Franziska Schutzeichel, Marije Aan Het Rot, Sanne F W van Doornik, Klaske A Glashouwer, Mirjam I Frey, Peter J de Jong
{"title":"A Meaning-Centered Intervention for Undergraduate Women With High Weight and Shape Concerns-Replication of a Randomized Controlled Trial.","authors":"Franziska Schutzeichel, Marije Aan Het Rot, Sanne F W van Doornik, Klaske A Glashouwer, Mirjam I Frey, Peter J de Jong","doi":"10.1002/erv.3175","DOIUrl":"https://doi.org/10.1002/erv.3175","url":null,"abstract":"<p><strong>Objective: </strong>Recent studies underscore the relevance of life meaning to the maintenance of eating disorders. A previously conducted randomized controlled trial tested a meaning-centered intervention for female university students with high weight and shape concerns. After a 6-week online intervention led by a trainer, participants in the intervention condition scored higher on life meaning and lower on eating disorder symptoms and general distress compared to a waitlist group.</p><p><strong>Method: </strong>Given that the original study took place during COVID-19, this study replicated the design to test the findings' robustness.</p><p><strong>Results: </strong>Compared to the waitlist condition (n = 68), participants in the intervention condition (n = 63) again scored higher on the presence of life meaning at post-assessment and follow-up. Participants in the intervention condition also showed moderately lower internalizing symptoms at both timepoints, whereas eating disorder symptoms were only reduced in those with relatively high baseline symptom severity.</p><p><strong>Conclusions: </strong>Thus, also without social distancing measures, the intervention increased life meaning and reduced eating disorder symptoms and comorbid internalizing symptoms in women with weight and shape concerns.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143067699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mauro Scala, Mariangela Tabone, Marco Paolini, Andrea Salueña, Rocío Arroyo Iturra, Veronica Romero Ferreiro, Miguel Ángel Alvarez-Mon, Alessandro Serretti, Maria Del Rocío Gonzalez Soltero, Roberto Rodriguez-Jimenez
{"title":"Unlocking the Link Between Gut Microbiota and Psychopathological Insights in Anorexia Nervosa: A Systematic Review.","authors":"Mauro Scala, Mariangela Tabone, Marco Paolini, Andrea Salueña, Rocío Arroyo Iturra, Veronica Romero Ferreiro, Miguel Ángel Alvarez-Mon, Alessandro Serretti, Maria Del Rocío Gonzalez Soltero, Roberto Rodriguez-Jimenez","doi":"10.1002/erv.3179","DOIUrl":"https://doi.org/10.1002/erv.3179","url":null,"abstract":"<p><strong>Objective: </strong>This systematic review explores the associations between qualitative/quantitative changes in gut microbiota and psychopathological symptoms or other clinical features in patients with eating disorders (EDs). Secondary outcomes include exploring gut microbiota changes in EDs and potential relationships with psychotropic drug use.</p><p><strong>Method: </strong>A systematic search was conducted across biomedical databases from inception to June 2024 according to PRISMA guidelines. The risk of bias was assessed, and a narrative synthesis was performed due to the heterogeneity of the outcomes.</p><p><strong>Results: </strong>Only findings related to anorexia nervosa (AN) were identified. Ten studies, of which seven were longitudinal, two cross-sectional, and one interventional (N = 350 patients with AN, and 304 HCs), were included. Despite no clear links between diversity metrics and clinical symptoms being observed, specific taxa belonging to phylum Firmicutes, such as Clostridium, Roseburia, Lactobacillus, Faecalibacterium, and Bifidobacterium belonging to Actinobacteriota correlated with ED psychopathology, including anxiety and depressive symptoms.</p><p><strong>Conclusions: </strong>Changes in microbiota were related to anxiety and depressive symptoms, as well as altered eating behaviours by modulating inflammation and insulin pathways through short-chain fatty acids (SCFAs), that also lead to neurotransmitter imbalances. Further studies are required to replicate these finding and to explore whether similar patterns are observed in other EDs.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068486","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Victoria Burmester, Emerie Sheridan, Nikita Catalina Julius, Jordan Elliott, Olivia Thackeray, Dasha Nicholls
{"title":"Oxytocin Amplifies Negative Response to Ambiguity in Adolescent Females With and Without Eating Disorders.","authors":"Victoria Burmester, Emerie Sheridan, Nikita Catalina Julius, Jordan Elliott, Olivia Thackeray, Dasha Nicholls","doi":"10.1002/erv.3167","DOIUrl":"https://doi.org/10.1002/erv.3167","url":null,"abstract":"<p><strong>Objective: </strong>Eating disorders (ED) typically emerge in adolescence, a critical period for brain development and peer bonding. Interpersonal difficulties-particularly social anxiety-frequently co-occur with ED. Oxytocin is a neuropeptide that modulates social cognition and linked to prosocial effects. To date, no study has investigated oxytocin's effects on negative interpretation bias toward ambiguous information in adolescents with ED.</p><p><strong>Methods: </strong>Forty-eight female adolescents aged 16 to 17 years with and without EDs took part in a placebo-controlled, double-blinded, randomised, crossover trial investigating the effects of 24 IU intranasal oxytocin on negative interpretations of ambiguous scenarios. Participants and controls were tested twice, approximately one week apart.</p><p><strong>Results: </strong>Contrary to hypothesis, oxytocin increased negative interpretations overall (p = 0.019, large effect). Adolescent females with AN or BN made more negative interpretations than controls when presented with ambiguous information. There was no group effect for those who reached or did not reach threshold on an autism screen.</p><p><strong>Conclusions: </strong>This study suggests adolescents with EDs interpret ambiguous information more negatively than controls and that oxytocin administration amplifies negative responses to ambiguity in adolescent females, including in controls. Research tools that effectively identify these biases would help to widen the scope of ED treatments for adolescents.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068473","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Wendy Spettigue, Stéphanie Drouin, Leanna Isserlin, Sasha Palmert, Clare Roscoe, Megan Harrison, Nuray Kanbur, Jacquie Bishop, Mark L Norris
{"title":"The Psychological, Cognitive, and Behavioural Effects of Starvation in Humans: A Scoping Review.","authors":"Wendy Spettigue, Stéphanie Drouin, Leanna Isserlin, Sasha Palmert, Clare Roscoe, Megan Harrison, Nuray Kanbur, Jacquie Bishop, Mark L Norris","doi":"10.1002/erv.3174","DOIUrl":"https://doi.org/10.1002/erv.3174","url":null,"abstract":"<p><strong>Background: </strong>Research has highlighted the physical complications of starvation, but there is less research examining the psychological effects of starvation in humans.</p><p><strong>Aims: </strong>This scoping review synthesises literature on the non-physical effects of starvation in humans.</p><p><strong>Method: </strong>Following PRISMA-ScR guidelines, we searched MEDLINE, PsycINFO, and Global Health for studies published between 1946 and 2023 examining the non-physical effects of starvation in individuals aged 2-79 years, including those who were starved, malnourished, stunted, wasted, underweight, had a restrictive eating disorder, or were raised in famine conditions.</p><p><strong>Results: </strong>From 16,555 abstracts, 851 articles on the effects of malnutrition were reviewed, and 318 were included. Among these, 35% focused on children and adolescents, 25.5% on adults with comorbid illnesses, 17% on older adults, 13% on those with eating disorders, 6% on adults without comorbidities, and 3.5% on famine survivors. Cognitive impairments were the most frequently reported effects in children. In adults and older adults, depression and anxiety were common, along with reduced cognitive functioning, reduced quality of life, social withdrawal, impaired sleep and impaired sexual functioning. Individuals with eating disorders experienced depression, anxiety, obsessive-compulsive symptoms, emotion regulation difficulties, and cognitive impairment.</p><p><strong>Conclusions: </strong>There is extensive evidence showing the detrimental non-physical consequences of starvation in children and adults. These findings should inform research, clinical interventions, and educational materials addressing the effects of insufficient nutrition, including in those with restrictive eating disorders.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-29","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143068483","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lauren Makin, Elisa Zesch, Adia Meyer, Valeria Mondelli, Kate Tchanturia
{"title":"Autism, ADHD, and Their Traits in Adults With Bulimia Nervosa and Binge Eating Disorder: A Scoping Review.","authors":"Lauren Makin, Elisa Zesch, Adia Meyer, Valeria Mondelli, Kate Tchanturia","doi":"10.1002/erv.3177","DOIUrl":"https://doi.org/10.1002/erv.3177","url":null,"abstract":"<p><strong>Objective: </strong>This review maps existing literature on the prevalence of autism and ADHD in adult patients with Bulimia Nervosa (BN) and Binge Eating Disorder (BED); patient and stakeholder perspectives on this comorbidity; clinical differences in this population; and potential treatment adaptations or adjunct therapies. This is with the aim to inform future research priorities to improve clinical practice.</p><p><strong>Method: </strong>As pre-registered, and following PRISMA guidelines, six databases (Embase, MEDLINE via Ovid, PsycINFO, Web of Science, CENTRAL, and Scopus) were searched for studies regarding autism and/or ADHD (diagnosed, probable, or traits) in adult patients with BN or BED. Screening and data extraction were conducted twice independently for each record.</p><p><strong>Results: </strong>Twenty-nine studies were included, with 25,416 participants, mostly women (69.3%). Thirteen prevalence studies suggested autism and ADHD are more common in BN or BED than non-ED populations. One study explored the expert perspectives on autism and ADHD in BED, while 15 studies considered treatment options, mainly medications.</p><p><strong>Conclusion: </strong>This review highlights a need for more research on the experiences, clinical differences, and non-medical treatment options for Autistic/ADHD patients with BN or BED. Findings suggest these conditions commonly co-occur but remain under-explored in terms of patient-centred interventions and clinical outcomes.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143047267","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Fiona Duffy, Imogen Peebles, Emma Clark, Rachel Loomes, Lisa Thomson, Ellen Maloney, Emy Nimbley
{"title":"Clinicians' Experiences of Eating Disorder Focused Family Therapy With Autistic Young People.","authors":"Fiona Duffy, Imogen Peebles, Emma Clark, Rachel Loomes, Lisa Thomson, Ellen Maloney, Emy Nimbley","doi":"10.1002/erv.3173","DOIUrl":"https://doi.org/10.1002/erv.3173","url":null,"abstract":"<p><strong>Objective: </strong>Eating disorder focused family therapy (FT-ED) is the leading outpatient intervention for adolescents with Anorexia Nervosa. Autistic people report poorer eating disorder treatment experiences and may be at increased risk of inpatient admissions. There is a need to consider adaptions to eating disorder treatment for this population. The aim of this study is to explore the experiences of clinicians in the delivery of FT-ED for Autistic young people with Anorexia Nervosa and any adaptations currently being implemented.</p><p><strong>Method: </strong>FT-ED trained clinicians who had experience of delivering this modality with young Autistic people and their families, were invited to take part in interviews. Transcripts were analysed using Reflexive Thematic Analysis.</p><p><strong>Results: </strong>Eleven clinicians completed interviews and analysis generated four themes and eight subthemes: (1) Systemic context, (2) Raising potential autism, (3) Autism eating disorders crossover, (4) Manual versus adaptations.</p><p><strong>Conclusions: </strong>This paper is the first exploration of clinician's experience delivering FT-ED to Autistic young people and their families and highlighted unique considerations with this population. It is an initial step to consider adaptations to the FT-ED model, with the aim of making eating disorder treatments more effective, accessible and acceptable for Autistic young people and their families.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Yu-Ping Wang, Min-Yi Chu, Yi Wang, Xiaoxia Lei, Qing Kang, Ling Yue, Yan Chen, Simon S Y Lui, Zhen Wang, Raymond C K Chan, Jue Chen
{"title":"Altered Sensorimotor Striatal Network Connectivity in Women With Anorexia Nervosa.","authors":"Yu-Ping Wang, Min-Yi Chu, Yi Wang, Xiaoxia Lei, Qing Kang, Ling Yue, Yan Chen, Simon S Y Lui, Zhen Wang, Raymond C K Chan, Jue Chen","doi":"10.1002/erv.3172","DOIUrl":"https://doi.org/10.1002/erv.3172","url":null,"abstract":"<p><strong>Objective: </strong>Anorexia nervosa (AN) is associated with disturbances in reward processing, cognitive control, and body image perception, implicating striatal dysfunction. Evidence suggests that underweight may modulate brain function in AN. We aimed to investigate whole-brain resting-state functional connectivity (rsFC) of the striatum in patients with AN while controlling for the acute effects of underweight.</p><p><strong>Method: </strong>Using theoretically selected striatal sub-regions, whole-brain rsFC patterns of the striatum were compared among patients with AN (n = 39, BMI = 16.19 ± 1.48 kg/m<sup>2</sup>), normal weight healthy controls (NHC) (n = 31, BMI = 20.98 ± 1.72 kg/m<sup>2</sup>), and underweight healthy controls (UHC) (n = 22, BMI = 16.68 ± 0.69 kg/m<sup>2</sup>). Correlation analysis between rsFC and clinical measures was conducted for the patients with AN.</p><p><strong>Results: </strong>Compared with the NHC group, AN patients showed increased striatal rsFC with the fronto-parietal network (FPN) and reduced striatal rsFC with sensorimotor and visual regions. Compared with the UHC group, AN patients exhibited reduced striatal rsFC solely with sensorimotor and visual regions. No significant correlations were found between striatal rsFC and clinical variables in the patients with AN.</p><p><strong>Conclusion: </strong>Our findings suggest that decreased striatal rsFC with sensorimotor and visual areas may represent illness-specific neural correlates in patients with AN.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143014228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Lena Maria Mayr, Nicole Besse-Flütsch, Lukasz Smigielski, Susanne Walitza, Dagmar Pauli
{"title":"Cost-Effectiveness Analysis of Family-Based Treatment With Additional Home Treatment for Adolescent Anorexia Nervosa.","authors":"Lena Maria Mayr, Nicole Besse-Flütsch, Lukasz Smigielski, Susanne Walitza, Dagmar Pauli","doi":"10.1002/erv.3170","DOIUrl":"https://doi.org/10.1002/erv.3170","url":null,"abstract":"<p><strong>Objective: </strong>Family-based treatment (FBT) is promising for treating adolescents with anorexia nervosa, but long-term remission rates are modest. Home treatment (HT) as a supplement to FBT aims to enhance sustainability and effectiveness by supporting recovery within the family. This study compares the cost-effectiveness of FBT alone versus FBT with additional HT for adolescents with anorexia nervosa.</p><p><strong>Method: </strong>This cost-effectiveness analysis is based on a non-randomized pilot study, which examined the effectiveness of HT for adolescents with anorexia nervosa, disregarding the financial aspects. HT involved therapeutic interventions delivered in the patient's home environment, while FBT involved structured therapy sessions at the psychiatric clinic. Data from 61 patients were analysed, with 40 receiving FBT + HT and 21 receiving FBT only. Costs included FBT sessions, HT sessions, and inpatient treatment. Effectiveness was measured by weight restoration at thresholds of expected body weight (EBW) > 85% and EBW > 95%.</p><p><strong>Results: </strong>FBT + HT promoted greater weight restoration within three months compared to FBT alone (70% vs. 52% at EBW > 85%; 38% vs. 29% at EBW > 95%). FBT + HT was more cost-effective, with lower average costs per patient meeting weight restoration criteria (8243 vs. 20,446 Swiss francs at EBW > 85%; 15,387 vs. 37,485 Swiss francs at EBW > 95%). Inpatient treatment accounted for most of the cost, with FBT + HT reducing hospitalisation needs.</p><p><strong>Conclusions: </strong>FBT with additional HT is a more cost-effective treatment for adolescents with anorexia nervosa. Although the cost-effectiveness index was relatively high, effective treatment could reduce the long-term burdens of this disorder. Larger long-term studies are needed to validate these findings and assess sustained cost-effectiveness.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142956699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emily Davey, Rachel Bryant-Waugh, Sophie D Bennett, Nadia Micali, Julian Baudinet, Anna Konstantellou, Sam Clark-Stone, Amelia Green, Roz Shafran
{"title":"Guided Self-Help Treatment for Children and Young People With Eating Disorders: A Proof-Of-Concept Pilot Study.","authors":"Emily Davey, Rachel Bryant-Waugh, Sophie D Bennett, Nadia Micali, Julian Baudinet, Anna Konstantellou, Sam Clark-Stone, Amelia Green, Roz Shafran","doi":"10.1002/erv.3171","DOIUrl":"https://doi.org/10.1002/erv.3171","url":null,"abstract":"<p><strong>Objective: </strong>To conduct a proof-of-concept pilot study of a CBT guided self-help intervention for children and young people with eating disorders.</p><p><strong>Method: </strong>Children and young people were recruited from two outpatient eating disorder services in England. They received a CBT guided self-help intervention consisting of eight modules and weekly support sessions. Clinical outcomes (eating disorder psychopathology and associated impairment, changes in %median BMI, depression, anxiety, and behavioural difficulties) were assessed at baseline and post-intervention (12 weeks). Qualitative data were collected for future intervention refinement.</p><p><strong>Results: </strong>Six female adolescents (aged 13-17) received the CBT guided self-help intervention. All participants completed a minimum of six modules and six support sessions. Quantitative and qualitative feedback suggested that the intervention was acceptable. From baseline to post-intervention, there was a reduction in eating disorder psychopathology and impairment, along with an increase in %median BMI. Outcomes for depression, anxiety and behavioural difficulties were mixed.</p><p><strong>Conclusions: </strong>The CBT guided self-help intervention was feasibly implemented, acceptable to participants, and showed potential to produce clinical benefits. While promising, these findings are preliminary and derived from a small, non-randomised sample of White female adolescents. More rigorous evaluation with a randomised design and a larger, representative sample is warranted.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142923740","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vishnupriya Khatri, Amy Stein, Philip S Mehler, Dennis Gibson
{"title":"Association of Phosphate Supplements With Refeeding Oedema in Restrictive Eating Disorders.","authors":"Vishnupriya Khatri, Amy Stein, Philip S Mehler, Dennis Gibson","doi":"10.1002/erv.3169","DOIUrl":"https://doi.org/10.1002/erv.3169","url":null,"abstract":"<p><strong>Objective: </strong>Refeeding oedema, believed to result from the effects of insulin on renal sodium retention and subsequent oedema formation, typically occurs during the first 2 weeks after reintroduction of nutrition in individuals with severe malnutrition and can intensify body image distress in patients with eating disorders (EDs). Phosphate supplements have been found to increase insulin sensitivity, and it is hypothesised that they may also contribute to refeeding oedema in patients with EDs.</p><p><strong>Method: </strong>In this retrospective cohort study of 633 patients with severe malnutrition due to anorexia nervosa (AN) or avoidant restrictive food intake disorder (ARFID), the impact of phosphate supplementation on the rate of weight gain was investigated.</p><p><strong>Results: </strong>39% of patients required treatment with phosphate supplements during their hospital course. Patients in the phosphate supplement group had significantly more weight gain than the cohort who did not receive a phosphate supplement (p < 0.05). The rate of weight gain also increased, in the phosphate supplement group, as admission body mass index decreased.</p><p><strong>Conclusions: </strong>This is the first study to suggest that crucial phosphate supplementation contributes to refeeding oedema in patients with EDs. Future studies should seek to better understand the relationship between phosphate supplementation and weight trends in order to optimise clinical management.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.9,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142915977","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}