Addressing Heterogeneity in Binge Eating Disorder: A Cluster Analysis Approach Based on Age of Onset, Clinical and Psychopathological Features.

IF 3.4 2区心理学 Q1 PSYCHIATRY

European Eating Disorders Review Pub Date : 2025-10-04 DOI:10.1002/erv.70034

Lucía Camacho-Barcia, Lia T Sánchez-Salido, Jessica Jiménez Del Toro, Roser Granero, Isabel Sánchez, Kim Supit, Nadia Micali, Katrin Elisabeth Giel, Susana Jiménez-Murcia, Stephan Zipfel, Fernando Fernández-Aranda

{"title":"Addressing Heterogeneity in Binge Eating Disorder: A Cluster Analysis Approach Based on Age of Onset, Clinical and Psychopathological Features.","authors":"Lucía Camacho-Barcia, Lia T Sánchez-Salido, Jessica Jiménez Del Toro, Roser Granero, Isabel Sánchez, Kim Supit, Nadia Micali, Katrin Elisabeth Giel, Susana Jiménez-Murcia, Stephan Zipfel, Fernando Fernández-Aranda","doi":"10.1002/erv.70034","DOIUrl":null,"url":null,"abstract":"Objective: This study investigates clinical heterogeneity in patients with binge eating disorder (BED) and its association with treatment outcomes.Methods: A two-step cluster analysis was conducted on a clinical sample of 196 BED patients, using an agglomerative hierarchical procedure based on both categorical and quantitative measures-psychopathological symptoms, personality traits, emotional dysregulation, body composition, and food addiction. A subsequent comparison between clusters assessed therapy outcomes.Results: Two distinct clusters emerged: C1 (n = 77) and C2 (n = 119). C2 patients exhibited a more dysfunctional profile, marked by more frequent binge episodes, higher eating psychopathology, greater emotion regulation difficulties, higher impulsivity levels, worse psychopathological state, higher food addiction levels, and personality traits reflecting greater harm avoidance and lower self-directedness and cooperativeness. While clusters did not differ by age, C2 had earlier age of onset and longer duration of the disorder. In contrast, C1 showed a more functional profile, later age of onset, lower total body fat mass, and better treatment outcomes.Conclusion: These findings highlight heterogeneity in BED, particularly regarding age of onset and associated clinical features, which may influence treatment response. The results suggest the need for distinct treatment strategies and more personalised therapeutic approaches tailored to patient subtypes.","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.4000,"publicationDate":"2025-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"European Eating Disorders Review","FirstCategoryId":"102","ListUrlMain":"https://doi.org/10.1002/erv.70034","RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"PSYCHIATRY","Score":null,"Total":0}

引用次数: 0

Abstract

Objective: This study investigates clinical heterogeneity in patients with binge eating disorder (BED) and its association with treatment outcomes.

Methods: A two-step cluster analysis was conducted on a clinical sample of 196 BED patients, using an agglomerative hierarchical procedure based on both categorical and quantitative measures-psychopathological symptoms, personality traits, emotional dysregulation, body composition, and food addiction. A subsequent comparison between clusters assessed therapy outcomes.

Results: Two distinct clusters emerged: C1 (n = 77) and C2 (n = 119). C2 patients exhibited a more dysfunctional profile, marked by more frequent binge episodes, higher eating psychopathology, greater emotion regulation difficulties, higher impulsivity levels, worse psychopathological state, higher food addiction levels, and personality traits reflecting greater harm avoidance and lower self-directedness and cooperativeness. While clusters did not differ by age, C2 had earlier age of onset and longer duration of the disorder. In contrast, C1 showed a more functional profile, later age of onset, lower total body fat mass, and better treatment outcomes.

Conclusion: These findings highlight heterogeneity in BED, particularly regarding age of onset and associated clinical features, which may influence treatment response. The results suggest the need for distinct treatment strategies and more personalised therapeutic approaches tailored to patient subtypes.

查看原文本刊更多论文

解决暴食症的异质性：基于发病年龄、临床和精神病理特征的聚类分析方法。

目的：本研究探讨暴食症（BED）患者的临床异质性及其与治疗结果的关系。方法：对196例BED患者的临床样本进行两步聚类分析，采用基于分类和定量测量-精神病理症状，人格特征，情绪失调，身体成分和食物成瘾的凝聚分层程序。随后的组间比较评估了治疗结果。结果：出现两个明显的簇：C1 （n = 77）和C2 （n = 119）。C2型患者表现出更严重的功能失调，暴食发作更频繁，饮食精神病理更高，情绪调节困难更大，冲动水平更高，精神病理状态更差，食物成瘾水平更高，人格特征反映出更大的伤害回避和更低的自我指导和合作。而集群没有年龄差异，C2有更早的发病年龄和更长的持续时间的障碍。相比之下，C1表现出更多的功能特征，发病年龄较晚，体脂质量较低，治疗效果较好。结论：这些发现强调了BED的异质性，特别是在发病年龄和相关临床特征方面，这可能会影响治疗反应。研究结果表明，需要针对患者亚型制定不同的治疗策略和更个性化的治疗方法。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文求助全文

来源期刊

European Eating Disorders Review PSYCHOLOGY, CLINICAL-

CiteScore

8.90

自引率

7.50%

发文量

期刊介绍： European Eating Disorders Review publishes authoritative and accessible articles, from all over the world, which review or report original research that has implications for the treatment and care of people with eating disorders, and articles which report innovations and experience in the clinical management of eating disorders. The journal focuses on implications for best practice in diagnosis and treatment. The journal also provides a forum for discussion of the causes and prevention of eating disorders, and related health policy. The aims of the journal are to offer a channel of communication between researchers, practitioners, administrators and policymakers who need to report and understand developments in the field of eating disorders.