Archivos Espanoles De Urologia最新文献

{"title":"Examining the Association between ERG/PTEN Expression and Biochemical Recurrence in Prostate Cancer: A Comprehensive Meta-Analysis.","authors":"Weijun Zhu, Weifei Chen","doi":"10.56434/j.arch.esp.urol.20257801.4","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.4","url":null,"abstract":"<p><strong>Background: </strong><i>ETS</i>-related gene (<i>ERG</i>) rearrangement and tensin homolog (<i>PTEN</i>) deletion are common molecular alterations in prostate cancer. Their prognostic significance for biochemical recurrence (BCR) after radical prostatectomy is not fully understood. This study aimed to conduct a systematic review and meta-analysis to assess the association between <i>ERG</i> and <i>PTEN</i> status and BCR risk.</p><p><strong>Methods: </strong>We systematically searched PubMed, Embase, Web of Science, and the Cochrane Library for studies on <i>ERG</i>/<i>PTEN</i> status and BCR following radical prostatectomy. Pooled hazard ratios (HRs) and 95% confidence intervals (CIs) were calculated using fixed-effects and random-effects models to determine the risk associated with these biomarkers.</p><p><strong>Results: </strong>The meta-analysis showed that <i>ERG</i> positivity was linked to a 35.38% increased risk of BCR (HR = 1.3538 (0.9517; 1.9256), <i>p</i> = 0.0920) with significant heterogeneity (I² = 69.3%, <i>p</i> = 0.0001). In subgroup analysis, <i>ERG</i> positivity was associated with increased BCR risk in both Asian (HR = 2.2538) and Caucasian (HR = 1.4387) populations. <i>PTEN</i> loss was associated with an 83.73% higher BCR risk (HR = 1.8373, 95% CI: 1.6469-2.0496, <i>p</i> < 0.0001) with low heterogeneity (I² = 16.3%, <i>p</i> = 0.2974).</p><p><strong>Conclusions: </strong>Both <i>ERG</i> rearrangement and <i>PTEN</i> deletion are associated with an increased risk of BCR after radical prostatectomy. While these biomarkers may improve prognostic stratification, the prognostic value of <i>ERG</i> status varies across different populations, suggesting a need for personalized management strategies in prostate cancer based on molecular markers.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"25-36"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410955","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Relationship between the Composition of Urinary Calculi and Protein Biomarkers in Serum and Urine.","authors":"Xun Wang, Qiang Ma, Xuefeng Xie, Xueqiang Lu","doi":"10.56434/j.arch.esp.urol.20257801.11","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.11","url":null,"abstract":"<p><strong>Background: </strong>The present study aims to determine the relationship between the expression levels of serum and urine biomarkers, and the composition of urinary calculi, in order to provide additional background information on the disease.</p><p><strong>Methods: </strong>A total of 80 patients with urinary calculi, who were admitted to our hospital from January 2022 to June 2023, were selected as the study objects. In addition, 80 healthy subjects, who were admitted to our hospital during the same period, were selected as the control group. Patients with urinary calculi were further divided into two groups: Calcium oxalate calculi group and uric acid carbonate calculi group. The serum and urine biomarker levels of subjects in each group were compared by enzyme-linked immunosorbent assay. The correlation among calculi composition, clinical indicators, and protein biomarker levels was determined by single-factor and multi-factor analyses. The value of protein biomarkers in predicting calculi composition was evaluated using the receiver operating characteristic curve.</p><p><strong>Results: </strong>There were significant differences in the expression levels of Lipocalin-2, matrix metalloproteinase 8, matrix metalloproteinase 9, angiopoietin-like 3, Dickkopf-4, interleukin 10 receptor alpha, interleukin 1 receptor 5, interleukin 2 receptor subunit gamma chain, and interleukin 28 A between the experimental and control groups. Furthermore, serum and urine Dickkopf-4, urine interleukin 10 receptor alpha, and microscopic red blood cell levels in urine were higher in patients with calcium oxalate calculi, when compared to patients with uric acid carbonate calculi (<i>p</i> < 0.05). The receiver operating characteristic curve analysis revealed that the area under curve for the four indicators was 0.854, with a cut-off value of 0.742. Thus, this can be used to predict the calcium oxalate composition in calculi.</p><p><strong>Conclusions: </strong>Serum and urine protein biomarkers Dickkopf-4 and urine interleukin 10 receptor alpha, and microscopic red blood cells in urine can be used to predict the calculi composition. Patients with calcium oxalate calculi are more likely to have hematuria, when compared to patients with calculi of other compositions.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"84-92"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of the Efficacy of Transurethral Cystolithotripsy and Percutaneous Cystolithotomy in the Treatment of Male Children with 20-30 mm Bladder Stones: A Retrospective Study.","authors":"Yichun Xie, Mingchun Zhang, Ke Liu","doi":"10.56434/j.arch.esp.urol.20257801.9","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.9","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the clinical efficacy and safety of transurethral cystolithotripsy (TUCL) and percutaneous cystolithotomy (PCCL) in treating 20-30 mm bladder stones in male children.</p><p><strong>Methods: </strong>Data on 62 male children of ≤16 years of age who were admitted to our hospital with bladder stones between January 2020 and December 2023 were retrospectively collected. The patients were categorised into a TUCL group (TUCL, n = 32) and a PCCL group (PCCL, n = 30) according to the employed surgical method. Operative time, stone-free rate (SFR), complication incidence, and general information of the patients were compared between the two groups.</p><p><strong>Results: </strong>No significant differences in age, stone size, composition, and other general medical history were observed between the two groups (<i>p</i> > 0.05). SFR was 100% in both groups, but the operative time in the TUCL group was significantly longer than that in the PCCL group (<i>p</i> < 0.05). Furthermore, catheter indwelling time in the TUCL group was significantly shorter than that in the PCCL group (<i>p</i> < 0.05). No significant difference in the overall complication incidence was found between the two groups (<i>p</i> > 0.05), whereas the number of urinary retention cases was higher in the TUCL group than in the PCCL group.</p><p><strong>Conclusions: </strong>TUCL and PCCL are effective surgical methods for treating 20-30 mm bladder stones in male children. Compared to TUCL, PCCL may be the preferred option owing to its relatively shorter operative time and lower complication rate.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"71-76"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Postpartum Stress Urinary Incontinence: Current Advances in Non-Pharmacological Therapies.","authors":"Yanzhen Chen, Feifang Zhang, Pingwu Zheng, Dawei Cui, Xufei Fan","doi":"10.56434/j.arch.esp.urol.20257801.1","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.1","url":null,"abstract":"<p><p>Stress urinary incontinence (SUI) is a prevalent postpartum condition that significantly impacts women's quality of life and mental health. This systematic review synthesizes current advances in non-pharmacological therapies for postpartum SUI, focusing on pelvic-floor muscle training (PFMT), electrical and magnetic stimulation, acupuncture, and other therapies like Pilates and breathing exercises. Our literature search in PubMed, Cochrane Library, and Web Science identified studies examining these interventions, which are crucial for treating SUI due to their safety and efficacy. PFMT, also known as Kegel exercises, is the cornerstone of SUI treatment, enhancing pelvic-floor muscle strength and function. Electrical and magnetic stimulation is emerging as effective adjuncts to PFMT, improving muscle endurance and urinary control. Acupuncture, a traditional Chinese medicine therapy, shows promise in regulating pelvic-floor muscle function and is particularly appealing due to its safety and reliability. Pilates and breathing exercises are also considered, with evidence suggesting that they improve core strength and urinary incontinence symptoms when combined with PFMT. Despite the variety of treatments available, several questions remain, including the optimal duration of pelvic-floor electrical and magnetic stimulation, the potential synergistic effect of these stimulations with PFMT, and whether prolonged stimulation provides additional benefits. Future research should address patient compliance, long-term treatment effects, and the biological mechanisms underlying these therapies. A multimodal treatment approach may yield synergistic effects and improved outcomes. This review provides evidence to support clinical treatment recommendations and highlights areas for future research, aiming to optimize non-pharmacological treatment programs for postpartum SUI.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"1-9"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Triglyceride and Glucose Index is Associated with the Severity of Erectile Dysfunction.","authors":"Ozan Efesoy, Barış Saylam, Selahittin Çayan","doi":"10.56434/j.arch.esp.urol.20257801.3","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.3","url":null,"abstract":"<p><strong>Background: </strong>Insulin resistance resulting in endothelial dysfunction is related to erectile dysfunction. The triglyceride and glucose index is a low-cost, practical, and easily accessible parameter for determining insulin resistance. We aimed to reveal the relationship between the triglyceride and glucose index and the severity of erectile dysfunction.</p><p><strong>Methods: </strong>Medical records of 974 patients admitted to our clinic complaining of erectile dysfunction between January 2021 and June 2023 were scanned retrospectively from the database programme. According to the scores obtained from the simplified 5-item International Index of Erectile Function questionnaire, patients were classified into four groups: Group 1 (patients with severe erectile dysfunction), group 2 (patients with moderate erectile dysfunction), group 3 (patients with mild-to-moderate erectile dysfunction), and group 4 (patients with mild erectile dysfunction). We compared the fasting serum glucose, triglyceride, total cholesterol levels, and triglyceride and glucose indices (formula 1: Ln[fasting triglycerides (mg/dL) × fasting glucose (mg/dL)]/2), and formula 2: Ln[fasting triglycerides (mg/dL) × fasting glucose (mg/dL)/2]) of the patients in the groups.</p><p><strong>Results: </strong>No statistically significant differences in the mean age and serum total testosterone levels existed amongst the four groups (<i>p</i> = 0.695 and 0.074, respectively). A statistically significant difference was found in fasting serum glucose, triglyceride, and total cholesterol levels amongst the groups (<i>p</i> < 0.001). Significant negative correlations were found between the simplified 5-item International Index of Erectile Function questionnaire score and fasting serum glucose, triglyceride, total cholesterol, and triglyceride and glucose index (all <i>p</i> values < 0.001). The triglyceride and glucose index level was related to the risk of severe erectile dysfunction. Receiver operating characteristic curve analysis showed that the cutoff values were 5.05 for the triglyceride and glucose index by formula 1 and 9.43 for the triglyceride and glucose index by formula 2 in predicting severe erectile dysfunction.</p><p><strong>Conclusions: </strong>The triglyceride and glucose index may be associated with erectile dysfunction and also its severity.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"18-24"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Nomogram Diagnostic Utility in Prostate Cancer Staging: An Excellent Diagnostic Tool for Prostate Cancer Staging.","authors":"Zhaoyin Wang, Xianyou Wang, Zhenhua Yang, Yizhai Ye, Aizhu Sheng","doi":"10.56434/j.arch.esp.urol.20257801.13","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.13","url":null,"abstract":"<p><strong>Background/purpose: </strong>Prostate cancer is a prevalent malignancy with high incidence and mortality rates. Multiparametric magnetic resonance imaging (mpMRI) at 3.0Tesla (3.0T) offers high-resolution imaging to visualise tumour characteristics. This study aims to evaluate the diagnostic and staging utility of 3.0T mpMRI in prostate cancer.</p><p><strong>Methods: </strong>In this retrospective study, patients suspected of having prostate cancer and admitted to our hospital between March 2022 to March 2024 underwent 3.0T mpMRI and prostate biopsy. Patients were staged in accordance with TNM classification (Groups I-II and III-IV). The diagnostic accuracy of mpMRI was assessed using Prostate Imaging Reporting and Data System (PI-RADS) Version 2.1 scores, tumour characteristics, signal intensities, radiomic features and biomarker levels. Least absolute shrinkage and selection operator (LASSO), multivariate logistic regression and joint model analyses were employed to identify factors influencing cancer progression.</p><p><strong>Results: </strong>Amongst the 110 patients, 74 were in Groups I-II, and 36 in Groups III-IV. The diagnostic accuracy and sensitivity of mpMRI exceeded 90%. Significant differences were observed in Gleason scores, tumour size, location, volume, signal intensities, PI-RADS scores, radiomic features and biomarker levels (<i>p</i> < 0.05). LASSO regression analysis identified nine key variables, and logistic regression analysis revealed that Gleason scores, tumour size, PI-RADS score, apparent diffusion coefficient (ADC) values and prostate-specific antigen (PSA) levels were significantly associated with prostate cancer staging (<i>p</i> < 0.05). A predictive model was developed based on the five variables, and the receiver operating characteristic of 0.976 demonstrated excellent discriminatory power for the model. The calibration curve closely aligns with the diagonal line, indicating excellent calibration. Decision curve analysis shows net benefits across various threshold probabilities, highlighting its potential for informing clinical decision-making.</p><p><strong>Conclusions: </strong>This study developed a predictive model for prostate cancer staging using multiparametric MRI, radiomic features and clinical data, showing strong potential for early diagnosis and prognostic evaluation. Future advancements in imaging technology and machine learning techniques may further enhance its clinical impact.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"100-108"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411262","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intrarenal Ectopic Adrenal Tissue Mimics Renal Cell Carcinoma in the Kidney: A Clinicopathological Diagnostic Challenge.","authors":"Engin Telli, Büşra Yaprak Bayrak, Kerem Teke, Enes Malik Akdaş, Önder Kara","doi":"10.56434/j.arch.esp.urol.20257801.14","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.14","url":null,"abstract":"<p><strong>Background: </strong>Adrenal tissue can be found in different organs or systems of the body owing to developmental abnormalities. They may be functional or non-functional and are often discovered incidentally during imaging studies for other conditions. When located within or near the kidney, ectopic adrenal tissue can mimic renal cell carcinoma (RCC), posing a diagnostic challenge for clinicians.</p><p><strong>Methods: </strong>We reported the case of a 65-year-old male who presented with an asymptomatic renal mass mimicking RCC on preoperative imaging. Owing to the radiological suspicion of malignancy, laparoscopic partial nephrectomy was performed to ensure appropriate management.</p><p><strong>Results: </strong>The pathological examination of partial nephrectomy material showed findings compatible with adrenal tissue, and a diagnosis of ectopic intrarenal adrenal tissue was made. Immunohistochemical analysis confirmed the adrenal origin, with markers such as Melan-A and alpha-inhibin differentiating the lesion from RCC.</p><p><strong>Conclusions: </strong>The ectopic location of adrenal tissue, which is usually asymptomatic and benign, complicates diagnostic and therapeutic approaches. In cases with ambiguous imaging findings, intraoperative frozen biopsy may be considered, but surgery is often preferred when malignancy cannot be ruled out. This case highlights the importance of considering ectopic adrenal tissue in the differential diagnosis of renal masses, particularly when imaging findings are inconclusive. Therefore, multidisciplinary collaboration is essential to avoid unnecessary surgical interventions and ensure optimal patient care.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"109-112"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411036","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Impact of Preoperative Visits Using the Omaha System on Patients Undergoing Transurethral Resection of the Prostate: Improvement in Sleep Quality and Negative Psychological Aspects.","authors":"Miaomiao Geng, Chenghong Xiang, Jing Huang","doi":"10.56434/j.arch.esp.urol.20257801.7","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.7","url":null,"abstract":"<p><strong>Background: </strong>The Omaha System, recognised for its comprehensive approach that encompasses physical, psychosocial, and environmental factors, has shown promise in improving patient outcomes across various healthcare settings. This study aimed to investigate the impact of preoperative visits conducted using the Omaha System on patients undergoing transurethral resection of the prostate (TURP), with a specific focus on sleep quality and negative psychological aspects.</p><p><strong>Methods: </strong>A retrospective cohort study was conducted, including patients scheduled for TURP between March 2022 and March 2024. Patients were categorised into two groups based on the preoperative visit methods: Traditional preoperative visits and those utilising the Omaha System. A total of 120 patients were included in the study, with 68 patients experiencing traditional preoperative visits and 52 patients receiving visits using the Omaha System. Various parameters, including sleep quality, psychological aspects, and clinical characteristics, were assessed and analysed both preoperatively and postoperatively.</p><p><strong>Results: </strong>Preoperatively, there were no significant differences in sleep quality parameters or negative psychological aspects between the two groups. However, postoperatively, the group that received preoperative visits using the Omaha System demonstrated significant improvements in sleep quality, including the Pittsburgh Sleep Quality Index (PSQI) global score (<i>p</i> = 0.015), sleep latency (<i>p</i> = 0.043), sleep duration (<i>p</i> = 0.002), sleep efficiency (<i>p</i> = 0.004), and sleep disturbances (<i>p</i> = 0.004). Additionally, reductions in anxiety (<i>p</i> = 0.006), depression (<i>p</i> = 0.028), stress (<i>p</i> = 0.025), fear related to the surgery (<i>p</i> = 0.009), and uncertainty (<i>p</i> = 0.005) were observed postoperatively in the Omaha System group compared to the traditional visit group.</p><p><strong>Conclusions: </strong>The implementation of preoperative visits using the Omaha System significantly improved postoperative sleep quality and reduced negative psychological aspects among patients undergoing TURP.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"56-62"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411238","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Analysis of Factors Related to Urinary Tract Infections in Children with Nephrotic Syndrome and Preliminary Exploration of Treatment Strategies.","authors":"Wentao Jing, Jia Tao, Ye Cao, Huang Wang, Dong Qian","doi":"10.56434/j.arch.esp.urol.20257801.12","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.12","url":null,"abstract":"<p><strong>Objective: </strong>Nephrotic syndrome (NS) is a common disorder in children that significantly affects their health. Children with NS often suffer from urinary tract infections (UTIs), which are common complications that not only complicate treatment but also worsen prognosis. The aim of this study was to analyze the factors associated with UTIs in children with NS and investigate potential intervention strategies.</p><p><strong>Methods: </strong>Ninety-four pediatric patients with NS who were admitted to our hospital from January 2023 to October 2023 were selected. Among these patients, 34 children with UTIs were included in the research group, and the remaining 60 with NS alone were included in the control group. The children's clinical data, such as age, sex, and NS course, were collected. Factors affecting the occurrence of UTIs in children with NS were analyzed via logistic regression, and future treatment strategies were discussed. Furthermore, children with UTIs were analyzed for the presence of pathogenic bacteria to summarize the clinical profile of these pathogens.</p><p><strong>Results: </strong>Logistic regression analysis revealed that the duration of hormone use (odds ratio (OR): 3.841, 95% CI: 2.141-5.862), type of antibiotics used (OR: 1.841, 95% CI: 1.541-5.249), length of hospital stay (OR: 1.461, 95% CI: 1.124-1.667), albumin (ALB; OR: 0.623, 95% CI: 0.384-0.857, <i>p</i> = 0.015), immunoglobulin G (IgG; OR: 0.534, 95% CI: 0.264-0.836, <i>p</i> = 0.005), and 24-hour urine protein concentration (24 h Pro; OR: 6.242, 95% CI: 2.642-10.645) were independent relevant factors for UTIs in children with NS (<i>p</i> < 0.05). The analysis of pathogenic bacteria revealed that gram-negative bacteria were the most prevalent bacteria in children with UTIs (28 out of 34).</p><p><strong>Conclusions: </strong>In the future, in the clinical treatment of pediatric NS patients, it is necessary to strictly control the dosage of hormones and antibiotics and pay attention to the dynamic changes in the ALB, IgG, and 24 h Pro levels to prevent UTIs.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"93-99"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143411316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhancement in Perioperative Care Outcomes through Nurse-Led Multidisciplinary Team Care among Patients Undergoing da Vinci Robot-Assisted Radical Prostatectomy: A Retrospective Study.","authors":"Yubo Kang, Jiayu Tan, Qiongfang Zhu, Yang Li, Wenyan Wu, Zehui Wu, Yuwen He, Fengqiu Gong","doi":"10.56434/j.arch.esp.urol.20257801.8","DOIUrl":"https://doi.org/10.56434/j.arch.esp.urol.20257801.8","url":null,"abstract":"<p><strong>Objective: </strong>Clinically, prostate cancer (PCa) is a common cancer among males, with the primary treatment being radical prostatectomy, which, nevertheless, has side effects. Multidisciplinary team (MDT) care, a new nursing method, could facilitate accurate diagnosis and individualized treatment. This study explored the perioperative nursing effect of MDT on patients undergoing da Vinci robot-assisted radical prostatectomy.</p><p><strong>Methods: </strong>A total of 146 patients underwent radical resection of prostate cancer in The First Affiliated Hospital, Sun Yat-sen University from January 2023 to February 2024. They were divided into the MDT group (n = 77) and conventional care group (CC group, n = 69) according to the care modes; The data collected during the nursing period were collected and compared.</p><p><strong>Results: </strong>The baseline characteristics of the two groups before care were similar, showing no significant difference (<i>p</i> > 0.05). After the implementation of care, resuscitation chamber dwell time and the quality of life and anxiety scores at each stage were better in the MDT than in the CC group, and the difference was statistically significant (<i>p</i> < 0.05).</p><p><strong>Conclusions: </strong>Patients with radical resection of prostate cancer exhibit a high need for physical and psychological nursing. The implementation of a multidisciplinary nursing team led by nurses plays a major role in improving the anesthetic resuscitation effect while assisting in improving quality of life and anxiety.</p>","PeriodicalId":48852,"journal":{"name":"Archivos Espanoles De Urologia","volume":"78 1","pages":"63-70"},"PeriodicalIF":0.6,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143410730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}