Einstein-Sao Paulo最新文献_第10页

Refractory late-onset cerebrospinal fluid fistula following mammoplasty: case report of a rare complication. 乳房成形术后难治性迟发性脑脊液瘘：一例罕见并发症报告。

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Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025RC1610

Clara Sanches Bueno, Eduardo Carvalhal Ribas, Eduardo Noda Kihara Filho, Andre Felix Gentil, Arthur Werner Poetscher

引用次数: 0

Raynaud's phenomenon during treatment with lisdexamfetamine: risk of cerebral vasospasm? 利地安非他明治疗期间的雷诺现象：脑血管痉挛的危险？

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Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025RC1439

Rubens Pitliuk, Tatyanny Paula Pinto da Costa Santos Fucci

{"title":"Raynaud's phenomenon during treatment with lisdexamfetamine: risk of cerebral vasospasm?","authors":"Rubens Pitliuk, Tatyanny Paula Pinto da Costa Santos Fucci","doi":"10.31744/einstein_journal/2025RC1439","DOIUrl":"10.31744/einstein_journal/2025RC1439","url":null,"abstract":"Lisdexamfetamine, a prodrug used to treat Attention Deficit/Hyperactivity Disorder in children, adolescents, and adults, is an inactive substance that is converted into its active form (dextroamphetamine) after being metabolized. This conversion primarily occurs in the bloodstream through enzymatic cleavage following active absorption from the gastrointestinal lumen. The active metabolite then stimulates the central nervous system by increasing the levels of dopamine and norepinephrine in the brain. It was discovered in 1996 by New River Pharmaceuticals and approved by the FDA in 2007 for the treatment of Attention Deficit/Hyperactivity Disorder in children. In this article, two cases of secondary Raynaud's phenomenon due to the use of lisdexamfetamine are described. Raynaud's disease is the primary form, occurring in the absence of an underlying cause, and differs from secondary Raynaud's phenomenon, which is associated with various medical conditions and pharmacological agents. In the cases reported in this study, the phenomenon occurred during treatment with lisdexamfetamine, where it is listed as an uncommon adverse effect in the prescribing information. In both patients presented in this report, discontinuation of the medication led to resolution of the phenomenon within a few days. This report highlights the fact that one of the patients reported episodes of dizziness during Raynaud's phenomenon, drawing attention to the potential associated complications.","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"23 ","pages":"eRC1439"},"PeriodicalIF":0.9,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12539819/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145558145","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Vicarious contrast media excretion: the bloody effusion Doppelgänger. 代入造影剂排泄：血性积液Doppelgänger。

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Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025AI1383

Danilo de Oliveira Santana Ramos, André Vaz, Eduardo Kaiser Ururahy Nunes Fonseca

引用次数: 0

Shifts in COVID-19 mortality throughout pandemic: a five-year analysis of healthcare responses. 大流行期间COVID-19死亡率的变化：对卫生保健应对措施的五年分析

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Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025CE1751

Camilla Mattiuzzi, Giuseppe Lippi

引用次数: 0

Analysis of acquisition and retention of cardiopulmonary resuscitation skills according to training frequency. 不同训练频次心肺复苏技能习得与保留情况分析。

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Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025AO1257

Joyce Kelly Barreto Silva, Thomaz Bittencourt Couto, Andreia Melo Coriolano, Alex Aquino, Júlio Cesar Martins Monte

{"title":"Analysis of acquisition and retention of cardiopulmonary resuscitation skills according to training frequency.","authors":"Joyce Kelly Barreto Silva, Thomaz Bittencourt Couto, Andreia Melo Coriolano, Alex Aquino, Júlio Cesar Martins Monte","doi":"10.31744/einstein_journal/2025AO1257","DOIUrl":"10.31744/einstein_journal/2025AO1257","url":null,"abstract":"Objective: To analyze cardiopulmonary resuscitation skill acquisition and retention at 3 and 6-month intervals and determine the optimal training frequency and associated costs.Methods: Fifth and sixth-year medical students practiced cardiopulmonary resuscitation using a feedback-equipped simulator.Results: The study included 43 students. Training with a feedback-equipped device significantly improved the performance compared to baseline: overall performance (median=95% [87-98%] versus 60% [18-89%]; p<0.001), compression depth (median=71% [24-92%] versus 13% [0-94%]; p<0.001), and compression rate (median=89% [71-98%] versus 69% [23-96%]; p=0.002. No significant differences were observed in the total recoil (median=93% [78-99%] versus 93% [58-100%]; p=0.991) or hand position (median=99% [100-100%] versus 99% [100-100%]; p=0.754). Over time, the overall performance increased by 12% at 3 months (mean ratio [MR]=1.12; p=0.001) and 10.1% at 6 months (MR=1.101; p<0.001). The compression depth improved by 38.9% at 3 months (MR=1.389; p<0.001) and 24.7% at 6 months (MR=1.247; p=0.010), whereas the compression rate increased only at 6 months (MR=1.086; p=0.026). No significant differences were found between the groups trained every 3 months and those trained every 6 months (p>0.05).Conclusion: Short-term training with a cardiopulmonary resuscitation feedback-equipped simulator significantly improved cardiopulmonary resuscitation skill acquisition and retention. However, no differences were observed between the 3- and 6-month training intervals, suggesting that a 6-month interval may be sufficient for maintaining proficiency.","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"23 ","pages":"eAO1257"},"PeriodicalIF":0.9,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12539837/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Platypnea-orthodeoxia syndrome: echocardiography-guided percutaneous treatment. 肺动脉缺氧综合征：超声心动图引导下的经皮治疗。

IF 0.9

Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025RC1568

João de Azevedo, Fernando Hideki Sakamoto, Sofia Alves Figueiredo Faustino, César Henrique Moraes, Ítalo Menezes Ferreira, Ana Clara Tude Rodrigues, Claudio Henrique Fischer, Samira Saad Morhy, Adriana Venturini Reche, Adriano Caixeta, Marcelo Luiz Campos Vieira

{"title":"Platypnea-orthodeoxia syndrome: echocardiography-guided percutaneous treatment.","authors":"João de Azevedo, Fernando Hideki Sakamoto, Sofia Alves Figueiredo Faustino, César Henrique Moraes, Ítalo Menezes Ferreira, Ana Clara Tude Rodrigues, Claudio Henrique Fischer, Samira Saad Morhy, Adriana Venturini Reche, Adriano Caixeta, Marcelo Luiz Campos Vieira","doi":"10.31744/einstein_journal/2025RC1568","DOIUrl":"10.31744/einstein_journal/2025RC1568","url":null,"abstract":"Platypnea-orthodeoxia syndrome, first described in 1949, is a rare clinical condition characterized by positional dyspnea and oxygen desaturation in the upright position that improves when lying down. Herein, we report the case of an 86-year-old patient who experienced episodes of dyspnea on assuming an upright position, which limited her daily activities. The patient's oxygen saturation was 82% in the standing position and 91% in the supine position. During diagnostic investigation, a patent foramen ovale was identified using transesophageal echocardiography. The patient underwent percutaneous patent foramen ovale closure with an Amplatzer device, which resulted in significant improvement in her symptoms and oxygen saturation. Diagnosis of this condition requires a high index of clinical suspicion and is confirmed when the syndrome's signs and symptoms correlate with the presence of a right-to-left interatrial shunt. It is predominantly diagnosed using echocardiography with agitated saline injection.","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"23 ","pages":"eRC1568"},"PeriodicalIF":0.9,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12539809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145423166","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Percutaneous embolization of lymphatic leakage after pelvic lymphadenectomy. 盆腔淋巴结切除术后淋巴渗漏的经皮栓塞治疗。

IF 0.9

Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025RC1593

Raphael Freitas Rafael, Mariana Berquo Peleja, Guilherme Marcelino de Miranda, Rodrigo Gobbo Garcia, Eduardo Vieira Motta, Guilherme Moratti Gilberto

{"title":"Percutaneous embolization of lymphatic leakage after pelvic lymphadenectomy.","authors":"Raphael Freitas Rafael, Mariana Berquo Peleja, Guilherme Marcelino de Miranda, Rodrigo Gobbo Garcia, Eduardo Vieira Motta, Guilherme Moratti Gilberto","doi":"10.31744/einstein_journal/2025RC1593","DOIUrl":"10.31744/einstein_journal/2025RC1593","url":null,"abstract":"Background: Lymphatic leakage after pelvic lymphadenectomy is a rare complication. Furthermore, in some cases, drainage is not possible or proves insufficient to resolve this complication. Therefore, more effective and minimally invasive interventional treatments are necessary. Accordingly, this case report presents a case of transafferent nodal embolization in a 50-year-old woman who underwent videolaparoscopic total hysterectomy with pelvic lymphadenectomy. The patient developed high post-surgery vaginal flow due to a lymphatic fistula, which was identified after intranodal lymphangiography and treated successfully via transafferent nodal embolization. This case report shows the importance of considering lymphatic leakage as a possible pelvic surgery complication, particularly when accompanied by local lymphadenectomy. Moreover, the case report reveals that intranodal lymphangiography and transafferent nodal embolization are safe and highly effective methods to detect and treat this complication. This prevents the need for follow-up surgery, which may add morbidity to an otherwise uneventful postoperative period.Level of evidence: Level 5, Case Report.","PeriodicalId":47359,"journal":{"name":"Einstein-Sao Paulo","volume":"23 ","pages":"eRC1593"},"PeriodicalIF":0.9,"publicationDate":"2025-10-24","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12539827/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145558093","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Rethinking respiratory assessment: the emerging role of non-invasive Pmus estimation in real-time monitoring. 呼吸评估的再思考：无创Pmus评估在实时监测中的新作用。

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Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025CE1962

Ricardo Kenji Nawa, Germano Forti Junior, Marcelo do Amaral Beraldo

引用次数: 0

How useful is ChatGPT in answering point-of-care questions in primary care? ChatGPT在回答初级保健中的即时问题方面有多大用处？

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Einstein-Sao Paulo Pub Date : 2025-10-24 eCollection Date: 2025-01-01 DOI: 10.31744/einstein_journal/2025CE1749

Filipe Prazeres

引用次数: 0

From student organizer to leader: the role of event planning in management skill development. 从学生组织者到领导者：活动策划在管理技能发展中的作用。