Archivos Espanoles De Urologia最新文献

{"title":"Use of Inflammatory Markers in the Evaluation of Patients with Asymptomatic Microscopic Haematuria to Predict Malignancy.","authors":"Aydemir Asdemir, Sebahattin Albayrak","doi":"10.56434/j.arch.esp.urol.20257803.40","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.40","url":null,"abstract":"<p><strong>Objectives: </strong>This study assessed the use of inflammatory biomarkers in the prediction of malignancy in patients with asymptomatic microscopic haematuria.</p><p><strong>Methods: </strong>In this prospective study, patients between 18 and 65 years old with asymptomatic microscopic haematuria who presented at our urology clinic within 2 years were included. The patients had no urological complaints and had applied to other clinics for other reasons. Microscopic haematuria was detected, and the patients were referred to the urology clinic for investigation. The participants were included in a 6-month and 1-year follow-up protocol. All investigations and follow-ups were conducted by the same experienced doctor. The patients were divided into malignancy and non-malignant groups according to the definitive diagnosis after the necessary examinations (laboratory tests, medical imaging and pathological examination if necessary). Inflammatory parameters were compared statistically between the two groups. Receiver operating characteristic curve analysis was applied to inflammatory parameters to detect malignancy.</p><p><strong>Results: </strong>Asymptomatic microscopic haematuria was detected in 294 patients (242 males, 52 females). Malignancies in 98 of 294 patients were determined with various imaging and laboratory methods. The detected malignancies were confirmed with pathological examination. In addition, 196 of 294 age-matched and gender-matched patients without malignancy but with haematuria were used as the non-malignant group. Red blood cell distribution width, neutrophil-to-lymphocyte ratio, mean platelet volume, serum C-reactive protein and erythrocyte sedimentation rate of patients in the non-malignant group were lower than those with malignancy. Receiver operating characteristic curve analysis suggested that the optimum red blood cell distribution width cut-off point for patients with malignancy was 14.45, with a sensitivity and a specificity of 75% and 65%, respectively.</p><p><strong>Conclusions: </strong>Patients with high inflammatory biomarkers value, especially high red blood cell distribution width, should be evaluated in detail and carefully. Further large collective studies should be conducted to confirm the use of red blood cell distribution width in the prediction of malignancy in patients with asymptomatic microscopic haematuria. Patients with microscopic haematuria who have high erythrocyte sedimentation rate, neutrophil-to-lymphocyte ratio and C-reactive protein are at a high risk of malignancy and therefore should be followed up attentively.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"296-302"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004923","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A 20-Year Single-Centre Experience on Urogenital Tuberculosis.","authors":"Muhammet İrfan Dönmez, Rifat Burak Ergül, İsmail Selvi, Reşat Aydin, Gonca Erköse Genç, Dilek Şatana, Zayre Erturan, Meltem Uzun, Tayfun Oktar, Orhan Ziylan, İsmet Nane","doi":"10.56434/j.arch.esp.urol.20257803.36","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.36","url":null,"abstract":"<p><strong>Background: </strong>Urogenital tuberculosis (UGTb) is the second most common form of extrapulmonary Tb. We aimed to evaluate the clinical consequences in our 20-year experience of UGTb.</p><p><strong>Methods: </strong>We retrospectively reviewed the files of consecutive patients diagnosed with UGTb through microbiological methods between January 2001 and April 2021 in our centre. Clinical and demographic data of the patients were assessed. Surgical procedures during the disease course were also noted.</p><p><strong>Results: </strong>A total of 46 patients (26 males) having a median age of 48.5 (16-82) years were diagnosed with UGTb. The most frequent complaint at admission was lower urinary tract symptoms (LUTS), followed by nonspecific symptoms, macroscopic hematuria, flank pain, scrotal swelling, and infertility. A history of pulmonary Tb was present in 10 patients. The kidney was the most affected organ, followed by ureter, bladder, and testis/epididymis. Bladder involvement and admission with LUTS was significantly higher in elderly patients (≥60 years), whereas the rate of nonspecific symptoms was significantly higher in younger patients (≤40 years). Eleven patients required surgical interventions including nephrectomy (n = 5), nephroureterectomy (n = 2), orchiectomy (n = 1), epididymectomy (n = 1), distal ureterectomy + ureteroneocystostomy (n = 1), and epididymovasostomy (n = 1). Among the 32 patients with at least 12 months of follow-up (median 114 months, range: 12-180) four had ongoing LUTS, 5 had chronic kidney disease, one had end-stage renal disease, and one had azoospermia.</p><p><strong>Conclusions: </strong>UGTb affected the upper urinary tract with a fair chance of renal function deterioration in addition to LUTS and infertility. These conditions may impair the patient's long-term quality of life. Elderly patients were also more prone to bladder involvement, and approximately one-quarter of patients with UGTb required surgical intervention.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"265-271"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042432","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Early Palliative Care in Advanced or Metastatic Bladder Cancer: A Retrospective Study.","authors":"Xiaohong Xie, Yu Sang, Dan Shou","doi":"10.56434/j.arch.esp.urol.20257803.49","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.49","url":null,"abstract":"<p><strong>Aims: </strong>The quality of life for patients with advanced cancer declines, tending to deteriorate further as they approach the end of their lives. This retrospective study aimed to evaluate the potential benefits of incorporating early palliative care into routine care for patients with advanced or metastatic bladder cancer.</p><p><strong>Methods: </strong>A total of 97 patients with advanced or metastatic bladder cancer from January 2022 to May 2024 were included. Amongst them, 46 received routine treatment and early palliative care (observation group) and 51 received routine treatment only (control group). Assessments using Functional Assessment of Cancer Therapy-General (FACT-G), Brief Pain Inventory (BPI), Cancer Fatigue Scale (CFS), Hospital Anxiety and Depression Scale (HADS) and Family Satisfaction with Advanced Cancer Care-2 (FAMCARE-2) were conducted before and at 3 and 6 months after initiating early palliative care. Generalized estimating equation analysis was used for statistical analysis.</p><p><strong>Results: </strong>The indicators in the observation group showed improvement within 6 months after initiating early palliative care. Notably, the quality of life in the observation group significantly improved over this period (<i>p</i> = 0.013), whereas changes in pain scores were not statistically significant in either group (<i>p</i> > 0.05). The level of fatigue in the observation group decreased to its lowest point at 6 months (<i>p</i> = 0.001), whereas changes in fatigue levels in the control group were not significant (<i>p</i> > 0.05). Compared with the control group, the observation group experienced a significant reduction in depression and anxiety levels within 6 months (<i>p</i> < 0.001). The nursing satisfaction in the observation group increased over time, with statistical significance (<i>p</i> = 0.006). Notably, significant interaction effects were observed between time and group, particularly in fatigue and psychological distress.</p><p><strong>Conclusions: </strong>Early palliative care improves quality of life and reduces fatigue and psychological distress in patients within 6 months, without notable changes in pain scores. Integration of early palliative care into routine management is recommended to enhance patient well-being and satisfaction.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"371-379"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144044150","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Direct and Indirect Radionuclide Cystography: Can They Predict the Absence of Infectious Complications in Vesicoureteral Reflux?","authors":"Jorge Panach-Navarrete, Pablo Esteve-Juan, Lorena Valls-González, Héctor Rodríguez-Parra, Susana Ferrando-Monleón, Juan Marín-Serra, Rocío Gil-Viana, José María Martínez-Jabaloyas","doi":"10.56434/j.arch.esp.urol.20257803.37","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.37","url":null,"abstract":"<p><strong>Introduction: </strong>Radionuclide cystography is a commonly used examination technique for managing vesicoureteral reflux (VUR). Our aim was to compare direct radionuclide cystography (DRC) with indirect radionuclide cystography (IRC) and study the evolution of patients who tested negative for VUR using either test.</p><p><strong>Material and methods: </strong>A retrospective observational study was conducted by collecting all radionuclide cystography scans performed in our centre to detect VUR among paediatric patients over 5 years old. Subgroup analysis was also performed on DRC or IRC scans negative for VUR to study the occurrence of infectious complications in these patients during follow-up.</p><p><strong>Results: </strong>A total of 62 DRC and 46 IRC scans were collected from the patients with an average age of 65.4 ± 52.6 months at the time of the exam. Among the 62 DRC and 46 IRC cases, 38 and 34 tested negative for reflux, respectively. The IRC group showed a higher percentage of reinfection (62.5% vs. 37.5% of DRC, <i>p</i> = 0.16) and a greater number of visits to the emergency room due to infection (60% vs. 40% of DRC, <i>p</i> = 0.26) but a lower percentage of readmissions due to infection (33.3% vs. 66.7% of DRC, <i>p</i> = 0.47) than the DRC group. Among the remaining studied variables, only constipation was associated with an increased risk of admission due to infection (odds ratio (OR) = 29.62, <i>p</i> = 0.03) in these patients.</p><p><strong>Conclusions: </strong>Patients with IRC negative for VUR had a higher percentage of reinfections during follow-up than those with DRC negative for VUR, although the difference did not reach statistical significance. Furthermore, paediatric patients with a negative radionuclide cystography for VUR and who suffer from constipation have an increased risk of admission for infectious complications.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"272-279"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026342","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Role of Transrectal Ultrasound in Assessing Disease Progression and Indications for Invasive Treatment in Benign Prostatic Hyperplasia.","authors":"Jianshe Zhang, Jianhong Lan, Lijun Shen, Dan Zhu","doi":"10.56434/j.arch.esp.urol.20257803.47","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.47","url":null,"abstract":"<p><strong>Background: </strong>Transrectal ultrasound (TRUS) is a non-invasive and accurate imaging technique that plays a crucial role in evaluating the progression and pathological changes of benign prostatic hyperplasia (BPH). This study aimed to explore the relationship between TRUS parameters and BPH clinical progression, as well as the indications for invasive treatment, to provide more evidence for clinical decision making.</p><p><strong>Methods: </strong>This retrospective study included 648 BPH patients diagnosed and treated in our hospital between January 2021 and October 2023. All patients underwent TRUS, and parameters including prostate volume (PV), transition zone volume (TZV), transition zone index (TZI), and intravesical prostatic protrusion (IPP) were recorded. Patients were followed for 1 year, and data on clinical progression and invasive treatment were collected. Univariate and multivariate regression analyses were performed to evaluate the predictive value of TRUS parameters for clinical progression and treatment selection.</p><p><strong>Results: </strong>A total of 648 patients were included. During the 1-year follow-up, 75 patients experienced clinical progression, and 30 patients underwent invasive treatment. Univariate regression analysis revealed that TRUS parameters such as PV, TZV, and IPP were significantly associated with clinical progression and invasive treatment (<i>p</i> < 0.05). Multivariate regression analysis indicated that PV, TZV, and IPP were independent predictors of clinical progression, with an odds ratio (OR) of 1.114 (95% CI: 1.079-1.150) for PV, 1.062 (95% CI: 1.032-1.093) for TZV, and 1.427 (95% CI: 1.241-1.640) for IPP. Similarly, PV, TZV, and IPP were independent predictors for the occurrence of invasive treatment, with an OR of 1.064 (95% CI: 1.037-1.091) for PV, 1.030 (95% CI: 1.018-1.042) for TZV, and 1.135 (95% CI: 1.015-1.269) for IPP.</p><p><strong>Conclusions: </strong>TRUS parameters can effectively predict the clinical progression and need for invasive treatment in BPH patients. Clinicians can use these parameters to develop more accurate and personalised treatment plans for patients.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"352-357"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143993817","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Erectile Dysfunction in COPD: A Consequence or a Sign?","authors":"Nihat Türkmen, Cemil Kutsal, Müfide Arzu Özkarafakılı, Eminegül Yavuzsan","doi":"10.56434/j.arch.esp.urol.20257803.38","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.38","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is a disease that can be associated with other diseases and has systemic effects. The effects of the disease may lead to disruptions in the working mechanisms of other systems. In our study, we aimed to investigate the effects of COPD on sexual function and related psychological status in men.</p><p><strong>Materials and methods: </strong>The study included 60 male patients diagnosed with COPD in our hospital between March 2023 and May 2024. A control group consisting of 60 healthy individuals was also formed. Spirometry was performed in all patients. Assessment was performed using the COPD Assessment Test and the modified Medical Research Council scale, and three groups-Global Initiative for Chronic Obstructive Lung Disease (GOLD) A, GOLD B and GOLD E-were formed by combining the spirometric grading of COPD patients according to symptom level and exacerbation history. These three groups were evaluated by using the Beck Depression Inventory and International Index of Erectile Function (IIEF) tests, and the results were recorded. Blood samples were tested to measure asymmetric dimethylarginine levels. The results were statistically compared.</p><p><strong>Results: </strong>The mean values of forced expiratory volume in the first second of forced expiration (FEV₁) %, forced vital capacity (FVC) % and FEV₁/FVC % of the control group were statistically significantly higher than those of the patient group (<i>p</i> < 0.001). The Beck Depression scale score, moderate and severe depression rates were higher than those of the control group (<i>p</i> = 0.004). The IIEF and ejaculatory function scores were statistically significantly lower than those of the control group (<i>p</i> < 0.001 and <i>p</i> = 0.001, respectively).</p><p><strong>Conclusions: </strong>COPD is a disease that affects other systems aside from the respiratory system. The presence of COPD can have negative effects on sexual function.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"280-288"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055318","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of an Aerobic Exercise Programme on Bone Density in Middle-Aged and Elderly Patients with Prostate Cancer Undergoing Androgen Deprivation Therapy: A Retrospective Study.","authors":"Jing Lin, Laixiang Zhang, Xinxin Liu, Jing Meng, Zhao Ma","doi":"10.56434/j.arch.esp.urol.20257803.41","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.41","url":null,"abstract":"<p><strong>Background: </strong>Prostate cancer is a remarkable health concern in men, particularly in middle-aged and elderly men, with androgen deprivation therapy (ADT) being a common treatment approach for this malignancy. However, ADT is associated with adverse effects on bone health, including accelerated bone loss and decreased bone mineral density, leading to increased fracture risk. As a result, exploring interventions to mitigate ADT-induced bone loss is needed.</p><p><strong>Methods: </strong>This retrospective study analysed clinical data from middle-aged and elderly patients with prostate cancer undergoing ADT. Patients were divided into the routine treatment and aerobic exercise therapy groups on the basis of whether they participated in an aerobic exercise programme. Laboratory measurements included baseline and 4-month follow-up assessments of calcium, vitamin D, osteocalcin, cyclophosphamide (CTX) and bone density parameters analysed by using dual-energy X-ray absorptiometry.</p><p><strong>Results: </strong>This study involved 126 patients, including 62 patients receiving routine treatment and 64 patients participating in an aerobic exercise programme. At the 4-month follow-up, the aerobic exercise therapy group demonstrated significant improvements in calcium levels (8.94 ± 0.45 mg/dL vs. 8.68 ± 0.51 mg/dL, <i>p</i> = 0.003) and vitamin D levels (32.89 ± 6.17 ng/mL vs. 29.58 ± 5.68 ng/mL, <i>p</i> = 0.002) compared with the routine treatment group. No significant differences were observed in bone turnover markers at 4 months. At 4 months, the aerobic exercise therapy group showed significant increases in bone density in the lumbar spine, femoral neck, total hip, radius and whole body compared with the routine treatment group (<i>p</i> < 0.05). Correlation analysis revealed that the aerobic exercise programme had positive correlations with calcium level, vitamin D level, osteocalcin and bone density at various anatomical sites in the study population.</p><p><strong>Conclusions: </strong>This study provided compelling evidence of the beneficial effects of aerobic exercise programmes on bone density and related serum biomarkers in middle-aged and elderly patients with prostate cancer undergoing ADT.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"303-309"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic Efficacy of Prostate Biopsy by Transperineal Colour Ultrasound Plus Magnetic Resonance Imaging for Prostate Cancer and Analysis of Oxidative Stress Injury in Patients.","authors":"Wen Li, Yumei Fan, Caiqin Li","doi":"10.56434/j.arch.esp.urol.20257803.43","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.43","url":null,"abstract":"<p><strong>Objective: </strong>This study aims to evaluate the diagnostic effectiveness of prostate biopsies using transperineal colour ultrasound with magnetic resonance imaging (MRI) against transrectal colour ultrasound with MRI in treating prostate cancer (PCa) and oxidative stress injuries in patients.</p><p><strong>Methods: </strong>We conducted a backward-looking study on the medical records of 65 individuals suspected of having PCa who underwent prostate biopsies at our hospital from March 2022 to March 2024. In the transrectal prostate biopsy (TRPB) group, 32 patients underwent TRPB, whereas the transperineal prostate biopsy (TPPB) group utilised TPPB for 33 patients. Every patient received an MRI scan to verify the location of the puncture prior to it. The length of the puncture, the amount of biopsy cores collected and confirmed as positive and any negative responses postprocedure were thoroughly documented. The indices of oxidative stress injuries in both groups were assessed postpuncture, and the effectiveness levels of TPPB and TRPB in diagnosing PCa were compared.</p><p><strong>Results: </strong>No significant statistical variance existed between the two groups in the count of biopsy and positive biopsy cores (<i>p</i> > 0.05). However, compared with the duration of puncture in the TRPB group, that in the TPPB group was extended (<i>p</i> < 0.05). No significant variance in oxidative stress damage postpuncture existed amongst the groups (<i>p</i> > 0.05), and the TPPB group experienced fewer negative reactions than the TRPB group (<i>p</i> < 0.05). In terms of diagnostic effectiveness, TPPB's sensitivity, specificity and accuracy in detecting PCa stood at 84.62%, 85.00% and 84.85%, respectively, surpassing those of TRPB in Kappa value. Additionally, the overall prostate-specific antigen levels in the TPPB group's genuinely positive patients were notably less than those in the TRPB group (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>The combination of transperineal colour ultrasound and MRI is highly efficient in PCa diagnosis and is advised as the primary option in clinical settings.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"318-324"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144046759","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Pharmaceutical Services on Elderly Prostate Cancer: Drug-Related Problems, Disease Knowledge, Health-Related Quality of Life, and Satisfaction.","authors":"Xiaohua Zhang, Shaofeng Shao, Chongfeng Lin, Lin Hong","doi":"10.56434/j.arch.esp.urol.20257803.44","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.44","url":null,"abstract":"<p><strong>Background: </strong>Drug-related problems (DRPs) are prevalent among older cancer patients. This study aimed to investigate the impact of pharmaceutical services on DRP, disease knowledge, health-related quality of life, and satisfaction among older patients with prostate cancer (PCa).</p><p><strong>Methods: </strong>The clinical data of 86 elderly patients with PCa admitted during June 2021-June 2024 were retrospectively analyzed. Descriptive statistics and univariate analysis were used to evaluate the effectiveness of the clinical application of the pharmacy service carried out in our hospital, including the incidence of DRP, knowledge of disease, health-related quality of life score, and satisfaction. The general content of pharmaceutical services is as follows: Arrange hospital pharmacists to directly participate in patient treatment, conduct drug reviews, identify DRPs, and discuss with prescribing doctors based on problems to optimize medication plans. At the same time, it provides disease knowledge education, medication consultation, and primary care guidance.</p><p><strong>Results: </strong>At admission, 55 patients (63.95%) had DRP, with the most common classification being drug selection, with an incidence rate of 36.36% (20/55). At discharge, the proportion of DRP in patients receiving pharmaceutical services was lower than that in patients refusing pharmaceutical services, and the DRP status was better than that of patients refusing pharmaceutical services (<i>p</i> < 0.05). Patients who received pharmaceutical services had higher level of disease knowledge mastery (<i>p</i> < 0.001), Short-Form-36 (SF-36) score in some dimensions (<i>p</i> < 0.05), and satisfaction (<i>p</i> < 0.05) than those who refused pharmaceutical services.</p><p><strong>Conclusions: </strong>Hospital pharmaceutical services can effectively reduce the occurrence of DRP during hospitalization of elderly patients with PCa, help them to acquire knowledge of the disease and health-related quality of life, and have high patient satisfaction.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"325-333"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancing Quality of Life, Mental Health, and Treatment Adherence in Patients Who Had Undergone Radical Prostatectomy through an Internet-Supported Home-Based Rehabilitation Program.","authors":"Jie Zhao, Xin Wang, Ranran Shu, Feng Yang","doi":"10.56434/j.arch.esp.urol.20257803.42","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257803.42","url":null,"abstract":"<p><strong>Objective: </strong>Prostate cancer is a common global health concern, and enhancing patient outcomes and quality of life is essential. This study aimed to investigate the impact of an internet-supported home-based rehabilitation program on quality of life, psychological well-being, and treatment adherence in patients who had undergone radical prostatectomy.</p><p><strong>Methods: </strong>A total of 103 patients who underwent radical prostatectomy in our hospital from April 2020 to December 2023 were categorized into control and research groups based on whether they received an internet-supported family rehabilitation plan. The control group, consisting of 53 patients, received standard discharge instructions, while the research group, comprising 50 patients, received additional home rehabilitation care as part of their routine discharge instructions. The Generic Quality of Life Inventory-74 (GQOLI-74) is a comprehensive questionnaire used to assess and compare the two groups' quality of life before and after nursing care. The Self-Rating Anxiety Scale (SAS) and Self-Rating Depression Scale (SDS) assessed and compared mental health status pre- and post-nursing intervention. Treatment compliance, nursing satisfaction, and complications were monitored and compared between the groups.</p><p><strong>Results: </strong>There were no significant differences in age, Body Mass Index (BMI), disease duration, tumour stage, and other clinical variables between the two groups (<i>p</i> > 0.05). Before nursing care, GQOLI-74 scores did not differ significantly between the groups (<i>p</i> > 0.05). However, following nursing care, the research group exhibited substantially higher scores (<i>p</i> < 0.05) across all items than the control group. Similarly, there was no considerable difference in SDS and SAS scores between the two groups (<i>p</i> > 0.05) before nursing care. Post-intervention, SDS scores in the research group were significantly lower than those in the control group (<i>p</i> < 0.05), and treatment compliance scores were substantially higher in the research group (<i>p</i> < 0.05). Moreover, the incidence of complications was significantly lower in the research group compared to the control group (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>The internet-derived family rehabilitation program significantly improved patients' quality of life, psychological well-being, and treatment compliance, indicating its potential for clinical implementation.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 3","pages":"310-317"},"PeriodicalIF":0.6,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144004699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}