European Eating Disorders Review最新文献

{"title":"Longitudinal Associations of Body Image Flexibility With Eating Disorder Psychopathology, Eating-Related Psychosocial Impairment, and Psychological Distress in Chinese Cisgender Men and Women","authors":"Peiyi Wang,&nbsp;Yueyang Xiao,&nbsp;Yunyi Cheng,&nbsp;Reza N. Sahlan,&nbsp;Wesley R. Barnhart,&nbsp;Jason M. Nagata,&nbsp;Jinbo He","doi":"10.1002/erv.70120","DOIUrl":"10.1002/erv.70120","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Body image flexibility is a clinically relevant protective process linked to lower eating disorder psychopathology and better psychological functioning, yet its longitudinal role in shaping psychological risk and resilience remains unclear, particularly across women and men in non-Western contexts. This study examined its bidirectional associations with thinness- and muscularity-oriented disordered eating, eating-related psychosocial impairment, and psychological distress among Chinese adults.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Chinese adults completed baseline (<i>N</i> = 800; 400 women and 400 men) and eight-month follow-up (<i>N</i> = 491; 246 women and 245 men) online surveys. Cross-lagged panel models were used to examine bidirectional associations.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Higher body image flexibility at T1 was related to lower levels of thinness-oriented disordered eating, muscularity-oriented disordered eating, eating-related psychosocial impairment, and psychological distress at T2. Conversely, higher levels of thinness-oriented disordered eating, muscularity-oriented disordered eating, eating-related psychosocial impairment, and psychological distress at T1 were related to lower body image flexibility at T2. These bidirectional associations were consistent across women and men.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Body image flexibility can function both as a protective resource and as a process susceptible to psychological strain. Intervention efforts should be gender inclusive and target multidimensional forms of eating disorder psychopathology alongside psychological well-being.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1294-1303"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147730389","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Avoidant/Restrictive Food Intake Disorder Dimensions and Obsessive-Compulsive Symptomatology","authors":"Mariana Valdez Aguilar,&nbsp;Gabriela K. Giulumian,&nbsp;Isabel Rodriguez,&nbsp;Jessica H. Baker,&nbsp;Preina P. Surti,&nbsp;Lisa Dinkler,&nbsp;Jerry Guintivano,&nbsp;Jessica S. Johnson,&nbsp;Casey M. MacDermod,&nbsp;Shelby N. Ortiz,&nbsp;Emily M. Pisetsky,&nbsp;Jennifer P. White,&nbsp;Nadia Micali,&nbsp;Cynthia M. Bulik,&nbsp;Laura M. Thornton,&nbsp;Ya-Ke Wu","doi":"10.1002/erv.70122","DOIUrl":"10.1002/erv.70122","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Although obsessive-compulsive disorder (OCD) commonly co-occurs with anorexia nervosa and bulimia nervosa, less is known about its relationship with avoidant/restrictive food intake disorder (ARFID) dimensions. Whether associations between ARFID dimensions and OCD differ by sex is also unclear. We examined associations between ARFID dimensions and OCD symptoms by sex, accounting for depression and anxiety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Data from 3120 participants ages 15+ in the ARFID Genes and Environment (ARFID-GEN) study were analyzed. ARFID dimensions (i.e., sensory sensitivity; low appetite/lack of interest in food; and fear of aversive consequences), OCD symptoms, anxiety, and depression were assessed using validated self-report measures. We evaluated associations between ARFID dimensions and OCD symptoms using general linear models, adjusting for depression and anxiety.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>ARFID dimensions were significantly associated with OCD symptoms. After adjusting for depression and anxiety, these associations were attenuated but remained significant for all ARFID dimensions. Associations between ARFID dimensions and OCD symptoms varied by sex.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>The relation between ARFID symptomatology and OCD warrants further exploration across the developmental spectrum in which ARFID appears. Clinically, bidirectional screening may improve diagnostic clarity and be informative to tailor interventions appropriately.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>ARFID-GEN is registered in clinicaltrials.gov (NCT05605067)</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1327-1335"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70122","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785697","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Weight Suppression, Brain Reward Response to Food Cues, and Bulimic Behaviours: A Pilot fMRI Study","authors":"Simar Singh,&nbsp;Kanchana Jagannathan,&nbsp;Anna Rose Childress,&nbsp;Michael R. Lowe","doi":"10.1002/erv.70127","DOIUrl":"10.1002/erv.70127","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Weight suppression (WS), or the difference between one's highest past and current weights, may help maintain bulimia nervosa (BN) by altering reward response to food cues. This pilot study tested associations among WS, brain reward activation to food cues, and BN behaviours.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Twenty women with BN were shown images of milkshake or tasteless control solution, followed by receipt of the corresponding beverage during fMRI. Regressions examined associations between brain activation in a priori regions of interest and WS and BN behaviours (i.e., objective binge-eating episodes, self-induced vomiting episodes, dietary restraint), corrected at <i>k</i> = 333, <i>p</i> &lt; 0.010. Correlations examined the association between WS and BN behaviours.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Upon consumption of milkshake versus control solution, WS positively associated with activation in the left caudate (<i>k</i> = 361, <i>p</i> = 0.001). WS also positively associated with binge eating (<i>r</i> = 0.52, <i>p</i> = 0.019), purging (<i>r</i> = 0.48, <i>p</i> = 0.032), and restraint (<i>r</i> = 0.53, <i>p</i> = 0.017). No BN behaviours associated with brain activation upon anticipation or consumption of milkshake (all <i>p</i>s &gt; 0.010).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Given the caudate's role in hedonic eating, the WS-caudate association may help maintain BN behaviours, such as binge eating. Although we failed to find an association between BN behaviours and caudate activation, our sample size was small. Therefore, we encourage replication in larger samples.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1370-1377"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147864738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Open Versus Concealed Weighing: Feasibility and Acceptability of a Pilot Study of Adults With Anorexia Nervosa in Residential Treatment","authors":"Kim Anderson,&nbsp;Dan Blalock,&nbsp;Casey Boldt,&nbsp;Alan Duffy,&nbsp;Phil Mehler,&nbsp;Renee Rienecke","doi":"10.1002/erv.70105","DOIUrl":"10.1002/erv.70105","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>This pilot study examined the feasibility and acceptability of conducting a comparative trial of open versus concealed weighing in a U.S. residential treatment programme for adults with anorexia nervosa (AN).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Thirty-four participants were assigned to either open (<i>n</i> = 18) or concealed (<i>n</i> = 16) weighing. Feasibility was assessed through recruitment and retention; acceptability was evaluated using patient-reported responses on a 14-item Patient Experience with Weighing (PEW) questionnaire. A single item measuring Fear of Knowing Weight (FKW) was used to examine how fear changed across weighing methods.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Recruitment was adequate in both conditions, though enrolment was higher in the open weighing arm (75% vs. 58%). No participants withdrew from the open group, whereas 54% of those in the concealed group discontinued. Both groups rated their weighing method as somewhat helpful. Reductions in FKW were significantly greater in the open weighing group (<i>b</i> = −2.57, <i>p</i> &lt; 0.01).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Findings indicate that a controlled comparison of weighing procedures is feasible in residential care for AN. While both methods were viewed as somewhat helpful, open weighing showed stronger associations with reduced fear of knowing weight. Familiarity with a weighing method may be an important factor to consider when introducing or changing weighing practices.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1165-1170"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147500164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"A Multi-Site Study of Brief Cognitive-Behavioural Therapy for Eating Disorders for Individuals With BMI ≥ 30","authors":"Ashley Dunford,&nbsp;P. Evelyna Kambanis,&nbsp;Lilian P. Palmer,&nbsp;Haley Graver,&nbsp;Megan E. Liu,&nbsp;Jordan Hillard,&nbsp;Stefania Yee,&nbsp;Hannah Turner,&nbsp;Lauren Breithaupt,&nbsp;Emma Evans,&nbsp;Ellen Blythe,&nbsp;Chloe White,&nbsp;Jade Broadley,&nbsp;Glenn Waller,&nbsp;Kamryn T. Eddy,&nbsp;Jennifer J. Thomas,&nbsp;Kendra R. Becker","doi":"10.1002/erv.70112","DOIUrl":"10.1002/erv.70112","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Cognitive-behavioural therapy (CBT) for eating disorders (EDs) has raised concerns of appropriateness for patients in higher-weight bodies. We evaluated acceptability (Sample 1—United States [USA]) and effectiveness (Sample 1—USA, Sample 2—United Kingdom [UK]) of CBT-T by body mass index [BMI] category. We hypothesised that individuals with BMI ≥ 30 kg/m² would be more likely to drop out and show smaller symptom reductions compared to participants with BMI &lt; 30 kg/m².</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Participants with non-underweight EDs (USA: <i>n</i> = 63; UK: <i>n</i> = 58) received CBT-T and completed the ED-15 to evaluate change in behaviours (objective binge eating, purging, restriction, excessive exercise) and cognitions (Eating Concern, Weight/Shape Concern, Global Score).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Contrary to hypotheses, CBT-T completion did not differ by BMI category. Participants demonstrated large and significant reductions in binge eating, excessive exercise, and ED cognitions, with no significant differences by BMI (USA, UK). Although the BMI ≥ 30 kg/m² group demonstrated significantly smaller reductions in restriction and purging (UK only), smaller reductions in the higher-weight group were fully explained by their significantly lower pre-treatment symptoms.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Results from this exploratory multisite study found no evidence that CBT-T was less acceptable or effective for participants in higher-weight bodies.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1209-1220"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147624325","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Long-Term Effectiveness of Inpatient and Day-Hospital Treatment of Eating Disorders in Departments of Psychosomatic Medicine and Psychotherapy in Germany","authors":"Magdalena Pape,&nbsp;Stephan Herpertz,&nbsp;Stephan Doering,&nbsp;Henrik Kessler,&nbsp;Martina de Zwaan,&nbsp;Almut Zeeck,&nbsp;Armin Hartmann,&nbsp;Tobias Hofmann,&nbsp;Matthias Rose,&nbsp;Katrin Imbierowicz,&nbsp;Franziska Geiser,&nbsp;Ilona Croy,&nbsp;Kerstin Weidner,&nbsp;Jörg Rademacher,&nbsp;Silke Michalek,&nbsp;Eva Morawa,&nbsp;Yesim Erim,&nbsp;Eva-Maria Skoda,&nbsp;Martin Teufel,&nbsp;Stanislav Heinzmann,&nbsp;Claas Lahmann,&nbsp;Eva Milena Johanne Peters,&nbsp;Johannes Kruse,&nbsp;Dirk von Boetticher,&nbsp;Christoph Herrmann-Lingen,&nbsp;Mariel Nöhre,&nbsp;Ulrike Dinger,&nbsp;Hans-Christoph Friederich,&nbsp;Alexander Niecke,&nbsp;Christian Albus,&nbsp;Rüdiger Zwerenz,&nbsp;Manfred Beutel,&nbsp;Casper Roenneberg,&nbsp;Peter Henningsen,&nbsp;Barbara Stein,&nbsp;Christiane Waller,&nbsp;Karsten Hake,&nbsp;Carsten Spitzer,&nbsp;Andreas Stengel,&nbsp;Stephan Zipfel,&nbsp;Katja Weimer,&nbsp;Harald Gündel,&nbsp;Aram Kehyayan","doi":"10.1002/erv.70114","DOIUrl":"10.1002/erv.70114","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>There is ample evidence on the efficacy of different therapeutic approaches in treating eating disorders. Yet, studies on the effectiveness of inpatient/day-hospital treatment of eating disorders are rare.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Data were retrieved from a naturalistic multi-center effectiveness study of inpatient and day-hospital treatment in departments of psychosomatic medicine and psychotherapy in Germany (MEPP). <i>N</i> = 151 patients with Anorexia Nervosa (AN) and atypical AN, as well as <i>n</i> = 120 patients with Bulimia Nervosa (BN) and atypical BN were included. Eating disorder pathology (EDE-Q) and BMI were assessed on admission, at discharge, and 1 year after discharge. Changes over time were analysed in both outcomes. Treatment success was assessed individually using reliable change (RC) indices. Regression analyses were used to identify predictors of RC.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>EDE-Q scores decreased in both patient groups. One year after discharge, RC was estimated in 33.8% of patients with AN and 43.3% of patients with BN. 24.2% of patients with AN and 54.3% with BN showed partial remission.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Results from this multi-center effectiveness study are comparable to those of former national and European studies. Based on the results of individual treatment success, recommendations for inpatient/day-hospital treatment can be derived.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>The study was registered at the German Clinical Trials Register (www.drks.de; ID: DRKS00016412)</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1273-1284"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70114","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147718290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Essential Training for an Essential Role: Dietitians and Eating Disorder Care","authors":"Caroline A. Hill,&nbsp;Tanja Rabbering,&nbsp;Kelly M. Dann,&nbsp;Jasmine K. Singh,&nbsp;Maureen Moerbeck,&nbsp;Sarah Maguire","doi":"10.1002/erv.70115","DOIUrl":"10.1002/erv.70115","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Aims</h3>\u0000 \u0000 <p>Dietitians are critical members of the multidisciplinary eating disorder treatment team. Dietitians frequently encounter clients with undiagnosed or undisclosed eating disorders; however, many graduate dietitians lack specialised eating disorder training. This study evaluates the effectiveness of the <i>Dietitian Essentials</i> eLearning program to increase dietitians' self-reported knowledge, skills, and confidence to treat clients with eating disorders.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Health professionals (<i>N</i> = 613) consented to participate in the evaluation between January 2019 and March 2025. Change in self-reported pre- and post-training knowledge, skills, confidence, and willingness to treat eating disorders were analysed using paired-sample <i>t</i>-tests (<i>N</i> = 438), and differences by remoteness of work setting and years of eating disorder clinical experience were assessed with repeated measures ANOVA. Feedback on program feasibility, acceptability, and most and least helpful aspects of the course were collected.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Participants were mostly dietitians working in generalist settings with less than 2 years of experience working with eating disorders, however 80% reported they were currently treating clients with eating disorders. Large post-training improvements (Cohen's <i>d</i> = 0.9–1.7) were observed across all learning outcomes, with the largest gains for treatment-specific knowledge and professional issues. Dietitians with the least eating disorder clinical experience showed the greatest improvements.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p><i>Dietitian Essentials</i> meets a critical workforce training gap for dietitians by providing dietitian-specific eating disorder training which is essential to safe clinical practice. Dietitians are often the first responders for eating disorder care−equipping community dietitians with core competencies may facilitate earlier identification and contribute to minimising harm and improving outcomes for this at-risk population.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1351-1359"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70115","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785710","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Leptin Reduces Running in a Rodent Anorexia Nervosa Model via a Distributed Neural Network","authors":"Nick J. M. Papavoine,&nbsp;Melissa N. Veendijk,&nbsp;Jessie Nijman,&nbsp;Mieneke C. M. Luijendijk,&nbsp;Inge G. Wolterink-Donselaar,&nbsp;Frank J. Meye,&nbsp;Roger A. H. Adan","doi":"10.1002/erv.70119","DOIUrl":"10.1002/erv.70119","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Hyperactivity is a persistent and clinically relevant symptom in anorexia nervosa (AN). Hyperactivity is inversely correlated with leptin levels. While systemic leptin administration attenuates hyperactivity in rodent models, the specific brain regions mediating this effect remain unclear. Leptin acts on different brain areas involved in energy expenditure and motivation, including the ventral tegmental area (VTA), substantia nigra (SN) and lateral hypothalamus (LH). The present study aimed to determine through which of these regions leptin mediates its suppressive effects on hyperactivity, reflected in rodent models as compulsive running, in the Activity-Based Anorexia (ABA) model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>To identify the neural substrates of leptin's behavioural effects, female Wistar rats were stereotactically cannulated targeting the VTA, SN, or LH. Animals were subjected to the ABA paradigm, and site-specific leptin (300 ng) or vehicle infusions were administered just before the onset of compulsive running. Running wheel activity (RWA), food intake, and body weight were assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Pooled analyses identified the SN, LH, and VTA as functionally relevant nodes where leptin administration significantly reduced compulsive running. While leptin also attenuated the compensatory increase in food intake across all three regions, the robust suppression of running compared to the more modest effects on feeding suggests a partial functional dissociation within this distributed network.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>These findings indicate that leptin modulates compulsive running and feeding through a distributed neural network rather than a single discrete locus. The identification of the SN and LH as novel targets for the suppression of compulsive running provides a first mapping of the neural substrates underlying leptin's regulation of hyperactivity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1314-1326"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, Implement, Sustain: Advancing Program-Led Interventions for Binge Eating, a Narrative Review","authors":"Bernou Melisse,&nbsp;Sanne F. W. Marcic-van Doornik,&nbsp;Annemarie van Elburg","doi":"10.1002/erv.70118","DOIUrl":"10.1002/erv.70118","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Most individuals with binge eating never receive treatment, partly due to a lack of specialists and long waitlists. Program-led interventions are scalable, and their therapeutic content and guidance are embedded within the program itself. However, they are not widely implemented in routine care. Strategies are proposed to overcome key barriers, to enhance the implementation, adherence, and reach of program-led interventions in routine care for binge eating.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Recent evidence from a structured keyword-based search on program-led interventions for recurrent binge eating is synthesised, and strategies are proposed to optimise their design, personalisation, and implementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Successful implementation of program-led interventions depends on intervention format, support, and user characteristics. Specialist-guided models reduce dropout rates, enhance adherence and acceptance, and support monitoring of adverse events. Brief, personalised digital interventions with synchronised therapist–user contact may reduce dropout probability and increase user and therapist adherence. Training and supervision promote therapist adherence and acceptance within routine care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Program-led interventions offer scalable, cost-effective care, but require balance between guidance, automation, contextual fit, and scalability. Challenges include resource demands, technological infrastructure, and applicability across diverse populations. Future research should test hybrid and algorithmically guided strategies, assess feasibility, equity, safeguard safety and privacy to support sustainable implementation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1238-1249"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Comorbid Psychopathology Symptoms as Predictors of Family Based Treatment for Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa in a Real-World Setting","authors":"Daniel Wilson,&nbsp;Hilary Grimmer,&nbsp;Renata A. Mendes,&nbsp;Jenna Irwin,&nbsp;Julie Atherton,&nbsp;Richard Litster,&nbsp;Jacinda White,&nbsp;Natalie J. Loxton","doi":"10.1002/erv.70124","DOIUrl":"10.1002/erv.70124","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>For adolescents with Anorexia Nervosa (AN) or Atypical Anorexia Nervosa (AAN), Family Based Treatment (FBT) is an effective treatment. However, outcomes remain suboptimal, making investigations into predictors of outcome important. Most prior research into FBT has focussed on parental and family factors as predictors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The current study aimed to identify predictors of FBT for adolescents with AN and AAN in a real-world setting, specifically focussed on comorbid patient psychopathology as a predictor of outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A prospective cohort of 135 young people engaging in manualised FBT (female = 92.6%, age = 14.33 years, SD = 1.54, range 11–17) at a public outpatient child and youth eating disorder (ED) service were evaluated. Measures of ED and comorbid psychopathology and BMI outcomes were evaluated pre- and post-treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Results showed that age was a predictor of drop-out and weight gain, with older age associated with higher chance of drop-out and less weight gain. No comorbid psychopathology measure predicted drop-out or treatment outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Findings highlight the potential role of age in treatment non-completion and weight regain in FBT, suggesting the potential need for developmental considerations to FBT among this group.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1360-1369"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70124","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}