Endocrinologia Diabetes Y Nutricion最新文献

{"title":"Evaluation of plasma cortisol during fasting test in patients with endogenous hyperinsulinemic hypoglycemia. Fifteen years experience","authors":"María Eugenia Gullace ,&nbsp;María Victoria Ortuño ,&nbsp;Teresa Mabel Canteros ,&nbsp;Belén Bosco ,&nbsp;Cintia Rodriguez ,&nbsp;Javier Giunta ,&nbsp;Lucas Costa ,&nbsp;Andrea Kozak ,&nbsp;Valeria de Miguel ,&nbsp;Luis Grosembacher","doi":"10.1016/j.endien.2023.11.008","DOIUrl":"10.1016/j.endien.2023.11.008","url":null,"abstract":"<div><h3>Background</h3><p><span>Endogenous hyperinsulinemic hypoglycemia<span> (EHH) is a rare clinical condition. The aim of this study was to evaluate baseline plasma cortisol concentration and its concentration during </span></span>hypoglycemic crisis in fasting tests (FT) performed in our center. Secondarily, the aim was to establish the relationship between baseline cortisol and the time of evolution of EHH.</p></div><div><h3>Material and methods</h3><p>A retrospective, observational, descriptive study was carried out which included patients with hypoglycemic disorder with positive FT.</p></div><div><h3>Results</h3><p><span>Of a total of 21 patients, 16 presented insulinoma, 1 nesidioblastosis, 2 malignant insulinoma and 2 EHH without pathological diagnosis. The time from the onset of symptoms to diagnosis was 2 years (Q1</span> <!-->=<!--> <!-->1.5–Q2<!--> <!-->=<!--> <!-->5.5). The comparison between median baseline cortisol (BC)<!--> <!-->=<!--> <!-->11.8 mcg/dl (nmol/L 340.68) (Q1<!--> <!-->=<!--> <!-->9–Q3<!--> <!-->=<!--> <!-->14.1) and median cortisol during hypoglycemic episode (HC)<!--> <!-->=<!--> <!-->11.6 mcg/dl (nmol/L: 303.44) (Q1<!--> <!-->=<!--> <!-->7.8–Q3<!--> <!-->=<!--> <!-->16.1) showed no differences (Z<!--> <!-->=<!--> <!-->−0.08; <em>P</em> <!-->&gt;<!--> <!-->.05). When correlating BC with HC, no significant relationship was observed (r<!--> <!-->=<!--> <!-->0.16; <em>P</em> <!-->&gt;<!--> <span>.05). When correlating the glycemic value in the crisis and the HC, a slight negative trend was found (r</span> <!-->=<!--> <!-->−0.53; <em>P</em> <!-->=<!--> <!-->.01). In addition, we found that recurrent hypoglycemic disorder is associated with lower baseline cortisol values ​​the longer the time of its evolution.</p></div><div><h3>Conclusion</h3><p>We confirmed that cortisol values ​​remain low during hypoglycemic episodes, reinforcing the hypothesis of lack of response of this counterregulatory hormone in cases of recurrent hypoglycemia.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 10","pages":"Pages 634-639"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138452860","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Post-transplant diabetes mellitus: Findings in nutritional status and body composition","authors":"Laura Pereira Barretto,&nbsp;Patrícia Moreira Gomes,&nbsp;Natália Rossin Guidorizzi,&nbsp;Miguel Moyses Neto,&nbsp;Elen Almeida Romao,&nbsp;Paula Garcia Chiarello","doi":"10.1016/j.endien.2023.10.005","DOIUrl":"https://doi.org/10.1016/j.endien.2023.10.005","url":null,"abstract":"<div><h3>Introduction</h3><p><span>Weight gain and changes in body composition are associated with the onset of diabetes after kidney transplantation, and detailing these changes can help prevent this situation. The study aimed to assess the prevalence of diabetes mellitus after kidney transplantation and changes in the nutritional status and body composition </span>in patients with diabetes one year from surgery.</p></div><div><h3>Materials and methods</h3><p><span><span>This survey was a single-center, prospective cohort study. Twenty-nine patients over 18 years old who underwent isolated kidney transplantation, without diabetes, were included and followed up for one year. At hospital discharge after transplantation and one year later, </span>anthropometric (weight, height and abdominal circumference), body composition (electrical bioimpedance), routine biochemical and </span>dietary intake assessments were performed.</p></div><div><h3>Results</h3><p>Most of the patients were male (75%), and the mean age was 48.0<!--> <!-->±<!--> <span>11.8 years old. In the first-year post-surgery 27.6% of patients had DM and the diagnosis was made, on average, 4 months after transplantation. The group with diabetes had, from the beginning to the end of the study, greater weight and body fat, especially abdominal fat. The non-diabetic group, after one year, showed an increase in phase angle, body weight and body masses, more pronounced of fat-free mass, when compared with fat mass gain.</span></p></div><div><h3>Conclusions</h3><p>Both groups showed weight gain, but in the non-diabetic group these changes can be interpreted as an improvement in the nutritional profile<span>. Metabolic abnormalities associated with immunosuppression and eating habits, combination that maintains increased the risk for diabetes for long time, keeping this group with priority in nutritional care.</span></p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 10","pages":"Pages 628-633"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138549520","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Opinion of primary care physicians on the use of continuous glucose monitoring in type 2 diabetes","authors":"Domingo Orozco-Beltrán ,&nbsp;Fernando Alvarez-Guisasola ,&nbsp;Flora López-Simarro ,&nbsp;Carlos Miranda-Fernández-Santos ,&nbsp;Antonio Pérez Pérez","doi":"10.1016/j.endien.2023.11.009","DOIUrl":"10.1016/j.endien.2023.11.009","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 10","pages":"Pages 656-658"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138435264","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Development of hypoglycemia in a patient with type 1 diabetes mellitus: A little-known adverse effect of linezolid","authors":"Raquel Niddam,&nbsp;Fernando Vidal-Ostos de Lara,&nbsp;Jhamil Zurita-Campos,&nbsp;Concepción Blanco-Carrera,&nbsp;Jose Antonio Rubio","doi":"10.1016/j.endien.2023.11.006","DOIUrl":"10.1016/j.endien.2023.11.006","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 10","pages":"Pages 654-656"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138463777","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Normocalcemic hyperparathyroidism after successful parathyroidectomy for single parathyroid adenoma: Prevalence, etiological factors, predictive markers, treatment and evolution","authors":"Luis García Pascual ,&nbsp;Andreu Simó-Servat ,&nbsp;Carlos Puig-Jové ,&nbsp;Lluís García-González","doi":"10.1016/j.endien.2023.11.007","DOIUrl":"10.1016/j.endien.2023.11.007","url":null,"abstract":"<div><h3>Background and objective</h3><p>Postparathyroidectomy normocalcemic hyperparathyroidism<span><span> (PPNCHPPT) is a frequent situation for which we have no information in our country. The objective is to know our prevalence of PPNCHPPT, the associated etiological factors, the predictive markers, the </span>treatment administered and the evolution.</span></p></div><div><h3>Patients and method</h3><p>Retrospective observational cross-sectional study on 42 patients. Twelve patients with PPNCHPPT and 30 without PPNCHPPT are compared.</p></div><div><h3>Results</h3><p><span><span>HPPTNCPP prevalence: 28.6%. Etiological factors: vitamin D<span> deficiency: 75%; bone remineralization: 16.7%; renal failure: 16.7%; hypercalciruria: 8.3%. No change in the set point of calcium-mediated parathormone (PTH) secretion was observed, but an increase in the preoperative PTH/albumin-corrected calcium (ACC) ratio was observed. Predictive markers: PTH/ACC ratio (AUC 0.947; sensitivity 100%, specificity 78.9%) and PTH (AUC 0.914; sensitivity 100%, specificity 73.7%) one week postparathyroidectomy. Evolution: follow-up 30 ± 16.3 months: 50% normalized PTH and 8.3% had recurrence of hyperparathyroidism. Patients with PPNCHPPT less frequently received </span></span>preoperative treatment with </span>bisphosphonates<span> and postoperative treatment with calcium salts.</span></p></div><div><h3>Conclusions</h3><p><span>This is the first study in our country that demonstrates a mean prevalence of PPNCHPPT, mainly related to a vitamin D deficiency and a probable resistance to the action of PTH, which can be predicted by the PTH/ACC ratio and PTH a week post-intervention and often evolves normalizing the PTH. We disagree with the etiological effect of hypercalciuria and the change in the PTH/calcemia regulation set point, and we acknowledge the scant treatment administered with calcium salts in the </span>postoperative period.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 10","pages":"Pages 640-648"},"PeriodicalIF":1.9,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138435263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How do we choose the most appropriate clinical guidelines?","authors":"Mercè Fernández Balsells","doi":"10.1016/j.endien.2023.05.017","DOIUrl":"10.1016/j.endien.2023.05.017","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 9","pages":"Pages 561-563"},"PeriodicalIF":1.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89720045","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Percutaneous ethanol injection in thyroid nodular pathology and metastatic cervical adenopathies: A systematic review, meta-analysis and economic evaluation","authors":"Beatriz León-Salas ,&nbsp;Aránzazu Hernández-Yumar ,&nbsp;Diego Infante-Ventura ,&nbsp;Aythami de Armas Castellano ,&nbsp;Yadira González Hernández ,&nbsp;Renata Linertová ,&nbsp;Teresa Téllez Santana ,&nbsp;Pedro de Pablos-Velasco ,&nbsp;María M. Trujillo-Martín","doi":"10.1016/j.endien.2023.08.007","DOIUrl":"10.1016/j.endien.2023.08.007","url":null,"abstract":"<div><h3>Background</h3><p>Percutaneous ethanol injection (PEI) has been shown to be a valuable treatment for thyroid nodular pathology and metastatic cervical adenopathies.</p></div><div><h3>Objective</h3><p>To evaluate the effectiveness, safety, and cost-effectiveness of PEI in thyroid nodular pathology and metastatic cervical adenopathies.</p></div><div><h3>Methods</h3><p>A systematic review (SR) using meta-analysis was conducted on the effectiveness and safety of PEI. A SR on cost-effectiveness was also performed. The SRs were conducted according to the methodology developed by the Cochrane Collaboration with reporting in accordance with the PRISMA statement. A cost-minimization analysis was carried out using a decision tree model. Assuming equal effectiveness between two minimally invasive techniques (PEI and radiofrequency ablation (RFA)), the model compared the costs of the alternatives with a horizon of six months and from the perspective of the Spanish National Health System.</p></div><div><h3>Results</h3><p>The search identified three RCTs (<em>n</em> <!-->=<!--> <!-->157) that evaluated PEI versus RFA in patients diagnosed with benign thyroid nodules: ninety-six patients with predominantly cystic nodules and sixty-one patients with solid nodules. No evidence was found on other techniques or thyroid nodular pathology. No statistically significant differences were observed between PEI and RFA in volume reduction (%), symptom score, cosmetic score, therapeutic success and major complications. No economic evaluations were identified. The cost-minimization analysis estimated the cost per patient of the PEI procedure at €326 compared to €4781 for RFA, which means an incremental difference of −€4455.</p></div><div><h3>Conclusions</h3><p>There are no differences between PEI and RFA regarding their safety and effectiveness, but the economic evaluation determined that the former option is cheaper.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 9","pages":"Pages 572-583"},"PeriodicalIF":1.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypopituitarism after traumatic brain injury in adults: Clinical guidelines of the neuroendocrinology area of the Spanish Society of Endocrinology and Nutrition (SEEN)","authors":"Eva Fernández Rodriguez ,&nbsp;Rocío Villar Taibo ,&nbsp;Ignacio Bernabeu","doi":"10.1016/j.endien.2023.11.002","DOIUrl":"10.1016/j.endien.2023.11.002","url":null,"abstract":"<div><p><span><span><span>Traumatic brain injury<span> (TBI) is associated with hypopituitarism with a variable incidence, depending on the time and methods used to diagnosis, and on factors related to the trauma, such as its severity, its anatomical location and the </span></span>drugs<span> used in the acute phase. The pituitary gland<span><span> can be damaged directly by the impact or secondary to factors such as ischemia, inflammation, </span>excitotoxicity or immunity. In acute phases </span></span></span>ACTH<span> deficiency is the most relevant, since failure to detect and treat it can compromise the patient's life. Clinical manifestations are typical of each hormone deficient axes, although the combination hypopituitarism-trauma has been associated with cognitive deterioration, worse metabolic profile and greater impairment of </span></span>quality of life. One of the clinical challenges is to determine which patients benefit from a systematic hormonal evaluation, and therefore from hormone replacement, and what is the appropriate time to do so and the most suitable diagnostic methods.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 9","pages":"Pages 584-591"},"PeriodicalIF":1.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136399902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"How to handle HMG-CoA lyase deficiency and type 1 diabetes? A challenging case report","authors":"André Morais ,&nbsp;Teresa Pinheiro ,&nbsp;Ana Sofia Figueiredo ,&nbsp;Cíntia Castro Correia ,&nbsp;Teresa Campos ,&nbsp;Esmeralda Rodrigues ,&nbsp;Elisa Leão Teles","doi":"10.1016/j.endien.2023.11.004","DOIUrl":"10.1016/j.endien.2023.11.004","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 9","pages":"Pages 609-611"},"PeriodicalIF":1.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Adult female with severe decompensation of tyrosinaemia type 1 that responds to heme treatment","authors":"Elena Casademunt-Gras ,&nbsp;Analia Ramos ,&nbsp;Sabina Ruiz ,&nbsp;Mariona Martin ,&nbsp;Clara Joaquín","doi":"10.1016/j.endien.2023.07.005","DOIUrl":"10.1016/j.endien.2023.07.005","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"70 9","pages":"Pages 612-613"},"PeriodicalIF":1.9,"publicationDate":"2023-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138300397","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}