Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-10-25DOI: 10.1177/19714009251393176
Hideo Chihara, Yoshinori Maki, Taketo Hatano
{"title":"A rare venous drainage route from the transverse medullary vein to the inferior retrotonsillar vein on cerebral angiography.","authors":"Hideo Chihara, Yoshinori Maki, Taketo Hatano","doi":"10.1177/19714009251393176","DOIUrl":"10.1177/19714009251393176","url":null,"abstract":"<p><p>BackgroundIn vascular diseases such as arteriovenous malformations and dural arteriovenous fistulas, rare venous drainage routes can be identified angiographically.Case DescriptionA 50-year-old woman was transported to our hospital after she developed a sudden headache and unconsciousness. Computed tomography showed subarachnoid hemorrhage. A cerebral angiography disclosed an arteriovenous malformation (AVM) at the C2 level and a dural arteriovenous fistula (AVF) at C5/C6. The AVF drained through the posterior spinal vein to the inferior retrotonsillar vein. The AVM drained cranially to the anterior spinal vein flowing into the transverse medullary vein. The transverse medullary vein drained into the inferior retrotonsillar vein through a connecting vein. The connecting vein seemed very unusual.ConclusionsIn this case, a rare collateral vein connecting the transverse medullary vein and inferior retrotonsillar vein was observed.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"392-396"},"PeriodicalIF":0.8,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12553546/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145370410","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-09-05DOI: 10.1177/19714009251373063
Naoyuki Noda
{"title":"The efficacy of mechanical thrombectomy via right brachial approach for hyperacute right anterior circulation infarction.","authors":"Naoyuki Noda","doi":"10.1177/19714009251373063","DOIUrl":"10.1177/19714009251373063","url":null,"abstract":"<p><p>BackgroundMechanical thrombectomy (MT) is a well-established treatment for acute large-vessel occlusion. While the transfemoral approach (TFA) is the standard, it can be challenging in elderly patients with tortuous vasculature. The transbrachial approach (TBA) offers a shorter and more direct route but is associated with more puncture site complications. This study investigates the effectiveness and feasibility of TBA for right anterior circulation strokes.MethodsA total of 23 patients who underwent MT via TBA between September 2023 and January 2025 were retrospectively analyzed and compared with 23 patients treated via TFA from March 2021 to April 2023. Patient characteristics, procedural times, recanalization rates, and complications were evaluated.ResultsThe TBA group showed a shorter median puncture-to-guiding (PtoG) time (13 vs 16 min) and puncture-to-recanalization (PtoR) time (37 vs 52 min) compared to the TFA group. Successful recanalization (TICI ≥2b) was achieved in 95.7% of TBA cases versus 87.0% in TFA. One minor puncture site complication occurred in the TBA group. In rare instances, catheter kinking at the subclavian-CCA junction was observed. Sheathless technique was employed in most TBA cases to minimize puncture complications.ConclusionTBA is a feasible alternative for MT in right anterior circulation strokes, providing improved procedural efficiency. While associated with a higher rate of puncture complications, TBA offers a practical solution in cases where TFA or TRA may be technically challenging.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"328-331"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12413397/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145006701","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-08-25DOI: 10.1177/19714009251373067
Adam A Dmytriw, Peter B Sporns
{"title":"Toward a high-quality evidence base for pediatric stroke intervention.","authors":"Adam A Dmytriw, Peter B Sporns","doi":"10.1177/19714009251373067","DOIUrl":"10.1177/19714009251373067","url":null,"abstract":"","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"397"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12378101/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973865","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-10-14DOI: 10.1177/19714009251387296
Davi Barbosa Pereira, Rafaela Correia Maciel, Wei Jun Lee, Vivian Castilho, Rodrigo Dos Reis Schevz, Maria Clara de Sousa Morais, Gabriela Quaresma Sardella, Samir Said Abdul Rahim, Catherine Dos Reis Schevz, Ismael Augusto Silva Lombardi
{"title":"Comparative benefits of particle embolization versus liquid agents in preoperative management of meningiomas: A Systematic Review and Meta-analysis.","authors":"Davi Barbosa Pereira, Rafaela Correia Maciel, Wei Jun Lee, Vivian Castilho, Rodrigo Dos Reis Schevz, Maria Clara de Sousa Morais, Gabriela Quaresma Sardella, Samir Said Abdul Rahim, Catherine Dos Reis Schevz, Ismael Augusto Silva Lombardi","doi":"10.1177/19714009251387296","DOIUrl":"10.1177/19714009251387296","url":null,"abstract":"<p><p>IntroductionPreoperative embolization reduces intraoperative blood loss (IBL) in meningioma treatment, but the optimal embolic material remains uncertain. This systematic review and meta-analysis compares the effectiveness and safety of particle versus liquid embolic agents in the preoperative embolization of meningiomas.MethodsPubMed, Cochrane, Embase, and Scopus were searched for studies comparing particles and liquid embolic agents in patients undergoing preoperative embolization of meningiomas. Primary outcomes included the degree of devascularization, IBL, ischemic events, and overall complications. The risk of bias was assessed using the ROBINS-I. Statistical analyses were conducted using R.ResultsThe analysis included four studies, covering a total of 1827 patients. Particles were associated with a significantly lower incidence of operative complications (OR = 0.35; 95% CI 0.20-0.62; <i>p</i> < 0.001; I<sup>2</sup> = 0.0%). The other outcomes did not differ between groups. Regarding IBL, no significant difference was observed between particulate and liquid embolic agents (MD = -65.01 mL; 95% CI -237.01-107.00; <i>p</i> = 0.46; I<sup>2</sup> = 77.8%).ConclusionOur systematic review and meta-analysis indicate no significant differences between particulate and embolic agents; however, particulate agents were associated with a lower incidence of overall complications, suggesting a potential advantage in perioperative safety.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":"39 3","pages":"280-289"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12521160/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"148018268","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-08-03DOI: 10.1177/19714009251365745
Kamand Khalaj, Elham Tavakkol, Luis Nunez, Jordan Jafarnia, Antonio Dono, Octavio Arevalo, Andres Rodriguez, Jay-Jiguang Zhu, Yoshua Esquenazi, Roy Riascos, David Timaran-Montenegro
{"title":"IDH wild-type glioblastoma: Predictive value of standard-of-care (SOC) MRI for establishing MGMT promoter methylation status.","authors":"Kamand Khalaj, Elham Tavakkol, Luis Nunez, Jordan Jafarnia, Antonio Dono, Octavio Arevalo, Andres Rodriguez, Jay-Jiguang Zhu, Yoshua Esquenazi, Roy Riascos, David Timaran-Montenegro","doi":"10.1177/19714009251365745","DOIUrl":"10.1177/19714009251365745","url":null,"abstract":"<p><p>PurposeOxygen 6-methylguanine-DNA methyltransferase (MGMT) promoter methylation is associated with better chemotherapy response and prognosis in glioblastoma patients. This study evaluates the prognostic value of routine MRI findings at initial diagnosis to determine MGMT promoter methylation status.MethodsA retrospective study was performed on 85 patients with histologically confirmed IDH wild-type glioblastoma. Patients were divided into two groups based on MGMT promoter status: methylated (33 [38.8%]) and unmethylated (52 [61.1%]). MRI findings were assessed using the Visually Accessible Rembrandt Imaging lexicon, and variables were analyzed using univariate analysis (X<sup>2</sup>/Fisher's test) and logistic regression for independent predictors of MGMT promoter methylation.ResultsA thick enhancing tumoral margin (≥3 mm) was present in 67.3% of MGMT unmethylated glioblastomas and 32.7% of MGMT promoter methylated glioblastomas (<i>p</i> = .05). Tumoral cortical extension was observed in 68.7% of unmethylated cases versus 31.3% in methylated cases (<i>p</i> = .01). Non-enhancing tumors were predominantly MGMT methylated (83.3%). In multivariate analysis, tumoral cortical involvement and non-enhancing tumors were independent predictors of MGMT promoter methylation. In survival analysis, higher progression-free survival rates were identified in patients with MGMT promoter methylation (<i>p</i> = .05) and in patients without cortical tumoral extension (<i>p</i> = .05).ConclusionOur study suggests that while the predictive power of the assessed parameters is modest, thick enhancing tumoral margins and cortical tumor extension were more frequently identified in MGMT unmethylated glioblastomas. Conversely, 83.3% of non-enhancing tumors showed MGMT promoter methylation. Furthermore, MGMT promoter methylation and cortical extension were associated with progression-free survival.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"299-308"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12321826/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144776493","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-10-21DOI: 10.1177/19714009251389579
Ali Mortezaei, Nadir Al-Saidi, Kiana Yahyaei, Ahmed Abdelsalam, Luis Guada Delgado, Joshua Hanna, Adam A Dmytriw, Redi Rahmani, Adib A Abla, Robert M Starke
{"title":"Middle meningeal artery embolization versus standard of care for chronic subdural hematoma: Meta-analysis of randomized controlled trials.","authors":"Ali Mortezaei, Nadir Al-Saidi, Kiana Yahyaei, Ahmed Abdelsalam, Luis Guada Delgado, Joshua Hanna, Adam A Dmytriw, Redi Rahmani, Adib A Abla, Robert M Starke","doi":"10.1177/19714009251389579","DOIUrl":"10.1177/19714009251389579","url":null,"abstract":"<p><p>BackgroundThe safety and efficacy of the middle meningeal artery embolization (MMAE) in patients with non-acute or chronic subdural hematoma (cSDH) has significant reporting within recent literature, however, mainly in the form of observational data.MethodsWe conducted a systematic review and meta-analysis including all available randomized clinical trials (RCTs) that compared MMAE in addition to standard of care (SOC) versus SOC alone for cSDH. The primary outcome was the rate of recurrence and reoperation. Secondary outcomes included serious adverse events (SAEs), mortality rate, independent ambulation (modified Rankin Scale (mRS) score 0<b>-</b>3), and changes in hematoma characteristics at 90 days. The fixed-effect or random-effects model was used based on the significancy of the heterogenicity (I<sup>2</sup> > 50%, <i>P</i> < .1).ResultsFindings showed significant superiority of MMAE over SOC in 90-day recurrence (RR = 0.55, 95% CI = 0.36<b>-</b>0.83, <i>P</i> = .0047, I<sup>2</sup> = 43.3%), reoperation within 180 days (RR = 0.38, 95% CI = 0.26-0.56, <i>P</i> < .001, I<sup>2</sup> = 0.0%), ambulatory functional outcome (RR = 1.034, 95% CI = 1.0-1.07, <i>P</i> = .0296, I<sup>2</sup> = 53.9%), SAE at any time (RR = 0.59, 95% CI = 0.38-0.94, <i>P</i> = .025, , I<sup>2</sup> = 0.0%), and 90-day any-cause mortality (RR = 0.29, 95% CI = 0.14-0.6, <i>P</i> = .0008, I<sup>2</sup> = 0.0%). Successful embolization and 30-day embolization-related complications occurred in 99.2% (95% CI = 94.54%<b>-</b>100%) and 1.18% (95% CI = 0.39%<b>-</b>2.31%) of patients, respectively. Additionally, subgroup analyses on major and pilot RCTs, comparison of embolic agents, and MMAE adjuvant to surgery versus surgery alone confirmed these findings.ConclusionMMAE appears to be safe and effective in the management of cSDH with low recurrence and SAE rate.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"290-298"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12540358/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145349193","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Usefulness of amide proton transfer images in the diagnosis of malignant glioma comparison of APT images and 11C-methionine-positron emission tomography.","authors":"Masami Shirota, Masayuki Nitta, Taiichi Saitou, Syunsuke Tsuduki, Ayako Yoshida, Yoshihiro Muragaki, Takakazu Kawamata","doi":"10.1177/19714009251345107","DOIUrl":"10.1177/19714009251345107","url":null,"abstract":"<p><p>IntroductionAmide proton transfer (APT) imaging is one of the imaging methods in Magnetic Resonance Imaging (MRI). It is a molecular imaging technique that visualizes contrast based on the concentration or exchange rate of amide groups of amino acids, which increases in tumors. Methionine-positron emission tomography (MET-PET), on the other hand, has been found to be useful in the imaging diagnosis of glioma because of its clear contrast in the accumulation of tumor cells. In this study, we compared APT and MET-PET on the basis of pathological diagnostic results and backwardly examined whether APT is useful for the imaging diagnosis of glioma.MethodForty-six patients with malignant glioma (World Health Organization 2016 (WHO2016) Grade: GII/III/IV) and suspected pseudoprogression who underwent APT and MET-PET were included in the study. For APT, APT signals were measured in the tumor region of interest, and for MET-PET, 370 MBq was administered to measure the tumor-to-normal tissue ratio (TNR).ResultIn the correlation verification, the actual APT and TNR were correlated with 2.22 ± 1.01 and 2.58 ± 1.5, respectively (r = 0.6, <i>p</i> < 0.001). The accuracy of the differentiation between GII/III/IV (32 patients) and suspected pseudoprogression (14 patients) by actual APT measurements was verified with a sensitivity of 91% and specificity of 100% at a cutoff value of 1.81. In the validation of malignancy diagnosis, the measured APT value of GII (6 cases) was 2.18 ± 0.43 and the TNR was 3.53 ± 2.12, the measured APT value of GIII (11 cases) was 2.67 ± 0.69 and TNR was 2.81 ± 0.72, and the measured APT value of GIV (15 cases) was 2.99 ± 0.61 and the TNR was 3.44 ± 1.28. The APT measured value and TNR differed significantly in malignancy diagnoses, with higher grades having higher values. Genetic diagnosis validation revealed that the oligodendroglioma group (GII/III: 10 cases) had an APT of 2.37 ± 0.66 and a TNR of 3.52 ± 1.41, while the astrocytoma group (GII/III: 7 cases) had an APT of 2.67 ± 0.45 and a TNR of 2.41 ± 0.87.ConclusionAPT may be comparable to MET-PET in differentiating suspected pseudoprogression and in diagnosing malignancy. Patients with an actual APT of 1.81 or higher should be considered for a treatment plan, whereas follow-up may be an option for those with an APT of 1.81. Although the TNR tends to be higher in the oligodendroglioma group (GII/III), APT, which is not affected by the blood-brain barrier, has less variability in actual measurements and is useful for the imaging diagnosis of glioma.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"271-279"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12460284/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145139042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-10-08DOI: 10.1177/19714009251385226
Sai Viswan Thiagarajah, Edward Cornish, Amit Kapoor, Jeremy Telford, Thomas Langstroth, Kenneth Koo
{"title":"GIRFT guidance reduces cauda equina syndrome (CES) related admissions without negatively impacting diagnosis.","authors":"Sai Viswan Thiagarajah, Edward Cornish, Amit Kapoor, Jeremy Telford, Thomas Langstroth, Kenneth Koo","doi":"10.1177/19714009251385226","DOIUrl":"10.1177/19714009251385226","url":null,"abstract":"<p><p><b>Background:</b> Cauda equina syndrome (CES) is a rare but serious neurosurgical emergency. Back pain and sciatica are common presentations to A&E. Get It Right First Time (GIRFT) published guidance in February 2023 regarding the red flag symptoms and symptom duration requiring emergency MRI. This framework has been utilised by the orthopaedic service within our hospital. The aim of this study was to assess whether implementing GIRFT guidance could reduce CES related admissions without impacting the diagnostic yield for identifying this emergency.<b>Methods:</b> Retrospective review of all emergency MRI scans to exclude CES during two 6-month periods. GIRFT guidance was published in February 2023. Period 1 (01/08/2022-31/01/2023) was prior to GIRFT guidance and period 2 (01/08/2024-31/01/2025) was more than 1 year after GIRFT guidance. Statistical analysis was undertaken using Chisquared and Mann-Whitney testing. <b>Results:</b> There were 175 emergency MRI scans to exclude CES during period 1 versus 159 during period 2. After implementation of GIRFT guidance, there was a significant reduction in the percentage of patients requiring admission (42.77% vs 56.57%, <i>p</i> = 0.016) and an increase in the percentage of patients scanned on the day of presentation (61.64% vs 52.57%, <i>p</i> = 0.119). There was no change in the diagnostic yield of scans for identifying CES (4.57% vs 4.4%, <i>p</i> = 1). <b>Conclusion:</b> Our results show that utilisation of the GIRFT guidance reduced CES related admissions without negatively impacting diagnostic yield. These findings highlight the value of implementing GIRFT guidelines in neurosurgical and orthopaedic departments across the country.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"353-359"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12507797/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145253280","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Neuroradiology JournalPub Date : 2026-06-01Epub Date: 2025-08-26DOI: 10.1177/19714009251373065
Federico Sabuzi, Nicola Cavasin, Mariafrancesca Trulli, Simone Di Candia, Michelangelo Digregorio, Francesco Garaci, Valerio Da Ros
{"title":"Widening the treatment of shallow intracranial aneurysms with intrasaccular flow disruption: The flat WEB experience.","authors":"Federico Sabuzi, Nicola Cavasin, Mariafrancesca Trulli, Simone Di Candia, Michelangelo Digregorio, Francesco Garaci, Valerio Da Ros","doi":"10.1177/19714009251373065","DOIUrl":"10.1177/19714009251373065","url":null,"abstract":"<p><p>The Woven EndoBridge (WEB) device's effectiveness and safety have been thoroughly assessed in several clinical practice trials. The availability of new WEB sizes expanded the indications for the endovascular treatment of intracranial wide-necked aneurysms. We retrospectively analysed data from all patients with intracranial aneurysms treated with a 6 × 2 or 7 × 2 WEB in two institutions; endovascular embolization was performed both in unruptured and ruptured aneurysms. Seven patients with 7 wide-necked aneurysms were included; one aneurysm was ruptured. All aneurysms involved the anterior circulation. Technical success of embolization performed with flat WEB devices was accomplished and no intraprocedural complications occurred. At 3 months follow-up, adequate occlusion was obtained for six treated aneurysms. With the availability of new WEB sizes, broad-based aneurysms with unfavourable height and aspect ratio are suitable for embolization using intrasaccular flow disruption in our preliminary experience; larger series are needed to confirm their long-term efficacy.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"373-377"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12380741/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144973951","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Outcome of intraoperative heparinization during stent-assisted coiling for unruptured aneurysms.","authors":"Takashi Fujii, Shuta Maehara, Yoshimasa Fukui, Kousei Maruyama, Kosuke Takigawa, Noriaki Tashiro, Hidetoshi Matsukawa, Yoshiya Hashiguchi, Masanobu Yasumoto, Masahiro Yasaka, Hiroshi Aikawa, Yoshinori Go, Kiyoshi Kazekawa","doi":"10.1177/19714009251377750","DOIUrl":"10.1177/19714009251377750","url":null,"abstract":"<p><p>In this study, we aimed to compare the treatment outcomes of patients with unruptured aneurysms treated using stent-assisted coil embolization with and without systemic heparinization to examine the intraoperative systemic heparinization efficacy. We included 106 consecutive patients enrolled at Fukuoka Neurosurgical Hospital, Japan, between November 2021 and March 2023. The patients were divided into two groups: the systemic heparinization and nonsystemic heparinization groups. Head magnetic resonance imaging (MRI) performed on postoperative day 1 showed that the number of ischemic foci <2 mm was higher in the nonsystemic heparinization group than in the systemic heparinization group, although the difference was not statistically significant (2 [0-6] vs 1 [0-3], <i>P</i> = .0583). No significant between-group difference was observed concerning the incidence of ischemic and hemorrhagic complications. There was no significant between-group difference regarding the modified Rankin scale (mRS) score; however, the systemic heparinization group had a higher proportion of patients with poor outcomes than did the nonsystemic heparinization group, with one (2.4%) patient with an mRS score of 5 and one (2.4%) patient with an mRS score of 6. In conclusion, intraoperative systemic heparinization during stent-assisted coil embolization of unruptured cerebral aneurysms may suppress diffusion-weighted imaging high-signal spots on head MRI performed on postoperative day 1. Moreover, systemic heparinization may worsen the outcomes of hemorrhagic complications.</p>","PeriodicalId":47358,"journal":{"name":"Neuroradiology Journal","volume":" ","pages":"332-339"},"PeriodicalIF":1.2,"publicationDate":"2026-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12432005/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145041942","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}