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Assessing the Importance of Spatial Scale in Climate-Health Models: The Effect of Temperature on Emergency Department Visits in Richmond, Virginia 评估气候-健康模型中空间尺度的重要性:温度对弗吉尼亚州里士满急诊就诊的影响。
IF 5 2区 医学
Geohealth Pub Date : 2026-09-09 DOI: 10.1029/2026GH001852
Truc-Ly Le-Huynh, Wendy M. Novicoff, Pamela B. DeGuzman, Robert E. Davis
{"title":"Assessing the Importance of Spatial Scale in Climate-Health Models: The Effect of Temperature on Emergency Department Visits in Richmond, Virginia","authors":"Truc-Ly Le-Huynh,&nbsp;Wendy M. Novicoff,&nbsp;Pamela B. DeGuzman,&nbsp;Robert E. Davis","doi":"10.1029/2026GH001852","DOIUrl":"10.1029/2026GH001852","url":null,"abstract":"<p>Climate-health studies often rely on data from a single high-quality weather station to represent the exposure of individuals living in the surrounding region. However, with the availability of various gridded climatic data sets, a critical question is whether spatially explicit data can better capture individual environmental exposures and reveal stronger climate-health associations. We investigated the impact of spatial-scale climatic variability and representativeness for emergency department (ED) visits in Richmond, Virginia, United States. This study compared the climate-health relationship using data from a weather station and the ERA5 reanalysis from 2016 to 2022. We evaluated the correlation of the two time-series and used generalized additive models to compare the temperature-ED visit associations across four nested spatial scales. The results were highly consistent across all spatial scales. The station and ERA5 data exhibited similar distributions. The temperature-ED visit relationships showed strong agreement between the two data sources, reflected in both location-specific and pooled estimates. Although ERA5 produced slightly lower cold-related and higher heat-related estimates at extreme temperatures, no marked differences were found between the two data sources. Our findings suggest that, in this region with a relatively homogeneous climate, the variations of regional climate might be small enough to fall within the model's expected uncertainty. Although this result may not apply in regions with considerable local climate variation, data from a single high-quality station in many regions are appropriate to model climate-health relationships over the greater surrounding areas. We recommend similar comparative work across diverse climatic settings to evaluate the generalizability of this conclusion.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 9","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13555616/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921436","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Where on Earth Are the Earth Sciences? A Mixed-Methods Study of Environmental Justice Research Trends and Roadblocks to Engagement 地球科学到底在哪里?环境正义的混合方法研究研究趋势和参与的障碍。
IF 5 2区 医学
Geohealth Pub Date : 2026-09-08 DOI: 10.1029/2025GH001799
Omar Rosales Cortez, Catherine Chen
{"title":"Where on Earth Are the Earth Sciences? A Mixed-Methods Study of Environmental Justice Research Trends and Roadblocks to Engagement","authors":"Omar Rosales Cortez,&nbsp;Catherine Chen","doi":"10.1029/2025GH001799","DOIUrl":"10.1029/2025GH001799","url":null,"abstract":"<p>Environmental justice (EJ) research relies on expertise from multiple disciplines to address community-specific health risks and inequities. EJ is an inherently transdisciplinary framework, yet the expansion of EJ scholarship has not occurred evenly across academic disciplines. Understanding disciplinary contributions is essential for identifying gaps in knowledge and practice. This research employed a mixed-method approach to investigate EJ research trends and roadblocks to engagement. Study 1 used a bibliometric analysis of Scopus-indexed publications and found that Environmental science and Social sciences were the leading contributors to EJ scholarship. Earth sciences ranked only seventh in EJ research volume by proportion and exhibited comparatively stagnant growth. Study 2 investigated this discrepancy through a survey of Earth scientists (<i>N</i> = 460) examining perceived barriers to EJ engagement. Results indicated that career stage was a significant predictor of EJ familiarity and community involvement: early-career Earth scientists were more familiar with EJ but were less involved in their communities' environmental issues than their late-career counterparts. Race and ethnicity were also associated with differences in perceived funding difficulty, with White respondents reporting fewer challenges in securing support for EJ-related projects. Taken together, these studies assess EJ engagement within the Earth sciences and identify structural and experiential factors that may limit participation. Identifying disciplinary gaps and roadblocks helps integrate Earth sciences into EJ scholarship and increase research on environmental health and equity.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 9","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-09-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13554993/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148921390","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Maternal Serum Nitrate and Nitrite Associations With Birth Outcomes: A Case-Control Study 母亲血清硝酸盐和亚硝酸盐与分娩结局的关系:一项病例对照研究。
IF 5 2区 医学
Geohealth Pub Date : 2026-09-03 DOI: 10.1029/2026GH001859
Wael K. Al-Delaimy, Omar F. Khabour, Yousef Khader, Fayez A. Abdulla, Hanan Hammouri, Nour Abdo, Razan A. Saleh
{"title":"Maternal Serum Nitrate and Nitrite Associations With Birth Outcomes: A Case-Control Study","authors":"Wael K. Al-Delaimy,&nbsp;Omar F. Khabour,&nbsp;Yousef Khader,&nbsp;Fayez A. Abdulla,&nbsp;Hanan Hammouri,&nbsp;Nour Abdo,&nbsp;Razan A. Saleh","doi":"10.1029/2026GH001859","DOIUrl":"10.1029/2026GH001859","url":null,"abstract":"<p>Nitrate and nitrite contamination of groundwater and surface water is a global public health concern, often linked to the increasing use of nitrogen-based fertilizers. In Jordan's Ghor region, where agriculture is intensive and fertilizer use is widespread, the issue is particularly relevant. This study aimed to investigate the relationship between serum nitrate and nitrite levels with low birth weight and preterm birth. A total of 659 participants were enrolled, comprising 452 controls (normal birth weight and full-term delivery) and 207 cases (low birth weight/preterm delivery). High maternal serum nitrite levels were significantly associated with increased odds of low birth weight delivery in both the unadjusted model (odds ratio [OR] = 1.43, 95% CI: 1.14–1.80, <i>P</i> = 0.002) and the a priori confounder set adjusted model (OR = 1.33, 95% CI: 1.02–1.74, <i>P</i> = 0.038). Nitrite levels were also significantly associated with the combined outcome of preterm and/or low birth weight delivery in the unadjusted model (OR = 1.26, 95% CI: 1.01–1.57, <i>P</i> = 0.036), and this association remained significant after a priori adjustment in a multiple-imputation sensitivity analysis (OR = 1.29, 95% CI: 1.03–1.63, <i>P</i> = 0.029). In conclusion, although metabolically interrelated, nitrite and nitrate levels in pregnant women may differentially impact pregnancy outcomes in the largely low income agricultural communities in the Ghor region in Jordan.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 9","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-09-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13540271/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148888970","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
How Do Climatic Factors Directly Influence the Incidence and Risk of Meningococcal Meningitis Across the African Meningitis Belt? A Narrative Literature Review 气候因素如何直接影响非洲脑膜炎带脑膜炎球菌性脑膜炎的发病率和风险?叙事文学述评
IF 5 2区 医学
Geohealth Pub Date : 2026-08-29 DOI: 10.1029/2025GH001749
Molly Cliff, Kanny Diallo, Richard B. Yapi, Axelle B. D. Tano, Sally Jahn, Caroline M. Wainwright, Caroline Trotter
{"title":"How Do Climatic Factors Directly Influence the Incidence and Risk of Meningococcal Meningitis Across the African Meningitis Belt? A Narrative Literature Review","authors":"Molly Cliff,&nbsp;Kanny Diallo,&nbsp;Richard B. Yapi,&nbsp;Axelle B. D. Tano,&nbsp;Sally Jahn,&nbsp;Caroline M. Wainwright,&nbsp;Caroline Trotter","doi":"10.1029/2025GH001749","DOIUrl":"https://doi.org/10.1029/2025GH001749","url":null,"abstract":"<p>Globally, the highest incidence of meningococcal meningitis occurs within the African meningitis belt, spanning 26 countries across sub-Saharan Africa. Meningococcal meningitis incidence is highly seasonal in this region specifically, with outbreaks mostly occurring during the dry season, characterized by low rainfall and atmospheric humidity, high temperature, and increased dust and wind speed. The strong seasonality of meningococcal outbreaks coincides with seasonal variation in climatic factors. This multicollinearity can make it difficult to identify environmental drivers of disease and the mechanisms by which they operate. This review aims to collate existing evidence to better clarify the mechanisms by which climatic variables influence meningococcal meningitis incidence. We examined the impact of dust, wind speed, temperature, rainfall, and land cover on meningococcal meningitis outbreaks. Within the literature, atmospheric dust and wind speed had the strongest statistical association with meningococcal outbreaks and demonstrated greater predictive probability than other climatic variables. However, several climatic factors have demonstrable influences on one another, reflected in the seasonality of meningococcal meningitis. Atmospheric dust can reduce precipitation levels in part through its radiative properties. Decreased rainfall and increasing temperatures can dry out soil, increasing its availability to be uplifted as dust. Alongside, this lower atmospheric humidity increases evaporative demand, leading to faster soil moisture loss and enhanced surface drying. We argue that rainfall, temperature, and land cover variability may act as part of a broader climatic mechanism, increasing atmospheric dust. This increases the incidence and risk of meningococcal meningitis.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 9","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-08-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2025GH001749","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148849373","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Analysis of Spatiotemporal Risks of Environmental Driving Factors of Respiratory Diseases 呼吸系统疾病环境驱动因素时空风险分析
IF 5 2区 医学
Geohealth Pub Date : 2026-08-25 DOI: 10.1029/2026GH001881
Xu Yang, Junshu Wang, Guoming Zhang, Zhaoyuan Yu
{"title":"Analysis of Spatiotemporal Risks of Environmental Driving Factors of Respiratory Diseases","authors":"Xu Yang,&nbsp;Junshu Wang,&nbsp;Guoming Zhang,&nbsp;Zhaoyuan Yu","doi":"10.1029/2026GH001881","DOIUrl":"10.1029/2026GH001881","url":null,"abstract":"<p>Respiratory diseases pose a serious threat to the health of residents in China and cause enormous socio-economic losses. Jiangsu has a total of over 27 million vulnerable people in two groups: children under 15 years old and the elderly over 65 years old. Therefore, studies on the spatio-temporal risks of respiratory diseases and their influencing factors in Jiangsu Province are of particular importance. Based on the Distributed Lag Nonlinear Model (DLNM) and the Geographically and Temporally Weighted Regression Model (GTWR), this study took the hospitalized cases of respiratory diseases in Jiangsu Province from 2020 to 2023 as research samples. It deeply explored the complex temporal relationships and spatial differences between environmental driving factors and the HRRD (hospitalization rate of respiratory diseases). It quantified the nonlinear relationships and lag effects of environmental driving factors on the HRRD. Additionally, it conducted a quantitative analysis of the specific impacts of each factor on the hospitalization rate under different spatio-temporal conditions. The research results show that there are significant differences in the lag effects of extreme meteorological factors, air pollutants, and comprehensive meteorological factors on respiratory diseases among different age groups. Similarly, the impacts of these factors on the HRRD also exhibit different spatial heterogeneities. This research reveals the spatio-temporal distribution patterns and driving mechanisms of respiratory diseases, offering a scientific foundation for the development of regionalized and differentiated prevention and control strategies.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 8","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-08-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13505196/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148820050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Quantifying Heterogeneous Impacts of Geolocated mHealth Tracing on Spatiotemporal Transmission of Emerging Infections 量化地理定位移动健康追踪对新发感染时空传播的异质影响
IF 5 2区 医学
Geohealth Pub Date : 2026-08-10 DOI: 10.1029/2026GH001838
Zhifeng Cheng, Hao Liang, Fei Gao, Xuyao Chen, Xiao Liu, Yuping Zhou, Xu Chen, Hui Jiang, Samantha Cockings, Andrew Tatem, Shengjie Lai, Chu He
{"title":"Quantifying Heterogeneous Impacts of Geolocated mHealth Tracing on Spatiotemporal Transmission of Emerging Infections","authors":"Zhifeng Cheng,&nbsp;Hao Liang,&nbsp;Fei Gao,&nbsp;Xuyao Chen,&nbsp;Xiao Liu,&nbsp;Yuping Zhou,&nbsp;Xu Chen,&nbsp;Hui Jiang,&nbsp;Samantha Cockings,&nbsp;Andrew Tatem,&nbsp;Shengjie Lai,&nbsp;Chu He","doi":"10.1029/2026GH001838","DOIUrl":"10.1029/2026GH001838","url":null,"abstract":"<p>Digital health tools, including mobile device location-based health (mHealth) applications, have been adopted to augment conventional contact tracing during recent epidemics and pandemics, yet quantitative evidence about their added epidemiological value remains limited. Using aggregated, privacy-preserving mHealth data from six Chinese cities (July 2021–May 2022), we modelled transmission dynamics of emerging respiratory infections to quantify the heterogeneous effects of mHealth-triggered movement restrictions and risk-based quarantines across viral variants. We found that the mHealth-assisted interventions, together with population-wide lockdowns, could rapidly reduce the effective infection rate and drive daily incidence toward zero within two weeks, which was rarely achieved through traditional contact tracing alone. Scenario simulations further showed that in the absence of mHealth interventions, infections consistently propagated to connected cities across a wide range of epidemiological assumptions, contradicting the reality. These results suggest that early integration of geolocated mHealth tools with traditional epidemiological investigations enhances outbreak containment at both local and regional scales, providing quantitative, spatially explicit evidence to inform scalable mHealth integration strategies for future infectious threats with pandemic potential.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 8","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-08-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13458281/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148714291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spatial Heterogeneity in Heat-Related Mortality in the Valencian Region: Implications for Climate Adaptation Beyond Administrative Boundaries 巴伦西亚地区热相关死亡率的空间异质性:对行政边界以外气候适应的影响
IF 5 2区 医学
Geohealth Pub Date : 2026-08-07 DOI: 10.1029/2025GH001699
Laura Paredes-Fortuny, Coral Salvador, Ana M. Vicedo-Cabrera, Carmen Iñiguez, Samira Khodayar
{"title":"Spatial Heterogeneity in Heat-Related Mortality in the Valencian Region: Implications for Climate Adaptation Beyond Administrative Boundaries","authors":"Laura Paredes-Fortuny,&nbsp;Coral Salvador,&nbsp;Ana M. Vicedo-Cabrera,&nbsp;Carmen Iñiguez,&nbsp;Samira Khodayar","doi":"10.1029/2025GH001699","DOIUrl":"10.1029/2025GH001699","url":null,"abstract":"<p>The intensification of extreme heat events in the Mediterranean basin poses growing threats to public health, particularly in climate-vulnerable regions like the Valencian Region (eastern Spain). Despite the implementation of provincial and municipal heat prevention plans, their efficacy remains unevaluated, and most studies have focused on provincial capitals, potentially overlooking subregional variability. This study addresses these gaps by quantifying moderate and extreme heat-attributable mortality across 28 thermoclimatic areas (TAs)—a climatic subdivision of the Valencian Region— from 1975 to 2019, using a two-stage time-series analysis of high-resolution temperature and mortality data. Results reveal a distinct coastal–inland gradient, with significantly higher mortality impacts in inland TAs compared to coastal provincial capitals. Areas most impacted by extreme heat are concentrated in interior regions, while coastal capitals exhibit lower risks. These findings underscore the limitations of relying on administrative boundaries for public health surveillance and adaptation planning. The study highlights the value of climatically coherent zones, such as TAs, for improving the spatial resolution of early warning systems and tailoring heat prevention strategies. This scalable methodological framework provides critical insights for enhancing the design of heat adaptation plans not only in Spain but also in other Mediterranean and climate-sensitive regions.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 8","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-08-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13449177/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148690099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Increasing Urban Tree Canopy Associated With Reduced Mortality: A Longitudinal Analysis of Chicago Neighborhoods 增加城市树冠与降低死亡率相关:芝加哥社区的纵向分析。
IF 5 2区 医学
Geohealth Pub Date : 2026-08-05 DOI: 10.1029/2025GH001651
Harrison C. Garcia, Peter M. Graffy, Benjamin W. Barrett, Maxime A. Visa, Jenny Jia, Evan Mallen, Raed Mansour, Graham Briggs, Trent Ford, Donald J. Wuebbles, Norrina Allen, Teresa H. Horton, Abel Kho, Daniel E. Horton
{"title":"Increasing Urban Tree Canopy Associated With Reduced Mortality: A Longitudinal Analysis of Chicago Neighborhoods","authors":"Harrison C. Garcia,&nbsp;Peter M. Graffy,&nbsp;Benjamin W. Barrett,&nbsp;Maxime A. Visa,&nbsp;Jenny Jia,&nbsp;Evan Mallen,&nbsp;Raed Mansour,&nbsp;Graham Briggs,&nbsp;Trent Ford,&nbsp;Donald J. Wuebbles,&nbsp;Norrina Allen,&nbsp;Teresa H. Horton,&nbsp;Abel Kho,&nbsp;Daniel E. Horton","doi":"10.1029/2025GH001651","DOIUrl":"10.1029/2025GH001651","url":null,"abstract":"<p>Urban tree canopy is known to mitigate ambient heat and improve physical and mental health but the longitudinal interactions and impacts of tree canopy, temperature, and mortality are not well understood. Using high resolution tree canopy estimates, temperature, mortality, and demographic data from 2011 to 2021, we implemented negative binomial generalized estimating equations to model all-cause and disease-specific mortality based on tree canopy cover, year-to-year changes in tree canopy cover, and maximum temperature, adjusting for area-level demographics in Chicago, IL. We used K-means clustering to identify patterns of canopy, temperature, and mortality disparities across Chicago community areas. There were 220,711 decedents during the study period (115,974 male, 104,734 female; mean age at death: 69.4 ± 19.9 years). Existing canopy coverage was not statistically significantly associated with mortality (incidence rate ratio [IRR] = 0.995, 95% confidence interval [CI] = 0.984–1.007). However, each year-to-year percent increase in canopy was associated with around a 10% reduction in mortality (IRR = 0.902, [0.871–0.935]) with significant associations for cause-specific cardiovascular (IRR = 0.908, [0.869–0.948]), mental health (IRR = 0.836, [0.784–0.892]), musculoskeletal (IRR = 0.907, [0.832–0.989]), and respiratory (IRR = 0.887, [0.833–0.945]) diseases. Cluster analysis identified that neighborhoods on Chicago's South and West sides were characterized by high temperatures, greater absolute canopy loss despite elevated baseline canopy levels, and increased mortality. Among the hottest neighborhoods, canopy-temperature interaction models demonstrated that areas experiencing larger year-to-year canopy losses had higher yearly mortality. Protecting tree canopy cover from losses over time, particularly in vulnerable areas with higher temperatures, may present a key opportunity to reduce mortality and mitigate impacts of climate change.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 8","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-08-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13440163/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148680489","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Association Between Heavy Metal Exposure and Autism Spectrum Disorders: Discrepancies, Research Gaps, and Future Priorities of Human Epidemiological Studies 重金属暴露与自闭症谱系障碍之间的关系:差异、研究空白和人类流行病学研究的未来重点
IF 5 2区 医学
Geohealth Pub Date : 2026-07-31 DOI: 10.1029/2026GH001955
Aporajita Das Trisha, Md. Ashik Imran, Jaasia Momtahena Hafsa, Nayan Chandra Mohanto
{"title":"Association Between Heavy Metal Exposure and Autism Spectrum Disorders: Discrepancies, Research Gaps, and Future Priorities of Human Epidemiological Studies","authors":"Aporajita Das Trisha,&nbsp;Md. Ashik Imran,&nbsp;Jaasia Momtahena Hafsa,&nbsp;Nayan Chandra Mohanto","doi":"10.1029/2026GH001955","DOIUrl":"https://doi.org/10.1029/2026GH001955","url":null,"abstract":"<p>Autism spectrum disorder (ASD) in children is a major public health challenge. The potential epidemiological links between heavy metal exposure and ASD remains a controversial issue. This critical review examines the epidemiological discrepancies, including variations in exposure assessment, study design, and population differences that contribute to the ongoing debate. Key research gaps, such as the need for longitudinal studies and mechanistic insights, are addressed. Finally, we outline future priorities to advance understanding of heavy metals' role in ASD. Lead (Pb), cadmium (Cd), mercury (Hg), and arsenic (As) were selected heavy metals. The PubMed and Scopus databases, as well as the Google Scholar search engine, were searched to retrieve original research articles on human epidemiological studies that utilized the selected “exposure keywords” in conjunction with the “outcome keywords.” Finally, 36 full-length articles, irrespective of age, sex, regions, and race/ethnicity, were included for the present review. We revealed inconsistent associations between prenatal and childhood urinary, blood, and hair, As and Cd exposure, and ASD outcomes. In contrast, elevated prenatal and early childhood Pb and Hg concentrations in blood and hair samples showed a significant consistent association with both increased ASD risk and symptom severity, even after adjustment for key demographic and environmental confounders. The findings are inconsistent across metals and studies, and should be interpreted with caution due to potential residual confounding and heterogeneity in exposure assessment methods. Large prospective cohort studies are needed to clarify causal relationships. The path analysis of relevant biomarkers is also warranted to establish biological mechanism.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 8","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2026GH001955","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148617093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Heat and Dust Impacts on the Health of Refugees in Zaatari Refugee Camp 高温和沙尘对扎塔里难民营难民健康的影响
IF 5 2区 医学
Geohealth Pub Date : 2026-07-28 DOI: 10.1029/2025GH001687
Samer Makahleh, Maha Al-Harahsheh, Ka Wai Sit, Natasha Hessami, Wael K. Al-Delaimy
{"title":"Heat and Dust Impacts on the Health of Refugees in Zaatari Refugee Camp","authors":"Samer Makahleh,&nbsp;Maha Al-Harahsheh,&nbsp;Ka Wai Sit,&nbsp;Natasha Hessami,&nbsp;Wael K. Al-Delaimy","doi":"10.1029/2025GH001687","DOIUrl":"https://doi.org/10.1029/2025GH001687","url":null,"abstract":"<p>Climate-linked heatwaves and dust storms can exacerbate non-communicable disease (NCD) morbidity, yet quantitative evidence from displacement settings remains limited. We assessed short-term impacts of heat and dust events on symptom burden among Syrian refugees with non-communicable diseases (NCDs) in Jordan's Zaatari Camp. We conducted a prospective study of 660 adults receiving care at King Salman Humanitarian Aid and Relief Clinics (KS-Relief) clinics in Zaatari across three periods aligned to seasonal heatwaves. Self-reported symptoms following heatwaves and dust storms were collected via structured interviews. Repeated measures were analyzed using generalized linear mixed-effects models and generalized estimating equations with prespecified covariates. Heatwaves and dust storms were associated with increased symptom burden among participants with NCDs. Symptom burden was highest in Phase 1, the hottest period of 2024 in the Mafraq region (mean daily max 37.8°C; peak 43°C; multiple heatwave events and dust storm days), with more dyspnea, fatigue, and hypertension symptoms, especially among those with asthma or hypertension. Phase 2 (moderate heat with intermittent dust; mean daily max 34.1°C; peak 37°C) had lower odds of heatwave- and dust storm–related impacts than Phase 1 (odds ratio 0.54 and 0.62, respectively) with similar symptom profiles. Phase 3 (moderate heat; fewer dust storms; mean daily max 32.6°C) showed no significant change compared to Phase 2. Across phases, women, larger households, and asthma were associated with higher odds of adverse health impacts. In a displaced, low-resource setting, heatwaves and dust storms impose measurable, recurrent symptom burdens on adults living with NCDs, with heightened vulnerability among those with asthma and in larger households, and generally higher reported impacts among women. Camp-appropriate adaptation (improved cooling, shading, dust- mitigation) and targeted patient education and surveillance may reduce climate- sensitive NCD morbidity.</p>","PeriodicalId":48618,"journal":{"name":"Geohealth","volume":"10 7","pages":""},"PeriodicalIF":5.0,"publicationDate":"2026-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1029/2025GH001687","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148616542","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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