Endocrinologia Diabetes Y Nutricion最新文献

{"title":"Corrigendum to: Impact of oral semaglutide on quality of life and metabolic parameters in patients with type 2 diabetes mellitus: A multicenter observational study","authors":"","doi":"10.1016/j.endien.2026.501844","DOIUrl":"10.1016/j.endien.2026.501844","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 8","pages":"Article 501844"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149175466","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"What primary care can contribute to screening for type 1 diabetes","authors":"Miguel Ángel María Tablado","doi":"10.1016/j.endien.2026.501946","DOIUrl":"10.1016/j.endien.2026.501946","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 8","pages":"Article 501946"},"PeriodicalIF":1.9,"publicationDate":"2026-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149175465","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Behavior change techniques to improve treatment adherence in type 2 diabetes: A systematic review","authors":"Ana Rosa Villalpando-Gutiérrez,&nbsp;Héctor Velázquez-Jurado,&nbsp;Carolina Palacios-Burguete,&nbsp;Karla Paola Colin-Mendiola,&nbsp;Julián Grostieta Dominguez,&nbsp;Ana Cristina García-Ulloa,&nbsp;Liliana Pérez-Peralta","doi":"10.1016/j.endien.2026.501774","DOIUrl":"10.1016/j.endien.2026.501774","url":null,"abstract":"<div><h3>Introduction</h3><div>Cognitive-behavioral interventions have shown positive results in type 2 diabetes mellitus (T2DM) self-management; however, the lack of detailed descriptions of these interventions makes their replication difficult. This study aims to identify behavioral change techniques (BCT) for improving adherence to medication, diet, and exercise in adults with T2DM.</div></div><div><h3>Method</h3><div>We conducted a systematic search in June 2024 across PubMed, Cochrane, Web of Science, PsycINFO, and CINAHL to identify studies published since 2013 that examined BCTs aimed at improving treatment adherence in adults with T2DM.</div></div><div><h3>Results</h3><div>A total of 6 articles – including randomized controlled trials, a scoping review, and systematic reviews – were included, addressing adherence to medication, diet, and exercise. BCTs associated with improved adherence and reported across multiple studies included action planning (1.4), social support (unspecified) (3.1), social support (practical) (3.2), instruction on how to perform a behavior (4.1), information about health consequences (5.1), prompts and cues (7.1), and credible source (9.1).</div></div><div><h3>Conclusions</h3><div>The findings highlight the importance of clearly structured intervention descriptions and the use of robust theoretical frameworks. Future interventions should incorporate components targeting patient education, skill development, and support networks to enhance adherence to dietary recommendations, physical activity, and pharmacological treatment.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501774"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Knowledge and management of metabolic dysfunction-associated steatotic liver disease among endocrinologists in Spain","authors":"María Teresa Julián,&nbsp;Miguel A. Rubio-Herrera,&nbsp;Javier Escalada,&nbsp;Núria Alonso,&nbsp;on behalf of the MASLD Working Group of the Spanish Society of Endocrinology and Nutritition","doi":"10.1016/j.endien.2026.501846","DOIUrl":"10.1016/j.endien.2026.501846","url":null,"abstract":"<div><h3>Background</h3><div>Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent chronic liver disease and is closely associated with type 2 diabetes mellitus (T2DM) and obesity. However, it continues to have limited clinical visibility outside the field of Hepatology.</div></div><div><h3>Objective</h3><div>To evaluate knowledge, liver fibrosis screening practices, and perceived barriers related to MASLD among endocrinologists in Spain.</div></div><div><h3>Materials and methods</h3><div>An exploratory cross-sectional observational study was conducted using an online survey promoted by the MASLD Working Group of the Spanish Society of Endocrinology and Nutrition (SEEN) and addressed to all society members. A total of 210 anonymized surveys were analyzed, collecting information on: liver fibrosis screening in patients with T2DM and/or obesity, diagnostic tools used, availability of clinical protocols, access to liver elastography, and the main barriers to MASLD management. A descriptive analysis of the results was performed.</div></div><div><h3>Results</h3><div>Approximately half of the endocrinologists reported performing liver fibrosis screening in patients with T2DM or obesity. FIB-4 was the most frequently used screening tool (78.4%), although automated calculation was available in only 60.8% of centers. Lack of time, insufficient training, and limited protocol availability (31.6%) were identified as the main barriers, and direct access to elastography from Endocrinology departments was limited.</div></div><div><h3>Conclusions</h3><div>This exploratory study shows that MASLD is not yet fully integrated into endocrinology practice in Spain. The lack of systematic screening, together with organisational and educational barriers, limits the early detection of hepatic fibrosis in high-risk populations. Strengthening awareness, training, and protocol development is necessary to integrate liver health into the comprehensive management of patients with metabolic disease.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501846"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148450046","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Hypothalamic–pituitary axis MRI findings in pediatric endocrine disorders: A retrospective study","authors":"Angela Domínguez-García,&nbsp;David Navarro-Domínguez,&nbsp;Sofía Quinteiro-González,&nbsp;Sara López-López,&nbsp;María F. Cabrera-Guedes,&nbsp;Yeray Nóvoa-Medina","doi":"10.1016/j.endien.2026.501781","DOIUrl":"10.1016/j.endien.2026.501781","url":null,"abstract":"<div><h3>Background</h3><div>Magnetic resonance imaging (MRI) of the hypothalamic–pituitary axis (HPA) is widely used in pediatric endocrinology, yet the clinical relevance of structural abnormalities remains debated.</div></div><div><h3>Objective</h3><div>To assess the diagnostic yield of HPA MRI in children with endocrine disorders and identify clinical/hormonal predictors of clinically relevant findings.</div></div><div><h3>Methods</h3><div>We retrospectively analysed a total of 202 patients (1 month to 17 years) evaluated from 2018 through 2023 for suspected HPA dysfunction. Diagnostic groups included isolated growth hormone deficiency (IGHD), multiple pituitary hormone deficiency (MPHD), short stature without growth hormone deficiency (SSWGD), central precocious puberty (CPP), central diabetes insipidus (CDI), and pituitary hypersecretion syndrome (PHS). MRI findings were classified as normal, relevant, or incidental. Logistic regression and ROC analysis were used to identify predictive factors.</div></div><div><h3>Results</h3><div>Abnormal MRI findings were identified in 29.2% of patients (59/202); 14.9% (30/202) were clinically relevant and 14.4% (29/202), incidental. Diagnostic yield (any abnormal finding) was highest in MPHD (100%) and CDI (87.5%), followed by PHS (40.0%), SSWGD (30.8%), CPP (26.4%) and IGHD (23.2%). In IGHD, lower GH peaks on the exercise–propranolol test were significantly associated with abnormal MRI findings (OR, 3.98; 95%CI, 1.53–10.30; <em>P</em> <!-->=<!--> <!-->.026). There were no predictors for CPP. Incidental lesions were most common in CPP and IGHD.</div></div><div><h3>Conclusions</h3><div>MRI showed the highest diagnostic yield in MPHD and CDI. In IGHD, lower GH peak values may help guide selective imaging, while in CPP the lack of reliable predictors supports routine MRI. Multidisciplinary interpretation remains essential to contextualise incidental findings.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501781"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961730","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reflection on the need for type 1 prediabetes screening: one year after publication of the Spanish consensus","authors":"M. Rigla Cros,&nbsp;M.M. Fernández Balsells,&nbsp;A.M. Wägner","doi":"10.1016/j.endien.2026.501877","DOIUrl":"10.1016/j.endien.2026.501877","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501877"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Estimated vascular age using the Framingham model as a predictor of metabolic syndrome in a large cohort of Spanish workers","authors":"Natalia Montero Muñoz,&nbsp;Pedro Juan Tárraga López,&nbsp;Irene Coll Campayo,&nbsp;Ángel Arturo López-González,&nbsp;Carla Busquets-Cortés,&nbsp;José Ignacio Ramírez-Manent","doi":"10.1016/j.endien.2026.501773","DOIUrl":"10.1016/j.endien.2026.501773","url":null,"abstract":"<div><h3>Background</h3><div>Vascular age, estimated using the Framingham model, is an intuitive indicator of cardiovascular risk. Metabolic syndrome (MetS) includes several cardiometabolic abnormalities associated with increased morbidity and mortality. The relationship between vascular age and MetS has not been extensively assessed in large working populations.</div></div><div><h3>Objective</h3><div>To evaluate the predictive ability of vascular age for identifying MetS in a large cohort of Spanish workers.</div></div><div><h3>Methods</h3><div>We conducted a cross-sectional study among 336,450 employees aged 18–69 years who underwent standardized occupational health examinations from 2018 to 2022. Vascular age and avoidable lost life years (ALLY) were calculated using the Framingham equation. MetS was defined according to NCEP ATP III, IDF, and Joint Interim Statement (JIS) criteria. Associations were examined using logistic regression models adjusted for sociodemographic and lifestyle variables. Discriminatory performance was assessed through ROC curve analyses.</div></div><div><h3>Results</h3><div>MetS prevalence increased progressively across higher vascular age categories in both sexes. Vascular age demonstrated strong diagnostic performance, with areas under the curve<!--> <!-->&gt;<!--> <!-->0.80 and reaching 0.86 in women according to NCEP ATP III and JIS definitions. Multivariable analyses confirmed independent associations between elevated vascular age and MetS.</div></div><div><h3>Conclusions</h3><div>Vascular age is a strong and consistent predictor of MetS and represents a practical tool for early cardiometabolic risk detection in occupational settings. Its integration into workplace health surveillance may enhance the identification of high-risk workers and support targeted preventive strategies.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501773"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary central nervous system lymphoma involving the hypothalamic–pituitary axis presenting with hypopituitarism: A case report with long-term follow-up","authors":"David Sanchis-Pascual,&nbsp;Rosa Cámara Gómez,&nbsp;Pilar Morillas-Amat,&nbsp;Samuel Romero Domínguez,&nbsp;Joan Carreres-Polo,&nbsp;Darío Lara-Gálvez,&nbsp;Lucía Cano-Jiménez,&nbsp;Juan Díaz Nohales,&nbsp;Juan Francisco Merino-Torres","doi":"10.1016/j.endien.2026.501798","DOIUrl":"10.1016/j.endien.2026.501798","url":null,"abstract":"<div><div>Primary central nervous system lymphoma (PCNSL) involving the hypothalamic–pituitary axis is a rare condition and may present with nonspecific neurologic and endocrine signs, often mimicking more common sellar lesions. We report the case of a 59-year-old woman admitted with subacute behavioral changes, cognitive decline, and polyuria. Magnetic resonance imaging revealed a pituitary–infundibular mass with suprasellar extension and marked bifrontal edema. Endocrine evaluation demonstrated panhypopituitarism and arginine vasopressin deficiency. The clinical course was complicated by severe dysnatremias requiring intensive care management and hormonal replacement. Histopathologic analysis of a transsphenoidal biopsy confirmed diffuse large B-cell lymphoma, with no systemic disease on PET-CT or bone marrow evaluation. The patient was treated with the MATRix chemotherapy regimen followed by autologous stem cell transplantation, achieving sustained complete remission at 3.5 years. Persistent hypogonadotropic hypogonadism remained as a sequelae. This case underscores the diagnostic challenges of sellar involvement by PCNSL and highlights the importance of including lymphoma in the differential diagnosis of hypothalamic–pituitary masses. Acute pituitary failure with severe electrolyte disturbances may precede oncologic diagnosis, and early multidisciplinary management combined with aggressive therapy can result in long-term remission.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501798"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Executive summary of the Integrated Clinical care pathway for the detection and management of preclinical stages of type 1 diabetes: SED-SEEN-SEEP consensus","authors":"Ana Lucía Gómez Gila,&nbsp;Fernando Gómez-Peralta,&nbsp;Susana Pica Montesinos,&nbsp;Virginia Bellido,&nbsp;Roque Cardona-Hernandez,&nbsp;María Asunción Martínez-Brocca","doi":"10.1016/j.endien.2026.501879","DOIUrl":"10.1016/j.endien.2026.501879","url":null,"abstract":"<div><div>Type 1 diabetes (T1D) can be identified in preclinical stages through the detection of islet autoantibodies and staged before clinical onset. This evolving paradigm highlights the need for structured care models allowing coordinated identification, staging, and follow-up of individuals with positive islet autoimmunity. This document describes an Integrated Care Pathway (ICP) developed from the available scientific evidence and the national SED-SEEN-SEEP consensus on screening and monitoring of preclinical T1D. The model is organised into three core sub-processes (target population identification, autoantibody detection and confirmation, and clinical follow-up with staging) and one transversal support sub-process based on information systems and performance indicators. This ICP provides a structured, evaluable, and scalable framework for the homogeneous implementation of screening and follow-up of preclinical T1D.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501879"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921413","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Methodological considerations in defining incident overweight and obesity in EHR-based cohorts: A comment on Breton et al.","authors":"Ankur Sharma,&nbsp;Varshini Vadhithala,&nbsp;Arun Kumar,&nbsp;Sushma Verma,&nbsp;Sushma Narsing Katkuri","doi":"10.1016/j.endien.2026.501782","DOIUrl":"10.1016/j.endien.2026.501782","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"73 7","pages":"Article 501782"},"PeriodicalIF":1.9,"publicationDate":"2026-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148961726","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}