Journal of Sport and Health Science最新文献

{"title":"Quo vadis advanced footwear technology research?","authors":"Steffen Willwacher, Yannick Denis, Patrick Mai, Carlo von Diecken, Luca Braun","doi":"10.1016/j.jshs.2025.101071","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101071","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"656 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The lasting impacts of relative energy deficiency in sport imposed on pregnancy health outcomes: A survey-based investigation","authors":"Paris AT. Jones, Emma Brockwell, Sinéad Dufour, Amal Hassan, Brittany A. Matenchuk, Margie H. Davenport","doi":"10.1016/j.jshs.2025.101072","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101072","url":null,"abstract":"Relative energy deficiency in sport (REDs) results from exposure to problematic low energy availability. It is a serious condition affecting the health and athletic performance of up to 80% of elite female athletes. REDs is established to have negative short-term effects on reproductive function, but the long-term impact of this condition is unknown. Therefore, we examined the impact of secondary amenorrhea with or without a concurrent diagnosis of REDs on perinatal health outcomes.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"18 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144515504","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hamstring muscle architecture and microstructure changes following Nordic hamstring exercise training and detraining.","authors":"Anoosha Pai S, Max H Andrews, Reed D Gurchiek, Patricio A Pincheira, Marco Barbieri, Tyler Friedrich, Feliks Kogan, Garry E Gold, Valentina Mazzoli, Glen A Lichtwark, Scott L Delp, Akshay S Chaudhari","doi":"10.1016/j.jshs.2025.101070","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101070","url":null,"abstract":"<p><p>Background While Nordic hamstring exercise (NHE) training has been shown to reduce hamstring strains, the muscle-specific adaptations to NHE across the 4 hamstrings remain unclear. This study investigates architectural and microstructural adaptations of the biceps femoris short head (BFsh), biceps femoris long head (BFlh), semitendinosus (ST), and semimembranosus (SM) in response to an NHE intervention. Methods Eleven subjects completed 9 weeks of supervised NHE training followed by 3 weeks of detraining. Magnetic resonance imaging was performed at pre-training, post-training, and detraining to assess architectural (volume, fiber tract length, and fiber tract angle) and microstructural (axial (AD), mean (MD), radial (RD) diffusivities, and fractional anisotropy (FA)) parameters of the 4 hamstrings. Results NHE training induced significant but non-uniform hamstring muscle hypertrophy (BFsh: 22%, BFlh: 9%, ST: 26%, SM: 6%) and fiber tract length increase (BFsh: 11%, BFlh: 7%, ST: 18%, SM: 10%). AD (5%), MD (4%), and RD (5%) showed significant increases, but fiber tract angle and FA remained unchanged. After detraining, only ST showed a significant reduction (8%) in volume, which remained higher than the pre-training value. While fiber tract lengths returned to baseline, AD, MD, and RD remained higher than pre-training levels for all hamstrings. Conclusion The 9-week NHE training substantially increased hamstring muscle volume with greater hypertrophy in ST and BFsh. Hypertrophy was accompanied by increases in fiber tract lengths and cross-sections (increased RD). After 3 weeks of detraining, fiber tract length gains across all hamstrings declined, emphasizing the importance of sustained training to maintain all the protective adaptations.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101070"},"PeriodicalIF":9.7,"publicationDate":"2025-06-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144512602","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The effects of running shoe longitudinal bending stiffness and midsole energy return on oxygen consumption and ankle mechanics and energetics: A systematic review and meta-analysis","authors":"Cameron H.N. Stephen, Luke A. Kelly, Robert W. Schuster, Laura E. Diamond","doi":"10.1016/j.jshs.2025.101069","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101069","url":null,"abstract":"We aimed to investigate the effects of running shoe longitudinal bending stiffness (LBS) and midsole energy return on running economy and ankle mechanics and energetics.","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"36 1","pages":""},"PeriodicalIF":11.7,"publicationDate":"2025-06-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144341048","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise and cancer outcomes: What do we know and where next?","authors":"Lee W Jones","doi":"10.1016/j.jshs.2025.101068","DOIUrl":"https://doi.org/10.1016/j.jshs.2025.101068","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"51 1","pages":"101068"},"PeriodicalIF":11.7,"publicationDate":"2025-06-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144335275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise as a cancer treatment: New evidence from preclinical and early phase clinical studies.","authors":"Kerry S Courneya","doi":"10.1016/j.jshs.2025.101066","DOIUrl":"10.1016/j.jshs.2025.101066","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101066"},"PeriodicalIF":9.7,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Metabolome trajectories in male and female athletes.","authors":"Harald Schoeny, Bruno Stelzer, Theresa Hofbauer, Florian Reisenbauer, Yasin El Abiead, Jürgen Scharhag, Gunda Koellensperger","doi":"10.1016/j.jshs.2025.101065","DOIUrl":"10.1016/j.jshs.2025.101065","url":null,"abstract":"<p><strong>Background: </strong>Integrating metabolomics in sports science provides valuable insights into the biochemistry of bodies during physical activity. However, due to their invasiveness, traditional blood sampling methods present challenges in sports settings. The study investigated sex-specific metabolic responses, addressing a significant gap in exercise research, where female participation remains underrepresented.</p><p><strong>Methods: </strong>To address this, we explored volumetrically accurate microsampling as a dried blood spot (DBS) technique for assessing metabolomic changes in response to acute exercise in more than 130 participants. This study employed a targeted quantitative approach using isotopically labeled internal standards to measure over 100 metabolites with DBS, providing accurate and traceable results. An accuracy assessment using standard reference material and stability testing over 90 days further evaluated the suitability of DBS for sports metabolomics.</p><p><strong>Results: </strong>Our findings confirm that DBS offers a valid approach to capture metabolic changes during exercise, with 11 compounds within the confidence interval of the reference material and 59 compounds overlapping with database values. A wide panel of metabolites showed significant changes in differences of absolute concentrations upon bout exercise, with succinate and xanthine being the most significant compounds. Metabolites from the underexplored class of pyrimidines also showed significant changes.</p><p><strong>Conclusion: </strong>While metabolic regulations upon exercise are similar in both sexes, differences in the correlation with fitness-related metadata, such as peak volitional oxygen consumption and performance, indicate a higher complexity in women and a limitation of previous knowledge to men only. The quantification approach together with the simplicity of the sampling paves the way to expand this type of research toward other fields of personalized medical services.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101065"},"PeriodicalIF":9.7,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295171","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Practical recommendations on stretching exercise: A Delphi consensus statement of international research experts.","authors":"Konstantin Warneke, Ewan Thomas, Anthony J Blazevich, José Afonso, David G Behm, Paulo H Marchetti, Gabriel S Trajano, Masatoshi Nakamura, Francisco Ayala, Stefano Longo, Nicolas Babault, Sandro R Freitas, Pablo B Costa, Andreas Konrad, Antoine Nordez, Arnold Nelson, Astrid Zech, Anthony D Kay, Olyvia Donti, Jan Wilke","doi":"10.1016/j.jshs.2025.101067","DOIUrl":"10.1016/j.jshs.2025.101067","url":null,"abstract":"<p><strong>Background: </strong>Stretching has wide appeal, but there seems to exist some mismatch between its purported applications and what the evidence shows. There is compelling evidence for some stretching applications, but for others, the evidence seems heterogeneous or unsupportive. The discrepancies even affect some systematic reviews, possibly due to heterogeneous eligibility criteria and search strategies. This consensus paper seeks to unify the divergent findings on stretching and its implications for both athletic performance and clinical practices by delivering evidence-based recommendations.</p><p><strong>Methods: </strong>A panel of 20 experts with a blend of practical experience and scholarly knowledge was assembled. The panel meticulously reviewed existing systematic reviews, defined key terminologies (e.g., consensus definitions for different stretching modes), and crafted guidelines using a Delphi consensus approach (minimum required agreement: 80%). The analysis focused on 8 topics, including stretching's acute and chronic (long-term) effects on range of motion, strength performance, muscle hypertrophy, stiffness, injury prevention, muscle recovery, posture correction, and cardiovascular health.</p><p><strong>Results: </strong>There was consensus that chronic and acute stretching (a) improves range of motion (although alternatives exist) and (b) reduces muscle stiffness (which may not always be desirable); the panel also agreed that chronic stretching (c) may promote vascular health, but more research is warranted. In contrast, consensus was found that stretch training does not (a) contribute substantively to muscle growth, (b) serve as an all-encompassing injury prevention strategy, (c) improve posture, or (d) acutely enhance post-exercise recovery.</p><p><strong>Conclusion: </strong>These recommendations provide guidance for athletes and practitioners, highlighting research gaps that should be addressed to more comprehensively understand the full scope of stretching effects.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101067"},"PeriodicalIF":9.7,"publicationDate":"2025-06-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prehabilitation during neoadjuvant chemotherapy results in an enhanced immune response in esophageal adenocarcinoma tumors: A randomized controlled trial.","authors":"Charles J Rayner, David B Bartlett, Sophie K Allen, Tyler Wooldridge, Tadd Seymour, Sunny Sunshine, Julie Hunt, David King, Izhar Bagwan, Javed Sultan, Shaun R Preston, Adam E Frampton, Nicola E Annels, Nima Abbassi-Ghadi","doi":"10.1016/j.jshs.2025.101063","DOIUrl":"10.1016/j.jshs.2025.101063","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;For patients with locally advanced esophagogastric cancer, the standard of care in the UK is neoadjuvant chemotherapy (NAC) followed by surgery. Prehabilitation exercise training can improve physiological function and fitness. If such improvements translate to increased immune infiltration of tumors, exercise could be prescribed as an immune adjuvant during NAC and potentially improve clinical outcomes. As such, we aimed to determine whether prehabilitation increased tumor infiltrating lymphocytes (TILs).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;We assessed 22 patients with locally advanced esophageal cancer on a randomized control trial comparing 16 weeks of low-to-moderate intensity twice weekly supervised and thrice weekly home-based exercise (Prehab: n = 11) to no prehabilitation (Control: n = 11). Our primary outcome was to compare tumor-immune responses between Controls and Prehab. We compared formalin-fixed paraffin-embedded tumors by high-resolution multispectral immunohistochemistry (mIHC) and NanoString spatial transcriptomics. Secondarily, we determined relationships between changes in fitness to the exercise training and tumor-immune measures. Specifically, we assessed percentage changes in peak cardiorespiratory fitness as assessed by peak oxygen uptake (V̇O&lt;sub&gt;2peak&lt;/sub&gt;) before NAC (Baseline) and after 8 weeks of NAC (Post-NAC), and changes between Baseline and following 8 weeks of NAC recovery before surgery (Pre-surgery) and correlated changes in fitness with tumor-immune responses. Finally, as an exploratory aim, we assessed clinical outcomes between groups, including survival, therapy tolerance, and tumor regrading.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;We observed that Prehab had significantly more CD8+ lymphocytes in their tumors (mean difference (diff.) = 1.79, 95% confidence interval (95% CI): 0.76‒2.82, p &lt; 0.001) and their stroma (mean diff. = 1.59, 95% CI: 0.66‒2.52, p &lt; 0.001) than the Controls. When normalized to total numbers of TILs, Prehab had higher levels of CD56+ NK cells (median diff. = 0.87, 95% CI: 0.25‒2.18), p = 0.0274), consisting primarily of CD56&lt;sup&gt;dim&lt;/sup&gt; NK cells (median diff. = 0.48, 95% CI: 0.03‒2.53), p = 0.0464). Evaluation of the presence and localization of tumor-associated tertiary lymphoid structures (TLS) in the esophageal tumors revealed that most TLS were in the peritumoral regions. Prehab had a higher TLS cell density (cells/mm&lt;sup&gt;2&lt;/sup&gt;; median diff. = 18,959, 95% CI: 13,518‒22,635), p &lt; 0.001) and more clearly defined germinal centers indicative of mature TLS visually. We observed that Prehab maintained their V̇O&lt;sub&gt;2peak&lt;/sub&gt; during NAC while the Controls' V̇O&lt;sub&gt;2peak&lt;/sub&gt; reduced by 9.0% ± 10.2% (mean ± SD) (Post-NAC: p = 0.018). Pre-surgery, Prehab V̇O&lt;sub&gt;2peak&lt;/sub&gt; was a clinically meaningful 3.27 ± 1.31 mL/kg/min higher than Controls (p = 0.022). Between Baseline and Post-NAC, where the Prehab maintained V̇O&lt;sub&gt;2peak&lt;/sub&gt; better than Controls, there w","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101063"},"PeriodicalIF":9.7,"publicationDate":"2025-06-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144276395","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of aerobic or resistance exercise during neoadjuvant chemotherapy on tumor response and therapy completion in women with breast cancer: The randomized controlled BENEFIT trial.","authors":"Martina E Schmidt, Siri Goldschmidt, Charlotte Kreutz, Jana Müller, Andreas Schneeweiss, Anne M May, Friederike Rosenberger, Joachim Wiskemann, Karen Steindorf","doi":"10.1016/j.jshs.2025.101064","DOIUrl":"10.1016/j.jshs.2025.101064","url":null,"abstract":"<p><strong>Background: </strong>The potential of exercise as a concurrent therapy for actively treated primary tumors has been suggested by emerging preclinical and observational studies. However, clinical trials regarding this question are scarce. Therefore, we conducted a randomized controlled trial investigating the effects of aerobic or resistance exercise concomitant to neoadjuvant chemotherapy (NACT) on tumor size.</p><p><strong>Methods: </strong>In the BENEFIT study (German title: Bewegung bei neoadjuvanter chemotherapie zur verbesserung der fitness), patients with breast cancer scheduled for NACT were randomly assigned to supervised resistance training (RT, n = 60) or aerobic training (AT, n = 60) twice weekly during NACT or to a waitlist control group (WCG, n = 60). The primary outcome, \"change in tumor size,\" as well as the secondary clinical outcomes pathologic complete response (pCR), type of surgery (breast conserving/mastectomy), axillary lymph node dissection (ALND, yes/no), premature discontinuation of chemotherapy (yes/no), and relative dose intensity (RDI) were derived from clinical records. Due to the highly skewed distribution, the primary outcome was categorized. Multiple (ordinal) logistic regression analyses were performed.</p><p><strong>Results: </strong>Overall, there was no significant difference in post-intervention tumor size between RT or AT and WCG. However, there was a significant effect modification by hormone receptor (HR) status (p_interaction = 0.030). Among patients with HR+ tumors, results suggest a beneficial effect of AT on tumor shrinkage (odds ratio (OR) = 2.37, 95% CI: 0.97‒5.78), on pCR (OR = 3.21, 95% CI: 0.97‒10.61); and on ALND (OR = 3.76, 95% CI: 0.78‒18.06) compared to WCG. The effects of RT were slightly less pronounced. For HR- subtypes, beneficial effects on RDI were found for AT (OR = 3.71, 95% CI: 1.20‒11.50) and similarly for RT (OR = 2.58, 95% CI: 0.88‒7.59). Both AT and RT had favorable effects on premature discontinuation of chemotherapy (OR (no vs. yes) = 2.34, 95% CI: 1.10‒5.06), irrespective of tumor receptor status.</p><p><strong>Conclusion: </strong>While there was no significant effect on the primary outcome in the overall group, aerobic and resistance exercise concomitant to NACT seem to beneficially affect tumor shrinkage and pCR, reduce the need for ALND among patients with HR+ breast cancers, and prevent low RDI among patients with HR- breast cancers. These results warrant confirmation in further trials.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101064"},"PeriodicalIF":9.7,"publicationDate":"2025-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144188323","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}