Endocrinologia Diabetes Y Nutricion最新文献

{"title":"Association between the rs12654778 SNP of the β-2 adrenergic receptor and LDL cholesterol levels in the Chilean adult population","authors":"Carlos González-Contreras ,&nbsp;Miquel Martorell ,&nbsp;Natalia Ulloa ,&nbsp;Carolina Ochoa-Rosales ,&nbsp;Felipe Díaz-Toro ,&nbsp;Fanny Petermann-Rocha ,&nbsp;Carlos Celis-Morales ,&nbsp;Marcelo Villagran ,&nbsp;Lorena Mardones ,&nbsp;on behalf of the ELHOC Group (Epidemiology of Lifestyle and Health Outcomes in Chile)","doi":"10.1016/j.endien.2024.11.001","DOIUrl":"10.1016/j.endien.2024.11.001","url":null,"abstract":"<div><h3>Introduction</h3><div>Various polymorphisms in the beta-2 adrenergic receptor (<em>ADRB2</em>) gene have been associated with cardiometabolic risk factors, such as hypertension, dyslipidemia, type 2 diabetes mellitus and obesity contributing to the physiopathology of these chronic conditions. However, the association of the single nucleotide polymorphism (SNP) rs12654778 at the <em>ADRB2</em> gene with metabolic changes has been poorly studied and there is no information on the Chilean adult population.</div></div><div><h3>Objective</h3><div>To investigate the association between the rs12654778 SNP at the <em>ADRB2</em> gene with cardiometabolic risk markers in a Chilean adult population.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study including 404 participants from the GENADIO study whom were genotyped for rs12654778 and categorized into GG, AG, and AA genotypes. Associations with cardiometabolic risk markers, such as blood pressure, total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, triglycerides, blood glucose and insulin were examined using multivariate regression analysis, while statistical models were adjusted for sociodemographic and lifestyle variables.</div></div><div><h3>Results</h3><div>Our findings indicate a significant association between the presence of the protective genotype (AA) of the rs12654778 polymorphism and lower low-density lipoprotein cholesterol levels corresponding to 8.75<!--> <!-->mg/dL per each copy of the protective allele (maximally adjusted model). No significant associations were seen for the remaining variables.</div></div><div><h3>Conclusion</h3><div>The AA genotype of the rs12654778 SNP at the <em>ADRB2</em> gene had a protective effect specifically against low-density lipoprotein cholesterol levels. This is the first study ever conducted in Chile on this SNP of <em>ADRB2</em> and one of the few conducted worldwide to establish an association between the rs12654778 SNP at the <em>ADRB2</em> gene and LDL cholesterol.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 9","pages":"Pages 397-404"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721366","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart failure in people with diabetes and obesity, can it be prevented?","authors":"Jesús María de la Hera ,&nbsp;Elías Delgado","doi":"10.1016/j.endien.2024.10.001","DOIUrl":"10.1016/j.endien.2024.10.001","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 9","pages":"Pages 369-371"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Minimally invasive techniques for the management of benign thyroid nodules: Efficacy and impact on quality of life of percutaneous ethanol injection. Results from a high-resolution thyroid nodule unit","authors":"Javier Bodoque Cubas ,&nbsp;José Fernández Sáez ,&nbsp;Sergio Martínez Hervás ,&nbsp;José Vicente Gil Boix ,&nbsp;Juan José Salazar González ,&nbsp;Raquel María Pallarés Gassulla ,&nbsp;Sara Martínez Pérez ,&nbsp;Marcel la Miret Llauradó ,&nbsp;Iñaki Argüelles Jiménez ,&nbsp;Santiago Tofé Povedano","doi":"10.1016/j.endien.2024.11.003","DOIUrl":"10.1016/j.endien.2024.11.003","url":null,"abstract":"<div><h3>Background and objective</h3><div>The high incidence of thyroid nodular disease has raised concerns on the therapeutic management of benign thyroid nodules. The development of minimally invasive techniques is an alternative to surgery and has a low rate of complications. Our objective was to evaluate the safety and efficacy profile of percutaneous ethanol injections (PEI) with ethanol aspiration of symptomatic cystic and predominantly cystic thyroid nodules (cystic component &gt; 50%) treated in the thyroid nodule high-resolution unit (TNHRU) of Hospital de Tortosa Verge de la Cinta Hospital, Tarragona, Spain.</div></div><div><h3>Patients and methods</h3><div>The present work is a prospective, observational and descriptive study of 32 patients (87.5% women, mean age of 43; SD, 12) evaluated at the TNHRU from August 2022 through December 2023. Demographic data such as age, sex, previous thyroid function, diagnostic method, initial nodular volume, nodular composition and nodular location were analyzed. Using ultrasounds, measurements of diameters and thyroid nodule volume were taken. We aspirated a total of 50% of the cystic content and injected between 2 mL and 5 mL of 99% ethanol (depending on cystic volume). After letting the ethanol act inside the nodule for 5 to 10 minutes, all the cystic content and the injected ethanol were aspirated. We performed an ultrasound follow-up at 1, 3 and 6 months, calculating the total volume and the volume reduction rate (VRR). The impact on health-related quality of life (HRQoL) was assessed using the ThyPRO-39es questionnaire, which was administered before and after the PEI treatment at the 6-month follow-up.</div></div><div><h3>Results</h3><div>The median volume reduction at the end of the 6-month follow-up was 0.23 mL (0.00–0.67), and the VRR, 98.57% (94.80–100.00). The difference between the initial volume and the mean volume at the 1-, 3-, and 6-month follow-ups was statistically significant, as was the VRR between the 1-month and the 3- and 6-month follow-ups. Six patients (18.80%) required 2 PEIs and only 2 patients (6.3%) required 3 PEIs. The overall quality of life, which was scored from 0 (good) to 4 (poor), significantly improved from 1.28; SD, 0.81 up to 0.19; SD, 0.40 (p &lt; 0.001).</div></div><div><h3>Conclusions</h3><div>PEI is an effective alternative to treat cystic thyroid nodules resulting in an improved patients' HRQoL. It can be performed outpatiently with a low rate of complications, thus making it suitable for inclusion in the service portfolio of a HRTNU.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 9","pages":"Pages 380-389"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142645017","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Predictive value of circulating miR-409-3p for major adverse cardiovascular events in patients with type 2 diabetes mellitus and coronary heart disease","authors":"Liang Cao ,&nbsp;Xiangrong Pan ,&nbsp;Ying Li ,&nbsp;Wei Jia ,&nbsp;Jiayang Huang ,&nbsp;Jian Liu","doi":"10.1016/j.endien.2024.11.002","DOIUrl":"10.1016/j.endien.2024.11.002","url":null,"abstract":"<div><h3>Objectives</h3><div>To investigate the serum levels of miR-409-3p in patients with type 2 diabetes mellitus (T2DM) complicated with coronary heart disease (CHD) and its effect on high glucose (HG)-induced myocardial cell injury.</div></div><div><h3>Methods</h3><div>A total of 250 patients with T2DM admitted to our hospital from April 2020 through April 2022 were enrolled as the study subjects, and then grouped into T2DM<!--> <!-->+<!--> <!-->CHD (group #1) and T2DM (group #2). Real-time quantitative PCR (RT-qPCR) was used to measure the levels of serum miR-409-3p. The clinical performance of miR-409-3p was evaluated. The human cardiomyocyte AC16 cells were cultured in vitro and treated with HG. MTT assay and flow cytometry were performed to detect cell viability and apoptosis, respectively. Bioinformatic analyses were performed to explore the potential mechanism of miR-409-3p in T2DM complicated with CHD.</div></div><div><h3>Results</h3><div>The expression level of miR-409-3p was increased in the T2DM<!--> <!-->+<!--> <!-->CHD group and had a relative high diagnostic value for distinguishing patients with T2DM<!--> <!-->+<!--> <!-->CHD from patients with T2DM alone. Correlation analysis showed that serum miR-409-3p was positively associated with the Gensini score and adverse cardiovascular events; miR-409-3p knockdown alleviated HG-induced AC16 cell damage and reduced cell apoptosis. CREB1, BCL2, and SMAD2 were the top 3 hub genes of miR-409-3p.</div></div><div><h3>Conclusion</h3><div>Serum miR-409-3p may serve as a potential diagnostic and prognostic biomarker for predicting T2DM complicated with CHD and forecast adverse events. Targeting miR-409-3p may be a novel therapeutic strategy to intervene in the development of T2DM<!--> <!-->+<!--> <!-->CHD.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 9","pages":"Pages 372-379"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142721460","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Massive switch to an automated insulin delivery system in adults with type 1 diabetes previously treated with sensor-augmented pump due to high risk for hypoglycemia","authors":"Alex Mesa ,&nbsp;Daria Roca ,&nbsp;Montse Granados ,&nbsp;Irene Pueyo ,&nbsp;Carla Cabré ,&nbsp;Antonio J. Amor ,&nbsp;Clara Solà ,&nbsp;Olga Matas ,&nbsp;Júlia Castanys ,&nbsp;Ignacio Conget ,&nbsp;Marga Giménez","doi":"10.1016/j.endien.2024.11.004","DOIUrl":"10.1016/j.endien.2024.11.004","url":null,"abstract":"<div><h3>Introduction</h3><div>Automatic insulin delivery (AID) systems improve glycemic control and quality of life in individuals with type 1 diabetes (T1D). Our aim was to assess the feasibility, effectiveness, and safety of switching from a sensor-augmented pump (SAP) to AID in T1D subjects at high risk of hypoglycemia.</div></div><div><h3>Materials and methods</h3><div>A manufacturer-led program consisting of three sessions was implemented. Over three days, all patients completed the first session in-person, in groups of 6–12 people, to receive device training. Subsequently, the automatic mode was activated virtually (session 2), followed by online data download (session 3). Glucometric outcomes were evaluated after one month, along with serious adverse events (SAEs), technical incidents, and perceived satisfaction.</div></div><div><h3>Results</h3><div>The switch was performed in 125 patients, 56.8% of whom were women, with a mean age of 44.1 ± 14.9 years. 99.2% (n = 124) initialized auto-mode. There was an increase in time in range 70–180 mg/dL (64.3 ± 11.3 vs. 74.7 ± 11.2; p &lt; 0.001) and a decrease in time below 70 mg/dL (4.1 ± 3.9 vs. 2.0 ± 1.8; p &lt; 0.001) (N = 97). Forty-one related calls were received, with 10 requiring in-person visits. Medtronic technical service handled 92 related calls (0.74 per patient), from 47 different users (37.6%). One event of severe hypoglycemia was recorded as an SAE. Perceived security and satisfaction with the switch process were high in 91% and 92% of patients, respectively.</div></div><div><h3>Conclusions</h3><div>Massive switch from SAP to AID in T1D patients at high risk of hypoglycemia is feasible and safe through a hybrid program conducted in collaboration with the manufacturer.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 9","pages":"Pages 390-396"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142630704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Papillary thyroid carcinoma on thyroglossal duct cyst: A series of 7 cases","authors":"Belén M. Martínez Mulero,&nbsp;Julia Sastre Marcos,&nbsp;María Ruiz de Ancos,&nbsp;Alejandro Raúl Gratacós Gómez,&nbsp;Lucía Manzano Valero","doi":"10.1016/j.endien.2024.09.004","DOIUrl":"10.1016/j.endien.2024.09.004","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 8","pages":"Pages 365-367"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142146601","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Prevalence of hypogonadism in men with and without chronic obstructive pulmonary disease: A cross-sectional study","authors":"Horacio Matías Castro ,&nbsp;Pablo Knoblovits ,&nbsp;Joaquin Maritano Furcada ,&nbsp;Eduardo Luis De Vito ,&nbsp;Sebastían Matias Suarez ,&nbsp;Pablo Rene Costanzo","doi":"10.1016/j.endien.2024.09.006","DOIUrl":"10.1016/j.endien.2024.09.006","url":null,"abstract":"<div><h3>Background</h3><div>Hypogonadism is a common finding of chronic obstructive pulmonary disease (COPD). However, the prevalence of hypogonadism in COPD varies among studies. The aim of this study was to determine and compare the prevalence of hypogonadism in men with and without COPD.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study with 134 patients with stable COPD and 70 age-matched men with non-COPD. Hypogonadism was defined by the presence of symptoms according to the Androgen Deficiency in Aging Males questionnaire, along with total testosterone deficiency (&lt;300<!--> <!-->ng/dL).</div></div><div><h3>Results</h3><div>Patients had a mean age of 68 years (SD, 6), a body mass index of 28<!--> <!-->kg/m² (SD, 6), and 17% were current smokers. The prevalence of hypogonadism was 41.8% in COPD men (<em>N</em> <!-->=<!--> <!-->56, 95%CI, 33–51) and 10.0% in non-COPD men (<em>N</em> <!-->=<!--> <!-->7, 95%CI, 4–20), with a prevalence ratio of 4.2 (95%CI, 2.0–8.7, <em>p</em> <!-->&lt;<!--> <!-->0.001). The prevalence of low total testosterone concentrations (&lt;300<!--> <!-->ng/dL) were significantly higher in COPD patients vs the control group (47.0% vs 15.7%, <em>p</em> <!-->=<!--> <!-->&lt;0.001). In the COPD group, 89.3% of patients had hypogonadotropic hypogonadism and 10.7%, hypergonadotropic hypogonadism. The prevalence of hypogonadism was higher in severe vs non-severe COPD patients (55.8% vs 35.2%; <em>p</em> <!-->=<!--> <!-->0.024).</div></div><div><h3>Conclusions</h3><div>The prevalence of hypogonadism was high and greater in COPD vs non-COPD men. This study suggests that COPD patients should be screened for hypogonadism.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 8","pages":"Pages 348-354"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394371","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Increased incidence of pediatric type 1 diabetes during the pandemic in Biscay, Spain","authors":"Concepción Fernández-Ramos ,&nbsp;Eunate Arana-Arri ,&nbsp;Amaia Vela ,&nbsp;Inés Urrutia ,&nbsp;Borja Santos Zorrozua ,&nbsp;Itxaso Rica","doi":"10.1016/j.endien.2024.09.002","DOIUrl":"10.1016/j.endien.2024.09.002","url":null,"abstract":"<div><h3>Objective</h3><div>To update the incidence rate (IR) and trends of type 1 diabetes mellitus (T1DM) in children aged 0–14 years from 2003 to 2022, in Biscay, Spain.</div></div><div><h3>Subjects and method</h3><div>We used the capture–recapture method: primary cases were prospectively extracted from the hospital registry and a secondary independent data source was obtained from diabetes associations and a public health database. The IRs standardized by age and sex were calculated using the direct method, assuming an equal distribution in each age/sex group. The IR occurring during the various COVID-19 waves was compared with the pre-pandemic IR.</div></div><div><h3>Results</h3><div>A total of 378 new cases were identified. The mean age at diagnosis was 9.7 years (5.8–11.9). The completeness of ascertainment was 99.1%. The mean annual age-standardized IR was 12.92 (95%CI, 11.35–13.91). The mean IRs for the 0–4, 5–9, and 10–14 age groups were 7.67, 13.41 and 17.83 cases/100,000 children/year, respectively. The IR trend was statistically significant in the entire group and in the 5–9 year-old group with a mean annual increase of 1.9% (95%CI, 0.1–3.8) and 3.3% (95%CI, 1.002–1.065); <em>p</em> <!-->=<!--> <!-->0.039.</div><div>The 5-year period analysis confirmed that the increase was significant only in the last 5 years (20%). When 2020–2022 (pandemic) and 2017–2019 (pre-pandemic) periods were compared this difference goes up to 44.5%; <em>p</em> <!-->=<!--> <!-->0.029.</div></div><div><h3>Conclusions</h3><div>After a long period of stability in the IR of T1DM in children younger than 15 years of age in Biscay, Spain, an increase in recent years has been reported, which is consistent with the SARS-CoV2 pandemic, with the largest increase being reported in the 5-to 9-year-old age group.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 8","pages":"Pages 332-339"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394423","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical significance of pituitary adenoma consistency in patients undergoing endoscopic transsphenoidal surgery","authors":"Alberto Acitores Cancela ,&nbsp;Víctor Rodríguez Berrocal","doi":"10.1016/j.endien.2024.09.003","DOIUrl":"10.1016/j.endien.2024.09.003","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 8","pages":"Pages 321-323"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142298954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Exploring plantar pressure distribution in patients with newly diagnosed diabetes: Implications for foot ulcer prevention in an overweight Mexican population","authors":"Francis Rojas-Torres ,&nbsp;Héctor Infanzón-Talango ,&nbsp;Ana Cristina García-Ulloa ,&nbsp;Sergio Hernández-Jiménez ,&nbsp;Gerardo Rodríguez-Reyes","doi":"10.1016/j.endien.2024.09.007","DOIUrl":"10.1016/j.endien.2024.09.007","url":null,"abstract":"<div><h3>Introduction</h3><div>Elevated plantar pressure (PP) constitutes a risk factor for developing foot ulcers. Once present, elevated PP increases morbidity and mortality in patients with diabetes. Given the high prevalence of overweight and obesity in the Mexican population, this study aimed to describe the magnitudes and the distribution of the PP observed in a sample of newly diagnosed patients with diabetes, adjusting for body mass index (BMI) groups (normal weight, overweight, grade I obesity, and grade II and III obesity).</div></div><div><h3>Materials and methods</h3><div>A total of 250 volunteers attending a comprehensive care program for the management of type 2 diabetes received foot assessments that included vascular and neurological evaluation, the identification of musculoskeletal changes, and measurements of PP.</div></div><div><h3>Results</h3><div>Diabetic neuropathy and peripheral arterial disease were present in 21.6% and 11.2% of all participants. Musculoskeletal alterations were present in 70.8% of participants. A positive and significant correlation (<em>p</em> <!-->&lt;<!--> <!-->0.001) was observed between BMI and the peak PP of all anatomical regions assessed. After adjusting for BMI, significant differences (<em>p</em> <!-->&lt;<!--> <!-->0.001) were seen between groups. The metatarsal region, particularly under the third metatarsal head, denoted the highest magnitudes across all BMI.</div></div><div><h3>Conclusions</h3><div>Periodic PP assessment is recommended to identify the distribution of high-pressure points along the plantar surface. However, as a preventive measure, it is suggested to encourage patients with diabetes and overweight or obesity to wear appropriate footwear and pressure-relief insoles to relieve high-pressure areas – often seen in these populations – to help prevent foot complications.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 8","pages":"Pages 340-347"},"PeriodicalIF":1.8,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142394422","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}