Nanomaterial reinforced composite for biomedical implants applications: a mini-review

IF 1.3 4区工程技术 Q4 ENGINEERING, BIOMEDICAL

Bioinspired Biomimetic and Nanobiomaterials Pub Date : 2022-06-10 DOI:10.1680/jbibn.21.00061

Manjeet Kumar, Rajesh Kumar, Sandeep Kumar

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引用次数: 0

Abstract

There is heavy demand for suitable implant materials with improved mechanical and biological properties. Classically, the demand was catered by conventional materials like metals, alloys, and polymer-based materials. Recently, nanomaterial reinforced composites have played a significant role in replacing conventional materials due to their excellent properties such as biocompatibility, bioactivity, high strength to weight ratio, long life, corrosion & wear resistance, and tailor-ability. Herein, we composed a systematic focus review on the role of nanoparticles in the form of composite materials for the advancements in orthopedic implants. Several nano materials-based reinforcements have been reviewed with various matrix materials, including metals, alloys, ceramics, composites, and polymers for biomedical implant applications. Moreover, the improved biological properties, mechanical properties, and other functionalities like infection resistance, drug delivery at the target, sensing, and detection of bone diseases, and corrosion & wear resistance are elaborated. At last, a particular focus has been given to the un-resolved challenges in orthopedic implant development.

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纳米材料增强复合材料在生物医学植入物中的应用:综述

对具有改进的机械和生物性能的合适的植入材料有很大的需求。传统上，金属、合金和聚合物基材料等传统材料满足了需求。近年来，纳米材料增强复合材料以其优异的生物相容性、生物活性、高强度重量比、长寿命、耐腐蚀耐磨性和可定制性等性能，在取代传统材料方面发挥了重要作用。在此，我们对复合材料形式的纳米颗粒在骨科植入物发展中的作用进行了系统的重点综述。综述了几种基于纳米材料的增强材料，包括用于生物医学植入应用的金属、合金、陶瓷、复合材料和聚合物。此外，还阐述了改进的生物特性、机械特性和其他功能，如抗感染性、靶向药物递送、骨骼疾病的传感和检测以及耐腐蚀和耐磨性。最后，特别关注骨科植入物开发中尚未解决的挑战。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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来源期刊

Bioinspired Biomimetic and Nanobiomaterials ENGINEERING, BIOMEDICAL-MATERIALS SCIENCE, BIOMATERIALS

CiteScore

2.20

自引率

0.00%

发文量

期刊介绍： Bioinspired, biomimetic and nanobiomaterials are emerging as the most promising area of research within the area of biological materials science and engineering. The technological significance of this area is immense for applications as diverse as tissue engineering and drug delivery biosystems to biomimicked sensors and optical devices. Bioinspired, Biomimetic and Nanobiomaterials provides a unique scholarly forum for discussion and reporting of structure sensitive functional properties of nature inspired materials.