Emanuele Cassioli, Lorenzo Lucherini Angeletti, Eleonora Rossi, Giulia Selvi, Elena Riccardi, Serena Siviglia, Roberta Buonanno, Valdo Ricca, Giovanni Castellini
{"title":"Leptin Levels in Acute and Recovered Eating Disorders: An Arm-Based Network Meta-Analysis","authors":"Emanuele Cassioli, Lorenzo Lucherini Angeletti, Eleonora Rossi, Giulia Selvi, Elena Riccardi, Serena Siviglia, Roberta Buonanno, Valdo Ricca, Giovanni Castellini","doi":"10.1002/erv.3163","DOIUrl":"10.1002/erv.3163","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to provide a BMI-adjusted meta-analytical calculation of blood leptin levels across different eating disorders (EDs) including anorexia nervosa (AN), bulimia nervosa (BN), binge eating disorder (BED), recovered EDs, and healthy controls (HCs). The goal was to understand BMI-independent leptin alterations and their potential as biomarkers.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>PubMed and ClinicalTrials.gov were searched for studies reporting serum leptin in AN, BN, BED, or recovered EDs. A multilevel network meta-analysis using a linear mixed-effects meta-regression model, adjusting for BMI, sex, and assay type, was performed on 146 studies (5048 patients, 3525 controls).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Significant differences in leptin levels were found across EDs. AN patients exhibited the lowest leptin levels, while BED patients had the highest. BN and recovered AN patients had leptin levels similar to AN, significantly lower than HCs. BMI, sex, and assay type were significant covariates. The model accounted for heterogeneity due to diagnostic criteria, assay types, and study-level differences.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Leptin levels in EDs are significantly altered beyond BMI effects, suggesting disease-specific factors. These findings support leptin's potential as a biomarker for ED staging and prognosis. Further research is needed to explore leptin's role in ED pathogenesis and trajectory, to identify subpopulations and improve clinical interventions.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"525-537"},"PeriodicalIF":3.9,"publicationDate":"2024-12-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.3163","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142792532","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anouk Sauve, Catarina Silva, Doriane Costa, David Da Fonseca, Marion Givaudan, Isabelle Charvin, Flora Bat-Pitault
{"title":"Adolescent Girls With Anorexia Nervosa Clinical Profiles in Relation to Their Social Networks Use","authors":"Anouk Sauve, Catarina Silva, Doriane Costa, David Da Fonseca, Marion Givaudan, Isabelle Charvin, Flora Bat-Pitault","doi":"10.1002/erv.3157","DOIUrl":"10.1002/erv.3157","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>In recent years, social networks (SNs) have increasingly become a core activity adolescent's daily life. Their impact on mental health is an actual worldwide concern. This massive usage of social network has been suggested to increase the risk of depressive and anxiety disorders, as well as alterations in sleep quality and quantity. In particular, it has been suggested that it could increase concerns about body image and thereby encourage eating disorders. Aiming at further investigating these relations, this study examined, for the first time, the links between the clinical profile of adolescents with anorexia nervosa and SNs use patterns.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The sample included 131 adolescent girls with anorexia nervosa who completed an online survey assessing their SNs practices in terms of duration, intensity and function of SNs use, misuse and addictive tendencies, as well as the number of online peers. Clinical characteristics such as eating behaviours, body image perception, depression, anxiety and sleep quality were also assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>showed that adolescents with anorexia nervosa spend more than 3 h per day on SNs. Those spending 5 h per day or more preferred a passive use, with limited connection with peers and greater clinical difficulties. In addition, high problematic use of SNs significantly aggravated eating behaviour, dysmorphophobia, depressive symptoms and sleep impairment. The activities performed on SNs were not significantly associated with variations in clinical characteristics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Presents findings suggests that a profile of social networking marked by a problematic, prolonged and passive use, is associated with more severe symptomatology in adolescent girls with anorexia nervosa. These first data could inspire professionals to encourage a SNs use favouring care and recovery, thereby supporting adolescents with an eating disorder but also their relatives.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"503-510"},"PeriodicalIF":3.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.3157","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Marieke Meier, Katrin Jansen, Hannah Vertgewall, Laurence Claes
{"title":"The Lifetime Prevalence of Non-Suicidal Self-Injury in Children and Adolescents With Eating Disorders—A Systematic Review and Meta-Analysis","authors":"Marieke Meier, Katrin Jansen, Hannah Vertgewall, Laurence Claes","doi":"10.1002/erv.3158","DOIUrl":"10.1002/erv.3158","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Eating disorders (EDs) and non-suicidal self-injury (NSSI) are both phenomena with onset in adolescence. Their co-occurrence is associated with higher symptom severity and an elevated risk of suicide. In this meta-analysis, we examine the lifetime prevalence of NSSI in youth with EDs.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>We searched PsycInfo, PubMed and previously published systematic reviews for studies reporting on lifetime NSSI prevalence among children and adolescents (19 years or younger) with an ED (anorexia nervosa, bulimia nervosa, binge eating or other specified feeding and EDs) published until June 2024. A generalized linear mixed model meta-analysis was performed to estimate the pooled prevalence. Meta-regressions and multivariate meta-analyses were conducted to estimate separate prevalence rates based on ED diagnosis and care frame (e.g., inpatient vs. outpatient), respectively.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Fifteen studies comprising 3311 children and adolescents were included. Pooled lifetime NSSI prevalence across all ED diagnoses was 34.2% [CI: 27.5%–41.7%]. Heterogeneity was large (<i>I</i><sup>2</sup> = 93.8%). Lifetime NSSI prevalence rates were significantly higher for participants with bulimia nervosa (53.6%) and those with anorexia nervosa binge-eating/purging type (51.9%) than for participants with anorexia nervosa restrictive type (15.8%).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>The small number of studies and the large heterogeneity limit the conclusiveness of this meta-analysis. Results suggest an even higher prevalence of lifetime NSSI in adolescents with an ED than in adults with an ED. The results support previous findings indicating higher prevalence rates of NSSI for EDs associated with binge eating and purging behaviours than for restrictive EDs.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"511-524"},"PeriodicalIF":3.9,"publicationDate":"2024-11-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.3158","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142755809","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Meital Gil, Yael Latzer, Noa Tziperman, Dan Farbstein, Helene Sher, Noam Weinbach
{"title":"The Influence of Negative Affect and Food Stimuli on Cognitive Flexibility in Adolescents With Anorexia Nervosa","authors":"Meital Gil, Yael Latzer, Noa Tziperman, Dan Farbstein, Helene Sher, Noam Weinbach","doi":"10.1002/erv.3159","DOIUrl":"10.1002/erv.3159","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Inflexible thinking among individuals with anorexia nervosa (AN) was proposed to reflect difficulties in set-shifting. However, studies assessing set-shifting in AN often find mixed results, especially in adolescent samples. It has been proposed that affective states and exposure to disorder-salient stimuli may modulate executive functions in AN. The current study examined the influence of induced negative emotion on the ability to shift toward or away from a food categorisation task among adolescents with AN.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>The study included 47 adolescents with AN and 41 healthy adolescents who performed a modified task-switching paradigm.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>No indication of general set-shifting difficulties among adolescents with AN was found. Nevertheless, the results showed that when negative emotion was induced, adolescents with AN shifted from a non-food categorisation task to a food categorisation task with greater efficiency compared to a neutral emotion condition. Emotion and switch type did not influence set-shifting abilities among healthy adolescents.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The findings indicate automatic and more efficient switching towards preoccupation with food among adolescents with AN while experiencing negative emotion. The results emphasise the important role played by situational factors in modulating cognitive abilities in individuals with AN.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"480-489"},"PeriodicalIF":3.9,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.3159","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752041","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mina Velimirović, Morgan Robison, Sophie Abber, Alan Duffy, Renee D. Rienecke, Jamie Manwaring, Dan V. Blalock, Megan Riddle, Philip S. Mehler, Thomas E. Joiner
{"title":"Anxiety, Obsessive-Compulsive, and Depressive Symptom Presentation and Change Throughout Routine Eating Disorder Treatment","authors":"Mina Velimirović, Morgan Robison, Sophie Abber, Alan Duffy, Renee D. Rienecke, Jamie Manwaring, Dan V. Blalock, Megan Riddle, Philip S. Mehler, Thomas E. Joiner","doi":"10.1002/erv.3160","DOIUrl":"10.1002/erv.3160","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The present study examined whether patients with binge/purge and restricting anorexia nervosa (AN-BP and AN-R), bulimia nervosa (BN), binge eating disorder (BED), avoidant/restrictive food intake disorder (ARFID), and other specified feeding and eating disorder (OSFED) differ in generalised anxiety disorder (GAD), obsessive-compulsive disorder (OCD), and depression <i>symptom</i> patterns and overall comorbid symptom severity at admission. We also assessed between-group differences in the patterns of change and overall comorbid symptom severity change from admission to discharge from routine eating disorder (ED) treatment at higher levels of care (HLOC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The initial sample included 3730 adults routinely assessed for GAD, depression, and OCD at admission and discharge from treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results and Conclusions</h3>\u0000 \u0000 <p>ED diagnostic groups exhibited somewhat different symptom patterns (e.g., AN-R and ARFID were more prone to GAD and OCD than depression symptoms; BED exhibited the opposite pattern) and overall symptom severity at admission (i.e., AN-BP and OSFED had the highest overall comorbid symptom severity; BED had the lowest). Although the overall symptom improvement was significantly greater in ARFID and BED than in AN-BP, AN-R, and OSFED, ED patients collectively and within each diagnostic group improved significantly in GAD, OCD, and depression symptoms following routine ED treatment at HLOC.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"490-502"},"PeriodicalIF":3.9,"publicationDate":"2024-11-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142752040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Zoe McClure, Christopher J. Greenwood, Matthew Fuller-Tyszkiewicz, Mariel Messer, Jake Linardon
{"title":"Application of Machine Learning Techniques to the Prediction of Onset and Persistence of Binge Eating: A Prospective Study","authors":"Zoe McClure, Christopher J. Greenwood, Matthew Fuller-Tyszkiewicz, Mariel Messer, Jake Linardon","doi":"10.1002/erv.3154","DOIUrl":"10.1002/erv.3154","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Machine learning (ML) techniques have shown promise for enhancing prediction of clinical outcomes; however, its application to predicting binge eating has been scarcely explored. We applied ML techniques to predict binge eating onset (vs. continued absence) and persistence (vs. remission) over time.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Data were used from a larger prospective study of 1106 participants who were assessed on a range of putative risk, maintaining, and protective factors at baseline and 8 months follow-up. Nine ML models for classification were developed and compared against a generalised linear model (GLM) for predicting onset (<i>n</i> = 334) and persistence (<i>n</i> = 623) outcomes using 39 self-reported baseline variables as predictors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>All models performed poorly at predicting onset (AUC = 0.49–0.61) and persistence (AUC = 0.50–0.59) outcomes, with ML models demonstrating comparable performance to the GLM.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>We suspect that poor ML performance may have been a result of the limited set of self-reported baseline predictors used to generate prediction models. Improved predictive accuracy and optimisation of ML models in future research may require consideration of a larger, more disparate set of predictors that also incorporate various data types, such as neuroimaging, physiological, or smartphone sensor data.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"472-479"},"PeriodicalIF":3.9,"publicationDate":"2024-11-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
An Dang, Roser Granero, Isabel Sanchez, Laura Gálvez Solé, Jessica Jimenez-del Toro, Magda Rosinska, Susana Jimenez-Murcia, Isabel Krug, Fernando Fernandez-Aranda
{"title":"Unveiling Severity Indicators for Anorexia and Bulimia Nervosa Treatment Success: DSM–5 Versus ICD–11 Versus Drive for Thinness","authors":"An Dang, Roser Granero, Isabel Sanchez, Laura Gálvez Solé, Jessica Jimenez-del Toro, Magda Rosinska, Susana Jimenez-Murcia, Isabel Krug, Fernando Fernandez-Aranda","doi":"10.1002/erv.3156","DOIUrl":"10.1002/erv.3156","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This study aimed to compare treatment outcomes associated with three severity indicators—DSM–5 for anorexia nervosa (AN) and bulimia nervosa (BN), ICD–11 for AN, and drive for thinness (DT) for AN and BN—within a treatment-seeking population.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A total of 628 female participants diagnosed with either AN (<i>n</i> = 266; mean age = 26.71) or BN (<i>n</i> = 362; mean age = 29.49) were recruited from an ED unit. Upon admission, participants were classified based on DSM–5 (AN and BN) and ICD–11 severity categories. They underwent CBT-E comprehensive manualised programs, according to ED subtype, and were categorised into ‘full remission’, ‘partial remission’, ‘non-remission’ or ‘drop-out’ based on DSM–5 diagnostic criteria at discharge.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Significant associations were found only for ICD–11 AN severity groups (<i>p</i> = 0.03, Cramer's <i>V</i> = 0.18), with ‘dangerously low BMI’ associated with poorer outcomes than ‘significantly low BMI’. No other significant relationships were found with DSM–5 or DT severity groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>This study reveals the limitation of using a single severity indicator and emphasises the necessity of a comprehensive assessment to capture the complexities of AN and BN. Future research should also evaluate the validity of these severity measures across various factors, including biological correlates and psychopathology.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"460-471"},"PeriodicalIF":3.9,"publicationDate":"2024-11-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142693724","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mariana P. Lopes, Sana Ahmed, Lily Beaman, Brendon Stubbs, Iain C. Campbell, Ulrike Schmidt, Lauren Robinson
{"title":"Bone Fracture History in Women With First Episode or With Persistent Anorexia Nervosa","authors":"Mariana P. Lopes, Sana Ahmed, Lily Beaman, Brendon Stubbs, Iain C. Campbell, Ulrike Schmidt, Lauren Robinson","doi":"10.1002/erv.3153","DOIUrl":"10.1002/erv.3153","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To investigate fractures history in women with first episode anorexia nervosa (AN) (FE-AN: ≤ 3 years duration) and those with persistent AN (P-AN: ≥ 7 years), compared to healthy controls (HC).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>One hundred nineteen women (FE-AN = 49, P-AN = 46 and HC = 24) completed online questionnaires on eating disorders symptoms, their menstrual and their fracture history.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Average illness duration was 1.9 years (SD = 0.8) in FE-AN and 15.3 years (SD = 8.5) in P-AN. Lifetime history of all fractures, including stress fractures, was higher in AN groups (FE-AN = 33.3%; P-AN = 37.8%) than in HC (4.2%, <i>p</i> < 0.001). P-AN participants were 13.4 times more likely to report a fracture compared to HC, irrespective of age, whereas F-AN participants were 10.3 times more likely. In P-AN, higher BMI, shorter duration of amenorrhoea and history of pregnancy were inversely associated with fracture number.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>There is an increased risk of bone fracture even in the early stages of AN. This could be related to a time lapse between the initial symptoms of AN and formal diagnosis. This suggests guidelines recommending bone screening after 2-years of persistent low weight for adults should be revisited, and the risk of bone problems should be part of the dialogue between clinicians, patients and carers at the earliest opportunity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 3","pages":"447-459"},"PeriodicalIF":3.9,"publicationDate":"2024-11-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.3153","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Anna Riva, Eleonora Brasola, Sofia Elena Sforza, Mirella Marfone, Francesco Biso, Renata Nacinovich
{"title":"Anorexia Nervosa in Comorbidity With Borderline Personality Disorder in Adolescence: A Specific Clinical Endophenotype?","authors":"Anna Riva, Eleonora Brasola, Sofia Elena Sforza, Mirella Marfone, Francesco Biso, Renata Nacinovich","doi":"10.1002/erv.3155","DOIUrl":"10.1002/erv.3155","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Anorexia nervosa and borderline personality disorder are often associated and share some core elements, including emotional dysregulation and affective instability. Nevertheless, the association of these two conditions in adolescence is still little studied.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>The present study aims at investigating, through a multidimensional assessment, the psychopathological characteristics of adolescents affected by anorexia nervosa in comorbidity with borderline personality disorder on a sample of 127 female adolescents, through the comparison with adolescents with borderline personality disorders and adolescents with anorexia nervosa. All participants completed a validated psychometric battery assessing alexithymia (Toronto Alexithymia Scale-20), depression (Children's Depression Inventory), psychological symptoms (Symptom Checklist-90–Revised) and psychological symptoms relevant in eating disorders (Eating Disorders Inventory-3).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Adolescents with anorexia nervosa in comorbidity with borderline personality disorder show intermediate features between the two disorders individually in the general psychopathological profile, but a peculiar psychological profile regarding the eating symptomatology, with worse features compared to adolescents with the sole anorexia nervosa.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Results suggest a peculiar clinical and psychopatological endophenotype in adolescents with anorexia nervosa in comorbidity with borderline personality disorders, indicating the need to define specific and tailored treatment for this population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 2","pages":"434-443"},"PeriodicalIF":3.9,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The Thorny Issue of Atypical Anorexia Nervosa: Clinicians' Perspectives on How It Should Be Defined","authors":"Jessica Beard, Glenn Waller","doi":"10.1002/erv.3152","DOIUrl":"10.1002/erv.3152","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Atypical Anorexia Nervosa (AAN) is an ill-defined diagnosis. Little is known about how eating disorder clinicians perceive the utility of the diagnosis, and what changes they believe would add to that utility. This qualitative study aimed to explore clinicians' perspectives on refining the DSM-5 AAN diagnosis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Content analysis of text was used to categorise 47 responses to the questions: “What changes are required to the DSM-5 definition of AAN?”, and “How do you think significant weight loss should be defined?”.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Over 27% of clinicians advocated removing the AAN diagnosis or combining it with Anorexia Nervosa, while nearly 15% reported concerns about the requirement for ‘significant weight loss’. Over 87% of clinicians suggested ways (often inconsistent across clinicians) to define ‘significant weight loss’, with emphasis on the need for a specified rate (i.e., amount of loss/time) and consideration of physical health impacts.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Clinicians broadly agree that revisions are necessary to the current AAN definition. However, while some propose specific modifications (e.g., defining ‘significant weight loss’), others advocate for the complete removal of the diagnosis. The breadth of suggestions for how to define ‘significant weight loss’ highlights the ongoing lack of consensus on AAN's relevance as a diagnostic entity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"33 2","pages":"426-433"},"PeriodicalIF":3.9,"publicationDate":"2024-11-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11786928/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142669470","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}