Konstantin Warneke, Ewan Thomas, Anthony J Blazevich, José Afonso, David G Behm, Paulo H Marchetti, Gabriel S Trajano, Masatoshi Nakamura, Francisco Ayala, Stefano Longo, Nicolas Babault, Sandro R Freitas, Pablo B Costa, Andreas Konrad, Antoine Nordez, Arnold Nelson, Astrid Zech, Anthony D Kay, Olyvia Donti, Jan Wilke
{"title":"Practical recommendations on stretching exercise: A Delphi consensus statement of international research experts.","authors":"Konstantin Warneke, Ewan Thomas, Anthony J Blazevich, José Afonso, David G Behm, Paulo H Marchetti, Gabriel S Trajano, Masatoshi Nakamura, Francisco Ayala, Stefano Longo, Nicolas Babault, Sandro R Freitas, Pablo B Costa, Andreas Konrad, Antoine Nordez, Arnold Nelson, Astrid Zech, Anthony D Kay, Olyvia Donti, Jan Wilke","doi":"10.1016/j.jshs.2025.101067","DOIUrl":"10.1016/j.jshs.2025.101067","url":null,"abstract":"<p><strong>Background: </strong>Stretching has wide appeal, but there seems to exist some mismatch between its purported applications and what the evidence shows. There is compelling evidence for some stretching applications, but for others, the evidence seems heterogeneous or unsupportive. The discrepancies even affect some systematic reviews, possibly due to heterogeneous eligibility criteria and search strategies. This consensus paper seeks to unify the divergent findings on stretching and its implications for both athletic performance and clinical practices by delivering evidence-based recommendations.</p><p><strong>Methods: </strong>A panel of 20 experts with a blend of practical experience and scholarly knowledge was assembled. The panel meticulously reviewed existing systematic reviews, defined key terminologies (e.g., consensus definitions for different stretching modes), and crafted guidelines using a Delphi consensus approach (minimum required agreement: 80%). The analysis focused on 8 topics, including stretching's acute and chronic (long-term) effects on range of motion, strength performance, muscle hypertrophy, stiffness, injury prevention, muscle recovery, posture correction, and cardiovascular health.</p><p><strong>Results: </strong>There was consensus that chronic and acute stretching (a) improves range of motion (although alternatives exist) and (b) reduces muscle stiffness (which may not always be desirable); the panel also agreed that chronic stretching (c) may promote vascular health, but more research is warranted. In contrast, consensus was found that stretch training does not (a) contribute substantively to muscle growth, (b) serve as an all-encompassing injury prevention strategy, (c) improve posture, or (d) acutely enhance post-exercise recovery.</p><p><strong>Conclusion: </strong>These recommendations provide guidance for athletes and practitioners, highlighting research gaps that should be addressed to more comprehensively understand the full scope of stretching effects.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101067"},"PeriodicalIF":10.3,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12305623/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Charles J Rayner, David B Bartlett, Sophie K Allen, Tyler Wooldridge, Tadd Seymour, Sunny Sunshine, Julie Hunt, David King, Izhar Bagwan, Javed Sultan, Shaun R Preston, Adam E Frampton, Nicola E Annels, Nima Abbassi-Ghadi
{"title":"Prehabilitation during neoadjuvant chemotherapy results in an enhanced immune response in esophageal adenocarcinoma tumors: A randomized controlled trial.","authors":"Charles J Rayner, David B Bartlett, Sophie K Allen, Tyler Wooldridge, Tadd Seymour, Sunny Sunshine, Julie Hunt, David King, Izhar Bagwan, Javed Sultan, Shaun R Preston, Adam E Frampton, Nicola E Annels, Nima Abbassi-Ghadi","doi":"10.1016/j.jshs.2025.101063","DOIUrl":"10.1016/j.jshs.2025.101063","url":null,"abstract":"<p><strong>Background: </strong>For patients with locally advanced esophagogastric cancer, the standard of care in the UK is neoadjuvant chemotherapy (NAC) followed by surgery. Prehabilitation exercise training can improve physiological function and fitness. If such improvements translate to increased immune infiltration of tumors, exercise could be prescribed as an immune adjuvant during NAC and potentially improve clinical outcomes. As such, we aimed to determine whether prehabilitation increased tumor infiltrating lymphocytes (TILs).</p><p><strong>Methods: </strong>We assessed 22 patients with locally advanced esophageal cancer on a randomized control trial comparing 16 weeks of low-to-moderate intensity twice weekly supervised and thrice weekly home-based exercise (Prehab: n = 11) to no prehabilitation (Control: n = 11). Our primary outcome was to compare tumor-immune responses between Controls and Prehab. We compared formalin-fixed paraffin-embedded tumors by high-resolution multispectral immunohistochemistry (mIHC) and NanoString spatial transcriptomics. Secondarily, we determined relationships between changes in fitness to the exercise training and tumor-immune measures. Specifically, we assessed percentage changes in peak cardiorespiratory fitness as assessed by peak oxygen uptake (V̇O<sub>2peak</sub>) before NAC (Baseline) and after 8 weeks of NAC (Post-NAC), and changes between Baseline and following 8 weeks of NAC recovery before surgery (Pre-surgery) and correlated changes in fitness with tumor-immune responses. Finally, as an exploratory aim, we assessed clinical outcomes between groups, including survival, therapy tolerance, and tumor regrading.</p><p><strong>Results: </strong>We observed that Prehab had significantly more CD8+ lymphocytes in their tumors (mean difference (diff.) = 1.79, 95% confidence interval (95%CI): 0.76‒2.82, p < 0.001) and their stroma (mean diff. = 1.59, 95%CI: 0.66‒2.52, p < 0.001) than the Controls. When normalized to total numbers of TILs, Prehab had higher levels of CD56+ natural killer (NK) cells (median diff. = 0.87, 95%CI: 0.25‒2.18), p = 0.0274), consisting primarily of CD56<sup>dim</sup> NK cells (median diff. = 0.48, 95%CI: 0.03‒2.53), p = 0.0464). Evaluation of the presence and localization of tumor-associated tertiary lymphoid structures (TLS) in the esophageal tumors revealed that most TLS were in the peritumoral regions. Prehab had a higher TLS cell density (cells/mm<sup>2</sup>; median diff. = 18,959, 95%CI: 13,518‒22,635), p < 0.001) and more clearly defined germinal centers indicative of mature TLS visually. We observed that Prehab maintained their V̇O<sub>2peak</sub> during NAC while the Controls' V̇O<sub>2peak</sub> reduced by 9.0% ± 10.2% (mean ± SD) (Post-NAC: p = 0.018). Pre-surgery, Prehab V̇O<sub>2peak</sub> was a clinically meaningful 3.27 ± 1.31 mL/kg/min higher than Controls (p = 0.022). Between Baseline and Post-NAC, where the Prehab maintained V̇O<sub>2peak</sub> better than Contr","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101063"},"PeriodicalIF":10.3,"publicationDate":"2025-06-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12451371/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Martina E Schmidt, Siri Goldschmidt, Charlotte Kreutz, Jana Müller, Andreas Schneeweiss, Anne M May, Friederike Rosenberger, Joachim Wiskemann, Karen Steindorf
{"title":"Effects of aerobic or resistance exercise during neoadjuvant chemotherapy on tumor response and therapy completion in women with breast cancer: The randomized controlled BENEFIT trial.","authors":"Martina E Schmidt, Siri Goldschmidt, Charlotte Kreutz, Jana Müller, Andreas Schneeweiss, Anne M May, Friederike Rosenberger, Joachim Wiskemann, Karen Steindorf","doi":"10.1016/j.jshs.2025.101064","DOIUrl":"10.1016/j.jshs.2025.101064","url":null,"abstract":"<p><strong>Background: </strong>The potential of exercise as a concurrent therapy for actively treated primary tumors has been suggested by emerging preclinical and observational studies. However, clinical trials regarding this question are scarce. Therefore, we conducted a randomized controlled trial investigating the effects of aerobic or resistance exercise concomitant to neoadjuvant chemotherapy (NACT) on tumor size.</p><p><strong>Methods: </strong>In the BENEFIT study (German title: Bewegung bei neoadjuvanter chemotherapie zur verbesserung der fitness), patients with breast cancer scheduled for NACT were randomly assigned to supervised resistance training (RT, n = 60) or aerobic training (AT, n = 60) twice weekly during NACT or to a waitlist control group (WCG, n = 60). The primary outcome, \"change in tumor size\", as well as the secondary clinical outcomes pathologic complete response (pCR), type of surgery (breast conserving/mastectomy), axillary lymph node dissection (ALND, yes/no), premature discontinuation of chemotherapy (yes/no), and relative dose intensity (RDI) were derived from clinical records. Due to the highly skewed distribution, the primary outcome was categorized. Multiple (ordinal) logistic regression analyses were performed.</p><p><strong>Results: </strong>Overall, there was no significant difference in post-intervention tumor size between RT or AT and WCG. However, there was a significant effect modification by hormone receptor (HR) status (p<sub>interaction</sub> = 0.030). Among patients with HR+ tumors, results suggest a beneficial effect of AT on tumor shrinkage (odds ratio (OR) = 2.37, 95% confidence interval (95%CI): 0.97‒5.78), on pCR (OR = 3.21, 95%CI: 0.97‒10.61); and on ALND (OR = 3.76, 95%CI: 0.78‒18.06) compared to WCG. The effects of RT were slightly less pronounced. For HR-subtypes, beneficial effects on RDI were found for AT (OR = 3.71, 95%CI: 1.20‒11.50) and similarly for RT (OR = 2.58, 95%CI: 0.88‒7.59). Both AT and RT had favorable effects on premature discontinuation of chemotherapy (OR (no vs. yes) = 2.34, 95%CI: 1.10‒5.06), irrespective of tumor receptor status.</p><p><strong>Conclusion: </strong>While there was no significant effect on the primary outcome in the overall group, aerobic and resistance exercise concomitant to NACT seem to beneficially affect tumor shrinkage and pCR, reduce the need for ALND among patients with HR+ breast cancers, and prevent low RDI among patients with HR- breast cancers. These results warrant confirmation in further trials.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101064"},"PeriodicalIF":10.3,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12395146/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Isa H Mast,Elske C Gootjes,Heidi Rütten,Mariska D den Hartogh,Calvin G Brouwer,Iris D Nagtegaal,Rachel S van der Post,Maria T E Hopman,Baukje van den Heuvel,Camiel Rosman,Johannes H W de Wilt,Bastiaan R Klarenbeek,Laurien M Buffart
{"title":"Feasibility and clinical potential of exercise interventions during neoadjuvant chemoradiotherapy in patients with esophageal and rectal cancer.","authors":"Isa H Mast,Elske C Gootjes,Heidi Rütten,Mariska D den Hartogh,Calvin G Brouwer,Iris D Nagtegaal,Rachel S van der Post,Maria T E Hopman,Baukje van den Heuvel,Camiel Rosman,Johannes H W de Wilt,Bastiaan R Klarenbeek,Laurien M Buffart","doi":"10.1016/j.jshs.2025.101060","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101060","url":null,"abstract":"BACKGROUNDExercise during neoadjuvant chemoradiotherapy (NCRT) has potential to mitigate treatment-related declines in physical fitness, and to improve clinical outcomes, including toxicity and tumor response. However, optimal frequency and timing of exercise remains to be determined. Therefore, this pilot trial aimed to assess feasibility of 2 different exercise interventions during NCRT in patients with esophageal and rectal cancer and to evaluate potential clinical effects.METHODSPatients were randomized into 1 of 3 study arms during NCRT: (a) 30-min aerobic exercise in-hospital within 1 h prior to each radiotherapy fraction (ExPR), (b) two 60-min supervised combined aerobic and resistance exercise sessions per week (AE+RE), and (c) usual care (UC). Feasibility was assessed by examining participation rate and exercise adherence. Intervention effects on physical fitness, health-related quality of life, treatment-related toxicity, and tumor response in patients with esophageal cancer were explored using regression analyses and 85% confidence intervals (85%CI).RESULTSThirty-seven patients with esophageal cancer (participation rate: 45%) and 2 patients with rectal cancer (participation rate: 14%) were included. Median session attendance was 98% (interquartile range (IQR): 96-100) in the ExPR and 78% (IQR: 33-100) in the AE+RE group. We found clinically relevant benefits of exercise on maximal oxygen uptake (VO2max)(ExPR: β = 9.7 mL/kg/min, 85%CI: 6.9-12.6; AE+RE: β = 5.6 mL/kg/min, 85%CI: 2.6-8.5) and treatment-related toxicity (ExPR: β = -2.8, 85%CI: -5.4 to -0.2; AE+RE: β = -2.6, 85%CI: -5.3 to 0.0). Additionally, good tumor response was found in 70% in AE+RE and ExPR vs. 55% in UC (OR = 1.9, 85%CI: 0.5-7.7).CONCLUSIONStarting prehabilitation during NCRT is feasible, can increase starting fitness of traditional pre-surgical programs, and has potential to improve clinical outcomes.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"29 1","pages":"101060"},"PeriodicalIF":11.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145920","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Prolonged passive vibration of Achilles and patellar tendons decreases effort perception during subsequent cycling tasks.","authors":"Florian Marchand,Benjamin Pageaux,Nicolas Forestier,Florian Monjo","doi":"10.1016/j.jshs.2025.101061","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101061","url":null,"abstract":"BACKGROUNDThe perception of effort is a key determinant of endurance performance and a barrier to physical activity in inactive populations. From a neurophysiological viewpoint, effort perception is thought to arise from the brain processing of an efference copy of the motor command in sensory areas. However, recent research suggests that feedback from muscle spindles plays a significant role in this perception. In this study, tendon vibration protocols were employed to attenuate sensory feedback during subsequent cycling exercises. The aim was to assess whether vibration would increase cycling power output, muscle activation, and heart rate at fixed perceived effort intensities.METHODSFifteen healthy young participants completed 2 experimental visits (vibration and sham). In each visit, participants performed two 3-min cycling bouts, 1 at a moderate perceived effort intensity and 1 at a strong perceived effort intensity, before (pre) and after (post) an actual or a sham vibration protocol. Vibration was applied bilaterally on the patellar and Achilles tendons for 10 min. Power output, heart rate, and vastus lateralis electromyography (VL EMG) were recorded and averaged for each bout. Absolute values as well as relative change (%) between pre and post conditions were compared across sham and vibration conditions.RESULTSAt moderate perceived effort, power output, heart rate, and VL EMG increased post-vibration compared to pre-vibration (p < 0.05), while no difference was observed in the sham condition. At strong perceived effort, power output and VL EMG decreased post-sham (p < 0.05) but remained unchanged post-vibration. Moreover, the relative change between pre and post conditions was significantly higher in the vibration conditions compared to the sham condition for all variables.CONCLUSIONThis study shows that tendon vibration reduces effort perception during subsequent cycling bouts. This effect is likely a consequence of vibration-induced reduction in muscle spindle reafferent signaling to the brain, but this mechanism remains to be further elucidated. From an applied perspective, these findings highlight tendon vibration as a promising tool for enhancing physical activity engagement.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"51 1","pages":"101061"},"PeriodicalIF":11.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Reverse-normal immunopurification: An effective approach for purifying recombinant erythropoietin from its analogues in doping analysis.","authors":"Sen He,Die Wu,Chengshuai Niu,Xinchao Liu,Jie Zhang,Liangzhi Xie,Laurent Martin,Kaifeng Liu,Xinmiao Zhou,Lisi Zhang","doi":"10.1016/j.jshs.2025.101062","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101062","url":null,"abstract":"BACKGROUNDRecombinant erythropoietin (rEPO) is commonly used in therapy but may be abused in sports to enhance endurance. In doping analysis, rEPO can be detected in human urine or blood samples at picogram (pg) levels based on its slightly higher molecular weight (MW) than that of endogenous EPO using western blotting (WB). However, a type of variant erythropoietin (VAR-EPO) encoded by the EPO c.577del variant has a similar MW to rEPO, and these 2 molecules cannot be distinguished using conventional analytical methods. A fit-for-purpose method needs to be developed immediately.METHODSIn this study, we introduced a reverse-normal immunopurification technique for sample pretreatment to remove VAR-EPO from samples to eliminate its interference with rEPO detection. Firstly, a rabbit monoclonal antibody (mAb) that can specifically recognize trace amounts of VAR-EPO with high affinity was generated. Then, using this antibody to enrich VAR-EPO, we developed reverse-normal immunopurification coupled with WB on the purpose of analyzing rEPO in urine and serum samples Next, the method was fully validated and evaluated using blank samples, spiked samples and rEPO excreted samples. Finally, the identification criteria of rEPO was established.RESULTSA specific anti-VAR mAb with high affinity was developed. Using it, we developed the doping analytical method for rEPO. Our method effectively detects and removes VAR-EPO, enabling accurate rEPO detection.CONCLUSIONA method has already been applied for rEPO confirmation in routine doping analyses.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"26 1","pages":"101062"},"PeriodicalIF":11.7,"publicationDate":"2025-05-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144145956","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mette Yun Johansen,Cody Garett Durrer,Nanna Skytt Pilmark,Grit Elster Legaard,Kristian Karstoft,Katrine Bagge Hansen,Christopher Scott MacDonald,Thomas Peter Almdal,Jakob Bue Bjorner,Nicolai J Wewer Albrechtsen,Allan Arthur Vaag,Robin Christensen,Bente Klarlund Pedersen,Mathias Ried-Larsen
{"title":"Six-year follow-up of glycemic control and cardiovascular risk factors after a one-year intensive lifestyle intervention in type 2 diabetes: An extension of the randomized U-TURN trial.","authors":"Mette Yun Johansen,Cody Garett Durrer,Nanna Skytt Pilmark,Grit Elster Legaard,Kristian Karstoft,Katrine Bagge Hansen,Christopher Scott MacDonald,Thomas Peter Almdal,Jakob Bue Bjorner,Nicolai J Wewer Albrechtsen,Allan Arthur Vaag,Robin Christensen,Bente Klarlund Pedersen,Mathias Ried-Larsen","doi":"10.1016/j.jshs.2025.101059","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101059","url":null,"abstract":"PURPOSEThis study aimed to describe the effects of a 1-year lifestyle intervention on hemoglobin A1c (HbA1c) and cardiovascular risk factors 5 years after cessation of the lifestyle intervention in persons with type 2 diabetes (T2D).METHODSFrom April 2015 to August 2016, 98 persons with T2D (duration < 10 years) were randomly allocated (2:1, stratified by sex) to a 1-year lifestyle intervention group (INT) (n = 64) or a standard care group (StC) (n = 34). All participants received standard care with blinded, target-driven medical therapy. INT included up to 5-6 weekly supervised aerobic and strength training sessions and dietary plans targeting a body mass index ≤ 25 kg/m². No intervention was given during the follow-up period. Forty-nine (77%) and 19 (56%) participants in INT and StC attended the 6-year follow-up. Based on the original intention-to-treat population, the primary outcome was the change in HbA1c from baseline to 6-year follow-up. Secondary outcomes included weight, Low density lipoprotein (LDL) cholesterol, blood pressure (BP), and cardiorespiratory fitness.RESULTSNinety-eight participants (mean age 54.6 years; 46% women; mean baseline Hemoglobin A1c (HbA1c): 49.8 mmol/mol) were analyzed. HbA1c changed 6% and 13% in the INT and StC from baseline to 6-year follow-up (between group difference: -6% (95%CI: -14 to 3); p = 0.18). While no differences were observed for most secondary outcomes, the diastolic BP decreased 6.0 (95%CI: 2.1 to 9.8) mmHg more in the StC compared to INT.CONCLUSIONThe sustained effect of the lifestyle intervention on glycemic control and cardiovascular risk factors was marginal, and it was surprisingly associated with inferior diastolic BP regulation.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"45 1","pages":"101059"},"PeriodicalIF":11.7,"publicationDate":"2025-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136812","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Christina L Master,Mitchell Scheiman,Olivia E Podolak,Matthew F Grady,David Howell
{"title":"Metrics of concussion-related vision disorders among children and adolescents with persisting post-concussive symptoms using an objective eye tracking device.","authors":"Christina L Master,Mitchell Scheiman,Olivia E Podolak,Matthew F Grady,David Howell","doi":"10.1016/j.jshs.2025.101058","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101058","url":null,"abstract":"BACKGROUNDEarly identification of concussion-related vision disorders (CRVDs) may improve outcomes by enabling earlier management, referral, and treatment. Objective eye tracking may provide additional data to support the diagnose of CRVDs. The purpose of this study was to determine the utility of objective infrared eye tracking in identifying CRVDs among adolescents experiencing persisting post-concussive symptoms (PPCS) more than 28 days after injury.METHODSThis was a prospective study of adolescents with PPCS evaluated with visio-vestibular examination (VVE), comprehensive vision examination, and an eye tracking device.RESULTSOf the 108 adolescents enrolled, 67 (62%) were diagnosed with a CRVD by comprehensive vision examination. On VVE, the near point of convergence break (5.5 ± 3.2 cm (mean ± SD) vs. 3.9 ± 1.7 cm, p < 0.001) and recovery (8.1 ± 3.3 cm vs. 6.8 ± 2.3 cm, p = 0.02) distinguished between those with and without CRVD. Concussion symptom provocation on VVE with horizontal saccades (35 (52%) vs. 12 (29%), p = 0.02) and horizontal vestibulo-ocular reflex testing (37 (55%) vs. 14 (34%), p = 0.03), and sway on tandem gait under the forward eyes closed condition (25 (37%) vs. 6 (15%), p = 0.01) also identified those with CRVD. From the eye tracking device, the BOX score (8.1 ± 5.8 vs. 5.2 ± 4.1, p = 0.007) and a metric of the left eye tracking along the bottom of the visual target (0.094 ± 0.500 vs. -0.124 ± 0.410, p = 0.02) identified those with CRVD, with a multivariable receiver operating characteristic curve analysis, including the BOX score, achieving an area under the receiver operating characteristic curve of 0.7637.CONCLUSIONCRVDs are common in those with PPCS, with impact on recovery after concussion. Novel eye-tracking metrics can serve as an aid in the identification of those with CRVDs who would benefit from referral for comprehensive diagnosis and treatment.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"59 1","pages":"101058"},"PeriodicalIF":11.7,"publicationDate":"2025-05-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144136837","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hiago L R Souza, Géssyca T Oliveira, Anderson Meireles, Marcelo P Dos Santos, João G Vieira, Rhai A Arriel, Stephen D Patterson, Moacir Marocolo
{"title":"Response to the comment on \"Does ischemic preconditioning enhance sports performance more than placebo or no intervention? A systematic review with meta-analysis\".","authors":"Hiago L R Souza, Géssyca T Oliveira, Anderson Meireles, Marcelo P Dos Santos, João G Vieira, Rhai A Arriel, Stephen D Patterson, Moacir Marocolo","doi":"10.1016/j.jshs.2025.101057","DOIUrl":"10.1016/j.jshs.2025.101057","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101057"},"PeriodicalIF":9.7,"publicationDate":"2025-05-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12276439/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144103081","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Daniel K Y Zheng,Jae Q J Liu,Jeremy R Chang,Jeffrey C Y Ng,Zhixing Zhou,Jinlong Wu,Chelsia K C Cheung,Frank F Huang,Sabina M Pinto,Dino Samartzis,Manuela L Ferreira,Kanchana Ekanayake,Stephen Lord,Xueqiang Wang,Arnold Y L Wong
{"title":"Erratum to \"are changes in pain intensity related to changes in balance control in individuals with chronic non-specific low back pain? A systematic review and meta-analysis\" version of record: 23 January 2025.","authors":"Daniel K Y Zheng,Jae Q J Liu,Jeremy R Chang,Jeffrey C Y Ng,Zhixing Zhou,Jinlong Wu,Chelsia K C Cheung,Frank F Huang,Sabina M Pinto,Dino Samartzis,Manuela L Ferreira,Kanchana Ekanayake,Stephen Lord,Xueqiang Wang,Arnold Y L Wong","doi":"10.1016/j.jshs.2025.101053","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101053","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"32 1","pages":"101053"},"PeriodicalIF":11.7,"publicationDate":"2025-05-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144087483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}