Endocrinologia Diabetes Y Nutricion最新文献

{"title":"Chrononutrition patterns and their association with body weight: Differences across multiple chronotypes","authors":"Giovana Longo-Silva ,&nbsp;Renan Serenini ,&nbsp;Anny Pedrosa ,&nbsp;Márcia Lima ,&nbsp;Larissa Soares ,&nbsp;Júlia Melo ,&nbsp;Risia Menezes","doi":"10.1016/j.endien.2024.12.006","DOIUrl":"10.1016/j.endien.2024.12.006","url":null,"abstract":"<div><h3>Introduction</h3><div>In recent years, the focus of research on obesity and its management has expanded beyond traditional dietary factors to include the timing of food intake – in relation to the body's circadian rhythms – known as chrononutrition. However, chrononutrition patterns remain largely unexplored in low-medium income countries. Our study aimed to investigate the association between chrononutrition patterns and BMI.</div></div><div><h3>Material and methods</h3><div>Utilizing data from the virtual Survey SONAR-Brazil (<em>n</em> <!-->=<!--> <!-->2137,18–65 y), we defined the following chrononutrition patterns: 1. The clock time of the first, mid, and last eating events; 2. Morning and evening latencies (from wake-up time until the first eating event, and from the last eating event until bedtime); and 3. Eating window. Linear regression analyses assessed associations between chrononutrition variables and BMI. Quantile regression and restricted cubic splines were used to explore distributional correlations and association shapes.</div></div><div><h3>Results</h3><div>Among all participants, BMI increased with each additional hour of the first eating event (<em>β</em> <!-->=<!--> <!-->0.17; 95% CI, 0.05,0.29; <em>P</em> <!-->=<!--> <!-->0.005), morning latency (<em>β</em> <!-->=<!--> <!-->0.27; 95% CI, 0.12,0.42; <em>P</em> <!-->&lt;<!--> <!-->0.001), and eating midpoint (<em>β</em> <!-->=<!--> <!-->0.21; 95% CI, 0.05,0.38; <em>P</em> <!-->=<!--> <!-->0.01) and the effect was even stronger with higher BMI percentiles. There was no effect of eating times among intermediate and late chronotypes. However, among early types, positive associations were seen between the BMI and the timing of the first eating event, morning latency, and eating midpoint, as well as a negative association with evening eating.</div></div><div><h3>Conclusions</h3><div>Our findings suggest that delaying the first eating event, the eating midpoint, and extending morning latency are associated with higher BMI, particularly in early chronotypes. These results highlight the importance of aligning eating patterns with chronotypes and support personalized dietary recommendations.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 1","pages":"Pages 4-13"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"When anorexia nervosa complicates: Bezoar and gastroduodenal obstruction","authors":"Vanessa Capristán-Díaz ,&nbsp;Pablo de Sol ,&nbsp;Juan González González ,&nbsp;Rosalía González Miyar ,&nbsp;Rocío Campos del Portillo","doi":"10.1016/j.endien.2024.12.002","DOIUrl":"10.1016/j.endien.2024.12.002","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 1","pages":"Pages 50-51"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142899364","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of vitamin D supplementation on TSH and thyroid hormones: A systematic review of randomized controlled trials","authors":"Sara Safari ,&nbsp;Sara Shojaei-Zarghani ,&nbsp;Roghayeh Molani-Gol ,&nbsp;Maryam Rafraf ,&nbsp;Mahsa Malekian","doi":"10.1016/j.endien.2024.12.007","DOIUrl":"10.1016/j.endien.2024.12.007","url":null,"abstract":"<div><h3>Objective</h3><div>Approximately 200 million people have been diagnosed with thyroid disease worldwide. Associations between thyroid disorders and nutritional factors have been established in former studies.</div></div><div><h3>Methods</h3><div>The Web of Science, PubMed, and Scopus databases and Google Scholar were searched without date restriction until June 2023 by using relevant keywords. All original articles written in English that studied the effects of vitamin D supplementation on TSH and thyroid hormones were eligible for the present review.</div></div><div><h3>Results</h3><div>The present review included a total of 16 randomized controlled trials (RCTs) with 1127 participants (intervention group, 630; control group, 497). Based on the findings made, vitamin D supplementation had no significant effects on serum TSH levels in 9 cases (56.2%) reported in the trials. However, TSH levels were elevated in 4 studies (26.6%) and low in 3 (18.7%) cases after vitamin D administration. Four cases reported in 6 RCTs and 4 cases reported in 5 trials indicated no significant effects on thyroxine (T₄) and triiodothyronine (T₃) levels after vitamin D supplementation, respectively. Moreover, 8 cases of 11 included RCTs reported that vitamin D intake had no significant effects on fT4, and 5 cases of 7 RCTs demonstrated no significant effects on fT3 levels after vitamin D supplementation.</div></div><div><h3>Conclusion</h3><div>Most findings suggest that vitamin D supplementation had no significant effects on thyroid hormones and more than half indicated no significant effect on TSH levels. Nevertheless, high-quality research is further required to prove these achievements and evaluate vitamin D effects on other markers of thyroid function.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 1","pages":"Pages 37-46"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966788","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Reducing hyperuricemic events with SGLT2 inhibitors: An updated systematic review with meta-regression","authors":"Hamlet Ghukasyan ,&nbsp;Denilsa Dinis Pedro Navalha ,&nbsp;Ignacio Pérez Romero ,&nbsp;Maria Vitória Prato Wolwacz ,&nbsp;Artur Ghahramanyan ,&nbsp;Cristiane Wen Tsing Ngan ,&nbsp;Maria Helena Siqueira Tavares de Melo ,&nbsp;Caroline Serafim Dagostin ,&nbsp;Luis Gómez-Lechón Quirós","doi":"10.1016/j.endien.2024.12.005","DOIUrl":"10.1016/j.endien.2024.12.005","url":null,"abstract":"<div><h3>Introduction</h3><div>Although sodium-glucose cotransporter-2 inhibitors (SGLT2i) were shown to lower hyperuricemic events in patients with type 2 diabetes mellitus (T2DM), the extent of this effect in the general population is yet to be elucidated. We performed an updated systematic review and meta-analysis on a large sample of patients with and without T2DM to evaluate the influence of SGLT2i therapy on clinically relevant hyperuricemic events, defined as the composite of acute gout flare episodes, acute anti-gout management or urate-lowering therapy initiation. Furthermore, we conducted a multivariate meta-regression to assess the relationship between different covariates and the pooled effect size.</div></div><div><h3>Materials and methods</h3><div>We systematically searched all reported outcomes of interest in patients on SGLT2i (PROSPERO: CRD42023442077) across PubMed, Scopus and Cochrane databases looking for randomized controlled trials, observational studies and post-hoc analyses since inception until August 2023.</div></div><div><h3>Results</h3><div>Data from seven randomized controlled trials and seven observational studies were included for a total of 464,009 patients, 13,370 of whom did not have T2DM. A total of 50% of the patients included were on SGLT2i. The pooled analysis demonstrated that SGLT2i reduce clinically relevant hyperuricemic events by 33% (HR, 0.67; 95% CI, 0.59–0.77; <em>I</em>² <!-->=<!--> <!-->83%) regardless of the concomitant diagnosis of T2DM. The multivariate meta-regression on chronic kidney disease (CKD) showed a positive correlation on the pooled effect size.</div></div><div><h3>Conclusions</h3><div>SGLT2i reduce the risk of developing hyperuricemic events regardless of the concomitant diagnosis of T2DM. The multivariate meta-regression on CKD showed a significant impact on the main outcome. Further studies are essential to investigate more conclusively the extent of these beneficial effects.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 1","pages":"Pages 26-36"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142966789","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Rhinocerebral mucormycosis: an uncommon complication in patients with diabetes mellitus","authors":"Sara Rodríguez Arboleya ,&nbsp;Lucía Díaz Naya ,&nbsp;Raquel Fernández Morais ,&nbsp;María Sagrario Santos Seoane ,&nbsp;María Pasarón Fernández","doi":"10.1016/j.endien.2024.12.003","DOIUrl":"10.1016/j.endien.2024.12.003","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"72 1","pages":"Pages 51-53"},"PeriodicalIF":1.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142911026","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Phase angle: Differences between disease-related malnutrition, obesity and healthy people","authors":"Mario A. Saavedra Vásquez ,&nbsp;Javier Castañón Alonso ,&nbsp;Begoña Pintor de la Maza ,&nbsp;Elena González Arnáiz ,&nbsp;Diana García Sastre ,&nbsp;Diana G. Ariadel Cobo ,&nbsp;Ana M. Urioste Fondo ,&nbsp;María Antequera González ,&nbsp;María del Carmen Dameto Pons ,&nbsp;María D. Ballesteros Pomar","doi":"10.1016/j.endien.2024.07.003","DOIUrl":"10.1016/j.endien.2024.07.003","url":null,"abstract":"<div><h3>Introduction</h3><div>Bioelectrical Impedance Analysis (BIA) is a tool used in clinical nutrition and pure electrical data such as phase angle (PA) has shown prognostic value. It relates resistance and reactance indicating cellular health.</div></div><div><h3>Objective</h3><div>To determine differences in PA between patients with obesity and disease-related malnutrition (DRM) compared to the healthy population, and to establish associations between PA and other body composition (BC) parameters.</div></div><div><h3>Materials and methods</h3><div>Retrospective observational study with 1079 patients from the Obesity and Nutrition Department of the Complejo Asistencial Universitario de León between April/2014 and August/2022 as well as 86 healthy controls. Demographic and anthropometric variables were collected and BC was performed with BIA Tanita MC780®. Diagnosis of malnutrition according to GLIM criteria and obesity with body mass index (BMI).</div></div><div><h3>Results</h3><div>PA50KHz in obesity group is 5.98º, DRM 4.79º and control group 6.08º. Statistically significant differences in PA between DRM and control groups, as well as DRM and obesity (<em>p</em> &lt; 0.001). Weak positive correlation in total population (<em>r</em> = 0.452, <em>p</em> &lt; 0.001) as well as control group (<em>r</em> = 0.463, <em>p</em> &lt; 0.001) between BMI and PA. Weak negative correlation in the total population (<em>r</em> = −0.408, <em>p</em> &lt; 0.001), DRM (<em>r</em> = −0.268, <em>p</em> &lt; 0.001) and obesity (<em>r</em> = −0.342, <em>p</em> &lt; 0.001) between age and PA.</div></div><div><h3>Conclusions</h3><div>In this study, significantly lower PA was observed in the DRM group than in the control and obesity groups. No statistically significant differences between PA in the obesity and control groups and no correlation between BMI and PA in the obesity group. More studies are needed to standardize cut-off points in different contexts and populations.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 10","pages":"Pages 421-426"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682848","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Micro solutions for macro problems: Challenging thyroid and parathyroid function tests","authors":"Utku Soyaltin ,&nbsp;Ayla Yildiz ,&nbsp;Nurhilal Yusufoğlu ,&nbsp;Emre İspir","doi":"10.1016/j.endien.2024.11.013","DOIUrl":"10.1016/j.endien.2024.11.013","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 10","pages":"Pages 456-458"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Super response to liraglutide in people with obesity: A case report and literature review","authors":"Sonsoles Gutiérrez Medina ,&nbsp;Elena Sánchez Campayo ,&nbsp;Sonsoles Guadalix ,&nbsp;Javier Escalada","doi":"10.1016/j.endien.2024.11.012","DOIUrl":"10.1016/j.endien.2024.11.012","url":null,"abstract":"<div><div>GLP1 receptor agonists (GLP1-RAs) are currently the most widely used pharmacological option to treat obesity. However, considerable heterogeneity in weight loss response has been observed with different anti-obesity drugs and response predictors to these drugs still remain ambiguous. Furthermore, very few published data have been available on cases of high-responders to treatment with GLP1-RAs. In this article, we present the case of a patient with grade 4 obesity (initial body mass index, 50.2<!--> <!-->kg/m²) with associated mechanical and metabolic complications who achieved an initial weight loss of 40% at 1 year with hygienic-dietary measures and drug treatment with liraglutide. We also review the available literature on factors potentially contributing to variations in weight loss with GLP1-RAs in general and liraglutide, in particular.</div></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 10","pages":"Pages 447-453"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142745754","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Are we underdiagnosing cognitive impairment in patients with type 2 diabetes mellitus?","authors":"Antelm Pujol ,&nbsp;Pilar Sanchis ,&nbsp;María I. Tamayo ,&nbsp;Lluís Masmiquel","doi":"10.1016/j.endien.2024.11.009","DOIUrl":"10.1016/j.endien.2024.11.009","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 10","pages":"Pages 454-455"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142682840","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Thyroid and assisted reproduction","authors":"Gemma Sesmilo","doi":"10.1016/j.endien.2024.10.002","DOIUrl":"10.1016/j.endien.2024.10.002","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 10","pages":"Pages 411-414"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142740786","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}