Annual Review of Animal Biosciences最新文献_第2页

Reproductive and Metabolic Health Following Exposure to Environmental Chemicals: Mechanistic Insights from Mammalian Models. 暴露于环境化学品后的生殖和代谢健康：哺乳动物模型的机理研究。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-11-12 DOI: 10.1146/annurev-animal-111523-102259

Michelle Bellingham, Neil P Evans, Richard G Lea, Vasantha Padmanabhan, Kevin D Sinclair

{"title":"Reproductive and Metabolic Health Following Exposure to Environmental Chemicals: Mechanistic Insights from Mammalian Models.","authors":"Michelle Bellingham, Neil P Evans, Richard G Lea, Vasantha Padmanabhan, Kevin D Sinclair","doi":"10.1146/annurev-animal-111523-102259","DOIUrl":"https://doi.org/10.1146/annurev-animal-111523-102259","url":null,"abstract":"The decline in human reproductive and metabolic health over the past 50 years is associated with exposure to complex mixtures of anthropogenic environmental chemicals (ECs). Real-life EC exposure has varied over time and differs across geographical locations. Health-related issues include declining sperm quality, advanced puberty onset, premature ovarian insufficiency, cancer, obesity, and metabolic syndrome. Prospective animal studies with individual and limited EC mixtures support these observations and provide a means to investigate underlying physiological and molecular mechanisms. The greatest impacts of EC exposure are through programming of the developing embryo and/or fetus, with additional placental effects reported in eutherian mammals. Single-chemical effects and mechanistic studies, including transgenerational epigenetic inheritance, have been undertaken in rodents. Important translational models of human exposure are provided by companion animals, due to a shared environment, and sheep exposed to anthropogenic chemical mixtures present in pastures treated with sewage sludge (biosolids). Future animal research should prioritize EC mixtures that extend beyond a single developmental stage and/or generation. This would provide a more representative platform to investigate genetic and underlying mechanisms that explain sexually dimorphic and individual effects that could facilitate mitigation strategies.","PeriodicalId":48953,"journal":{"name":"Annual Review of Animal Biosciences","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631077","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Ruminating on Bovine Implantation: Its Importance in Fertility, Food Production, Conservation, and Health. 刍议牛的植入：其在繁殖力、食品生产、保护和健康方面的重要性。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-11-12 DOI: 10.1146/annurev-animal-111523-102403

Olga Amelkina, Samantha Gardner, Jessica C Edge, Zenab Butt, Haidee Tinning, Niamh Forde

{"title":"Ruminating on Bovine Implantation: Its Importance in Fertility, Food Production, Conservation, and Health.","authors":"Olga Amelkina, Samantha Gardner, Jessica C Edge, Zenab Butt, Haidee Tinning, Niamh Forde","doi":"10.1146/annurev-animal-111523-102403","DOIUrl":"https://doi.org/10.1146/annurev-animal-111523-102403","url":null,"abstract":"Implantation in cattle is a key developmental checkpoint for pregnancy success. It involves careful spatiotemporal changes to the transcriptional landscape of the endometrium, with the heterogeneous nature of the endometrium increasing the complexity of understanding of the mechanism involved. Implantation is impacted by the developmental competency of the embryo, use of assisted reproductive technologies, and the environment in which this process occurs. We identify the factors that most impact the implantation process in cattle and highlight how it differs with that in other placental mammals. We propose the major areas that lack evidence are the mechanism(s) by which implantation itself occurs and how different stressors alter this process. Our understanding is hindered by a lack of appropriate in vitro models; however, development of novel 3D tools and available data sets will further elucidate the implantation process. Perhaps more importantly, this will develop methods to mitigate against these stressors to improve implantation success and offspring health.","PeriodicalId":48953,"journal":{"name":"Annual Review of Animal Biosciences","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Progress Toward Genetic Rescue of the Northern White Rhinoceros (Ceratotherium simum cottoni). 拯救北方白犀牛（Ceratotherium simum cottoni）基因的进展。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-11-12 DOI: 10.1146/annurev-animal-111523-102158

Marisa L Korody, Thomas B Hildebrandt

{"title":"Progress Toward Genetic Rescue of the Northern White Rhinoceros (Ceratotherium simum cottoni).","authors":"Marisa L Korody, Thomas B Hildebrandt","doi":"10.1146/annurev-animal-111523-102158","DOIUrl":"https://doi.org/10.1146/annurev-animal-111523-102158","url":null,"abstract":"The northern white rhinoceros (NWR) is functionally extinct, with only two nonreproductive females remaining. However, because of the foresight of scientists, cryopreserved cells and reproductive tissues may aid in the recovery of this species. An ambitious program of natural and artificial gamete and in vitro embryo generation was first outlined in 2015, and many of the proposed steps have been achieved. Multiple induced pluripotent stem cell lines have been established, primordial germ cell-like cells have been generated, oocytes have been collected from the remaining females, blastocysts have been cryopreserved, and the closely related southern white rhinoceros (SWR) is being established as a surrogate. Recently, the first successful embryo transfer in SWR demonstrated that embryos can be generated by in vitro fertilization and cryopreserved. We explore progress to date in using advanced cellular technologies to save the NWR and highlight the necessary next steps to ensure a viable population for reintroduction. We roll out a holistic rescue approach for a charismatic megavertebrate that includes the most advanced cellular technologies, which can provide a blueprint for other critically endangered mammals. We also provide a detailed discussion of the remaining questions in such an upgraded conservation program.","PeriodicalId":48953,"journal":{"name":"Annual Review of Animal Biosciences","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2024-11-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142631074","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Parasites in a Changing World: Troublesome or in Trouble? 寄生虫在不断变化的世界中：麻烦还是麻烦？

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-11-11 DOI: 10.1146/annurev-animal-111523-102039

Chelsea L Wood

引用次数: 0

Integrated Genomic Approaches to Characterize and Mitigate Heat Stress in Poultry. 表征和缓解家禽热应激的综合基因组方法。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-10-30 DOI: 10.1146/annurev-animal-111523-102021

Carl J Schmidt, Susan J Lamont

引用次数: 0

Translational Relevance and Future Integration of the Oncopig Cancer Model in Preclinical Applications. Oncopig 癌症模型在临床前应用中的转化意义和未来整合。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-10-17 DOI: 10.1146/annurev-animal-111523-102125

Lobna Elkhadragy, Ron C Gaba, Matthew M Niemeyer, Lawrence B Schook, Kyle M Schachtschneider

{"title":"Translational Relevance and Future Integration of the Oncopig Cancer Model in Preclinical Applications.","authors":"Lobna Elkhadragy, Ron C Gaba, Matthew M Niemeyer, Lawrence B Schook, Kyle M Schachtschneider","doi":"10.1146/annurev-animal-111523-102125","DOIUrl":"https://doi.org/10.1146/annurev-animal-111523-102125","url":null,"abstract":"Porcine cancer models offer a valuable platform for evaluating interventions such as devices, surgeries, and locoregional therapies, which are often challenging to test in mouse models. In addition to size and anatomical similarities with humans, pigs share greater similarities in genetics, immunity, drug metabolism, and metabolic rate with humans as compared to mouse models, increasing their translational relevance. This review focuses on the Oncopig Cancer Model, a genetically engineered porcine model designed to recapitulate human cancer. Harboring a transgenic cassette that expresses oncogenic mutant KRAS and TP53 under control of a Cre-Lox system, the Oncopig allows temporal and spatial control of tumor induction. Its versatility has enabled the development of diverse cancer models including liver, pancreatic, lung, and bladder cancer. Serving as a clinically relevant model for human cancer, the Oncopig addresses unmet clinical needs and holds immense promise for advancing preclinical cancer research and therapeutic development.","PeriodicalId":48953,"journal":{"name":"Annual Review of Animal Biosciences","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2024-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

An Evolutionary Perspective on Dog Behavioral Genetics. 狗行为遗传学的进化视角。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-10-16 DOI: 10.1146/annurev-animal-111523-101954

Kathryn A Lord, Frances L Chen, Elinor K Karlsson

引用次数: 0

No More Extinctions: Recovering Australia's Biodiversity. 不再灭绝：恢复澳大利亚的生物多样性。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-10-01 DOI: 10.1146/annurev-animal-111523-102004

John C Z Woinarski, Stephen T Garnett, Sarah M Legge

引用次数: 0

Improving Nutrition Security in Low- and Middle-Income Countries and the Role of Animal-Source Foods. 改善中低收入国家的营养安全和动物源食品的作用》。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-09-24 DOI: 10.1146/annurev-animal-111523-102149

Fevi Rose Paro, Roselyn Davour, Daniel Acosta, Karah Mechlowitz, Chhavi Tiwari, Sarah L McKune

{"title":"Improving Nutrition Security in Low- and Middle-Income Countries and the Role of Animal-Source Foods.","authors":"Fevi Rose Paro, Roselyn Davour, Daniel Acosta, Karah Mechlowitz, Chhavi Tiwari, Sarah L McKune","doi":"10.1146/annurev-animal-111523-102149","DOIUrl":"https://doi.org/10.1146/annurev-animal-111523-102149","url":null,"abstract":"Nutrition security is challenging in regions where resources are limited and food production is naturally constrained. In low- and middle-income countries (LMICs), undernutrition is high for many reasons, including lack of nutritional diversity and low high-quality protein content. Interest in the role of animal-source food (ASF) in reducing nutrition insecurity is increasing, as evidence from LMICs suggests that consumption of ASF is strongly associated with reduction in stunting, improved diet quality, and overall nutrition, particularly in early stages of life. We review the strengths and limitations of ASF consumption in terms of accessibility, safety, and nutritional benefits compared to non-ASF sources. We present a critical discussion on existing barriers to ASF consumption and its future directions in LMICs. Understanding the role of ASF in improving nutrition security in LMICs is crucial to optimizing public health, designing appropriate interventions, and implementing effective policy in resource-poor settings.","PeriodicalId":48953,"journal":{"name":"Annual Review of Animal Biosciences","volume":" ","pages":""},"PeriodicalIF":8.7,"publicationDate":"2024-09-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142330580","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"农林科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pregnancy Establishment and Diagnosis in Livestock. 家畜的妊娠确定和诊断。

IF 8.7 1区农林科学

Annual Review of Animal Biosciences Pub Date : 2024-08-21 DOI: 10.1146/annurev-animal-021022-032214

Troy L Ott, Ahmed Tibary, Muhammad Waqas, Rodney Geisert, Julio Giordano

引用次数: 0