Neuroradiology Journal最新文献

{"title":"Diffusion-weighted imaging and susceptibility-weighted imaging in differentiating ring-enhancing primary central nervous system lymphoma from infections.","authors":"Nutchawan Jittapiromsak, Phanuphong Sriinkua, Pornpattra Nimitpornsuko, Pakrit Jittapiromsak","doi":"10.1177/19714009251354883","DOIUrl":"10.1177/19714009251354883","url":null,"abstract":"<p><p>IntroductionDifferentiating ring-enhancing primary central nervous system lymphoma (PCNSL) from infections is critical yet challenging in clinical practice. This study aimed to evaluate the effectiveness of diffusion-weighted imaging (DWI) and susceptibility-weighted imaging (SWI) in differentiating ring-enhancing PCNSL from infections.Material and MethodsWe retrospectively reviewed 78 ring-enhancing lesions in 32 patients who underwent brain magnetic resonance imaging (MRI). Qualitative and quantitative assessments of the peripheral and central regions of ring-enhancing lesions were independently performed. The qualitative assessment involved evaluating restricted diffusion on DWI and intralesional susceptibility signal (ISS) on SWI. The quantitative assessment involved comparing the apparent diffusion coefficient average (ADC_avg) ratio and apparent diffusion coefficient minimum (ADC_min) ratio of the peripheral and central regions with the final diagnosis.ResultsThe lesions consisted of PCNSL (<i>n</i> = 21), tuberculosis (<i>n</i> = 17), and toxoplasmosis (<i>n</i> = 40). The qualitative assessment showed that diffusion was significantly more restricted at the periphery in PCNSL (<i>p</i> < .001) and that ISS positivity was significantly higher both peripherally (<i>p</i> < .001) and centrally (<i>p</i> = .001) in PCNSL than in infections. The quantitative assessment revealed that PCNSL had significantly lower ADC_avg (peripheral, <i>p</i> < .001; central, <i>p</i> = .01) and ADC_min ratios (peripheral, <i>p</i> < .001; central, <i>p</i> = .025) compared to infections. A peripheral ADC_avg ratio of <1.25 demonstrated the best diagnostic accuracy (area under the curve: 0.966, 95% confidence interval [CI]: 0.93-1.00, sensitivity: 85.7%, specificity: 89.5%, and accuracy: 88.5%) for differentiating PCNSL from infections.ConclusionRestricted diffusion on DWI, positive ISS on SWI, and ADC ratio measurements of ring-enhancing lesions demonstrate significant potential as adjunctive imaging features for distinguishing PCNSL from CNS infections.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"204-215"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12185441/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144477253","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of nuclear medicine in central nervous system evaluation.","authors":"Ghazal Shadmani, Christopher A Swingle, Chad Hunter Coffman","doi":"10.1177/19714009251345100","DOIUrl":"10.1177/19714009251345100","url":null,"abstract":"<p><p>Anatomical imaging modalities such as CT and MRI are essential for evaluating central nervous system (CNS) disorders by providing detailed visualization of structural abnormalities. Molecular and functional imaging lack detailed anatomical delineation but offer complementary insight into pathologic processes involved in a disease that is not discernable in anatomical imaging. The design of molecular and functional imaging studies for CNS disorders is driven by their underlying pathophysiology. ¹⁸F-FDG is used to evaluate neuronal metabolism, ^99mTc-based radiotracers are employed to assess brain perfusion patterns, and CSF-binding tracers are used to detect cerebrospinal fluid abnormalities. Radiopharmaceuticals that target specific receptors or pathological biomarkers enable disease-specific imaging, such as amyloid and tau PET scans in dementia, somatostatin receptor imaging with DOTATATE PET in meningiomas, and dopamine transporter imaging with DaT scan in parkinsonian syndromes. This review provides a comprehensive overview of key nuclear imaging techniques and commonly utilized radiotracers for assessing CNS pathologies. It also briefly highlights emerging trends in the role of nuclear medicine within neuroimaging, including the expanding application of theranostics for specific brain tumors.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"174-187"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12198166/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144486616","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Intradural venous engorgement of CSF-venous fistula mimics spinal dural arteriovenous fistula on MRI: A novel case report and review of literature.","authors":"Bala McRae-Posani, Ariana Thakurdyal, Marcus Konner, Craig Schreiber, David Edasery, Jared Knopman, Y Pierre Gobin, Gayle Salama","doi":"10.1177/19714009251351292","DOIUrl":"10.1177/19714009251351292","url":null,"abstract":"<p><p>Engorgement of spinal intradural veins on MRI has classically been associated with spinal dural arteriovenous fistulas (sdAVF). We report a novel case of a patient who presented with worsening cognitive impairment, whose spinal MRI demonstrated marked intradural venous engorgement in the form of serpiginous perimedullary flow voids akin to sdAVF. Further investigation led to a diagnosis of CSF-venous fistula (CVF), a sub-type of spontaneous spinal CSF leaks without an associated extradural fluid collection. This is the first reported case of CVF mimicking sdAVF on MRI. While clinical presentations of CVF and sdAVF are typically distinct, there may be overlap and/or uncertainty in atypical presentations, such as in our patient. As such, the differential for spinal intradural venous engorgement should be expanded to include spontaneous CSF leaks, including CVF.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"254-260"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12165954/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144295116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The value of black-blood MRI in cerebral venous thrombosis diagnosis: A systematic review and meta-analysis.","authors":"Ali Akhavi Milani, Saba Mehrtabar, Javad Jalili","doi":"10.1177/19714009251360558","DOIUrl":"10.1177/19714009251360558","url":null,"abstract":"<p><p>ObjectiveTo evaluate the diagnostic performance of black-blood MRI (BB-MRI) in detecting cerebral venous thrombosis (CVT).MethodsThis study was registered in PROSPERO [ID: CRD42024556451]. The PubMed/MEDLINE, Web of Science, Scopus, and Embase databases were searched for studies evaluating the performance of BB-MRI in diagnosing CVT. Studies were selected based on predefined eligibility criteria. The risk of bias was assessed using the QUADAS-2 tool. Meta-analysis was performed using a bivariate random-effects model to calculate pooled sensitivity, specificity, and area under the curve (AUC).ResultsNine studies fulfilled the eligibility criteria and were included in the review; however, two studies insufficiently reported quantitative data. Thus, seven studies involving 176 CVT patients and 217 controls, encompassing 610 thrombosed and 3279 normal cerebral venous segments, were included in the meta-analysis. The studies demonstrated a high risk of bias in the patient selection and reference standard domains. The pooled sensitivity and specificity of BB-MRI were 96% [95% CI: 92%-98%] and 96% [95% CI: 93%-98%] on a patient-based level, and 92% [95% CI: 87%-95%] and 98% [95% CI: 92%-99%] on a venous-segment-based level, respectively. The AUC was 0.98 for patient-based data and 0.96 for venous-segment-based data.ConclusionsBB-MRI demonstrates a significant potential as a diagnostic method for CVT. However, further comparative studies are needed to define its role in the diagnostic workup of patients suspected of having CVT.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"152-162"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Temporal muscle thickness on brain MRI as a surrogate marker of sarcopenia and treatment response in tremor patients undergoing MRgFUS thalamotomy.","authors":"Federico Bruno, Gaspare Saltarelli, Giovanni Di Cerbo, Antonio Innocenzi, Sandro Di Terlizzi, Patrizia Sucapane, Davide Cerone, Alessia Catalucci, Pierpaolo Palumbo, Francesco Arrigoni, Antonio Barile, Ernesto Di Cesare, Francesca Pistoia, Alessandra Splendiani","doi":"10.1177/19714009251362817","DOIUrl":"10.1177/19714009251362817","url":null,"abstract":"<p><p>BackgroundReduced Temporal Muscle Thickness (TMT) has been proposed as a marker of sarcopenia in Parkinson's Disease (PD) and Essential Tremor (ET). This study aimed to assess TMT measured on brain MRI in PD and ET patients undergoing unilateral Vim thalamotomy with MR-guided Focused Ultrasound (MRgFUS).MethodsThis retrospective single-center study (2019-2023) included patients with tremor-dominant PD or ET refractory to medical therapy. Demographic data, disease duration, and tremor severity (Fahn-Tolosa-Marin scale) were collected. Brain MRI and clinical evaluations were performed at baseline and during follow-up (1 month, 6 months, 1 year, and 2 years). TMT was manually measured on axial T1-weighted MR images. Statistical analyses evaluated differences and correlations between TMT and clinical variables.ResultsA total of 165 patients (69 PD, 96 ET) were analyzed. Disease duration was longer in ET patients (<i>p</i> < 0.001), with no significant age difference. TMT did not differ significantly between PD and ET groups (<i>p</i> = 0.08). In ET patients, TMT correlated nega-tively with age (r = -0.24, <i>p</i> = 0.03), while no correlation was found in PD patients. At 2 year follow-up, TMT negatively correlated with tremor reduction in both PD (r = -0.42, <i>p</i> = 0.03) and ET (r = -0.34, <i>p</i> = 0.05) groups.ConclusionsIn our series, no significant differences emerged between ET and PD patients regarding TMT status as a surrogate marker of sarcopenia. Lower TMT may be associated with worse tremor outcomes after MRgFUS thalamotomy and could serve as a supportive imaging biomarker in patient assessment for tremor treatment.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"247-253"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Detection of cerebral aneurysms in nonenhanced CT images of patients with subarachnoid hemorrhage using the filling defect sign.","authors":"Tristan Klintz, Justus Cordt, Naomi Larsen, Johannes Hensler, Fritz Wodarg, Olav Jansen, Sönke Peters","doi":"10.1177/19714009251348620","DOIUrl":"10.1177/19714009251348620","url":null,"abstract":"<p><p><b>Purpose:</b> Non- traumatic subarachnoid hemorrhage (SAH) constitutes a life-threatening event, which is caused in 85% by ruptured aneurysms. Identifying those aneurysms as the bleeding cause is essential for further therapy. This study explores whether relatively hypodense sparing of aneurysms in the blood-filled subarachnoid space (filling defect sign = FD) on nonenhanced CT scans (NECT) can help estimate aneurysm location and size. <b>Methods:</b> NECT of fifty patients with aneurysmal SAH, who were also examined with a catheter angiography, were retrospectively analyzed by three neuroradiologically experienced radiologists. They rated the aneurysm location and size by applying the FD. Logistic regression analysis was performed to determine if a correlation between aneurysm location, aneurysm size, Fisher score and the detectability of a FD exists. For quantitative analysis the average densities of the aneurysm were compared to that of surrounding structures. <b>Results:</b> In 75% of the cases, the aneurysm was identified correctly by using the FD. The highest detection rate was given for MCA (90%) and BA aneurysms (90%). Aneurysm location (<i>p</i> = .019), size (<i>p</i> = .020), and the Fisher score (<i>p</i> = .008) significantly influenced aneurysm detection using the FD. The aneurysm size measured in correctly identified aneurysms correlated significantly with the sizes measured in the catheter angiography (<i>p</i> < .001). A cut-off point of 51 HU could be determined to distinguish aneurysm from surrounding SAH with a specificity of 92% and a sensitivity of 86%. <b>Conclusions:</b> In three-fourths aneurysm location and size can be determined on NECT using the FD. An additional quantitative analysis can support the diagnosis with a high specificity and sensitivity.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"197-203"},"PeriodicalIF":0.8,"publicationDate":"2026-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12176784/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144318316","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Accuracy of virtual non-contrast images from dual-energy integrating detector CT and photon-counting detector CT at high iodine concentrations.","authors":"Risto Grkovski, Zsolt Kulcsar, Sebastian Winklhofer","doi":"10.1177/19714009261434498","DOIUrl":"10.1177/19714009261434498","url":null,"abstract":"<p><p>ObjectivesTo evaluate virtual non-contrast (VNC) accuracy at multiple radiation doses and iodine concentrations in a head CT phantom using dual-energy integrating-detector CT (EID-CT; TwinSpiral DECT) and photon-counting detector CT (PCD-CT).Materials and MethodsA cylindrical head-sized acrylic CT phantom with brain tissue inserts and iodine (0, 43.75, 175, and 350 mg/mL; 87.5 mg/mL was excluded due to beam-hardening artifacts) was scanned three times on each system at 100%, 80%, 75%, 65%, 50%, and 25% of the standard radiation dose to generate mixed and VNC images. Attenuations (HU) were measured in standard and corresponding VNC images; signed and absolute VNC errors were analyzed with two-way ANOVA (dose, iodine) with Tukey post hoc tests (<i>p</i> < .05), using nonparametric alternatives when assumptions were violated. Phantom HU for fat, bone, and white matter at 100% dose on EID-CT were compared with 16 patient scans to confirm realism.ResultsRadiation dose significantly affected VNC errors in both scanners, but only 25% versus 100% dose in PCD-CT was significant after Tukey (<i>p</i> = .0383); no pairwise dose differences were significant in EID-CT (<i>p</i> ≥ .07). Iodine concentration had a stronger effect. In EID-CT, 350 mg/mL differed from 0, 43.75, and 175 mg/mL (<i>p</i> < .001), with errors up to +13.7 ± 1.1 HU. In PCD-CT, 175 and 350 mg/mL differed from 0 mg/mL (<i>p</i> < .05) and from 43.75 mg/mL (<i>p</i> < .001), with a negative bias up to -10.6 ± 1.5 HU.ConclusionsDose reduction had limited impact on VNC accuracy, whereas high iodine (175-350 mg/mL) caused significant errors with opposite signed biases (EID-CT overestimation, PCD-CT underestimation). Both scanners still achieved substantial visual contrast removal.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009261434498"},"PeriodicalIF":1.2,"publicationDate":"2026-03-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC13021541/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147522398","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Standalone middle meningeal artery embolization vs. surgical evacuation in chronic subdural hematoma: A comprehensive systematic review and meta-analysis.","authors":"Ibrahim Mohammadzadeh, Bardia Hajikarimloo, Sai Sanikommu, Amirhossein Zare, Ali Mortezaei, Saba Aghajani, Ahmad Alagha, Misagh Iranpour, Mohammad Amin Habibi, Kivanc Yangi, Seyed Ali Mousavinejad, Farzan Fahim, Adam A Dmytriw, Redi Rahmani, Vratko Himic, Ricardo J Komotar, Khaled M Taghlabi, Amir H Faraji, Emade Jaman, Ahmed Abdelsalam, Ahmet Günkan, Peter Kan, Jason P Sheehan, Robert M Starke, Pascal Jabbour","doi":"10.1177/19714009261432000","DOIUrl":"10.1177/19714009261432000","url":null,"abstract":"<p><p>BackgroundChronic subdural hematoma (cSDH) remains a prevalent neurosurgical condition in elderly patients, traditionally managed via surgical evacuation when symptomatic. Middle meningeal artery embolization (MMAE) has recently emerged as a minimally invasive alternative. However, the comparative efficacy and safety of standalone MMAE versus standalone surgical evacuation remain inadequately defined.MethodsA comprehensive search of PubMed, Scopus, Embase, and Web of Science, was performed on March 20, 2025. Studies comparing standalone MMAE and standalone surgical evacuation in patients with cSDH were included. The primary outcome was recurrence; secondary outcomes included complication and mortality rates. A random-effects pairwise meta-analysis model using restricted maximum likelihood (REML) was applied to account for between-study variability.ResultsTen studies encompassing 50,138 patients were included. Recurrence was significantly lower with MMAE (RR = 0.51, 95% CI: 0.33-0.80, p = .00), with no statistically detected heterogeneity (I² = 0%), although clinical variability across studies cannot be excluded. Mortality (RR = 0.70, 95% CI: 0.44-1.12, p = .14) and complications (RR = 1.04, 95% CI: 0.67-1.64, p = .85) did not differ significantly between both groups. The GRADE assessment rated the certainty of evidence for recurrence as moderate, while the certainty for both mortality and complications were rated as very low, underscoring the need for further high-quality studies.ConclusionStandalone MMAE significantly reduces recurrence risk compared to surgical evacuation in cSDH patients, while showing no significant difference in mortality or complication rates. These findings highlight MMAE as a promising first-line treatment option, particularly for patients at high surgical risk. Prospective randomized trials are warranted to further validate these outcomes.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009261432000"},"PeriodicalIF":1.2,"publicationDate":"2026-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12979223/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"147436729","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is retirement a pain in the back? A 23-year population-based study on the impact of age and employment on spinal injections.","authors":"Shahriar Faghani, Mana Moassefi, Jennifer S McDonald, Bradley J Erickson, John C Benson","doi":"10.1177/19714009251345115","DOIUrl":"10.1177/19714009251345115","url":null,"abstract":"<p><p>PurposeSpine-related pain disorders commonly require interventions such as spinal injections, which are often image-guided and increase in demand as populations age. This study investigates the impact of lifestyle changes following retirement on the incidence of these procedures, hypothesizing that retirement significantly influences the requirement for such treatments.MethodsA review of medical records from XXX County between 2000 and 2023 was conducted, focusing on patients who received spinal injections, including epidural steroid, facet, and sacroiliac joint injections. Data were stratified by age, employment status pre- and post-procedure, and type of injection. Statistical analysis, including segmental linear regression and t-tests, was used to assess changes in incidence rates over time and across demographic subsets.ResultsOut of 134,318 patients analyzed, a total of 359,224 spinal injections were performed. There was a significant (<i>p</i>-value <.01) increase in the frequency of procedures among individuals around the age of 60, which coincides with the typical retirement age in the United States. The study also highlighted a subsequent decline in the incidence of these procedures between the ages of 70 and 74, suggesting potential adaptation to chronic conditions or the effectiveness of earlier treatments.ConclusionThe findings of this study confirm the hypothesis that retirement significantly impacts the demand for spinal injections, as evidenced by the marked increase in procedures at typical retirement ages. This underscores the importance of integrating preventive care and personalized medical guidance into healthcare strategies for individuals nearing retirement to effectively manage spine-related pain disorders and reduce the necessity for invasive treatments.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"105-110"},"PeriodicalIF":0.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12125015/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144180270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Cochlear implant imaging with accelerated flat panel computed tomography: Image quality and dosimetry comparison to conventional high-resolution multislice computed tomography.","authors":"Elie Diamandis, Sebastian Johannes Müller, Eya Khadhraoui, Stefan Klebingat, Martin Durisin, Anne Albrecht, Daniel Behme","doi":"10.1177/19714009251347856","DOIUrl":"10.1177/19714009251347856","url":null,"abstract":"<p><p>Background and PurposeCone-beam CT (CBCT) and high-resolution multislice CT (HR-MSCT) are the mainstay postoperative imaging modalities following cochlear implant (CI) surgery, with CBCT often preferred due to lower susceptibility to metallic artifacts. However, CBCT is more prone to motion artifacts due to longer acquisition times. Recent advancements in accelerated flat panel CT (Acc-FPCT) available with latest generation angiography systems addressed traditional limitations of CBCT by significantly decreasing scan time. This study evaluates the diagnostic performance and radiation dose of Acc-FPCT compared to HR-MSCT in postoperative CI evaluation.MethodsFive cadaveric whole-head specimens (ten temporal bones) were operated on by an ENT surgeon. Ten CIs were inserted via cochleostomy. Post-operatively, specimens were scanned using six Acc-FPCT protocols and HR-MSCT. Three neuroradiologists assessed the image quality of FPCT protocols in comparison to HR-MSCT using a 5-point Likert scale. Seven electrode characteristics including scalar position and discernibility of individual contacts were evaluated. Radiation dose parameters (CTDIvol and DLP) were compared among protocols.ResultsTwo high-resolution Acc-FPCT (HR-FPCT) protocols were rated superior to HR-MSCT (<i>p</i> < .01). There were no significant differences between these two protocols (<i>p</i> = .25). The remaining Acc-FPCT protocols were rated inferior to HR-MSCT (<i>p</i> < .05). Inter-rater reliability was excellent (ICC (2,k) = 0.908; CI [0.85-0.94]). DLP was significantly lower in all Acc-FPCT protocols compared to HR-MSCT.ConclusionsThe results of this study underscore the utility of Acc-FPCT protocols as a feasible alternative to HR-MSCT in postoperative CI evaluation, allowing for better visualization of electrode array while significantly reducing scan duration and radiation exposure.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"126-132"},"PeriodicalIF":0.8,"publicationDate":"2026-02-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12145409/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144250270","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}