Korean Journal of Internal Medicine最新文献

Characteristics and outcomes of portal vein thrombosis in patients with inflammatory bowel disease in Korea.

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-12-23 DOI: 10.3904/kjim.2024.181

Ki Jin Kim, Su-Bin Song, Jung-Bin Park, June Hwa Bae, Ji Eun Baek, Ga Hee Kim, Min-Jun Kim, Seung Wook Hong, Sung Wook Hwang, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Chang Sik Yu, Yong-Sik Yoon, Jong-Lyul Lee, Min Hyun Kim, Ho-Su Lee, Sang Hyoung Park

{"title":"Characteristics and outcomes of portal vein thrombosis in patients with inflammatory bowel disease in Korea.","authors":"Ki Jin Kim, Su-Bin Song, Jung-Bin Park, June Hwa Bae, Ji Eun Baek, Ga Hee Kim, Min-Jun Kim, Seung Wook Hong, Sung Wook Hwang, Dong-Hoon Yang, Byong Duk Ye, Jeong-Sik Byeon, Seung-Jae Myung, Suk-Kyun Yang, Chang Sik Yu, Yong-Sik Yoon, Jong-Lyul Lee, Min Hyun Kim, Ho-Su Lee, Sang Hyoung Park","doi":"10.3904/kjim.2024.181","DOIUrl":"https://doi.org/10.3904/kjim.2024.181","url":null,"abstract":"Background/aims: Portal vein thrombosis (PVT) frequently occurs in patients with inflammatory bowel disease (IBD), particularly when influenced by factors such as abdominal infections, IBD flare-ups, or surgical procedures. The implications of PVT range from immediate issues such as intestinal ischemia to long-term concerns including portal hypertension and its complications. However, there is a notable gap in comprehensive studies on PVT in IBD, especially with the increasing incidence of IBD in Asia. This research aimed to evaluate the clinical features and outcomes of PVT in patients with IBD at a leading hospital in South Korea.Methods: This retrospective analysis reviewed adult patients diagnosed with both IBD and PVT from 1989 to 2021 at a renowned South Korean medical center. The study focused on patient characteristics, specifics of PVT, administered treatments, and outcomes, all confirmed through enhanced CT scans.Results: A total of 78 patients met the study's criteria. Notably, only 20.5% (16/78) were treated with oral anticoagulants; however, a vast majority (96.2%; 75/78) achieved complete radiographic resolution (CRR). When comparing patients receiving anticoagulants to those who did not, a significant preference for anticoagulant use was observed in cases where the main portal vein was affected, as opposed to just the left or right veins (p = 0.006). However, multivariable analysis indicated that neither anticoagulant use nor previous surgeries significantly impacted CRR.Conclusions: Patients with IBD and PVT generally had favorable outcomes, regardless of anticoagulant use.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":""},"PeriodicalIF":2.2,"publicationDate":"2024-12-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142878393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Growing chronic consolidative lesion with an air bronchogram. 生长中的慢性合并病灶，伴有气管造影。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-12-18 DOI: 10.3904/kjim.2024.167

Jae Seok Jeong, Chan Yang Cho, Jun Hyung Park, Kum Ju Chae, Yong Chul Lee

引用次数: 0

Femoral veno-arterial extracorporeal membrane oxygenation with a novel biatrial cannula for venous drainage and left ventricular venting. 使用新型双心房插管进行股静脉-动脉体外膜肺氧合，以实现静脉引流和左心室通气。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-12-18 DOI: 10.3904/kjim.2024.046

Jun Hwan Cho, Woosik Han, Eun Jeong Cho, Sang-Yeub Lee, Sang-Wook Kim

引用次数: 0

Kidney replacement therapy trends in end-stage kidney disease patients in South Korea during the COVID-19 pandemic. COVID-19 大流行期间韩国终末期肾病患者的肾脏替代疗法趋势。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-24 DOI: 10.3904/kjim.2024.052

Ah-Young Kim, Min-Jeong Lee, Heejung Choi, Hankil Lee, Inwhee Park

{"title":"Kidney replacement therapy trends in end-stage kidney disease patients in South Korea during the COVID-19 pandemic.","authors":"Ah-Young Kim, Min-Jeong Lee, Heejung Choi, Hankil Lee, Inwhee Park","doi":"10.3904/kjim.2024.052","DOIUrl":"10.3904/kjim.2024.052","url":null,"abstract":"Background/aims: The corona virus disease 2019 posed a major risk for end-stage kidney disease (ESKD) cases. Our study aimed to assess changes in kidney replacement therapy (KRT) trends and healthcare access for these patients during the pandemic.Methods: We retrospectively analyzed nationwide data from July 2017 to June 2022 to assess changes in KRT and ESKD incidence. KRT modalities included peritoneal dialysis (PD), hemodialysis (HD), and kidney transplantation (KT). We utilized the interrupted time series (ITS) method to compare changes in KRT modality before and after the incidence of the COVID-19 pandemic.Results: ESKD incidence remained stable from 2018 to April 2022. The ITS analysis confirmed that the pandemic did not significant impact overall KRT incidence. PD cases decreased (5.7% to 1.3%), while HD cases increased (81.6% to 85%), and KT recipient remained relatively stable (12.7% to 17.3%). The hospitalization and hospital stay decreased in nursing hospital (165.01 days to 147.77 days) and general hospital (61.34 days to 55.58 days) during the pandemic, however, remained unchanged for PD and KT.Conclusion: Our findings indicate no significant changes in ESKD incidence in South Korea during the pandemic. However, there were shifts in modality distribution, with decreased PD and increased HD cases. Notably, HD cases showed a significant reduction in hospital admissions and length of stay. The healthcare system demonstrated stability during the pandemic, with minimal disruptions in ESKD care.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"967-978"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Systemic venous air embolism after percutaneous lung biopsy. 经皮肺活检后的全身静脉空气栓塞。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-08-13 DOI: 10.3904/kjim.2024.114

Min Kyung Jung, Shin Young Kim, Jeong Min Ko

引用次数: 0

Kidney transplantation in the elderly. 老年人的肾移植

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-24 DOI: 10.3904/kjim.2024.089

Byung Hwa Park, Song Yi Kil, Ye Na Kim, Ho Sik Shin, Yeonsoon Jung, Hark Rim

引用次数: 0

Effective control of a severely progressive recurrent respiratory papillomatosis with repetitive cryotherapy. 重复冷冻疗法有效控制了严重进展性复发性呼吸道乳头状瘤病。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-22 DOI: 10.3904/kjim.2024.166

Jae Seok Jeong, Jee Hee Lee, Jun Hyung Park, Yeong Hun Choe, Yong Chul Lee

引用次数: 0

Assessment of small fiber neuropathy and distal sensory neuropathy in female patients with fibromyalgia. 评估纤维肌痛女性患者的小纤维神经病变和远端感觉神经病变。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-29 DOI: 10.3904/kjim.2024.038

Hong Ki Min, Sun Im, Geun-Young Park, Su-Jin Moon

{"title":"Assessment of small fiber neuropathy and distal sensory neuropathy in female patients with fibromyalgia.","authors":"Hong Ki Min, Sun Im, Geun-Young Park, Su-Jin Moon","doi":"10.3904/kjim.2024.038","DOIUrl":"10.3904/kjim.2024.038","url":null,"abstract":"Background/aims: We investigated sudomotor dysfunction, small fiber neuropathy (SFN), and their clinical significance in female fibromyalgia patients.Methods: Fibromyalgia patients and healthy controls (HCs) were recruited. Clinical and laboratory data were measured. Electrochemical skin conductance (ESC) values of hands and feet were assessed by SUDOSCAN. Additionally, several other methods were employed, including nerve conduction study (NCS), electromyography (EMG), and questionnaires. Spearman correlation coefficient was calculated to identify factors associated with ESC values of SUDOSCAN.Results: Twenty-two female fibromyalgia patients and 22 female HCs were recruited. The fibromyalgia group had lower EQ5D and higher Toronto Clinical Neuropathy scores than the HC group. Most of the EMG/NCS findings of motor and proximal sensory nerves were comparable between the fibromyalgia and HC groups, whereas sensory nerve action potential amplitudes of distal sensory nerves were significantly lower in the fibromyalgia group. Mean ESC values of hands and feet were significantly lower in the fibromyalgia group than in the HC group (57.6 ± 16.2 vs. 68.8 ± 10.3 μS, p = 0.010 for hands, 64.9 ± 11.5 vs. 72.0 ± 8.2 μS, p = 0.025 for feet, respectively). Moderate to severe SFN was more common in the fibromyalgia group (68.2%) than in the HC group (68.2 vs. 50%, p = 0.019). Fibromyalgia disease duration was significantly correlated with the ESC values of hands/feet, and tricyclic antidepressant (TCA) responders had higher ESC values than non-responders.Conclusion: SFN was commonly detected in fibromyalgia patients who had normal EMG/NCS findings and was more severe in fibromyalgia patients with longer disease duration. SUDOSCAN may predict response to TCA therapy.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"989-1000"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569927/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142523436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Evolving epidemiology of non-alcoholic fatty liver disease in South Korea: incidence, prevalence, progression, and healthcare implications from 2010 to 2022. 韩国非酒精性脂肪肝流行病学的演变：2010 年至 2022 年的发病率、患病率、进展和对医疗保健的影响。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-24 DOI: 10.3904/kjim.2024.164

Jae Woo Park, Jeong-Ju Yoo, Dong Hyeon Lee, Young Chang, Hoongil Jo, Young Youn Cho, Sangheun Lee, Log Young Kim, Jae Young Jang

{"title":"Evolving epidemiology of non-alcoholic fatty liver disease in South Korea: incidence, prevalence, progression, and healthcare implications from 2010 to 2022.","authors":"Jae Woo Park, Jeong-Ju Yoo, Dong Hyeon Lee, Young Chang, Hoongil Jo, Young Youn Cho, Sangheun Lee, Log Young Kim, Jae Young Jang","doi":"10.3904/kjim.2024.164","DOIUrl":"10.3904/kjim.2024.164","url":null,"abstract":"Background/aims: Non-alcoholic fatty liver disease (NAFLD), now the most common chronic liver worldwide, has become a significant public health concern. This study aims to analyze the evolving epidemiology of NAFLD in South Korea.Methods: We utilized claim data from the Korean National Health Insurance Service from 2010 to 2022 to analyze NAFLD's incidence, prevalence, and progression.Results: From 2010 to 2022, the incidence and prevalence rates of NAFLD each increased from 1.87% to 4.47% and from 10.49% to 17.13%, respectively. The differences in prevalence rates between urban and rural areas were minimal in 2012 and 2022, yet both areas showed significant increases in the prevalence of NAFLD over the decade. The NAFLD group had a higher prevalence of comorbidities compared to the control group, and the most common comorbid condition was hypertension. Moreover, the ten-year incidence rates of malignancy, heart disease, and stroke in the NAFLD group were 13.42%, 15.72%, and 8.36%, respectively, which were significantly higher than those in the control group. The incidence rates of cirrhosis and hepatocellular carcinoma in NAFLD over 10 years were 2.22% and 0.77%, respectively. The total medical costs of NAFLD patients more than doubled over ten years and were all significantly higher than those of the control group.Conclusion: A significant increase in NAFLD prevalence and its impact on healthcare utilization was observed in South Korea. With NAFLD leading to serious liver diseases and increased healthcare costs, integrated care strategies that include both medical treatment and lifestyle modifications are essential.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"931-944"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569921/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142511038","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Steps to understanding diabetes kidney disease: a focus on metabolomics. 了解糖尿病肾病的步骤：聚焦代谢组学。

IF 2.2 4区医学

Korean Journal of Internal Medicine Pub Date : 2024-11-01 Epub Date: 2024-10-22 DOI: 10.3904/kjim.2024.111

Hyo Jin Kim, Sang Heon Song

{"title":"Steps to understanding diabetes kidney disease: a focus on metabolomics.","authors":"Hyo Jin Kim, Sang Heon Song","doi":"10.3904/kjim.2024.111","DOIUrl":"10.3904/kjim.2024.111","url":null,"abstract":"Diabetic nephropathy (DN), a leading cause of chronic kidney disease and end-stage kidney disease (ESKD), poses global health challenges given its increasing prevalence. DN increases the risk of mortality and cardiovascular events. Early identification and appropriate DN management are crucial. However, current diagnostic methods rely on general traditional markers, highlighting the need for DN-specific diagnostics. Metabolomics, the study of small molecules produced by metabolic activity, promises to identify specific biomarkers that distinguish DN from other kidney diseases, decode the underlying disease mechanisms, and predict the disease course. Profound changes in metabolic pathways are apparent in individuals with DN, alterations in the tricarboxylic acid cycle and amino acid and lipid metabolism, suggestive of mitochondrial dysfunction. Metabolomics aids prediction of chronic kidney disease progression; several metabolites serve as indicators of renal functional decline and the risk of ESKD. Integration of such information with other omics data will further enhance our understanding of DN, paving the way to personalized treatment. In summary, metabolomics and multi-omics offer valuable insights into DN and are promising diagnostic and prognostic tools.","PeriodicalId":48785,"journal":{"name":"Korean Journal of Internal Medicine","volume":" ","pages":"898-905"},"PeriodicalIF":2.2,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11569920/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142478332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0