Biology-Basel最新文献

{"title":"Comprehensive Review and Assessment of Computational Methods for Prediction of N6-Methyladenosine Sites.","authors":"Zhengtao Luo, Liyi Yu, Zhaochun Xu, Kening Liu, Lichuan Gu","doi":"10.3390/biology13100777","DOIUrl":"https://doi.org/10.3390/biology13100777","url":null,"abstract":"<p><p>N6-methyladenosine (m⁶A) plays a crucial regulatory role in the control of cellular functions and gene expression. Recent advances in sequencing techniques for transcriptome-wide m⁶A mapping have accelerated the accumulation of m⁶A site information at a single-nucleotide level, providing more high-confidence training data to develop computational approaches for m⁶A site prediction. However, it is still a major challenge to precisely predict m⁶A sites using in silico approaches. To advance the computational support for m⁶A site identification, here, we curated 13 up-to-date benchmark datasets from nine different species (i.e., <i>H. sapiens</i>, <i>M. musculus</i>, <i>Rat</i>, <i>S. cerevisiae</i>, <i>Zebrafish</i>, <i>A. thaliana</i>, <i>Pig</i>, <i>Rhesus</i>, and <i>Chimpanzee</i>). This will assist the research community in conducting an unbiased evaluation of alternative approaches and support future research on m⁶A modification. We revisited 52 computational approaches published since 2015 for m⁶A site identification, including 30 traditional machine learning-based, 14 deep learning-based, and 8 ensemble learning-based methods. We comprehensively reviewed these computational approaches in terms of their training datasets, calculated features, computational methodologies, performance evaluation strategy, and webserver/software usability. Using these benchmark datasets, we benchmarked nine predictors with available online websites or stand-alone software and assessed their prediction performance. We found that deep learning and traditional machine learning approaches generally outperformed scoring function-based approaches. In summary, the curated benchmark dataset repository and the systematic assessment in this study serve to inform the design and implementation of state-of-the-art computational approaches for m⁶A identification and facilitate more rigorous comparisons of new methods in the future.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11504118/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510917","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"<i>Quercus glauca</i> Acorn Seed Coat Extract Promotes Wound Re-Epithelialization by Facilitating Fibroblast Migration and Inhibiting Dermal Inflammation.","authors":"Shin-Hye Kim, Hye-Lim Shin, Tae Hyun Son, So-An Lim, Dongsoo Kim, Jun-Hyuck Yoon, Hyunmo Choi, Hwan-Gyu Kim, Sik-Won Choi","doi":"10.3390/biology13100775","DOIUrl":"https://doi.org/10.3390/biology13100775","url":null,"abstract":"<p><p>The skin, recognized as the largest organ in the human body, serves a vital function in safeguarding against external threats. Severe damage to the skin can pose significant risks to human health. There is an urgent requirement for safe and effective therapies for wound healing. While phytotherapy has been widely utilized for various health conditions, the potential of <i>Quercus glauca</i> in promoting wound healing has not been thoroughly explored. <i>Q. glauca</i> is a cultivated crop known for its abundance of bioactive compounds. This study examined the wound-healing properties of <i>Quercus glauca</i> acorn seed coat water extract (QGASE). The findings from the study suggest that QGASE promotes wound closure in HF cells by upregulating essential markers related to the wound-healing process. Additionally, QGASE demonstrates antioxidant effects, mitigating oxidative stress and aiding in recovery from injuries induced by H₂O₂. In vivo experiments provide additional substantiation supporting the efficacy of QGASE in enhancing wound healing. The collective results indicate that QGASE may be a promising candidate for the development of innovative therapeutic strategies aimed at enhancing skin wound repair.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11505045/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Translating Lupus: Comparative Transcriptional Profiles of Preclinical Lupus Models and Their Relevance to Human Disease.","authors":"James T Parker, Ching-Yun Chang, Kara Kersjes, Ixavier A Higgins, Andrew C Vendel, William Y Chang","doi":"10.3390/biology13100778","DOIUrl":"https://doi.org/10.3390/biology13100778","url":null,"abstract":"<p><p>Systemic lupus erythematosus (SLE) is a chronic, systemic autoimmune disease which can present with mixed organ involvement. Kidney involvement in lupus nephritis (LN) is a severe complication and major cause of mortality in SLE patients, second only to cardiovascular disease. While mouse models have helped uncover some molecular pathways involved in SLE/LN, we need a better understanding of the connection of these pathways and the immune cells involved in disease pathogenesis to develop new and effective therapies. Furthermore, models used for studying SLE/LN in mice have a heterogeneous immune response and may not always represent disease manifestations observed in patients. Identifying models that have shared pathways with human disease would allow for better translation for developing effective SLE/LN therapies. The molecular pathways of five different SLE/LN models (MRL/lpr, poly (I:C)-induced, interferon-α-induced, bm12 GvHD, and spontaneous NZB/W F1) were compared to characterize the immune response in mouse kidneys. These models demonstrated varied magnitudes in immune responses and proportions of innate vs. adaptive cell involvement. These findings were compared to human molecular pathways and cell types from public databases, including the Accelerating Medicine Partnership-Systemic Lupus Erythematosus Program (AMP-SLE), to help corelate mechanisms involved in mouse models to human disease.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11505302/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Effects of Extended Treatment with <i>Protium heptaphyllum</i> Liposomes on Metabolic Parameters of Obese Rats.","authors":"Naiéle Sartori Patias, Sara Vieira Maia, Yasmin Gabriele Ferreira, Natalhya Letícia Ferreira de Oliveira, Stela Regina Ferrarini, Gisele Facholi Bomfim, Adilson Paulo Sinhorin, Danilo Henrique Aguiar, Eveline Aparecida Isquierdo Fonseca de Queiroz, Valéria Dornelles Gindri Sinhorin","doi":"10.3390/biology13100771","DOIUrl":"https://doi.org/10.3390/biology13100771","url":null,"abstract":"<p><p><i>Protium heptaphyllum</i> (<i>P. heptaphyllum</i>), popularly known as \"almacega\" or \"white pitch\", is widely used in folk medicine due to its antioxidant, anti-inflammatory and healing properties, attributed to its richness in flavonoids and terpenes. Therefore, this study aimed to evaluate the effects of treatment for 28 days with liposomes containing <i>P. heptaphyllum</i> leaf extract in obese animals. Male Wistar rats, subjected to a hypercaloric diet for 8 weeks to induce obesity (hypercaloric chow and water enriched with 30% sucrose, ad libitum), were treated with the plant formulation (1 mg kg^-1day^-1, via gavage) for 28 days. The study investigated morphological, metabolic, redox state, immunological and histological parameters in adipose and liver tissue. Rats were divided into four groups: control (C), liposomes with extract (H), obese (O) and obese treated with liposomes containing extract (OH). The results indicated that the obese group (O) presented weight gain, hepatic steatosis and alterations in metabolic and inflammatory parameters. However, treatment with liposomes (OH) reduced glucose, alanine aminotransferase (ALT), aspartate aminotransferase (AST), alkaline phosphatase (ALP), creatinine and the lipid profile. In adipose tissue, the OH group showed decreased superoxide dismutase (SOD) activity and increased glutathione S-transferase (GST) activity, in contrast to the effects observed in liver GST. In the analysis of thiobarbituric-acid-reactive substances (TBARS), it was possible to observe an increase in all groups in adipose tissue and in group O in liver tissue, in addition to a reduction in TBARS in group OH in the liver, indicating modulation of oxidative stress. The treatment also increased the concentration of IL-10 and IL-17 in the liver and decreased that of IL-6 in adipose tissue. After 28 days of treatment, these results point to the therapeutic potential of treatment with <i>P. heptaphyllum</i>, not necessarily only against obesity, but also an effect per se of the liposomes, possibly due to the high concentration of flavonoids present in the plant extract.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11505265/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510929","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Bioactive Peptides from Corn (<i>Zea mays</i> L.) with the Potential to Decrease the Risk of Developing Non-Communicable Chronic Diseases: In Silico Evaluation.","authors":"Caroline Cagnin, Bianca de Fátima Garcia, Thais de Souza Rocha, Sandra Helena Prudencio","doi":"10.3390/biology13100772","DOIUrl":"https://doi.org/10.3390/biology13100772","url":null,"abstract":"<p><p>Studies have shown that corn (<i>Zea mays</i> L.) proteins, mainly α-zein, have the potential to act on therapeutic targets related to non-communicable chronic diseases, such as high blood pressure and type 2 diabetes. Enzymatic hydrolysis of proteins present in foods can result in a great diversity of peptides with different structures and possible bioactivities. A review of recent scientific research papers was performed to show evidence of the bioactive properties of corn peptides by in vitro assays. The α-zein amino acid sequences were identified in the UniProtKB protein database and then analyzed in the BIOPEP database to simulate enzymatic digestion and verify the potential biological action of the resulting peptides. The peptides found in the BIOPEP database were categorized according to the probability of presenting biological action using the PeptideRanker database. The aim was to use existing data to identify in silico the potential for obtaining biologically active peptides from α-zein, the main storage protein of corn. The analysis showed that the majority of peptide fragments were related to the inhibition of angiotensin-converting enzyme, followed by the inhibition of dipeptidyl peptidase IV and dipeptidyl peptidase III. Many drugs used to treat high blood pressure and type 2 diabetes work by inhibiting these enzymes, suggesting that corn peptides could be potential alternative agents. In vitro studies found that the primary bioactivity observed was antioxidative action. Both in vitro and in silico approaches are valuable for evaluating the bioactive properties resulting from protein hydrolysis, such as those found in α-zein. However, conducting in vitro studies based on prior in silico evaluation can be more efficient and cost-effective.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11505114/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510908","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Catching the Big Fish in Big Data: A Meta-Analysis of Zebrafish Kidney scRNA-Seq Datasets Highlights Conserved Molecular Profiles of Macrophages and Neutrophils in Vertebrates.","authors":"Aleksandr V Bobrovskikh, Ulyana S Zubairova, Ludmila G Naumenko, Alexey V Doroshkov","doi":"10.3390/biology13100773","DOIUrl":"https://doi.org/10.3390/biology13100773","url":null,"abstract":"<p><p>The innate immune system (IIS) is an ancient and essential defense mechanism that protects animals against a wide range of pathogens and diseases. Although extensively studied in mammals, our understanding of the IIS in other taxa remains limited. The zebrafish (<i>Danio rerio</i>) serves as a promising model organism for investigating IIS-related processes, yet the immunogenetics of fish are not fully elucidated. To address this gap, we conducted a meta-analysis of single-cell RNA sequencing (scRNA-seq) datasets from zebrafish kidney marrow, encompassing approximately 250,000 immune cells. Our analysis confirms the presence of key genetic pathways in zebrafish innate immune cells that are similar to those identified in mammals. Zebrafish macrophages specifically express genes encoding cathepsins, major histocompatibility complex class II proteins, integral membrane proteins, and the V-ATPase complex and demonstrate the enrichment of oxidative phosphorylation ferroptosis processes. Neutrophils are characterized by the significant expression of genes encoding actins, cytoskeleton organizing proteins, the Arp2/3 complex, and glycolysis enzymes and have demonstrated their involvement in GnRH and CLR signaling pathways, adherents, and tight junctions. Both macrophages and neutrophils highly express genes of NOD-like receptors, phagosomes, and lysosome pathways and genes involved in apoptosis. Our findings reinforce the idea about the existence of a wide spectrum of immune cell phenotypes in fish since we found only a small number of cells with clear pro- or anti-inflammatory signatures.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11505477/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510909","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Characterization of New <i>Tropicoporus</i> Species (Basidiomycota, Hymenochaetales, Hymenochaetaceae) Discovered in Tamil Nadu, India.","authors":"Elangovan Arumugam, Ramesh Murugadoss, Sugantha Gunaseelan, Samantha C Karunarathna, Abdallah M Elgorban, Pabulo Henrique Rampelotto, Malarvizhi Kaliyaperumal","doi":"10.3390/biology13100770","DOIUrl":"https://doi.org/10.3390/biology13100770","url":null,"abstract":"<p><p>This study aimed to investigate the morphological characteristics and phylogenetic relationships of three new species of <i>Tropicoporus</i> from the southern parts of India. The analyses of the ITS and nLSU regions revealed the novelty of these species, which have been named <i>T. pannaensis</i>, <i>T. subindicus</i>, and <i>T. xerophyticus</i>. All three species possess pileate basidiomes, a monomitic hyphal system in the context, and the presence of cystidioles and setae. However, they differ significantly in their phylogenetic placements and other morpho-taxonomic features. <i>Tropicoporus pannaensis</i> is characterized by a meagrely ungulate basidiome, indistinct zones, and an obtuse margin. <i>Tropicoporus subindicus</i> has a triquetrous basidiome and a radially cracked, crusted pileal surface with an acute margin, while <i>T. xerophyticus</i> is distinguished by an imbricate, perennial basidiome with an abundantly warted pileal surface. A phylogenetic tree is provided to show the placement of the three new species, along with detailed descriptions and illustrations. Additionally, a key for the identification of the Asian species of <i>Tropicoporus</i> is presented.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11504104/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510914","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Unpredictable Repeated Stress in Rainbow Trout (<i>Oncorhynchus mykiss</i>) Shifted the Immune Response against a Fish Parasite.","authors":"Cyril Henard, Hanxi Li, Barbara F Nowak, Louise von Gersdorff Jørgensen","doi":"10.3390/biology13100769","DOIUrl":"https://doi.org/10.3390/biology13100769","url":null,"abstract":"<p><p>Farmed fish are regularly subjected to various stressors due to farming practices, and their effect in the context of a disease outbreak is uncertain. This research evaluated the effects of unpredictable repeated stress in rainbow trout challenged with the ciliate <i>Ichthyophthirius multifiliis</i>, known to cause white spot disease in freshwater fish. Before and after the pathogen exposure, fish were handled with a random rotation of three procedures. At 7 days post-infection (dpi), the parasite burden was evaluated in fish and in the tank's water, and the local and systemic immune responses were investigated in the gill and spleen, respectively. The fish mortality was recorded until 12 dpi, when all the fish from the infected groups died. There was no statistical difference in parasite burden (fish and tank's water) and infection severity between the two infected fish groups. The immune gene expression analysis suggested a differential immune response between the gill and the spleen. In gills, a T helper cell type 2 immune response was initiated, whereas in spleen, a T helper cell type 1 immune response was observed. The stress has induced mainly upregulations of immune genes in the gill (<i>cat-1</i>, <i>hep</i>, <i>il-10</i>) and downregulations in the spleen (<i>il-2</i>, <i>il-4</i>/<i>13a</i>, <i>il-8</i>). Our results suggested that the unpredictable repeated stress protocol employed did not impair the fish immune system.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11504028/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Involvement of Endoplasmic Reticulum Stress during the Interaction between Calcium Oxalate Crystals and Renal Tubular Epithelial Cells.","authors":"Sen-Yuan Hong, Lin-Tao Miao, Bao-Long Qin","doi":"10.3390/biology13100774","DOIUrl":"https://doi.org/10.3390/biology13100774","url":null,"abstract":"<p><p>Our study aimed to elucidate the mechanisms behind the interaction between calcium oxalate (CaOx) crystals and renal tubular epithelial cells through transcriptome sequencing analysis. HK-2 cells were stimulated with or without CaOx monohydrate crystals and subjected to RNA-seq to assess the effects of CaOx crystals on gene expression changes, key pathways, and molecular players during this interaction. A total of 629 differentially expressed genes (DEGs) were identified between the control group and experimental group, with 491 genes up-regulated and 138 down-regulated. Functional enrichment analysis indicated that the DEGs were significantly associated with endoplasmic reticulum stress (ERS) and unfolded protein response. To validate our findings, we compared our results with the public dataset GSE73680 and confirmed the increased expression of two ERS-related DEGs, CHAC1 and FGF21, in renal papillary tissues from patients with CaOx stones. Collectively, these findings suggest that ERS plays a crucial role in the crystal-cell interaction and highlight the potential for developing therapeutic strategies aimed at reducing CaOx stone formation by targeting ERS-related molecules and pathways.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11504059/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510897","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Distribution and Ecological Risk of <i>Ludwigia peploides</i> in South Korea.","authors":"Aram Jo, Soo In Lee, Donghui Choi, Youngha Kim, Yong Ho Lee, Sun Hee Hong","doi":"10.3390/biology13100768","DOIUrl":"https://doi.org/10.3390/biology13100768","url":null,"abstract":"<p><p>The number of alien species introduced into South Korea continues to increase over the years. In particular, several plants have been introduced as ornamentals. <i>Ludwigia peploides</i>, which is native to the Americas and Australia, is believed to have been planted as an ornamental aquatic plant called \"water primrose\" and \"primrose\". It spread to natural ecosystems through rivers, and its distribution is gradually expanding in Suwon, Hwaseong, Busan, and Jeju. However, there has been no specific study on the ecological risk of <i>L. peploides</i> introduced into South Korea. This study, therefore, investigates the distribution status and ecological risks of <i>L. peploides</i> in South Korea through field surveys and allelopathic material analysis, as well as assessing abiotic risk factors. The distribution was confirmed at a total of 19 sites, with high-density mats of a single species forming along the water's edge and on the water surface. The maximum distribution area was 13,922 m² in Chilgok Reservoir in Anseong. Stems and plant fragments transported along waterways were continuously forming colonies through vegetative propagation. When evaluating the overall risk, it is determined that <i>L. peploides</i> has a high potential to cause significant damage to the ecosystem if not managed promptly. Therefore, continuous monitoring is necessary to effectively manage and prevent the habitat expansion of <i>L. peploides</i>. The results of this study are expected to aid in the identification of the current distribution and potential ecological risks of <i>L. peploides</i> in South Korea, providing essential data for ecological risk assessment and the development of effective management strategies.</p>","PeriodicalId":48624,"journal":{"name":"Biology-Basel","volume":"13 10","pages":""},"PeriodicalIF":3.6,"publicationDate":"2024-09-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11504348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510924","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":3,"RegionCategory":"生物学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}