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Inequalities in biologics utilization for rheumatoid arthritis according to socioeconomic status. 类风湿关节炎生物制剂使用的不平等与社会经济地位有关。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-07-01 DOI: 10.3904/kjim.2024.207
Oh Chan Kwon, Min-Chan Park
{"title":"Inequalities in biologics utilization for rheumatoid arthritis according to socioeconomic status.","authors":"Oh Chan Kwon, Min-Chan Park","doi":"10.3904/kjim.2024.207","DOIUrl":"10.3904/kjim.2024.207","url":null,"abstract":"","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"39 4","pages":"545-546"},"PeriodicalIF":2.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236807/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical course of asymptomatic duodenal subepithelial lesions. 无症状十二指肠上皮下病变的临床过程。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-07-01 Epub Date: 2024-06-13 DOI: 10.3904/kjim.2023.358
Seokin Kang, Kwangbeom Park, Do Hoon Kim, Yuri Kim, Hee Kyong Na, Jeong Hoon Lee, Ji Yong Ahn, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
{"title":"Clinical course of asymptomatic duodenal subepithelial lesions.","authors":"Seokin Kang, Kwangbeom Park, Do Hoon Kim, Yuri Kim, Hee Kyong Na, Jeong Hoon Lee, Ji Yong Ahn, Kee Wook Jung, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung","doi":"10.3904/kjim.2023.358","DOIUrl":"10.3904/kjim.2023.358","url":null,"abstract":"<p><strong>Background/aims: </strong>There is limited knowledge regarding the management of duodenal subepithelial lesions (SELs) owing to a lack of understanding of their natural course. This study aimed to assess the natural course of asymptomatic duodenal SELs and provide management recommendations.</p><p><strong>Methods: </strong>Patients diagnosed with duodenal SELs and followed up for a minimum of 6 months were retrospectively investigated.</p><p><strong>Results: </strong>Among the 443,533 patients who underwent esophagogastroduodenoscopy between 2008 and 2020, duodenal SELs were identified in 0.39% (1,713 patients). Among them, 396 duodenal SELs were monitored for a median period of 72.5 months (interquartile range, 37.7-111.3 mo). Of them, 16 SELs (4.0%) showed substantial changes in size or morphology at a median follow-up of 35.1 months (interquartile range, 21.7-51.4 mo). Of these SELs with substantial changes, tissues of two SELs were acquired using endoscopic ultrasound-guided fine needle aspiration biopsy: one was a lipoma and the other was non-diagnostic. Three SELs were surgically or endoscopically removed; two were diagnosed as gastrointestinal stromal tumors, and one was a lipoma. An initial size of 20 mm or larger was associated with substantial changes during follow-up (p = 0.016).</p><p><strong>Conclusion: </strong>While the majority of duodenal SELs may not exhibit substantial interval changes, regular follow-up with endoscopy may be necessary for cases with an initial size of 20 mm or larger, considering a possibility of malignancy.</p>","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"603-611"},"PeriodicalIF":2.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236810/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy comparison of high-genetic barrier nucleos(t)ide analogues in treatment-naïve chronic hepatitis B patients: a network meta-analysis. 高遗传屏障核苷（t）ide 类似物对治疗无效的慢性乙型肝炎患者的疗效比较：一项网络荟萃分析。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-07-01 Epub Date: 2024-06-13 DOI: 10.3904/kjim.2023.311
Jaejun Lee, Ahlim Lee, Pil Soo Sung, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Hyun Yang
{"title":"Efficacy comparison of high-genetic barrier nucleos(t)ide analogues in treatment-naïve chronic hepatitis B patients: a network meta-analysis.","authors":"Jaejun Lee, Ahlim Lee, Pil Soo Sung, Jeong Won Jang, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Hyun Yang","doi":"10.3904/kjim.2023.311","DOIUrl":"10.3904/kjim.2023.311","url":null,"abstract":"<p><strong>Background/aims: </strong>Four high-genetic barrier nucleos(t)ide analogues (NAs) for chronic hepatitis B (CHB), namely entecavir (ETV), tenofovir disoproxil fumarate (TDF), tenofovir alafenamide (TAF), and besifovir dipivoxil maleate (BSV), have been established. The aim of this study is to investigate the efficacy of four high-genetic barrier NAs using a network meta-analysis of randomized trials and propensity score-matched cohorts.</p><p><strong>Methods: </strong>Systematic search was performed using PubMed, Cochrane library, and EMBASE and included randomized controlled trials and cohort studies that used propensity score matching. Studies on treatment-naïve CHB patients treated with ETV, TDF, TAF, or BSV were included. Outcomes included alanine aminotransferase normalization and hepatitis B e antigen seroclearance at week 48 and undetectable hepatitis B virus DNA at weeks 48 and 96. Network meta-analysis was performed to synthesize the results.</p><p><strong>Results: </strong>In total, 15,000 patients from 16 studies were included. In terms of 48- and 96-week virologic response (VR), TDF outperformed ETV with statistical significance (48 weeks: odds ratio [OR], 1.38; p < 0.001; 96 weeks: OR, 1.57; p = 0.004). ETV was ranked first for 48-week biochemical response (BR) and outperformed TDF (OR, 0.76; p = 0.028). In the sensitivity analyses, 48-week VR from randomized-controlled trials were compiled, and the same trend toward the superiority of TDF over ETV was found (OR, 1.51; p = 0.030).</p><p><strong>Conclusion: </strong>Four high-genetic barrier NAs were compared, and TDF was more likely to achieve a VR after 48 weeks, while ETV provided a superior BR after 48 weeks.</p>","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"577-589"},"PeriodicalIF":2.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236812/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141312087","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Bilateral leg pain and swelling with abnormal imaging findings in a patient with voriconazole. 一名使用伏立康唑的患者出现双侧腿部疼痛和肿胀，且影像学检查结果异常。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-07-01 Epub Date: 2024-05-27 DOI: 10.3904/kjim.2024.070
Hyeon Mu Jang, Hyeonwoo Kwon, Yunsuk Choi, Sung-Han Kim
{"title":"Bilateral leg pain and swelling with abnormal imaging findings in a patient with voriconazole.","authors":"Hyeon Mu Jang, Hyeonwoo Kwon, Yunsuk Choi, Sung-Han Kim","doi":"10.3904/kjim.2024.070","DOIUrl":"10.3904/kjim.2024.070","url":null,"abstract":"","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"695-696"},"PeriodicalIF":2.2,"publicationDate":"2024-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11236805/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141155856","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Literature review of non-pharmacological treatment for patients with axial spondyloarthritis. 轴性脊柱关节炎患者的非药物治疗文献综述。
IF 2.4 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-05-27 DOI: 10.3904/kjim.2023.485
Jina Yeo, Mi Ryoung Seo, Jun Won Park, Yeon-Ah Lee, Ju Ho Lee, Eun Ha Kang, Seon Mi Ji, Han Joo Baek
{"title":"Literature review of non-pharmacological treatment for patients with axial spondyloarthritis.","authors":"Jina Yeo, Mi Ryoung Seo, Jun Won Park, Yeon-Ah Lee, Ju Ho Lee, Eun Ha Kang, Seon Mi Ji, Han Joo Baek","doi":"10.3904/kjim.2023.485","DOIUrl":"https://doi.org/10.3904/kjim.2023.485","url":null,"abstract":"<p><p>Axial spondyloarthritis (axSpA) is a chronic inflammatory disorder affecting the sacroiliac joints and axial spine. Along with pharmacotherapy, non-pharmacological interventions for axSpA are crucial and constitute the cornerstone of treatment. Here, we review the evidence for non-pharmacological treatment of axSpA as a basis for the 2023 Korean treatment recommendations for patients with axSpA. The effectiveness of the core non-pharmacological approaches, such as education, smoking cessation, and exercise, has been reaffirmed. High-quality research on surgical treatment is limited. However, total hip replacement is advised in patients with ongoing pain or disability and visible structural damage to the hip on imaging. Urgent spinal intervention should be considered in cases of acute spinal pain with neurological deficiency or concurrent unstable fractures. Evidence for complementary therapies, including spas and acupuncture, remains insufficient.</p>","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-05-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141154164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Screening and diagnosis of atrial fibrillation using wearable devices. 使用可穿戴设备筛查和诊断心房颤动。
IF 2.4 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-05-03 DOI: 10.3904/kjim.2023.521
Yoon Jung Park, Myung Hwan Bae
{"title":"Screening and diagnosis of atrial fibrillation using wearable devices.","authors":"Yoon Jung Park, Myung Hwan Bae","doi":"10.3904/kjim.2023.521","DOIUrl":"https://doi.org/10.3904/kjim.2023.521","url":null,"abstract":"<p><p>In recent years, the development and use of various devices for the screening of atrial fibrillation (AF) have significantly increased. Such devices include 12-lead electrocardiogram (ECG), photoplethysmography systems, and single-lead ECG and ECG patches. This review outlines several studies that have focused on the feasibility and efficacy of such devices for AF screening, and summarizes the risks and benefits involved in the initiation of anticoagulant therapy after early detection of AF. We also describe several ongoing trials on unresolved issues associated with AF screening. Overall, this review provides a comprehensive summary of the current state of AF screening and its implications for patient care.</p>","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":2.4,"publicationDate":"2024-05-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140872983","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
An unusual cause of a huge abscess in the thigh. 大腿上有一个巨大的脓肿，原因很不寻常。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-05-01 Epub Date: 2023-11-30 DOI: 10.3904/kjim.2023.305
Dae Gon Ryu, Su Bum Park, Cheol Woong Choi, Su Jin Kim, Hyeong Seok Nam
{"title":"An unusual cause of a huge abscess in the thigh.","authors":"Dae Gon Ryu, Su Bum Park, Cheol Woong Choi, Su Jin Kim, Hyeong Seok Nam","doi":"10.3904/kjim.2023.305","DOIUrl":"10.3904/kjim.2023.305","url":null,"abstract":"","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"537-538"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076892/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A novel strategy for predicting critical illness in hospital-acquired COVID-19. 预测医院感染 COVID-19 危重症的新策略。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-05-01 Epub Date: 2024-04-30 DOI: 10.3904/kjim.2024.127
Woo Hyun Cho
{"title":"A novel strategy for predicting critical illness in hospital-acquired COVID-19.","authors":"Woo Hyun Cho","doi":"10.3904/kjim.2024.127","DOIUrl":"10.3904/kjim.2024.127","url":null,"abstract":"","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"39 3","pages":"371-372"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076901/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877698","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantitative and qualitative evaluation of antimicrobial usage: the first step for antimicrobial stewardship. 抗菌药物使用的定量和定性评估：抗菌药物管理的第一步。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-05-01 Epub Date: 2024-04-30 DOI: 10.3904/kjim.2023.506
Song Mi Moon, Bongyoung Kim, Hong Bin Kim
{"title":"Quantitative and qualitative evaluation of antimicrobial usage: the first step for antimicrobial stewardship.","authors":"Song Mi Moon, Bongyoung Kim, Hong Bin Kim","doi":"10.3904/kjim.2023.506","DOIUrl":"10.3904/kjim.2023.506","url":null,"abstract":"<p><p>The identification of antimicrobial use patterns is essential for determining key targets for antimicrobial stewardship interventions and evaluating the effectiveness thereof. Accurately identifying antimicrobial use patterns requires quantitative evaluation, which focuses on measuring the quantity and frequency of antimicrobial use, and qualitative evaluation, which assesses the appropriateness, effectiveness, and potential side effects of antimicrobial prescriptions. This paper summarizes the quantitative and qualitative methods used to evaluate antimicrobials, drawing insights from overseas and domestic cases.</p>","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"39 3","pages":"383-398"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076899/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Predicting Helicobacter pylori infection from endoscopic features. 从内窥镜特征预测幽门螺旋杆菌感染。
IF 2.2 4区 医学
Korean Journal of Internal Medicine Pub Date : 2024-05-01 Epub Date: 2024-04-30 DOI: 10.3904/kjim.2023.300
Jun-Young Seo, Ji Yong Ahn, Seonok Kim, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung
{"title":"Predicting Helicobacter pylori infection from endoscopic features.","authors":"Jun-Young Seo, Ji Yong Ahn, Seonok Kim, Hee Kyong Na, Jeong Hoon Lee, Kee Wook Jung, Do Hoon Kim, Kee Don Choi, Ho June Song, Gin Hyug Lee, Hwoon-Yong Jung","doi":"10.3904/kjim.2023.300","DOIUrl":"10.3904/kjim.2023.300","url":null,"abstract":"<p><strong>Background: </strong>Helicobacter pylori infection, prevalent in more than half of the global population, is associated with various gastrointestinal diseases, including peptic ulcers and gastric cancer. The effectiveness of early diagnosis and treatment in preventing gastric cancer highlights the need for improved diagnostic methods. This study aimed to develop a simple scoring system based on endoscopic findings to predict H. pylori infection.</p><p><strong>Methods: </strong>A retrospective analysis was conducted on 1,007 patients who underwent upper gastrointestinal endoscopy at Asan Medical Center from January 2019 to December 2021. Exclusion criteria included prior H. pylori treatment, gastric surgery, or gastric malignancies. Diagnostic techniques included rapid urease and 13C-urea breath tests, H. pylori culture, and assessment of endoscopic features following the Kyoto gastritis classification. A new scoring system based on endoscopic findings including regular arrangement of collecting venules (RAC), nodularity, and diffuse or spotty redness was developed for predicting H. pylori infection, utilizing logistic regression analysis in the development set.</p><p><strong>Results: </strong>The scoring system demonstrated high predictive accuracy for H. pylori infection in the validation set. Scores of 2 and 3 were associated with 96% and 99% infection risk, respectively. Additionally, there was a higher prevalence of diffuse redness and sticky mucus in cases where the initial H. pylori eradication treatment failed.</p><p><strong>Conclusion: </strong>Our scoring system showed potential for improving diagnostic accuracy in H. pylori infection. H. pylori testing should be considered upon spotty redness, diffuse redness, nodularity, and RAC absence on endoscopic findings as determined by the predictive scoring system.</p>","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"39 3","pages":"439-447"},"PeriodicalIF":2.2,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11076888/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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