Endocrinologia Diabetes Y Nutricion最新文献

{"title":"Diabetes and jaundice in young patients. The importance of extrapancreatic manifestations in the typing of diabetes mellitus","authors":"Víctor José Simón Frapolli, Miguel Damas Fuentes, María José Picón César, Andrea Fernández Valero, Francisco José Tinahones Madueño","doi":"10.1016/j.endien.2024.03.004","DOIUrl":"10.1016/j.endien.2024.03.004","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 2","pages":"Pages 90-91"},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140898","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of semaglutide on weight loss and glycaemic control in patients with Prader–Willi Syndrome and type 2 diabetes","authors":"Olga Giménez-Palop ,&nbsp;Ana Romero ,&nbsp;Laia Casamitjana ,&nbsp;Rocio Pareja ,&nbsp;Mercedes Rigla ,&nbsp;Assumpta Caixàs","doi":"10.1016/j.endien.2023.12.001","DOIUrl":"https://doi.org/10.1016/j.endien.2023.12.001","url":null,"abstract":"<div><p>Prader–Willi Syndrome (PWS) is the most common genetic cause of obesity, occurring in approximately 1 in 15,000 newborns. It results from the lack of expression of genes on the paternal allele of the chromosomal region 15q-11q13 (65–75% due to type 1 or type 2 deletion). Individuals with PWS experience associated symptoms such as hypotonia, hyperphagia, and early-onset obesity (before 5 years of age). Around 20% of adults with PWS also develop type 2 diabetes. Previous studies have shown the beneficial effects of GLP1-RA medications, such as exenatide and liraglutide, in treating type 2 diabetes in PWS. However, there is limited information available on the use of semaglutide in PWS. This study aimed to evaluate the effects of semaglutide on weight loss and glycaemic control in four patients with PWS and type 2 diabetes associated with obesity. The patients were started on weekly subcutaneous progressive doses of semaglutide.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 2","pages":"Pages 83-87"},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140296674","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of the COVID-19 pandemic on gestational diabetes in Castilla-La Mancha (Spain)","authors":"Dulce M.ª Calderón Vicente ,&nbsp;Amparo Marco Martínez ,&nbsp;Inés Gómez García ,&nbsp;Rosa Quílez Toboso ,&nbsp;Iván Quiroga López ,&nbsp;Manolo Delgado Rey ,&nbsp;Javier Gargallo Vaamonde ,&nbsp;María Olmos Alemán ,&nbsp;Raquel Miralles Moragrega ,&nbsp;César Gonzalvo Díaz ,&nbsp;Javier González López ,&nbsp;on behalf of the SCAMEND Group for the Study of Gestational Diabetes during the COVID-19 pandemic","doi":"10.1016/j.endien.2024.03.005","DOIUrl":"10.1016/j.endien.2024.03.005","url":null,"abstract":"<div><h3>Subject-matter</h3><p>To assess the effect of the 2019 coronavirus (COVID-19) pandemic on gestational diabetes (GDM).</p></div><div><h3>Material and methods</h3><p>In this retrospective, multicentre, non-interventional study carried out in Castilla-La Mancha, Spain, we compared 663 women with GDM exposed to the pandemic (pandemic group), with 622 women with GDM seen one year earlier (pre-pandemic group). The primary endpoint was a Large for Gestational Age (LGA) newborn as an indicator of poor GDM control. Secondary endpoints included obstetric and neonatal complications.</p></div><div><h3>Results</h3><p>During the pandemic, the gestational week at diagnosis (24.2 ± 7.4 vs 22.9 ± 7.7, p = 0.0016) and first visit to Endocrinology (26.6 ± 7.2 vs 25.3 ± 7.6, p = 0.0014) were earlier. Face-to-face consultations were maintained in most cases (80.3%). The new diagnostic criteria for GDM were used in only 3% of cases. However, in the pandemic group, the final HbA1c was higher (5.2 ± 0.48 vs 5.29 ± 0.44%, p = 0.047) and there were more LGA newborns (8.5% vs 12.8%, p = 0.015). There were no differences in perinatal complications.</p></div><div><h3>Conclusions</h3><p>Care for GDM in our Public Health System did not significantly deteriorate during the COVID-19 pandemic. However, this did not prevent a higher number of LGA newborns.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 2","pages":"Pages 53-60"},"PeriodicalIF":1.9,"publicationDate":"2024-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140140925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Undergraduate and postgraduate training in Endocrinology and Nutrition","authors":"Pedro José Pinés Corrales","doi":"10.1016/j.endien.2024.01.001","DOIUrl":"10.1016/j.endien.2024.01.001","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 1","pages":"Pages 1-3"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of serum placenta-specific gene 8 protein, total antioxidant capacity, interleukin-10, interleukin-17A, interleukin-21 and interleukin-33 levels in Turkish women with gestational diabetes mellitus","authors":"Enver Ciraci ,&nbsp;Tugba Elgun ,&nbsp;Asiye Gok Yurttas ,&nbsp;Hazel Cagin Kuzey ,&nbsp;Yagmur Ekenoglu Merdan ,&nbsp;Muhammed Sait Toprak ,&nbsp;Sermin Tetik","doi":"10.1016/j.endien.2024.02.002","DOIUrl":"https://doi.org/10.1016/j.endien.2024.02.002","url":null,"abstract":"<div><h3>Purpose</h3><p>Gestational diabetes mellitus (GDM) is defined as carbohydrate intolerance that begins or is diagnosed during pregnancy. Our study aimed to establish a correlation between proinflammatory and anti-inflammatory response in order to be able to develop treatment strategies and determine early diagnosis biomarkers in the sera of cases diagnosed with GDM. Moreover, we aimed to investigate interleukin (IL), placenta-specific gene 8 protein (PLAC8) and total antioxidant capacity (TAC) in patients with GDM.</p></div><div><h3>Methods</h3><p>A total of 121 patients were included in the study. These were divided into four patient groups: pregnant and diagnosed with DM (P-GDM, <em>n</em> <!-->=<!--> <!-->30); pregnant and not diagnosed with DM (P-NGDM, <em>n</em> <!-->=<!--> <!-->32); non-pregnant diagnosed with DM (NP-DM, <em>n</em> <!-->=<!--> <!-->29) and non-pregnant and not diagnosed with DM (NPNDM, <em>n</em> <!-->=<!--> <!-->30). IL-10, IL-17A, IL-21, IL-33, PLAC8 and TAC determinations from patients were evaluated by ELISA (Enzyme-Linked ImmunoSorbent Assay) method.</p></div><div><h3>Results</h3><p>IL-10 and IL-33 concentrations were found to be significantly higher in P-GDM and NP-DM patient groups compared to P-NGDM and NP-NDM groups (<em>p</em> <!-->&lt;<!--> <!-->0.001). The PLAC8 level in the P-GDM patient group (20.38<!--> <!-->±<!--> <!-->5.37) was determined to be significantly higher than in the P-NGDM patient group (3.41<!--> <!-->±<!--> <!-->2.17, <em>p</em> <!-->&lt;<!--> <!-->0.001). TAC in the P-NGDM and NP-NDM groups (12.42<!--> <!-->±<!--> <!-->2.31 vs. 12.96<!--> <!-->±<!--> <!-->3.78, <em>p</em> <!-->&lt;<!--> <!-->0.001) was determined to be significantly higher than in the P-GDM and NP-DM groups (4.8<!--> <!-->±<!--> <!-->0.52 vs. 2.21<!--> <!-->±<!--> <!-->0.71, <em>p</em> <!-->&lt;<!--> <!-->0.001).</p></div><div><h3>Discussion</h3><p>The fact that the importance of PLAC8 level and TAC in the diagnosis and follow-up of GDM in pregnancy is demonstrated for the first time in this study shows that it is unique.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 1","pages":"Pages 12-18"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139908506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Concern about hypoglycaemia is mainly nocturnal: An infodemiology study","authors":"Tomás González-Vidal ,&nbsp;Elías Delgado Álvarez ,&nbsp;Edelmiro Menéndez Torre","doi":"10.1016/j.endien.2024.02.003","DOIUrl":"https://doi.org/10.1016/j.endien.2024.02.003","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 1","pages":"Pages 32-35"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139908507","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Routine consumption of iodized salt in a sample of patients with thyroid nodules","authors":"Estefanía Chumbiauca ,&nbsp;Juan C. Galofré","doi":"10.1016/j.endien.2024.01.005","DOIUrl":"10.1016/j.endien.2024.01.005","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 1","pages":"Pages 38-39"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708278","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypercalcemia as the first finding of late recurrence of a PTHrP neuroendocrine tumor of the pancreas","authors":"Beatriz Febrero ,&nbsp;Beatriz Gómez ,&nbsp;Juan José Ruiz-Manzanera ,&nbsp;Inmaculada Ros-Madrid ,&nbsp;José M. Rodríguez","doi":"10.1016/j.endien.2024.01.002","DOIUrl":"10.1016/j.endien.2024.01.002","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 1","pages":"Pages 31-32"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139730788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carotid pseudoaneurysms after endoscopic transsphenoidal surgery for acromegaly","authors":"Catalina Vivancos Sánchez ,&nbsp;Pedro Navia Álvarez ,&nbsp;Carolina Alfonso Carrillo ,&nbsp;Paola Parra Ramírez ,&nbsp;Carlos Pérez López","doi":"10.1016/j.endien.2024.01.004","DOIUrl":"10.1016/j.endien.2024.01.004","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 1","pages":"Pages 35-37"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139703788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of the efficacy of probiotics as treatment in irritable bowel syndrome","authors":"Cristina Ruiz-Sánchez,&nbsp;Blanca Escudero-López,&nbsp;María-Soledad Fernández-Pachón","doi":"10.1016/j.endien.2024.01.003","DOIUrl":"10.1016/j.endien.2024.01.003","url":null,"abstract":"<div><p>Irritable bowel syndrome (IBS) is a gastrointestinal functional disorder mainly characterised by abdominal pain, bloating and altered bowel habits. Dysbiosis might seem to be involved in the pathogenesis of the disease. Probiotics represent a potential treatment, since these could favour the functional microbiota and improve symptoms. The aim was to review the effectiveness of the use of probiotics in IBS symptomatology, analysing the influence of duration and dose. 18 articles were included. At the individual level, <em>Lactobacillus, Bifidobacterium</em> and <em>Bacillus</em> could be useful in the treatment of symptoms. <em>Bifidobacterium bifidum</em> reported the best results (1 × 10⁹ CFU/day for 4 weeks). The most effective combination was 2 <em>Lactobacillus</em> strains, one of <em>Bifidobacterium</em> and one of <em>Streptococcus</em> (4 × 10⁹ CFU/day for 4 weeks). Future clinical trials should confirm these results and analyse the difference between individual and combined treatments.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 1","pages":"Pages 19-30"},"PeriodicalIF":1.9,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2530018024000039/pdfft?md5=6378cfbf6737fa4eb193548ad5fcbd06&pid=1-s2.0-S2530018024000039-main.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139708277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}