Biodegradation最新文献

{"title":"Ability of mixed fungal cultures to remove glyphosate from soil microcosms under stressful conditions","authors":"Melisa Eglé Aluffi,&nbsp;Karen Magnoli,&nbsp;Cecilia Soledad Carranza,&nbsp;Virginia Carolina Aparicio,&nbsp;Carla Lorena Barberis,&nbsp;Carina Elizabeth Magnoli","doi":"10.1007/s10532-025-10126-4","DOIUrl":"10.1007/s10532-025-10126-4","url":null,"abstract":"<div><p>Many herbicides used extensively to manage weeds and protect economically important crops contain glyphosate (GP) as their main ingredient, which contaminates ecosystems when it spreads from the soil into the surrounding environment. This study evaluated the ability of two fungal strains to remove GP at a microcosm scale. The strains, <i>Aspergillus oryzae</i> AM2 and <i>Mucor circinelloides</i> 166, were tested on their own and in mixed cultures. The microcosms were conditioned at 30 or 70% field capacity (FC), and contaminated with 5000 or 15,000 mg kg⁻¹ GP. The native microbial communities played a crucial role in the dissipation of the herbicide. At the end of the incubation (60 days), they had achieved removal percentages above 95% in most treatments. The exceptions were the microcosms subjected to hydric stress (30% FC) and contaminated with 15,000 mg kg⁻¹ GP, in which the co-cultures outperformed the native microbial species (≥ 80 vs 33% removal, respectively). An increase in AMPA (aminomethylphosphonic acid), the main metabolite of GP degradation, was usually detected after 60 days, which indicates that biodegradation may have been one of the main mechanisms involved in the removal of the herbicide. These results provide information about the potential of two mixed fungal cultures (containing species that are native to agricultural soils) to remove GP under stressful conditions.</p></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 3","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143840500","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Sustainable bioremediation and reuse of heavy metal-contaminated dredged sediments using Bacillus subtilis","authors":"Kalyani Kulkarni,&nbsp;Nehal Jain,&nbsp;G. L. Sivakumar Babu","doi":"10.1007/s10532-025-10127-3","DOIUrl":"10.1007/s10532-025-10127-3","url":null,"abstract":"<div><p>Urbanization has led to heavy metal contamination of dredged sediments, posing severe environmental and health risks. This study investigated the efficacy of <i>Bacillus subtilis</i>-bioremediation and reuse Heavy Metal contaminated sediment as construction material. Recognizing the limitations of conventional calcium chloride, alternative calcium sources for enhanced remediation were explored. The results demonstrate that utilizing calcium hydroxide (0.625 M) as a cementing reagent resulted in optimal compressive strength while minimizing heavy metal leaching. A substantial reduction in leachability: 97.8% for cadmium, 92% for nickel, and 98% for zinc, was observed as determined by USEPA Method 1311. Sequential extraction procedure analysis revealed the effective immobilization of heavy metals within the sediment matrix, primarily through their conversion to metal carbonates and their association with organic matter. This eco-friendly bioremediation approach, combining bacterial activity with sustainable cement stabilization, presents a promising remediation strategy for contaminated dredged sediments, enabling the safe reuse in engineering applications.</p></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 3","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143840357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Inferences made from mineral elements characterisation of anaerobic digestion substrates: preliminary results from avocado oil processing byproducts","authors":"Charles Rashama,&nbsp;Grace N. Ijoma,&nbsp;Tonderayi S. Matambo,&nbsp;Christian Riann","doi":"10.1007/s10532-025-10125-5","DOIUrl":"10.1007/s10532-025-10125-5","url":null,"abstract":"<div><p>The mineral element levels in avocado oil processing byproducts were evaluated to make inferences about these byproducts’ biodegradability behaviour. The mineral assays were determined using ICP-OES methods. Literature was also reviewed to understand how different mineral elements detected in substrates could impact biogas production under anaerobic digestion (AD) conditions. It was noted that there is no consensus among scholars on absolute mineral requirement levels for optimal digester performance since digesters use different substrates operating under varying conditions in most cases. When mineral elements are below certain values, the digester operates sub-optimally. When certain mineral levels are exceeded in digesters, the minerals become toxic to the AD microorganisms and destabilise the biogas digester. Only Zn levels across all avocado oil processing byproducts and K levels in cold-pressed decanter wastewater (CDW) exceeded the toxic level limits pegged at 1 mg/L and 3000 mg/L respectively. These may therefore need corrective action to avoid potential inhibition of the AD process. Mineral assays that seemed adequate and required no supplementation or detoxification were K, P, Fe, Cu, Se and Cr across the studied byproducts. All the other elements (excluding the Hg, As and Cd which are toxic) may require supplementation for optimal digester performances when using avocado oil processing byproducts as biogas digester substrates. However, these inferences may be affected by issues of mineral bioavailability which is a substrate-dependent phenomenon. Mercury cadmium and arsenic are naturally toxic to microorganisms and must be removed or detoxified if detected in substrates. The current study indicates the significance of mineral elements’ characterisation in explaining and potentially guiding the optimisation of substrate biodegradation to biogas.</p></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s10532-025-10125-5.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143809322","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Biodegradable polymer films incorporating phycocyanin and polyhydroxybutyrate: advancing sustainable packaging technologies","authors":"Alireza Farrokheh,&nbsp;Zahed Ahmadi","doi":"10.1007/s10532-025-10123-7","DOIUrl":"10.1007/s10532-025-10123-7","url":null,"abstract":"<div><p>The biocompatibility and degradability of poly hydroxybutyrate (PHB) make it an important material for food packaging. Poly hydroxybutyrate (PHB) is less flexible than typical polymers and more brittle due to its strong crystalline structure and low melting temperature. Furthermore, while poly hydroxybutyrate (PHB) does not have antibiotic capabilities, the inclusion of additional materials such as phycocyanin can boost its antibiotic and antifungal effects. This research focuses on increasing the yield of phycocyanin from the microalgae Spirulina and selecting an optimal green extraction method, and on the other hand, on the synthesis of biodegradable polymers derived from poly hydroxybutyrate in combination with phycocyanin for food packaging applications. This study shows that higher wavelengths of light, an optimal temperature of about 33 degrees Celsius, pH adjustments using changing the composition of the culture medium by increasing metal compounds and using non-invasive, green and inexpensive extraction methods significantly increase biomass production and phycocyanin yield, which in previous research only one to two of the above parameters were considered for protein extraction, which this study has addressed more comprehensively. Also, the synthesis of biodegradable polymers with special properties for packaging applications, including green polymer poly hydroxybutyrate, phycocyanin and beeswax, which has not been done in previous research on modifying the properties of poly hydroxybutyrate using these two research materials, so that with 60% phycocyanin in combination with poly hydroxybutyrate, they show promising properties for food packaging applications. By examining the physical and chemical properties, thermal strength and degradability of the polymer compared to pure poly hydroxybutyrate, it shows further improvement in addition to antibiotic and antifungal properties.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143778147","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comparative study using response surface methodology and artificial neural network for modeling the bio-reduction of hexavalent chromium (Cr⁶⁺) by immobilized cells of Paenibacillus taichungensis strain MAHA in an alginate-gellan gum matrix","authors":"Maha Obaid Al-Osaimi,&nbsp;Mohd Izuan Effendi Halmi,&nbsp;Siti Salwa Abd Gani,&nbsp;Khairil Mahmud,&nbsp;Mohd Yunus Abd Shukor","doi":"10.1007/s10532-025-10124-6","DOIUrl":"10.1007/s10532-025-10124-6","url":null,"abstract":"<div><p>Chromium (Cr⁶⁺) waste poses a hazard as it leads to imbalanced ecosystems and severe health issues. Although, it is widely associated with many industries. Chromium (Cr⁶⁺) reduction by the immobilized cells of <i>Paenibacillus taitungensis</i> strain MAHA-MIE was optimized using response surface methodology (RSM) and artificial neural networks (ANN). The RSM-Box-Behnken Design (BBD) was selected to investigate the effects of chromium (Cr⁶⁺) concentration, alginate concentration, gellan gum concentration, bead size, and the number of beads on chromium (Cr⁶⁺) reduction rate. Experimental data from the BBD was used to train a feed-forward, multilayer artificial neural network (ANN). Results show that the ANN model outperformed the response surface methodology (RSM) based on actual and predicted data, with lower errors and a higher R² value. The ANN model predicted the optimum points as follows: 155 ppm chromium (Cr⁶⁺), 0.32% alginate, 0.65% gellan gum, 0.5 cm beads, and 27 beads. The validation confirmed a high agreement of chromium (Cr⁶⁺) reduction rate between the validation value (99.00%) and the predicted value (99.99%), with the lowest deviation at 0.1%. Modeling abilities were compared using statistical criteria, including Root Mean Square Error (RMSE), Standard Error of Prediction (SEP), Relative Percent Deviation (RPD), and regression coefficients (R²). The ANN analysis showed the high predictive performance, with high R² (0.9911), low SEP (0.45%), RPD (1.88), and RMSE (1.37%). The results of this study approved that alginate-gellan gum immobilized cells of <i>Paenibacillus taitungensis</i> strain MAHA-MIE could be effectively used for the handling of chromium (Cr⁶⁺).</p></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143749196","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A comprehensive review on microbial production and significant applications of multifunctional biomolecules: biosurfactants","authors":"Nisha Sharma,&nbsp;Yogesh K. Ahlawat,&nbsp;Arti Jamwal Sharma,&nbsp;Navneeti Chamoli,&nbsp;Monika Thakur,&nbsp;Anupriya Sharma,&nbsp;Sajid Mehmood,&nbsp;Anurag Malik,&nbsp;Meraj Ahmed,&nbsp;Himani Punia,&nbsp;Sumati Choubey","doi":"10.1007/s10532-025-10121-9","DOIUrl":"10.1007/s10532-025-10121-9","url":null,"abstract":"<div><p>Microorganisms are very well known potential sources of many novel metabolites and biosurfactants (green molecules). Biosurfactants are biobased molecules which are synthesized by bacteria, yeasts, fungi and actinomycetes. These biomolecules have emerged as multifunctional biomolecules of the 21st century due to their remarkable functional properties like low toxicity, enhanced effectiveness, selectivity, stability, high biodegradability and eco-friendly nature. These characteristics enable them to remain high effective under extreme conditions and play a significant role in environmental protection. Biosurfactants play a pivotal role in bioremediation technologies, offering an environmentally sustainable alternative for cleaning up contaminants. Their unique ability to reduce interfacial tension in liquids enables them to perform crucial functions such as biodegradation, emulsification, foam formation, surface activity, washing performance and detergent formulation. These versatile properties make biosurfactants invaluable across various industries, including environmental remediation, pharmaceuticals, agriculture and cosmetics. This review discusses the microbial production, characterization, industrial applications and ecological significance of biosurfactants. By highlighting their impact in the bioremediation of contaminants, this article underscores the potential of biosurfactants in advancing green technologies and addressing global environmental challenges.</p></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143740776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Challenges of exopolysaccharides production from polystyrene degradation by bacterium CHB 1.5 strain","authors":"Saijai Wattanasen,&nbsp;Pajongsuk Sutarut,&nbsp;Areeya Taengnoi,&nbsp;Salwa Torpee","doi":"10.1007/s10532-025-10122-8","DOIUrl":"10.1007/s10532-025-10122-8","url":null,"abstract":"<div><p>Polystyrene (PS), a substance that constitutes a significant portion of plastic waste, has resulted in environmental pollution and adverse health effects. Biodegradation and chemical transformation of PS are limited. However, biodegradation is one alternative way to reduce plastic pollution. This research aims to select plastic-degrading bacteria and produce exopolysaccharides (EPS) from plastic waste. Among the marine plastic waste at Chala tat Beach (Songkhla, Thailand), 35 rod-shaped and Gram-positive bacteria were found. The selected strains that exhibited the highest optical density (OD) at 600 nm were CHB1.5, CHD2.2, and CHC3.2. The efficiency of EPS production was tested and showed that CHB 1.5 could produce the maximum amount of EPS (13.47 ± 0.10 g/L) with a significant difference. After four weeks of plastic breakdown, CHB 1.5 had the highest total count (4.03 ± 0.02 Log CFU/mL), followed by CHD2.2 and CHC3.2 (3.99 ± 0.12 and 3.96 ± 0.02 Log CFU/mL, respectively). CHB 1.5 was also examined to use PS foam as a carbon source in modified Mineral Salt Medium for EPS production, with an EPS yield of 1.36 ± 0.08 g/L in week 4. The presence of amides I, polysaccharides, benzene rings, and hydroxyl groups (O–H) was detected by Fourier transform infrared spectroscopy. The Scanning Electron Microscope images confirmed the adherence of the CHB1.5 strain and EPS formation on the plastic sheet. In conclusion, the strain CHB1.5 showed promising potential for degrading PS plastic and producing EPS. Its qualities could be utilized in the future, as well as contribute to the reduction of plastic pollution in the environment in an eco-friendly way.</p></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143740775","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Enhanced bio-reduction of Cr(VI) using Shewanella putrefaciens CN32 mediated by Fe(III) minerals and riboflavin synergistically","authors":"Tianle Zhang,&nbsp;Haibo Li,&nbsp;Yichen Wu,&nbsp;Yajue Yuan,&nbsp;Yu Du","doi":"10.1007/s10532-025-10120-w","DOIUrl":"10.1007/s10532-025-10120-w","url":null,"abstract":"<div><p>Iron minerals and the coupling of electron shuttle media can effectively overcome the problem of the insolubility of iron minerals and the higher cross-medium resistance consequently to enhance the bio-reduction rate of Cr(VI) by dissimilatory metal-reducing bacteria (DMRB). This study explored the potential synergistic enhancement of Cr(VI) bio-reduction by <i>Shewanella putrefaciens</i> CN32 in combination with three iron minerals (ferrihydrite, goethite and hematite) and riboflavin (RF). The addition of RF accelerates the transfer of electrons from bacterial cells to Fe minerals, which in turn promotes the production of large amounts of Fe(II). The results indicated that compared to the control group, the Cr(VI) reduction rates in the CN32/RF/hematite, goethite, ferrihydrite systems increased to 93.03%, 91.07%, and 86.83%, hematite was capable of generating 2.24 mM Fe(II) due to its stable structure and efficient synergy with riboflavin. Enhancement factor(EF) was used to quantify the synergistic effect of RF and iron minerals on the bio-reduction of Cr(VI). At all three reaction times, the F_EF (K_CN32+RF+Fe/K_CN32) of three Fe(III) minerals were all greater than 1. XPS analysis revealed that the primary reduction products of Cr(VI) were identified as Cr(CH₃C(O)CHC(O)CH₃)₃, Cr₂O₃ and Fe(II)-Cr(III) hydroxide, were predominantly deposited on both bacterial and mineral surfaces, thereby influencing their synergistic interactions. This study unveiled the dynamic synergistic mechanism changes of Cr(VI) reduction in different iron minerals environment,which offers new ideas for the remediation of Cr(VI) pollution.</p><h3>Graphical Abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143688597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Recent perspectives on biotechnological production, modulation and applications of glycerophosphoryl diester phosphodiesterases","authors":"Arshia Nazir,&nbsp;Muhammad Sajjad","doi":"10.1007/s10532-025-10119-3","DOIUrl":"10.1007/s10532-025-10119-3","url":null,"abstract":"<div><p>Organophosphate (OP) compounds have been extensively employed as pesticides, insecticides and nerve agents. Stockpiles of chemical warfare agents must be destroyed as recommended by Chemical Weapon Convention (CWC). Toxicity of OP compounds to insects and mammals is due to their ability to inhibit the activity of acetylcholinesterase. Accumulation of acetylcholine leads to overstimulation of nerves, leading to convulsion, paralysis or even death. There is a dire need to decontaminate OP contaminated sites by using inexpensive and eco-friendly agents. Recently, OP hydrolyzing enzymes such as glycerophosphoryl diester phosphodiesterases (GDPDs) emerged as appealing agents to clean-up OP contaminated environmental sites. GDPDs are well known for enzymatic generation of glycerol 3-phosphate and corresponding alcoholic moiety from glycerophosphodiesters. Additionally, they are also involved in hydrolysis of OP compounds and degradative products of nerve agents. In the current review, structural and functional characteristics of GDPDs have been elaborated. Production of GDPDs from natural sources is quiet low so the current study aims at recombinant production of GDPDs from various sources. Comparative analysis of biochemical characteristics of various GDPDs indicated that thermostable GDPDs are active over broad temperature and pH range. In addition, thermostable GDPDs are resistant to high concentrations of organic solvents as well as metal ions. In order to enhance their practical utility, different engineering approaches (directed evolution, rational design and site-saturation mutagenesis) as well as immobilization strategies can be utilized to improve catalytic properties of GDPDs. Thus, the current review highlights the utilization of recombinant engineered free or immobilized GDPDs as tools in OP bioremediation.</p></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622076","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Advances in actinobacteria-based bioremediation: mechanistic insights, genetic regulation, and emerging technologies","authors":"Naureenbanu Makarani,&nbsp;Radhey Shyam Kaushal","doi":"10.1007/s10532-025-10118-4","DOIUrl":"10.1007/s10532-025-10118-4","url":null,"abstract":"<div><p>Untreated wastewater from sewage, industries, and agriculture contaminates ecosystems due to rapid population growth and industrialization. It introduces hazardous pollutants, including pesticides, polycyclic aromatic hydrocarbons (PAHs), and heavy metals, which pose serious health risks such as cancer, lung disorders, and kidney damage, threatening both environmental and human well-being. Using microorganisms for bioremediation is thought to be safer and more effective. Compared to other approaches, bioremediation is the most effective way to absorb heavy metals. Due to the high cost and unreliability of traditional remediation techniques, such as chemical and physical treatments, interest in bioremediation as an environmentally benign substitute has grown. Through the use of microorganisms, bioremediation successfully removes heavy metals and breaks down organic contaminants from contaminated circumstances. Actinobacteria are unique among these microbes because of their flexibility in metabolism and capacity to endure severe environments. They create secondary metabolites, such as enzymes, that help break down a variety of pollutants. Actinobacteria also produce siderophores and extracellular polymeric substances (EPS), which aid in trapping organic contaminants and immobilizing heavy metals. This review explores the diverse applications of actinobacteria in bioremediation, with a focus on their mechanisms for breaking down and neutralizing pollutants. We highlighted the advancements in bioremediation strategies, including the use of mixed microbial cultures, biosurfactants, nanoparticles and immobilized cell technologies which enhance the efficiency and sustainability of pollutant removal. The integration of omics technologies such as metagenomics, meta-transcriptomics, and meta-proteomics provides deeper insights into the genetic and metabolic pathways involved in bioremediation, suggesting the way for the development of genetically optimized strains with enhanced degradation capabilities. By leveraging these emerging technologies and microbial strategies, actinobacteria-mediated bioremediation presents a highly promising approach for mitigating environmental pollution. Ongoing research and technological advancements in this field can further enhance the scalability and applicability of bioremediation techniques, offering sustainable solutions for restoring contaminated ecosystems and protecting human health.</p><h3>Graphical abstract</h3>\u0000<div><figure><div><div><picture><source><img></source></picture></div></div></figure></div></div>","PeriodicalId":486,"journal":{"name":"Biodegradation","volume":"36 2","pages":""},"PeriodicalIF":3.1,"publicationDate":"2025-03-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143622075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}