Patricia Freire, Carmelia Matos Santiago Reis, Maria Rita Carvalho Garbi Novaes
{"title":"拒绝国家移植中心提供的器官的结果和原因分析。","authors":"Patricia Freire, Carmelia Matos Santiago Reis, Maria Rita Carvalho Garbi Novaes","doi":"10.31744/einstein_journal/2025AO1598","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>This study analyzed 22,824 organ offers made to Brazil's National Transplant Center. Of these, 37% were accepted and 63% were refused. Among the accepted organs, 76% were transplanted. Understanding reasons for refusal may help improve national organ use and guide the developmentof effective strategies.</p><p><strong>Background: </strong>Logistical factors were not responsible for most organ rejections in the single national waiting list.</p><p><strong>Background: </strong>Refusal information was operator dependent, as the reason for refusal was generic in most cases.</p><p><strong>Background: </strong>It is possible to increase the use of organs offered to the National Transplant Center by converting more offers into transplants performed through a more detailed study of the reasons for refusal.</p><p><strong>Objective: </strong>To investigate the outcomes and reasons for the refusal of organs offered on a single national list managed by the National Transplant Center.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted with a quantitative approach, using data from offers of organs not used in the states and the Federal District, but offered to the National Transplant Center for national distribution.</p><p><strong>Results: </strong>Of the 22,824 offers of unused organs in the states to the National Transplant Center, 8,483 (37%) were accepted and 14,341 (63%) refused. Of the accepted organs, 6,433 (76%) were implanted and 2,050 (24%) were not used.</p><p><strong>Conclusion: </strong>The use of organs at the interstate (national) level could be improved, and ascertaining the reasons for refusal could contribute to intervention strategies.</p>","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"23 ","pages":"eAO1598"},"PeriodicalIF":0.9000,"publicationDate":"2025-08-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Analysis of outcomes and reasons for refusing organs offered by the National Transplant Center.\",\"authors\":\"Patricia Freire, Carmelia Matos Santiago Reis, Maria Rita Carvalho Garbi Novaes\",\"doi\":\"10.31744/einstein_journal/2025AO1598\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>This study analyzed 22,824 organ offers made to Brazil's National Transplant Center. Of these, 37% were accepted and 63% were refused. Among the accepted organs, 76% were transplanted. Understanding reasons for refusal may help improve national organ use and guide the developmentof effective strategies.</p><p><strong>Background: </strong>Logistical factors were not responsible for most organ rejections in the single national waiting list.</p><p><strong>Background: </strong>Refusal information was operator dependent, as the reason for refusal was generic in most cases.</p><p><strong>Background: </strong>It is possible to increase the use of organs offered to the National Transplant Center by converting more offers into transplants performed through a more detailed study of the reasons for refusal.</p><p><strong>Objective: </strong>To investigate the outcomes and reasons for the refusal of organs offered on a single national list managed by the National Transplant Center.</p><p><strong>Methods: </strong>This retrospective cohort study was conducted with a quantitative approach, using data from offers of organs not used in the states and the Federal District, but offered to the National Transplant Center for national distribution.</p><p><strong>Results: </strong>Of the 22,824 offers of unused organs in the states to the National Transplant Center, 8,483 (37%) were accepted and 14,341 (63%) refused. Of the accepted organs, 6,433 (76%) were implanted and 2,050 (24%) were not used.</p><p><strong>Conclusion: </strong>The use of organs at the interstate (national) level could be improved, and ascertaining the reasons for refusal could contribute to intervention strategies.</p>\",\"PeriodicalId\":47359,\"journal\":{\"name\":\"Einstein-Sao Paulo\",\"volume\":\"23 \",\"pages\":\"eAO1598\"},\"PeriodicalIF\":0.9000,\"publicationDate\":\"2025-08-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Einstein-Sao Paulo\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31744/einstein_journal/2025AO1598\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2025/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Einstein-Sao Paulo","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31744/einstein_journal/2025AO1598","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2025/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
Analysis of outcomes and reasons for refusing organs offered by the National Transplant Center.
Background: This study analyzed 22,824 organ offers made to Brazil's National Transplant Center. Of these, 37% were accepted and 63% were refused. Among the accepted organs, 76% were transplanted. Understanding reasons for refusal may help improve national organ use and guide the developmentof effective strategies.
Background: Logistical factors were not responsible for most organ rejections in the single national waiting list.
Background: Refusal information was operator dependent, as the reason for refusal was generic in most cases.
Background: It is possible to increase the use of organs offered to the National Transplant Center by converting more offers into transplants performed through a more detailed study of the reasons for refusal.
Objective: To investigate the outcomes and reasons for the refusal of organs offered on a single national list managed by the National Transplant Center.
Methods: This retrospective cohort study was conducted with a quantitative approach, using data from offers of organs not used in the states and the Federal District, but offered to the National Transplant Center for national distribution.
Results: Of the 22,824 offers of unused organs in the states to the National Transplant Center, 8,483 (37%) were accepted and 14,341 (63%) refused. Of the accepted organs, 6,433 (76%) were implanted and 2,050 (24%) were not used.
Conclusion: The use of organs at the interstate (national) level could be improved, and ascertaining the reasons for refusal could contribute to intervention strategies.