{"title":"Lipoprotein (a): Is its systematic determination indicated?","authors":"Manuel Antonio Botana López","doi":"10.1016/j.endien.2024.02.005","DOIUrl":"10.1016/j.endien.2024.02.005","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 5","pages":"Pages 191-193"},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141248827","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Repetition of thyroid fine-needle aspiration cytology after an initial nondiagnostic result: Is there an optimal timing?","authors":"Inês Cosme , Ema Nobre , Maria João Bugalho","doi":"10.1016/j.endien.2024.03.018","DOIUrl":"https://doi.org/10.1016/j.endien.2024.03.018","url":null,"abstract":"<div><h3>Introduction</h3><p>It is suggested to wait at least 3 months to repeat a fine needle aspiration cytology (FNAC) to avoid possible inflammatory cytological changes induced by a previous procedure. This study evaluated the influence of the interval between 2 FNACs in a cohort with a previous non-diagnostic (ND) FNAC. We analysed the occurrence of ND or atypia of undetermined significance/follicular lesion of undetermined significance (AUS/FLUS) results in the second FNAC, based on the intervals between procedures.</p></div><div><h3>Patients and methods</h3><p>Retrospective study (2017–2020) including thyroid nodules with a ND result, subjected to another FNAC. Demographic, clinical and echographic data, interval between FNACs and their results were collected. We considered the intervals: ≤/>3 months and ≤/>6 months. Second FNAC results were classified as ND, AUS/FLUS or diagnostic (including the other Bethesda categories).</p></div><div><h3>Results</h3><p>Included 190 nodules (190 patients – 82.1% women, mean age 60<!--> <!-->±<!--> <!-->13.7 years) with a first ND FNAC. The second FNAC results were: ND in 63 cases, AUS/FLUS in 9 and diagnostic in 118 cases. There were no statistical differences in FNAC results performed<!--> <!-->≤<!--> <!-->3 months (13 ND, 2 AUS/FLUS, 19 diagnostic) vs >3 months (50 ND, 7 AUS/FLUS, 99 diagnostic; <em>p</em> <!-->=<!--> <!-->0.71). Similarly, there were no statistical differences considering a longer time interval: ≤6 months (32 ND, 3 AUS/FLUS, 59 diagnostic) vs >6 months (31 ND, 6 AUS/FLUS, 59 diagnostic; <em>p</em> <!-->=<!--> <!-->0.61).</p></div><div><h3>Conclusions</h3><p>Time interval between FNACs was not relevant to the final cytological result. Early FNAC repetition did not increase the cases of ND or AUS/FLUS.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 5","pages":"Pages 216-220"},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141423781","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation of dietary inflammation index and dietary pattern with mild cognitive impairment in patients with type 2 diabetes","authors":"Shengdan Pu, Yuxin Xu, Xuewei Tong, Yitong Zhang, Xiaotong Sun, Xinyuan Gao","doi":"10.1016/j.endien.2024.01.008","DOIUrl":"https://doi.org/10.1016/j.endien.2024.01.008","url":null,"abstract":"<div><h3>Objective</h3><p>We aimed to determine the dietary patterns associated with mild cognitive impairment (MCI) in type 2 diabetes (T2DM) and the correlation of dietary inflammatory index (DII) with MCI.</p></div><div><h3>Methods</h3><p>The Montreal Cognitive Assessment (MoCA) was used to assess cognitive function. A semi-quantitative food frequency questionnaire was used to collect dietary data and calculate DII. Dietary patterns were determined by reduced-rank regression (RRR), grouping dietary pattern scores and DII into quartiles, with logistic regression for correlation analysis. Dose–response relationships between dietary pattern scores, DII and diabetic MCI were explored using restricted cubic splines (RCS). A mediation analysis was performed to investigate whether DII mediates the association between dietary patterns and MCI.</p></div><div><h3>Results</h3><p>In the “Mediterranean-style dietary pattern”, the multivariable-adjusted odds ratio of having MCI was 0.37 (95% CI: 0.20–0.68; <em>p</em> for trend<!--> <!-->=<!--> <!-->0.002) in the highest versus lowest quartiles of the dietary score. In the “high-meat and low-vegetable pattern”, the multivariable-adjusted odds ratio of having MCI was 6.84 (95% CI: 3.58–13.10; <em>p</em> for trend<!--> <!--><<!--> <!-->0.001) in the highest versus lowest quartiles of the dietary score. In the “Western-style dietary pattern”, the multivariable-adjusted odds ratio of having MCI was 2.48 (95% CI: 1.38–4.46; <em>p</em> for trend<!--> <!-->=<!--> <!-->0.001). The multivariable-adjusted odds ratio of having MCI was 3.99 (95% CI: 2.14–7.42; <em>p</em> for trend<!--> <!--><<!--> <!-->0.001) in the highest versus lowest quartiles of DII.</p><p>There is a non-linear dose–response relationship between the “high-meat and low-vegetable pattern” score and the prevalence of MCI, as well as the DII and the prevalence of MCI. The DII partially mediated the impact of the “Mediterranean-style dietary pattern” and the “high-meat and low-vegetable pattern” on MCI.</p></div><div><h3>Conclusion</h3><p>In T2DM patients, greater adherence to the “Mediterranean-style dietary pattern” is associated with a lower probability of having MCI. However, excessive consumption of meat, especially red meat and processed meat, combined with a lack of vegetable intake, is associated with a higher probability of having MCI. Greater adherence to the “Western-style dietary pattern” is associated with a higher probability of having MCI. In addition, a pro-inflammatory diet is associated with a higher probability of having MCI, and DII partially mediates the impact of dietary patterns on MCI.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 4","pages":"Pages 152-162"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140901935","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emilia Gómez Hoyos , Patricia Cabrera García , Marcelino Gómez Balaguer , on behalf of the Gonad, Identity and Sexual Differentiation working group of the Spanish Society of Endocrinology and Nutrition (GT-GIDSEEN)
{"title":"Executive summary: Quality standards of care units for people with sexual and gender diversity","authors":"Emilia Gómez Hoyos , Patricia Cabrera García , Marcelino Gómez Balaguer , on behalf of the Gonad, Identity and Sexual Differentiation working group of the Spanish Society of Endocrinology and Nutrition (GT-GIDSEEN)","doi":"10.1016/j.endien.2024.01.006","DOIUrl":"10.1016/j.endien.2024.01.006","url":null,"abstract":"<div><p>Comprehensive biopsychosocial care for people with gender incongruence (ICD 11) who are transgender (trans) or gender diverse is a complex process in which the quality of the medical transition can only be guaranteed after a multidisciplinary approach, through teams that integrate professionals with training and experience not only in medicine but also in diversity and gender identity. Based on this, the Gonad, Identity and Sexual Differentiation working group of the Spanish Society of Endocrinology and Nutrition (GT-GIDSEEN) has established minimum care requirements that aim to guarantee adequate health care for these people by professionals. A position paper has been produced and is available at <span>https://www.seen.es/portal/documentos/estandares-calidad-gidseen-2024</span><svg><path></path></svg>.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 4","pages":"Pages 181-186"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877688","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Laura Costa , Emma Garcia-Grau , Laura Toledo , Nuria Burgaya , Ramon Cos , Mireia Rojas , Olga Giménez-Palop , Assumpta Caixas
{"title":"Herlyn–Werner–Wunderlinch: An unusual presentation in a patient with Prader–Willi syndrome","authors":"Laura Costa , Emma Garcia-Grau , Laura Toledo , Nuria Burgaya , Ramon Cos , Mireia Rojas , Olga Giménez-Palop , Assumpta Caixas","doi":"10.1016/j.endien.2024.01.010","DOIUrl":"https://doi.org/10.1016/j.endien.2024.01.010","url":null,"abstract":"<div><p>Herlyn–Werner–Wunderlich syndrome is an uncommon urogenital anomaly defined by uterus didelphys, obstructed hemi-vagina and unilateral renal anomalies. The most common clinical presentation is dysmenorrhoea following menarche, but it can also present as pain and an abdominal mass.</p><p>Prader–Willi syndrome is a rare neuroendocrine genetic syndrome. Hypothalamic dysfunction is common and pituitary hormone deficiencies including hypogonadism are prevalent.</p><p>We report the case of a 33-year-old female with Prader–Willi syndrome who was referred to the Gynaecology clinic due to vaginal bleeding and abdominal pain. Abdominal ultrasound revealed a haematometra and haematocolpos and computed tomography showed a uterus malformation and a right uterine cavity occupation (hematometra) as well as right kidney agenesis.</p><p>Vaginoscopy and hysteroscopy were performed under general anaesthesia, finding a right bulging vaginal septum and a normal left cervix and hemiuterus. Septotomy was performed with complete haematometrocolpos drainage. The association of the two syndromes remains unclear.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 4","pages":"Pages 171-176"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140901936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Andrés Ruiz de Assín Valverde, José Joaquín Alfaro Martínez, María Carmen López García, Marina Jara Vidal, Marta Gallach Martínez, Noel Roig-Marin, Rosa Pilar Quílez Toboso, César Gonzalvo Díaz, Lourdes García Blasco, Pedro José Pinés Corrales, Cristina Lamas Oliveira, Silvia Aznar Rodríguez, Elena Parreño Caparrós, Luz María López Jiménez
{"title":"Evolution of interconsultal activity to endocrinology and nutrition in hospitalization floor in a third level hospital","authors":"Andrés Ruiz de Assín Valverde, José Joaquín Alfaro Martínez, María Carmen López García, Marina Jara Vidal, Marta Gallach Martínez, Noel Roig-Marin, Rosa Pilar Quílez Toboso, César Gonzalvo Díaz, Lourdes García Blasco, Pedro José Pinés Corrales, Cristina Lamas Oliveira, Silvia Aznar Rodríguez, Elena Parreño Caparrós, Luz María López Jiménez","doi":"10.1016/j.endien.2024.04.002","DOIUrl":"10.1016/j.endien.2024.04.002","url":null,"abstract":"<div><h3>Introduction</h3><p>Endocrinology and Nutrition (EyN) is an outpatient and hospital medical specialty. This study aims to understand the evolution of the activity of interdepartmental consultation (IC) carried out by EyN in hospitalization floor of a third level hospital, comparing its evolution with other medical specialties, and comparing endocrine IC with nutritional IC.</p></div><div><h3>Material and methods</h3><p>Longitudinal and retrospective study which analyzes IC notes of EyN and other medical specialties between 01-01-2013 and 31-12-2022.</p></div><div><h3>Results</h3><p>A total of 76093 IC notes (12623 patients) were performed by the EyN service (average age 65.4 years; 59% male) with an average of 4.8 notes per patient. Average annual growth was 7% in notes and 4% in patients (versus 6% and 3% of all other medical services, differences statistically significant). Of all patients hospitalized for 4 or more days, EyN went from attending 7.9% (2013) to 12.3% (2022). 66% of the IC performed by EyN was for nutritional cause and 34% for other pathologies.</p></div><div><h3>Conclusions</h3><p>The EyN service is the one that most patients attend in hospital IC activity, with growth over the last few years greater than other medical specialties. Nutritional pathology is the main reason for IC</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 4","pages":"Pages 163-170"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140877687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Álvaro Valverde Márquez, María Teresa Mories Álvarez, Heather Stacey Villanueva Alvarado, Ximena Carolina Vivas Vaca, Manuel Delgado Gómez
{"title":"Fighting thyrotoxicosis with therapeutic plasma exchange: A case report","authors":"Álvaro Valverde Márquez, María Teresa Mories Álvarez, Heather Stacey Villanueva Alvarado, Ximena Carolina Vivas Vaca, Manuel Delgado Gómez","doi":"10.1016/j.endien.2024.01.009","DOIUrl":"https://doi.org/10.1016/j.endien.2024.01.009","url":null,"abstract":"<div><p>Thyrotoxicosis is the clinical condition resulting from an excess of thyroid hormones for any reason. The main causes are Graves–Basedow disease, toxic multinodular goitre and toxic adenoma. The medical treatment to control thyroid function includes antithyroid drugs, beta blockers, iodine solutions, corticosteroids and cholestyramine. Although therapeutic plasma exchange is not generally part of the therapy, it is an alternative as a preliminary stage before the definitive treatment.</p><p>This procedure makes it possible to eliminate T4, T3, TSI, cytokines and amiodarone. In most cases, more than one cycle is necessary, either daily or every three days, until clinical improvement is observed. The effect on thyrotoxicosis is temporary, with an approximate duration of 24–48<!--> <!-->h.</p><p>This approach has been proposed as a safe and effective alternative when the medical treatment is contraindicated or not effective, and when there is multiple organ failure or emergency surgery is required.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 4","pages":"Pages 177-180"},"PeriodicalIF":1.9,"publicationDate":"2024-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140901937","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}