International Journal of Chronic Obstructive Pulmonary Disease最新文献

{"title":"The Impact of Case Management on Elderly Patients with Chronic Obstructive Pulmonary Disease.","authors":"Na Li, Wenjing Wang, Yinyin Lv, Caihong Li, Xiangdong Mu","doi":"10.2147/COPD.S517564","DOIUrl":"https://doi.org/10.2147/COPD.S517564","url":null,"abstract":"<p><strong>Purpose: </strong>This study aims to investigate the effects of case management on elderly patients with chronic obstructive pulmonary disease (COPD) and compare changes in pulmonary function indicators, quality of life, dyspnea, and inhaled medication adherence before and after case management.</p><p><strong>Patients and methods: </strong>A total of 199 elderly COPD patients were enrolled from Beijing Tsinghua Changgung Hospital between January 2020 and November 2023. We implemented case management programs including regular patient education, personalized interventions, continuous support systems, and timely feedback mechanisms, and subsequently collected patient data at 1, 3, 6, and 12 months after initiating case management.</p><p><strong>Results: </strong>After one year of case management, pulmonary function indicators (FEV₁/FVC, FEV₁, FEV₁%pred, MMEF75/25 and MMEF75/25%) in elderly patients with COPD showed significant improvement (P < 0.001). The CAT score decreased from 17.96±6.57 (mean ± standard deviation) to 11.80±6.50, and mMRC score decreased from 2.35±0.66 to 1.14±0.92 (p<0.001). Additionally, 77.9% (155/199) of patients were able to maintain their use of the inhaler for 1 year.</p><p><strong>Conclusion: </strong>This study confirmed the significant role of case management in improving respiratory function, quality of life, and dyspnea in elderly patients with COPD. These findings not only provide a valuable reference for clinicians and patients, but also provide a strong foundation for further optimization of management strategies for elderly patients with COPD.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1407-1417"},"PeriodicalIF":2.7,"publicationDate":"2025-05-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12068385/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144002586","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long Term Efficacy and Safety of Bronchoscopic Thermal Vapor Ablation in Patients with COPD: A Retrospective Study of 50 Patients.","authors":"Barak Pertzov, Merav Ben Avraham, Eldar Priel, Lev Freidkin, Dror Rosengarten, Mordechai Reuven Kramer","doi":"10.2147/COPD.S518270","DOIUrl":"https://doi.org/10.2147/COPD.S518270","url":null,"abstract":"<p><strong>Background: </strong>Bronchoscopic Thermal Vapor Ablation (BTVA) has demonstrated improvements in FEV1 and quality of life in clinical trials. However, the long-term benefits and overall efficacy of this procedure remain uncertain and are not yet fully established.</p><p><strong>Methods: </strong>We conducted a retrospective observational study of all patients who underwent BTVA at Rabin Medical Center, Israel. The primary outcome was the change in FEV₁ from baseline. Secondary outcomes included other pulmonary function parameters and procedural adverse events.</p><p><strong>Results: </strong>A total of 50 patients were included in the study. The mean FEV1 values at baseline, 6 months, and 12 months post-procedure (n=31) were 0.74±0.21 L, 0.93±0.32 L, and 0.85±0.25 L, respectively (overall P<0.001; pairwise comparisons: baseline to 6 months, P<0.001; baseline to 12 months, P=0.016). The mean FVC values at baseline, 6 months, and 12 months post-procedure (n=31) were 1.97±0.56 L, 2.27±0.71 L, and 2.14±0.68 L, respectively (overall P=0.003; pairwise comparisons: baseline to 6 months, P=0.002; baseline to 12 months, P=0.125). Post-procedural complications included pneumonia in 5 patients (11%), of whom 3 developed necrotizing pneumonia and subsequently died, resulting in a 6% post-procedural mortality rate in the entire cohort. Hemoptysis was reported in 1 patient (2%).</p><p><strong>Conclusion: </strong>Bronchoscopic thermal vapor ablation is a minimally invasive bronchoscopic intervention for lung volume reduction. The procedure was associated with significant improvements in FEV₁ at 6 to 12 months and in FVC at 6 months, followed by a gradual decline over 12 to 24 months. Further research is warranted to optimize patient selection, enhance procedural safety, and assess long-term efficacy.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1387-1394"},"PeriodicalIF":2.7,"publicationDate":"2025-05-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12067720/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065065","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Construction and Validation of an Early Warning Model for Predicting the 28-Day Mortality in Sepsis Patients with Chronic Obstructive Pulmonary Disease.","authors":"Xiaoyuan Yu, Zihan Jiao, Fan Yang, Qi Xin","doi":"10.2147/COPD.S521816","DOIUrl":"https://doi.org/10.2147/COPD.S521816","url":null,"abstract":"<p><strong>Background: </strong>In the intensive care unit (ICU), approximately 45.6% of patients diagnosed with chronic obstructive pulmonary disease (COPD) also presented with sepsis, and this cohort exhibited a significantly higher 28-day mortality rate compared to sepsis patients without COPD (23.6% versus 16.4%). A novel nomogram is necessary to predict the risk of mortality within 28 days for sepsis patients with COPD.</p><p><strong>Methods: </strong>Clinical data from 501 sepsis patients with COPD were sourced from the MIMIC-IV database. These data were randomly allocated into a training cohort and a validation cohort in a 3:1 ratio. Independent predictors of 28-day mortality were identified through both univariate and multivariate logistic regression analyses. Subsequently, a nomogram model was developed, and its performance was assessed using receiver operating characteristic (ROC) curve analysis, calibration plots, and decision curve analysis.</p><p><strong>Results: </strong>The 28-day mortality rates in the training and validation cohorts were 32.7% and 27.2%, respectively. Multivariate regression analysis identified age, heart rate (HR), respiratory rate (RR), blood urea nitrogen (BUN), creatinine (Cr), lactate levels, pH, and urine output as independent risk factors for 28-day mortality in sepsis patients with COPD. Furthermore, the nomogram demonstrated superior predictive performance, with an area under the curve (AUC) of 0.784 for the training group and 0.689 for the validation group.</p><p><strong>Conclusion: </strong>This nomogram integrates laboratory indicators pertinent to the patient's metabolic status, hypoxia status, and organ function, thereby enhancing the accuracy of early prediction of 28-day mortality in sepsis patients with COPD. Additionally, the model's comparative advantage over existing scoring systems (eg, SOFA) would enhance its impact. Our findings hold substantial implications for early prognostic assessment and clinical decision-making in this patient population. Therefore, earlier diagnosis within 24 hours of admission and proper identification of high-risk patients may reduce disease-related mortality by promoting timely treatment.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1373-1385"},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065467/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144065062","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Role of Computed Tomography and Artificial Intelligence in Evaluating the Comorbidities of Chronic Obstructive Pulmonary Disease: A One-Stop CT Scanning for Lung Cancer Screening.","authors":"Xiaoqing Lin, Ziwei Zhang, Taohu Zhou, Jie Li, Qianxi Jin, Yueze Li, Yu Guan, Yi Xia, Xiuxiu Zhou, Li Fan","doi":"10.2147/COPD.S508775","DOIUrl":"https://doi.org/10.2147/COPD.S508775","url":null,"abstract":"<p><p>Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide. Comorbidities in patients with COPD significantly increase morbidity, mortality, and healthcare costs, posing a significant burden on the management of COPD. Given the complex clinical manifestations and varying severity of COPD comorbidities, accurate diagnosis and evaluation are particularly important in selecting appropriate treatment options. With the development of medical imaging technology, AI-based chest CT, as a noninvasive imaging modality, provides a detailed assessment of COPD comorbidities. Recent studies have shown that certain radiographic features on chest CT can be used as alternative markers of comorbidities in COPD patients. CT-based radiomics features provided incremental predictive value than clinical risk factors only, predicting an AUC of 0.73 for COPD combined with CVD. However, AI has inherent limitations such as lack of interpretability, and further research is needed to improve them. This review evaluates the progress of AI technology combined with chest CT imaging in COPD comorbidities, including lung cancer, cardiovascular disease, osteoporosis, sarcopenia, excess adipose depots, and pulmonary hypertension, with the aim of improving the understanding of imaging and the management of COPD comorbidities for the purpose of improving disease screening, efficacy assessment, and prognostic evaluation.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1395-1406"},"PeriodicalIF":2.7,"publicationDate":"2025-05-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144057925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing the Causal Relationship between Chronic Obstructive Pulmonary Disease and Tuberculosis: A Mendelian Randomization Study.","authors":"Zhuo Wang, Shuang Zhao, Yiwu Zhou, Yanqi He","doi":"10.2147/COPD.S511734","DOIUrl":"https://doi.org/10.2147/COPD.S511734","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) and tuberculosis are both significant global public health challenges. The co-occurrence of these two diseases is frequently observed in clinical settings. However, their causal relationship remains unclear.</p><p><strong>Methods: </strong>We utilized genome-wide association study (GWAS) datasets to conduct bidirectional two-sample Mendelian randomization and multivariable Mendelian randomization analyses. We first analyzed COPD data from the FinnGen consortium (n = 193,638) and tuberculosis data from a genetic association study (n = 484,598). In the second phase, we stratified COPD patients by age into the EARLY COPD group (Event_Age < 65) and the LATER COPD group (Event_Age ≥ 65) to explore their causal relationships with tuberculosis separately. We then validated these results using tuberculosis data from MRC-IEU (n = 462,933). Finally, smoking and COPD-related SNPs as instrumental variables were analyzed by multivariable Mendelian randomization to further investigate the association between COPD and tuberculosis. Multiple methods were used in the Mendelian analyses to ensure a comprehensive and rigorous investigation.</p><p><strong>Results: </strong>In the initial analysis phase utilizing the inverse variance weighting (IVW) method, tuberculosis showed no significant contribution to the incidence of COPD (IVW odds ratio (OR) = 0.9961; 95% confidence interval (CI) = 0.9828-1.0095; P = 0.564). Conversely, COPD appeared to significantly increase the risk of developing tuberculosis (IVW OR = 1.0008; 95% CI = 1.0001-1.0014; P = 0.015), particularly in patients under 65 (IVW OR = 1.0008; P = 0.011).</p><p><strong>Conclusion: </strong>This Mendelian randomization analysis found that COPD may increase the risk of tuberculosis, while tuberculosis does not increase the risk of COPD, suggesting the necessity of enhancing prevention and screening efforts for tuberculosis among COPD patients, especially younger individuals.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1361-1371"},"PeriodicalIF":2.7,"publicationDate":"2025-05-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12065539/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144026336","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Body Mass Index and Lung Function in Hospitalized Severe AECOPD Patients: Investigating Nonlinear Associations and the Role of Hemoglobin.","authors":"Cong Zhang, Wenhao Ling, He Pan, Rui Bai, Li He","doi":"10.2147/COPD.S521112","DOIUrl":"https://doi.org/10.2147/COPD.S521112","url":null,"abstract":"<p><strong>Background: </strong>Chronic obstructive pulmonary disease (COPD) is a leading cause of global morbidity and mortality. Patients hospitalized with severe acute exacerbations of COPD (AECOPD) represent a high-risk group with poor outcomes and accelerated lung function decline. Body mass index (BMI) shows inconsistent associations with lung function across populations, and its role in AECOPD remains unclear. Understanding this relationship may improve clinical management. Hemoglobin (Hb), essential for oxygen transport, may further influence this association through physiological mechanisms. This study aimed to explore the relationship between BMI and lung function in hospitalized patients with severe AECOPD and to assess whether BMI influences length of hospital stay (LOHS), while evaluating the potential modifying role of Hb.</p><p><strong>Methods: </strong>A retrospective, single-center cross-sectional study was conducted among 579 patients hospitalized for severe AECOPD from 2021 to 2023. Data on BMI, lung function, Hb levels, and LOHS were collected. Nonlinear and threshold effect analyses were used to explore associations between BMI and lung function or LOHS. Subgroup analyses assessed the modifying effect of Hb.</p><p><strong>Results: </strong>BMI exhibited a nonlinear positive association with FEV1, FVC, FEV1% predicted, and FVC% predicted. Thresholds were identified at 25.39 kg/m² for FEV1, 26.23 kg/m² for FEV1% predicted, 21.67 kg/m² for FVC, and 22.19 kg/m² for FVC% predicted. The association was more pronounced in patients with higher Hb levels. No significant association was found between BMI and LOHS, suggesting that other factors such as infection severity, comorbidities, or treatment strategies may may exert greater influence.</p><p><strong>Conclusion: </strong>A nonlinear, inverse L-shaped association was observed between BMI and lung function, further modified by Hb levels. These findings highlight the importance of individualized treatment and stratification strategies in severe AECOPD. Future longitudinal studies are needed to validate these observations.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1309-1320"},"PeriodicalIF":2.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12052015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144054440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Impact of Laboratory-Derived Frailty Index on Clinical Outcomes in Critical Care Patients with COPD: A Retrospective Analysis Using the MIMIC-IV Database.","authors":"Zhihu Zhou, Yixing He, Qianqian Wang, Jian Li, Yi Yu","doi":"10.2147/COPD.S518633","DOIUrl":"https://doi.org/10.2147/COPD.S518633","url":null,"abstract":"<p><strong>Background and objective: </strong>Chronic obstructive pulmonary disease (COPD) is associated with high mortality and morbidity worldwide. Notably, 20% of COPD patients are admitted to the ICU, and among them, there is a 25% mortality rate. Therefore, identifying novel risk factors for effective intervention is crucial for managing COPD. This research aims to investigate the relationship between the physiological and laboratory - based frailty index (FI - Lab) and mortality among critical care patients with COPD.</p><p><strong>Methods: </strong>The FI-Lab was constructed using 33 items. This index was used to quantify the frailty level of critically ill patients with COPD in the ICU. We analyzed data from the Medical Information Mart for Intensive Care-IV (MIMIC-IV) database. Our study group consisted of 6825 COPD patients with an average age of 65.8 ± 14.8 years, and 52.2% of them were male. The primary outcomes were 30-day and 90-day mortality rates. Multivariable Cox regression was used for statistical analysis. Propensity score matching (PSM) was applied to ensure robustness.</p><p><strong>Results: </strong>In total, 6825 patients were included in the study, and the PSM cohort had 1282 patients. Both continuous and categorical increases in the FI-Lab were significantly associated with higher mortality (<i>P</i> < 0.001). These results were further validated by PSM. Subgroup analyses corroborated these findings. Restricted cubic splines illustrated a linear relationship between the FI-Lab and mortality. Kaplan-Meier analysis revealed significantly reduced 90-day survival with increasing FI-Lab (Log rank test, <i>P</i> < 0.001).</p><p><strong>Conclusion: </strong>Elevated FI-Lab is an independent predictor of increased mortality in critical care patients with COPD. Further randomized controlled trials are required to confirm these results and refine patient management strategies.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1335-1346"},"PeriodicalIF":2.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12053783/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144035676","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of 12 weeks of Head-Down Strong Abdominal Breathing Training on Gait and Cognitive Function in Patients with Chronic Obstructive Pulmonary Disease.","authors":"Feiyun Song, Kexin Ding, Wen Sun, Qiong Huang, Ruichen Jiang, Heping Xiang, Mingyun Sun","doi":"10.2147/COPD.S514766","DOIUrl":"https://doi.org/10.2147/COPD.S514766","url":null,"abstract":"<p><strong>Background: </strong>As chronic obstructive pulmonary disease (COPD) progresses, it can limit physical activity, resulting in reduced mobility. And patients with COPD have a higher incidence of cognitive impairment compared to normal individuals. The aim of this study was to investigate the effect of breathing training in COPD patients' gait and cognitive function by changing the body position.</p><p><strong>Study design and methods: </strong>Eighty-three COPD patients were recruited and randomized (1:1:1) into a head-down strong abdominal breathing training group (HDBT), a head-down training group (HDT), and a strong abdominal breathing training group (BT). Cognitive function and gait performance were assessed after the intervention by comparing patients' stride frequency, stride length, step speed and Montreal cognitive assessment(MoCA) scores.</p><p><strong>Results: </strong>63 patients completed this study. After 12 weeks, in terms of Obstacle walking tasks gait, the HDBT group significantly improved the performance of COPD patients in obstacle walking tasks in terms of stride length (73.29±0.64, P<0.001), step speed (97.73±0.47, P=0.018) performance. At the same time, we also found that there was no statistical difference in the gait performance of each group in the walking task (P > 0.05). In terms of cognition, cognitive function scores(MoCA) were significantly higher in HDBT (P<0.001) HDT (P<0.001), and BT (P<0.001) compared to baseline.</p><p><strong>Conclusion: </strong>A 12-week HDBT program elevated cognitive function and improved stride length and speed metrics during an obstacle walking task in patients with stable COPD.</p><p><strong>Clinical trial registration number: </strong>chictr2400080452(30/01/2024).</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1347-1359"},"PeriodicalIF":2.7,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12051985/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053518","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development and Psychometric Evaluation of an Instrument to Assess Physical Activity Participation Behavior Among Chinese Patients with Chronic Obstructive Pulmonary Disease.","authors":"Yuanyu Liao, Huan Wang, Yuxin Zhan, Yunfang Liu, Weiwei Wang, Hui Ke, Fenfen Lan, Qiongge Zhi, Wang Li, Jiaohua Yu","doi":"10.2147/COPD.S511061","DOIUrl":"10.2147/COPD.S511061","url":null,"abstract":"<p><strong>Purpose: </strong>This study aimed to develop and evaluate a psychometrically reliable tool specifically designed to assess physical activity participation behavior in COPD patients in China.</p><p><strong>Patients and methods: </strong>Using the Motivation-Opportunity-Ability (MOA) model as a framework, a scale was developed and evaluated through literature and guideline reviews, qualitative research, interdisciplinary expert consultations (n=21), and a pilot trial (n=50). A sample of COPD patients diagnosed over a year was randomly divided into two groups for exploratory factor analysis (EFA) and confirmatory factor analysis (CFA) to test the factor structure. The scale's content validity, internal consistency and test-retest reliability were further assessed.</p><p><strong>Results: </strong>433 COPD patients from four hospitals in a city in China participated in this study. The final scale included 32 items and demonstrated good internal consistency, with a Cronbach's α of 0.956 and a test-retest reliability of 0.777. The EFA identified four dimensions, with factor loadings ranging from 0.530 to 0.799, explaining 60.338% of the total variance: Motivation (5 items), Opportunity (12 items), Ability (9 items), and Behavior (6 items). The CFA confirmed that the four-dimensional model fit the data well: χ²/df = 1.891, standardized root mean residual (SRMR) = 0.0497, root mean square error of approximation (RMSEA) = 0.064, comparative fit index (CFI) = 0.927, Tucker-Lewis index (TLI) = 0.921.</p><p><strong>Conclusion: </strong>The Physical Activity Participation Behavior Scale for COPD patients demonstrated good reliability and validity and can be used to assess physical activity participation in individuals with COPD.</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1321-1334"},"PeriodicalIF":2.7,"publicationDate":"2025-04-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12050208/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge of and Attitudes Towards Standard Care in Patients with COPD.","authors":"Maximilian Zimmermann, Charlotte Maria von Plessen, Doreen Kroppen, Sarah B Stanzel, Melanie Berger, Maximilian Wollsching-Strobel, F Feldmeyer, Cornelius Kellner, Tim Mathes, Wolfram Windisch, Daniel S Majorski","doi":"10.2147/COPD.S489395","DOIUrl":"https://doi.org/10.2147/COPD.S489395","url":null,"abstract":"<p><strong>Objective: </strong>Health-related-quality-of-life is frequently reduced following intensive care treatment. Unwarranted or unwanted therapeutic interventions should be avoided at all costs. Since COPD patients are often faced with difficult decisions, an assessment was made of their desire for disease education. Our aim was to identify patients understanding of their disease and what their attitudes are towards different treatment options and whether this correlates to demographic factors.</p><p><strong>Methods: </strong>The COPD-Assessment-Test (CAT) was used to measure subjective disease burden. The COPD-Questionnaire (COPD-Q) was used to assess subjects' own knowledge of their disease. In addition, a specifically designed questionnaire was used to assess patient's subjective level of desire to be educated on COPD-specific topics. A multiple linear regression analysis was performed to identify the demographic factors associated with a greater desire for disease-specific information.</p><p><strong>Results: </strong>127 patients (67.2±8.8 years) were prospectively enrolled. Mean CAT score was 21.3±8.9 (95% CI:1-40). The desire for medical consultation was highly individual. In terms of vaccination, 31.5% of patients wished for more information while 34.6% wished for less. This also held true for information on long-term pharmacological therapy (29.1% vs 30.7%, respectively). Information on behaviour in case of emergencies as well as smoking cessation were wished for 38% and 42% of patients, respectively. Results of the COPD-Q showed that subjects were well-informed about specific topics (vaccination, etiology, emergency-inhaler) and less informed about long-term pharmacotherapy. In linear regression analyses, age (p=0.086), sex (p=0.906), education (p=0.833), health literacy (p=0.336) and burden of disease (p=0.296) did not influence patients´ desire for disease-specific information.</p><p><strong>Conclusion: </strong>Based on our cohort, COPD patients wish for more medical information related to behaviour in emergency situations and smoking cessation. The desire for education on disease-specific topics did not naturally correlate with demographic characteristics. The provision of medical information to patients remains a highly individualized and essential part of patient care.</p><p><strong>Trial registration: </strong>German Clinical Trials Registry (DRKS00022109).</p>","PeriodicalId":48818,"journal":{"name":"International Journal of Chronic Obstructive Pulmonary Disease","volume":"20 ","pages":"1287-1297"},"PeriodicalIF":2.7,"publicationDate":"2025-04-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12049109/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144041148","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}