Laryngoscope Investigative Otolaryngology最新文献

{"title":"Nutritional Status and Outcomes Following Open Laryngeal Surgery for Laryngeal Cancer: A NSQIP Database Study","authors":"Emma R. Thompson,&nbsp;Nour Abdel-Azim,&nbsp;Kenneth Yan","doi":"10.1002/lio2.70257","DOIUrl":"10.1002/lio2.70257","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Malnutrition and weight loss in patients with laryngeal cancer impair immune function and wound healing. Understanding how underweight status impacts outcomes is crucial to improving care. Accordingly, we evaluated perioperative outcomes of patients undergoing laryngectomy for laryngeal cancer, with a secondary focus on patients with recent unintentional weight loss.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective cohort study used the American College of Surgeons National Surgical Quality Improvement Program database. CPT codes were used to identify patients undergoing open total or partial laryngectomies for cancer. Only those with underweight (&lt; 18.5) or normal weight (18.5–29.9) BMIs were included. A subgroup analysis assessed patients with recent unintentional weight loss. Univariate and multivariate analyses were performed, with significance set at <i>p</i> &lt; 0.05.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>2012 patients were analyzed: 276 underweight (79 female, 197 male) and 1736 normal weight (306 female, 1430 male). Age distribution among underweight patients was 2.5% (ages 20–44), 76.1% (ages 45–69), and 21.4% (ages 70–90), compared to 2.9%, 66.7%, and 30.1%, respectively, in normal-weight patients. Underweight patients were more likely to experience medical complications (<i>p</i> &lt; 0.001), longer hospital stays (<i>p</i> &lt; 0.001), wound disruptions (<i>p</i> = 0.002), and to have greater transfusion requirements (<i>p</i> &lt; 0.001). In those with recent, unintentional weight loss, underweight individuals were at increased risk of experiencing medical complications (<i>p</i> = 0.046) and requiring a transfusion (<i>p</i> &lt; 0.001), but were not more likely to experience wound disruptions (<i>p</i> = 0.119) or experience increased lengths of stay (<i>p</i> = 0.225).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Underweight status and recent weight loss are associated with heightened risks of perioperative medical complications and transfusions. Preoperative optimization may enhance surgical recovery and outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level 3.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12442250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145087931","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Pediatric Outcomes for Severe and Very Severe Obstructive Sleep Apnea After Total vs. Intracapsular Tonsillectomy","authors":"Jordyn A. Hurly,&nbsp;Anna Christina Clements,&nbsp;Marisa A. Ryan,&nbsp;Megan Ballard,&nbsp;Carolyn Jenks,&nbsp;David E. Tunkel,&nbsp;Jonathan M. Walsh","doi":"10.1002/lio2.70255","DOIUrl":"https://doi.org/10.1002/lio2.70255","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Intracapsular tonsillectomy is associated with decreased postoperative pain, shortened recovery, and decreased bleeding risk. No study has specifically investigated its use in patients with exclusively severe or very severe obstructive sleep apnea syndrome (OSAS). Our study aimed to report severe OSAS outcomes following intracapsular (IT) compared to total tonsillectomy (TT) in pediatric patients with severe and very severe OSAS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We conducted a retrospective study including patients ≤ 18 years of age who underwent adenotonsillectomy or tonsillectomy between June 2018 and June 2022 at a tertiary care center. Patients were categorized preoperatively as having severe OSAS (OAHI ≥ 10) or very severe OSAS (OAHI ≥ 30). Primary outcomes included obstructive apnea-hypopnea index (OAHI), oxygen saturation nadir, presence of hypercarbia, and respiratory disturbance index (RDI) as measured on postoperative polysomnography, as well as residual OSAS requiring CPAP.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Of 57 patients in this study, the mean age was 4.5 (±2.9) and 59.7% were male. There was no significant difference in postoperative residual OSAS outcomes following surgery for patients in either severity group, with a mean time to follow up polysomnogram of 237 (range: 24–885) days.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Our study reveals that for both severe OSAS and very severe OSAS, there is no difference in the primary outcome of postoperative OAHI with regard to surgical technique; however, long-term postoperative outcomes are still needed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>4.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70255","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145051160","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Modified 5-Item Frailty Index and Postoperative Outcomes Following Parotidectomy for Malignancy","authors":"Ariana L. Shaari,&nbsp;Keshav Kumar,&nbsp;Anthony M. Saad,&nbsp;Aman M. Patel,&nbsp;Paul Cowan,&nbsp;Andrey Filimonov,&nbsp;Ghayoour S. Mir","doi":"10.1002/lio2.70220","DOIUrl":"https://doi.org/10.1002/lio2.70220","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Frailty is a predictor of poor outcomes following surgery for malignancy. Our study investigates the association between the modified 5-item frailty index (mFI-5) and postoperative outcomes following parotidectomy for malignancy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Study Design</h3>\u0000 \u0000 <p>Cross-sectional database study.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Setting</h3>\u0000 \u0000 <p>National Surgical Quality Improvement Program (NSQIP).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The 2005–2018 NSQIP was retrospectively queried for patients undergoing parotidectomy for malignancy. Cases were stratified by the modified 5-item frailty index (mFI-5), which was calculated by the presence of 5 comorbidities: hypertension requiring medication, diabetes mellitus, congestive heart failure in the last 30 days, lung pathology, and functional health status. Univariate and multivariate analyses were performed to identify associations between mFI-5 and demographic, comorbid, and complication variables.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>A total of 14,567 patients were identified and stratified by the mFI-5. Univariate analysis showed an increasing incidence of American Society of Anesthesiologists (ASA) class, all comorbidities, and all complications with increasing mFI-5 score (<i>p</i> &lt; 0.001). Multivariable regressions showed increased odds of any surgical complication in patients with mFI-5 ≥ 2 compared with mFI-5 = 0 (aOR 2.56; 95% CI: 1.37–4.76, <i>p</i> = 0.011), as well as increased odds of unplanned readmission (aOR 4.02; 95% CI: 1.16–13.97, <i>p</i> = 0.032) and reoperation (aOR 6.61; 95% CI: 1.07–40.68, <i>p</i> = 0.042).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The mFI-5 is associated with increased incidence of comorbidities and complications, as well as increased odds of surgical complications, unplanned readmission, and reoperation in patients undergoing parotidectomy for malignancy, independent of age and ASA class. The mFI-5 can be utilized in the risk stratification of these patients.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70220","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145051161","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"“Who Needs More Help?”: The Predictors of Continued Smoking in Laryngeal Cancer Patients at Different Periods","authors":"Zeliha Kübra Çakan,&nbsp;Doğan Çakan,&nbsp;Sevda Yener,&nbsp;Haluk Çevik,&nbsp;Fatma Şevval Güçlü,&nbsp;Harun Cansız,&nbsp;Haydar Murat Yener","doi":"10.1002/lio2.70207","DOIUrl":"https://doi.org/10.1002/lio2.70207","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to identify factors associated with continued smoking before and after treatment in laryngeal cancer (LC) patients.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This retrospective study included 108 patients, evenly distributed into three groups based on primary treatment: radiotherapy (RT)/chemoradiotherapy, transoral laser surgery (TOLS), and open-partial laryngectomy (OPL). Patients who remained abstinent from smoking for at least 6 months at the 1st year were accepted as ex-smokers. The relationship between patients' smoking status and demographic characteristics, disease- and treatment-related parameters, and data obtained via self-questionnaires at pre-treatment, the 1st month, and 1st year post-treatment follow-ups was analyzed statistically.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Patient age, education level, smoking intensity, perceived disease seriousness, importance of smoking cessation, information satisfaction, pre-treatment quality of life (QoL), and treatment method differ between LC patients who quit and those who continue smoking. Potential negative predictors for pre-treatment cessation and ex-smoker status include advanced age and age &gt; 64.5 years, lower education level, advanced and &gt; 47 pack-years smoking consumption, low perceived disease seriousness, low importance on cessation, poor pre-treatment QoL, and less invasive treatment. Notably, cessation before treatment might be the strongest predictor of being an ex-smoker, with an OR of 47.6 (<i>p</i> &lt; 0.05).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study identified the potential predictors of smoking cessation in the post-diagnosis period, and might facilitate the detection of high-risk patients who need intensive smoking cessation interventions.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level 3.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70207","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145051159","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Approach to the Dynamics of the Vocal Cords During the Exploration With Flexible Laryngeal Stroboscopy","authors":"Walter Tenesaca,&nbsp;Roberto Fernández-Baillo,&nbsp;Isabel Cardoso,&nbsp;Vicente Pino,&nbsp;Emerson Chachi","doi":"10.1002/lio2.70219","DOIUrl":"https://doi.org/10.1002/lio2.70219","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The mucosal wave (MW) is fundamental to assessing vocal fold function, with laryngeal stroboscopy (LS) serving as a pivotal tool in its evaluation. However, technical factors associated with LS may alter the basal oscillatory dynamics of the free edges (FEs), which may bias the interpretation of results. This study aimed to analyze the dynamics of FEs, particularly MW, from the correlates extracted using a voice signal analysis method during LS, comparing it with habitual phonation without LS. Additionally, it was determined if this method can complement LS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>This descriptive study analyzed voice recordings from a sample of 137 adult subjects categorized into three groups with different conditions in their vocal folds. Voice recordings were processed using the Voice OnlineLab VCS tool. All participants had their speech signal recorded at natural pitch and volume in two situations: phonation without LS and phonation during LS. We studied the parameters: F0, tension index, glottal gap size, and MW index, closed/open phases. Statistical analysis was conducted based on the distribution values and mean differences according to the phonation situation, group, and gender. Pearson's correlation coefficient was employed to establish relationships between parameters, and Student's <i>t</i>-test was used to identify differences and test hypotheses.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>During LS, mean F0 values increased significantly. In addition, variations were observed in the correlates that reflected the degree of tension, contact type, and the resulting MW. Furthermore, distinct compensatory patterns were identified between male and female participants.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>The findings indicate important changes in patients' phonatory gestures during LS. These alterations may bias clinicians' assessments of FEs oscillatory dynamics. Therefore, practitioners using LS in clinical practice should consider these findings.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Level 2.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70219","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012926","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Blood Labyrinth Barrier Waste Clearance as Assessed by GBCAs on MRI: A Scoping Review","authors":"Syed Ameen Ahmad,&nbsp;Emily Y. Huang,&nbsp;Joon Soo Kim,&nbsp;Yassine Balhi,&nbsp;Marcus Spann,&nbsp;Bryan K. Ward","doi":"10.1002/lio2.70240","DOIUrl":"https://doi.org/10.1002/lio2.70240","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The discovery of the glymphatic system in the brain and eye has raised the hypothesis of a similar system in the inner ear. Dysfunctional lymph fluid dynamics may contribute to inner ear conditions such as Meniere's Disease (MD) and endolymphatic hydrops (EH). This scoping review evaluates inner ear waste clearance mechanisms by tracking gadolinium-based contrast agent (GBCA) signal over time using magnetic resonance imaging.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Data Sources</h3>\u0000 \u0000 <p>PubMed, Embase, Cochrane, Web of Science, and Scopus.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Review Methods</h3>\u0000 \u0000 <p>A systematic search identified studies reporting inner ear GBCA signal &gt; 4 h after intravenous (IV) administration. Data on study design, cohort characteristics, and time points were extracted.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifteen studies (three animal; 12 human) met inclusion criteria. Three studies had a goal of studying clearance. Animal studies demonstrated a decrease in GBCA signal following a 4-h peak. Of the human studies, three analyzed healthy controls, four studied EH without MD, three focused on MD, and two focused on neurological disorders but provided insight into inner ear enhancement. In healthy and MD ears, the internal auditory canal was enhanced before other inner ear structures. In EH, a reduced superior petrosal sinus area was noted, and delayed excretion rates were observed in MD patients 24 h post-IV administration. A positive association between endolymph and perilymph signal was identified in EH patients after 24 h.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Most studies were not designed to assess clearance mechanisms. Future in vivo and histopathological studies are needed to clarify the potential presence of glymphatic system involvement in the inner ear.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70240","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012927","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Topical Anesthesia and Olfactory Capability: A Pilot Study","authors":"Maxime Fieux,&nbsp;Esther Wang,&nbsp;David T. Liu,&nbsp;Zara M. Patel","doi":"10.1002/lio2.70250","DOIUrl":"https://doi.org/10.1002/lio2.70250","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Topical anesthesia (TA) of the nasal fossa has been shown to be sufficient for patient comfort during nasal endoscopy. However, investigators need to know how soon after the administration of TA they can accurately evaluate olfactory capability. Thus, the main aim of this study was to assess, in healthy volunteers (HV), when the effects of TA wear off to accurately measure olfactory capability after its administration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>A prospective, single-center, pilot study was conducted to evaluate the duration of the effect of TA on olfactory capability, using the UPSIT. Thirty healthy volunteers were recruited and analyzed. Following baseline testing (UPSIT), TA was administered intranasally (lidocaine + oxymetazoline). Then, participants underwent three additional UPSIT evaluations at distinct time points: immediately post-application (T0), 10 min (T + 10), and 30 min post-application (T + 30). The primary outcome was the change in UPSIT score from baseline to each subsequent time point. Paired <i>t</i>-tests were applied to compare within-subject score differences across time points. Significance was defined as <i>p</i> &lt; 0.05, and the R software was used.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>For the 30 HV included, the mean UPSIT at T0 was 32.8 ± 3.1. At T1, the mean UPSIT (29.6 ± 4.0) was significantly lower than at T0 (3.13 ± 3.7-point, <i>p</i> &lt; 0.0001). At T2, the mean UPSIT was 31.7 ± 4.2, without any significant difference from T0 (−1.03 ± 3.5-point, <i>p</i> = 0.350). At T3, the mean UPSIT was 31.7 ± 3.1, without any significant difference compared to T0 (−1.07 ± 2.6-point, <i>p</i> = 0.067). Regarding subgroup analysis between healthy volunteers with or without ITH, their own perception of smell and UPSIT were significantly different.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Immediately after receiving 4 sprays per nostril, the mean UPSIT—with testing begun directly after the spray was administered—was significantly lower than baseline, dropping under the threshold for normal olfactory function. It was fully recovered by ten min.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>3.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70250","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145012925","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Feasibility Study of Virtual Reality and 360° Video Training for Anterior Nasal Packing","authors":"Holly Mould,&nbsp;Andrew Kinshuck,&nbsp;Jonathan R. Abbas,&nbsp;Nick Culley,&nbsp;Elena Karakashevska","doi":"10.1002/lio2.70243","DOIUrl":"https://doi.org/10.1002/lio2.70243","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objectives</h3>\u0000 \u0000 <p>Virtual reality (VR) simulators have been well established in ear, nose, and throat (ENT) training for many years. However, most are aimed at specialist trainee level or above, with no current VR ENT training packages for foundation year doctors, who perform a significant amount of out-of-hours ENT care. Novel VR and 360° video packages for the training of anterior nasal packing were developed and evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>In this feasibility study, 16 foundation year doctors were pseudorandomised to a three-arm study: using solely the VR simulation, solely the 360° video, or the video followed by the VR simulation. Pre- and post-intervention questionnaires were devised using expert consensus, and confidence, competence, objective knowledge, usability, face and content validity, and qualitative data were all evaluated.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>There was a significant increase between pre- and post-intervention confidence, competence, and knowledge for the whole cohort. The 360° video used alongside the VR simulation and alone was deemed user-friendly. All packages achieved content validity, whilst the VR simulation did not achieve face validity, with responses indicating that the haptic feedback requires improvement. Participants found the packages engaging and immersive, encouraging safe practice in an enjoyable manner.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>These novel VR and 360° videos are engaging ways of effectively increasing confidence, competence, and knowledge in anterior nasal packing. Further adjustments should be made to the haptic feedback of the VR simulator to make it more realistic.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>N/A.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 5","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-09-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70243","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145013015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear Implantation for Sensorineural Hearing Loss Related to Cochlear Aqueduct Obstruction by a Jugular Foramen Tumor","authors":"Nicole Ewer,&nbsp;Mana Espahbodi,&nbsp;Kathryn Johnson,&nbsp;Richard H. Wiggins III,&nbsp;Richard K. Gurgel,&nbsp;Neil S. Patel","doi":"10.1002/lio2.70171","DOIUrl":"https://doi.org/10.1002/lio2.70171","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Introduction</h3>\u0000 \u0000 <p>Cochlear implantation (CI) may be used as a viable method for restoring hearing in patients with sensorineural hearing loss (SNHL) caused by jugular foramen tumors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Materials and Methods</h3>\u0000 \u0000 <p>42-year-old female presenting with sudden-onset SNHL, pulsatile tinnitus, and otalgia, with a PTA of 119 dB and AzBio sentence score of 0% in quiet. Brain MRI identified a 22 mm tumor within the left jugular foramen and hypoglossal canal involving the cochlear aqueduct. Patient underwent stereotactic radiosurgery (SRS), with the tumor receiving 15 Gy in a single fraction, followed by a left CI with full electrode insertion without resistance. Main outcome measures included audiometric outcomes pre- and post-CI, including PTA and AzBio sentence scores in quiet, and MRI imaging of the tumor pre- and post-SRS.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Upon activation of CI, PTA had improved to 42 dB with AzBio sentence score of 50% in quiet within 1 month after activation. One-year follow-up revealed PTA of 38 dB and AzBio sentence score of 29% in quiet. Datalogging at 1 month after CI activation revealed 11.4 h per day of CI use at 1 month and 5.5 h per day at 1 year after CI activation. Patient reported that aural rehabilitation exercises were stopped during this time period. Post-SRS imaging revealed minimal growth of the jugular foramen tumor.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This report demonstrates that CI for asymmetric sensorineural hearing loss or single-sided deafness related to cochlear aqueduct obstruction from jugular foramen pathology yields outcomes similar to conventional CI recipients. Imaging surveillance of the tumor remains feasible for tumors treated with SRS. This case report provides valuable insight and offers guidance for surgeons and patients facing a similar clinical scenario.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>4.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70171","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905381","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Clinical Validation of Manual Measurement of Cochlea Length With Post-Operative Electrode Insertion Depth: A Pilot Study","authors":"Fei Wang,&nbsp;Dharmikkumar Anaghan,&nbsp;Anandhan Dhanasingh,&nbsp;Lian Hui","doi":"10.1002/lio2.70237","DOIUrl":"https://doi.org/10.1002/lio2.70237","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To clinically validate manual measurement of cochlear length from pre-operative image of cochlea with post-operative image of cochlear implant (CI) electrode.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Temporal bone computer tomography (CT) scans of 23 ears were available for this pilot study. The inner ear was three-dimensionally (3D) segmented, and cochlea length was manually measured for preferred angular depth depending on inner ear anatomical types for CI electrode length selection. Post-operative CT scans were made available for electrode reconstruction to measure electrode length inside the cochlea to validate pre-operative measurement of cochlear length.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Normal anatomy (NA) inner ear was identified in 11 ears, enlarged vestibular aqueduct syndrome (EVAS) in 4 ears, incomplete partition (IP) type I in 2 ears, cochlear hypoplasia (CH) in 5 ears, and otosclerosis in 1 ear. Cochlear length was measured for 650° of angular depth in NA ears, 540° in EVAS and otosclerosis, 360° in IP type I, and for available angular depth depending on the development of the cochlea in CH type. Based on the cochlea length measured, a closely matching electrode length was chosen for implantation from 1 CI manufacturer. Partial insertion was seen in 2 NA ears, 1 otosclerosis ear, and 1 CH ear, whereas full insertion of the chosen electrode was achieved in the remaining 19 ears.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Manual measurement of cochlea length from 3D image of cochlea is a practical way of choosing electrode length for preferred angular insertion depth depending on the cochlea anatomy.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Level of Evidence</h3>\u0000 \u0000 <p>Between level 2 and 3.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48529,"journal":{"name":"Laryngoscope Investigative Otolaryngology","volume":"10 4","pages":""},"PeriodicalIF":1.7,"publicationDate":"2025-08-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/lio2.70237","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144905384","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}