Archivos Espanoles De Urologia最新文献

{"title":"Prevalence of Lower Urinary Tract Symptoms and Contributing Factors among Medical Students.","authors":"Muharrem Baturu, Omer Bayrak, Alper Aytekin, Ozlem Basgut, Ilker Seckiner","doi":"10.56434/j.arch.esp.urol.20257802.18","DOIUrl":"10.56434/j.arch.esp.urol.20257802.18","url":null,"abstract":"<p><strong>Background: </strong>Lower urinary tract symptoms are observed in individuals with pathologies affecting the lower urinary system. This survey aimed to evaluate the prevalence of lower urinary tract symptoms and the contributing factors amongst medical students, a young population undergoing a stressful educational process.</p><p><strong>Methods: </strong>A 43-question survey was prepared for the first to sixth year medical students, incorporating the constipation scoring system to evaluate constipation, the generalized anxiety disorder 7-item scale to assess anxiety levels, and the core lower urinary tract symptom score to explore the lower urinary tract symptoms. The survey collected data on dietary habits, smoking status, consumption of alcoholic and caffeinated drinks, living conditions, age, gender, body mass index and educational level of the participants.</p><p><strong>Results: </strong>The sample included 222 participants, with a median age of 22 years. The participants consisted of male (46.4%) and female (53.6%) students. The prevalence of lower urinary tract symptoms was 83.78%. Amongst storage symptoms, urgency was the most frequent, affecting 59.0% of participants. Additionally, 58.10% of individuals experienced at least one voiding symptom, with the feeling of incomplete bladder emptying being the most common. In multivariate analyses, constipation (<i>p</i> < 0.001), gender (<i>p</i> = 0.016), anxiety (<i>p</i> = 0.027) and smoking (<i>p</i> = 0.014) were risk factors for storage symptoms, and increased body mass index (<i>p</i> = 0.048) and constipation (<i>p</i> < 0.001) were risk factors for voiding symptoms.</p><p><strong>Conclusions: </strong>This study highlights the high prevalence of lower urinary tract symptoms amongst medical students and identifies various contributing factors. The findings underscore the need for awareness and interventions to address lower urinary tract symptoms in this population, particularly considering its effect on quality of life.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"128-135"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Implementation of Watson's Caring Model in Nursing to Improve Self-Esteem, Depression, and Resilience in Patients after Radical Prostatectomy for Prostate Cancer: A Retrospective Study.","authors":"Jun Yan, Chen Liang, Xiaohui Chen, Lin Sun","doi":"10.56434/j.arch.esp.urol.20257802.25","DOIUrl":"10.56434/j.arch.esp.urol.20257802.25","url":null,"abstract":"<p><strong>Background: </strong>This study aimed to investigate the impact of Watson's Caring Model in Nursing (WCMN) on self-esteem, depression, resilience, quality of life, and patient satisfaction as well as determine potential outcome differences between patients receiving this personalised nursing care model and those provided with standard nursing care.</p><p><strong>Methods: </strong>This retrospective study included 113 patients who underwent radical prostatectomy at our hospital from January 2023 to June 2023. According to the type of care received, the patients were categorised into a traditional nursing group (n = 67) and a WCMN group (n = 46). Data collected from the patients included demographic information and the measurements of self-esteem (Self-Esteem Scale), depression (Hamilton Depression Rating Scale), resilience (Connor-Davidson Resilience Scale), and quality of life (Short Form 12) at baseline and 1 week post-surgery.</p><p><strong>Results: </strong>The WCMN group showed a significant increase in follow-up self-esteem scores compared to those in the traditional nursing group (t = 2.547, <i>p</i> = 0.012). Additionally, the WCMN group exhibited significantly lower follow-up depression scores (t = 2.035, <i>p</i> = 0.044) and higher resilience scores (t = 2.046, <i>p</i> = 0.044) and quality of life scores (t = 2.100, <i>p</i> = 0.038) than the traditional nursing group. Lastly, patient satisfaction scores, including overall satisfaction, nursing care satisfaction, information satisfaction, emotional support satisfaction, and involvement satisfaction scores, were significantly higher in the WCMN group than in the traditional nursing group (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>WCMN has a beneficial effect on self-esteem, depression, resilience, quality of life, and patient satisfaction in patients who undergo radical prostatectomy for prostate cancer.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"176-182"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biochemical Recurrence Following Radical Prostatectomy for Prostate Cancer with Positive Surgical Margins.","authors":"Rongrong Meng, Xuefen Wang, Zhengzheng Shi","doi":"10.56434/j.arch.esp.urol.20257802.24","DOIUrl":"10.56434/j.arch.esp.urol.20257802.24","url":null,"abstract":"<p><strong>Objective: </strong>Approximately one-third of individuals diagnosed with prostate cancer (PCa) experience biochemical recurrence (BCR) following their initial curative therapy. BCR significantly increases the risk of distant metastases and is associated with higher mortality rates, particularly in patients with poor prognostic indicators. This study aims to investigate the strong correlation between positive surgical margins (PSMs) and BCR after radical prostatectomy, offering foundational insights and guidance for predicting patient survival and optimising postoperative intervention strategies.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on the clinical data of 498 patients who underwent laparoscopic radical prostatectomy between January 2015 and January 2021 at Ningbo Yinzhou No.2 Hospital. Pathological specimens and medical records were reviewed. Of these, 127 patients with PSMs and 279 patients with negative surgical margins (NSMs) were included in the statistical analysis. The analysis incorporated clinical and pathological parameters, including primary tumour characteristics, PSMs, pathological tumour staging, surgical margin status, Gleason grade group, and other relevant factors, with BCR-free survival as the primary endpoint.</p><p><strong>Results: </strong>During the follow-up period of this study, 129 cases of BCR were identified among the 406 patients. Of these, 34 cases occurred in patients with PSMs, accounting for approximately 26.8% (34/127), and 95 cases occurred in patients with NSMs, accounting for approximately 34.1% (95/279). The difference in recurrence between the two groups was statistically significant (<i>p</i> < 0.001). The median time to BCR was 19.2 months for patients with PSMs, compared to 28.2 months for patients with NSMs, with this difference also reaching statistical significance (<i>p</i> < 0.001). The Gleason grading group in patients with PSMs was a stronger predictor of recurrence than the primary tumour characteristics.</p><p><strong>Conclusions: </strong>The presence of PSMs is a significant independent predictor of BCR in patients undergoing radical prostatectomy for PCa. Early detection and timely intervention for patients with PSMs are crucial for improving postoperative outcomes.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"170-175"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796634","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluating the Efficacy and Safety of Durvalumab Plus Radiotherapy in Second-Line Treatment for Advanced Bladder Cancer.","authors":"Dongyang Yu, Dawei Liu, Yang Liu","doi":"10.56434/j.arch.esp.urol.20257802.33","DOIUrl":"10.56434/j.arch.esp.urol.20257802.33","url":null,"abstract":"<p><strong>Background: </strong>Bladder cancer is a common malignancy that arises from the urothelium. Treatment options for advanced bladder cancer remain limited, particularly in patients who have progressed after first-line therapy. Immunotherapy with programmed death-ligand 1 (PD-L1) inhibitors, such as durvalumab, has shown promise in improving outcomes in these patients. Radiotherapy (RT) is another modality that can be integrated to enhance local tumour control. This study explored the efficacy and safety of combining durvalumab with RT as a second-line treatment for patients with advanced bladder cancer, aiming to provide insights into its potential therapeutic benefits. Bladder cancer is a type of malignant tumour that arises from the epithelial lining of the bladder and commonly manifests as haematuria and frequent urination.</p><p><strong>Methods: </strong>A total of 58 patients who were diagnosed with advanced bladder cancer and treated at our hospital between January 2020 and June 2022 were retrospectively analysed. Patients were divided into two groups: A control group (n = 33) receiving durvalumab monotherapy and an observation group (n = 25) receiving durvalumab combined with RT. The remission rates, two-year survival rates, median survival times, serum tumour marker levels and adverse events of the two groups were compared.</p><p><strong>Results: </strong>Before treatment, the differences in the serum tumour marker levels between the two groups (<i>p</i> > 0.05) were not significant. Compared with the control group, the observation group presented significantly lower serum tumour marker levels (<i>p</i> < 0.05). Furthermore, compared with the control group, the observation group had a higher overall clinical objective response rate (96.00% vs. 75.76%) and a better two-year survival rate (40.00% vs. 15.15%). Additionally, progression-free survival (PFS) was longer in the observation group (18 months vs. 16 months, <i>p</i> = 0.001).</p><p><strong>Conclusions: </strong>Durvalumab combined with RT as a second-line treatment for advanced bladder cancer effectively reduces the expression of tumour markers and improves two-year survival and PFS, offering valuable clinical insights.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"248-254"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796750","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of the Combination of the Family-Centred Care Model and Video Education on the Postoperative Recovery of Paediatric Urological Surgery Patients.","authors":"Jiayu Tan, Yubo Kang, Fengqiu Gong, Zheyan Huang, Yiguo Liufu, Shuaihui Zeng, Xiuhong Li","doi":"10.56434/j.arch.esp.urol.20257802.32","DOIUrl":"10.56434/j.arch.esp.urol.20257802.32","url":null,"abstract":"<p><strong>Background/purpose: </strong>Addressing perioperative anxiety, pain and restlessness and promoting family involvement through the family-centred care (FCC) model and video education may lead to improved postoperative outcomes. This study aimed to evaluate the effect of combining the FCC model with video education on the postoperative recovery of paediatric patients who underwent urological surgery.</p><p><strong>Methods: </strong>This prospective randomised controlled study enrolled 200 paediatric patients who were undergoing general anaesthesia and recovery in the post-anaesthesia care unit at The First Affiliated Hospital of Sun Yat-sen University from January to April 2024. They were randomly assigned to Group A (routine care), Group B (routine care + video education), Group C (routine care + FCC model) and Group D (routine care + video education + FCC model), with 50 cases in each group. Various indicators, including recovery trajectory, agitation and pain scores, psychological states and treatment compliance, were assessed and compared amongst the groups.</p><p><strong>Results: </strong>In the analysis of recovery trajectories, no significant differences were found amongst the groups in terms of time to resume breathing and extubation duration (<i>p</i> > 0.05). However, a notable distinction was observed in the recovery time of anaesthesia across the groups (<i>p</i> < 0.001). Compared with Groups B and C, Group D exhibited significant improvement in agitation and pain scores (<i>p</i> < 0.05). In addition, Group D had significantly lower anxiety level and higher treatment compliance than Groups B and C (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>The combined approach of the FCC model and video education may improve postoperative recovery outcomes in paediatric patients who underwent urological surgery. Hence, this approach is worth promoting and applying in clinical practice.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"240-247"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796711","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of Traditional Chinese Medicine Emotional Care on Patients with Urinary Incontinence after Transurethral Resection of the Prostate.","authors":"Yuan Zhang, Ling Zhang","doi":"10.56434/j.arch.esp.urol.20257802.29","DOIUrl":"10.56434/j.arch.esp.urol.20257802.29","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to explore the effects of traditional Chinese medicine (TCM) emotional care on improving the urinary incontinence symptoms and quality of life of patients after transurethral resection of the prostate (TURP).</p><p><strong>Methods: </strong>This retrospective cohort study included urinary incontinence patients who underwent TURP at our hospital from June 2021 to August 2023. The patients were divided into an observation group (receiving TCM emotional care) and a control group (receiving conventional care). Urinary incontinence symptoms, quality of life and psychological status were assessed using the International Consultation on Incontinence Questionnaire-Short Form (ICIQ-SF), the Incontinence Quality of Life Questionnaire (I-QOL), the Hamilton Depression Scale (HAMD) and the Hamilton Anxiety Scale (HAMA). Differences between the two groups were analysed using <i>t</i>-tests and repeated measures Analysis of Variance (ANOVA).</p><p><strong>Results: </strong>A total of 119 patients with post-TURP urinary incontinence were included in this study. In the observation group, the ICIQ-SF score decreased significantly (<i>p</i> < 0.001), whilst the control group also demonstrated improvement (<i>p</i> < 0.001). The I-QOL score in the observation group increased significantly (<i>p</i> < 0.001) compared with the control group (<i>p</i> < 0.001). For psychological health, the HAMD score improved in the observation group (<i>p</i> = 0.012), whilst the control group showed less improvement (<i>p</i> = 0.012). The HAMA score decreased significantly in the observation group (<i>p</i> = 0.029) compared with in the control group (<i>p</i> = 0.029).</p><p><strong>Conclusions: </strong>TCM emotional care significantly improves outcomes in patients with post-TURP urinary incontinence. It effectively reduces the severity of urinary incontinence, enhances quality of life and alleviates depressive and anxious symptoms.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"215-223"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Letter to the Editor Re: Research Progress and Efficacy Evaluation of Nivolumab in the Treatment of Metastatic Renal Cancer.","authors":"Lihua Liu, Shenfang Liu, Fang Zhao, Xinyu Jiang, Xing Dong","doi":"10.56434/j.arch.esp.urol.20257802.35","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257802.35","url":null,"abstract":"","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"263-264"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796790","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Efficacy of Ultrasound Combined with Computed Tomography Image Fusion Technology to Guide Percutaneous Nephrolithotomy for Treating Complex Renal Calculi.","authors":"Jinglei Wang, Fangwei You, Wentao Deng, Junfang Yang","doi":"10.56434/j.arch.esp.urol.20257802.30","DOIUrl":"10.56434/j.arch.esp.urol.20257802.30","url":null,"abstract":"<p><strong>Background: </strong>Percutaneous nephrolithotomy (PCNL) has become a standard surgical procedure for treating complex renal calculi. This study aims to explore the effect of ultrasound combined with computed tomography (CT) image fusion technology and to guide PCNL for treating complex renal calculi.</p><p><strong>Methods: </strong>A total of 130 patients with complex renal calculi who were admitted in our hospital from April 2021 to April 2023 were selected. After excluding four cases who did not meet the inclusion criteria, 126 cases were finally included. Based on the different treatment paths of PCNL, patients were divided into two groups. Among them, 60 patients who received CT guidance combined with ultrasound image fusion technology were selected as the observation group, and 66 patients who received routine guidance were included in the control group. The perioperative parameters and postoperative complications of patients in both groups were compared.</p><p><strong>Results: </strong>The observation group had shorter operation time and lower reoperation rate than the control group (<i>p</i> < 0.05). The first calculi clearance rate of the observation group was 88.33%, which was distinctly higher than that of the control group (71.21%, <i>p</i> < 0.05). However, no significant difference in length of hospital stay after surgery was found between the two groups (<i>p</i> > 0.05). The establishment time of a single channel and the average number of puncture channels were lower in the observation group than in the control group (<i>p</i> < 0.05). The success rate of establishing an initial channel in the observation group was 93.33%, which was significantly higher than that in the control group (80.30%, <i>p</i> < 0.05). The observation group had a significantly higher postoperative hemoglobin level than the control group (<i>p</i> < 0.05). No significant difference in serum creatinine level was found between the two groups (<i>p</i> > 0.05). The postoperative incidence of complications in the observation group was 6.67%, which was distinctly lower than that in control group (19.70%, <i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>The combination of CT and ultrasound image fusion technology for PCNL in the treatment of complex renal calculi demonstrates good clinical efficacy and high safety.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"224-229"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comprehensive Analysis of Roles of APOBEC3 Gene Family in Clear Cell Renal Cell Carcinoma.","authors":"Hanrong Zhang, Hui Luo, Li Zhao, Zhongying Yu, Shan Lin, Lianzheng Lin, Jinyu Li","doi":"10.56434/j.arch.esp.urol.20257802.26","DOIUrl":"10.56434/j.arch.esp.urol.20257802.26","url":null,"abstract":"<p><strong>Objectives: </strong>The current research focuses on a systematic analysis of the expression patterns of the apolipoprotein B editing complex 3 (<i>APOBEC3</i>) gene family in clear cell renal cell carcinoma (ccRCC) and their impact on disease progression, prognosis, and somatic gene mutations associated with ccRCC.</p><p><strong>Methods: </strong>A differential expression analysis was performed using the R \"limma\" package, while a survival analysis was performed using Kaplan-Meier and log-rank tests. A Gene Set Enrichment Analysis performed by the R \"clusterProfiler\" package compared the high- and low-expression groups. The 10 genes with the highest tumor mutation frequency in the patients with ccRCC were evaluated and presented using the R \"maftool\" package. The Tumor Immune Estimation Resource (TIMER) algorithm was utilized to predict the immune cell infiltration levels in ccRCC.</p><p><strong>Results: </strong>All members of the <i>APOBEC3</i> gene family members were found to be upregulated in ccRCC tumor tissues versus adjacent normal tissues. Higher expressions of <i>APOBEC3A</i>, <i>APOBEC3B</i>, <i>APOBEC3C</i>, <i>APOBEC3D</i>, <i>APOBEC3G</i>, and <i>APOBEC3H</i> were associated with a poorer prognosis for ccRCC. Conversely, higher <i>APOBEC3F</i> expression was associated with a more favorable ccRCC prognosis. Mutation frequencies of genes <i>VHL</i>, <i>PBRM1</i>, <i>TTN</i>, <i>SETD2</i>, and <i>BAP1</i> genes were higher in the high-expression group of various <i>APOBEC3</i> compared to the low-expression group. Multiple <i>APOBEC3</i> gene family (particularly <i>APOBEC3C</i>, <i>APOBEC3D</i>, <i>APOBEC3F</i>, <i>APOBEC3G</i>, and <i>APOBEC3H</i>) also correlated with immune cell infiltration in the ccRCC.</p><p><strong>Conclusions: </strong>These study findings suggest that <i>APOBEC3</i> genes are commonly overexpressed in ccRCC, and their expression levels are associated with poor prognosis in ccRCC, somatic gene mutations, cancer immunomodulation, and immune cell infiltration levels in the tumor microenvironment.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"183-193"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796636","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of the COVID-19 Pandemic on the Incidence and Composition of Urolithiasis in New Brunswick, Canada.","authors":"Iris Y Chen, Yu Chen","doi":"10.56434/j.arch.esp.urol.20257802.17","DOIUrl":"10.56434/j.arch.esp.urol.20257802.17","url":null,"abstract":"<p><strong>Introduction: </strong>The COVID-19 pandemic affected the presentation and management of many diseases. Lifestyle and dietary habit changes caused by social limitations and quarantine may alter the incidence of chronic diseases such as urolithiasis. This epidemiology study aimed to investigate the impact of the COVID-19 pandemic on the incidence of kidney stones in the Canadian province of New Brunswick.</p><p><strong>Methods: </strong>Reports of 3253 kidney stone analysis from 1 January 2021, to 31 December 2023, were retrospectively reviewed from the laboratory information system. All stone compositions were analysed by Fourier transforminfrared spectrometry technology. Incident rates were compared with 3838 urolithiasis reports from 1 October 2016, to 30 September 2019, stratified by different ages, sexes and the geographic regional health authority (RHA) zones.</p><p><strong>Results: </strong>The overall incidence of urolithiasis in New Brunswick significantly dropped from 148 (95% confidence interval (CI) 139-157) per 100,000 person-years in 2016-2019 to 115 (95% CI 110-120) per 100,000 person-years in the period of 2021-2023 (χ²: 94.167, <i>p</i> < 0.01, risk ratio: 0.78). The decrease occurred in both sexes, most age groups and the most densely populated RHA zones (Zones 1 and 2; <i>p</i> < 0.01). However, geographic differences on the impact of COVID-19 on prevalence were observed. Similar to that of the pre-COVID-19 period, calcium oxalate monohydrate remained as the predominant (61.27%) kidney stone type in 2021-2023. Struvite stone decreased from 2.19% to 0.86%.</p><p><strong>Conclusions: </strong>The incidence rate of urolithiasis in New Brunswick was significantly lower in the COVID-19 pandemic than in the pre-COVID-19 period. However, we found no significant change in kidney stone compositions.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 2","pages":"121-127"},"PeriodicalIF":0.6,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143796773","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}