John W Orchard, Ebonie Rio, Kay M Crossley, Jessica J Orchard, Margo Mountjoy
{"title":"Orchard Sports Injury and Illness Classification System (OSIICS) Version 15.","authors":"John W Orchard, Ebonie Rio, Kay M Crossley, Jessica J Orchard, Margo Mountjoy","doi":"10.1016/j.jshs.2024.03.004","DOIUrl":"10.1016/j.jshs.2024.03.004","url":null,"abstract":"<p><strong>Background: </strong>Sports medicine (injury and illnesses) requires distinct coding systems because the International Classification of Diseases is insufficient for sports medicine coding. The Orchard Sports Injury and Illness Classification System (OSIICS) is one of two sports medicine coding systems recommended by the International Olympic Committee. Regular updates of coding systems are required.</p><p><strong>Methods: </strong>For Version 15, updates for mental health conditions in athletes, sports cardiology, concussion sub-types, infectious diseases, and skin and eye conditions were considered particularly important.</p><p><strong>Results: </strong>Recommended codes were added from a recent International Olympic Committee consensus statement on mental health conditions in athletes. Two landmark sports cardiology papers were used to update a more comprehensive list of sports cardiology codes. Rugby union protocols on head injury assessment were used to create additional concussion codes.</p><p><strong>Conclusion: </strong>It is planned that OSIICS Version 15 will be translated into multiple new languages in a timely fashion to facilitate international accessibility. The large number of recently published sport-specific and discipline-specific consensus statements on athlete surveillance warrant regular updating of OSIICS.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"599-604"},"PeriodicalIF":11.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184301/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Hugo de Luca Corrêa, Lysleine Alves Deus, Dahan da Cunha Nascimento, Nicholas Rolnick, Rodrigo Vanerson Passos Neves, Andrea Lucena Reis, Thais Branquinho de Araújo, Carmen Tzanno-Martins, Fernanda Silveira Tavares, Luiz Sinésio Silva Neto, Cláudio Avelino Rodrigues Santos, Paolo Lucas Rodrigues-Silva, Fernando Honorato Souza, Vitória Marra da Motta Vilalva Mestrinho, Rafael Lavarini Dos Santos, Rosangela Vieira Andrade, Jonato Prestes, Thiago Dos Santos Rosa
{"title":"Concerns about the application of resistance exercise with blood-flow restriction and thrombosis risk in hemodialysis patients.","authors":"Hugo de Luca Corrêa, Lysleine Alves Deus, Dahan da Cunha Nascimento, Nicholas Rolnick, Rodrigo Vanerson Passos Neves, Andrea Lucena Reis, Thais Branquinho de Araújo, Carmen Tzanno-Martins, Fernanda Silveira Tavares, Luiz Sinésio Silva Neto, Cláudio Avelino Rodrigues Santos, Paolo Lucas Rodrigues-Silva, Fernando Honorato Souza, Vitória Marra da Motta Vilalva Mestrinho, Rafael Lavarini Dos Santos, Rosangela Vieira Andrade, Jonato Prestes, Thiago Dos Santos Rosa","doi":"10.1016/j.jshs.2024.02.006","DOIUrl":"10.1016/j.jshs.2024.02.006","url":null,"abstract":"<p><strong>Background: </strong>Hemodialysis (HD) per se is a risk factor for thrombosis. Considering the growing body of evidence on blood-flow restriction (BFR) exercise in HD patients, identification of possible risk factors related to the prothrombotic agent D-dimer is required for the safety and feasibility of this training model. The aim of the present study was to identify risk factors associated with higher D-dimer levels and to determine the acute effect of resistance exercise (RE) with BFR on this molecule.</p><p><strong>Methods: </strong>Two hundred and six HD patients volunteered for this study (all with a glomerular filtration rate of <15 mL/min/1.73 m<sup>2</sup>). The RE + BFR session consisted of 50% arterial occlusion pressure during 50 min sessions of HD (intradialytic exercise). RE repetitions included concentric and eccentric lifting phases (each lasting 2 s) and were supervised by a strength and conditioning specialist.</p><p><strong>Results: </strong>Several variables were associated with elevated levels of D-dimer, including higher blood glucose, citrate use, recent cardiovascular events, recent intercurrents, higher inflammatory status, catheter as vascular access, older patients (>70 years old), and HD vintage. Furthermore, RE + BFR significantly increases D-dimer after 4 h. Patients with borderline baseline D-dimer levels (400-490 ng/mL) displayed increased risk of elevating D-dimer over the normal range (≥500 ng/mL).</p><p><strong>Conclusion: </strong>These results identified factors associated with a heightened prothrombotic state and may assist in the screening process for HD patients who wish to undergo RE + BFR. D-dimer and/or other fibrinolysis factors should be assessed at baseline and throughout the protocol as a precautionary measure to maximize safety during RE + BFR.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"548-558"},"PeriodicalIF":11.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184314/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Soleus arthrogenic muscle inhibition following acute lateral ankle sprain correlates with symptoms and ankle disability but not with postural control.","authors":"Kyung-Min Kim, Joo-Sung Kim, Alan R Needle","doi":"10.1016/j.jshs.2024.02.005","DOIUrl":"10.1016/j.jshs.2024.02.005","url":null,"abstract":"<p><strong>Background: </strong>Acute lateral ankle sprains (ALAS) are associated with long-term impairments and instability tied to altered neural excitability. Arthrogenic muscle inhibition (AMI) has been observed in this population; however, relationships with injury-related impairments are unclear, potentially due to the resting, prone position in which AMI is typically measured. Assessing AMI during bipedal stance may provide a better understanding of this relationship.</p><p><strong>Methods: </strong>AMI was assessed in 38 young adults (19 ALAS within 72 h of injury: 10 males, 21.4 ± 2.7 years; 19 healthy controls: 10 males, 21.9 ± 2.2 years; mean ± SD) using the Hoffmann reflex (H-reflex) during bipedal stance. Electrical stimulation was administered to identify the maximal H-reflex (H<sub>max</sub>) and maximal motor response (M<sub>max</sub>) from the soleus, fibularis longus, and tibialis anterior muscles. The primary outcome measure was the H<sub>max</sub>/M<sub>max</sub> ratio. Secondary outcomes included acute symptoms (pain and swelling), postural control during bipedal stance, and self-reported function.</p><p><strong>Results: </strong>No significant group-by-limb interactions were observed for any muscle. However, a significant group main effect was observed in the soleus muscle (F<sub>(1,35)</sub> = 6.82, p = 0.013), indicating significantly lower H<sub>max</sub>/M<sub>max</sub> ratios following ALAS (0.38 ± 0.20) compared to healthy controls (0.53 ± 0.16). Furthermore, lower H<sub>max</sub>/M<sub>max</sub> ratios in the soleus significantly correlated with acute symptoms and self-reported function but not with postural control.</p><p><strong>Conclusion: </strong>This study supports previous evidence of AMI in patients with ALAS, providing insight into neurophysiologic impacts of musculoskeletal injury. Our results suggest that assessing AMI in a standing position following acute injury may provide valuable insight into how AMI develops and guide potential therapeutic options to curb and offset the formation of joint instability.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"559-568"},"PeriodicalIF":11.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184308/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140013528","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Silvio Maltagliati, Philippe Sarrazin, Layan Fessler, Maël Lebreton, Boris Cheval
{"title":"Why people should run after positive affective experiences instead of health benefits.","authors":"Silvio Maltagliati, Philippe Sarrazin, Layan Fessler, Maël Lebreton, Boris Cheval","doi":"10.1016/j.jshs.2022.10.005","DOIUrl":"10.1016/j.jshs.2022.10.005","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"445-450"},"PeriodicalIF":9.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184383/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10351153","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Diego Orcioli-Silva, Victor Spiandor Beretta, Paulo Cezar Rocha Santos, Felipe Marroni Rasteiro, Anita Brum Marostegan, Rodrigo Vitório, Claudio Alexandre Gobatto, Fúlvia Barros Manchado-Gobatto
{"title":"Cerebral and muscle tissue oxygenation during exercise in healthy adults: A systematic review.","authors":"Diego Orcioli-Silva, Victor Spiandor Beretta, Paulo Cezar Rocha Santos, Felipe Marroni Rasteiro, Anita Brum Marostegan, Rodrigo Vitório, Claudio Alexandre Gobatto, Fúlvia Barros Manchado-Gobatto","doi":"10.1016/j.jshs.2024.03.003","DOIUrl":"10.1016/j.jshs.2024.03.003","url":null,"abstract":"<p><strong>Background: </strong>Near-infrared spectroscopy (NIRS) technology has allowed for the measurement of cerebral and skeletal muscle oxygenation simultaneously during exercise. Since this technology has been growing and is now successfully used in laboratory and sports settings, this systematic review aimed to synthesize the evidence and enhance an integrative understanding of blood flow adjustments and oxygen (O<sub>2</sub>) changes (i.e., the balance between O<sub>2</sub> delivery and O<sub>2</sub> consumption) within the cerebral and muscle systems during exercise.</p><p><strong>Methods: </strong>A systematic review was conducted using PubMed, Embase, Scopus, and Web of Science databases to search for relevant studies that simultaneously investigated cerebral and muscle hemodynamic changes using the near-infrared spectroscopy system during exercise. This review considered manuscripts written in English and available before February 9, 2023. Each step of screening involved evaluation by 2 independent authors, with disagreements resolved by a third author. The Joanna Briggs Institute Critical Appraisal Checklist was used to assess the methodological quality of the studies.</p><p><strong>Results: </strong>Twenty studies were included, of which 80% had good methodological quality, and involved 290 young or middle-aged adults. Different types of exercises were used to assess cerebral and muscle hemodynamic changes, such as cycling (n = 11), treadmill (n = 1), knee extension (n = 5), isometric contraction of biceps brachii (n = 3), and duet swim routines (n = 1). The cerebral hemodynamics analysis was focused on the frontal cortex (n = 20), while in the muscle, the analysis involved vastus lateralis (n = 18), gastrocnemius (n = 3), biceps brachii (n = 5), deltoid (n = 1), and intercostal muscle (n = 1). Overall, muscle deoxygenation increases during exercise, reaching a plateau in voluntary exhaustion, while in the brain, oxyhemoglobin concentration increases with exercise intensity, reaching a plateau or declining at the exhaustion point.</p><p><strong>Conclusion: </strong>Muscle and cerebral oxygenation respond differently to exercise, with muscle increasing O<sub>2</sub> utilization and cerebral tissue increasing O<sub>2</sub> delivery during exercise. However, at the exhaustion point, both muscle and cerebral oxygenation become compromised. This is characterized by a reduction in blood flow and a decrease in O<sub>2</sub> extraction in the muscle, while in the brain, oxygenation reaches a plateau or decline, potentially resulting in motor failure during exercise.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"459-471"},"PeriodicalIF":9.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184313/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140094970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The emerging role of exercise as a cancer treatment.","authors":"Kerry S Courneya","doi":"10.1016/j.jshs.2023.03.006","DOIUrl":"10.1016/j.jshs.2023.03.006","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"443-444"},"PeriodicalIF":9.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"9375543","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Could near infrared spectroscopy be the new weapon in our understanding of the cerebral and muscle microvascular oxygen demand during exercise?","authors":"Stéphane Perrey","doi":"10.1016/j.jshs.2024.03.006","DOIUrl":"10.1016/j.jshs.2024.03.006","url":null,"abstract":"","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"457-458"},"PeriodicalIF":11.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184300/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jacqueline Josee van Ierssel, Olivia Galea, Kirsten Holte, Caroline Luszawski, Elizabeth Jenkins, Jennifer O'Neil, Carolyn A Emery, Rebekah Mannix, Kathryn Schneider, Keith Owen Yeates, Roger Zemek
{"title":"How completely are randomized controlled trials of non-pharmacological interventions following concussion reported? A systematic review.","authors":"Jacqueline Josee van Ierssel, Olivia Galea, Kirsten Holte, Caroline Luszawski, Elizabeth Jenkins, Jennifer O'Neil, Carolyn A Emery, Rebekah Mannix, Kathryn Schneider, Keith Owen Yeates, Roger Zemek","doi":"10.1016/j.jshs.2023.08.003","DOIUrl":"10.1016/j.jshs.2023.08.003","url":null,"abstract":"<p><strong>Purpose: </strong>The study aimed to examine the reporting completeness of randomized controlled trials (RCTs) of non-pharmacological interventions following concussion.</p><p><strong>Methods: </strong>We searched MEDLINE, Embase, PsycInfo, CINAHL, and Web of Science up to May 2022. Two reviewers independently screened studies and assessed reporting completeness using the Template for Intervention Description and Replication (TIDieR), Consensus on Exercise Reporting Template (CERT), and international Consensus on Therapeutic Exercise aNd Training (i-CONTENT) checklists. Additional information was sought my study authors where reporting was incomplete. Risk of bias (ROB) was assessed with the Cochrane ROB-2 Tool. RCTs examining non-pharmacological interventions following concussion.</p><p><strong>Results: </strong>We included 89 RCTs (n = 53 high ROB) examining 11 different interventions for concussion: sub-symptom threshold aerobic exercise, cervicovestibular therapy, physical/cognitive rest, vision therapy, education, psychotherapy, hyperbaric oxygen therapy, transcranial magnetic stimulation, blue light therapy, osteopathic manipulation, and head/neck cooling. Median scores were: TIDieR 9/12 (75%; interquartile range (IQR) = 5; range: 5-12), CERT 17/19 (89%; IQR = 2; range: 10-19), and i-CONTENT 6/7 (86%; IQR = 1; range: 5-7). Percentage of studies completely reporting all items was TIDieR 35% (31/89), CERT 24% (5/21), and i-CONTENT 10% (2/21). Studies were more completely reported after publication of TIDieR (t<sub>87</sub> = 2.08; p = 0.04) and CERT (t<sub>19</sub> = 2.72; p = 0.01). Reporting completeness was not strongly associated with journal impact factor (TIDieR: r<sub>s</sub> = 0.27; p = 0.01; CERT: r<sub>s</sub> = -0.44; p = 0.06; i-CONTENT: r<sub>s</sub> = -0.17; p = 0.48) or ROB (TIDieR: r<sub>s</sub> = 0.11; p = 0.31; CERT: r<sub>s</sub> = 0.04; p = 0.86; i-CONTENT: r<sub>s</sub> = 0.12; p = 0.60).</p><p><strong>Conclusion: </strong>RCTs of non-pharmacological interventions following concussion demonstrate moderate to good reporting completeness, but are often missing key components, particularly modifications, motivational strategies, and qualified supervisor. Reporting completeness improved after TIDieR and CERT publication, but publication in highly cited journals and low ROB do not guarantee reporting completeness.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"537-547"},"PeriodicalIF":9.7,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11184319/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"10181279","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mona Kotewitsch, Melina Heimer, Boris Schmitz, Frank C Mooren
{"title":"Non-coding RNAs in exercise immunology: A systematic review.","authors":"Mona Kotewitsch, Melina Heimer, Boris Schmitz, Frank C Mooren","doi":"10.1016/j.jshs.2023.11.001","DOIUrl":"10.1016/j.jshs.2023.11.001","url":null,"abstract":"<p><p>Regular physical exercise has been recognized as a potent modulator of immune function, with its effects including enhanced immune surveillance, reduced inflammation, and improved overall health. While strong evidence exists that physical exercise affects the specific expression and activity of non-coding RNAs (ncRNAs) also involved in immune system regulation, heterogeneity in individual study designs and analyzed exercise protocols exists, and a condensed list of functional, exercise-dependent ncRNAs with known targets in the immune system is missing from the literature. A systematic review and qualitative analysis was used to identify and categorize ncRNAs participating in immune modulation by physical exercise. Two combined approaches were used: (a) a systematic literature search for \"ncRNA and exercise immunology\", (b) and a database search for microRNAs (miRNAs) (miRTarBase and DIANA-Tarbase v8) aligned with known target genes in the immune system based on the Reactome database, combined with a systematic literature search for \"ncRNA and exercise\". Literature searches were based on PubMed, Web of Science, and SPORTDiscus; and miRNA databases were filtered for targets validated by in vitro experimental data. Studies were eligible if they reported on exercise-based interventions in healthy humans. After duplicate removal, 95 studies were included reporting on 164 miRNAs, which were used for the qualitative synthesis. Six studies reporting on long-noncoding RNAs (lncRNAs) or circular RNAs were also identified. Results were analyzed using ordering tables that included exercise modality (endurance/resistance exercise), acute or chronic interventions, as well as the consistency in reported change between studies. Evaluation criteria were defined as \"validated\" with 100% of ≥3 independent studies showing identical direction of regulation, \"plausible\" (≥80%), or \"suggestive\" (≥70%). For resistance exercise, upregulation of miR-206 was validated while downregulation of miR-133a appeared plausible. For endurance exercise, 15 miRNAs were categorized as validated, with 12 miRNAs being consistently elevated and 3 miRNAs being downregulated, most of them after acute exercise training. In conclusion, our approach provides evidence that miRNAs play a major role in exercise-induced effects on the innate and adaptive immune system by targeting different pathways affecting immune cell distribution, function, and trafficking as well as production of (anti-)inflammatory cytokines. miRNAs miR-15, miR-29c, miR-30a, miR-142/3, miR-181a, and miR-338 emerged as key players in mediating the immunomodulatory effects of exercise predominantly after acute bouts of endurance exercise.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"311-338"},"PeriodicalIF":11.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11116971/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"71487816","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Carolette Snyders, Marlise Dyer, Nicola Sewry, Esme Jordaan, Martin Schwellnus
{"title":"Increased number of symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged time to return to full sports performance-AWARE VIII.","authors":"Carolette Snyders, Marlise Dyer, Nicola Sewry, Esme Jordaan, Martin Schwellnus","doi":"10.1016/j.jshs.2023.10.005","DOIUrl":"10.1016/j.jshs.2023.10.005","url":null,"abstract":"<p><strong>Purpose: </strong>The aim of the study was to identify factors associated with prolonged time to return to full performance (RTFP) in athletes with recent severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.</p><p><strong>Methods: </strong>Prospective cohort study with cross sectional analysis. A total of 84 athletes with confirmed SARS-CoV-2 infection assessed at a coronavirus disease 2019 recovery clinic gave a history of age, sex, type/level of sport, co-morbidities, pre-infection training hours, and 26 acute SARS-CoV-2 symptoms from 3 categories (\"nose and throat\", \"chest and neck\", and \"whole body\"/systemic). Data on days to RTFP were obtained by structured interviews. Factors associated with RTFP were demographics, sport participation, history of co-morbidities, pre-infection training history, and acute symptoms (type, number). Outcomes were: (a) days to RTFP (median, interquartile range (IQR)) in asymptomatic (n = 7) and symptomatic athletes (n = 77), and (b) hazard ratios (HRs; 95% confidence interval) for symptomatic athletes with vs. without a factor (univariate, multiple models). HR < 1 was predictive of higher percentage chance of prolonged RTFP. Significance was p < 0.05.</p><p><strong>Results: </strong>Days to RTFP were 30 days (IQR: 23-40) for asymptomatic and 64 days (IQR: 42-91) for symptomatic participants (p > 0.05). Factors associated with prolonged RTFP (univariate models) were: females (HR = 0.57; p = 0.014), endurance athletes (HR = 0.41; p < 0.0001), co-morbidity number (HR = 0.75; p = 0.001), and respiratory disease history (HR = 0.54; p = 0.026). In symptomatic athletes, prolonged RTFP (multiple models) was significantly associated with increased \"chest and neck\" (HR = 0.85; p = 0.017) and \"nose and throat\" (HR = 0.84; p = 0.013) symptoms, but the association was more profound between prolonged RFTP and increased total number of \"all symptoms\" (HR = 0.91; p = 0.001) and \"whole body\"/systemic (HR = 0.82; p = 0.007) symptoms.</p><p><strong>Conclusion: </strong>A larger number of total symptoms and specifically \"whole body\"/systemic symptoms during the acute phase of SARS-CoV-2 infection in athletes is associated with prolonged RTFP.</p>","PeriodicalId":48897,"journal":{"name":"Journal of Sport and Health Science","volume":" ","pages":"280-287"},"PeriodicalIF":11.7,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11116957/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49693308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":1,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}