Annals of Global Health最新文献

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Advancing Gender Equality in Healthcare Leadership: Protocol to Co-Design and Evaluate a Leadership and Mentoring Intervention in Tanzania. 促进医疗保健领导中的性别平等:在坦桑尼亚共同设计和评估领导力和指导干预措施的协议》(Protocol to Co-Design and Evaluate a Leadership and Mentoring Intervention in Tanzania)。
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-03-28 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4374
Doreen Mucheru, Henry Mollel, Brynne Gilmore, Anosisye Kesale, Eilish McAuliffe
{"title":"Advancing Gender Equality in Healthcare Leadership: Protocol to Co-Design and Evaluate a Leadership and Mentoring Intervention in Tanzania.","authors":"Doreen Mucheru, Henry Mollel, Brynne Gilmore, Anosisye Kesale, Eilish McAuliffe","doi":"10.5334/aogh.4374","DOIUrl":"10.5334/aogh.4374","url":null,"abstract":"<p><strong>Background: </strong>Women constitute almost two thirds of the health and social workforce. Yet, the proportion of women in decision-making positions remains significantly low leading to gender inequities in access to and appropriateness of healthcare. Several barriers which limit women's advancement to leadership positions have been documented and they generally constitute of gender stereotypes, discrimination and inhibiting systems; these hinderances are compounded by intersection with other social identities. Amelioration of the barriers has the potential to enhance women's participation in leadership and strengthen the existing health systems.</p><p><strong>Objective: </strong>This protocol describes a proposed study aimed at addressing the organisational and individual barriers to the advancement of women to leadership positions in the Tanzanian health sector, and to evaluate the influence on leadership competencies and career advancement actions of the female health workforce.</p><p><strong>Method: </strong>The study utilises a gender transformative approach, co-design and implementation science in the development and integration of a leadership and mentorship intervention for women in the Tanzanian health context. The key steps in this research include quantifying the gender ratio in healthcare leadership; identifying the individual and organisational barriers to women's leadership; reviewing existing leadership, mentorship and career advancement interventions for women; recruiting programme participants for a leadership and mentorship programme; running a co-design workshop with programme participants and stakeholders; implementing a leadership and mentorship programme; and conducting a collaborative evaluation and lessons learnt.</p><p><strong>Conclusions: </strong>This research underscores the notion that progression towards gender equality in healthcare leadership is attained by fashioning a system that supports the advancement of women. We also argue that one of the pivotal indicators of progress towards the gender equality sustainable development goal is the number of women in senior and middle management positions, which we hope to further through this research.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-03-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976988/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Characterizing Mobility and its Association with HIV Outcomes in Refugee Settlements in Uganda. 乌干达难民定居点的流动性特征及其与艾滋病结果的关联。
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-03-25 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4367
Robin E Klabbers, Canada Parrish, Patient Iraguha, Marcel Kambale Ntuyenabo, Scovia Ajidiru, Valentine Nshimiyimana, Kampire Caroline, Zikama Faustin, Elinor M Sveum, Timothy R Muwonge, Kelli N O'Laughlin
{"title":"Characterizing Mobility and its Association with HIV Outcomes in Refugee Settlements in Uganda.","authors":"Robin E Klabbers, Canada Parrish, Patient Iraguha, Marcel Kambale Ntuyenabo, Scovia Ajidiru, Valentine Nshimiyimana, Kampire Caroline, Zikama Faustin, Elinor M Sveum, Timothy R Muwonge, Kelli N O'Laughlin","doi":"10.5334/aogh.4367","DOIUrl":"10.5334/aogh.4367","url":null,"abstract":"<p><strong>Background: </strong>A better understanding of refugee mobility is needed to optimize HIV care in refugee settlements.</p><p><strong>Objectives: </strong>We aimed to characterize mobility patterns among people living with HIV in refugee settlements in Uganda and evaluate the association between mobility and retention in HIV care.</p><p><strong>Methods: </strong>Refugees and Ugandan nationals accessing HIV services at seven health centers in refugee settlements across Uganda, with access to a phone, were recruited and followed for six months. Participants received an intake survey and monthly phone surveys on mobility and HIV. Clinic visit and viral suppression data were extracted from clinic registers. Mobility and HIV data were presented descriptively, and an alluvial plot was generated characterizing mobility for participants' most recent trip. Bivariate Poisson regression models were used to describe the associations between long-term mobility (≥1 continuous month away in the past year) and demographic characteristics, retention (≥1 clinic visit/6 months) and long-term mobility, and retention and general mobility (during any follow-up month: ≥2 trips, travel outside the district or further, or spending >1-2 weeks (8-14 nights) away).</p><p><strong>Findings: </strong>Mobility data were provided by 479 participants. At baseline, 67 participants (14%) were considered long-term mobile. Male sex was associated with an increased probability of long-term mobility (RR 2.02; 95%CI: 1.30-3.14, p < 0.01). In follow-up, 185 participants (60% of respondents) were considered generally mobile. Reasons for travel included obtaining food or supporting farming activities (45% of trips) and work or trade (33% of trips). Retention in HIV care was found for 417 (87%) participants. Long-term mobility was associated with a 14% (RR 0.86; 95%CI: 0.75-0.98) lower likelihood of retention (p = 0.03).</p><p><strong>Conclusions: </strong>Refugees and Ugandan nationals accessing HIV care in refugee settlements frequently travel to support their survival needs. Mobility is associated with inferior retention and should be considered in interventions to optimize HIV care.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10976981/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319598","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evidence-based Decision Making: Infectious Disease Modeling Training for Policymakers in East Africa. 基于证据的决策:东非决策者传染病建模培训。
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-03-22 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4383
Sylvia K Ofori, Emmanuelle A Dankwa, Emmanuel Ngwakongnwi, Alemayehu Amberbir, Abebe Bekele, Megan B Murray, Yonatan H Grad, Caroline O Buckee, Bethany L Hedt-Gauthier
{"title":"Evidence-based Decision Making: Infectious Disease Modeling Training for Policymakers in East Africa.","authors":"Sylvia K Ofori, Emmanuelle A Dankwa, Emmanuel Ngwakongnwi, Alemayehu Amberbir, Abebe Bekele, Megan B Murray, Yonatan H Grad, Caroline O Buckee, Bethany L Hedt-Gauthier","doi":"10.5334/aogh.4383","DOIUrl":"10.5334/aogh.4383","url":null,"abstract":"<p><strong>Background: </strong>Mathematical modeling of infectious diseases is an important decision-making tool for outbreak control. However, in Africa, limited expertise reduces the use and impact of these tools on policy. Therefore, there is a need to build capacity in Africa for the use of mathematical modeling to inform policy. Here we describe our experience implementing a mathematical modeling training program for public health professionals in East Africa.</p><p><strong>Methods: </strong>We used a deliverable-driven and learning-by-doing model to introduce trainees to the mathematical modeling of infectious diseases. The training comprised two two-week in-person sessions and a practicum where trainees received intensive mentorship. Trainees evaluated the content and structure of the course at the end of each week, and this feedback informed the strategy for subsequent weeks.</p><p><strong>Findings: </strong>Out of 875 applications from 38 countries, we selected ten trainees from three countries - Rwanda (6), Kenya (2), and Uganda (2) - with guidance from an advisory committee. Nine trainees were based at government institutions and one at an academic organization. Participants gained skills in developing models to answer questions of interest and critically appraising modeling studies. At the end of the training, trainees prepared policy briefs summarizing their modeling study findings. These were presented at a dissemination event to policymakers, researchers, and program managers. All trainees indicated they would recommend the course to colleagues and rated the quality of the training with a median score of 9/10.</p><p><strong>Conclusions: </strong>Mathematical modeling training programs for public health professionals in Africa can be an effective tool for research capacity building and policy support to mitigate infectious disease burden and forecast resources. Overall, the course was successful, owing to a combination of factors, including institutional support, trainees' commitment, intensive mentorship, a diverse trainee pool, and regular evaluations.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-03-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10959131/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140207991","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Adapting an Intervention to Improve Acute Myocardial Infarction Care in Tanzania: Co-Design of the MIMIC Intervention. 调整干预措施,改善坦桑尼亚的急性心肌梗死护理:共同设计 MIMIC 干预方案。
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-03-13 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4361
Julian T Hertz, Kristen Stark, Francis M Sakita, Jerome J Mlangi, Godfrey L Kweka, Sainikitha Prattipati, Frida Shayo, Vivian Kaboigora, Julius Mtui, Manji N Isack, Esther M Kindishe, Dotto J Ngelengi, Alexander T Limkakeng, Nathan M Thielman, Gerald S Bloomfield, Janet P Bettger, Tumsifu G Tarimo
{"title":"Adapting an Intervention to Improve Acute Myocardial Infarction Care in Tanzania: Co-Design of the MIMIC Intervention.","authors":"Julian T Hertz, Kristen Stark, Francis M Sakita, Jerome J Mlangi, Godfrey L Kweka, Sainikitha Prattipati, Frida Shayo, Vivian Kaboigora, Julius Mtui, Manji N Isack, Esther M Kindishe, Dotto J Ngelengi, Alexander T Limkakeng, Nathan M Thielman, Gerald S Bloomfield, Janet P Bettger, Tumsifu G Tarimo","doi":"10.5334/aogh.4361","DOIUrl":"10.5334/aogh.4361","url":null,"abstract":"<p><strong>Background: </strong>Uptake of evidence-based care for acute myocardial infarction (AMI) is suboptimal in Tanzania, but there are currently no published interventions to improve AMI care in sub-Saharan Africa.</p><p><strong>Objectives: </strong>Co-design a quality improvement intervention for AMI care tailored to local contextual factors.</p><p><strong>Methods: </strong>An interdisciplinary design team consisting of 20 physicians, nurses, implementation scientists, and administrators met from June 2022 through August 2023. Half of the design team consisted of representatives from the target audience, emergency department physicians and nurses at a referral hospital in northern Tanzania. The design team reviewed multiple published quality improvement interventions focusing on ED-based AMI care. After selecting a multicomponent intervention to improve AMI care in Brazil (BRIDGE-ACS), the design team used the ADAPT-ITT framework to adapt the intervention to the local context.</p><p><strong>Findings: </strong>The design team audited current AMI care processes at the study hospital and reviewed qualitative data regarding barriers to care. Multiple adaptations were made to the original BRIDGE-ACS intervention to suit the local context, including re-designing the physician reminder system and adding patient educational materials. Additional feedback was sought from topical experts, including patients with AMI. Draft intervention materials were iteratively refined in response to feedback from experts and the design team. The finalized intervention, Multicomponent Intervention to Improve Myocardial Infarction Care in Tanzania (MIMIC), consisted of five core components: physician reminders, pocket cards, champions, provider training, and patient education.</p><p><strong>Conclusion: </strong>MIMIC is the first locally tailored intervention to improve AMI care in sub-Saharan Africa. Future studies will evaluate implementation outcomes and efficacy.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-03-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10941691/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Mapping Human Resources to Guide Ophthalmology Capacity-Building Projects in Honduras: Sub-national Analyses of Physician Distribution and Surgical Practices. 绘制人力资源图,指导洪都拉斯眼科能力建设项目:国家以下各级医生分布和手术实践分析。
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-03-11 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4384
Rocio Banegas, Luis Rojas, Mariela Castillo, Luis Lagos, Kevin Barber, Britton Ethridge, Sara O'Connor
{"title":"Mapping Human Resources to Guide Ophthalmology Capacity-Building Projects in Honduras: Sub-national Analyses of Physician Distribution and Surgical Practices.","authors":"Rocio Banegas, Luis Rojas, Mariela Castillo, Luis Lagos, Kevin Barber, Britton Ethridge, Sara O'Connor","doi":"10.5334/aogh.4384","DOIUrl":"10.5334/aogh.4384","url":null,"abstract":"<p><strong>Objective: </strong>To map ophthalmologist locations and surgical practices as they vary sub-nationally within Honduras to maximize the impact of efforts to develop cataract surgical capacity.</p><p><strong>Methods: </strong>An anonymous survey was sent to all Honduran ophthalmologists with questions on surgical volume, department-level location, type of facility in which they work, surgical methods, and age. Surgical volume, population, and poverty data sourced through the Oxford Poverty Human Development Initiative were mapped at the department level, and cataract surgical rates (CSR; surgeries per million population per year) were calculated and mapped.</p><p><strong>Results: </strong>Sixty-one of the 102 Honduran ophthalmologists contacted responded. Of those, 85% perform cataract surgery, and 49% work at least part time in a non-profit or governmental facility. Honduras has fewer surgical ophthalmologists per million than the global average, and though national CSR appears to be increasing, it varies significantly between departments. The correlation between CSR and poverty is complex, and outliers provide valuable insights.</p><p><strong>Conclusion: </strong>Mapping ophthalmological surgical practices as they relate to population and poverty at a sub-national level provides important insights into geographic trends in the need for and access to eye care. Such insights can be used to guide efficient and effective development of cataract surgical capacity.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10941696/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140144414","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Learning from the End of the Public-Private Partnership for Lesotho’s National Referral Hospital Network 从莱索托国家转诊医院网络公私合作伙伴关系的终结中学习
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-03-07 DOI: 10.5334/aogh.4377
Chelsea M. McGuire, Jeanette L. Kaiser, Taryn Vian, E. Nkabane-Nkholongo, Tshema Nash, Brian W. Jack, Nancy A. Scott
{"title":"Learning from the End of the Public-Private Partnership for Lesotho’s National Referral Hospital Network","authors":"Chelsea M. McGuire, Jeanette L. Kaiser, Taryn Vian, E. Nkabane-Nkholongo, Tshema Nash, Brian W. Jack, Nancy A. Scott","doi":"10.5334/aogh.4377","DOIUrl":"https://doi.org/10.5334/aogh.4377","url":null,"abstract":"Background: Public-private partnerships (PPP) are one strategy to finance and deliver healthcare in lower-resourced settings. Lesotho’s Queen ‘Mamohato Memorial Hospital Integrated Network (QMMH-IN) was sub-Saharan Africa’s first and largest integrated healthcare PPP. Objective: We assessed successes and challenges to performance of the QMMH-IN PPP. Methods: We conducted 26 semi-structured interviews among QMMH-IN executive leadership and staff in early 2020. Questions were guided by the WHO Health System Building Blocks Framework. We conducted a thematic analysis. Findings: Facilitators of performance included: 1) PPP leadership commitment to quality improvement supported by protocols, monitoring, and actions; 2) high levels of accountability and discipline; and 3) well-functioning infrastructure, core systems, workflows, and internal referral network. Barriers to performance included: 1) human resource management challenges and 2) broader health system and referral network limitations. Respondents anticipated the collapse of the PPP and suggested better investing in training incoming managerial staff, improving staffing, and expanding QMMH-IN’s role as a training facility. Conclusions: The PPP contract was terminated approximately five years before its anticipated end date; in mid-2021 the government of Lesotho assumed management of QMMH-IN. Going forward, the Lesotho government and others making strategic planning decisions should consider fostering a culture of quality improvement and accountability; ensuring sustained investments in human resource management; and allocating resources in a way that recognizes the interdependency of healthcare facilities and overall system strengthening. Contracts for integrated healthcare PPPs should be flexible to respond to changing external conditions and include provisions to invest in people as substantively as infrastructure, equipment, and core systems over the full length of the PPP. Healthcare PPPs, especially in lower-resource settings, should be developed with a strong understanding of their role in the broader health system and be implemented in conjunction with efforts to ensure and sustain adequate capacity and resources throughout the health system.","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-03-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140077334","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
National Non-Communicable Diseases Conferences- A Platform to Inform Policies and Practices in Tanzania 全国非传染性疾病会议--为坦桑尼亚的政策和实践提供信息的平台
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-03-04 DOI: 10.5334/aogh.4112
D. Amani, H. Ndumwa, Jackline E Ngowi, B. Njiro, Castory Munishi, Erick A Mboya, Doreen Mloka, A. Kikula, Emmanuel Balandya, Paschal Ruggajo, A. Kessy, Emilia Kitambala, N. Kapologwe, J. Kengia, James Kiologwe, O. Ubuguyu, Bakari Salum, A. Kamuhabwa, K. Ramaiya, B. Sunguya
{"title":"National Non-Communicable Diseases Conferences- A Platform to Inform Policies and Practices in Tanzania","authors":"D. Amani, H. Ndumwa, Jackline E Ngowi, B. Njiro, Castory Munishi, Erick A Mboya, Doreen Mloka, A. Kikula, Emmanuel Balandya, Paschal Ruggajo, A. Kessy, Emilia Kitambala, N. Kapologwe, J. Kengia, James Kiologwe, O. Ubuguyu, Bakari Salum, A. Kamuhabwa, K. Ramaiya, B. Sunguya","doi":"10.5334/aogh.4112","DOIUrl":"https://doi.org/10.5334/aogh.4112","url":null,"abstract":"Background: Non-communicable diseases (NCDs) arise from diverse risk factors with differences in the contexts and variabilities in regions and countries. Addressing such a complex challenge requires local evidence. Tanzania has been convening stakeholders every year to disseminate and discuss scientific evidence, policies, and implementation gaps, to inform policy makers in NCDs responses. This paper documents these dissemination efforts and how they have influenced NCDs response and landscape in Tanzania and the region. Methods: Desk review was conducted through available MOH and conference organizers’ documents. It had both quantitative and qualitative data. The review included reports of the four NCDs conferences, conference organization, and conduct processes. In addition, themes of the conferences, submitted abstracts, and presentations were reviewed. Narrative synthesis was conducted to address the objectives. Recommendations emanated from the conference and policy uptake were reviewed and discussed to determine the impact of the dissemination. Findings: Since 2019, four theme-specific conferences were organized. This report includes evidence from four conferences. The conferences convened researchers and scientists from research and training institutions, implementers, government agencies, and legislators in Tanzania and other countries within and outside Africa. Four hundred and thirty-five abstracts were presented covering 14 sub-themes on health system improvements, financing, governance, prevention intervention, and the role of innovation and technology. The conferences have had a positive effect on governments’ response to NCDs, including health care financing, NCDs research agenda, and universal health coverage. Conclusion: The National NCDs conferences have provided suitable platforms where stakeholders can share, discuss, and recommend vital strategies for addressing the burden of NCDs through informing policies and practices. Ensuring the engagement of the right stakeholders, as well as the uptake and utilization of the recommendations from these platforms, remains crucial for addressing the observed epidemiological transition in Tanzania and other countries with similar contexts.","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140079814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Wheel Replacing Pyramid: Better Paradigm Representing Totality of Evidence-Based Medicine. 轮子取代金字塔:更好地代表循证医学的整体范式。
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-02-29 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4341
Colleen Aldous, Barry M Dancis, Jerome Dancis, Philip R Oldfield
{"title":"Wheel Replacing Pyramid: Better Paradigm Representing Totality of Evidence-Based Medicine.","authors":"Colleen Aldous, Barry M Dancis, Jerome Dancis, Philip R Oldfield","doi":"10.5334/aogh.4341","DOIUrl":"10.5334/aogh.4341","url":null,"abstract":"<p><strong>Background: </strong>Evidence-based medicine (EBM), as originally conceived, used all types of peer-reviewed evidence to guide medical practice and decision-making. During the SARS-CoV-2 Coronavirus disease (COVID-19) pandemic, the standard usage of EBM, modeled by the Evidence-Based Medicine Pyramid, undermined EBM by incorrectly using pyramid levels to assign relative quality. The resulting pyramid-based thinking is biased against reports both in levels beneath randomized control trials (RCTs) and those omitted from the pyramid entirely. Thus, much of the evidence was ignored. Our desire for a more encompassing and effective medical decision-making process to apply to repurposed drugs led us to develop an alternative to the EBM Pyramid for EBM. Herein, we propose the totality of evidence (T-EBM) wheel.</p><p><strong>Objectives: </strong>To create an easily understood graphic that models EBM by incorporating all peer-reviewed evidence that applies to both new and repurposed medicines, and to demonstrate its potential utility using ivermectin as a case study.</p><p><strong>Methods: </strong>The graphics were produced using Microsoft Office Visio Professional 2003 except for part of the T-EBM wheel sunburst chart, which was produced using Microsoft 365 Excel. For the case study, PubMed® was used by searching for peer-reviewed reports containing \"ivermectin\" and either \"covid\" or \"sars\" in the title. Reports were filtered for those using ivermectin-based protocols in the treatment of COVID-19. The resulting 265 reports were evaluated for their study design types and treatment outcomes. The three-ringed graphical T-EBM wheel was composed of two inner rings showing all types of reports and an outer ring showing outcomes for each type.</p><p><strong>Findings-conclusions: </strong>The T-EBM wheel avoids the biases of the EBM Pyramid and includes all types of reports in the pyramid along with reports such as population and mechanistic studies. In both early and late stages of medical emergencies, pyramid-based thinking may overlook indications of efficacy in regions of the T-EBM wheel beyond RCTs. This is especially true when searching for ways to prevent and treat a novel disease with repurposed therapeutics before RCTs, safety assessments, and mechanisms of action of novel therapeutics are established. As such, T-EBM Wheels should replace the EBM Pyramids in medical decision-making and education. T-EBM Wheels can be expanded upon by implementing multiple outer rings, one for each different kind of outcome (efficacy, safety, etc.). A T-EBM Wheel can be created for any proprietary or generic medicine. The ivermectin (IVM) T-EBM Wheel displays the efficacy of IVM-based treatments of COVID-19 in a color-coded graphic, visualizing each type of evidence and the proportions of each of their outcomes (positive, inconclusive, negative).</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-02-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906340/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023037","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Self-Determination in Global Health Practices - Voices from the Global South. 全球卫生实践中的自决--来自全球南部的声音。
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-02-28 eCollection Date: 2024-01-01 DOI: 10.5334/aogh.4162
Maureen Kesande, Jane Jere, Sandra I McCoy, Abel Wilson Walekhwa, Bongekile Esther Nkosi-Mjadu, Eunice Ndzerem-Shang
{"title":"Self-Determination in Global Health Practices - Voices from the Global South.","authors":"Maureen Kesande, Jane Jere, Sandra I McCoy, Abel Wilson Walekhwa, Bongekile Esther Nkosi-Mjadu, Eunice Ndzerem-Shang","doi":"10.5334/aogh.4162","DOIUrl":"10.5334/aogh.4162","url":null,"abstract":"<p><p>Despite the commendable progress made in addressing global health challenges and threats such as child mortality, HIV/AIDS, and Tuberculosis, many global health organizations still exhibit a Global North supremacy attitude, evidenced by their choice of leaders and executors of global health initiatives in low- and middle-income countries (LMICs). While efforts by the Global North to support global health practice in LMICs have led to economic development and advancement in locally led research, current global health practices tend to focus solely on intervention outcomes, often neglecting important systemic factors such as intellectual property ownership, sustainability, diversification of leadership roles, and national capacity development. This has resulted in the implementation of practices and systems informed by high-income countries (HICs) to the detriment of knowledge systems in LMICs, as they are deprived of the opportunity to generate local solutions for local problems. From their unique position as international global health fellows located in different African countries and receiving graduate education from a HIC institution, the authors of this viewpoint article assess how HIC institutions can better support LMICs. The authors propose several strategies for achieving equitable global health practices; 1) allocating funding to improve academic and research infrastructures in LMICs; 2) encouraging effective partnerships and collaborations with Global South scientists who have lived experiences in LMICs; 3) reviewing the trade-related aspects of intellectual property Rights (TRIPS) agreement; and 4) achieving equity in global health funding and education resources.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-02-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10906336/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140023036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Framework for Evaluating Local Adaptive Capacity to Health Impacts of Climate Change: Use of Kenya’s County-Level Integrated Development Plans 气候变化对健康影响的地方适应能力评估框架:利用肯尼亚县级综合发展计划
IF 2.9 4区 医学
Annals of Global Health Pub Date : 2024-02-14 DOI: 10.5334/aogh.4266
Megan Kowalcyk, S. Dorevitch
{"title":"A Framework for Evaluating Local Adaptive Capacity to Health Impacts of Climate Change: Use of Kenya’s County-Level Integrated Development Plans","authors":"Megan Kowalcyk, S. Dorevitch","doi":"10.5334/aogh.4266","DOIUrl":"https://doi.org/10.5334/aogh.4266","url":null,"abstract":"Background: Health National Adaptation Plans were developed to increase the capacity of low- and middle-income countries (LMICs) to adapt to the impacts of climate change on the health sector. Climate and its health impacts vary locally, yet frameworks for evaluating the adaptive capacity of health systems on the subnational scale are lacking. In Kenya, counties prepare county integrated development plans (CIDPs), which contain information that might support evaluations of the extent to which counties are planning climate change adaptation for health. Objectives: To develop and apply a framework for evaluating CIDPs to assess the extent to which Kenya’s counties are addressing the health sector’s adaptive capacity to climate change. Methods: CIDPs were analyzed based on the extent to which they addressed climate change in their description of county health status, whether health is noted in their descriptions of climate change, and whether they mention plans for developing climate and health programs. Based on these and other data points, composite climate and health adaptation (CHA) scores were calculated. Associations between CHA scores and poverty rates were analyzed. Findings: CHA scores varied widely and were not associated with county-level poverty. Nearly all CIDPs noted climate change, approximately half mentioned health in the context of climate change and only 16 (34%) noted one or more specific climate-sensitive health conditions. Twelve (25%) had plans for a sub-program in both adaptive capacity and environmental health. Among the 24 counties with plans to develop climate-related programs in health programs, all specified capacity building, and 20% specified integrating health into disaster risk reduction. Conclusion: Analyses of county planning documents provide insights into the extent to which the impacts of climate change on health are being addressed at the subnational level in Kenya. This approach may support governments elsewhere in evaluating climate change adaptation for health by subnational governments.","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":null,"pages":null},"PeriodicalIF":2.9,"publicationDate":"2024-02-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139838747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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