problems significantly matters in the growth and development of children. However, various and extensive disorders make the self-care problems classification extremely complex and require much effort and time to solve.ObjectiveTo deal with the above challenge, a deep learning model is proposed to classify the children's self-care problems intelligently and precisely.MethodThe proposed deep learning model contains two sub-deep neural networks. The first sub-network employs a technology of representing learning named triplet loss. It aims to compress the dimensions of the feature of the children with self-care problems to extract the useful information and exclude the noise, in order to improve classification performance. The second sub-network utilizes a technology for handling the class imbalance problem called focal loss to further improve the classification accuracy.ResultThe experimental results show that the proposed deep learning model outperforms. The averages of accuracy, precision, recall, and F1 score can achieve 99.78%, 0.99, 0.99, and 0.99, respectively.ConclusionTo the best of our knowledge, the proposed method achieves state-of-the-art results. That can significantly support the rehabilitation and growth of children with self-care issues. Furthermore, this study also provides a demonstration and experience of the application of the deep learning model in the healthcare field.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"9287329261440741"},"PeriodicalIF":1.8,"publicationDate":"2026-04-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147786480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predicting one-year mortality risk in ICU patients with ischemic stroke using multi-algorithm machine learning and a nomogram.","authors":"Jian Huang, Yalin Dong, Xiaozhu Liu, Lijun Li","doi":"10.1177/09287329261423369","DOIUrl":"https://doi.org/10.1177/09287329261423369","url":null,"abstract":"<p><p><b>Introduction:</b> Ischemic stroke is a leading cause of mortality, and patients requiring intensive care unit (ICU) admission carry a guarded prognosis. We aimed to develop and validate a predictive model for estimating one-year mortality risk in ICU-admitted ischemic stroke patients.MethodsIn this retrospective cohort study, data from 1974 ischemic stroke patients were extracted from the MIMIC-IV database. Patients were randomly allocated into a training set (n = 1582) and a test set (n = 392) in an 8:2 ratio. Five machine learning algorithms (CART, RF, SVM, GBM, and NB) were employed for initial feature screening. Key predictors were subsequently integrated into a multivariate logistic regression model, which was visualized as a nomogram. The model's performance was evaluated using discrimination, calibration, and clinical utility metrics and was compared against established severity scores (SOFA, SAPS II, LODS, OASIS, GCS).ResultsThe final nomogram incorporated nine predictors: age, heart rate, weight, glucose, anion gap, calcium, alkaline phosphatase (ALP), red cell distribution width (RDW), and mean corpuscular hemoglobin concentration (MCHC). The model demonstrated an AUC of 0.739 (95% CI: 0.715-0.764) in the training set and 0.737 (95% CI: 0.688-0.786) in the test set. Calibration curves indicated good agreement between predictions and observations. Decision curve and clinical impact curve analyses confirmed the nomogram's favorable clinical net benefit, and it outperformed all comparator scoring systems in discriminatory ability.ConclusionsWe developed and validated a practical nomogram that effectively integrates key clinical variables to predict one-year mortality risk in ICU patients with ischemic stroke. This tool demonstrates robust performance and potential clinical utility for risk stratification.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"9287329261423369"},"PeriodicalIF":1.8,"publicationDate":"2026-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147595740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A review on Ag-Ta₂O₅ Bio-interfaces: Multifunctional coatings for antibacterial and biocompatible surgical tools.","authors":"Mohd Amirul, Rodianah Alias, Mohd Faizal Ali Akhbar, Muhammad Rizwan, Afifah Juri","doi":"10.1177/09287329261423370","DOIUrl":"https://doi.org/10.1177/09287329261423370","url":null,"abstract":"<p><p>BackgroundConventional surgical instruments made from Stainless steel (SS), Titanium (Ti), and Tantalum (Ta) are widely utilized because of their excellent corrosion resistance and strength-to-weight ratio. However, these materials lack antibacterial properties, which could increase the risk of surgical site infections. Recent advancements in antimicrobial and biocompatible coatings, particularly Ag-Ta₂O₅ (Silver-Tantalum Pentoxide), present better solutions for new surgical instrument design. Despite numerous studies published on this topic, a comprehensive review specifically addressing Ag-Ta₂O₅ coatings remains absent, resulting in fragmented information across the literature. Systematizing this information and consolidating the developments in this field are beneficial, and this is the motivation behind this review.ObjectiveFor these reasons, this review examines the development and applications of these advanced coatings, with a focus on their antimicrobial and biocompatible properties.MethodsWe critically examine the technological challenges, innovative coating methodologies, and the comparative advantages of Ag-Ta₂O₅ over traditional and hybrid coatings.ResultsFurthermore, this review identifies future research directions and proposes strategic collaborations among clinicians, engineers, policymakers, and materials scientists to expedite the clinical adoption of these coatings.ConclusionIt is envisioned that this review paper will serve as a valuable source of information for engineers, researchers, and clinicians to stay current with the latest developments in this area and for new researchers to initiate their exploration of coating technology.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"9287329261423370"},"PeriodicalIF":1.8,"publicationDate":"2026-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147516017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of transit time flow meter spike waveform on graft patency and its hemodynamic characteristics in coronary artery bypass grafting.","authors":"Minghui Wei, Zhou Zhao, Mengyao Duan, Gaoyang Li, Yanan Xu, Junyan Ge, Xiaoxiao Li, Ruoqi Zhao, Yue Feng, Boyan Mao","doi":"10.1177/09287329261432409","DOIUrl":"https://doi.org/10.1177/09287329261432409","url":null,"abstract":"<p><p>ObjectiveDuring coronary artery bypass grafting(CABG), surgeons commonly use transit time flow meter (TTFM) to determine the graft patency. This study is to explore the effect of a special \"spike waveform\" in CABG on graft patency and its hemodynamic environment.MethodsWe collected the data of 1154 patients undergoing CABG, including intraoperative TTFM waveform and coronary CTA at 1 week after surgery. 239 patients had 1-year follow-up CTA. We divided the grafts into spike and non-spike waveform groups, and assessed the patency of grafts. Additionally, we constructed an ideal model of CABG, we also calculated and extracted the hemodynamic parameters of the grafts.ResultsFor immediate patency, the occlusion rates of spike and non-spike waveforms of left internal mammary artery(LIMA) were 0 and 5.13%, those of saphenous vein graft(SVG) were 8.59% and 5.79%. As for medium-long term patency, the occlusion rates of spike and non-spike waveforms were 0 and 12.56% for LIMA, and 42.47% and 16.84% for SVG. Regarding hemodynamics, the relative residence time(RRT) and Max Oscillating shear index(MaxOSI) of the LIMA spike waveform were significantly higher than those of the non-spike waveform, and the mean OSI and MaxOSI of the SVG spike waveform were substantially higher than those of the non-spike waveform.ConclusionsSpike waveform slightly reduces the immediate patency of SVG and significantly reduces the medium-long term patency, while no effect on the patency of LIMA is found. In terms of hemodynamics, both LIMA and SVG with spike waveforms exhibit unfavorable hemodynamic conditions within the grafts.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"9287329261432409"},"PeriodicalIF":1.8,"publicationDate":"2026-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147488142","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Deciphering the mechanism and substance basis of Dingxiang Shidi Decoction for the treatment of chemotherapy-induced nausea and vomiting by integrating mass spectrometry, network pharmacology and molecular docking.","authors":"Min Zhan, Qian Wang, Jun Yan, Qiaoxuan Zhang, Liqiao Han, Zemin Wan, Shasha Li, Xianzhang Huang","doi":"10.1177/09287329251358624","DOIUrl":"10.1177/09287329251358624","url":null,"abstract":"<p><p>BackgroundChemotherapy-induced nausea and vomiting (CINV) remains a prevalent and debilitating side effect of cancer treatment with limited therapeutic options. Dingxiang Shidi Decoction (DXSD), a classical Chinese herbal formula, has demonstrated clinical efficacy in CINV management. However, its active components and mechanism of action require systematic investigation.ObjectiveThis study aims to elucidate the pharmacologically active constituents of DXSD and their anti-CINV mechanisms.MethodsWe employed advanced analytical techniques including UPLC-MS/MS and GC-MS to analyze the chemical components of DXSD. Network pharmacology techniques were applied to explore its pharmacological mechanisms. And molecular docking simulation was conducted to further refine the drug-target interaction.ResultsA total of 292 chemical compounds were identified in DXSD, comprising 165 water-soluble components, 56 volatile components, and 84 network database entries. By integrating 564 drug targets with 888 CINV disease targets, we identified 143 potential therapeutic targets. Further protein-protein interaction (PPI) network analysis revealed 12 key active ingredients and 13 key therapeutic targets. Enrichment analysis suggested that DXSD may reduce inflammation, modulate neurotransmitter stimulation in the gastrointestinal tract, and regulate cellular proliferation and differentiation. Notably, key active ingredients, predominantly aromatic compounds such as sabinene, (-)-α-cubebene, α-copaene, β-caryophyllene, aromandendrene, γ-muurolene, (-)-α-muurolene, α-phellandrene, α-terpinene, γ-terpinene, (+)-δ-cadinene, and Gomisin B, demonstrated significant binding affinity with multiple targets, particularly AKT1, BCL2, EGFR, MTOR, and STAT3.ConclusionsThis study reveals the active components and therapeutic mechanisms of DXSD against CINV, supporting its clinical application and demonstrating the potential of aromatherapy as an effective treatment strategy.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"51-62"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144643937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of virtual reality walking-in-place exercise and seated cycling on grip strength, lower limb strength, and five times sit-to-stand test in elderly individuals with dementia: A parallel randomized controlled trial.","authors":"SunWook Park, Seong-Gil Kim","doi":"10.1177/09287329251392398","DOIUrl":"10.1177/09287329251392398","url":null,"abstract":"<p><p>BackgroundThe prevalence of dementia is increasing among the aging global population. Innovative exercise interventions, such as virtual reality-based walking-in-place exercise (VR-WIPE) and seated cycling, are emerging for this population.ObjectiveThis study aimed to evaluate and compare the effects of these two exercise methods on physical function.MethodsThe study included 20 adult women (mean age: 78.9 ± 4.61 years) diagnosed with dementia and registered at a daycare center. Participants were randomly assigned to one of two groups according to intervention: experimental (n = 10); or control (n = 10). The experimental group received VR-WIPE, whereas the control group performed seated cycling. The primary outcome was the 5xSTS test, assessing functional mobility. Secondary outcomes included grip strength and lower limb strength.ResultsGrip strength increased significantly only in the seated cycling group (<i>p</i> < 0.05), with a small effect size (Cohen's d = 0.23). Both the cycling and VR-WIPE groups showed significant improvement in 5xSTS and lower limb strength (<i>p</i> < 0.05). Between-group comparisons revealed that the seated cycling group demonstrated significantly greater improvements in hip flexion and knee extension strength (Cohen's d = 1.36, 1.09, respectively), while ankle plantar flexion strength was significantly higher in the VR-WIPE group (<i>p</i> < 0.05, Cohen's d = 1.66).ConclusionsBoth seated cycling and VR-WIPE effectively improved lower limb strength and 5xSTS performance in older adult women with dementia. Seated cycling yielded greater improvements in hip and knee strength, whereas VR-WIPE was more effective in enhancing ankle plantar flexion strength.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"136-144"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145446183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Continuous health care evaluating for acute ischemic stroke patients with significant factor neural network relapse prediction model.","authors":"Lili Yu, Zhaoli Kong, Youwei Zhao","doi":"10.1177/09287329251392397","DOIUrl":"10.1177/09287329251392397","url":null,"abstract":"<p><p>The effect of continuous medical service intervention on health management for people who have suffered from Acute Ischemic Stroke (AIS) is an important issue in health care tracking. To pick out core aspects related to health, a relapse prediction model, evaluate the efficiency of continuous care and boost post-discharge results, a structured study is designed. After investigation and scientific verification, important signs and symptoms were chosen to set up a Significant Factors Neural Network Relapse Prediction Model (SFNNR) which aims to predict possible relapses based on previous patterns in medical data. The continuous care group was compared with the control group, and it turned out that participants in continuous care had significantly better results with fewer chances of having relapses and controlling chronic risks while displaying less psychological stress compared to the control group; furthermore, the continuous medical service showed great value on long-term management of AIS patients. The study points out that the integrated care approach should be taken more seriously as it can help healthcare staff predict the risk of relapse accurately so as to come up with personalized plans to control the relapse probability of the patients.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"229-245"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145514500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characteristics of thigh and shank affected side acceleration parameter during stroke hemiplegic gait.","authors":"Jeong-Woo Seo, Sangkwan Lee","doi":"10.1177/09287329251363425","DOIUrl":"10.1177/09287329251363425","url":null,"abstract":"<p><p>BackgroundDespite its clinical relevance, there is a relative lack of research examining flexibility and stability based on the acceleration or speed of localized limb segments, such as the shank and thigh.ObjectiveThis study aimed to evaluate gait characteristics based on acceleration in the thigh and shank to identify differences between the affected and unaffected sides in stroke hemiplegic patients.MethodForty individuals with stroke-induced hemiplegia were assessed during a 5-meter walk using a 3D motion analysis system and Inertial Measurement Units (IMUs). Spatial-temporal and acceleration parameters were calculated.ResultsSignificant differences were observed between the affected and unaffected sides in stance time, swing time, swing phase, and stance phase. In terms of acceleration, the mean acceleration in the anterior-posterior (AP) direction of the thigh and the mean value of the center of mass (CoM) in the AP direction differed significantly. These spatial-temporal findings were consistent with known characteristics of hemiplegic gait. A notable posterior shift of the thigh CoM on the affected side was identified, likely reflecting impaired propulsion and reduced stability.ConclusionThe posterior displacement of the thigh CoM on the affected side may represent a compensatory mechanism to maintain balance during gait. Clinically, this posterior CoM shift could serve as a meaningful indicator of hemiplegic gait and a potential target for rehabilitation interventions aimed at restoring gait symmetry and improving functional mobility.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"179-186"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144754921","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Identification of O-GlcNAcylation related genes and immune infiltration profile in ischemic stroke utilizing bioinformatics and machine learning.","authors":"Hongchao Liu, Zhihao Wei, Yajun Yang, Yu Zhang, Jiaqiong Li","doi":"10.1177/09287329251389496","DOIUrl":"10.1177/09287329251389496","url":null,"abstract":"<p><p>BackgroundIschemic stroke (IS) is a prevalent and serious neurological disorder, and inflammation and immune responses are crucial in the development of IS. O-GlcNAcylation is a form of post-translational modification that plays roles in numerous significant biological processes.ObjectiveThe major objective of the current study was to examine the involvement of O-GlcNAcylation associated genes in the pathogenesis of IS.MethodsWe downloaded two IS datasets from the GEO database, and subsequently the infiltration level of immune cells was quantified and compared. Differentially expressed O-GlcNAcylation genes were identified and machine learning algorithms were utilized to screen the hub genes. Subsequently, the IS samples were further classified based on hub genes through consensus clustering.ResultsOverall, nineteen O-GlcNAcylation related DEGs were identified. Through the machine learning algorithms, eight hub genes related to immune cell infiltration was identified. GSEA results showed that hub genes significantly correlated with immune system, RNA metabolism, and translation. Then two distinct subclusters mediated by O-GlcNAcylation were further defined, and functional analysis of cluster-specific DEGs demonstrated their participation in processes related to inflammation and immune response.ConclusionThe O-GlcNAcylation has a significant impact on the pathogenesis of IS, which is correlated with immunological response and metabolic activity. The findings of this research could serve as a valuable guide for exploring the molecular mechanisms of IS and offer insights into drug screening and immunotherapy for IS.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"90-110"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145410665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Acupotomy combined with oral pharmacotherapy for osteoarthritis: A systematic review and Bayesian network meta-analysis.","authors":"Zhengyao Zhang, Huiyi Li, Muyuan Zhai, Yiting Duan, Xiuzhi Zhang, Bo Liu, Dewei Zhao","doi":"10.1177/09287329251392395","DOIUrl":"10.1177/09287329251392395","url":null,"abstract":"<p><p>BackgroundOsteoarthritis (OA), a prevalent degenerative joint disease causing pain and disability, burdens global health. Acupotomy offers a minimally invasive alternative to surgery but faces limitations like variable efficacy. Combining acupotomy with oral pharmacotherapy (conventional or herbal medicine) may optimize outcomes through synergistic effects.ObjectiveTo systematically evaluate the efficacy and safety of acupotomy combined with oral medication for the treatment of osteoarthritis through a Bayesian network meta-analysis (NMA).MethodsThis study followed PRISMA-P guidelines. Randomised controlled trials (RCTs)were selected through 6 databases. Primary outcomes included overall effective rate, WOMAC score, VAS pain score, and adverse events.Results31 RCTs (3323 patients and 8 interventions) included. NMA revealed that Combinations outperformed other interventions in most comparisons. SUCRA represents the probability that an intervention ranks among the best. Notably, \"acupotomy + herbal medicine\" consistently ranked among the best across all three outcomes.ConclusionAcupotomy combined with oral medications demonstrated superior clinical efficacy and significant application potential. In clinical, acupotomy combined with conventional medications (e.g., NSAIDs) may be prioritised to alleviate acute symptoms, whereas acupotomy combined with herbal medicine shows more promising potential in long-term functional recovery. Treatment protocols should be tailored to individual patient conditions to maximise therapeutic outcomes.</p>","PeriodicalId":48978,"journal":{"name":"Technology and Health Care","volume":" ","pages":"154-166"},"PeriodicalIF":1.8,"publicationDate":"2026-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145524556","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}