Bioinspired Biomimetic and Nanobiomaterials最新文献_第4页

Nanomaterial reinforced composite for biomedical implants applications: a mini-review 纳米材料增强复合材料在生物医学植入物中的应用:综述

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2022-06-10 DOI: 10.1680/jbibn.21.00061

Manjeet Kumar, Rajesh Kumar, Sandeep Kumar

{"title":"Nanomaterial reinforced composite for biomedical implants applications: a mini-review","authors":"Manjeet Kumar, Rajesh Kumar, Sandeep Kumar","doi":"10.1680/jbibn.21.00061","DOIUrl":"https://doi.org/10.1680/jbibn.21.00061","url":null,"abstract":"There is heavy demand for suitable implant materials with improved mechanical and biological properties. Classically, the demand was catered by conventional materials like metals, alloys, and polymer-based materials. Recently, nanomaterial reinforced composites have played a significant role in replacing conventional materials due to their excellent properties such as biocompatibility, bioactivity, high strength to weight ratio, long life, corrosion & wear resistance, and tailor-ability. Herein, we composed a systematic focus review on the role of nanoparticles in the form of composite materials for the advancements in orthopedic implants. Several nano materials-based reinforcements have been reviewed with various matrix materials, including metals, alloys, ceramics, composites, and polymers for biomedical implant applications. Moreover, the improved biological properties, mechanical properties, and other functionalities like infection resistance, drug delivery at the target, sensing, and detection of bone diseases, and corrosion & wear resistance are elaborated. At last, a particular focus has been given to the un-resolved challenges in orthopedic implant development.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-06-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48389208","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Inspired by mussel: biomimetic polyelectrolyte complex coacervate adhesive initiates a connection through water exchange 灵感来自贻贝:仿生聚电解质复合物凝聚胶通过水交换启动连接

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2022-05-13 DOI: 10.1680/jbibn.21.00001

Guilong Wang, Zhen-Feng Hu, Xiu-Bing Liang, Fu-Xue Chen

引用次数: 0

Bioinspired, Biomimetic and Nanobiomaterials: Referees 2021 生物启发，仿生和纳米生物材料:裁判员2021

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2022-03-01 DOI: 10.1680/jbibn.2022.11.1.33

引用次数: 0

Fabrication of anisotropic superhydrophobic surface based on the Nepenthes slippery zone 基于Nepenthes滑带的各向异性超疏水表面的制备

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2022-02-23 DOI: 10.1680/jbibn.21.00042

Lixin Wang, Shaobo Ma, Shixing Yan, Shiyun Dong

{"title":"Fabrication of anisotropic superhydrophobic surface based on the Nepenthes slippery zone","authors":"Lixin Wang, Shaobo Ma, Shixing Yan, Shiyun Dong","doi":"10.1680/jbibn.21.00042","DOIUrl":"https://doi.org/10.1680/jbibn.21.00042","url":null,"abstract":"Depending on its highly evolved structures that consist of microscale lunate cells and nanoscale wax coverings, the slippery zone of Nepenthes alata shows significant anisotropic superhydrophobicity, which has gradually become the biomimetic prototype for designing superhydrophobic surfaces. In this study, the authors constructed the structures of the slippery zone into equidistantly distributed greenhouses and array of cylinders, therefore obtaining a biomimetic model of an anisotropic superhydrophobic surface. The greenhouses were printed using ultraviolet-cured material, via 3D printing, and then flake graphite was selected as a substitute for the array of cylinders (wax coverings) and was absorbed onto the printed greenhouses by using high-voltage electrostatic absorption technology. The contact/sliding angle was measured to verify the anisotropic superhydrophobic effect of the fabricated sample. The contact angle increases significantly with an increase in the greenhouse density (l/L value) and achieves a value of 152.6 ± 0.6° when l/L is 0.8, and the sliding angle toward bottom and top shows values of 3.07 ± 0.26° and 5.69 ± 0.24°, respectively. These results indicate that the fabricated sample has anisotropic superhydrophobicity. Therefore, this study provides a simple and low-cost approach for the biomimetic fabrication of anisotropic superhydrophobic surfaces.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138512655","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

3D Nanocomposite scaffold of TiO2 nanotubes incorporated carrageenan (TiO2NT/CG) for wound healing 含有角叉胶(TiO2 /CG)的TiO2纳米管三维纳米复合支架用于伤口愈合

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2022-02-17 DOI: 10.1680/jbibn.21.00054

Yong Gao, N. Ismail, M. Yusoff, M. Razali

{"title":"3D Nanocomposite scaffold of TiO2 nanotubes incorporated carrageenan (TiO2NT/CG) for wound healing","authors":"Yong Gao, N. Ismail, M. Yusoff, M. Razali","doi":"10.1680/jbibn.21.00054","DOIUrl":"https://doi.org/10.1680/jbibn.21.00054","url":null,"abstract":"3D nanocomposite scaffold is an important material for biomedical application owing to its compatibility and effectiveness compared with other types of nanocomposites. In this research, a unique 3D nanocomposite scaffold based on carrageenan biopolymer incorporating TiO2 nanotubes was successfully developed. Prior to the nanocomposite scaffold preparation, the TiO2 nanotubes as nanofiller were synthesized using the hydrothermal method. The synthesis of TiO2 nanotubes was incorporated into carrageenan for the fabrication of a 3D nanocomposite scaffold using the freeze-drying technique. The synthesized and fabricated materials were characterized using various techniques. Fourier-transform infrared spectroscopy and X-ray powder diffraction were employed to investigate the intermolecular interaction and phase structure of the fabricated TiO2 nanotubes incorporated carrageenan (TiO2NT/CG) 3D nanocomposite scaffold. The morphology and microstructure were via scanning electron microscopy and transmission electron microscopy. The ability of TiO2NT/CG 3D nanocomposite scaffold for wound healing was tested in vitro and in vivo. The in vitro study on 3T3 mouse fibroblast cells demonstrated that the number of cells increased up to 190 K per well. Meanwhile, in vivo studies on Sprague Dawley rat exhibited that a 100% cure rate of wounds was observed after 14 days. These are attributed to the presence of ∼10-nm TiO2 nanotubes that are homogeneously distributed onto the scaffold, as proven by scanning electron microscopy. The TiO2 nanotubes promote wound healing by generating reactive oxygen species to induce the fibroblast growth factor and for the formation of a new extracellular matrix. The interconnected porous structure and rough surface of the TiO2/GG 3D nanocomposite scaffold also support cell proliferation to expedite wound healing, thus offering a good candidate for wound-dressing application.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2022-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41558251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 1

Mechanical properties, microstructure and chemical composition of naked mole rat incisors 裸鼹鼠门牙的力学性能、微观结构及化学成分

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2021-12-22 DOI: 21.00004

Hongyan Qi, Guixiong Gao, Huixin Wang, Yunhai Ma, Hubiao Wang, Siyang Wu, Jiangtao Yu, Qinghua Wang

{"title":"Mechanical properties, microstructure and chemical composition of naked mole rat incisors","authors":"Hongyan Qi, Guixiong Gao, Huixin Wang, Yunhai Ma, Hubiao Wang, Siyang Wu, Jiangtao Yu, Qinghua Wang","doi":"21.00004","DOIUrl":"https://doi.org/21.00004","url":null,"abstract":"The naked mole rat incisors (NMRI) exhibit excellent mechanical properties, which make it a good prototype for design and fabrication of bionic mechanical systems and materials. In this work, we characterised the chemical composition, microstructure and mechanical properties of NMRI, and further compared these properties with the laboratory rat incisors (LRI). We found out that (i) Enamel and dentin are composed of organic matter, inorganic matter and water. The ratio of Ca/P in NMRI enamel is higher than that of LRI enamel. (ii) The dentin has a porous structure. The enamel has a three-dimensional reticular structure, which is more complex, regular and denser than the lamellar structure of LRI enamel. (iii) Enamel has anisotropy. Its longitudinal nano-hardness is greater than that of transverse nano-hardness, and both of them are higher than that of LRI enamel. Their nano-hardness and elastic modulus increase with the increase in distance from enamel-dentin boundary. The nano-hardness of dentin is smaller than that of enamel. The chemical composition and microstructure are considered to be the reasons for the excellent properties of NMRI. The chemical composition and unique microstructure can provide inspiration and guide for the design of bionic machinery and materials.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138512663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Contact angle of Nepenthes slippery zone: results from measurement and model analysis 荆草滑带接触角:测量与模型分析结果

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2021-12-22 DOI: 21.00019

Lixin Wang, Pan Pan, Shixing Yan, Shiyun Dong

{"title":"Contact angle of Nepenthes slippery zone: results from measurement and model analysis","authors":"Lixin Wang, Pan Pan, Shixing Yan, Shiyun Dong","doi":"21.00019","DOIUrl":"https://doi.org/21.00019","url":null,"abstract":"The slippery zone of Nepenthes alata depends on its highly evolved morphology and structure to show remarkable superhydrophobicity, which has gradually become a biomimetic prototype for developing superhydrophobic materials. However, the mechanism governing this phenomenon has not been fully revealed through a model analysis. In this paper, the superhydrophobicity of the slippery zone is studied by contact angle measurement, morphology/structure examination and model analysis. The slippery zone causes an ultrapure water droplet to produce a considerably high contact angle (155.11–158.30°) and has micro–nanoscale hierarchical structures consisting of lunate cells and wax coverings. According to the Cassie–Baxter equation and a self-defined infiltration coefficient, a model was established to analyse the effect of a structure characteristic on the contact angle. The analysis, result showed that the calculated contact angle (154.67–159.49°) was highly consistent with the measured contact angle, indicating that the established model can quantitatively characterise the relationship between the contact angle and the structure characteristic. The authors’ study provides some evidences to further reveal the superhydrophobic mechanism of the slippery zone of N. alata, as well as inspiring the biomimetic development of superhydrophobic surfaces.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138512654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Histopathological evaluation of amino acid capped silver nanoconjugates in albino mice 氨基酸覆盖银纳米偶联物在白化病小鼠中的组织病理学评价

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2021-12-22 DOI: 21.00033

Sarwar Allah Ditta, Atif Yaqub, Fouzia Tanvir, Rehan Ullah, Muhammad Rashid, Muhammad Bilal

{"title":"Histopathological evaluation of amino acid capped silver nanoconjugates in albino mice","authors":"Sarwar Allah Ditta, Atif Yaqub, Fouzia Tanvir, Rehan Ullah, Muhammad Rashid, Muhammad Bilal","doi":"21.00033","DOIUrl":"https://doi.org/21.00033","url":null,"abstract":"Various molecules may modify the surface chemistry of commonly used nanomaterials (NMs), resulting in the synthesis of novel and safer NMs. The current study was delineated to evaluate the in vivo toxicity profiling of the silver nanoconjugates (AgNCs) conjugated with different amino acids. The L-glycine capped-AgNCs exhibited toxicity and caused tissue damage, while L-cystine- and L-tyrosine-capped AgNCs showed protective effects against cadmium-induced toxicity. L-cystine-capped AgNCs performed well as compared to other amino-acid AgNCs. The level of serum creatinine, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase and blood urea increased (p < 0.05) in G2, G3 and G5 in comparison to G1 (control group), while an increase in bilirubin for G2 was statistically non-significant (p > 0.05). The ALT and AST elevated (p < 0.05) in G4; however, other serological parameters in G4 and G6 did not show any noticeable change in their values. Histological analysis showed disturbed and deformed cellular structures in liver and kidney tissues of G2, G3 and G5. However, G4 and G6 samples demonstrated minute changes in comparison to G1. It is concluded that L-cystine- and L-tyrosine-capped AgNCs exhibited protective effects and should be tested further for developing safer nanoconjugates for biomedical uses.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138512662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Formulation of Nanoemulgel from Extracts of Musa acuminata: In-Vitro Kinetics and Antimicrobial Studies 穆萨提取物制备纳米乳胶凝胶的体外动力学及抗菌作用研究

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2021-12-15 DOI: 10.1680/jbibn.21.00026

Gaanapriya Veeramani, S. Murugaiyan, T. Marimuthu

引用次数: 0

Fluorophosphate bio-glass for bone tissue engineering: in vitro and in vivo study 骨组织工程用氟磷酸盐生物玻璃:体外和体内研究

4区工程技术

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2021-12-15 DOI: 21.00025

Pugalanthipandian Sankaralingam, Poornimadevi Sakthivel, Priscilla Andinadar Subbiah, Abirami Periyasamy, Jenifa Begam Rahumathullah, Vijayakumar Chinnaswamy Thangavel

{"title":"Fluorophosphate bio-glass for bone tissue engineering: in vitro and in vivo study","authors":"Pugalanthipandian Sankaralingam, Poornimadevi Sakthivel, Priscilla Andinadar Subbiah, Abirami Periyasamy, Jenifa Begam Rahumathullah, Vijayakumar Chinnaswamy Thangavel","doi":"21.00025","DOIUrl":"https://doi.org/21.00025","url":null,"abstract":"The objective of the work is to investigate the influence of fluoride in the bioactivity of phosphate bio-glass to utilise in bone tissue engineering. The fluorophosphate bio-glass system was formulated by varying fluoride content in phosphate-based glass 45P2O5-(30-X)-CaO-25Na2O-XCaF2 (X = 0, 1.25, 2.5, 3.75, and 5.0) using melt quenching technique. The elemental composition and fluoride retention in the prepared material was investigated by X-ray photoelectron spectroscopy. The bioactivity test in simulated body-fluid (SBF) exhibited apatite layer and its bone bonding ability which was characterized by X-ray diffraction patterns and Fourier Transform Infrared Spectrophotometer spectra. The viability of human gastric adenocarcinoma (AGS) and MG-63 cells of the bio-glass confirmed the nontoxic nature. In vivo studies demonstrated the conversion of the fluorophosphate glass to bone in the femoral condyle of the rabbit. After ten weeks, scanning electron microscope with energy dispersive X-ray spectrograph (SEM_EDAX) and confocal laser scanning microscopy examinations revealed the resorption rate and bone-glass interface qualitatively and quantitatively. Consequently, the biocompatible and bioresorbable nature of the fluorophosphate bioglass can be exploited as a potential bone graft substitute in the near future.","PeriodicalId":48847,"journal":{"name":"Bioinspired Biomimetic and Nanobiomaterials","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138512658","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"工程技术","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0