Journal of Sport and Health Science最新文献

{"title":"School uniforms and physical activity inequalities: Interpreting global evidence in context.","authors":"Carina Joane V Barroso, Beulah Joy K Damasco, Mariz Rochelle C Sedon, Hazel Ann O Olvida","doi":"10.1016/j.jshs.2026.101183","DOIUrl":"https://doi.org/10.1016/j.jshs.2026.101183","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101183"},"PeriodicalIF":13.1,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196913","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise oncology and tumor sterol metabolism: An emerging mechanistic frontier","authors":"Marc Poirot,Philippe de Médina,Sandrine Silvente-Poirot","doi":"10.1016/j.jshs.2026.101181","DOIUrl":"https://doi.org/10.1016/j.jshs.2026.101181","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"86 1","pages":"101181"},"PeriodicalIF":11.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149150027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Association of ophthalmic disease and physical activity in All of Us Research Program","authors":"Nikhil Chatra,Amin Nabavi,Swarup S. Swaminathan,Felipe A. Medeiros,Siamak Yousefi","doi":"10.1016/j.jshs.2026.101182","DOIUrl":"https://doi.org/10.1016/j.jshs.2026.101182","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":"10 1","pages":"101182"},"PeriodicalIF":11.7,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149150026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neural and computational mechanisms of embodied learning: From brain-body interaction to translational applications.","authors":"Qian Yu, Zhihao Zhang, Peng Wang, Markus Raab, Fabian Herold, Matthew Heath, Myrto Mavilidi, Fred Paas, Liye Zou","doi":"10.1016/j.jshs.2026.101177","DOIUrl":"10.1016/j.jshs.2026.101177","url":null,"abstract":"<p><strong>Background: </strong>Embodied learning views cognition as emerging from dynamic body-environment interactions, but evidence remains fragmented across neural, computational, developmental, and applied domains. This review aims to clarify how sensorimotor and interoceptive processes shape learning and to develop an integrative mechanistic framework.</p><p><strong>Methods: </strong>We performed a narrative, interdisciplinary synthesis of theoretical and empirical evidence spanning systems and developmental neuroscience, computational modeling, neurorehabilitation, neurotechnology, and embodied artificial intelligence. Evidence was organized across neural substrates, learning algorithms, behavioral functions, developmental and evolutionary perspectives, and translational applications.</p><p><strong>Results: </strong>Sensorimotor cortices and parietal-premotor networks integrate perception and action; the cerebellum implements error-driven forward models; basal ganglia and dopaminergic systems support reward-based action updating; and hippocampal and interoceptive-affective networks embed bodily experience in contextual memory and physiological regulation. Predictive coding and active inference, reinforcement learning, and Hebbian plasticity provide complementary computational accounts whose contributions vary with uncertainty, reward, and learning stage. Based on this synthesis, we propose the Integrative Embodied Learning Framework (IELF), a three-layer model linking computational mechanisms with overlapping neural systems and behavioral outcomes. IELF generates testable predictions and extends embodied learning to developmental and evolutionary trajectories, neurological rehabilitation, and biologically inspired artificial intelligence.</p><p><strong>Conclusion: </strong>Learning emerges through recurrent brain-body-environment loops rather than isolated brain processes. IELF provides a unified mechanistic scaffold for testing embodied learning and developing personalized, closed-loop rehabilitation and adaptive artificial agents.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101177"},"PeriodicalIF":13.1,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991907","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methylome-transcriptome integration reveals molecular signatures of intrinsic aerobic capacity in aged skeletal muscle.","authors":"Lei Zhou, Soroosh Mozaffaritabar, Ferenc Torma, Erika Koltai, Takuji Kawamura, Mitsuru Higuchi, Zhentao Zhong, Lauren Gerard Koch, Steven Loyal Britton, Zsolt Radák","doi":"10.1016/j.jshs.2026.101178","DOIUrl":"10.1016/j.jshs.2026.101178","url":null,"abstract":"<p><strong>Background: </strong>Intrinsic aerobic capacity is a critical determinant of metabolic health and healthy aging, yet its epigenomic and transcriptomic features in aged skeletal muscle, and whether these intrinsic differences are accompanied by distinct exercise-related molecular responses, remain unclear.</p><p><strong>Methods: </strong>Soleus muscle from aged selectively bred high- and low-running capacity rats (HCR and LCR; 23-24 months) was profiled by reduced representation bisulfite sequencing (RRBS) and RNA sequencing (RNA-seq). Differentially methylated regions (DMRs) were annotated, functionally enriched, integrated with differentially expressed genes (DEGs), and correlated with maximal oxygen uptake (VO₂_max). An age-comparable voluntary-running cohort was further analyzed by RNA-seq and selected protein profiling to assess exercise adaptation.</p><p><strong>Results: </strong>RRBS identified broad baseline methylome remodeling, including 7196 significant DMRs, with a higher proportion of hypermethylated regions in HCR muscle. These DMRs were mainly localized to open-sea CpGs, while gene-associated DMRs were predominantly intronic and exonic, and showed context-dependent functional enrichment. Baseline RNA-seq identified 322 DEGs between HCR and LCR muscle. Methylome-transcriptome integration revealed 72 DMR-DEG pairs representing 53 unique genes, mostly located in open-sea, intronic, and exonic regions. Exploratory VO_2max analysis identified 63 DMRs associated with aerobic capacity. Chronic voluntary running induced more DEGs in HCR than in LCR muscle, while pathway-level responses in both lines converged on mitochondrial and oxidative metabolism. Selected protein profiling further revealed mainly baseline LCR-HCR differences, with limited additional exercise-associated changes.</p><p><strong>Conclusion: </strong>Intrinsic high aerobic capacity in aged skeletal muscle is associated with hypermethylation-enriched methylome remodeling, feature-dependent functional enrichment, distinct transcriptional signatures, and oxidative-metabolic protein differences. These findings provide a multi-layer molecular framework for understanding intrinsic aerobic-capacity divergence in aged skeletal muscle and highlight candidate regulatory regions for future functional validation.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101178"},"PeriodicalIF":13.1,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991889","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Participation in an exercise program after primary glioblastoma diagnosis is associated with attenuated tumor volume, performance status decline, and development of sarcopenic adiposity at recurrence.","authors":"Fabian M Troschel, Johanna Engl, Benjamin O Troschel, Romy Potthoff, Niklas Benedikt Pepper, Ralf Brandt, Maren Kloss, Rainer Wiewrodt, Walter Stummer, Dorothee Wiewrodt, Hans Theodor Eich","doi":"10.1016/j.jshs.2026.101176","DOIUrl":"10.1016/j.jshs.2026.101176","url":null,"abstract":"<p><strong>Objective: </strong>Here, we investigate whether participation in a structured exercise program after initial diagnosis is linked to modified muscle and fat measurements, performance status, tumor characteristics, and, ultimately, overall survival (OS) in recurrent glioblastoma patients.</p><p><strong>Methods: </strong>Included in this study were 201 consecutive glioblastoma patients (isocitrate dehydrogenase 1 (IDH1) wildtype) diagnosed between 2010 and 2023 with available primary and recurrence imaging. Of these, 25 (12.4%) participated in a structured exercise program after diagnosis. Patient characteristics at primary diagnosis and at recurrence were collected and muscle, inter-/intramuscular adipose tissue (IMAT), and subcutaneous adipose tissue (SAT) compartments of the neck were quantified on initial and recurrence radiation simulation CT scans. Time-to-event analyses were then run for OS from recurrence.</p><p><strong>Results: </strong>Participants in the exercise program had lower tumor volumes (p = 0.025) and better Eastern Cooperative Oncology Group (ECOG) scores (p = 0.016) at recurrence than non-participants despite no differences at initial diagnosis (p > 0.8 for both). Exercise program participants also demonstrated reduced development of sarcopenic adiposity (i.e., a decline in muscle and an increase in IMAT and SAT measurements) in univariable and multivariable analyses. Exercise program participation, tumor volume, ECOG score, and sarcopenic adiposity measures showed univariable associations with post-recurrence OS (p < 0.05). Tumor volume at recurrence and increase in sarcopenic adiposity during treatment retained significance in multivariable models (p < 0.01) while exercise program participation itself did not (p = 0.11).</p><p><strong>Conclusion: </strong>This exploratory retrospective observational cohort study comparing prospectively enrolled exercise program participants with non-participants finds a close interplay between exercise program participation, muscle and fat dynamics, performance status, and tumor volume, linking structured exercise to prognostically favorable changes in patient and tumor characteristics. While results encourage exercise in glioblastoma, prospective randomized trials are needed to substantiate findings.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101176"},"PeriodicalIF":13.1,"publicationDate":"2026-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148991877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reframing exercise training \"non-response\" as dose vulnerability in AI-guided cardiac rehabilitation.","authors":"Zhang Liu, Weiqin Huang","doi":"10.1016/j.jshs.2026.101173","DOIUrl":"10.1016/j.jshs.2026.101173","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101173"},"PeriodicalIF":13.1,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907705","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lifelong strength training in knee osteoarthritis: Functional reserve rather than disease modification.","authors":"Xiaoye Tang, Jialu Zhang, Baoqing Yu","doi":"10.1016/j.jshs.2026.101174","DOIUrl":"10.1016/j.jshs.2026.101174","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101174"},"PeriodicalIF":13.1,"publicationDate":"2026-09-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148907575","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The \"neuromuscular primer\" in osteogenic exercise.","authors":"Yan Liang, Bing Hou, Haiying Liu","doi":"10.1016/j.jshs.2026.101172","DOIUrl":"10.1016/j.jshs.2026.101172","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101172"},"PeriodicalIF":13.1,"publicationDate":"2026-09-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148892691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Differential neurological adaptations during rehabilitation and at the time of return to sports in individuals with anterior cruciate ligament reconstruction: A systematic review and meta-analysis.","authors":"Yifan Wu, Shiyi Yao, Tingjun Ye, Yiyan Liu, Lin Wang, Michael Tim-Yun Ong, Lei Wang, Patrick Shu-Hang Yung, Jihong Qiu","doi":"10.1016/j.jshs.2026.101171","DOIUrl":"10.1016/j.jshs.2026.101171","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Individuals with anterior cruciate ligament reconstruction (ACLR) demonstrated neurological adaptations, but it remains unclear how these changes evolve from rehabilitation to return to sport (RTS) and how they affect quadriceps neuromuscular weakness. Therefore, this review aims to: (a) compare the activation in the cerebral cortex as well as the corticospinal and spinal tract of quadriceps between individuals with ACLR and healthy controls; (b) determine the effects of the neurological alterations on quadriceps neuromuscular function during rehabilitation and RTS.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Methods: &lt;/strong&gt;A systematic search was conducted across PubMed, Web of Science, Medline, and SPORTDiscus. Risk of bias was assessed by the Methodological Index for Non-randomized Studies checklist and Egger's test. The evidence certainty was evaluated by the Grading of Recommendations Assessment, Development, and Evaluation guidelines. Participant characteristics, time of data collection, the stage of rehabilitation (&lt;12 months post-ACLR) or RTS (≥12 months post-ACLR), data on neurological measures (cortical activation, corticospinal and spinal excitability), data on quadriceps neuromuscular function (strength, rate of torque development (RTD), central activation ratio (CAR)), and relevant results in individual studies were extracted and synthesized in a narrative or quantitative format.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Twenty studies involving 504 individuals with ACLR and 362 healthy controls were included, with certainty levels rated low to very low. Compared to healthy controls, individuals with ACLR exhibited increased active/resting motor threshold (AMT/RMT) in the nonsurgical limb only (standardized mean difference (SMD) = 0.64, p = 0.009), comparable interval intracortical facilitation and short interval intracortical inhibition, bilateral increased motor evoked potential (MEP) amplitudes (surgical: SMD = 0.71, p = 0.02; nonsurgical: SMD = 0.32, p = 0.03), and comparable H-reflex/M-wave ratio (H/M ratio), with the MEP amplitudes negatively associated with quadriceps strength during rehabilitation. At RTS, individuals with ACLR presented greater activation in frontal and parietal regions in the brain cortex contralateral to the surgical limb during knee flexion/extension movements, increased AMT/RMT (SMD = 0.73, p = 0.003) and H/M ratio (SMD = 0.33, p = 0.0009) in the surgical limb, with a negative association between AMT/RMT and quadriceps CAR.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion: &lt;/strong&gt;Individuals with ACLR demonstrate bilateral corticospinal maladaptations in the quadriceps during rehabilitation (&lt;12 months post-ACLR), and the alterations in the cortical, corticospinal, and spinal excitability in the surgical limb remain unresolved at the time of RTS (≥12 months post-ACLR). These neurological alterations are associated with quadriceps neuromuscular function, which underscores the importance of incorporating bilateral neurophysiological","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101171"},"PeriodicalIF":13.1,"publicationDate":"2026-09-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148882307","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}