Korean Journal of Internal Medicine最新文献_第6页

Impaired aldosterone response to potassium and hyperkalemia in patients receiving a renin-angiotensin-aldosterone system inhibitor. 接受肾素-血管紧张素-醛固酮系统抑制剂的患者对钾和高钾血症的醛固酮反应受损。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-05-01 Epub Date: 2025-04-30 DOI: 10.3904/kjim.2024.160

Miyeon Kim, Hwa Young Lee, Hyunwoo Kim

{"title":"Impaired aldosterone response to potassium and hyperkalemia in patients receiving a renin-angiotensin-aldosterone system inhibitor.","authors":"Miyeon Kim, Hwa Young Lee, Hyunwoo Kim","doi":"10.3904/kjim.2024.160","DOIUrl":"10.3904/kjim.2024.160","url":null,"abstract":"Background/aims: Angiotensin-converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs) are associated with the development of hyperkalemia. We evaluated the relationship between the serum aldosterone-to-potassium ratio (APR) and the risk of developing hyperkalemia in patients with chronic kidney disease (CKD) receiving ACEIs or ARBs.Methods: One hundred eighty-six patients with stage 3-4 CKD receiving an ACEI or ARB for at least 3 months were evaluated. Serum aldosterone and potassium concentrations were measured simultaneously, and serum APR was calculated (ng/mL per mmol/L). Patients were divided into two groups for comparison according to the median value above or below 2.42. The primary outcome was the difference between the two groups in the development of hyperkalemia (defined as a serum potassium level > 5.5 mmol/L). Incidence rates and risk factors of hyperkalemia were assessed.Results: During the follow-up period, 144 hyperkalemic events in 81 patients (43.5%) were identified, yielding an incidence rate of 24.6 events/100 person-years. The incidence rate was significantly higher in patients with a low serum APR than in patients with a high APR (35.8 events/100 patient-years vs. 12.9 events/100 patient-years, p < 0.001). In addition, diabetes mellitus, history of hyperkalemia, CKD progression during the follow-up period, and low serum APR were predictors of the development of hyperkalemia.Conclusion: Low serum APR was associated with the occurrence of hyperkalemia in patients with CKD receiving ACEIs or ARBs, suggesting that the identification of patients administered these drugs who are at high risk for hyperkalemia may be achieved using this index.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"40 3","pages":"468-481"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081116/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144042186","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Comparison of extrafine and non-extrafine inhaled corticosteroids/long-acting β2-agonists as maintenance and reliever therapy in asthma: a randomized open-label crossover trial. 一项随机、开放标签交叉试验：非吸入和非吸入糖皮质激素/长效β2激动剂作为哮喘维持和缓解治疗的比较

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-05-01 Epub Date: 2025-04-30 DOI: 10.3904/kjim.2024.393

Sang Pyo Lee, Sang Min Lee, Sung-Yoon Kang

{"title":"Comparison of extrafine and non-extrafine inhaled corticosteroids/long-acting β2-agonists as maintenance and reliever therapy in asthma: a randomized open-label crossover trial.","authors":"Sang Pyo Lee, Sang Min Lee, Sung-Yoon Kang","doi":"10.3904/kjim.2024.393","DOIUrl":"10.3904/kjim.2024.393","url":null,"abstract":"Background/aims: Asthma is characterized by chronic inflammation. Inhaled corticosteroids (ICS) remain the cornerstone of anti-inflammatory therapy, targeting both the large and small airways.Methods: This randomized open-label crossover trial included 30 patients receiving step 3 inhaled medication according to the Global Initiative for Asthma (GINA). Patients received beclomethasone/formoterol (BDP/F) for maintenance and reliever therapy for 6 weeks, followed by budesonide/formoterol (BUD/F) for 6 weeks, or vice versa, with a 4-week washout period in between. Assessments at each visit included the Asthma Control Test (ACT), Asthma Control Questionnaire, Quality of Life Questionnaire for Adult Korean Asthmatics, and pulmonary function test. The primary endpoint was the change in forced expiratory flow between 25% and 75% of vital capacity (FEF25-75% pred).Results: Twenty-four patients (15 females, mean age 39.3 years) completed the study. The changes in FEF25-75% pred were comparable between BDP/F and BUD/F (5.79 ± 38.34 vs. -1.36 ± 14.93, p = 0.399). No significant differences were observed between the BDP/F and BUD/F groups in terms of improvement in asthma control or quality of life. However, in the subgroup of patients with positive methacholine bronchial provocation tests, BDP/F significantly improved ACT scores compared to BUD/F (0.92 ± 2.25 vs. -1.31 ± 3.04, p = 0.044).Conclusion: Our study demonstrated that extrafine ICS treatment provided no significant advantage over non-extrafine ICS in improving small airway obstruction or overall asthma control in moderate asthma. This suggests that factors other than particle size may contribute to treatment outcomes.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"40 3","pages":"491-501"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144055174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Herpes zoster infection in patients with inflammatory bowel disease. 炎症性肠病患者的带状疱疹感染。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-05-01 Epub Date: 2025-04-30 DOI: 10.3904/kjim.2024.342

Dong Hyun Kim, Sang-Bum Kang

{"title":"Herpes zoster infection in patients with inflammatory bowel disease.","authors":"Dong Hyun Kim, Sang-Bum Kang","doi":"10.3904/kjim.2024.342","DOIUrl":"10.3904/kjim.2024.342","url":null,"abstract":"Patients with inflammatory bowel disease (IBD) are at increased risk of herpes zoster (HZ), particularly those receiving immunosuppressive treatments such as corticosteroids, thiopurines, and biologics, which elevate the likelihood of varicella-zoster virus reactivation. Despite this, vaccination rates among patients with IBD remain low. Shingrix, a recombinant zoster vaccine, is generally preferred because of its high efficacy (> 90%) and safety profile in immunocompromised individuals, unlike the live attenuated zoster vaccine (Zostavax). This review underscores the importance of HZ vaccination for patients aged ≥ 50 years, as well as for younger patients receiving high-risk therapies such as JAK inhibitors. Tailored vaccination strategies based on individual risk factors, including disease severity, medication use, and ethnicity, may enhance prevention. Given the higher incidence of HZ in certain populations, such as those in Korea, vaccination recommendations should be adapted accordingly. Further research is needed to evaluate the long-term effectiveness of Shingrix in younger patients with IBD to ensure sustained protection and prevent complications, such as postherpetic neuralgia.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"40 3","pages":"347-356"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144051401","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Medical disputes involving lower gastrointestinal endoscopies: cases from the Korean Medical Dispute Mediation and Arbitration Agency. 涉及下消化道内窥镜的医疗纠纷：来自韩国医疗纠纷调解仲裁机构的案例。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-05-01 Epub Date: 2025-04-30 DOI: 10.3904/kjim.2024.343

Eun Hye Oh, Jeong Eun Shin, Jun Yong Bae, Yoon Suk Lee, Yehyun Park, Yong Hwan Kwon, Chang Nyol Paik, Jun Kyu Lee, Tae Hee Lee

{"title":"Medical disputes involving lower gastrointestinal endoscopies: cases from the Korean Medical Dispute Mediation and Arbitration Agency.","authors":"Eun Hye Oh, Jeong Eun Shin, Jun Yong Bae, Yoon Suk Lee, Yehyun Park, Yong Hwan Kwon, Chang Nyol Paik, Jun Kyu Lee, Tae Hee Lee","doi":"10.3904/kjim.2024.343","DOIUrl":"10.3904/kjim.2024.343","url":null,"abstract":"Background/aims: As the number of lower gastrointestinal endoscopies and high-risk examinees increases, the incidence of adverse events associated with these endoscopies has also increased. Medical disputes and lawsuits related to adverse events are rapidly increasing.Methods: Medical disputes related to lower gastrointestinal endoscopy that had been filed in Korean Medical Dispute Mediation and Arbitration Agency (K-medi) from April 2012 to August 2020 were evaluated with the corresponding medical records and written appraisal. Facilities, patients, procedures, adverse events, and outcome-related variables related to medical disputes were analyzed.Results: As the number of lower gastrointestinal endoscopies in Korea increases each year, the number of medical disputes related to lower gastrointestinal endoscopy appraised by K-medi has also increased yearly during the same period. Among the 121 cases analyzed, 86 (71.1%) were conciliated and 35 (28.9%) were cosigned by prosecution. Perforations accounted for the largest proportion of cases (93 cases, 76.9%). Most patients (n = 119, 98.3%) underwent non-emergent procedures, and only 10 (8.3%) underwent them for therapeutic purposes. Approximately one-fifth of the patients (n = 25, 20.7%) died.Conclusion: The number of medical disputes related to lower gastrointestinal endoscopy are increasing. To prevent this, it is important to review the data on existing cases and establish specific response guidelines.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"40 3","pages":"404-426"},"PeriodicalIF":2.2,"publicationDate":"2025-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12081107/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144047793","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex differences in diagnosis and treatment of heart failure: toward precision medicine. 心力衰竭诊断和治疗的性别差异：走向精准医学。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-03-01 DOI: 10.3904/kjim.2024.338

Soo Yong Lee, Seong-Mi Park

{"title":"Sex differences in diagnosis and treatment of heart failure: toward precision medicine.","authors":"Soo Yong Lee, Seong-Mi Park","doi":"10.3904/kjim.2024.338","DOIUrl":"10.3904/kjim.2024.338","url":null,"abstract":"There are sex-related differences in the pathophysiology and phenotype of heart failure (HF) as well as the pharmacokinetics and pharmacodynamics of drugs between women and men due to biological differences, such as heart and vessel size, response to blood volume and pressure, body water and muscle compositions, and dominant sex hormones. Therefore, target drug doses required to achieve the same clinical effect differ between the sexes, while there may also be sex-related differences in side effects of a given drug at the same dose. These biological differences have been reflected in the results of clinical trials. Moreover, women have been underrepresented in pharmacological therapy trials as well as having lower device implantation rates than men. Therefore, the currently recommended target doses of medications based on clinical trials may not be appropriate for women. Although guidelines for HF have been standardized since the last major revision in 2021, most do not differentiate by sex. This review focuses on evidence regarding sex-related differences in multiple aspects of HF, including epidemiology, pathophysiology, clinical features, treatment, and prognosis, highlighting the need for sex-specific treatment guidelines.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"40 2","pages":"196-207"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938682/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Role of endoscopic ultrasound in the diagnosis and local ablative therapy of pancreatic neuroendocrine tumors. 内窥镜超声在胰腺神经内分泌肿瘤的诊断和局部消融治疗中的作用。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-03-01 Epub Date: 2025-02-25 DOI: 10.3904/kjim.2024.293

Yun Je Song, Jun Kyeong Lim, Jun-Ho Choi

引用次数: 0

Fatty liver index and development of lung cancer: a nationwide cohort study. 脂肪肝指数与肺癌发病：一项全国性队列研究。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-03-01 Epub Date: 2024-10-22 DOI: 10.3904/kjim.2024.232

Jihye Lim, Bongseong Kim, Kyungdo Han, Jeong Uk Lim

{"title":"Fatty liver index and development of lung cancer: a nationwide cohort study.","authors":"Jihye Lim, Bongseong Kim, Kyungdo Han, Jeong Uk Lim","doi":"10.3904/kjim.2024.232","DOIUrl":"10.3904/kjim.2024.232","url":null,"abstract":"Background/aims: This study aimed to evaluate the impact of steatotic liver disease severity on the cumulative incidence of lung cancer utilizing data from the Korea National Health Insurance Service (NHIS).Methods: This study examined the risk of lung cancer in the general population in conjunction with the incidence of steatotic liver disease. The study population consisted of 3,261,438 individuals aged 20 years or older who underwent a general health examination in 2009.Results: Individuals with fatty liver index (FLI) of 30-59 exhibited a 1.08-fold increased risk of lung cancer (95% CI: 1.04-1.11), while FLI ≥ 60 was associated with a 1.22-fold elevated risk of lung cancer (95% CI: 1.17-1.28) compared to those with FLI < 30. The risk varied with smoking status; in current smokers, the adjusted HR for the FLI 30-59 group was 1.05 (95% CI: 1.00-1.10), while that in the FLI ≥ 60 group was 1.11 (95% CI: 1.04-1.18). In never- or past-smokers, the adjusted HR for the FLI 30-59 group was 1.10, and that for the FLI ≥ 60 group was 1.31. Subgroup analysis revealed an incidence rate of 1.06 per 1,000 person-years in the consistently high FLI group compared to 1.15 in those with improved FLI. Improving FLI over time was associated with a 0.93-fold decrease in lung cancer risk.Conclusion: Our study demonstrated a correlational relationship between lung cancer incidence and the severity of steatotic liver disease as measured by FLI.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"275-285"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938715/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Initial and peak serum levels of Krebs von den Lungen-6 for predicting the prognosis of patients with COVID-19. 血清克雷布斯·冯·登·伦根-6初始和峰值水平对COVID-19患者预后的预测

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.3904/kjim.2024.161

Geonui Kim, Hyeonwoo Kwon, Sang Hyun Ra, Euijin Chang, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Sung-Han Kim

{"title":"Initial and peak serum levels of Krebs von den Lungen-6 for predicting the prognosis of patients with COVID-19.","authors":"Geonui Kim, Hyeonwoo Kwon, Sang Hyun Ra, Euijin Chang, Seongman Bae, Jiwon Jung, Min Jae Kim, Yong Pil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Sung-Han Kim","doi":"10.3904/kjim.2024.161","DOIUrl":"10.3904/kjim.2024.161","url":null,"abstract":"Background/aims: Krebs von den Lungen-6 (KL-6) is associated with prognosis in patients with COVID-19. However, there is limited data on the correlation between the prognosis of COVID-19 and varying KL-6 levels at different time points. We investigated the optimal cutoff values of the initial and peak serum KL-6 levels to predict mortality and evaluated their correlation with mortality.Methods: This retrospective cohort study collected data on serially collected serum KL-6 levels in patients hospitalized with COVID-19 between October 2020 and January 2022 at a single tertiary hospital in South Korea. The area under the receiver operating characteristic curve and Youden index were used to determine the cutoff points for the initial and peak KL-6 levels that best predicted 30-day mortality. The association between the initial and peak KL-6 values was assessed by univariate and multivariate logistic regression models.Results: A total of 349 patients were included in this study. The mean initial and peak KL-6 levels were significantly higher in the non-survivor group than in the survivor group. The initial and peak KL-6 values that best predicted 30-day mortality were 491.85 U/mL and 660.05 U/mL, respectively. An initial KL-6 level greater than 491.85 U/mL and a peak KL-6 level greater than 660.05 U/mL were significantly associated with 30-day mortality.Conclusion: The initial and peak levels of KL-6 were significantly associated with 30-day mortality in hospitalized patients with COVID-19. These findings suggest that serially monitoring blood KL-6 levels could be a valuable prognostic indicator for COVID-19.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"321-329"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938661/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143483786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Clinical outcomes of esophageal squamous cell carcinoma in patients aged over 80 years. 80岁以上患者食管鳞状细胞癌的临床结果分析。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-03-01 Epub Date: 2025-02-21 DOI: 10.3904/kjim.2024.201

Dae Gon Ryu, Cheol Woong Choi, Su Jin Kim, Su Bum Park, Jin Ook Jang, Bong Soo Son

{"title":"Clinical outcomes of esophageal squamous cell carcinoma in patients aged over 80 years.","authors":"Dae Gon Ryu, Cheol Woong Choi, Su Jin Kim, Su Bum Park, Jin Ook Jang, Bong Soo Son","doi":"10.3904/kjim.2024.201","DOIUrl":"10.3904/kjim.2024.201","url":null,"abstract":"Background/aims: The clinical outcomes and optimal treatment of esophageal squamous cell carcinoma (ESCC) in elderly patients are unclear. This study aimed to assess the clinical outcomes of ESCC in patients aged ≥ 80 years.Methods: Medical records of patients diagnosed with ESCC between December 2008 and February 2024 were retrospectively reviewed. In total, 479 patients with ESCC were included and divided into the elderly (n = 52) and younger (n = 427) groups based on age. The clinical outcomes and survival rates, according to treatment, were compared between the two groups.Results: The median ages of the two groups were 82 years (range, 80-95 yr) and 66 years (41-79 yr). The overall survival was slightly lower in the elderly group; however, no statistical significance (hazard ratio [HR] 1.27, 95% confidence interval [CI] 0.85-1.91; p = 0.238) was observed. No differences were observed in the outcomes or survival between the two groups according to the treatment method (surgery, chemoradiotherapy or radiotherapy alone, and endoscopic resection). The elderly group was more likely to receive no treatment for cancer (30.8% vs. 13.6%, p = 0.002) than the younger group. However, when there was no treatment for cancer in the elderly group, survival was significantly lower than when treatment was administered (HR 0.08, 95% CI 0.03-020; p < 0.001).Conclusion: In patients with ESCC aged ≥ 80 years, active cancer treatment was beneficial, and the results did not differ from those of younger patients.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"230-242"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938664/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143484486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome: a comparative study of 2018-2019 and 2020-2021. 2019冠状病毒病疫情对代谢综合征发病率的性别特异性影响：2018-2019年和2020-2021年的比较研究

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2025-03-01 DOI: 10.3904/kjim.2024.288

Kyeong-Hyeon Chun, Hyun-Jin Kim, Dae Ryong Kang, Jang Young Kim, Wonjin Kim, Yong Whi Jeong, Seung Hwan Han, Kwang Kon Koh

{"title":"Sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome: a comparative study of 2018-2019 and 2020-2021.","authors":"Kyeong-Hyeon Chun, Hyun-Jin Kim, Dae Ryong Kang, Jang Young Kim, Wonjin Kim, Yong Whi Jeong, Seung Hwan Han, Kwang Kon Koh","doi":"10.3904/kjim.2024.288","DOIUrl":"10.3904/kjim.2024.288","url":null,"abstract":"Background/aims: The coronavirus disease 2019 (COVID-19) pandemic has significantly impacted global health, exacerbated metabolic health issues, and altered lifestyle behaviors. This study examined the sex-specific impact of the COVID-19 outbreak on the incidence of metabolic syndrome using data from the Korea National Health and Nutrition Examination Survey (KNHANES).Methods: Data from the KNHANES VII (2018) and VIII (2019-2021), including 15,499 participants, were analyzed. The study population was stratified by sex, and further subdivisions were conducted based on the timeframe relative to the COVID-19 outbreak. Variables such as age, education level, household income, smoking status, and high-risk drinking were analyzed to assess their influence on the prevalence of metabolic syndrome.Results: The overall prevalence of metabolic syndrome significantly increased from 28.11% before the outbreak to 29.69% after the outbreak. Both males and females reported significant increases in waist circumference and fasting glucose levels. Age and education level differentially influenced the prevalence of metabolic syndrome between the sex. Smoking was significantly associated with increased prevalence in males, whereas high-risk drinking was associated with increased prevalence in males and decreased prevalence in females.Conclusion: The COVID-19 pandemic has significantly increased the prevalence of metabolic syndrome with notable sex-specific differences. These findings highlight the need for sex-specific public health interventions to mitigate the impact of the pandemic on metabolic health.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":"40 2","pages":"262-274"},"PeriodicalIF":2.2,"publicationDate":"2025-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11938662/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659258","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0