Endocrinologia Diabetes Y Nutricion最新文献

{"title":"Executive summary. Screening, staging and follow-up of type 1 diabetes in preclinical stages: Consensus of the scientific societies SED, SEEN and SEEP.","authors":"María Asunción Martínez-Brocca, Virginia Bellido, Roque Cardona-Hernandez, Luis Castaño, Ignacio Conget, Alberto Fernández, Ana Lucía Gómez Gila, Isabel Leiva-Gea, Dídac Mauricio","doi":"10.1016/j.endien.2025.501639","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501639","url":null,"abstract":"<p><p>Type 1 diabetes (T1D) is an autoimmune disease whose late diagnosis can lead to serious complications such as diabetic ketoacidosis, especially in children. The presence of specific autoantibodies allows for the identification of a presymptomatic phase, opening the door to screening strategies targeting populations at high genetic risk, such as first-degree relatives. This document presents the consensus recommendations of the Spanish Diabetes Society (SED), the Spanish Society of Endocrinology and Nutrition (SEEN) and the Spanish Society of Paediatric Endocrinology (SEEP) on the screening, staging and monitoring of T1D in preclinical stages. Early identification of the disease will enable a personalised approach to be established, promote health education and, eventually, consider therapeutic interventions that may delay progression to the symptomatic phase. This consensus seeks to establish a common framework for clinical action based on the available evidence, with clear recommendations for its proper implementation.</p>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501639"},"PeriodicalIF":1.8,"publicationDate":"2025-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145330442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"From COVID-19 telemedicine to artificial intelligence telemedicine.","authors":"Ana Zugasti Murillo, Juan José Gorgojo Martínez","doi":"10.1016/j.endien.2025.501595","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501595","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501595"},"PeriodicalIF":1.8,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309615","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Gastroileal bypass reversal as a treatment for iatrogenic hyperparathyroidism and refractory hypocalcemia.","authors":"Bryan-Josué Flores-Robles, Juan Antonio López Martín, María Jesús Chinchetru Ranedo, José Miguel Lázaro Guevara, José Fernando Marín Díez, Núria Guañabens","doi":"10.1016/j.endien.2025.501632","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501632","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501632"},"PeriodicalIF":1.8,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309619","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Delphi Consensus of the Nutrition Area of ​​the SEEN (NutriSEEN) on the use of enteral tube nutrition in people with advanced dementia.","authors":"Francisco Pita Gutiérrez, Irene Breton Lesmes, Julia Álvarez Hernández, María D Ballesteros-Pomar, Rocío Campos Del Portillo, Ana Hernández Moreno, Francisco Botella Romero","doi":"10.1016/j.endien.2025.501640","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501640","url":null,"abstract":"<p><strong>Introduction: </strong>Despite the available scientific evidence, the use of enteral tube feeding in people with advanced dementia is currently controversial. Given this situation, and following the position paper promoted by the SEEN (Spanish Society of Endocrinology and Nutrition), a consensus is sought to contribute to improving the management of this condition.</p><p><strong>Material and methods: </strong>A Delphi consultation was conducted, a formal and systematic method for obtaining consensus. The project was developed in the following stages: (1) questionnaire development by the Scientific Committee; (2) first round of Delphi consultation; (3) second round of Delphi consultation, and; (4) a meeting to present the results.</p><p><strong>Results: </strong>A total of 340 expert members of the SEEN Nutrition Department were invited to participate through the society itself. Of these, 128 panellists completed the questionnaire in the first round (response rate of 38%) and 53 in the second round (response rate of 41%, compared to the first round). Of the 24 statements initially proposed, 14 (58%) reached consensus. Of these, 13 achieved this goal in the first round and one in the second.</p><p><strong>Conclusions: </strong>Advanced dementia represents a significant challenge for both healthcare professionals and patients' families, raising ethical and practical dilemmas regarding appropriate treatment and management to improve the quality of life of those affected. This paper draws several key conclusions that can guide the care and attention of these patients.</p>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501640"},"PeriodicalIF":1.8,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309630","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Current status of iodisation in pregnant women in Asturias, Spain.","authors":"Carmen Sánchez Blanco, Marina García Cancelo, Cristina González Martínez, Leire Cardo González, Marta Diéguez Felechosa","doi":"10.1016/j.endien.2025.501646","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501646","url":null,"abstract":"<p><strong>Introduction: </strong>Although former studies indicated that Asturias (Spain) is an iodine-sufficient region, preliminary data suggest this trend may be changing.</p><p><strong>Objective: </strong>To determine the prevalence of iodine deficiency in pregnant women in Asturias.</p><p><strong>Material and methods: </strong>We designed an observational, prospective, multicenter study. The urinary iodine concentration (UIC) of 371 pregnant women was analyzed between November 2021 and March 2023. Participants were recruited from the three central areas of the Principality of Asturias (Areas III, IV, and V). The project received approval from the Research Ethics Committee of the Principality of Asturias (RECPA).</p><p><strong>Results: </strong>A total of 52% of pregnant women had urinary iodine levels indicative of iodine deficiency (< 150 μg/L). The average UIC in our cohort was 146 μg/L. We compared thyroid-stimulating hormone (TSH) levels between pregnant women with iodine deficiency and those with sufficient iodine, but found no statistically significant differences in TSH levels between the two groups. We also couldn't establish statistically significant links between iodine deficiency status and body mass index (BMI), number of previous births, nationality, or age. Furthermore, iodine deficiency did not show a significant link to obstetric complications such such as hypertension during pregnancy or premature birth.</p><p><strong>Conclusions: </strong>These findings support the hypothesis of an increase in iodine deficiency during the first trimester of pregnancy in our population. This highlights the urgent need to review our supplementation strategies and nutritional education programs.</p>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501646"},"PeriodicalIF":1.8,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309585","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fish-eye disease. Altered HDL cholesterol metabolism and corneal involvement: A case report.","authors":"Ana Álvarez ODogherty, Carmen Rodríguez Jiménez, Amaya Belanger-Quintana, Sonia Rodríguez Novoa, Francisco Arrieta Blanco","doi":"10.1016/j.endien.2025.501638","DOIUrl":"https://doi.org/10.1016/j.endien.2025.501638","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":" ","pages":"501638"},"PeriodicalIF":1.8,"publicationDate":"2025-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145309560","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Coexistance of metastatic papillary thyroid microcarcinoma and medullary thyroid carcinoma in MEN 2B. Case report and literature review","authors":"María Díaz-Tobarra ,&nbsp;Sara Subirats Bort ,&nbsp;Ignacio Peña Saiz de Aja ,&nbsp;Gonzalo Villar García ,&nbsp;Encarnación Lag Asturiano","doi":"10.1016/j.endien.2025.501596","DOIUrl":"10.1016/j.endien.2025.501596","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 8","pages":"Article 501596"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145058792","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Neuromedin U and BMI correlation in T1DM and T2DM vs healthy controls: A comparative study","authors":"Yasemin Çalışkan ,&nbsp;Emre Sarandöl ,&nbsp;Nizameddin Koca","doi":"10.1016/j.endien.2025.501631","DOIUrl":"10.1016/j.endien.2025.501631","url":null,"abstract":"<div><h3>Objective</h3><div>This study aimed to assess serum Neuromedin U (NmU) levels in patients with Type 1 (T1DM) and Type 2 diabetes mellitus (T2DM) vs healthy controls and evaluate the correlation between NmU and body mass index (BMI).</div></div><div><h3>Research design and methods</h3><div>We conducted a cross-sectional study with 134 participants: 45 with T1DM, 49 with T2DM, and 40 healthy controls. Serum NmU levels were measured using enzyme-linked immunosorbent assay (ELISA), and the correlation with BMI was assessed.</div></div><div><h3>Results</h3><div>NmU levels were not significantly different between diabetic patients and healthy controls. No significant correlation was observed between NmU and BMI in T1DM or T2DM groups. However, the healthy control group found a significant inverse correlation between NmU and BMI (rho<!--> <!-->=<!--> <!-->−0.373, <em>p</em> <!-->&lt;<!--> <!-->0.05).</div></div><div><h3>Conclusions</h3><div>NmU may not be a direct biomarker for diabetes, but its significant correlation with BMI in healthy individuals suggests a potential role in metabolic regulation. This is the first study ever conducted to compare NmU levels across diabetic subtypes, offering novel insights into the role of in metabolic homeostasis.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 8","pages":"Article 501631"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236393","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Therapeutic effects of chromium supplementation on women with polycystic ovarian syndrome: A systematic review and meta-analysis","authors":"Mohammed Hamsho ,&nbsp;Yazan Ranneh ,&nbsp;Abdulmannan Fadel","doi":"10.1016/j.endien.2025.501578","DOIUrl":"10.1016/j.endien.2025.501578","url":null,"abstract":"<div><h3>Background</h3><div>Polycystic ovarian syndrome (PCOS) has been treated recently with chromium supplementations. However, it is unknown if this dietary supplement has similar effect to metformin.</div></div><div><h3>Aim</h3><div>The aim of this study was to investigate the efficacy of chromium supplementation in women with PCOS.</div></div><div><h3>Methods</h3><div>A meta-analysis was conducted using relevant articles obtained from searches of PubMed, Scopus, Embase, and Google Scholar. The mean difference and standardized mean difference were employed to determine the effect size for biochemical parameters.</div></div><div><h3>Results</h3><div>A total of 10 randomized controlled trials involving 683 women were included in the analysis. The results indicated that chromium supplementation, as vs a placebo, significantly decreased fasting blood insulin (<em>P</em> <!-->=<!--> <!-->0.01), triglyceride (<em>P</em> <!-->&lt;<!--> <!-->0.00001), total cholesterol (<em>P</em> <!-->&lt;<!--> <!-->0.00001), very low-density lipoprotein (<em>P</em> <!-->&lt;<!--> <!-->0.00001), low-density lipoprotein (<em>P</em> <!-->=<!--> <!-->0.0003), high sensitivity C-reactive protein (<em>P</em> <!-->=<!--> <!-->0.02), malondialdehyde (<em>P</em> <!-->=<!--> <!-->0.007), follicle stimulating hormone (<em>P</em> <!-->=<!--> <!-->0.0007), and prolactin (<em>P</em> <!-->=<!--> <!-->0.01), and increased the Quantitative Insulin Sensitivity Check Index (<em>P</em> <!-->=<!--> <!-->0.02), total antioxidant capacity (<em>P</em> <!-->&lt;<!--> <!-->0.0001), and ovulation incidence (<em>P</em> <!-->=<!--> <!-->0.001). Chromium supplementation was also found to be more effective than metformin in reducing HOMA-IR (<em>P</em> <!-->&lt;<!--> <!-->0.00001), and luteinizing hormone (<em>P</em> <!-->=<!--> <!-->0.04).</div></div><div><h3>Conclusion</h3><div>Chromium picolinate supplementation at a dosage of 200<!--> <!-->μg may provide benefits similar to metformin with regard to FBG, FBI, ovulation, and pregnancy incidence, with fewer side effects in patients with PCOS. Further experiments are still required to draw effective dietary guidelines related to chromium.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 8","pages":"Article 501578"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236396","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Active insulin time setting in MiniMed™ 780G: Impact on glucose control and patient perception","authors":"Fidel Jesús Enciso Izquierdo ,&nbsp;María José Amaya García ,&nbsp;Paula Gómez Turégano ,&nbsp;María Luengo Andrada ,&nbsp;Ana Alejandra Cordero Vaquero ,&nbsp;José Antonio Lucas Gamero ,&nbsp;Sergio Garrido Domínguez ,&nbsp;Irene Álvarez Reyes","doi":"10.1016/j.endien.2025.501635","DOIUrl":"10.1016/j.endien.2025.501635","url":null,"abstract":"<div><h3>Introduction</h3><div>The active insulin time (AIT) is an adjustable parameter of the MiniMed™ 780G (MM780G) system. We analyze glucose outcomes and patient perception at different AIT settings.</div></div><div><h3>Method</h3><div>We conducted a quasi-experimental study on type 1 diabetes mellitus patients treated with MM780G, seen consecutively in our center. AIT was set at 2, 3 and 4<!--> <!-->h consecutively, during a 2-week period each. Glucose metrics, insulin delivery and a questionnaire about patient perception were evaluated. At the end, results were discussed with the patient and the most appropriate AIT was agreed upon.</div></div><div><h3>Results</h3><div>A total of 58 users were included, aged 18–65 years, 58.6% of whom were women. At baseline, 2-h AIT was set in 6.70% of the patients, &gt;2-h AIT and ≤3-h AIT in 24.67%, &gt;3-h AIT and ≤4-h AIT in 58.62%, and &gt;4-h AIT in 10.34%. Under the 2-h AIT, TIR increased by 2.28% and 6.35% vs 3- and 4-h AIT, respectively. The auto-correction boluses percentage was 21.19% at 2-h AIT, 16.90% at 3-h AIT and 14.40% at 4-h AIT.</div><div>A total of 41.4% of the users considered that 3<!--> <!-->h was the AIT that most met their needs and 43.1% felt safer and less vulnerable to hypoglycemia at this setting. After trying on different AIT durations, 2<!--> <!-->h increased from 6.7% of participants to 62%.</div></div><div><h3>Conclusion</h3><div>At 2-h AIT, the system delivers more auto-correction insulin and improves TIR vs 3- and 4-h AIT. Patients feel safer and less susceptible to hypoglycemia at 3-h AIT, but 2 out of 3 would rather choose the 2-h AIT after knowing glycemic outcomes.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 8","pages":"Article 501635"},"PeriodicalIF":1.8,"publicationDate":"2025-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145236394","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}