Oral and Maxillofacial Surgery-Heidelberg最新文献

{"title":"Primary surgery of subcondylar mandibular fracture using patient-specific implant: comment.","authors":"Amnuay Kleebayoon, Viroj Wiwanitkit","doi":"10.1007/s10006-025-01363-1","DOIUrl":"https://doi.org/10.1007/s10006-025-01363-1","url":null,"abstract":"<p><p>This is a comment on published article on primary surgery of subcondylar mandibular fracture using patient-specific implant.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"67"},"PeriodicalIF":1.7,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671509","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Age-related and positional changes in facial angles: insights from an Asian cohort.","authors":"Hyun Su Lee, Dong Hwan Kwon, Minheon Kim, Jae Woo Lee, Dong-Joon Park, Young-Ha Lee, Eun Jung Lee","doi":"10.1007/s10006-025-01368-w","DOIUrl":"https://doi.org/10.1007/s10006-025-01368-w","url":null,"abstract":"<p><strong>Aim: </strong>Since aging leads to changes in facial angles, the effect of age on impressions of facial appearance involves factors such as face shape, eye color, nose size and placement, and mouth size and placement, as well as skin morphological and tonal characteristics, including wrinkles, spots, and sagging. Identifying the extent of change in facial angles can aid surgeons in interpreting facial landmarks before nasal surgery. Hence, this study evaluated changes in facial angles at different positions in a cohort of older Asian patients.</p><p><strong>Methods: </strong>This study enrolled 47 patients admitted for nasal surgeries, including 33 men (70.2%) and 14 women (29.8%). The average age was 48.15 ± 18.7. Nasolabial, nasofrontal, nasomental, and nasofacial angles were measured in the sitting, supine, and neck extension positions. Patients were divided into two groups: younger (≤ 60 years, n = 28) and older (> 60 years, n = 19) to evaluate the effect of age on facial angles.</p><p><strong>Results: </strong>The supine-extension nasofacial (p = 0.031) and nasomental (p = 0.023) angles decreased with age. Concurrently, nasolabial angles increased with age in the sitting-supine position (p = 0.012) and sitting-extension positions (p = 0.019). Additionally, the analysis of variance and regression model demonstrated a decrease of 0.019°/year in nasofacial angle between the supine and neck extension positions, whereas the nasomental angle between these positions declined by 0.032°/year. In contrast, between the sitting and supine postures and the sitting and extension positions, the absolute difference in nasolabial angles increased (0.140°/year and 0.128°/year).</p><p><strong>Conclusion: </strong>This preliminary study showed that facial angle characteristics changed more between different postures in the older age group; thus, clinicians should exercise caution when performing aesthetic nasal procedures in older patients.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"69"},"PeriodicalIF":1.7,"publicationDate":"2025-03-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143671501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Primary surgery of subcondylar mandibular fracture using patient-specific implant. Comment by Amnuay Kleebayoon & Viroj Wiwanitkit: author's reply.","authors":"Mikko Saloniemi, Salli Malla, Lehtinen Valtteri, Snäll Johanna","doi":"10.1007/s10006-025-01365-z","DOIUrl":"https://doi.org/10.1007/s10006-025-01365-z","url":null,"abstract":"","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"66"},"PeriodicalIF":1.7,"publicationDate":"2025-03-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143659168","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Fabrication of porous collagen-stem cells-dexamethasone scaffold as a novel approach for regeneration of mandibular bone defect.","authors":"Nader Tanideh, Mobina Sarikhani, Mina Emami, Masih Alipanah, Yasaman Mohammadi, Mohammad Mokhtarzadegan, Akram Jamshidzadeh, Shahrokh Zare, Sajad Daneshi, Ali Feiz, Cambyz Irajie, Aida Iraji","doi":"10.1007/s10006-025-01353-3","DOIUrl":"https://doi.org/10.1007/s10006-025-01353-3","url":null,"abstract":"<p><strong>Background: </strong>Bone defects, particularly in the mandible, pose significant clinical challenges due to the limited regenerative capacity. Effective bone tissue engineering requires biomaterials that promote both osteogenesis and angiogenesis. This study developed an optimized collagen-nano hydroxyapatite scaffold loaded with dexamethasone and stem cells to enhance bone regeneration.</p><p><strong>Methods: </strong>The scaffold was fabricated using the freeze-dryer method. Characterization was performed using Fourier Transform Infrared Spectroscopy (FTIR), energy-dispersive X-ray (EDX) analysis, and scanning electron microscopy (SEM). Wharton's jelly-derived mesenchymal stem cells (WJ-MSCs) were incorporated into the scaffold, and in vitro and in vivo assessments were conducted.</p><p><strong>Results: </strong>FTIR and EDX analyses confirmed the successful incorporation of nano-hydroxyapatite and dexamethasone. SEM revealed an interconnected porous structure with an average pore size of 28.55 µm. The scaffold loaded with WJ-MSCs significantly enhanced osteocyte and osteoblast populations, leading to improved mandibular bone formation. Histopathological evaluations demonstrated superior osteogenesis and angiogenesis.</p><p><strong>Conclusion: </strong>The developed porous nanohybrid scaffold shows potential as a promising biomaterial for bone tissue engineering applications.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"65"},"PeriodicalIF":1.7,"publicationDate":"2025-03-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143639672","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Radioanatomical characteristics of zygoma for planning of quad zygoma implants: a cross sectional study.","authors":"Shashti Balaji, Karthik Kattur Premkumar, Deepak Abraham Pandyan, Satheesh Chandran, Deenadayalan Narasimman, Balamurugan Rajendran, George Samyo Stephenson","doi":"10.1007/s10006-025-01361-3","DOIUrl":"https://doi.org/10.1007/s10006-025-01361-3","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate the radioanatomical measurements of the zygoma as a guide for treatment planning of quad zygomatic implant placement.</p><p><strong>Methods: </strong>This cross sectional study was carried on 17 patients of 34 zygomatic regions reported with atrophic maxilla for placement of zygomatic implants. The zygomatic implants were placed virtually in a quad approach using \"Real Guide\" version 3.0\" and, the following parameters were assessed at 20 points in antero- superior, antero-inferior, postero-superior and postero-inferior regions. The thickness of zygomatic bone, Installation angle of zygomatic implants, Length of the installed zygomatic implants and Distance between the zygomatic implants on each side were measured using Cone Beam Computed Tomography (CBCT) on a virtual planning software \"Materialise Mimics\" version 15.</p><p><strong>Results: </strong>The mesial implant can be emerged in antero-superior region and the distal implant can be emerged in antero-inferior region on the right side zygoma since the maximum thickness of zygomatic bone was seen in D2, A1, A3 and D4 directions. Similarly in the left side of zygoma, the mesial implant can emerge in postero-superior region and distal implant can be emerge in postero-inferior region since the maximum thickness was seen in D2 and A3 directions (P > 0.05). The installation angle for mesial implant in right and left side was 45⁰ and the distal implant angle for right and left side was 45⁰ and 46⁰ (P < 0.05). The mesial zygomatic implant length for right and left side was 55.88 mm and 56.18 mm while, the distal zygomatic implant length for right and left side was 44.56 mm and 45.59 mm (P > 0.05). The distance between the two zygomatic implants in right and left side was 5.06 mm and 4.54 mm (P > 0.05).</p><p><strong>Conclusion: </strong>Virtual planning for placement of implants in quad zygoma approach would be a feasible requirement as it eases out the surgeon's practice and prevents the possibilities of causing intrusion complications intraoperatively. Hence, quad zygoma implants remains a promising viable option for patients presenting with severe atrophic maxilla.</p><p><strong>Clinical trial number: </strong>Not Applicable.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"64"},"PeriodicalIF":1.7,"publicationDate":"2025-03-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143606629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"An unusual case of multiple primary tumours involving the long bone and oral cavity.","authors":"Karthick Sekar, Anand Ramanathan, Rafiq Khalid, Kein Seong Mun, Valliammai Valliappan, Siti Mazlipah Ismail","doi":"10.1007/s10006-025-01356-0","DOIUrl":"https://doi.org/10.1007/s10006-025-01356-0","url":null,"abstract":"<p><strong>Purpose of review: </strong>Multiple primary tumours (MPTs) are a rare clinical entity, and the co-occurrence of synchronous and metachronous MPTs in a single patient is even more exceptional. In the context of Erdheim-Chester Disease (ECD), an already uncommon disorder, the presentation of this disease in the oral cavity is notably rare. Furthermore, the simultaneous presence of ECD in the oral cavity and a Giant Cell Tumour (GCT) in a long bone has not been previously reported in medical literature.</p><p><strong>Recent findings: </strong>This case report presents the first documented instance of such a unique clinical scenario. The marked histological disparities between GCT and ECD further underscore the enigmatic nature of this case. The intricate interplay of genetic, environmental, and pathophysiological factors that led to the simultaneous development of two distinct neoplasms in the same patient is yet to be fully elucidated. This case not only challenges our understanding of the etiology of these conditions but also emphasizes the importance of a multidisciplinary approach to the evaluation and management of such complex cases. The confluence of rare entities, the diagnostic complexities they introduce, and the imperative need for tailored treatment strategies exemplify the intricate landscape of oncological care. This case serves as a compelling reminder of the many unknown facets of disease etiology and the significance of collaborative medical efforts in offering the best possible care for patients confronting exceptionally rare clinical presentations.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"62"},"PeriodicalIF":1.7,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The lip split: a retrospective outcomes study of central and lateral lip split access for head and neck reconstructive surgery.","authors":"Peter Gearing, Maxim Devine, Siyuan Pang, Felix Sim, Anand Ramakrishnan","doi":"10.1007/s10006-025-01355-1","DOIUrl":"10.1007/s10006-025-01355-1","url":null,"abstract":"<p><strong>Purpose: </strong>Surgical resection of oral cancers requires meticulous planning to achieve clear margins and minimize potential morbidity. This study aimed to compare postoperative surgical and functional outcomes following central and lateral lip-split approaches used for resection and reconstruction of oral tumours.</p><p><strong>Methods: </strong>A retrospective review of 79 cases involving lip-split procedures for head and neck cancers was conducted. Data were collected from a prospectively recorded database (December 2015 to December 2022). Statistical analyses compared patient demographics, intraoperative characteristics, and postoperative outcomes between central and lateral lip-split cohorts.</p><p><strong>Results: </strong>Lateral lip splits were associated with higher rates of postoperative complications (p = 0.008), including return to theatre (p = 0.015), and functional issues including asymmetric smile (p = 0.009). No significant differences were observed in readmission rates, length of stay, or time to oral diet commencement (p > 0.05).</p><p><strong>Conclusions: </strong>Lip-split procedures remain valuable for resection and reconstruction of oral and oropharyngeal tumours. Lateral lip splits are associated with poorer outcomes when compared to central approaches. Appropriate selection of lip splitting approaches should consider tumour location, resection margins, patient comorbidities and preferences, and surgical preferences.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"63"},"PeriodicalIF":1.7,"publicationDate":"2025-03-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11885361/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143568479","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Is oral and maxillofacial surgery lagging behind other specialties on X?","authors":"Boyu Ma, Jamie Rose, Edwin M Rojas, Jaime Castro-Núñez","doi":"10.1007/s10006-025-01359-x","DOIUrl":"10.1007/s10006-025-01359-x","url":null,"abstract":"<p><strong>Purpose: </strong>X, formerly known as Twitter, is a popular social media platform that facilitates oral and maxillofacial surgeons to disseminate a wide array of information to a global audience. The purpose of this study is to identify the top influencers in oral and maxillofacial surgery on X, characterize who they are, and relate their social media influence to academic influence.</p><p><strong>Methods: </strong>We utilized the \"BuzzSumo\" Application Programming Interface to identify the most followed accounts for the topic search \"oral and maxillofacial surgery.\" A secondary calculator from the Mention API was used to assign a numerical score of \"influence\" based on their algorithm. The top 100 accounts associated with the highest engagement scores were characterized by name, status as an oral and maxillofacial surgeon/organization, location, and academic h-index.</p><p><strong>Results: </strong>We found that 52/100 (52%) of users/organizations were oral and maxillofacial surgeons/residents. There was no significant correlation between the h-index and the X engagement score, R² = 0.8316 (P = 0.088). In comparison, other specialties have a higher percentage of practitioners using X and have found a correlation between h-index and X engagement score.</p><p><strong>Conclusion: </strong>Our results indicate there is a demonstrated need for the creation of more educational content from high-ranking academic sources.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"61"},"PeriodicalIF":1.7,"publicationDate":"2025-03-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11882611/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143558355","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparing academic productivity and Instagram presence in oral and maxillofacial surgery training programs.","authors":"Jamie Rose, Boyu Ma, Edwin M Rojas, Jaime Castro-Núñez","doi":"10.1007/s10006-025-01354-2","DOIUrl":"10.1007/s10006-025-01354-2","url":null,"abstract":"&lt;p&gt;&lt;strong&gt;Background: &lt;/strong&gt;Social media has become an increasingly important tool in how surgeons collaborate with one another, disseminate educational information, and communicate with patients.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Purpose: &lt;/strong&gt;The purpose of this study was to assess the relationship between academic productivity and social media (Instagram) presence amongst oral and maxillofacial surgery programs.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Study design, setting, sample: &lt;/strong&gt;A cross-sectional study was used to identify oral and maxillofacial surgery programs and their respective residency Instagram accounts. Information regarding number of followers, posts, and likes were recorded for each program. Academic productivity metrics for each faculty including H-index, number of publications, and number of citations were recorded.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Predictor/exposure/independent variable: &lt;/strong&gt;The independent variable was the type of residency program: certificate, dual-degree, or combined track.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Main outcome variable(s): &lt;/strong&gt;The main outcome variable was the academic influence quantified by h-index, citations, and publications of the programs and their social media influence quantified by number of followers/posts.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Covariates: &lt;/strong&gt;Instagram posts were categorized into departmental posts, educational, social, professional and miscellaneous. Engagement was further quantified by the number of likes.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Analyses: &lt;/strong&gt;Descriptive statistics, one-way ANOVA, Tukey's Multiple Comparisons tests, ROUT's outlier test (Q = 0.1%), and linear regression plots with a P value &lt; 0.05.&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Results: &lt;/strong&gt;Instagram accounts were identified for 65 (73%) of the 89 programs. There was a statistically significant moderately positive correlation between the number of followers for a program's Instagram account compared with the number of publications (r = 0.5110, P  &lt; 0.001). There was a statistically significant weakly positive correlation between the number of followers for a program's Instagram account compared with average faculty h-index(r = 0.4982, P  &lt; 0.001), and number of citations (r = 0.4300, P  &lt; 0.001). There was a statistically significant weakly positive correlation between the number of posts for a program's Instagram account compared with average faculty h-index (r = 0.3438, P &lt; 0.001), number of publications (r = 0.3580, P = 0.001), and number of citations (r = 0.3973, P  &lt; 0.001). Across all programs combined, educational posts garnered more likes compared to miscellaneous (P = 0.0129), social (P = 0.0018), departmental (P = 0.0005), and professional posts (P &lt; 0.0001).&lt;/p&gt;&lt;p&gt;&lt;strong&gt;Conclusion/relevance: &lt;/strong&gt;There was a moderately positive correlation between average faculty H-index and number of followers for an oral and maxillofacial surgery program's Instagram account. There was a weak positive correlation between other measures of academic productivity and social media presence. Educational content ","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"60"},"PeriodicalIF":1.7,"publicationDate":"2025-03-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11880069/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143544009","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Evaluation of two stable internal fixation techniques in mandibular ramus sagittal osteotomy: a three-dimensional finite element study.","authors":"Kaline de Moura Silva, Leonardo Mendes Ribeiro Machado, Milena Gomes Melo Leite, Pedro Yoshito Noritomi, Giorge Pessoa de Jesus, Andrezza Lauria de Moura","doi":"10.1007/s10006-025-01357-z","DOIUrl":"https://doi.org/10.1007/s10006-025-01357-z","url":null,"abstract":"<p><strong>Purpose: </strong>To evaluate and compare, using finite elements three-dimensional (3D) analysis, two techniques of stable internal fixation in 2 patterns of sagittal split ramus osteotomy (SSRO) and the repercussions of occlusal load distribution in the postoperative period.</p><p><strong>Methods: </strong>A 3D finite element model of a hemimandible was created. The models were divided into 2 split patterns of SSRO advanced 5 mm forward, a split pattern (1) following the Epker osteotomy design and another split pattern (2) following Posnick osteotomy design, simulated by CAD (Computer Aided Engineering) Rhinoceros 3D^®. Two internal fixation techniques were simulated by HyperMesh: A- one titanium miniplate of the Arnett system (1 mm) for orthognathic surgery fixed with four monocortical screws; B- one titanium plate fixed with four monocortical screws and one bicortical screw. Resistance, stress and displacement were analyzed applying a 200 N vertical load to the occlusal surface region of the mandibular first molar and a 100 N to the incisal surface of the mandibular central incisor.</p><p><strong>Results: </strong>The results were presented through the von Mises stress analysis. A difference in the displacement of the models fixed with only one miniplate and four monocortical screws was observed. The models with split pattern (2) presented smaller displacements when compared to the split pattern (1). For metallic components, the split pattern (2) exhibits lower strain values, although it has no significant difference.</p><p><strong>Conclusion: </strong>The fixation technique B proved to be more rigid and lower stress values both in the bone and in the plate, as well as lower deformation and displacements were shown in comparison to fixation technique A for all mandibular movements and forces.</p>","PeriodicalId":47251,"journal":{"name":"Oral and Maxillofacial Surgery-Heidelberg","volume":"29 1","pages":"59"},"PeriodicalIF":1.7,"publicationDate":"2025-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143517015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}