Association of Life's Essential 8 With Hearing Loss and Tinnitus in U.S. Adults

IF 1.7 4区 医学 Q2 OTORHINOLARYNGOLOGY
Xing Lin, Yuxi Lin, Siyi Tang, Huimin Cai, Heng Xiao, Chang Lin, Shengnan Ye
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引用次数: 0

Abstract

Objective

To investigate the association between cardiovascular health, measured by Life's Essential 8 (LE8) score, and hearing loss and tinnitus among U.S. adults.

Methods

A cross-sectional analysis was conducted on 4624 adults (≥ 20 years) from NHANES 2005–2018 cycles. Cardiovascular health was assessed via the LE8 score, encompassing eight health behaviors and factors. Audiometry-measured speech-frequency hearing loss, defined as pure-tone average (PTA) ≥ 20 dB in the better ear at 500–4000 Hz, and subjective hearing loss and tinnitus were assessed using self-reported questionnaires. Multivariable logistic regression models adjusted for confounders examined associations between LE8 scores and auditory conditions. Additional analyses included restricted cubic spline regression, subgroup, and sensitivity analyses.

Results

Higher LE8 scores, indicating better cardiovascular health, were significantly associated with lower odds of audiometry-measured speech-frequency hearing loss (adjusted OR: 0.84; 95% CI: 0.77–0.92), subjective hearing loss (adjusted OR: 0.82; 95% CI: 0.77–0.88), and tinnitus (adjusted OR: 0.88; 95% CI: 0.81–0.96). Subgroup analyses showed consistent associations for audiometry-measured hearing loss and tinnitus across demographic strata, while findings for subjective hearing loss varied by sex. Sensitivity analyses confirmed the robustness of the findings.

Conclusions

Better cardiovascular health, as measured by LE8 score, is associated with lower odds of hearing loss and tinnitus among U.S. adults. These findings suggest that the LE8 score may serve as a valuable integrated metric for evaluating cardiovascular health in relation to auditory outcomes.

Level of Evidence

2b.

Abstract Image

美国成年人听力损失和耳鸣与生命必要因素的关联
目的探讨美国成年人心血管健康状况(LE8)与听力损失和耳鸣之间的关系。方法对来自NHANES 2005-2018周期的4624名成年人(≥20岁)进行横断面分析。通过LE8评分评估心血管健康,包括8种健康行为和因素。听力测量测量的语音频率听力损失,定义为500-4000 Hz时较好耳的纯音平均(PTA)≥20 dB,以及主观听力损失和耳鸣,采用自我报告的问卷进行评估。校正混杂因素的多变量逻辑回归模型检验了LE8分数与听觉状况之间的关联。其他分析包括限制三次样条回归、亚组和敏感性分析。LE8评分越高,表明心血管健康状况越好,与听力测量测得的言语频率听力损失(校正OR: 0.84; 95% CI: 0.77-0.92)、主观听力损失(校正OR: 0.82; 95% CI: 0.77-0.88)和耳鸣(校正OR: 0.88; 95% CI: 0.81-0.96)的几率较低显著相关。亚组分析显示,听力学测量的听力损失与耳鸣之间存在一致的关联,而主观听力损失的结果因性别而异。敏感性分析证实了研究结果的稳健性。结论:在美国成年人中,以LE8评分衡量的心血管健康状况较好与听力损失和耳鸣的几率较低有关。这些发现表明,LE8评分可以作为评估心血管健康与听觉结果相关的有价值的综合指标。证据级别2b。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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来源期刊
CiteScore
3.00
自引率
0.00%
发文量
245
审稿时长
11 weeks
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