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Association between physical activity levels and lower urinary tract symptoms: a cohort study in 20,732 Brazilian men. 体育活动水平与下尿路症状之间的关系:一项针对20,732名巴西男性的队列研究
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024AO1204
Rafael Mathias Pitta, Oskar Kaufmann, Raphael Mendes Ritti-Dias, Luana de Lima Queiroga, Nelson Wolosker
{"title":"Association between physical activity levels and lower urinary tract symptoms: a cohort study in 20,732 Brazilian men.","authors":"Rafael Mathias Pitta, Oskar Kaufmann, Raphael Mendes Ritti-Dias, Luana de Lima Queiroga, Nelson Wolosker","doi":"10.31744/einstein_journal/2024AO1204","DOIUrl":"10.31744/einstein_journal/2024AO1204","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to evaluate the association between physical activity levels and lower urinary tract symptoms in 20,732 Brazilian men.</p><p><strong>Methods: </strong>This cohort study included 20,732 men of ≥40 years of age, who participated in health screening between January 2008 and December 2018. Standardized health data (anthropometric, laboratory, clinical, and lifestyle data) were collected. A logistic regression model was used to examine associations based on the occurrence of lower urinary tract symptoms.</p><p><strong>Results: </strong>Depressive symptoms (p<0.001), age (p<0.001), erectile dysfunction (p<0.001), and total prostate-specific antigens (p<0.001) were associated with higher odds of lower urinary tract symptoms in men, after adjusting the other factors. However, physical activity levels were associated with lower odds of developing lower urinary tract symptoms (low active, p<0.001; active, p=0.002; and high active, p=0.005).</p><p><strong>Conclusion: </strong>All physical activity levels were associated with lower odds of lower urinary tract symptoms in 20,732 Brazilian men.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eAO1204"},"PeriodicalIF":1.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634376/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856225","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Beyond the rare: a case of pseudomyogenic hemangioendothelioma treated sequentially with everolimus, denosumab, and pazopanib. 罕见之外:假性血管内皮瘤1例,依维莫司,地单抗和帕唑帕尼治疗顺序。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024RC1107
Douglas Dias E Silva, Camila Bobato Lara Gismondi, Murilo Marques Almeida Silva, Renee Zon Filipi, Fernando Moura, Reynaldo Jesus-Garcia, Roberto Carmagnani Pestana
{"title":"Beyond the rare: a case of pseudomyogenic hemangioendothelioma treated sequentially with everolimus, denosumab, and pazopanib.","authors":"Douglas Dias E Silva, Camila Bobato Lara Gismondi, Murilo Marques Almeida Silva, Renee Zon Filipi, Fernando Moura, Reynaldo Jesus-Garcia, Roberto Carmagnani Pestana","doi":"10.31744/einstein_journal/2024RC1107","DOIUrl":"10.31744/einstein_journal/2024RC1107","url":null,"abstract":"<p><p>Pseudomyogenic hemangioendothelioma is an ultra-rare vascular sarcoma that most commonly affects young adults, with a male predominance. It is diagnosed using a combination of imaging studies, histopathological examinations, and immunohistochemical staining. Surgical excision is the mainstay of treatment for pseudomyogenic hemangioendothelioma, with the goal of achieving a wide local excision and reducing the risk of recurrence. The role of systemic therapies is not well established because of the rarity of pseudomyogenic hemangioendothelioma, uncertainty regarding its response to currently approved medications, and lack of randomized controlled trials. We describe the case of an 18-year-old male patient diagnosed with multifocal pseudomyogenic hemangioendothelioma of the left lower limb who was treated with everolimus in addition to denosumab, achieving a partial response that was consolidated with resection, radiofrequency ablation, and radiotherapy of multiple local lesions, achieving a long-lasting response. Following subsequent disease progression, the patient responded favorably to pazopanib, with no significant toxicities.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eRC1107"},"PeriodicalIF":1.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634370/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Frailty over the rainbow: a cross-sectional study of LGBT+ adults aged over 50 years. 彩虹之上的脆弱:一项针对50岁以上LGBT+成年人的横断面研究。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024AO0937
Leonardo Rabelo de Melo, Milton Roberto Furst Crenitte, Richard Green, Wilson Jacob Filho, Thiago Junqueira Avelino-Silva
{"title":"Frailty over the rainbow: a cross-sectional study of LGBT+ adults aged over 50 years.","authors":"Leonardo Rabelo de Melo, Milton Roberto Furst Crenitte, Richard Green, Wilson Jacob Filho, Thiago Junqueira Avelino-Silva","doi":"10.31744/einstein_journal/2024AO0937","DOIUrl":"10.31744/einstein_journal/2024AO0937","url":null,"abstract":"<p><strong>Objective: </strong>To investigate differences in the prevalence of frailty between LGBT+ and non-LGBT+ older adults.</p><p><strong>Methods: </strong>A cross-sectional study involving Brazilians aged 50 and over was performed. The participants were invited to participate in an anonymous online survey between August 2019 and January 2020. The survey was widely distributed in neighborhood associations, day centers, non-governmental organizations, and social media. Those who identified as homosexual, bisexual, pansexual, non-heterosexual, transgender, travesti, or non-binary were grouped as LGBT+. Participants who were both cisgender and heterosexual were categorized as non-LGBT+. Frailty was measured using the FRAIL scale, and the participants were categorized as robust, prefrail, or frail. Generalized ordered logistic models were used to examine the adjusted association between LGBT+ status and frailty according to age and sex.</p><p><strong>Results: </strong>The study sample included 6,693 participants with a median age of 60 years. Overall, 1,332 patients were LGBT+ (19.9%), and 5,361 were non-LGBT+ (80.1%). Pre-frailty or frailty was observed in 656 (49%) LGBT+ participants and 2,460 (46%) non-LGBT+ participants (p=0.03). Multivariate analyses showed that being LGBT+ was independently associated with frailty in female participants aged ≥50 years (OR=1.52, 95%CI=1.08-2.13, p=0.02) and male participants aged ≥60 years (OR=2.83, 95%CI=1.41-5.69, p=0.004). Non-cisgender participants were also more likely to be frail than cisgender participants (OR=2.21, 95%CI=1.42-3.42, p<0.001).</p><p><strong>Conclusion: </strong>LGBT+ status was independently associated with frailty in female adults aged >50 years and males aged > 60 years. More research in this area and inclusive government policies are needed to promote the healthy aging of the LGBT+ population.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eAO0937"},"PeriodicalIF":1.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855689","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Percutaneous radiofrequency ablation of an actively bleeding renal angiomyolipoma. 活动性出血肾血管平滑肌脂肪瘤的经皮射频消融术。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024RC1008
Pedro Ivo Ravizzini, Henrique Augusto Lino, Gregory Ravizzini, Luís Gustavo Morato de Toledo
{"title":"Percutaneous radiofrequency ablation of an actively bleeding renal angiomyolipoma.","authors":"Pedro Ivo Ravizzini, Henrique Augusto Lino, Gregory Ravizzini, Luís Gustavo Morato de Toledo","doi":"10.31744/einstein_journal/2024RC1008","DOIUrl":"10.31744/einstein_journal/2024RC1008","url":null,"abstract":"<p><p>We report a case of computed tomography-guided percutaneous radiofrequency ablation of a bleeding renal angiomyolipoma. Radiofrequency ablation was performed as an alternative to partial nephrectomy and super-selective renal artery embolization for ruptured renal angiomyolipoma with slow persistent bleeding in a patient with elevated serum creatinine levels and other comorbidities. Computed tomography-guided radiofrequency ablation successfully stopped the active hemorrhage and did not affect long-term renal function during the 3-year follow period. No complications were associated with the procedure. Radiofrequency ablation of a bleeding renal angiomyolipoma may be considered a more invasive surrogate procedure in an urgent setting; however, further studies are necessary to evaluate the long-term benefits of this approach and its overall impact on renal function compared to traditional methods.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eRC1008"},"PeriodicalIF":1.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634353/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855695","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Use of convalescent plasma in COVID-19 treatment: is clinical severity more important than the intervention? 恢复期血浆在COVID-19治疗中的应用:临床严重程度比干预更重要吗?
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-16 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024AO0563
Valéria de Freitas Dutra, Heitor Duarte de Andrade, Viviane Regina Hernandez Nunes, Gabriella Mafra Elia, Juliane Roberta Dias Torres, Carolina Bonet Bub, Ana Paula Hitomi Yokoyama, José Mauro Kutner
{"title":"Use of convalescent plasma in COVID-19 treatment: is clinical severity more important than the intervention?","authors":"Valéria de Freitas Dutra, Heitor Duarte de Andrade, Viviane Regina Hernandez Nunes, Gabriella Mafra Elia, Juliane Roberta Dias Torres, Carolina Bonet Bub, Ana Paula Hitomi Yokoyama, José Mauro Kutner","doi":"10.31744/einstein_journal/2024AO0563","DOIUrl":"10.31744/einstein_journal/2024AO0563","url":null,"abstract":"<p><strong>Objective: </strong>This study compared the outcomes of two cohorts of patients with coronavirus disease 2019 (COVID-19) who received COVID-19 convalescent plasma transfusions between 2020 and 2021.</p><p><strong>Methods: </strong>This retrospective study was conducted at a tertiary hospital in São Paulo, Brazil. We included a retrospective cohort of patients who received convalescent compassionate plasma, and another group of patients from a previous clinical study. We collected clinical and laboratory data on the day of and 5 days after transfusion. Patients with hematological or immunological conditions were excluded. Statistical significance was set at p<0.05.</p><p><strong>Results: </strong>COVID-19 convalescent plasma did not affect the outcomes of patients with severe COVID-19 when comparing the two cohorts transfused with different volumes and titers of neutralizing antibodies. Despite improvements in some laboratory parameters, no effect on clinical outcomes was observed. Dialysis negatively affected the length of intensive care unit stay, hospitalization, and mechanical ventilation use. Each higher point on the day 0 World Health Organization scale reduced the probability of hospital and intensive care unit discharge and the risk of mechanical ventilation discontinuation.</p><p><strong>Conclusion: </strong>Dialysis and the assessed clinical severity represented by the World Health Organization scale on day 0 influenced the outcomes, whereas COVID-19 convalescent plasma transfusion did not.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eAO0563"},"PeriodicalIF":1.1,"publicationDate":"2024-12-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634348/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855904","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Average direct cost of peripherally inserted central catheterization by nurses in hospitalized patients: a cost estimate. 住院患者护士外周中心置管的平均直接成本:成本估算。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024GS0982
Maithê Gomes Lima Zandonadi, Danielly Negrão Guassú Nogueira, Amanda Salles Margatho do Nascimento, Paula Buck de Oliveira Ruiz, Natália Marciano de Araújo Ferreira, Suellen Karina de Oliveira Giroti, Flávia Meneguetti Pieri
{"title":"Average direct cost of peripherally inserted central catheterization by nurses in hospitalized patients: a cost estimate.","authors":"Maithê Gomes Lima Zandonadi, Danielly Negrão Guassú Nogueira, Amanda Salles Margatho do Nascimento, Paula Buck de Oliveira Ruiz, Natália Marciano de Araújo Ferreira, Suellen Karina de Oliveira Giroti, Flávia Meneguetti Pieri","doi":"10.31744/einstein_journal/2024GS0982","DOIUrl":"10.31744/einstein_journal/2024GS0982","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to estimate the direct costs of peripherally inserted central catheterization by nurses for hospitalized patients.</p><p><strong>Methods: </strong>A cost estimation study using a quantitative approach was conducted in a public teaching hospital in northern Paraná to calculate the direct costs of peripherally inserted central catheterization. The population included all medical records of patients between 15 and 99 years of age who were hospitalized and underwent peripherally inserted central catheterization by nurses between January 1, 2019, and December 31, 2021, totaling 664 insertions. The sample comprised 631 insertions.</p><p><strong>Results: </strong>The catheter kits (epicutaneous catheter + introducer + angulators) corresponded to the items with the highest unit costs and the greatest impact on the composition of costs. The cost of peripherally inserted central catheterization was US$ 217.14 (SD=75.21), with the cost of materials and staff's labor being US$ 195.39 (SD=74.15) and US$ 20.00 (SD=2.22), respectively.</p><p><strong>Conclusion: </strong>Materials represented the highest cost, which was explained by the high unit cost of catheters and kits used in echocardiography, followed by the staff's labor costs. The estimated average direct cost allowed for financial visibility of the inputs used. The key challenge is promoting lasting changes in the behavior of managers who carry out administrative functions in healthcare institutions, where proper budget management directly affects the allocative efficiency of resources and the quality of care.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eGS0982"},"PeriodicalIF":1.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634330/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856231","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Chronic spontaneous non-aneurysmal aortic rupture treated with endovascular surgery. 血管内手术治疗慢性自发性非动脉瘤性主动脉破裂。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024RC1113
Bruno Jeronimo Ponte, Viviane Galli Dib, Andressa Cristina Sposato Louzada, Júlia Freire Castanheiras de Paiva Ferreira, Lucas Lembrança Pinheiro, Cynthia de Almeida Mendes, Nelson Wolosker
{"title":"Chronic spontaneous non-aneurysmal aortic rupture treated with endovascular surgery.","authors":"Bruno Jeronimo Ponte, Viviane Galli Dib, Andressa Cristina Sposato Louzada, Júlia Freire Castanheiras de Paiva Ferreira, Lucas Lembrança Pinheiro, Cynthia de Almeida Mendes, Nelson Wolosker","doi":"10.31744/einstein_journal/2024RC1113","DOIUrl":"10.31744/einstein_journal/2024RC1113","url":null,"abstract":"<p><p>Spontaneous non-aneurysmal aortic rupture is rare and is usually attributed to penetrating aortic ulcers, infections, tumor infiltrations, or inflammatory and collagen diseases. Chronic rupture is infrequent but extremely rare in non-aneurysmal aortas, which makes diagnosis difficult because the absence of an aneurysm can mislead the physician to rule out rupture. Here, we describe the case of an 85-year-old male, who was undergoing oncological investigation for weight loss, inappetence, and back pain. Computed tomography and magnetic resonance imaging performed 3 months before admission showed a contained pseudoaneurysm of the infrarenal aorta associated with significant aortoiliac calcification and images suggestive of peritoneal implants. The patient was referred to our oncological center and underwent abdominal computed tomography for oncological investigation and staging. The patient was urgently admitted to the intensive care unit after a critical finding of contained rupture of the infrarenal aorta during the scan. Endovascular repair was indicated, and the patient was successfully treated with implantation of an Endurant IIs 25 × 25 × 70 mm endoprosthesis. No procedural complications were observed. Postoperative course was uneventful, and the patient was discharged on the fifth postoperative day. Control computed tomography performed 1 and 6 months after surgery showed no leaks. This case emphasizes the importance of communication between the radiologists and attending physicians. As the rupture was punctual and well defined in the computed tomography and angiography images, endovascular repair with an aortic cuff was safely performed, and the procedure time was reduced.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eRC1113"},"PeriodicalIF":1.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634351/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Point-of-care ultrasonography for diagnosis of purulent pericarditis postappendectomy: a case report. 急诊超声诊断阑尾切除术后化脓性心包炎1例。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024RC0962
José Alexandre Neto, Emanuel Pinheiro Esposito, Marcus Gomes Bastos, Cenilde da Costa Araújo, Luan Moraes Ferreira, Apollo Vinícius Fernandes Neves
{"title":"Point-of-care ultrasonography for diagnosis of purulent pericarditis postappendectomy: a case report.","authors":"José Alexandre Neto, Emanuel Pinheiro Esposito, Marcus Gomes Bastos, Cenilde da Costa Araújo, Luan Moraes Ferreira, Apollo Vinícius Fernandes Neves","doi":"10.31744/einstein_journal/2024RC0962","DOIUrl":"10.31744/einstein_journal/2024RC0962","url":null,"abstract":"<p><p>Purulent pericarditis is rare condition in the modern era of antibiotics. However, it is a serious condition as it has an accelerated progression and is difficult to diagnose due to its nonspecific clinical presentation, resulting in high mortality. Herein, we present a case in which a 36-year-old male patient with otherwise unremarkable medical history developed abdominal sepsis complicated by purulent pericarditis post-appendectomy. While the initial clinical presentation was not compatible with the classic signs of purulent pericarditis, the diagnosis was made using electrocardiography (ST elevation/PR depression) and point-of-care ultrasonography (pericardial effusion). The condition was successfully managed with pericardial drainage and broad-spectrum antibiotics. The present case reinforces and reiterates the need for high diagnostic suspicion and careful clinical reasoning in the diagnosis of purulent pericarditis. Furthermore, it highlights the applicability of point-of-care ultrasonography in the diagnosis of the same.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eRC0962"},"PeriodicalIF":1.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634327/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855708","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cavernous hemangioma in the masticatory space. 咀嚼间隙海绵状血管瘤。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024RC1106
Marina Nahas Dafico Bernardes, Lucas da Silva Braz, Júlia Ramos de Melo, Cárita Lopes Macêdo, Jordanna Ferreira Lousek, Hugo Fernandes de Paula, Hugo Valter Lisboa Ramos, Claudiney Candido Costa
{"title":"Cavernous hemangioma in the masticatory space.","authors":"Marina Nahas Dafico Bernardes, Lucas da Silva Braz, Júlia Ramos de Melo, Cárita Lopes Macêdo, Jordanna Ferreira Lousek, Hugo Fernandes de Paula, Hugo Valter Lisboa Ramos, Claudiney Candido Costa","doi":"10.31744/einstein_journal/2024RC1106","DOIUrl":"10.31744/einstein_journal/2024RC1106","url":null,"abstract":"<p><p>Hemangiomas are benign congenital vascular tumors that commonly arise in the head and neck regions. Although they present with indolent growth and involution in most cases, they can cause facial deformities. Hemangiomas have three subtypes: capillary, cavernous, and mixed. The cavernous type is most commonly observed on the lateral wall of the nose or the inferior turbinate. This report describes a case of cavernous hemangioma diagnosed in a rare location in the left retromaxillary masticatory space in a 67-year-old woman. Total excision of the lesion was performed with surgical treatment through the Caldwell-Luc access. Anatomopathological and immunohistochemical examinations suggested a malformative vascular lesion with a cavernous hemangioma pattern and without signs of malignancy.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eRC1106"},"PeriodicalIF":1.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634369/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142856247","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Tranexamic acid for reducing blood loss in bipolar transurethral resection of the prostate: a systematic review of literature. 氨甲环酸在双极经尿道前列腺切除术中减少失血:文献系统回顾。
IF 1.1
Einstein-Sao Paulo Pub Date : 2024-12-13 eCollection Date: 2024-01-01 DOI: 10.31744/einstein_journal/2024RW0734
Jonathan Doyun Cha, Gabriel Franco de Camargo Galindo, Caroline Vidalli Denser, Carlos Henrique Alves da Silva, Arie Carneiro
{"title":"Tranexamic acid for reducing blood loss in bipolar transurethral resection of the prostate: a systematic review of literature.","authors":"Jonathan Doyun Cha, Gabriel Franco de Camargo Galindo, Caroline Vidalli Denser, Carlos Henrique Alves da Silva, Arie Carneiro","doi":"10.31744/einstein_journal/2024RW0734","DOIUrl":"10.31744/einstein_journal/2024RW0734","url":null,"abstract":"<p><strong>Objective: </strong>To study the efficacy of tranexamic acid at reducing bleeding during bipolar prostate resection surgery (B-TURP) in patients with benign prostatic hyperplasia.</p><p><strong>Methods: </strong>We searched registers with MESH terms \"prostate hyperplasia,\" \"prostate surgery,\" and \"tranexamic acid.\" Studies available in full and online, published from 2013 to 2023, in Portuguese, English, Spanish, and French were included; review articles were excluded. Information sources: Portal Regional da Biblioteca Virtual em Saúde and PubMed Central. The Cochrane RoB2 tool was used to analyze risk of bias in randomized clinical trials.</p><p><strong>Results: </strong>Two randomized clinical trials involving 256 patients were included. Both groups had minimal risk of bias. Both studies showed a positive effect of tranexamic acid on blood loss parameters. Only one study in the tranexamic acid group had a lower transfusion rate, and another had a lower irrigation fluid volume and operation time in the tranexamic acid group. A meta-analysis was not performed because of the limited number of eligible studies.</p><p><strong>Conclusion: </strong>For patients undergoing B-TURP for benign prostatic hyperplasia symptoms, the use of tranexamic acid reduced blood loss. However, a limited number of patients were studied, and the available randomized clinical trials presented conflicting conclusions. Therefore, further studies are needed to explore this aspect in detail.</p><p><strong>Prospero database registration: </strong>(www.crd.york.ac.uk/prospero) under registration ID CRD42023416383.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"22 ","pages":"eRW0734"},"PeriodicalIF":1.1,"publicationDate":"2024-12-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11634347/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142855880","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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