Neuroradiology Journal最新文献_第5页

Principles of a controlled imaging environment for neonatal brain MRI: Strategies for optimal image quality and safety. 新生儿脑部磁共振成像受控成像环境的原则：优化图像质量和安全性的策略。

IF 1.3

Neuroradiology Journal Pub Date : 2025-08-01 Epub Date: 2024-11-22 DOI: 10.1177/19714009241303149

Arulnathan Ebinesh, Swarna Saxena

引用次数: 0

Overview of perianeurysmal edema following the endovascular management of cerebral aneurysms: A pooled analysis of 48 cases. 脑动脉瘤血管内治疗后动脉瘤周围水肿的概况：48例汇总分析。

IF 1.3

Neuroradiology Journal Pub Date : 2025-08-01 Epub Date: 2024-12-10 DOI: 10.1177/19714009241303130

Mohammed A Azab, Hamid Abdelma'aboud Mostafa, Oday Attalah

{"title":"Overview of perianeurysmal edema following the endovascular management of cerebral aneurysms: A pooled analysis of 48 cases.","authors":"Mohammed A Azab, Hamid Abdelma'aboud Mostafa, Oday Attalah","doi":"10.1177/19714009241303130","DOIUrl":"10.1177/19714009241303130","url":null,"abstract":"BackgroundPerianeurysmal edema occurring after endovascular treatment for cerebral aneurysms is uncommon compared to surgical clipping. The clinical aspects and the exact explanation are poorly understood.MethodsWe searched PubMed, Google Scholar, and Web of Science. We used the following keywords: \"endovascular management of cerebral aneurysms,\" \"perianeurysmal cerebral edema,\" \"perianeurysmal cerebral edema after endovascular treatment endovascular treatment,\" \"intracranial aneurysms with perianeurysmal edema,\" and \"vessel wall enhancement after endovascular therapy.\" For each case, demographic, clinicopathological, therapeutic, and follow-up data were gathered and analyzed.ResultsPerianeurysmal edema after endovascular treatment has a clear female predilection, with a male: female ratio of 12:29 (25%; 60.41%). The average time from EVT to the onset of edema ranged from 1 day to about 8 years. The aneurysm dimension ranged from 6.8 to 25 mm as the largest size reported. Most patients were asymptomatic (18 [37.5 %]), and headache was the presenting symptom in 10 patients (20.8%). Aneurysmal wall enhancement was reported in 16 (33.3 %) patients with perianeurysmal edema. About 12 patients (25%) developed post-EVT hydrocephalus. The most common coil used was the platinum type (31 [64.58%]). Most of the patients were treated expectantly with follow-up (17 [35.41 %]), while steroids were used only in 14 (29.16%) patients. Most of the patients have their edema resolved (29 [60.41%]) or stable (9 [37.5%]).ConclusionThere is growing evidence supporting the incidence of post-embolization inflammatory reactions involving the vessel wall and the surrounding parenchyma; however, the exact clinical perspectives and the predisposing factors are not fully uncovered. This analysis highlights the possible presentations and short-term outcome of patients presenting with perianeurysmal edema after endovascular management of cerebral aneurysms.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"429-437"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11632708/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142802883","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The safety and efficacy of pRESET stent retriever for treatment of thrombo-embolic stroke; a systematic review and meta-analysis. 用于治疗血栓栓塞性中风的 pRESET 支架回流器的安全性和有效性；系统回顾和荟萃分析。

IF 1.3

Neuroradiology Journal Pub Date : 2025-08-01 Epub Date: 2024-11-27 DOI: 10.1177/19714009241303083

Mohammad Amin Habibi, Muhammad Hussain Ahmadvand, Pouria Delbari, Saba Sabet, Amir Hessam Zare, Mohammad Sina Mirjani, Amir Reza Boskabadi, Zahra Aslani Kolur, Maryam Bozorgi

{"title":"The safety and efficacy of pRESET stent retriever for treatment of thrombo-embolic stroke; a systematic review and meta-analysis.","authors":"Mohammad Amin Habibi, Muhammad Hussain Ahmadvand, Pouria Delbari, Saba Sabet, Amir Hessam Zare, Mohammad Sina Mirjani, Amir Reza Boskabadi, Zahra Aslani Kolur, Maryam Bozorgi","doi":"10.1177/19714009241303083","DOIUrl":"10.1177/19714009241303083","url":null,"abstract":"BackgroundThe pRESET stent retriever is a self-expanding nitinol stent designed for mechanical thrombectomy in cases of large vessel occlusion during acute ischemic stroke. This systematic review and meta-analysis synthesize the available evidence on the safety and efficacy of the pRESET device.MethodsThis is a systematic review and meta-analysis study conducted based on the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA). The electronic databases of PubMed, Embase, WoS, and Scopus were systematically reviewed from inception to 8 July 2024.ResultsA total of eight studies involving 1163 patients were included. The pooled mortality rate was 18% with a 95% CI of [12%, 25%]. The rates of any hemorrhagic complication, parenchymal hemorrhage, and subarachnoid hemorrhage were 22% with a 95% CI of [12%, 36%], 7% with a 95% CI of [4%, 13%], and 10% with a 95% CI of [5%, 17%], respectively. The rate of favorable functional outcome (modified Rankin Scale 0-2) at 90 days was 43% with a 95% CI of [34%, 52%]. Successful recanalization rates were 60% with a 95% CI of [52%, 67%] after the first pass and 90% with a 95% CI of [83%, 95%] after the final pass. Rescue devices were used in 13% with a 95% CI of [7%, 24%] of cases.ConclusionsThe pRESET stent retriever demonstrates high recanalization rates and reasonable safety outcomes in patients undergoing mechanical thrombectomy for acute ischemic stroke due to large vessel occlusion. Further randomized trials directly comparing pRESET to other stent retrievers are warranted.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"416-428"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11603420/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142741027","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Hemodynamic changes of arteriovenous malformation and endovascular embolization. 动静脉畸形和血管内栓塞的血流动力学变化。

IF 1.3

Neuroradiology Journal Pub Date : 2025-08-01 Epub Date: 2024-11-25 DOI: 10.1177/19714009241303056

Weiming Kong, Shikai Liang, Kevin Abel Sene, Xianli Lv

{"title":"Hemodynamic changes of arteriovenous malformation and endovascular embolization.","authors":"Weiming Kong, Shikai Liang, Kevin Abel Sene, Xianli Lv","doi":"10.1177/19714009241303056","DOIUrl":"10.1177/19714009241303056","url":null,"abstract":"Objective: To analyze the hemodynamic changes caused by arteriovenous malformation (AVM) and AVM embolization through a meta-analysis of the existing literature. Method: Search for relevant studies on PubMed/Medline until November 7, 2023, and further screen the bibliographies of relevant studies to ensure comprehensive search. According to the PRISMA guidelines, manuscripts were selected to provide local hemodynamic information on AVM arterial feeders and drainage veins. Result: A total of 13 studies were included in the final analysis. The diameter of the supplying artery (y = 0.002x + 2.24, R2 = 0.99) and flow velocity (y = 0.09x + 54.55, R2 = 0.92) had a positive linear relationship with cerebral blood flow. The pressure difference through the small AVM nidus was higher than that in the large AVM, with values of (y = -12.23x + 101.39, R2 = 0.96). There was a negative linear correlation between the sessions of AVM embolization and blood flow (1 session: y = -150.7x + 564.97, R2 = 0.98 and 4 sessions: y = -118.81x + 750.07, R2 = 0.99). There was a positive linear relationship between the increase in arterial pressure, peri-AVM parenchymal perfusion, and the percentage of occlusion in the medium-sized AVMs. However, this correlation was a nonlinear relationship between elevated arterial pressure, peri-AVM parenchymal perfusion, and the percentage of large AVM occlusion. Conclusion: The hemodynamic changes of AVM (in the feeding arteries, compartments of AVM, and draining veins) follow a linear relationship. The impact of embolization on hemodynamics in medium and small AVMs follows a linear relationship. The impact of embolization of large AVMs on hemodynamics follows a nonlinear relationship.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"438-449"},"PeriodicalIF":1.3,"publicationDate":"2025-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11590089/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142717455","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Temporal muscle thickness on brain MRI as a surrogate marker of sarcopenia and treatment response in tremor patients undergoing MRgFUS thalamotomy. 脑MRI颞肌厚度作为肌少症和接受MRgFUS丘脑切除术的震颤患者治疗反应的替代标志物。

IF 0.8

Neuroradiology Journal Pub Date : 2025-07-27 DOI: 10.1177/19714009251362817

Federico Bruno, Gaspare Saltarelli, Giovanni Di Cerbo, Antonio Innocenzi, Sandro Di Terlizzi, Patrizia Sucapane, Davide Cerone, Alessia Catalucci, Pierpaolo Palumbo, Francesco Arrigoni, Antonio Barile, Ernesto Di Cesare, Francesca Pistoia, Alessandra Splendiani

{"title":"Temporal muscle thickness on brain MRI as a surrogate marker of sarcopenia and treatment response in tremor patients undergoing MRgFUS thalamotomy.","authors":"Federico Bruno, Gaspare Saltarelli, Giovanni Di Cerbo, Antonio Innocenzi, Sandro Di Terlizzi, Patrizia Sucapane, Davide Cerone, Alessia Catalucci, Pierpaolo Palumbo, Francesco Arrigoni, Antonio Barile, Ernesto Di Cesare, Francesca Pistoia, Alessandra Splendiani","doi":"10.1177/19714009251362817","DOIUrl":"10.1177/19714009251362817","url":null,"abstract":"BackgroundReduced Temporal Muscle Thickness (TMT) has been proposed as a marker of sarcopenia in Parkinson's Disease (PD) and Essential Tremor (ET). This study aimed to assess TMT measured on brain MRI in PD and ET patients undergoing unilateral Vim thalamotomy with MR-guided Focused Ultrasound (MRgFUS).MethodsThis retrospective single-center study (2019-2023) included patients with tremor-dominant PD or ET refractory to medical therapy. Demographic data, disease duration, and tremor severity (Fahn-Tolosa-Marin scale) were collected. Brain MRI and clinical evaluations were performed at baseline and during follow-up (1 month, 6 months, 1 year, and 2 years). TMT was manually measured on axial T1-weighted MR images. Statistical analyses evaluated differences and correlations between TMT and clinical variables.ResultsA total of 165 patients (69 PD, 96 ET) were analyzed. Disease duration was longer in ET patients (p < 0.001), with no significant age difference. TMT did not differ significantly between PD and ET groups (p = 0.08). In ET patients, TMT correlated nega-tively with age (r = -0.24, p = 0.03), while no correlation was found in PD patients. At 2 year follow-up, TMT negatively correlated with tremor reduction in both PD (r = -0.42, p = 0.03) and ET (r = -0.34, p = 0.05) groups.ConclusionsIn our series, no significant differences emerged between ET and PD patients regarding TMT status as a surrogate marker of sarcopenia. Lower TMT may be associated with worse tremor outcomes after MRgFUS thalamotomy and could serve as a supportive imaging biomarker in patient assessment for tremor treatment.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009251362817"},"PeriodicalIF":0.8,"publicationDate":"2025-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12303916/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144733896","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The value of black-blood MRI in cerebral venous thrombosis diagnosis: A systematic review and meta-analysis. 黑血MRI在脑静脉血栓诊断中的价值：系统回顾和荟萃分析。

IF 1.3

Neuroradiology Journal Pub Date : 2025-07-13 DOI: 10.1177/19714009251360558

Ali Akhavi Milani, Saba Mehrtabar, Javad Jalili

{"title":"The value of black-blood MRI in cerebral venous thrombosis diagnosis: A systematic review and meta-analysis.","authors":"Ali Akhavi Milani, Saba Mehrtabar, Javad Jalili","doi":"10.1177/19714009251360558","DOIUrl":"10.1177/19714009251360558","url":null,"abstract":"ObjectiveTo evaluate the diagnostic performance of black-blood MRI (BB-MRI) in detecting cerebral venous thrombosis (CVT).MethodsThis study was registered in PROSPERO [ID: CRD42024556451]. The PubMed/MEDLINE, Web of Science, Scopus, and Embase databases were searched for studies evaluating the performance of BB-MRI in diagnosing CVT. Studies were selected based on predefined eligibility criteria. The risk of bias was assessed using the QUADAS-2 tool. Meta-analysis was performed using a bivariate random-effects model to calculate pooled sensitivity, specificity, and area under the curve (AUC).ResultsNine studies fulfilled the eligibility criteria and were included in the review; however, two studies insufficiently reported quantitative data. Thus, seven studies involving 176 CVT patients and 217 controls, encompassing 610 thrombosed and 3279 normal cerebral venous segments, were included in the meta-analysis. The studies demonstrated a high risk of bias in the patient selection and reference standard domains. The pooled sensitivity and specificity of BB-MRI were 96% [95% CI: 92%-98%] and 96% [95% CI: 93%-98%] on a patient-based level, and 92% [95% CI: 87%-95%] and 98% [95% CI: 92%-99%] on a venous-segment-based level, respectively. The AUC was 0.98 for patient-based data and 0.96 for venous-segment-based data.ConclusionsBB-MRI demonstrates a significant potential as a diagnostic method for CVT. However, further comparative studies are needed to define its role in the diagnostic workup of patients suspected of having CVT.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009251360558"},"PeriodicalIF":1.3,"publicationDate":"2025-07-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12256491/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144627434","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Enhancing clot composition analysis in acute ischemic stroke with non-contrast spectral CT: A phantom-based study. 非对比光谱CT增强急性缺血性脑卒中的凝块成分分析：一项基于幻影的研究。

IF 1.3

Neuroradiology Journal Pub Date : 2025-07-03 DOI: 10.1177/19714009251356994

Juyu Chueh, Gregor Pahn, Charlie Shin, Michael Cleri, Emanuele Orrù, Neil Patel, Jonathan Pace, Timo Krings, Sebastian Flacke, Christoph Wald

{"title":"Enhancing clot composition analysis in acute ischemic stroke with non-contrast spectral CT: A phantom-based study.","authors":"Juyu Chueh, Gregor Pahn, Charlie Shin, Michael Cleri, Emanuele Orrù, Neil Patel, Jonathan Pace, Timo Krings, Sebastian Flacke, Christoph Wald","doi":"10.1177/19714009251356994","DOIUrl":"10.1177/19714009251356994","url":null,"abstract":"Acute ischemic stroke (AIS), caused by blood flow obstruction due to a clot, is a leading medical emergency, with mechanical thrombectomy (MT) being the standard of care intervention. The success of MT partly depends on the ability to effectively assess clot composition, as different clot types (e.g., erythrocyte-rich and fibrin-rich) can influence treatment outcomes. Conventional CT imaging struggles with accurately differentiating clot subtypes. Recent advancements in spectral CT imaging offer promising alternatives, but their diagnostic value remains underexplored. This study evaluates the potential of using electron density (ED) and effective atomic number (Z-effective) maps from non-contrast spectral CT (NCCT), that is, without iodine contamination for classifying clot compositions in a phantom model. Two experimental phases were conducted, with various clot analogs prepared in silicone tubes of varying diameters. Spectral CT scans were performed using a dual-layer detector system, generating conventional CT, ED, and Z-effective maps, along with virtual monoenergetic (MonoE) images. Our results revealed that ED and high-energy MonoE images (200 keV) provided superior discrimination of clot types, with larger effect sizes and higher area-under-curve (AUC) values compared to conventional CT and low-energy MonoE (40 keV) or Z-effective maps. These findings suggest that ED and high MonoE images enhance clot characterization and may improve treatment planning in AIS. However, smaller tube diameters and the inclusion of skull-equivalent material in the phantom model reduced the sensitivity and specificity of the spectral methods. This study highlights the potential of spectral CT to refine clot assessment in AIS, emphasizing the need for further clinical validation.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009251356994"},"PeriodicalIF":1.3,"publicationDate":"2025-07-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12227435/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144561494","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Factors associated with post-dural puncture headache: A single-center retrospective review. 硬脑膜穿刺后头痛的相关因素：一项单中心回顾性研究。

IF 1.3

Neuroradiology Journal Pub Date : 2025-06-30 DOI: 10.1177/19714009251345109

Rahim Ismail, Denes Szekeres, Alex Schick, Muhammad I Jalal, Tim Hoang, Aman Preet Singh, Nate French, Logan Worley, Casey Paton, Mark Manganaro, Derrek Schartz, Derek George, Alexander Kessler

{"title":"Factors associated with post-dural puncture headache: A single-center retrospective review.","authors":"Rahim Ismail, Denes Szekeres, Alex Schick, Muhammad I Jalal, Tim Hoang, Aman Preet Singh, Nate French, Logan Worley, Casey Paton, Mark Manganaro, Derrek Schartz, Derek George, Alexander Kessler","doi":"10.1177/19714009251345109","DOIUrl":"10.1177/19714009251345109","url":null,"abstract":"ObjectivePost-dural puncture headache (PDPH) is potential complication after procedures with dural puncture. This study analyzes how patient and procedural factors are related to the development of PDPH.MethodsDemographic and procedural data were extracted from the electronic medical record in patients undergoing a dural puncture procedure from 1/1/2020 to 12/31/2020. Procedural variables were extracted from procedure reports including spinal level, number of punctures, any reported complications, needle type, and gauge. Fisher-exact test, with a subgroup analysis, and multivariable logistic regression were used to analyze the association of variables with the development of a PDPH.ResultsA total of 1237 procedures with 1005 patients were identified. The mean age was 56.9 ± 16.4 years, mean BMI was 31.0 ± 7.8 kg/m2, and 534 (53.1%) identified as female. Seventy-four (7.3%) patients developed a PDPH with mean onset of 1.9 ± 1.9 days post-procedure. The likelihood of PDPH was significantly positively associated with both patient characteristics such as female sex (OR = 2.657, 95%CI [1.529,4.617], p < .001), BMI above 25 kg/m2 (OR = 2.609, 95%CI [1.177,5.786], p = .015), and history of chronic tension headaches (OR = 2.943, 95%CI [1.688,5.130], p < .0003), as well as procedural characteristics such as decreasing gauge (OR = 1.124, 95%CI [1.111,1.136], p < .0001), higher opening pressure (mean difference = -6.288 ± 2.119. p = .005).ConclusionsThis retrospective study of fluoroscopy-guided dural puncture procedures shows that the incidence of PDPH is associated with several patient and procedural characteristics.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009251345109"},"PeriodicalIF":1.3,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209233/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530407","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of a giant developmental venous anomaly and acute disseminated encephalomyelitis: A case report and magnetic resonance perfusion study. 巨大发育性静脉异常与急性播散性脑脊髓炎的关系：1例报告及磁共振灌注研究。

IF 1.3

Neuroradiology Journal Pub Date : 2025-06-30 DOI: 10.1177/19714009251356989

Louis Deprez, Emilie Lommers

{"title":"Association of a giant developmental venous anomaly and acute disseminated encephalomyelitis: A case report and magnetic resonance perfusion study.","authors":"Louis Deprez, Emilie Lommers","doi":"10.1177/19714009251356989","DOIUrl":"10.1177/19714009251356989","url":null,"abstract":"We describe the first reported association between acute disseminated encephalomyelitis (ADEM) and giant developmental venous anomaly (DVA) in the context of myelin oligodendrocyte associated glycoprotein (MOG) associated disorder (MOGAD). Patient was a young woman presenting with headache, bradypsychia and tetrapyramidal syndrome. Imaging showed disseminated tumefactive inflammatory lesions in the brain and spinal cord, with a massive right frontal lobe lesion centred around a giant DVA. Demyelinating inflammatory lesions are known to occur in a perivenular pattern, and the association between some inflammatory diseases such as multiple sclerosis (MS) and DVA has already been described. Developmental venous anomalies are variant of the normal venous drainage of the brain, responsible of a local alteration of the venular network, and micro-perfusion anomalies as well as possible increased of blood-brain barrier permeability. As such, they might be responsible for a favourable environment for pathogenic auto-antibodies penetrance in such region, potentializing the inflammatory lesion size. Perfusion imaging showed a significant increase in regional blood volume and blood transit time in the DVA and the surrounding brain tissue, which regressed in the follow-up imaging studies after the acute stage. This case illustrates the potential role of DVA in the setting of demyelinating diseases, and its consequences on the local micro-perfusion of the brain, evolving between the acute and chronic phase of the illness.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009251356989"},"PeriodicalIF":1.3,"publicationDate":"2025-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12209250/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144530406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Imaging and clinical course of metastatic pituitary neuroendocrine tumors (PitNET): A single center case series. 转移性垂体神经内分泌肿瘤（PitNET）的影像学和临床病程：单中心病例系列。

IF 1.3

Neuroradiology Journal Pub Date : 2025-06-27 DOI: 10.1177/19714009251356278

Samir A Dagher, Sahar Alizada, Heba Al Qudah, Steven G Waguespack, Komal B Shah, Rami W Eldaya

{"title":"Imaging and clinical course of metastatic pituitary neuroendocrine tumors (PitNET): A single center case series.","authors":"Samir A Dagher, Sahar Alizada, Heba Al Qudah, Steven G Waguespack, Komal B Shah, Rami W Eldaya","doi":"10.1177/19714009251356278","DOIUrl":"10.1177/19714009251356278","url":null,"abstract":"PurposeMetastatic pituitary neuroendocrine tumors (PitNET) are exceedingly rare tumors that are typically diagnosed at the time of metastasis. Given the rarity of metastatic PitNET tumors, the pattern of metastasis and imaging appearance of CNS and extra neural metastasis is under reported and poorly understood.MethodsIn this retrospective case series, we present 14 consecutive patients with pathology-confirmed metastatic PitNET tumors. We assess imaging features of primary pituitary disease at the time of diagnosis, temporal evolution of local disease, and distant metastasis on multimodality imaging. We also explore potential association of initial pathology diagnosis and time to metastasis and survival.ResultsAt the time of metastasis, nine patients had evidence of disease in the sella and three additional had evidence of disease in the cavernous sinus. The most common site of metastatic disease was the CNS (78.6%). Dural deposits were the most common brain CNS metastatic disease manifestation (81.8%). Eight patients (57.1%) demonstrated multiple metastatic disease sites, with five of them (62.5%) showing both CNS and extra CNS metastases. Osseous metastatic disease was the most common extra CNS disease site (75.0%). Median time to metastasis did not significantly differ between patients with adenoma and those with more aggressive pathologies at initial diagnosis (p value = .39). Similarly, median overall survival from metastasis detection was not significantly affected by pathology (p value = .84).ConclusionMetastatic PitNET is a rare neuroendocrine neoplasm. In the present case series, we detail temporal imaging findings of the disease at the primary site and patterns of metastasis.","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"19714009251356278"},"PeriodicalIF":1.3,"publicationDate":"2025-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12204987/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144508841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0