Vagner Deuel de O Tavares, Felipe B Schuch, Gary Skinner, Thea Baker, Madeleine France-Ratcliffe, Geovan Menezes de Sousa, May Lynn Quan, Colleen Cuthbert, Megan Teychenne
{"title":"A systematic review and meta-analysis of multi-health behavior interventions to reduce common mental health symptoms in people living with and beyond cancer.","authors":"Vagner Deuel de O Tavares, Felipe B Schuch, Gary Skinner, Thea Baker, Madeleine France-Ratcliffe, Geovan Menezes de Sousa, May Lynn Quan, Colleen Cuthbert, Megan Teychenne","doi":"10.1080/07347332.2026.2747658","DOIUrl":"https://doi.org/10.1080/07347332.2026.2747658","url":null,"abstract":"<p><strong>Background: </strong>People living with and beyond cancer often report lower levels of physical activity, poorer sleep, and poorer diet quality, all of which may contribute to an increased risk of common mental health symptoms. This systematic review aimed to investigate the effects of multi-health behavior interventions designed to reduce common mental health symptoms in people living with and beyond cancer.</p><p><strong>Methods: </strong>This systematic review and meta-analyses followed PRISMA guidelines. The search, conducted up to July 2, 2025, included PubMed, Embase, Web of Science, PsycInfo, and PsyAPA, and grey literature. Multi-health behavior interventions (randomized and non-randomized trials) for people living with and beyond cancer, that targeted at least two behaviors (physical activity, diet, sleep, mindfulness) and assessed effects on common mental health outcomes (depression, anxiety, stress) were included.</p><p><strong>Results: </strong>A total of 22 studies (<i>n</i> = 2,191 participants, 77.5% female; mean age 55 years) were included. Multi-health behavior interventions demonstrated small but significant improvements in depression (<i>g</i> = 0.40, 95% CI [0.26,0.55], <i>p</i> < 0.001), anxiety (<i>g</i> = 0.33, 95% CI [0.22,0.45], <i>p</i> < 0.001), and stress (<i>g</i> = 0.26, 95% CI [0.09,0.43], <i>p</i> = 0.003). Effects were consistent across treatment phases, cancer types, intervention type (flexible interventions and structured programs), number of intervention components, and intervention duration, with all subgroups showing significant improvements in at least one mental health outcome.</p><p><strong>Conclusion: </strong>Multi-health behavior interventions are associated with small but significant improvements in common mental health symptoms among people living with and beyond cancer. However, given the limitations and variable certainty of the available evidence, further high-quality RCTs are needed to confirm these findings.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-32"},"PeriodicalIF":1.9,"publicationDate":"2026-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149229192","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Cancer workforce readiness to identify and respond to domestic abuse: A national survey and follow-up interviews.","authors":"Sandi Dheensa, Eleanor Hepworth, Helen Winter","doi":"10.1080/07347332.2026.2747648","DOIUrl":"https://doi.org/10.1080/07347332.2026.2747648","url":null,"abstract":"<p><strong>Purpose: </strong>Domestic abuse (DA) is a highly prevalent public health and health equity issue. We aimed to investigate cancer professionals' experiences of DA among patients and assess cancer workforce readiness to identify, respond to, and prevent DA.</p><p><strong>Methods: </strong>Cross-sectional survey (<i>n</i> = 343, mostly healthcare workers) and 15 follow-up interviews within an explanatory sequential mixed-methods design.</p><p><strong>Results: </strong>Most participants had encountered individuals affected by DA in the past three years. Participants often referred patients to cancer psychologists. Unique opportunities to respond to DA arose in the cancer pathway, including holistic psychosocial approaches to care. But alongside were unique challenges, including difficulties distinguishing DA from common emotional responses to cancer diagnoses. Inadequate training, policies, and private spaces for DA inquiry limited organizational readiness to respond.</p><p><strong>Conclusion: </strong>Carefully designed cancer-specific DA interventions are required to improve cancer professionals' confidence and knowledge to safely seize these unique opportunities to identify, respond to, and prevent DA.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-21"},"PeriodicalIF":1.9,"publicationDate":"2026-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149196538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Bridgette Thom, Camille R Murray, Michelle L Manning, Mindy Gellin, Neda R Padilla, Lisa P Spees, Arrianna Marie Planey, Kevin Pignone, Austin R Waters, Donald L Rosenstein, Stephanie B Wheeler
{"title":"Training financial navigators across diverse research settings: A systematic approach and preliminary findings.","authors":"Bridgette Thom, Camille R Murray, Michelle L Manning, Mindy Gellin, Neda R Padilla, Lisa P Spees, Arrianna Marie Planey, Kevin Pignone, Austin R Waters, Donald L Rosenstein, Stephanie B Wheeler","doi":"10.1080/07347332.2026.2728120","DOIUrl":"https://doi.org/10.1080/07347332.2026.2728120","url":null,"abstract":"<p><strong>Background: </strong>The negative clinical and psychosocial implications of financial toxicity are well-documented. Financial navigation (FN) offers a solution toward mitigation at the patient-level, but there is limited standardization for training of navigators.</p><p><strong>Methods: </strong>We describe the process of creating and implementing a standardized training program for navigators across 10 clinical sites for participation in a non-randomized Type II clinical trial of FN.</p><p><strong>Results: </strong>Thirty-two navigators completed 17 h of training that included both study-specific elements and the Financial Advocacy Bootcamp (Levels 1 and 2) offered online through the Association of Cancer Care Centers. At completion of training, participants reported high self-efficacy to engage in FN and high confidence around FN.</p><p><strong>Conclusions: </strong>Standardized training of oncology financial navigators is essential to ensuring fidelity in FN delivery.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-9"},"PeriodicalIF":1.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Kate M Kaufman, Eva L Darow, Jessica Quach, Cynthia A Gerhardt, H Gerry Taylor, Emily L Moscato
{"title":"A mixed methods examination of caregiver perspectives on the quality of life and executive functioning of young childhood cancer survivors.","authors":"Kate M Kaufman, Eva L Darow, Jessica Quach, Cynthia A Gerhardt, H Gerry Taylor, Emily L Moscato","doi":"10.1080/07347332.2026.2728117","DOIUrl":"https://doi.org/10.1080/07347332.2026.2728117","url":null,"abstract":"<p><strong>Purpose: </strong>Over two-thirds of childhood cancer survivors experience late effects. While young childhood cancer survivors (YCCS; diagnosed ≤ age 7) face the greatest developmental risk, research centers school-aged survivors. Using mixed methods, we aimed to characterize caregiver perspectives of YCCS' psychosocial and neurocognitive difficulties.</p><p><strong>Methods: </strong>Stratified sampling was conducted to recruit caregivers of 23 YCCS (currently aged 3-11). Twenty-nine caregivers completed surveys and a semi-structured interview to assess their child's health-related quality of life (HRQOL), executive function (EF), and other challenges.</p><p><strong>Results: </strong>Children were reported to face significant difficulty: 69% below normative HRQOL, 50% impaired EF, and 41% delayed or impacted schooling. Qualitatively, caregivers discussed children's strengths and psychosocial, physical, and developmental concerns. Generally, more challenges were reported in interviews than surveys.</p><p><strong>Conclusion: </strong>YCCS experience age-specific challenges that warrant tailored intervention. Current clinical measures may not capture all concerns, indicating that observations and interviews are useful in assessing need.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-20"},"PeriodicalIF":1.9,"publicationDate":"2026-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149185164","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Vagner Deuel de O Tavares, Winson Y Cheung, Colleen A Cuthbert
{"title":"Survival and mortality in adults with cancer and pre-existing mental illness across multimorbidity types: a decade of population-based data from Alberta, Canada.","authors":"Vagner Deuel de O Tavares, Winson Y Cheung, Colleen A Cuthbert","doi":"10.1080/07347332.2026.2744357","DOIUrl":"10.1080/07347332.2026.2744357","url":null,"abstract":"<p><strong>Background: </strong>Adults living with cancer and pre-existing mental illness (PMI) represent a particularly vulnerable population. This study examined whether multimorbidity protects against or increases mortality among adults with cancer and PMI.</p><p><strong>Methods: </strong>We used Alberta Health Services administrative data (<i>n</i> = 15,144), to identify adults with both PMI and cancer diagnosed between 2013-2022, including demographic, comorbidity, and cancer information. The analysis used Cox proportional hazard models (HR) to evaluate the impact among different multimorbidity categories on all-cause mortality. The multimorbidity categories were classified as cardiometabolic (e.g. cardiovascular disease), musculoskeletal (e.g. rheumatic disease), chronic airway (e.g. chronic pulmonary disease), and general multimorbidity (e.g. including liver and renal disease). Multimorbidity combinations were defined as the presence of conditions across two or more categories.</p><p><strong>Results: </strong>In a cohort of 15,144 adults with cancer, 39.1% died during follow-up. In the overall cohort, compared with those without multimorbidity, adjusted models showed that multimorbidity increased mortality for cardiometabolic conditions (HR = 1.25, 95%CI 1.13-1.37), chronic airway disease (HR = 1.88, 95%CI 1.69-2.08), general multimorbidity (HR = 1.90, 95%CI 1.59-2.27), and multimorbidity combinations (HR = 2.29, 95%CI 2.08-2.51). Musculoskeletal conditions were not significant. By PMI subtype, multimorbidity combinations were consistently associated with increased mortality across mood, anxiety, substance use, and multiple psychiatric disorders (HRs = 1.67-1.91). General multimorbidity was associated with increased mortality in anxiety, substance use, and multiple psychiatric disorders (HRs = 1.72-2.74), whereas chronic airway disease was significant only in mood disorders. Cardiometabolic and musculoskeletal conditions were not associated with mortality after adjustment.</p><p><strong>Conclusions: </strong>Different multimorbidity categories are associated with increased mortality among adults with cancer and PMI. These findings underscore the importance of jointly considering psychiatric and physical health comorbidities in cancer care.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-20"},"PeriodicalIF":1.9,"publicationDate":"2026-10-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149170978","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Shanoo Sheikh, Deeba Nazir, Rajnish Raj, Khalid Bashir, Zaid Ahmad Wani, Mushood Ghulam Nabi
{"title":"Between hope and hardship: Lived experiences and quality of life among cancer patients in Kashmir.","authors":"Shanoo Sheikh, Deeba Nazir, Rajnish Raj, Khalid Bashir, Zaid Ahmad Wani, Mushood Ghulam Nabi","doi":"10.1080/07347332.2026.2744881","DOIUrl":"https://doi.org/10.1080/07347332.2026.2744881","url":null,"abstract":"<p><strong>Objective: </strong>Cancer is a leading cause of mortality worldwide and imposes significant psychosocial burdens. Beyond physical illness, patients experience psychological distress, anxiety, depression, and social isolation, particularly during active treatment. In Kashmir, cultural factors such as stigma, religious values, and gender norms strongly influence illness perception and coping; however, qualitative studies exploring lived experiences during treatment remain limited. This study aimed to explore the lived experiences, quality of life, and coping mechanisms of cancer patients in Kashmir during active treatment.</p><p><strong>Methods: </strong>A qualitative study using Interpretative Phenomenological Analysis (IPA) was conducted in July 2025 at radiation oncology department. Twenty adult inpatients with cancer were recruited purposively. In-depth, face-to-face interviews were conducted in Urdu or Kashmiri using open-ended guides. Data were audio-recorded, transcribed, translated, and analyzed following IPA principles. Researcher reflexivity and analytic memos were employed to enhance rigor.</p><p><strong>Results: </strong>The mean age of participants was 58.15 ± 17.08 years, with breast cancer being the most common diagnosis (30%). Through an iterative and interpretative analytic process, we identified five major themes and fifteen subthemes: family as both support and a source of silence or detachment; pervasive psychological distress, including anxiety, depression, and insomnia; spirituality as a key coping mechanism; social isolation and altered interpersonal relationships; and uncertainty regarding treatment and prognosis. These findings reflect the complex interplay of familial, psychological, spiritual, and social dimensions shaping patient experiences during treatment.</p><p><strong>Conclusion: </strong>Cancer patients in Kashmir experience multidimensional challenges influenced by cultural and social contexts. Culturally sensitive psycho-oncology interventions that address psychological distress, family dynamics, and spiritual coping are essential to improve quality of life.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-19"},"PeriodicalIF":1.9,"publicationDate":"2026-10-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149167979","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Catherine Wilsnack, Qi Chen, Yaritza Carmona, Halena Rios, Farya Phillips, Barbara L Jones
{"title":"Reconstructing the cancer journey: The impact of adolescent and young adult (AYA) patient advisory boards on survivor experiences and advocacy.","authors":"Catherine Wilsnack, Qi Chen, Yaritza Carmona, Halena Rios, Farya Phillips, Barbara L Jones","doi":"10.1080/07347332.2026.2737256","DOIUrl":"https://doi.org/10.1080/07347332.2026.2737256","url":null,"abstract":"<p><strong>Purpose: </strong>The purpose of this study was to explore how serving on a patient advisory board shaped experiences on cancer journeys for Adolescent and Young Adult (AYA) cancer survivors.</p><p><strong>Methods: </strong>Data was collected from 15 participants who served on the AYA patient advisory boards at the University of Texas Health Austin Livestrong Cancer Institute (LCI) and MD Anderson Cancer Center. Participants completed in-depth, semi-structured interviews <i>via</i> Zoom. Narrative thematic analysis was used to analyze transcribed, de-identified interviews.</p><p><strong>Findings: </strong>Major themes emerged from the data related to advisory boards facilitating emotional and social connection, advocacy for self and others, and collaborative projects at each cancer center. The patient advisory board served as a mode for participants to find meaning out of their cancer diagnosis and experience serving on the advisory board.</p><p><strong>Conclusion: </strong>Findings suggest AYA patient advisory boards are not only beneficial for providers and healthcare systems, but also for patients.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-17"},"PeriodicalIF":1.9,"publicationDate":"2026-10-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149116712","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jithin T K, Garima Nirmal, K G Gopakumar, Nilaa M P, Jisha Abraham, Maya Padmanabhan
{"title":"Parental expectations at the time of childhood cancer diagnosis: Development and pilot testing of a structured assessment tool in India.","authors":"Jithin T K, Garima Nirmal, K G Gopakumar, Nilaa M P, Jisha Abraham, Maya Padmanabhan","doi":"10.1080/07347332.2026.2737248","DOIUrl":"https://doi.org/10.1080/07347332.2026.2737248","url":null,"abstract":"<p><strong>Background: </strong>Parents of children newly diagnosed with cancer develop expectations about treatment, support, and financial challenges, influencing coping and communication. Validated tools to measure these expectations in low- and middle-income settings are limited.</p><p><strong>Methods: </strong>This cross-sectional pilot study was conducted in a pediatric oncology center in India. A 20-item, expert-validated questionnaire covering five domains-Treatment and Prognosis, Facility Support, Financial Support, Psychosocial Support, and Spiritual Support-was administered to 30 parents of children under 14 years at diagnosis. Items were rated on a 4-point Likert scale (1 = Unlikely, 2 = Less likely, 3 = Likely, 4 = More likely), with higher mean scores indicating more positive expectations. Descriptive statistics and nonparametric tests were used for analysis.</p><p><strong>Results: </strong>Overall expectations were high, with a mean score of 3.55 ± 0.21 on a 1-4 scale, indicating responses clustered between \"Likely\" and \"More likely.\" Facility Support (3.73 ± 0.27) and Treatment and Prognosis (3.64 ± 0.21) scored highest; Financial Support scored lowest (3.16 ± 0.40). Higher education (<i>p</i> = 0.022) and socioeconomic class (<i>p</i> < 0.05) predicted higher expectations. Younger child age correlated with psychosocial expectations (<i>ρ</i> = -0.68, <i>p</i> < 0.001).</p><p><strong>Conclusion: </strong>The tool demonstrated good feasibility and contextual relevance in this pilot study and may guide targeted psychosocial and financial support.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-14"},"PeriodicalIF":1.9,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Emma G Balkind, Kimberly A Arditte Hall, Christopher M McGrory, Gabrielle I Liverant, Yan Ma, Elyse R Park, Daniel L Hall
{"title":"Cancer survivors' sleep outcomes across cognitive behavioral therapy for insomnia.","authors":"Emma G Balkind, Kimberly A Arditte Hall, Christopher M McGrory, Gabrielle I Liverant, Yan Ma, Elyse R Park, Daniel L Hall","doi":"10.1080/07347332.2026.2706132","DOIUrl":"10.1080/07347332.2026.2706132","url":null,"abstract":"<p><strong>Background: </strong>Insomnia is a frequent and distressing concern for cancer survivors and is often associated with increased risk for depression and anxiety. Although cognitive behavioral therapy for insomnia (CBT-I) has been established as an effective treatment, brief, virtually delivered CBT-I with content targeted to survivorship may be more feasible and acceptable for cancer survivors. However, daily trajectories of change in key sleep parameters over the course of a brief, virtual CBT-I intervention have not been fully characterized in this population.it is not yet known how cancer survivors' insomnia changes over the course of a brief, virtual CBT-I intervention.</p><p><strong>Objective: </strong>This secondary analysis aimed to explore daily patterns in sleep diary metrics during the intervention phase of a virtually delivered CBT-I program for cancer survivors.</p><p><strong>Methods: </strong>Adult survivors (<i>N</i> = 20) treated for non-metastatic cancer with Insomnia Disorder (DSM-5 criteria and Insomnia Severity Index score ≥ 15) who were randomized to receive four 45-minute weekly sessions of interventionist-led CBT-I. Participants completed daily assessments to measure their total sleep time (TST), time in bed (TIB), sleep efficiency (SE), sleep onset latency (SOL), waking after sleep onset (WASO), and overall sleep quality (SQ). Linear mixed models were used to examine the trajectory of change in each sleep metric between sessions 1 and 4 (i.e. 21 days).</p><p><strong>Results: </strong>Across sleep metrics, linear growth models demonstrated better model fit than either quadratic or cubic growth models. Significant improvement was observed for SQ, SE, and SOL, but not TST, TIB, or WASO.</p><p><strong>Conclusions: </strong>Our findings illustrate significant linear change in several key sleep metrics across 4 sessions of virtually delivered CBT-I. Although preliminary, these findings, provide support for all 4 sessions as necessary and may inform decisions around optimal delivery of brief, virtual CBT-I in cancer survivors.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-9"},"PeriodicalIF":1.9,"publicationDate":"2026-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"149065111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Siyi Chen, Wenqian Zhao, Lanhua Ma, Li Liu, Lulu Li
{"title":"The reliability and validity of the Chinese version of the comprehensive assessment of acceptance and commitment therapy processes in individuals with nasopharyngeal carcinoma: A cross-sectional study.","authors":"Siyi Chen, Wenqian Zhao, Lanhua Ma, Li Liu, Lulu Li","doi":"10.1080/07347332.2026.2731453","DOIUrl":"https://doi.org/10.1080/07347332.2026.2731453","url":null,"abstract":"<p><strong>Objectives: </strong>The increasing application of Acceptance and Commitment Therapy (ACT) in oncology suggests that psychological flexibility may be a crucial factor in the treatment of individuals with cancer, rehabilitation and well-being. The Chinese version of the Comprehensive Assessment of Acceptance and Commitment Therapy Processes (CompACT-C) was found to have acceptable reliability and validity among individuals with breast cancer; however, its psychometric properties have not been verified among individuals with nasopharyngeal carcinoma (NPC).</p><p><strong>Methods: </strong>Convenience sampling was used to recruit participants diagnosed with NPC from a Grade III Level A hospital in Guangdong Province, China. The patients provided general demographic data and completed the CompACT-C and the Acceptance and Action Questionnaire-II (AAQ-II). The construct validity of the CompACT-C was tested using confirmatory factor analysis based on its original three-factor structure, and its internal consistency and 2-week test-retest reliability were evaluated. Convergent validity was determined by analyzing the correlation between the CompACT-C and AAQ-II.</p><p><strong>Results: </strong>A total of 310 individuals with NPC (age: 47.88 ± 11.45 years) completed the questionnaire and were included in the data analysis. The majority of patients (75.2%) were male. The three-factor structure of the CompACT-C initially showed a poor model fit (RMSEA = 0.073, CFI = 0.766, SRMR = 0.109). After removing items OE5, OE8, and OE9 and modifying item OE7 (reassignment from the \"Openness to Experience\" to the \"Behavioural Awareness\" dimension), the fit improved [structural equation modeling results: χ<sup>2</sup> = 338.999, <i>df</i> = 167, NC (χ<sup>2</sup>/<i>df</i>) = 2.030, RMSEA = 0.048, CFI = 0.918, TLI = 0.906, SRMR = 0.071]. The scale demonstrated satisfactory internal consistency (Cronbach's α = 0.780) and convergent validity with the AAQ-II (<i>r</i> = -0.570, <i>p</i> < 0.001) in this sample of individuals with NPC.</p><p><strong>Conclusions: </strong>The CompACT-C demonstrated acceptable reliability and validity for assessing psychological flexibility in individuals with NPC, supporting its use as an assessment instrument in future research.</p>","PeriodicalId":47451,"journal":{"name":"Journal of Psychosocial Oncology","volume":" ","pages":"1-22"},"PeriodicalIF":1.9,"publicationDate":"2026-09-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148957009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}