Journal of Sport and Health Science最新文献

{"title":"Multiscale hamstring muscle adaptations following 9 weeks of eccentric training.","authors":"Max H Andrews, Anoosha Pai S, Reed D Gurchiek, Patricio A Pincheira, Akshay S Chaudhari, Paul W Hodges, Glen A Lichtwark, Scott L Delp","doi":"10.1016/j.jshs.2024.100996","DOIUrl":"10.1016/j.jshs.2024.100996","url":null,"abstract":"<p><strong>Background: </strong>Eccentric training, such as Nordic hamstring exercise (NHE) training, is commonly used as a preventive measure for hamstring strains. Eccentric training is believed to induce lengthening of muscle fascicles and to be associated with the addition of sarcomeres in series within muscle fibers. However, the difficulty in measuring sarcomere adaptation in human muscles has severely limited information about the precise mechanisms of adaptation. This study addressed this limitation by measuring the multiscale hamstring muscle adaptations in response to 9 weeks of NHE training and 3 weeks of detraining.</p><p><strong>Methods: </strong>Twelve participants completed 9 weeks of supervised NHE training, followed by a 3-week detraining period. We assessed biceps femoris long-head (BFlh) muscle fascicle length, sarcomere length, and serial sarcomere number in the central and distal regions of the muscle. Additionally, we measured muscle volume and eccentric strength at baseline, post-training, and post-detraining.</p><p><strong>Results: </strong>NHE training over 9 weeks induced significant architectural and strength adaptations in the BFlh muscle. Fascicle length increased by 19% in the central muscle region and 33% in the distal muscle region. NHE also induced increases in serial sarcomere number (25% in the central region and 49% in the distal region). BFlh muscle volume increased by 8%, and knee flexion strength increased by 40% with training. Following 3 weeks of detraining, fascicle length decreased by 12% in the central region and 16% in the distal region along with reductions in serial sarcomere number.</p><p><strong>Conclusion: </strong>Nine weeks of NHE training produced substantial, region-specific increases in BFlh muscle fascicle length, muscle volume, and force generation. The direct measurement of sarcomere lengths revealed that the increased fascicle length was accompanied by the addition of sarcomeres in series within the muscle fascicles.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"100996"},"PeriodicalIF":10.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863337/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exercise as a cancer treatment: New evidence from preclinical and early phase clinical studies.","authors":"Kerry S Courneya","doi":"10.1016/j.jshs.2025.101066","DOIUrl":"10.1016/j.jshs.2025.101066","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101066"},"PeriodicalIF":10.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12270073/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effort minimization: A permanent, dynamic, and surmountable influence on physical activity.","authors":"Silvio Maltagliati, Layan Fessler, Qian Yu, Zhihao Zhang, Yanxia Chen, Olivier Dupuy, Ryan S Falck, Neville Owen, Liye Zou, Boris Cheval","doi":"10.1016/j.jshs.2024.100971","DOIUrl":"10.1016/j.jshs.2024.100971","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"100971"},"PeriodicalIF":13.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11809139/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142134270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Toe-out landing reduces anterior talofibular ligament strain while maintains calcaneofibular ligament strain in people with chronic ankle instability.","authors":"Xiaoxue Zhu, Feng Wei, Simin Li, Teng Zhang, Peixin Shen, Daniel Tp Fong, Qipeng Song","doi":"10.1016/j.jshs.2025.101035","DOIUrl":"10.1016/j.jshs.2025.101035","url":null,"abstract":"<p><strong>Background: </strong>The anterior talofibular ligament (ATFL) and the calcaneofibular ligament (CFL) are vulnerable to be torn or ruptured during lateral ankle sprain (LAS), especially in people with chronic ankle instability (CAI). This study aims to determine whether landing with a larger toe-out angle would influence ATFL and CFL strains in people with CAI, aiming to contribute to the development of effective landing strategies to reduce LAS risk.</p><p><strong>Methods: </strong>Thirty participants with CAI (22 males and 8 females, age: 21.2 ± 1.2 years, height: 176.9 ± 9.0 cm, body mass: 70.6 ± 12.1 kg, mean ± SD) were recruited. Each participant landed on a specialized trap-door device with their unaffected limbs on a support platform and their affected limbs on a movable platform, which could be flipped 24° inward and 15° forward to mimic LAS conditions. Two landing conditions were tested-i.e., natural landing (NL, with natural toe-out angle at landing) and toe-out landing (TL, with toe-out angle increased to over 150% of that under the NL conditions). Kinematic data were captured using a 12-camera motion analysis system, and ATFL and CFL strains were calculated using a 3D rigid-body foot model. Paired sample t tests and Pearson's correlations were used to analyze data.</p><p><strong>Results: </strong>Compared to NL conditions, ATFL strain decreased (p < 0.001, d = 2.42) while CFL strain remained unchanged (p = 0.229, d = 0.09) under TL conditions. The toe-out angle was negatively and strongly correlated with ATFL strain (r = -0.743, p < 0.001) but not with CFL strain (r = 0.153, p = 0.251). Compared to NL conditions, participants exhibit a lower ankle inversion angle (p < 0.001, d = 0.494), a higher plantarflexion angle (p < 0.001, d = 1.101), and no significant difference in external rotation angle (p = 0.571, d = 0.133) under TL conditions.</p><p><strong>Conclusion: </strong>Toe-out landing may reduce ATFL strain while maintaining CFL strain in people with CAI, thereby reducing the risk of LAS.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101035"},"PeriodicalIF":13.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12478106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143532072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exerkines: Potential regulators of ferroptosis.","authors":"Min Jia, Fengxing Li, Tong Wu, Ning Chen","doi":"10.1016/j.jshs.2025.101032","DOIUrl":"10.1016/j.jshs.2025.101032","url":null,"abstract":"<p><p>Ferroptosis is a programmed cell death, and its mechanism involves multiple metabolic pathways, such as iron and lipid metabolism, and redox homeostasis. Exerkines are important mediators that optimize cellular homeostasis and maintain physiological health during exercise stimulation. This article comprehensively examines the mechanisms and regulatory networks for governing ferroptosis and summarizes the impact of exercise and exerkines on ferroptosis under varying load intensities and disease contexts. Notably, despite its significant efficacy and minimal side effects, the therapeutic and prognostic potential of exercise in ferroptosis-related diseases remains largely unexplored. This article, by summarizing recent progresses in the regulation of exerkines-mediated ferroptosis, could further uncover the preventive or alleviative mechanisms of some diseases upon exercise interventions, which will be beneficial to design exercise interventional strategies for alleviating disease progression through the regulation of ferroptosis.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101032"},"PeriodicalIF":13.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12002844/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484232","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Benefits and harms of exercise therapy and physical activity for low back pain: An umbrella review.","authors":"Josielli Comachio, Paula R Beckenkamp, Emma Kwan-Yee Ho, Christina Abdel Shaheed, Emmanuel Stamatakis, Manuela Loureiro Ferreira, Qianwen Lan, Paul Jarle Mork, Andreas Holtermann, Daniel Xin Mo Wang, Paulo H Ferreira","doi":"10.1016/j.jshs.2025.101038","DOIUrl":"10.1016/j.jshs.2025.101038","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this umbrella review was to synthesize the evidence from systematic reviews on the benefits and harms of exercise therapy and physical activity (PA) for the secondary prevention and management of low back pain (LBP).</p><p><strong>Methods: </strong>An umbrella review was conducted to evaluate the effectiveness of exercise therapy and PA in the management and secondary prevention of LBP. A systematic search was performed in MEDLINE, CINAHL, Scopus, Web of Science, Cochrane Database of Systematic Reviews, and Physiotherapy Evidence Database (PEDro), including reference lists of relevant reviews, covering studies published between January 1, 2010 and May 20, 2024. Eligible studies were systematic reviews of randomized controlled trials and observational studies, with or without meta-analyses. The primary outcome for secondary prevention was LBP recurrence, while for management, primary outcomes included pain intensity and disability, with adverse events as secondary outcomes. Data were extracted across immediate, short-term, intermediate, and long-term follow-up periods. The Grading of Recommendations Assessment, Development, and Evaluation (GRADE) framework was used to assess the certainty of evidence, and the Assessment of Multiple Systematic Reviews tool (AMSTAR) tool was applied by 2 independent reviewers (JC, QL, and/or DXMW) to evaluate the quality of the included reviews. The study was prospectively registered on the Open Science Framework (OSF).</p><p><strong>Results: </strong>A total of 70 systematic reviews were included, 43 with meta-analyses, 7 with network meta-analyses, and 20 without meta-analyses. Six (out of 10) reviews with meta-analyses for secondary prevention indicated a small benefit from general exercises and leisure-time PA (low-to-moderate certainty). For LBP management, 35 (out of 36) reviews reported that exercise therapies such as Pilates, motor control, mixed exercise, Tai Chi, water-based exercises, and yoga showed small beneficial effects on pain and disability compared to minimal intervention mainly in the short-term (low-to-moderate certainty). Seven network meta-analyses favored motor control and Pilates over other forms of exercise to reduce pain (low certainty). Adverse events were reported in less than 31% of the reviews, predominantly involving post-exercise soreness and temporary increases in pain, mainly in yoga-related studies. Adverse events were considered minor, and no serious adverse events were reported.</p><p><strong>Conclusion: </strong>There is low-to-moderate certainty that exercise therapy and leisure-time PA are beneficial for improving pain and preventing the recurrence of LBP. However, evidence on the potential harms of these interventions is limited, and adverse events related to exercise and PA remain under-investigated.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101038"},"PeriodicalIF":13.1,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12191304/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143781394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Promoting men's health through sports clubs: A systematic rapid realist review.","authors":"Anne Timm, Aurelie van Hoye, Paul Sharp, Tue Helms Andersen, Louise Hansen, Jane Nautrup Østergaard, Peter Krustrup, Kenneth Cortsen, Peter Bindslev Iversen, Morten Hulvej Rod, Charlotte Demant Klinker","doi":"10.1016/j.jshs.2024.100969","DOIUrl":"10.1016/j.jshs.2024.100969","url":null,"abstract":"<p><strong>Background: </strong>Health promotion (HP) interventions delivered through sports clubs have demonstrated promising outcomes among men, but less is known about which aspects of the interventions work, for whom, and under what circumstances. This rapid realist review aimed to understand the contexts, mechanisms, and outcomes of HP interventions for men delivered through sports clubs.</p><p><strong>Methods: </strong>A systematic literature search was conducted in February 2023 for studies published after 2013 in MEDLINE, Embase, and SPORTDiscus databases.</p><p><strong>Included studies: </strong>(a) were delivered by or in collaboration with sports clubs, (b) targeted men aged 18+ years, and (c) reported 1 or more HP outcomes. A grey literature search was also performed. Studies were included in a realist synthesis based on richness and rigor. Hereafter, context-mechanism-outcome (CMO) configurations were developed.</p><p><strong>Results: </strong>We identified and screened 3358 studies, finally including 59 studies describing 22 interventions. Most HP interventions were delivered in high income countries, included Caucasian men aged 35-65 years with overweight/obesity, and used professional sports clubs (mostly football) for recruitment and facilities. Quantitative HP outcomes were reported across 19 interventions. Of these 19 interventions, the majority reported on weight (n = 18), physical activity (n = 12), mental health (n = 10), and diet (n = 9). We identified 13 CMOs related to how HP interventions affected men's recruitment, engagement, and health behavior maintenance.</p><p><strong>Conclusion: </strong>Our findings show that using sports clubs for HP interventions is effective for engaging men. Recruitment was facilitated by leveraging sports clubs' identity, addressing masculinity-related barriers, improving accessibility, and building trust. Engagement was enhanced through shared identity experiences, safe spaces, inclusive competition, and self-efficacy. However, there's limited evidence on behavior maintenance post-intervention, though involving community stakeholders seemed vital. In general, considerations should be made to avoid perpetuating traditional masculine norms, which may exclude some men and reinforce unhealthy behaviors. These findings can guide intervention development, emphasizing the need to harness men's perspectives in the process.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"100969"},"PeriodicalIF":10.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863273/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142113803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Does ischemic preconditioning enhance sports performance more than placebo or no intervention? A systematic review with meta-analysis.","authors":"Hiago L R Souza, Géssyca T Oliveira, Anderson Meireles, Marcelo P Dos Santos, João G Vieira, Rhai A Arriel, Stephen D Patterson, Moacir Marocolo","doi":"10.1016/j.jshs.2024.101010","DOIUrl":"10.1016/j.jshs.2024.101010","url":null,"abstract":"<p><strong>Background: </strong>Ischemic preconditioning (IPC) is purported to have beneficial effects on athletic performance, although findings are inconsistent, with some studies reporting placebo effects. The majority of studies have investigated IPC alongside a placebo condition, but without a control condition that was devoid of experimental manipulation, thereby limiting accurate determination of the IPC effects. Therefore, the aims of this study were to assess the impact of the IPC intervention, compared to both placebo and no intervention, on exercise capacity and athletic performance.</p><p><strong>Methods: </strong>A systematic search of PubMed, Embase, SPORTDiscus, Cochrane Library, and Latin American and Caribbean Health Sciences Literature (LILACS) covering records from their inception until July 2023 was conducted. To qualify for inclusion, studies had to apply IPC as an acute intervention, comparing it with placebo and/or control conditions. Outcomes of interest were performance (force, number of repetitions, power, time to exhaustion, and time trial performance), physiological measurements (maximum oxygen consumption, and heart rate), or perceptual measurements (RPE). For each outcome measure, we conducted 3 independent meta-analyses (IPC vs. placebo, IPC vs. control, placebo vs. control) using an inverse-variance random-effects model. The between-treatment effects were quantified by the standardized mean difference (SMD), accompanied by their respective 95% confidence intervals. Additionally, we employed the Grading of Recommendations, Assessment, Development and Evaluation (GRADE) approach to assess the level of certainty in the evidence.</p><p><strong>Results: </strong>Seventy-nine studies were included in the quantitative analysis. Overall, IPC demonstrates a comparable effect to the placebo condition (using a low-pressure tourniquet), irrespective of the subjects' training level (all outcomes presenting p > 0.05), except for the outcome of time to exhaustion, which exhibits a small magnitude effect (SMD = 0.37; p = 0.002). Additionally, the placebo exhibited effects notably greater than the control condition (outcome: number of repetitions; SMD = 0.45; p = 0.03), suggesting a potential influence of participants' cognitive perception on the outcomes. However, the evidence is of moderate to low certainty, regardless of the comparison or outcome.</p><p><strong>Conclusion: </strong>IPC has significant effects compared to the control intervention, but it did not surpass the placebo condition. Its administration might be influenced by the cognitive perception of the receiving subject, and the efficacy of IPC as an ergogenic strategy for enhancing exercise capacity and athletic performance remains questionable.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101010"},"PeriodicalIF":10.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880722/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"GEPREP: A comprehensive data atlas of RNA-seq-based gene expression profiles of exercise responses.","authors":"Lei Sun, Jinwen Luan, Jinbiao Wang, Xiaoli Li, Wenqian Zhang, Xiaohui Ji, Longhua Liu, Ru Wang, Bingxiang Xu","doi":"10.1016/j.jshs.2024.100992","DOIUrl":"10.1016/j.jshs.2024.100992","url":null,"abstract":"<p><strong>Background: </strong>Physical activity can regulate and affect gene expression in multiple tissues and cells. Recently, with the development of next-generation sequencing, a large number of RNA-sequencing (RNA-seq)-based gene expression profiles about physical activity have been shared in public resources; however, they are poorly curated and underutilized. To tackle this problem, we developed a data atlas of such data through comprehensive data collection, curation, and organization.</p><p><strong>Methods: </strong>The data atlas, termed gene expression profiles of RNA-seq-based exercise responses (GEPREP), was built on a comprehensive collection of high-quality RNA-seq data on exercise responses. The metadata of each sample were manually curated. Data were uniformly processed and batch effects corrected. All the information was well organized in an easy-to-use website for free search, visualization, and download.</p><p><strong>Results: </strong>GEPREP now includes 69 RNA-seq datasets of pre- and post-exercise, comprising 26 human datasets (1120 samples) and 43 mouse datasets (1006 samples). Specifically, there were 977 (87.2 %) human samples of skeletal muscle and 143 (12.8 %) human samples of blood. There were also samples across 9 mice tissues with skeletal muscle (359, 35.7 %) and brain (280, 27.8 %) accounting for the main fractions. Metadata-including subject, exercise interventions, sampling sites, and post-processing methods-are also included. The metadata and gene expression profiles are freely accessible at http://www.geprep.org.cn/.</p><p><strong>Conclusion: </strong>GEPREP is a comprehensive data atlas of RNA-seq-based gene expression profiles responding to exercise. With its reliable annotations and user-friendly interfaces, it has the potential to deepen our understanding of exercise physiology.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"100992"},"PeriodicalIF":10.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863345/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142330552","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Can exercise kill tumors?","authors":"Abel Plaza-Florido, Alejandro Santos-Lozano, Natalia Yanguas-Casás, Tomàs Pinós, Carmen Fiuza-Luces, Alejandro Lucia","doi":"10.1016/j.jshs.2024.101001","DOIUrl":"10.1016/j.jshs.2024.101001","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"101001"},"PeriodicalIF":10.3,"publicationDate":"2025-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11863315/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}