Endocrinologia Diabetes Y Nutricion最新文献

{"title":"New approaches to refractory necrobiosis lipoidica with photodynamic therapy: Case report","authors":"A. López Montalbán , A. López Ávila","doi":"10.1016/j.endien.2024.05.002","DOIUrl":"10.1016/j.endien.2024.05.002","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 6","pages":"Pages 271-273"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581176","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effect of coffee intake on appetite parameters in woman with overweight or obesity: A pilot crossover randomized trial","authors":"Lisset Magaña-de la Vega ,&nbsp;Erika Martínez-López ,&nbsp;Tania Sanchez-Murguia ,&nbsp;Andrea Madrigal-Juárez ,&nbsp;Saraí Citlalic Rodríguez-Reyes ,&nbsp;Ivan Aguilar-Vega ,&nbsp;Nathaly Torres-Castillo","doi":"10.1016/j.endien.2024.03.021","DOIUrl":"10.1016/j.endien.2024.03.021","url":null,"abstract":"<div><h3>Introduction</h3><p>Coffee consumption has demonstrated an effect on the regulation of appetite, causing less hunger and/or greater satiety; however, its effects are not well known in woman with overweight or obesity. Therefore, this study aimed to evaluate the effect of coffee consumption on hunger, satiety, sensory specific desire (SSD), and dietary intake in women with overweight or obesity.</p></div><div><h3>Methodology</h3><p>A randomized crossover clinical trial was realized in 3 sessions: in the first session a clinical history, anthropometric measurements and body composition analysis were performed; in sessions 2 and 3 the participants randomly consumed 240<!--> <!-->mL of coffee with 6<!--> <!-->mg/caffeine/kg of weight or 240<!--> <!-->mL of water along with a standardized breakfast. At fasting and every 30<!--> <!-->min after breakfast for the next 3<!--> <!-->h, appetite sensations and SSD were recorded using visual analog scales. Blood samples were taken at fasting, 30 and 180<!--> <!-->min after breakfast. Dietary intake was recorded in the rest of the intervention days.</p></div><div><h3>Results</h3><p>In the coffee intervention there was an increased desire for sweet foods, higher fructose intake during the rest of the day, and higher triglyceride levels than with the water intervention. No differences were detected in ghrelin or cholecystokinin.</p></div><div><h3>Conclusions</h3><p>Coffee consumption may lead to higher triglycerides and higher intake of simple sugars, mainly fructose, through changes in the SSD.</p><p>Clinical Trial Registration: <span>https://clinicaltrials.gov/</span><svg><path></path></svg> <span>NCT05774119</span><svg><path></path></svg>.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 6","pages":"Pages 236-245"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581175","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of socioeconomic factors on glycemic control, therapeutic adherence and quality of life in children and adolescents with type 1 diabetes","authors":"Carmen Yoldi-Vergara ,&nbsp;Ignacio Conget-Donlo ,&nbsp;Roque Cardona-Hernandez ,&nbsp;Marta Ramon-Krauel","doi":"10.1016/j.endien.2024.04.003","DOIUrl":"10.1016/j.endien.2024.04.003","url":null,"abstract":"<div><h3>Objective</h3><p>To stablish the relationship between socioeconomic status of a cohort of children and adolescents with type 1 diabetes (T1D) with glycemic control, therapeutic adherence and diabetes quality of life (DQoL).</p></div><div><h3>Patients y methods</h3><p>A cross-sectional, observational study with consecutive inclusion was carried out. Participants aged 8–18 years with T1D duration &gt;1 year. Data on family structure, family income, parents’ educational level and parental role on primary diabetes care supervision were registered. Adherence (DMQ-Sp) and DQoL (PedsQl) were analyzed. Linear and logistic regression models adjusted for demographics, family structure and parental role on primary diabetes care responsibility were applied.</p></div><div><h3>Results</h3><p>A total of 323 patients (T1D duration 5,3 ± 3,3 years; HbA1c 7,7 ± 1,0%; age 13,3 ± 2,8 years; 49,8% females) were included. Patients living in a nuclear family and those whose main diabetes care supervision was shared by both parents showed lower HbA1c [adjusted for demographics and family structure (7,06; CI 95% 6,52–7,59); adjusted for demographics and role on primary diabetes care supervision (7,43; CI 95% 6,57–8,28)]. DMQ-Sp score (adjusted for demographics and role on main supervision) was higher in patients whose parents shared the diabetes care supervision (84,56; CI 95% 73,93–95,19). Parents sharing diabetes care supervision showed a significantly higher PedsQl score (both 74,63 ± 12,70 vs mother 68,53 ± 14,59; p = 0,001).</p></div><div><h3>Conclusions</h3><p>Children and adolescents with T1D had lower HbA1c, better therapeutic adherence and better DQoL when lived in a nuclear family, with higher socioeconomic status and the responsibility for supervising diabetes care was shared by both parents.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 6","pages":"Pages 253-262"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141471747","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Serum cholesterol levels are inversely associated with the risk of malignancy in subjects with Bethesda category IV thyroid nodules","authors":"Beatriz Montejo-Marcos ,&nbsp;Yaiza López-Plasencia ,&nbsp;Dunia Marrero-Arencibia ,&nbsp;Carlos A. Rodríguez-Pérez ,&nbsp;Mauro Boronat","doi":"10.1016/j.endien.2024.03.022","DOIUrl":"10.1016/j.endien.2024.03.022","url":null,"abstract":"<div><h3>Introduction</h3><p>Some epidemiological data suggest that there may be an inverse relationship between cholesterol levels and the risk of thyroid cancer in the overall population. The present study was aimed to evaluate the lipid profile specifically in subjects with Bethesda category IV thyroid nodules, and compare whether there were any differences between those with benign and malignant nodules.</p></div><div><h3>Methods</h3><p>Single-centre, retrospective study on 204 subjects treated by partial or total thyroidectomy for excision of a Bethesda category IV thyroid nodule, who had undergone a blood lipid profile test in the 12 months prior to surgery. In addition to lipid measures, other demographic, clinical, biochemical and ultrasound data were collected.</p></div><div><h3>Results</h3><p>Seventy-five subjects (36.8%) were diagnosed with thyroid carcinoma in the definitive histopathological examination. Patients with thyroid cancer had lower levels of total cholesterol, LDL-cholesterol and non-HDL-cholesterol than subjects with benign thyroid diseases. There were no differences in HDL-cholesterol, triglycerides or total cholesterol/HDL-cholesterol ratio. There were no differences either between groups in other clinical, biochemical and ultrasound variables, including the use of lipid-lowering drugs. In multivariate analysis, only LDL-cholesterol was independently associated with malignancy. Subjects with follicular carcinoma showed the lowest cholesterol levels, while those with papillary carcinoma had intermediate values between the group with follicular carcinoma and the group with benign thyroid diseases.</p></div><div><h3>Conclusions</h3><p>In subjects with cytologically indeterminate Bethesda category IV thyroid nodules, levels of total cholesterol, non-HDL-cholesterol and, particularly, LDL-cholesterol are lower among those with malignant nodules.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 6","pages":"Pages 246-252"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581177","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Personalized medicine in type 1 diabetes: The influence of socioeconomic context","authors":"Fernando Sebastian-Valles","doi":"10.1016/j.endien.2024.05.001","DOIUrl":"10.1016/j.endien.2024.05.001","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 6","pages":"Pages 227-228"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141444119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Carcinoid crisis: The challenge is still there","authors":"Fernando Guerrero-Pérez ,&nbsp;Inmaculada Peiró ,&nbsp;José L. Vercher-Conejero ,&nbsp;Alex Teulé ,&nbsp;Carles Villabona","doi":"10.1016/j.endien.2024.03.020","DOIUrl":"10.1016/j.endien.2024.03.020","url":null,"abstract":"<div><p>Carcinoid crisis (CC) has classically been considered the extreme end of the spectrum of carcinoid syndrome (CS). However, this presumption and other aspects of CC remain poorly understood. Consequently, current clinical guidelines are based on a low quality of evidence. There is no standard definition of CC and its incidence is unknown. Patients with florid CS and elevated serotonin (or its derivatives) which develop CC have been reported during decades. Nevertheless, the hypothesis that CC is due to the sudden massive release of serotonin or other vasoactive substances is unproven. Many triggers of CC (surgery, anaesthesia, peptide receptor radionuclide therapy, tumour biopsy or liver-directed treatments) have been proposed. However, data from studies are heterogeneous and even contradictory. Finally, the role of octreotide in the prevention of CC has been questioned. Herein, we report a clinical case and perform a critical review of the evidence available today on this topic.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 6","pages":"Pages 263-270"},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141581174","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Risk factors for hypoglycaemia in non-critical hospitalised diabetic patients","authors":"Diego Valero Garzón ,&nbsp;Santiago Forero Saldarriaga ,&nbsp;Ana Milena Robayo Batancourt ,&nbsp;José David Puerta Rojas ,&nbsp;Valentina Aranguren Pardo ,&nbsp;Lina Paola Fajardo Latorre ,&nbsp;Milciades Ibañez Pinilla","doi":"10.1016/j.endien.2024.02.006","DOIUrl":"10.1016/j.endien.2024.02.006","url":null,"abstract":"<div><h3>Objective</h3><p>To determine the risk factors for hypoglycaemia in patients with diabetes on general hospital wards based on a systematic review of the literature since 2013 and meta-analysis.</p></div><div><h3>Methods</h3><p>Systematic review of the literature focused on the conceptual and methodological aspects of the PRISMA Declaration. The search carried out in Pub Med, Web of Science, Medline, Scielo, Lilacs, OVID, grey literature and Google Academic focused on risk factors for hypoglycaemia in patients with diabetes on general hospital wards. The CASPe (Critical Appraisal Skills Programme Spanish) tool was applied for quality control.</p></div><div><h3>Results</h3><p>From 805 references, 70 potentially eligible articles were identified for review of abstracts and full text. Finally, according to inclusion and exclusion criteria, seven studies with 554,601 patients of Asian, European and North American ethnicity were selected.</p><p>A meta-analysis performed using the random effects model found an association between the presence of hypoglycaemia and: the use of insulin (OR 2.89 [95% CI: 1.8−4.5]); the use of long-acting insulin (OR 2.27 [95% CI: 1.8−2.8]) or fast-acting insulin (OR 1.4 [95% CI: 1.18−1.85]); nasogastric tube feeding (OR 1.75 [95% CI: 1.33−2.3]); chronic kidney disease (OR 1.65 [95% CI: 1.14−2.38]); congestive heart failure (OR 1.36 [95% CI: 1.10−1.68]); and elevated levels of glycosylated haemoglobin (OR 1.59 [95% CI: 1.32−1.91]).</p></div><div><h3>Conclusion</h3><p>The factors associated with the risk of hypoglycaemia in non-critically ill hospitalised patients with type 2 diabetes were: use of any insulin; nasogastric tube feeding; elevated glycosylated haemoglobin levels; history of congestive heart failure; and chronic kidney disease.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 5","pages":"Pages 194-201"},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141293847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Use of electronic health records for the management of diabetes and its risk factors in the Principality of Asturias from 2014 to 2018","authors":"Miguel García-Villarino ,&nbsp;Carmen Lambert ,&nbsp;Jesús M. De la Hera ,&nbsp;Edelmiro Luis Menéndez Torre ,&nbsp;José María Fernández Rodríguez-Lacín ,&nbsp;Elías Delgado-Álvarez","doi":"10.1016/j.endien.2024.03.017","DOIUrl":"https://doi.org/10.1016/j.endien.2024.03.017","url":null,"abstract":"<div><h3>Background</h3><p>In recent years, the implementation of electronic health records across all hospitals and primary care centres within the National Health System has significantly enhanced access to patients’ clinical data. This study aims to estimate the prevalence of type 2 diabetes (T2DM) in primary care settings and to outline its associated cardiovascular risk factors (CVRF) and epidemiological characteristics.</p></div><div><h3>Methods</h3><p>An observational cross-sectional study was conducted including 89,679 patients diagnosed with T2DM who attended the primary health care system from 2014 to 2018. Data was provided by the Primary Health Care System of the Principality of Asturias (SESPA).</p></div><div><h3>Results</h3><p>The estimated prevalence of diagnosed T2DM was 8.01% (95% Confidence Interval [CI]: 7.96–8.06) of the total population. Additionally, it was more prevalent in males compared to females (9.90% [95% CI: 9.81–9.99] vs. 6.50% [95% CI: 6.44–6.57]) and increased with age in both sexes. People with T2DM had an average age of 74 years, 52.3% were male, and the most frequently associated CVRF were: dyslipidaemia (47.90%) and hypertension (62.20%). Glycaemic control improved during the 2014–2018 period (31.69%), as did lipid control (23.66%). However, the improvement in blood pressure control (9.34%) was less pronounced for the same period. Regarding the multifactorial control of diabetes (measured by LDL-cholesterol, HbA1C and blood pressure) the overall degree of control improved by 11.55% between 2014 and 2018.</p></div><div><h3>Conclusion</h3><p>In this 5-year retrospective population-based study, the utilisation of data from electronic medical records provides insights into the prevalence of T2DM in a large population, as well as real-time CVRFs. Leveraging this data facilitates the development of targeted health policies.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 5","pages":"Pages 208-215"},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141423774","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The importance of MLPA technique in the diagnosis of multiple endocrine neoplasia type 1","authors":"Antonio Bustos-Merlo,&nbsp;Carlos Javier García Calvente,&nbsp;Antonio Rosales-Castillo","doi":"10.1016/j.endien.2024.02.004","DOIUrl":"10.1016/j.endien.2024.02.004","url":null,"abstract":"","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 5","pages":"Pages 223-225"},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141288794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Influence of obesity on blood glucose control using continuous glucose monitoring data among patients with type 1 diabetes","authors":"Joana Nicolau,&nbsp;Andrea Romano,&nbsp;Irene Rodríguez,&nbsp;Pilar Sanchís,&nbsp;María Puga,&nbsp;Lluís Masmiquel","doi":"10.1016/j.endien.2024.02.007","DOIUrl":"https://doi.org/10.1016/j.endien.2024.02.007","url":null,"abstract":"<div><h3>Introduction</h3><p>The global increase in the prevalence rates of overweight or obesity has also affected patients with type 1 diabetes (T1D), where this disease had traditionally been associated with a lean phenotype. On the other hand, the effect of obesity on new glycemic control metrics obtained from continuous glucose monitoring (CGM) in T1D is poorly understood. We wanted to assess whether there is any relationship between BMI (body mass index) and the different CGM metrics or HbA1c.</p></div><div><h3>Methods</h3><p>Two hundred and twenty-five patients with T1D (47.1% ♀, mean age 42.9<!--> <!-->±<!--> <!-->14.7 years) with a CGM for a minimum of 6 months were analysed by downloading their CGM and collecting clinical and anthropometric variables.</p></div><div><h3>Results</h3><p>35.1% (79/225) of the T1D patients had overweight and 17.3% (39/225) lived with obesity, while the remaining 47.6% had a normal weight. A negative correlation was found between GMI (glucose management indicator) and BMI (−0.2; <em>p</em> <!-->=<!--> <!-->0.008) and HbA1c (−0.2; <em>p</em> <!-->=<!--> <!-->0.01). In contrast, a positive correlation was observed between the total dose of insulin and the BMI (0.3; <em>p</em> <!-->&lt;<!--> <!-->0.0001). No significant correlations were found between BMI and other CGM metrics.</p></div><div><h3>Conclusions</h3><p>Overweight or obesity do not imply worse glycemic control in patients with T1D or less use of CGM. Possibly, and in order to achieve a good glycemic control, more units of insulin are necessary in these patients which, in turn, makes weight control more difficult.</p></div>","PeriodicalId":48650,"journal":{"name":"Endocrinologia Diabetes Y Nutricion","volume":"71 5","pages":"Pages 202-207"},"PeriodicalIF":1.9,"publicationDate":"2024-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141423776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}