拒绝国家移植中心提供的器官的结果和原因分析。

IF 0.9 Q2 MEDICINE, GENERAL & INTERNAL
Einstein-Sao Paulo Pub Date : 2025-08-18 eCollection Date: 2025-01-01 DOI:10.31744/einstein_journal/2025AO1598
Patricia Freire, Carmelia Matos Santiago Reis, Maria Rita Carvalho Garbi Novaes
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引用次数: 0

摘要

背景:本研究分析了向巴西国家移植中心提供的22,824个器官。其中,37%被接受,63%被拒绝。在接受的器官中,移植率为76%。了解拒绝的原因可能有助于改善国家器官的使用,并指导制定有效的策略。背景:在单一的国家等待名单中,后勤因素不是大多数器官排斥的原因。背景:拒签信息与操作者有关,因为拒签的原因在大多数情况下是通用的。背景:通过更详细地研究拒绝的原因,将更多的器官转化为移植,有可能增加对国家移植中心提供的器官的使用。目的:探讨由国家移植中心管理的单一国家器官清单中拒绝器官的结果和原因。方法:采用定量方法进行回顾性队列研究,使用的数据来自各州和联邦区未使用的器官,但提供给国家移植中心用于全国分布。结果:在美国向国家移植中心提供的22,824例未使用器官中,8,483例(37%)被接受,14,341例(63%)被拒绝。在接受的器官中,6433个(76%)被移植,2050个(24%)未被使用。结论:州际(国家)间器官使用水平有待提高,明确拒绝原因有助于制定干预策略。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Analysis of outcomes and reasons for refusing organs offered by the National Transplant Center.

Background: This study analyzed 22,824 organ offers made to Brazil's National Transplant Center. Of these, 37% were accepted and 63% were refused. Among the accepted organs, 76% were transplanted. Understanding reasons for refusal may help improve national organ use and guide the developmentof effective strategies.

Background: Logistical factors were not responsible for most organ rejections in the single national waiting list.

Background: Refusal information was operator dependent, as the reason for refusal was generic in most cases.

Background: It is possible to increase the use of organs offered to the National Transplant Center by converting more offers into transplants performed through a more detailed study of the reasons for refusal.

Objective: To investigate the outcomes and reasons for the refusal of organs offered on a single national list managed by the National Transplant Center.

Methods: This retrospective cohort study was conducted with a quantitative approach, using data from offers of organs not used in the states and the Federal District, but offered to the National Transplant Center for national distribution.

Results: Of the 22,824 offers of unused organs in the states to the National Transplant Center, 8,483 (37%) were accepted and 14,341 (63%) refused. Of the accepted organs, 6,433 (76%) were implanted and 2,050 (24%) were not used.

Conclusion: The use of organs at the interstate (national) level could be improved, and ascertaining the reasons for refusal could contribute to intervention strategies.

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Einstein-Sao Paulo
Einstein-Sao Paulo MEDICINE, GENERAL & INTERNAL-
CiteScore
2.00
自引率
0.00%
发文量
210
审稿时长
38 weeks
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