European Eating Disorders Review最新文献

{"title":"Leptin Reduces Running in a Rodent Anorexia Nervosa Model via a Distributed Neural Network","authors":"Nick J. M. Papavoine,&nbsp;Melissa N. Veendijk,&nbsp;Jessie Nijman,&nbsp;Mieneke C. M. Luijendijk,&nbsp;Inge G. Wolterink-Donselaar,&nbsp;Frank J. Meye,&nbsp;Roger A. H. Adan","doi":"10.1002/erv.70119","DOIUrl":"10.1002/erv.70119","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Hyperactivity is a persistent and clinically relevant symptom in anorexia nervosa (AN). Hyperactivity is inversely correlated with leptin levels. While systemic leptin administration attenuates hyperactivity in rodent models, the specific brain regions mediating this effect remain unclear. Leptin acts on different brain areas involved in energy expenditure and motivation, including the ventral tegmental area (VTA), substantia nigra (SN) and lateral hypothalamus (LH). The present study aimed to determine through which of these regions leptin mediates its suppressive effects on hyperactivity, reflected in rodent models as compulsive running, in the Activity-Based Anorexia (ABA) model.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>To identify the neural substrates of leptin's behavioural effects, female Wistar rats were stereotactically cannulated targeting the VTA, SN, or LH. Animals were subjected to the ABA paradigm, and site-specific leptin (300 ng) or vehicle infusions were administered just before the onset of compulsive running. Running wheel activity (RWA), food intake, and body weight were assessed.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Pooled analyses identified the SN, LH, and VTA as functionally relevant nodes where leptin administration significantly reduced compulsive running. While leptin also attenuated the compensatory increase in food intake across all three regions, the robust suppression of running compared to the more modest effects on feeding suggests a partial functional dissociation within this distributed network.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>These findings indicate that leptin modulates compulsive running and feeding through a distributed neural network rather than a single discrete locus. The identification of the SN and LH as novel targets for the suppression of compulsive running provides a first mapping of the neural substrates underlying leptin's regulation of hyperactivity.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1314-1326"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70119","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Design, Implement, Sustain: Advancing Program-Led Interventions for Binge Eating, a Narrative Review","authors":"Bernou Melisse,&nbsp;Sanne F. W. Marcic-van Doornik,&nbsp;Annemarie van Elburg","doi":"10.1002/erv.70118","DOIUrl":"10.1002/erv.70118","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Most individuals with binge eating never receive treatment, partly due to a lack of specialists and long waitlists. Program-led interventions are scalable, and their therapeutic content and guidance are embedded within the program itself. However, they are not widely implemented in routine care. Strategies are proposed to overcome key barriers, to enhance the implementation, adherence, and reach of program-led interventions in routine care for binge eating.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Methods</h3>\u0000 \u0000 <p>Recent evidence from a structured keyword-based search on program-led interventions for recurrent binge eating is synthesised, and strategies are proposed to optimise their design, personalisation, and implementation.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Successful implementation of program-led interventions depends on intervention format, support, and user characteristics. Specialist-guided models reduce dropout rates, enhance adherence and acceptance, and support monitoring of adverse events. Brief, personalised digital interventions with synchronised therapist–user contact may reduce dropout probability and increase user and therapist adherence. Training and supervision promote therapist adherence and acceptance within routine care.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Program-led interventions offer scalable, cost-effective care, but require balance between guidance, automation, contextual fit, and scalability. Challenges include resource demands, technological infrastructure, and applicability across diverse populations. Future research should test hybrid and algorithmically guided strategies, assess feasibility, equity, safeguard safety and privacy to support sustainable implementation.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1238-1249"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70118","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147699438","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Comorbid Psychopathology Symptoms as Predictors of Family Based Treatment for Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa in a Real-World Setting","authors":"Daniel Wilson,&nbsp;Hilary Grimmer,&nbsp;Renata A. Mendes,&nbsp;Jenna Irwin,&nbsp;Julie Atherton,&nbsp;Richard Litster,&nbsp;Jacinda White,&nbsp;Natalie J. Loxton","doi":"10.1002/erv.70124","DOIUrl":"10.1002/erv.70124","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Background</h3>\u0000 \u0000 <p>For adolescents with Anorexia Nervosa (AN) or Atypical Anorexia Nervosa (AAN), Family Based Treatment (FBT) is an effective treatment. However, outcomes remain suboptimal, making investigations into predictors of outcome important. Most prior research into FBT has focussed on parental and family factors as predictors.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The current study aimed to identify predictors of FBT for adolescents with AN and AAN in a real-world setting, specifically focussed on comorbid patient psychopathology as a predictor of outcome.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A prospective cohort of 135 young people engaging in manualised FBT (female = 92.6%, age = 14.33 years, SD = 1.54, range 11–17) at a public outpatient child and youth eating disorder (ED) service were evaluated. Measures of ED and comorbid psychopathology and BMI outcomes were evaluated pre- and post-treatment.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Results showed that age was a predictor of drop-out and weight gain, with older age associated with higher chance of drop-out and less weight gain. No comorbid psychopathology measure predicted drop-out or treatment outcomes.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>Findings highlight the potential role of age in treatment non-completion and weight regain in FBT, suggesting the potential need for developmental considerations to FBT among this group.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1360-1369"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70124","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147822277","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Examining Facets of Body Image Disturbance Across Anorexia Nervosa Illness and Recovery Stages","authors":"Scarlett R. Croce,&nbsp;Amy C. Malcolm,&nbsp;Andrea Phillipou,&nbsp;Christina Ralph-Nearman","doi":"10.1002/erv.70103","DOIUrl":"10.1002/erv.70103","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Research suggests body image disturbance (BID) is a core feature of anorexia nervosa (AN), however, more research is required on how BID may differ across illness and recovery stages. This study aimed to investigate differences in BID facets (body image dissatisfaction and body image perception) among women with AN who were currently ill and at varying recovery stages, and women with no history of eating disorders (non-ED controls).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>One hundred ninety-nine women (18–65 years old) meeting criteria for either current AN (AN-C; <i>n</i> = 73), weight-restoration (AN-WR; <i>n</i> = 86), partial recovery (AN-PR; <i>n</i> = 19), or full recovery (AN-FR; <i>n</i> = 21), and a group of non-ED controls (<i>n</i> = 128), completed online self-report measures of BID and AN symptom severity.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>The AN-C and AN-WR showed significantly worse body image dissatisfaction and body image perception than the AN-FR and non-ED control groups.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Discussion</h3>\u0000 \u0000 <p>These findings suggest that BID differs across AN recovery stages and suggests that holistic recovery from AN includes the remediation of BID. The findings highlight the need for treatment to provide continuous support especially after the weight-restoration period when BID may be at its peak.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1184-1192"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70103","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147595667","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Assessing Clinical Severity and Prognosis in Adolescents With Anorexia Nervosa and Atypical Anorexia Nervosa Using the Albumin-Globulin Ratio","authors":"Eylem Şerife Kalkan,&nbsp;Ayşe Bilge Baklaci,&nbsp;Yelda Kiliç,&nbsp;Sinem Akgül,&nbsp;Nilgün Özgül,&nbsp;Melis Pehlivanturk Kizilkan","doi":"10.1002/erv.70106","DOIUrl":"10.1002/erv.70106","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>The albumin-globulin ratio (AGR) is a biochemical marker reflecting nutritional and inflammatory status, with significant prognostic value in chronic conditions. This study examined its association with clinical/biochemical markers in adolescents with anorexia nervosa (AN) and atypical AN (AAN).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>This retrospective study analysed data from 294 adolescents (103 AN, 191 AAN) aged 12–18 years, presented at an adolescent medicine clinic between 2016 and 2023. AGR values were calculated and relationship between AGR and markers of both disease severity (rate of weight loss, vital sign instability, amenorrhoea, hospitalisation need) and prognosis (rehospitalisation, menstrual recovery, achievement of target body weight) was evaluated. An ideal AGR cut-off of 1.84 was identified using receiver operating characteristic curve analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Mean AGR was higher in AN than AAN (1.85 ± 0.28 vs. 1.73 ± 0.31, <i>p</i> &lt; 0.001). AGR correlated negatively with body mass index <i>z</i>-score, blood pressure, and heart rate. AGR ≥ 1.84 was associated with amenorrhoea, hospitalisation need at admission, hypotension, bradycardia, hypothermia, and leucopenia. Higher AGR predicted rehospitalisation during follow-up and longer menstrual resumption duration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Unlike other chronic conditions, a higher AGR at presentation was associated with both greater medical disease severity and poorer prognosis in adolescents with AN and AAN, possibly due to relatively preserved albumin alongside decreased globulin.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1193-1208"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70106","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147619228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The Importance of Considering Personal Recovery for Eating Disorders","authors":"Andrew Allen,&nbsp;Maddison Tunstall,&nbsp;Catherine Houlihan,&nbsp;Kay Pozzebon,&nbsp;Daniel B. Fassnacht,&nbsp;Kathina Ali","doi":"10.1002/erv.70116","DOIUrl":"10.1002/erv.70116","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>Definitions of recovery from eating disorders (EDs) have traditionally emphasised symptom reduction and functional restoration. However, growing research highlights the importance of integrating personal recovery, defined by self-acceptance, autonomy, and psychological wellbeing. This study explored the relationship between partial clinical remission and personal recovery in individuals with lived experience of an ED.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>A total of 234 participants (<i>N</i> = 234; <i>M</i>_age = 28.10; 89.3% female; 49.6% non-heterosexual) were recruited online and completed measures assessing ED symptom severity, quality of life, and personal recovery. Criteria for partial clinical remission were based on established cut-offs for measures of ED symptomology. Personal recovery was defined by self-endorsement of a validated recovery framework.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Chi-square tests revealed that rates of personal recovery (52.1%) were significantly higher than rates of partial clinical remission (22.6%). While clinical remission increased the likelihood of personal recovery (OR = 6.46), many participants endorsed personal recovery despite not meeting clinical criteria. No significant differences in personal recovery were found between ED types or between heterosexual and non-heterosexual participants as an exploratory analysis.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>These findings underscore the importance of incorporating personal recovery constructs into ED assessment, treatment, and outcome monitoring.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1285-1293"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70116","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147785797","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Learning to Be Kind to Me: A Compassion-Focused Group for Adolescents With Anorexia Nervosa.","authors":"Talia Drew, Pamela Fox, Charlotte Waton, Isobel Hyatt, Julian Baudinet","doi":"10.1002/erv.70143","DOIUrl":"https://doi.org/10.1002/erv.70143","url":null,"abstract":"<p><strong>Background: </strong>Anorexia nervosa (AN) is often characterised by high levels of shame and self-criticism. Compassion-Focused Therapy (CFT) is a transdiagnostic intervention targeting these emotional vulnerabilities, yet its application in adolescent eating disorder services remains underexplored.</p><p><strong>Methods: </strong>This project examined a group-based CFT intervention delivered within an Intensive Day Treatment Programme at a specialist, outpatient child and adolescent eating disorder service. Quantitative outcomes were assessed using the Self-Compassion Scale (SCS) and Adolescent Shame-Proneness Scale (ASPS). Qualitative feedback was also collected and analysed using conversational content analysis.</p><p><strong>Results: </strong>Twenty-eight adolescents with restrictive eating disorders completed a brief CFT group between April 2024 and February 2025. Statistically significant improvements were observed in self-compassion (particularly reductions in uncompassionate self-responding) and subscales related to self-judgement, isolation, and over-identification (all p < 0.001). No significant changes were found in shame-proneness (p = 0.107). Qualitative analysis identified themes of increased emotional insight, reduced self-criticism, and appreciation for the group's sensory and reflective elements. Some participants reported challenges related to session length and the application of self-compassion in daily life.</p><p><strong>Conclusions: </strong>Findings suggest that CFT may enhance self-compassion in adolescents with AN and may serve as a valuable adjunct to existing treatment pathways. Further controlled trials are recommended to evaluate long-term outcomes and optimise integration into routine care.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148670881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Heart Rate Variability in Anorexia Nervosa: A Systematic Review and Meta-Analysis on the Moderating Role of Measurement Duration and Clinical Stage","authors":"Marta Victoria Santiago,&nbsp;Miguel Heres,&nbsp;Cristina Mazas,&nbsp;Maria Fernandez-del-Valle,&nbsp;Hugo Olmedillas,&nbsp;Susana Pulgar","doi":"10.1002/erv.70104","DOIUrl":"10.1002/erv.70104","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>To evaluate heart rate variability (HRV) as a biomarker of autonomic dysfunction in anorexia nervosa (AN), examining differences across clinical stages and the influence of HRV recording duration.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Quantitative studies comparing HRV parameters between individuals with AN and healthy controls were identified through a systematic search of six databases following PRISMA guidelines. Random-effects meta-analyses and meta-regressions were conducted, with HRV recording duration (5-min vs. 24-h recordings) examined as a moderator. Meta-regression by clinical stage was not feasible due to an insufficient number of studies. Risk of bias was assessed using the Joanna Briggs Institute tool, and certainty of evidence was rated with GRADE.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Nineteen studies were included, with 16 contributing to the meta-analysis (805 participants). Acute AN was associated with significantly lower heart rate (SMD = −1.807; 95% CI: [−3.36, −0.26]; <i>p</i> = 0.022) and reduced LF/HF ratio (SMD = −0.74; 95% CI: [−1.179, −0.301]; <i>p</i> &lt; 0.001). These results indicate parasympathetic predominance. Time-domain indices (SDNN and RMSSD) tended to be higher in AN but were not statistically significant and were supported by low-certainty evidence. Meta-regression analyses revealed that short-term (5-min) HRV recordings yielded significant differences for SDNN (SMD = 0.539; <i>p</i> = 0.008) and HF (SMD = 0.679; <i>p</i> = 0.037).</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusions</h3>\u0000 \u0000 <p>Overall, HRV reflects autonomic alterations in AN, particularly in the acute phase characterised by parasympathetic predominance. HRV does not consistently normalise during recovery. These findings are strongly moderated by recording duration. Short-term recordings show more consistent effects.</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1171-1183"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147505169","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Associations Between Baseline Severity and Treatment Effects in Digital Interventions for Eating Disorders: A Meta-Regression","authors":"Claudia Liu,&nbsp;Cleo Anderson,&nbsp;Mariel Messer,&nbsp;Jake Linardon","doi":"10.1002/erv.70113","DOIUrl":"10.1002/erv.70113","url":null,"abstract":"<div>\u0000 \u0000 \u0000 <section>\u0000 \u0000 <h3> Objective</h3>\u0000 \u0000 <p>While it is assumed that digital interventions are more suitable for milder eating disorder presentations, the evidence supporting this assumption remains unclear. We conducted meta-regressions testing whether baseline severity at the study level was associated with treatment effects from digital interventions for eating disorders.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Method</h3>\u0000 \u0000 <p>Databases were searched to identify RCTs of digital interventions compared to controls in individuals with diagnostic, subthreshold, or self-reported eating disorders. Baseline severity was operationalised as global levels of eating disorder psychopathology and objective binge eating. We conducted bivariable and multivariable meta-regressions to test whether baseline severity was associated with treatment versus control effect sizes and dropout.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Results</h3>\u0000 \u0000 <p>Thirty-one trials were included. Bivariable meta-regressions showed that higher average objective binge eating was associated with greater treatment effect sizes and lower dropout rates. These associations remained significant in most sensitivity analyses, but not in the multivariable meta-regressions. Average global eating disorder psychopathology levels at baseline were not associated with treatment effects in bivariable meta-regressions, but was significantly and positively associated with effects in the multivariable model that adjusted for other characteristics.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Conclusion</h3>\u0000 \u0000 <p>Higher baseline severity may not limit the effectiveness or acceptability of digital interventions and in some contexts be associated with larger effects.</p>\u0000 </section>\u0000 \u0000 <section>\u0000 \u0000 <h3> Trial Registration</h3>\u0000 \u0000 <p>https://osf.io/j9chm/overview</p>\u0000 </section>\u0000 </div>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":"34 5","pages":"1231-1237"},"PeriodicalIF":3.2,"publicationDate":"2026-08-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://onlinelibrary.wiley.com/doi/epdf/10.1002/erv.70113","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147646872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Preliminary Investigation of Effort Expenditure for Food and Monetary Rewards in Loss-of-Control Eating.","authors":"Sarah C Dolan, Emilia Espinoza Carrasco, Mun Yee Kwan, Emily Barkley-Levenson, Simar Singh, Erin E Reilly","doi":"10.1002/erv.70160","DOIUrl":"https://doi.org/10.1002/erv.70160","url":null,"abstract":"<p><strong>Background: </strong>Loss-of-control eating (LOCE) is present across multiple eating disorder (ED) diagnoses and is associated with greater eating pathology in the general population. Initial research suggests differences in motivation to approach rewards in individuals with LOCE, but few studies directly compare disorder-relevant and general rewards. The current study explored motivation for food and monetary rewards in women with and without LOCE.</p><p><strong>Methods: </strong>Undergraduate women with LOCE (n = 23) and no ED symptoms (n = 24) completed food and money versions of the Effort Expenditure for Rewards Task (EEfRT). On each trial, participants chose between a low-effort/low-reward task and a high-effort/high-reward task with varying levels of reward and probability.</p><p><strong>Results: </strong>Participants with LOCE showed greater effort exertion for money with medium (but not low or high) probability of receipt compared to controls. Participant groups did not differ in their performance on the food EEfRT.</p><p><strong>Conclusions: </strong>These results suggest that individuals with LOCE will work for a larger monetary reward with a lower probability of receipt compared to controls, indicating heightened motivation for non-food rewards. Future research should explore whether individuals with LOCE show alterations in other aspects of reward processing across stimuli to more precisely identify reward-related treatment targets.</p>","PeriodicalId":48117,"journal":{"name":"European Eating Disorders Review","volume":" ","pages":""},"PeriodicalIF":3.2,"publicationDate":"2026-07-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148649482","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":2,"RegionCategory":"心理学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}