Korean Journal of Internal Medicine最新文献_第7页

Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016-2019. 韩国成年人口腔健康与高尿酸血症之间的关系：2016-2019年韩国国民健康与营养调查》。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-22 DOI: 10.3904/kjim.2023.425

Junyong Park, Minkook Son, Sung Won Lee, Won Tae Chung, Sang Yeob Lee

{"title":"Association between oral health and hyperuricemia in Korean adults: Korea National Health and Nutrition Examination Survey 2016-2019.","authors":"Junyong Park, Minkook Son, Sung Won Lee, Won Tae Chung, Sang Yeob Lee","doi":"10.3904/kjim.2023.425","DOIUrl":"10.3904/kjim.2023.425","url":null,"abstract":"Background/aims: Hyperuricemia plays an essential role in the gout. Despite the clinical significance of hyperuricemia, a direct relationship between oral health and hyperuricemia has not been established. We aim to investigate the association between oral health and hyperuricemia.Methods: We selected 17,557 subjects from the Korea National Health and Nutrition Examination Survey database for the years 2016-2019. Oral health-related variables included the number of dental caries, regular tooth brushing, use of secondary oral products, and regular dental examinations. The odds ratio (OR) and 95% confidence intervals (CIs) for hyperuricemia were calculated using a multivariable-adjusted logistic regression model.Results: Oral health status with dental caries and oral health behaviors, including tooth brushing, secondary oral products, and regular dental examination, were significantly associated with hyperuricemia in all participants. The adjusted OR and 95% CIs for hyperuricemia comparing more than three dental caries with no dental caries were 1.28 (1.08-1.52). The adjusted OR and 95% CIs for hyperuricemia in regular tooth brushing, use of secondary oral products, and regular dental examination were 0.78 (0.67-0.91), 0.91 (0.83-1.00), and 0.86 (0.78-0.95), respectively. Notably, the association between oral health and hyperuricemia was more prominent in male subjects. In addition, when subjects were grouped by the oral health scoring system, the prevalence of hyperuricemia was lower in groups with better oral health scores.Conclusion: We demonstrated that oral health status and behaviors are associated with hyperuricemia, particularly in males. Further studies are necessary to confirm the association between oral health and hyperuricemia.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"1001-1010"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569917/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478327","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Tight junction protein changes in irritable bowel syndrome: the relation of age and disease severity. 肠易激综合征中紧密连接蛋白的变化：年龄与疾病严重程度的关系。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 DOI: 10.3904/kjim.2024.097

Sang Un Kim, Ji A Choi, Man-Hoon Han, Jin Young Choi, Ji Hye Park, Moon Sik Kim, Yong Hwan Kwon

{"title":"Tight junction protein changes in irritable bowel syndrome: the relation of age and disease severity.","authors":"Sang Un Kim, Ji A Choi, Man-Hoon Han, Jin Young Choi, Ji Hye Park, Moon Sik Kim, Yong Hwan Kwon","doi":"10.3904/kjim.2024.097","DOIUrl":"10.3904/kjim.2024.097","url":null,"abstract":"Background/aims: The etiology of irritable bowel syndrome (IBS) is associated with intestinal mucosal barrier damage. However, changes in the tight junction (TJ) proteins in IBS have not been fully elucidated. This study aimed to evaluate TJ protein changes in IBS patients and the relationship between aging and disease severity.Methods: Thirty-six patients with IBS fulfilling the Rome IV criteria and twenty-four controls were included. To evaluate the change of TJ in the colonic mucosa, quantitative reverse transcription polymerase chain reaction, western blot, and immunohistochemistry (IHC) were performed, respectively.Results: The entire IBS group (n = 36) exhibited decreased levels of claudin-1 and -2 mRNA compared to the control group (n = 24), with statistical significance (p < 0.05). Additionally, in western blot analyses, both claudin-1 and ZO-1 levels were significantly reduced in the IBS group compared to the control group (n = 24) (p < 0.05). IHC analysis further revealed that ZO-1 expression was significantly lower in the IBS group than in the control group (p < 0.001). This trend of reduced ZO-1 expression was also observed in the moderate-to-severe IBS subgroup (p < 0.001). Significantly, ZO-1 expression was notably lower in both the young- (p = 0.036) and old-aged (p = 0.039) IBS groups compared to their respective age-matched control groups. Subtype analysis indicated a more pronounced decrease in ZO-1 expression with advancing age.Conclusion: ZO-1 expression was especially decreased in the aged IBS group. These results suggest that ZO-1 might be the prominent TJ protein causing IBS in the aging population.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"39 6","pages":"906-916"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142649393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Machine learning approaches toward an understanding of acute kidney injury: current trends and future directions. 了解急性肾损伤的机器学习方法：当前趋势和未来方向。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-29 DOI: 10.3904/kjim.2024.098

Inyong Jeong, Nam-Jun Cho, Se-Jin Ahn, Hwamin Lee, Hyo-Wook Gil

{"title":"Machine learning approaches toward an understanding of acute kidney injury: current trends and future directions.","authors":"Inyong Jeong, Nam-Jun Cho, Se-Jin Ahn, Hwamin Lee, Hyo-Wook Gil","doi":"10.3904/kjim.2024.098","DOIUrl":"10.3904/kjim.2024.098","url":null,"abstract":"Acute kidney injury (AKI) is a significant health challenge associated with adverse patient outcomes and substantial economic burdens. Many authors have sought to prevent and predict AKI. Here, we comprehensively review recent advances in the use of artificial intelligence (AI) to predict AKI, and the associated challenges. Although AI may detect AKI early and predict prognosis, integration of AI-based systems into clinical practice remains challenging. It is difficult to identify AKI patients using retrospective data; information preprocessing and the limitations of existing models pose problems. It is essential to embrace standardized labeling criteria and to form international multi-institutional collaborations that foster high-quality data collection. Additionally, existing constraints on the deployment of evolving AI technologies in real-world healthcare settings and enhancement of the reliabilities of AI outputs are crucial. Such efforts will improve the clinical applicability, performance, and reliability of AKI Clinical Support Systems, ultimately enhancing patient prognoses.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"882-897"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569930/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Impact of discharge checklist on guideline-directed medical therapy and mid-term prognosis in heart failure. 出院清单对指导性医疗治疗和心力衰竭中期预后的影响。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-24 DOI: 10.3904/kjim.2024.088

Won-Seok Lee, Kyu-Sun Lee, Helsi Rismiati, Hae-Young Lee

{"title":"Impact of discharge checklist on guideline-directed medical therapy and mid-term prognosis in heart failure.","authors":"Won-Seok Lee, Kyu-Sun Lee, Helsi Rismiati, Hae-Young Lee","doi":"10.3904/kjim.2024.088","DOIUrl":"10.3904/kjim.2024.088","url":null,"abstract":"Background/aims: Despite the proven benefit of the guideline-directed medical therapy (GDMT), it remains underutilized in patients hospitalized with acute heart failure (HF). We aimed to evaluate the impact of the discharge checklist on GDMT installation and the prognosis of HF patients.Methods: This study was a single-center, observational study that included all patients admitted for HF from March 2021 to February 2023. The data were retrieved from electronic medical records and discharge checklists. A comparison was conducted between the checklist group and the non-checklist group. The primary endpoint was a composite of all-cause mortality or readmission for HF within 6 months.Results: The checklist was completed for 537 patients (checklist group) and not for 187 patients (non-checklist group). The proportion of patients to whom two or more components of GDMT were prescribed was significantly higher in the checklist group than in the non-checklist group (59.6% vs 42.2%, p < 0.001). The checklist group exhibited a significantly lower primary outcome compared to the non-checklist group (27.4% vs. 36.4%, HR 0.73, 95% CI 0.55-0.98, p = 0.036). The effect of the checklist was more prominent in HF with reduced ejection fraction (HR 0.51, 95% CI 0.34-0.77, p = 0.001) than in HF with mildly-reduced and preserved ejection fraction (HR 0.91, 95% CI 0.58-1.42, p = 0.676) (p for interaction = 0.06).Conclusion: The implementation of the discharge checklist was associated with an improvement in GDMT prescription and an improved prognosis in patients with HF with reduced ejection fraction.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"945-956"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569919/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511039","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Prevalence and risk factors for gallstone and renal stone formation in patients with intestinal Behçet's disease. 肠道白塞氏病患者胆石和肾结石形成的发病率和风险因素。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-09-01 Epub Date: 2024-08-13 DOI: 10.3904/kjim.2024.006

Jaewon Song, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jihye Park, Jae Hee Cheon

{"title":"Prevalence and risk factors for gallstone and renal stone formation in patients with intestinal Behçet's disease.","authors":"Jaewon Song, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jihye Park, Jae Hee Cheon","doi":"10.3904/kjim.2024.006","DOIUrl":"10.3904/kjim.2024.006","url":null,"abstract":"Background/aims: The association between inflammatory bowel disease (IBD) and gallstone and renal stone formation has been established. However, few studies have investigated this association in patients with intestinal Behçet's disease (BD). We aimed to examine the prevalence of gallstones and renal stones in patients with intestinal BD and identify potential risk factors.Methods: We analyzed gallstone and renal stone occurrences in 553 patients diagnosed with intestinal BD who had undergone cross-sectional imaging examinations between March 2005 and April 2021 at the IBD Center, Severance Hospital, Seoul, South Korea. Logistic regression models were used to identify risk factors for gallstone and renal stone formation.Results: Of 553 patients over a mean 12.1-year duration, 141 (25.4%) patients had gallstones and 35 (6.3%) had renal stones. In multivariate logistic regression analysis, disease duration > 19 years (OR 2.91, 95% CI 1.56-5.44, 0.002). No significant correlation 0.001), prior intestinal BD-related surgery (OR 2.29, 95% CI 1.42-3.68, p < 0.001), and disease activity index for intestinal BD scores ≥ 75 (OR 2.23, 95% CI 1.12-4.45, p = 0.022) were associated with increased gallstone occurrence. A positive correlation was observed between renal stones, disease duration > 19 years (OR 5.61, 95% CI 1.98-15.90, p = 0.001) and frequent hospitalization (> 3 times) (OR 3.29, 95% CI 1.52-7.13, p = 0.002). No significant correlation was observed between gallstone and renal stone occurrence.Conclusion: These findings contribute to greater understanding concerning gallstone and renal stone prevalence and associated risk factors in patients with intestinal BD.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"770-782"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384251/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972130","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Patterns of hormonal changes in hypophysitis by immune checkpoint inhibitor. 免疫检查点抑制剂对肾上腺皮质功能减退症的荷尔蒙变化模式。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-09-01 Epub Date: 2024-08-30 DOI: 10.3904/kjim.2023.523

Hyunji Sang, Yun Kyung Cho, Sang-Hyeok Go, Hwa Jung Kim, Eun Hee Koh

{"title":"Patterns of hormonal changes in hypophysitis by immune checkpoint inhibitor.","authors":"Hyunji Sang, Yun Kyung Cho, Sang-Hyeok Go, Hwa Jung Kim, Eun Hee Koh","doi":"10.3904/kjim.2023.523","DOIUrl":"10.3904/kjim.2023.523","url":null,"abstract":"Background/aims: Immune checkpoint inhibitors (ICIs) can induce immune-related adverse events, including endocrine dysfunctions, which can have serious consequences on patient health and quality of life. The clinical course and characteristics of immune-related hypophysitis (irH) are not well established. This study aimed to analyze the clinical course and characteristics of irH.Methods: This single-center, retrospective study analyzed data from electronic medical records of Asan Medical Center, spanning January 2017 through June 2021. It included adult patients with solid tumors who underwent thyroid and adrenal function tests, along with gonadotropin and/or growth hormone evaluations, following the initiation of ICI treatment within the same period. The study explored the clinical characteristics of ICI-treated patients with and without irH, the incidence of irH, the time to irH onset, and the associated hormonal changes.Results: Twenty-one patients were included in this analysis. Clinical characteristics did not differ significantly between the irH (n = 13) and non-irH (n = 8) groups. Deficiency rates in the irH group were 23.1% for thyroid-stimulating hormone (n = 3), 76.9% for adrenocorticotropic hormone (n = 10), 61.5% for gonadotropin (n = 8), and 15.4% for growth hormone (n = 2). The overall incidence was 0.9 per person-year, with 6-month and 1-year cumulative incidences of 38.8% and 57.1%, respectively. The median time from ICI initiation to irH diagnosis was 7.7 months. Time to levothyroxine replacement was shorter in the irH group.Conclusion: The findings provide evidence that could facilitate the prediction of ICI-induced irH based on clinical course and characteristics.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"39 5","pages":"801-812"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384252/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

High vegetable consumption and regular exercise are associated with better quality of life in patients with gout. 多吃蔬菜和经常锻炼与痛风患者生活质量的提高有关。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-09-01 Epub Date: 2024-06-24 DOI: 10.3904/kjim.2023.476

Hyunsue Do, Hyo Jin Choi, Byoongyong Choi, Chang-Nam Son, Sang-Hyon Kim, You-Jung Ha, Ji Hyoun Kim, Min Jung Kim, Kichul Shin, Hyun-Ok Kim, Ran Song, Sung Won Lee, Joong Kyong Ahn, Seung-Geun Lee, Chang Hoon Lee, Kyeong Min Son, Ki Won Moon

{"title":"High vegetable consumption and regular exercise are associated with better quality of life in patients with gout.","authors":"Hyunsue Do, Hyo Jin Choi, Byoongyong Choi, Chang-Nam Son, Sang-Hyon Kim, You-Jung Ha, Ji Hyoun Kim, Min Jung Kim, Kichul Shin, Hyun-Ok Kim, Ran Song, Sung Won Lee, Joong Kyong Ahn, Seung-Geun Lee, Chang Hoon Lee, Kyeong Min Son, Ki Won Moon","doi":"10.3904/kjim.2023.476","DOIUrl":"10.3904/kjim.2023.476","url":null,"abstract":"Background/aims: The Gout Impact Scale (GIS), a part of the Gout Assessment Questionnaire 2.0, is used to measure gout-specific health-related quality of life (HRQOL). Although several studies have been conducted on the factors affecting the HRQOL of patients with gout, few have focused on lifestyle factors. This study aimed to investigate the correlation between lifestyle habits and HRQOL using the GIS in patients with gout.Methods: We used data from the Urate-Lowering TheRApy in Gout (ULTRA) registry, a prospective cohort of Korean patients with gout treated at multiple centers nationwide. The patients were aged ≥18 years and met the 2015 American College of Rheumatology/European League Against Rheumatism gout classification criteria. They were asked to complete a GIS and questions regarding their lifestyle habits at enrollment.Results: The study included 232 patients. 'Gout concern overall' scores in the GIS were significantly lower in patients who exercised more frequently and consumed soft drinks and meat less, and 'well-being during attack' scores were significantly lower in patients who consumed vegetables and exercised more frequently. The frequency of vegetable consumption had a negative linear relationship with the 'well-being during attack' and 'gout concern during attack' scores (p = 0.01, p = 0.001, respectively). The frequency of exercise had a negative linear relationship with the 'gout concern overall' and 'gout concern during attack' scores (p = 0.04 and p = 0.002, respectively).Conclusion: Patients with gout who frequently consumed vegetables and exercised regularly experienced less impact of gout, exhibiting a better GIS that represented HRQOL.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"845-854"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384246/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141443597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Gut microbiota dysbiosis and its impact on asthma and other lung diseases: potential therapeutic approaches. 肠道微生物群失调及其对哮喘和其他肺部疾病的影响：潜在的治疗方法。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-09-01 Epub Date: 2024-08-30 DOI: 10.3904/kjim.2023.451

Young-Chan Kim, Kyoung-Hee Sohn, Hye-Ryun Kang

{"title":"Gut microbiota dysbiosis and its impact on asthma and other lung diseases: potential therapeutic approaches.","authors":"Young-Chan Kim, Kyoung-Hee Sohn, Hye-Ryun Kang","doi":"10.3904/kjim.2023.451","DOIUrl":"10.3904/kjim.2023.451","url":null,"abstract":"The emerging field of gut-lung axis research has revealed a complex interplay between the gut microbiota and respiratory health, particularly in asthma. This review comprehensively explored the intricate relationship between these two systems, focusing on their influence on immune responses, inflammation, and the pathogenesis of respiratory diseases. Recent studies have demonstrated that gut microbiota dysbiosis can contribute to asthma onset and exacerbation, prompting investigations into therapeutic strategies to correct this imbalance. Probiotics and prebiotics, known for their ability to modulate gut microbial compositions, were discussed as potential interventions to restore immune homeostasis. The impact of antibiotics and metabolites, including short-chain fatty acids produced by the gut microbiota, on immune regulation was examined. Fecal microbiota transplantation has shown promise in various diseases, but its role in respiratory disorders is not established. Innovative approaches, including mucus transplants, inhaled probiotics, and microencapsulation strategies, have been proposed as novel therapeutic avenues. Despite challenges, including the sophisticated adaptability of microbial communities and the need for mechanistic clarity, the potential for microbiota-based interventions is considerable. Collaboration between researchers, clinicians, and other experts is essential to unravel the complexities of the gut-lung axis, paving a way for innovative strategies that could transform the management of respiratory diseases.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"39 5","pages":"746-758"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142299144","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical effects of non-pharmaceutical interventions for COVID-19 on other nationally notifiable infectious diseases in South Korea. 针对 COVID-19 的非药物干预措施对韩国其他国家通报传染病的临床影响。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-09-01 Epub Date: 2024-08-13 DOI: 10.3904/kjim.2023.501

Hyun-Jin Lee, Beom Seuk Hwang, Seong Ho Im, Seog-Kyun Mun, Munyoung Chang

{"title":"Clinical effects of non-pharmaceutical interventions for COVID-19 on other nationally notifiable infectious diseases in South Korea.","authors":"Hyun-Jin Lee, Beom Seuk Hwang, Seong Ho Im, Seog-Kyun Mun, Munyoung Chang","doi":"10.3904/kjim.2023.501","DOIUrl":"10.3904/kjim.2023.501","url":null,"abstract":"Background/aims: This study aimed to assess the impact of non-pharmaceutical interventions (NPIs) implemented during the COVID-19 pandemic on nationally notifiable infectious diseases (NNIDs) in South Korea.Methods: Long-term data on seven NNIDs from 2018 to 2021 were analyzed to identify trends and change points using a change point detection technique. The timings of the NPI implementations were compared to the identified change points to determine their association.Results: Varicella, mumps, and scarlet fever showed a significant decrease in incidence following the implementation of NPIs during the COVID-19 pandemic. These diseases, which are primarily transmitted through respiratory droplets, demonstrated a clear response to NPIs. However, carbapenem-resistant Enterobacterales (CRE) showed an increasing trend unrelated to the timing of NPI implementation, suggesting the complex nature of controlling healthcare-associated infections. Hepatitis A, hepatitis C, and scrub typhus did not show significant changes associated with NPIs, likely due to their non-respiratory route of transmission.Conclusion: NPIs effectively controlled NNIDs, particularly those transmitted through respiratory infections. However, the impact varied depending on the disease. Understanding the effectiveness and limitations of NPIs is crucial for developing comprehensive public health strategies during infectious disease outbreaks.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"823-832"},"PeriodicalIF":2.2,"publicationDate":"2024-09-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11384254/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141972128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of esophagogastric junctional outlet obstruction caused by thoracic aortic aneurysm. 一例由胸主动脉瘤引起的食管胃交界出口梗阻。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-09-01 Epub Date: 2024-05-22 DOI: 10.3904/kjim.2024.084

Jin Ook Jang, Tae Un Kim, Hwaseong Ryu, Byung-Soo Park, Su Jin Kim

引用次数: 0