Annals of Global HealthPub Date : 2026-08-19eCollection Date: 2026-01-01DOI: 10.5334/aogh.5223
Celia Wolfman, UnJa Hayes, Roger I Glass, Peter H Kilmarx, Rachel Sturke
{"title":"Two Decades of Fogarty Training: Nurturing Global Health Scientists.","authors":"Celia Wolfman, UnJa Hayes, Roger I Glass, Peter H Kilmarx, Rachel Sturke","doi":"10.5334/aogh.5223","DOIUrl":"10.5334/aogh.5223","url":null,"abstract":"<p><p><i>Background:</i> Scientific advances in global health rely on interdisciplinary researchers collaborating across cultures and orders to tackle complex health challenges. Sustained investment in the next generation of researchers is essential to maintaining this critical global health science capacity. This original article examines factors associated with the Fogarty International Center's (FIC) research training programs that produce independent global health researchers. <i>Objectives:</i> To examine factors within the FIC's research training programs that are associated with the successful production of independent global health scientists and to evaluate the long-term impact of the programs on alumni careers. <i>Methods:</i> This analysis synthesizes evidence from two cross-sectional surveys of FIC program trainees spanning the years 2003-2021. The surveys collected data from 717 and 690 alumni (with a 58% and 56% response rate, respectively). The analysis incorporates training experiences, career trajectories, and factors that influence professional independence, productivity, and research commitment. <i>Findings:</i> The analysis shows the program has successfully supported and expanded the global health research workforce. Sixty-two percent (62%) of alumni have careers in academia and 59% are actively working in research. Respondents consistently noted the importance of mentoring, protected research time, and robust professional networks contributing to a successful fellowship experience. The program has effectively stimulated interest, enlisted new partners, and addressed workforce development needs in global health research among early-career professionals in public health and medicine. <i>Conclusions:</i> FIC's research training programs are a successful model for developing the global health research workforce. Sustained training that emphasizes strong mentorship, dedicated research time, and collaborative partnerships is critical for fostering professional development and maximizing the long-term impact on global health equity.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"81"},"PeriodicalIF":5.1,"publicationDate":"2026-08-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13496228/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799958","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Global HealthPub Date : 2026-08-18eCollection Date: 2026-01-01DOI: 10.5334/aogh.5165
Than-Tun Sein, Win Han Oo, Thin Mar Win, Ko Ko Zaw, Poe Poe Aung, Kyu Kyu Than, Robert Wachbroit, Phone Myint Win, Henry Silverman
{"title":"Building Health Equity Research Capacity in Myanmar Through a Virtual, Mentor-Based Training Program.","authors":"Than-Tun Sein, Win Han Oo, Thin Mar Win, Ko Ko Zaw, Poe Poe Aung, Kyu Kyu Than, Robert Wachbroit, Phone Myint Win, Henry Silverman","doi":"10.5334/aogh.5165","DOIUrl":"10.5334/aogh.5165","url":null,"abstract":"<p><p><i>Background:</i> In Myanmar, the COVID-19 pandemic and political unrest beginning in 2021 exacerbated longstanding health inequities and disrupted health services, universities, and research governance, rendering in-person research training infeasible when locally led health equity research was urgently needed. <i>Objectives:</i> To describe the design, implementation, and evaluation of a fully virtual, mentor-based health equity research training program in Myanmar. <i>Methods:</i> Supported by the Fogarty International Center/NIH, a one-year virtual training program integrated weekly virtual Zoom sessions, asynchronous learning through a learning management system, and structured faculty mentorship. Program evaluation employed a mixed-methods approach that included participant and faculty surveys, objective assessment of analytic projects using a standardized scoring rubric, and analysis of the program interpreted through the RE-AIM framework. <i>Findings:</i> Of the initial 14 participants from civil society organizations and international nongovernmental organizations, 12 completed the program. Participants developed analytic projects using secondary datasets available through their organizations. These projects addressed health equity priorities, maternal health, COVID-19 impacts on informal workers, and disparities among displaced populations. Five subsequently produced full manuscripts. Objective evaluation demonstrated consistently high manuscript quality (mean rubric score 86.4/100, SD 2.8). Quantitative evaluations indicated high satisfaction with the program structure, learning resources, faculty engagement, and virtual mentoring. Qualitative findings highlighted the accessibility of the virtual format, gains in health equity knowledge and research skills, and the importance of sustained mentorship, while identifying the need for additional quantitative methods support and more individualized feedback. <i>Conclusions:</i> A fully virtual, mentor-based training program can sustain health equity research capacity in fragile and conflict-affected settings when in-person training is not feasible. Beyond maintaining educational continuity, the program supported the development of high-quality analytic projects and scholarly manuscripts, demonstrating that context-sensitive virtual training can strengthen locally led research capacity and institutional resilience during prolonged humanitarian and political disruption.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"80"},"PeriodicalIF":5.1,"publicationDate":"2026-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13496231/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148800005","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Global HealthPub Date : 2026-08-17eCollection Date: 2026-01-01DOI: 10.5334/aogh.5338
Morie Vandi, John M Koroma, Mustapha S Kabba
{"title":"Repositioning Primary Health Care in Sierra Leone: From Geographic Access to Effective Coverage.","authors":"Morie Vandi, John M Koroma, Mustapha S Kabba","doi":"10.5334/aogh.5338","DOIUrl":"10.5334/aogh.5338","url":null,"abstract":"<p><p>Primary health care (PHC) is central to Sierra Leone's efforts to achieve universal health coverage. Despite substantial expansion of the peripheral health unit network, improvements in geographic access have not consistently translated into better health outcomes. This viewpoint argues that Sierra Leone must shift its focus from physical access to effective coverage, defined as the proportion of people who receive care of sufficient quality to produce meaningful health gains. Key challenges include persistent out-of-pocket expenditure, shortages of salaried health workers, weak service readiness, fragmented vertical programmes, limited digital infrastructure, and variable implementation capacity. Addressing these constraints will require reforms in financing, workforce formalisation, quality improvement, programme integration, and accountability. Strengthening these areas will be essential for ensuring that PHC delivers equitable and measurable health gains for all Sierra Leoneans.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"79"},"PeriodicalIF":5.1,"publicationDate":"2026-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13496230/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148799978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Global HealthPub Date : 2026-08-06eCollection Date: 2026-01-01DOI: 10.5334/aogh.5266
Stephen Alajajian, Charis Eirené Gudiel de León, Lilian Carolina Ajú Batz, Peter Rohloff
{"title":"Breastfeeding and Complementary Feeding Practices of Children with Stunting in Guatemala.","authors":"Stephen Alajajian, Charis Eirené Gudiel de León, Lilian Carolina Ajú Batz, Peter Rohloff","doi":"10.5334/aogh.5266","DOIUrl":"10.5334/aogh.5266","url":null,"abstract":"<p><p><i>Background:</i> Stunting is a pervasive issue in low‑ and middle‑income countries, reflecting biological processes that adversely affect childhood cognitive development and increase the risk of chronic disease in adulthood. Nutritional intake is an important causative factor in stunting. Understanding the nutritional intake patterns of children with stunting can help inform nutrition program development. <i>Objective:</i> To characterize breastfeeding and dietary patterns from a clinical cohort of children with stunting in Guatemala and identify factors associated with linear growth. <i>Methods:</i> We included children with at least one diet record and one length/height‑for‑age z‑score below -2 from ages 0-5 years. We excluded children enrolled in complex care for severe non‑nutritional illness and records from prior to 6 months of age. We described adherence to World Health Organization infant and young child feeding indicators upon program enrollment. We longitudinally characterized breastfeeding and complementary feeding patterns of the cohort using generalized additive mixed modeling. We identified and quantified associations between various nutritional factors and linear growth using linear mixed effects models. <i>Results:</i> The final analytical dataset included 19,476 patient encounters from 2,352 children. Most children did not meet World Health Organization standards for dietary adequacy upon enrollment in the program. Dietary intakes were predominantly carbohydrate‑based. The factors most strongly associated with linear growth were food insecurity (negatively associated), portion size, and continued breastfeeding from 12 to 23 months. Adherence to the infant and young child feeding indicators was positively associated with linear growth. The intake of most food groups was also positively associated with linear growth. <i>Conclusions:</i> These findings suggest that the nutritional focus of interventions should be on adequate dietary diversity, earlier introduction and higher frequency of the less frequently consumed food groups, age‑appropriate portion sizes, and breastfeeding through 2 years of age. Public policy measures to address food insecurity are also necessary.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"78"},"PeriodicalIF":5.1,"publicationDate":"2026-08-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13450269/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148698227","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Climate Change as a Health Security Threat in Pakistan: Preparing Health Systems for Extreme Events.","authors":"Tayyab Mansoor Akhtar, Hashaam Akhtar, Babar Tasneem Shaikh, Zahra Hassan","doi":"10.5334/aogh.5294","DOIUrl":"10.5334/aogh.5294","url":null,"abstract":"<p><p>Pakistan is confronting the climate crisis as an immediate and systemic threat to national health security rather than an environmental concern. Recurrent floods between 2022 and 2025 affected more than 26 million people, damaged health infrastructure, disrupted essential services, and placed the country at the top of the Germanwatch Climate Risk Index. These shocks have intensified pre-existing health system fragilities by driving surges in malaria, waterborne infections, malnutrition, antimicrobial resistance, and forced displacement, while constraining routine service delivery. Climate-related migration to peri-urban informal settlements has created new epidemiological vulnerabilities characterized by overcrowding, poor sanitation, and outbreaks such as extensively drug-resistant typhoid. Simultaneously, crop losses and food system disruption have worsened child undernutrition in districts already exceeding emergency thresholds, with women and children disproportionately affected because of structural barriers to maternal, neonatal, and immunization services. Climate variability is also increasing the risk of zoonotic spillover and undermining progress toward Universal Health Coverage. We argue that climate change functions as a threat multiplier for Pakistan's health security and must be systematically integrated into health policy and planning. Key priorities include climate-resilient health infrastructure, strengthened integrated surveillance using digital and geospatial tools, prevention-oriented primary care, and operationalization of a One Health framework. Effective intersectoral governance, provincial implementation, and sustained collaboration with international partners, including the World Health Organization, are essential for building a resilient health system capable of maintaining continuity of care during increasingly frequent climate shocks.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"76"},"PeriodicalIF":5.1,"publicationDate":"2026-07-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13426462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Global HealthPub Date : 2026-07-28eCollection Date: 2026-01-01DOI: 10.5334/aogh.5195
Yannick Mulders, Scott Cann, Christopher Carpenter, Thomas C Chiles, Henoch Kabeya, Aoife Lyons, Saisha Shetty, Christopher Sonn, Christos Symeonides, Zahra Tahroudi, Kul Thapa, Philip J Landrigan, Sarah Dunlop
{"title":"PlasticHealthAware: Presenting the Latest Meta-Analytical Findings on Plastic Chemicals and Human Health.","authors":"Yannick Mulders, Scott Cann, Christopher Carpenter, Thomas C Chiles, Henoch Kabeya, Aoife Lyons, Saisha Shetty, Christopher Sonn, Christos Symeonides, Zahra Tahroudi, Kul Thapa, Philip J Landrigan, Sarah Dunlop","doi":"10.5334/aogh.5195","DOIUrl":"10.5334/aogh.5195","url":null,"abstract":"","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"76"},"PeriodicalIF":5.1,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13426463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654600","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Global HealthPub Date : 2026-07-27eCollection Date: 2026-01-01DOI: 10.5334/aogh.5185
Emmanuel Ndaba, Vukosi Baloyi
{"title":"Acute Kidney Injury After Cardiac Surgery in Low- and Middle-Income Countries.","authors":"Emmanuel Ndaba, Vukosi Baloyi","doi":"10.5334/aogh.5185","DOIUrl":"10.5334/aogh.5185","url":null,"abstract":"<p><p><i>Background:</i> Cardiac-surgery-associated acute kidney injury (CSA-AKI) is a frequent postoperative complication worldwide and is associated with increased mortality, prolonged intensive care unit stay, and substantial resource utilization. While reported incidence appears broadly similar across high-income countries (HICs) and low- and middle-income countries (LMICs), emerging evidence suggests marked disparities in severity at presentation and clinical outcomes. <i>Objectives:</i> To compare the epidemiology, severity, outcomes, and health-system determinants of CSA-AKI across HIC and LMIC settings, and to identify system-level contributors to excess mortality in resource-limited environments. <i>Methods:</i> We conducted a focused narrative review of contemporary observational studies reporting CSA-AKI incidence, severity, renal replacement therapy (RRT) utilization, and mortality following adult cardiac surgery. Literature was identified through targeted searches of PubMed/MEDLINE and hand-searching of reference lists. Priority was given to studies using standardized AKI definitions (RIFLE, AKIN, or KDIGO) and reporting clinically relevant perioperative outcomes. <i>Findings:</i> Across income settings, CSA-AKI incidence ranged from approximately 20% to 43%. However, LMIC cohorts consistently demonstrated more advanced AKI at diagnosis and substantially higher AKI-associated mortality, particularly among patients requiring RRT. In HICs, dialysis-requiring CSA-AKI was uncommon (~1%) but carried high mortality despite early detection and unrestricted access to renal support. In contrast, LMIC settings reported lower RRT utilization, delayed initiation, and mortality exceeding 40-55% in advanced AKI stages. <i>Conclusions:</i> CSA-AKI is a common global complication of cardiac surgery with disproportionately severe consequences in resource-limited settings. Excess mortality in LMICs appears largely driven by delayed detection and constrained rescue capacity rather than biological susceptibility alone. Strengthening perioperative surveillance and access to timely renal support may substantially reduce avoidable mortality.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"75"},"PeriodicalIF":5.1,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13426449/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654901","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Global HealthPub Date : 2026-07-27eCollection Date: 2026-01-01DOI: 10.5334/aogh.5156
Joseph Etah Oben
{"title":"Health-Climate Change-Migration Triad and Elderly Migrant Health in Africa.","authors":"Joseph Etah Oben","doi":"10.5334/aogh.5156","DOIUrl":"10.5334/aogh.5156","url":null,"abstract":"<p><p>Climate change is a contributing factor to the high burden of infectious and noncommunicable diseases in Africa, in particular a resource-poor setting already faced with worsening humanitarian and socio-economic crises, as well as a rising incidence and prevalence of noncommunicable and chronic diseases. Thus, examining studies on the triad, climate change-migration-health, would provide more direction on how climate change mitigation can be incorporated into health system planning in Africa. This paper seeks to review studies on the climate change-migration-health triad with a particular focus on those that address elderly health outcomes in relation to the triad and provide guidelines on how governments can enhance their health systems and mitigate climate change to enable the elderly and elderly migrants to cope and age healthily. The author conducted a review of research articles, reviews, and documents using online databases, including Google Scholar, Google, and Web of Science. The following keywords were combined with the Boolean operators AND and OR to conduct the search: ageing population, environmental changes, climate change, gerontology, and the elderly. Limiters were: language: papers published in English on the themes; and period: papers and documents from 1990 to 2025. Documents, papers, and articles were from both regional (African region) and international sources. The author's search lasted 3 weeks and yielded 44 articles, of which 18 were selected for thematic analysis. Thematic analysis of articles revealed that climate change impacts on the elderly are severe, with the elderly migrants presenting a greater vulnerability; impacts of climate change on African health systems are projected to be severe due to weak health systems. This paper underscores the need for African health systems to integrate data-driven climate change mitigation strategies into health systems and improve community engagement and international collaboration to tackle climate change and health system challenges.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"74"},"PeriodicalIF":5.1,"publicationDate":"2026-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13426448/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148654308","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Climate-Driven Shifts in Crimean-Congo Hemorrhagic Fever Epidemiology in Kazakhstan.","authors":"Fariza Khozhamkul, Turliyev Zangar, Rabiga Khozhamkul, Aizhan Esmagambetova, Manar Smagul, Tuleuov Akan","doi":"10.5334/aogh.5327","DOIUrl":"10.5334/aogh.5327","url":null,"abstract":"<p><p><i>Background:</i> Crimean-Congo Hemorrhagic Fever (CCHF) is a severe zoonotic viral disease that poses significant public health challenges in Kazakhstan, particularly in the southern regions where it has been endemic for decades. The natural focus of CCHF in this region has expanded significantly, a trend likely exacerbated by climate change. <i>Objective(s):</i> To analyze the outbreak trends of CCHF in four regions of Kazakhstan and assess the potential impact of climate variables on disease incidence. <i>Methods:</i> This ecological study examined CCHF morbidity and mortality data from 2014 to 2023 in the Zhambyl, Turkistan, and Kyzylorda regions, and Shymkent City. Data were sourced from the national central data repository. Meteorological data (temperature and precipitation) were obtained from the Climatic Research Unit TS dataset. Regression analysis was performed to test the dependence of CCHF incidence on climate variables. <i>Findings:</i> A total of 214 CCHF cases were reported in the study regions over the decade, with an overall case fatality rate of 21.5%. In the Kyzylorda region, a strong positive correlation was observed between climate indicators and annual case numbers (R-squared = 0.8969, <i>P</i> = 0.011). However, in Zhambyl and Turkistan regions, no significant associations emerged between climate variables and incidence during this period. Both average and extreme temperatures showed a gradual increase across all regions over the 10-year period. <i>Conclusions:</i> While the direct correlation between climate variables and CCHF incidence varied by region, long-term temperature trends likely influence tick ecology. The findings highlight the complexity of evaluating CCHF dynamics solely through a climate lens and underscore the need for a One Health approach, improved surveillance, and cross-border cooperation to mitigate this growing public health threat.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"73"},"PeriodicalIF":5.1,"publicationDate":"2026-07-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13398575/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148585793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Annals of Global HealthPub Date : 2026-07-23eCollection Date: 2026-01-01DOI: 10.5334/aogh.5194
Sofia Leonardo, Federico Antillón, Mulugeta Ayalew, Maria de Los Angeles Carrillo, Darrell Manuel Espinoza, Ram Hari Chapagain, Erika Damasco-Avila, Tigist Dawit, Thais Amelia Domínguez, Juna Dhungana, Samantha Ysabelle Ecleo, Sima Ferman, Ligia Fu, Pascale Gassant, Daniel Hailu, Tadele Hailu, Anna Henry, Joyce Kambugu, Francine Kouya, Esther Majaliwa, Barbara Muliro, Mariana Murra, Emanuel Nkya, Irene Nzamu, Wilson Oliveira, Marciel Pedro, Sudhir Sapkota, Trish Scanlan, Joseph Mary Semujju, Carolina Fernandes de Macedo Soares, Tombuh Happiness Sui, Karina Viani, Michelle Walters, Ephrata Yemane, Tsigereda Yitbarek, Stephany Zelaya Sagastizado, Elena J Ladas
{"title":"Evaluating a Global Clinical Nutrition Program for Pediatric Oncology in Resource-Limited Settings.","authors":"Sofia Leonardo, Federico Antillón, Mulugeta Ayalew, Maria de Los Angeles Carrillo, Darrell Manuel Espinoza, Ram Hari Chapagain, Erika Damasco-Avila, Tigist Dawit, Thais Amelia Domínguez, Juna Dhungana, Samantha Ysabelle Ecleo, Sima Ferman, Ligia Fu, Pascale Gassant, Daniel Hailu, Tadele Hailu, Anna Henry, Joyce Kambugu, Francine Kouya, Esther Majaliwa, Barbara Muliro, Mariana Murra, Emanuel Nkya, Irene Nzamu, Wilson Oliveira, Marciel Pedro, Sudhir Sapkota, Trish Scanlan, Joseph Mary Semujju, Carolina Fernandes de Macedo Soares, Tombuh Happiness Sui, Karina Viani, Michelle Walters, Ephrata Yemane, Tsigereda Yitbarek, Stephany Zelaya Sagastizado, Elena J Ladas","doi":"10.5334/aogh.5194","DOIUrl":"10.5334/aogh.5194","url":null,"abstract":"<p><p><i>Background:</i> Children with cancer in low- and middle-income countries (LMICs) experience disproportionately high mortality. Nutritional care improves treatment tolerance and survival, yet access to trained nutrition professionals remains limited. The International Initiative for Pediatrics and Nutrition (IIPAN) was established to strengthen hospital-based clinical nutrition services through capacity-building, education, and mentorship. <i>Objectives:</i> To evaluate the IIPAN global clinical nutrition capacity-building program across hospitals in LMICs. <i>Methods:</i> A monitoring and evaluation framework was implemented across 16 hospitals in 11 countries (February 2024-June 2025). Monthly indicators captured patient characteristics, nutritional status, delivery of nutrition interventions, and dietary diversity. Nutritional status was classified using body mass index (BMI)-for-age, mid-upper arm circumference (MUAC), and height-for-age z-scores based on World Health Organization standards. <i>Findings:</i> Across all sites, 29,295 clinical visits were reported. Most consultations occurred in inpatient settings (79.9%) and were follow-up assessments (85.1%). Among patients, 52.5% had solid tumors and 39.6% had hematologic malignancies. Based on BMI-for-age, 10.3% were classified with severe acute malnutrition (SAM) and 13.5% with moderate acute malnutrition (MAM). Height-for-age analysis indicated that 27.2% were stunted. Nearly all hospitalized patients (95.8%) received a nutrition assessment within 24 hours of admission, and 96.0% received individualized or group nutrition education. Therapeutic foods or formulas were provided in 42.8% of consultations, while advanced nutrition therapy was administered in 3.5%. The prevalence of acute malnutrition decreased significantly between initial and follow-up assessments (38.9% to 25.2%; <i>P</i> < 0.001). In sites with food kitchens, provision of therapeutic nutrition was substantially higher than program-wide for both children consuming ≤50% of estimated needs (87.4% vs 55%) and for children with SAM (99.1% vs 86%). <i>Conclusions:</i> The IIPAN model demonstrates that integrated, hospital-based nutrition care led by trained nutritionists can reduce acute malnutrition and improve access to essential nutrition services in LMICs.</p>","PeriodicalId":48857,"journal":{"name":"Annals of Global Health","volume":"92 1","pages":"72"},"PeriodicalIF":5.1,"publicationDate":"2026-07-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13426452/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148653815","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}