Polish Journal of Radiology最新文献

{"title":"Imaging spectrum of rhino-orbital-cerebral mucormycosis secondary to COVID-19 infection: a reporting checklist.","authors":"Yogeshwari Anay Deshmukh,&nbsp;Sanjay Vaid,&nbsp;Aparna Chandorkar,&nbsp;Ashish Atre,&nbsp;Sunil Patil","doi":"10.5114/pjr.2022.117647","DOIUrl":"https://doi.org/10.5114/pjr.2022.117647","url":null,"abstract":"<p><p>In recent times, India has been in the midst of a notifiable epidemic of mucormycosis (a rare angio-invasive fungal infection), within the ongoing global coronavirus disease 2019 (COVID-19) pandemic. Epidemiological studies have reported the estimated prevalence of mucormycosis to be around 70 times higher in India as compared to the global data, even in the pre-COVID era. However, in the last 3 months, our city witnessed an unprecedented surge in cases of post-COVID-19-associated rhino-orbital-cerebral (ROC) mucormycosis. This pictorial review aims to illustrate the entire imaging spectrum of mucormycosis in the head-neck-face region. Along with the usual sites (nose, paranasal sinuses, orbits), this disease also involves the skull base, palate, temporal bone, and deep neck spaces. Many cases also demonstrated morbid and, at times, fatal intracranial and neurovascular complications. This review also aims to provide a structured reporting template that will prove useful to the radiologists interpreting imaging studies of ROC mucormycosis.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e333-e347"},"PeriodicalIF":1.2,"publicationDate":"2022-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/7b/96/PJR-87-47358.PMC9288200.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40548341","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Local recurrence of renal cell carcinoma after partial nephrectomy: applicability of the apparent diffusion coefficient of MRI as an imaging marker - a multicentre study.","authors":"Yulian Mytsyk,&nbsp;Andriy Borzhiyevskyy,&nbsp;Ihor Dutka,&nbsp;Alexander Shulyak,&nbsp;Paweł Kowal,&nbsp;Dmytro Vorobets,&nbsp;Michał Skrzypczyk,&nbsp;Oleksandr Borzhiyevs'kyy,&nbsp;Andrzej Górecki,&nbsp;Viktoria Matskevych","doi":"10.5114/pjr.2022.117593","DOIUrl":"https://doi.org/10.5114/pjr.2022.117593","url":null,"abstract":"<p><strong>Purpose: </strong>The goal of the study was an assessment of the diagnostic performance of diffusion-weighted images (DWI) and apparent diffusion coefficient (ADC) of magnetic resonance imaging (MRI) in distinguishing local recurrence (LR) of renal cell carcinoma (RCC) from benign conditions after partial nephrectomy.</p><p><strong>Material and methods: </strong>Thirty-nine patients after partial nephrectomy for solid RCC were enrolled in the study. Patients were followed up using MRI, which included DWI sequence (<i>b</i> = 800 s/mm²). All patients with MRI features of LR were included in the main group (<i>n</i> = 14) and patients without such features - into the group of comparison (<i>n</i> = 25). Apparent diffusion coefficient (ADC) values of suspicious lesions were recorded. In all patients with signs of locally recurrent RCC, surgical treatment was performed followed by pathologic analysis.</p><p><strong>Results: </strong>The mean ADC values of recurrent RCC demonstrated significantly higher numbers compared to benign fibrous tissues and were 1.64 ± 0.15 × 10^-3 mm²/s vs. 1.02 ± 0.26 × 10^-3 mm²/s (<i>p</i> < 0.001). The mean ADC values of RCCs' LR and benign post-op changes in renal scar substantially differed from mean ADC values of healthy kidneys' parenchyma; the latter was 2.58 ± 0.05 × 10^-3 mm²/s (<i>p</i> < 0.001). In ROC analysis, the use of ADC with a threshold value of 1.28 × 10^-3 mm²/s allowed us to differentiate local recurrence of RCC from benign postoperative changes with 100% sensitivity, 80% specificity, and accuracy: AUC = 0.980 (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>The apparent diffusion coefficient of DWI of MRI can be used as a potential imaging marker for the diagnosis of local recurrence of RCC.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e325-e332"},"PeriodicalIF":1.2,"publicationDate":"2022-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/e0/dc/PJR-87-47353.PMC9288198.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40548340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Interrater reliability and agreement of the liver imaging reporting and data system (LI-RADS) v2018 for the evaluation of hepatic lesions.","authors":"Ahmed S Abdelrahman,&nbsp;Sherihan S Madkour,&nbsp;Mena E Y Ekladious","doi":"10.5114/pjr.2022.117590","DOIUrl":"https://doi.org/10.5114/pjr.2022.117590","url":null,"abstract":"<p><strong>Purpose: </strong>The liver imaging reporting and data system (LI-RADS) is a structured reporting system that categorizes hepatic observations according to major imaging features and lesion size, with an optional ancillary features contribution. This study aimed to evaluate inter-reader agreement of dynamic magnetic resonance imaging (MRI) using LI-RADS v2018 lexicon.</p><p><strong>Material and methods: </strong>Forty-nine patients with 69 hepatic observations were included in our study. The major and ancillary features of each hepatic observation were evaluated by 2 radiologists using LI-RADS v2018, and the interreader agreement was allocated.</p><p><strong>Results: </strong>The inter-reader agreement of major LI-RADS features was substantial; κ of non-rim arterial hyperenhancement, non-peripheral washout appearance, and enhancing capsule was 0.796, 0.799, and 0.772 (<i>p</i> < 0.001), respectively. The agreement of the final LI-RADS category was substantial with κ = 0.651 (<i>p</i> < 0.001), and weighted κ = 0.786 (<i>p</i> < 0.001). The inter-reader agreement of the ancillary features was substantial to almost perfect (k range from 0.718 to 1; <i>p</i> < 0.001). An almost perfect correlation was noted for the hepatic lesion size measurement with ICC = 0.977 (<i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>The major and ancillary features of the LI-RADS v2018, as well as the final category and lesions size, have substantial to almost perfect inter-reader agreement.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e316-e324"},"PeriodicalIF":1.2,"publicationDate":"2022-06-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/28/81/PJR-87-47352.PMC9288199.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40563780","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Volumetric analysis of mandibular lesions with SPECT/CT: a pilot clinical study of maximum standardized uptake value.","authors":"Yoshiyuki Minami,&nbsp;Ruri Ogawa,&nbsp;Ichiro Ogura","doi":"10.5114/pjr.2022.117569","DOIUrl":"https://doi.org/10.5114/pjr.2022.117569","url":null,"abstract":"<p><strong>Purpose: </strong>This study was designed to investigate mandibular lesions using volumetric analysis with bone single-photon emission computed tomography/computed tomography (SPECT/CT).</p><p><strong>Material and methods: </strong>Eight patients with mandibular lesions underwent SPECT/CT scan acquisition 4 hours after injection of Tc-99m hydroxymethylene diphosphonate (HMDP). Regarding volumetric analysis, maximum standar-dized uptake value (SUV) was obtained using software and a workstation (Q.Volumetrix MI and GEniE-Xeleris 4 DR, respectively). The localization and size of the volume of interest (VOI) can be drawn over the lesion, mesial, distal, and opposite side as normal using the CT, SPECT, and SPECT/CT transaxials, coronals, and sagittals as the anatomical reference. Q.Volumetrix MI can analyse SUV of lesions by organ segmentation using optional pan and zoom imaging. Then, the dosimetry software provided multiple quantitative data for a given VOI. Statistical analyses for the maximum SUV were performed by Mann-Whitney <i>U</i> test. A <i>p</i>-value lower than 0.05 was considered as statistically significant.</p><p><strong>Results: </strong>Maximum SUVs for medication-related osteonecrosis of the jaw (<i>n</i> = 4, 25.4 ± 4.9), chronic osteomyelitis (<i>n</i> = 3, 14.6 ± 3.1), and squamous cell carcinoma (<i>n</i> = 1, 31.7) were significantly higher than those of the opposite side as normal mandible (3.8 ± 0.7, 4.6 ± 1.8, and 7.4, respectively; <i>p</i> = 0.000).</p><p><strong>Conclusions: </strong>Volumetric analysis with SPECT/CT could be useful for the evaluation of mandibular lesions, such as detecting and surgical planning.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e311-e315"},"PeriodicalIF":1.2,"publicationDate":"2022-06-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/9b/35/PJR-87-47339.PMC9288195.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40563778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Lymphadenopathy in the era of COVID-19 vaccination - an oncological dilemma in diagnostic imaging.","authors":"Jakub Samkowski,&nbsp;Katarzyna Sklinda,&nbsp;Jerzy Michał Walecki","doi":"10.5114/pjr.2022.117560","DOIUrl":"https://doi.org/10.5114/pjr.2022.117560","url":null,"abstract":"<p><p>Initial clinical experience with COVID-19 vaccination suggests that approved COVID-19 mRNA vaccines induce a strong immune response and thus cause a significantly higher incidence of axillary lymphadenopathy compared with other vaccines. It can therefore be expected to complicate the diagnosis of patients with overt or suspected mali-gnancy, in whom it may be indistinguishable from malignant node involvement. There is a need for guidelines on the appropriate management of unilateral axillary lymph node enlargement. This article studies the available reports on vaccine-associated lymphadenopathy. It also presents a basic strategy for the assessment of axillary lymphadenopathy based on preliminary recommendations and an algorithm. According to these recommendations, screening should be scheduled before or at least 4-6 weeks after the last dose of the vaccine. This will allow reactive adenopathy to resolve and avoid unnecessary and costly axillary lymph node biopsy. Clear and effective communication between patients, radiologists, referring physician teams, and the general public is the way forward in the management of adenopathy following COVID-19 vaccination. Herein we present 5 cases of lymph node enlargement after mRNA vaccine administration from different authors. Their initial radiological diagnosis raised concerns that they might be metastases. Therefore, radiologists need to include COVID-19 vaccination in the differential diagnosis of patients with unilateral axillary adenopathy. Short-term follow-up of unilateral axillary adenopathy with recent COVID-19 vaccination is an appropriate recommendation.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e304-e310"},"PeriodicalIF":1.2,"publicationDate":"2022-06-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a2/46/PJR-87-47337.PMC9288197.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40563779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparison of high-pitch prospective electrocardiogram-gated pulmonary CT angiography with standard CT pulmonary angiography on dual-source CT for detection of subsegmental pulmonary embolism in patients suspected of acute pulmonary embolism.","authors":"Rohini Thakur,&nbsp;Manphool Singhal,&nbsp;Ashutosh Nath Aggrawal,&nbsp;Ujjwal Gorsi,&nbsp;Navneet Sharma,&nbsp;Ashish Bhalla,&nbsp;Niranjan Khandelwal","doi":"10.5114/pjr.2022.117065","DOIUrl":"https://doi.org/10.5114/pjr.2022.117065","url":null,"abstract":"<p><strong>Purpose: </strong>Objective of this study was to compare high-pitch prospective electrocardiogram (ECG)-gated computed tomography (CT) pulmonary angiography (HP-PECG-gated CTPA) with standard-pitch non-ECG-gated CT pulmonary angiography (SP-NECG-gated CTPA) on 128-slice dual-source CT (DSCT) for the detection of subsegmental pulmonary embolism (SSPE) in patients suspected of acute pulmonary embolism (APE) with radiation and contrastoptimized protocols. Cardiac-related motion artefacts, lung image quality, and quantitative parameter (pulmonary arterial enhancement, radiation exposure, and contrast) volumes were also compared.</p><p><strong>Material and methods: </strong>This prospective study enrolled 87 patients clinically suspected of APE and randomly distributed to either group by software. Two radiologists blinded to each other interpreted the images for assessment of SSPE, image quality, and quantitative parameters.</p><p><strong>Results: </strong>SSPE was diagnosed in 15/44 (34.09%) patients in HP-PECG-gated CTPA, in comparison to 8/43 (18.60%) patients in SP-NECG-gated CTPA. Cardiac motion-related artefacts (blurring of bronchovascular structures and double-line artefacts) were statistically significantly less, with <i>p</i>-value < 0.05. Lung image quality was also better, with <i>p</i>-value < 0.001. Effective radiation dose and contrast volume in HP-PECG-gated CTPA were (2.54 ± 0.80 mSv, 45.05 ± 6 ml) versus SP-NECG-gated CTPA (3.17 ± 1.20 mSv, 74.19 ± 7.63 ml) with <i>p</i>-values of 0.007 and 0.001, respectively.</p><p><strong>Conclusions: </strong>Radiation and contrast volume-optimized HP-PECG-gated CTPA provides reduced cardiac motion related artefacts of pulmonary arteries, which allows enhanced detection of SSPE. It also provides better image quality of lung and parenchyma with lower radiation exposure and less contrast volume.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e296-e303"},"PeriodicalIF":1.2,"publicationDate":"2022-05-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/ca/55/PJR-87-47234.PMC9215302.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40467704","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Diagnostic performance and inter-observer variability of CO-RADS in the triage of patients with suspected COVID-19 infection: initial experience in Zagazig University Hospital.","authors":"Dena Abd El Aziz El Sammak,&nbsp;Hala M Allam,&nbsp;Rabab M Abdelhay","doi":"10.5114/pjr.2022.117052","DOIUrl":"https://doi.org/10.5114/pjr.2022.117052","url":null,"abstract":"<p><strong>Purpose: </strong>In many healthcare settings in developing nations, multislice computed tomography (MSCT) imaging may be the only available diagnostic modality for patients with suspected COVID-19 infection, due to a shortage of laboratory kits. This study aimed to evaluate the diagnostic performance and interobserver variability of CO-RADS (COVID-19 Reporting and Data System) in the triage of patients with suspected COVID-19 infection in Zagazig University Hospital.</p><p><strong>Material and methods: </strong>This study included 2500 patients with suspected COVID-19 infection, mean age 60.61 years ± 13.89. 61.4% were male. Unstable patients requiring urgent invasive ventilation, acute coronary syndrome patients, pregnant females, and patients with RT-PCR results available prior to MSCT were excluded from this study. RT-PCR was performed in all patients included in the study.</p><p><strong>Results: </strong>Fever and dry cough were the most common clinical symptoms, detected in 80.16% and 52.00%, respectively. The most common comorbidities were cardiovascular diseases, followed by chronic lung disease and diabetes, found in 27.36%, 22.80%, and 18.00%, respectively. Of the 1500 RT-PCR-positive patients, 40% had CO-RADS score 5, while 3.4% had CO-RADS score 1. Of the 1000 RT-PCR-negative patients, 36% had CO-RADS score 2 and 1% were scored as CO-RADS 5. There was excellent agreement in the studied patients as the weighted κ value was 0.846, which was more pronounced at CO-RADS 5 (24.40%). The sensitivity of CO-RADS was higher in the 2^nd scenario (83.27% vs. 55.27%) while the specificity was higher in the 1^st scenario (95% vs. 65%).</p><p><strong>Conclusion: </strong>The CO-RADS scoring system is a sensitive and specific method that can help in the diagnosis of COVID-19 during the peak of the COVID-19 pandemic. CO-RADS is a triage test in resource-constrained environments, assisting in the optimization of RT-PCR tests, isolation beds, and intensive care units.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e286-e295"},"PeriodicalIF":1.2,"publicationDate":"2022-05-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/1b/43/PJR-87-47232.PMC9215304.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40561681","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"The role of diffusion-weighted imaging and dynamic contrast-enhanced magnetic resonance imaging for the diagnosis of diabetic foot osteomyelitis: a preliminary report.","authors":"Shashank Raj,&nbsp;Mahesh Prakash,&nbsp;Ashu Rastogi,&nbsp;Anindita Sinha,&nbsp;Manavjit Singh Sandhu","doi":"10.5114/pjr.2022.116637","DOIUrl":"https://doi.org/10.5114/pjr.2022.116637","url":null,"abstract":"<p><strong>Purpose: </strong>To assess the role of dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) and diffusionweighted imaging (DWI) in diagnosing diabetic foot osteomyelitis (DFO).</p><p><strong>Material and methods: </strong>Twenty-five participants with suspected osteomyelitis were included, who underwent MRI including DCE-MRI and DWI sequences. It was subsequently followed by bone biopsy and microbiological analysis (gold standard). The participants were divided into 2 groups based on biopsy results: DFO-positive or DFO-negative. The semi-quantitative DCE-MRI parameters (SI₀, SI_max, SI_rel, wash-in rate [WIR], and type of curve) and apparent diffusion coefficient (ADC) values were subsequently compared between the 2 groups.</p><p><strong>Results: </strong>Out of the 25 cases, 19 were DFO-positive and 6 were DFO-negative on bone biopsy. The SI₀, SI_max, and WIR were significantly higher in DFO-positive cases (<i>p</i>-value 0.050, 0.023, and 0.004, respectively). No difference was seen in SI_rel. 100% negative cases revealed type-I curve, and 94% of positive cases showed type-II curve. SI₀ > 143.4 revealed a sensitivity of 94.7% and specificity of 83.3%. SI_max had a sensitivity of 89.5% but lower specificity of 67.7% at a cut-off value of 408.35. The most significant difference was seen with WIR; <i>p</i>-value ~0.004. At the cut-off value of > 1.280, it had a specificity and sensitivity of 100% and 76%, respectively. Also, ADC values below 1.57 × 10^-3 had a sensitivity of 88.2% and specificity of 80% for diagnosing DFO.</p><p><strong>Conclusions: </strong>DWI and DCE-MRI provide non-invasive sequences, which can help to increase the overall specificity and sensitivity of conventional MRI for the diagnosis of osteomyelitis, differentiating it from acute Charcot's arthropathy.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e274-e280"},"PeriodicalIF":1.2,"publicationDate":"2022-05-23","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/b9/8b/PJR-87-47129.PMC9215298.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40561680","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Feature-tracking cardiac magnetic resonance method: a valuable marker of replacement fibrosis in hypertrophic cardiomyopathy.","authors":"Nahid Rezaeian,&nbsp;Leila Hosseini,&nbsp;Negar Omidi,&nbsp;Mahya Khaki,&nbsp;Homa Najafi,&nbsp;Kianoosh Kasani,&nbsp;Mostafa Mousavizadeh,&nbsp;Yasaman Khalili,&nbsp;Mohammad Mehdi Hemmati Komasi,&nbsp;Yaser Toloueitabar,&nbsp;Sanaz Asadian","doi":"10.5114/pjr.2022.116548","DOIUrl":"https://doi.org/10.5114/pjr.2022.116548","url":null,"abstract":"<p><strong>Purpose: </strong>Left ventricular (LV) replacement fibrosis is a marker of adverse cardiac events in hypertrophic cardiomyopathy (HCM). We aimed to assess the efficacy of the feature-tracking cardiac magnetic resonance (FT-CMR) in the detection of LV replacement fibrosis.</p><p><strong>Material and methods: </strong>Fifty-one patients with HCM (51% female, mean age = 21 ± 5.2 years) and significant myocardial hypertrophy, who underwent CMR between February 2018 and December 2019 were enrolled. Functional and 3D FT-CMR parameters were measured. LV global longitudinal strain, global radial strain (GRS), and global circumferential strain (GCS) were recorded. The percentage of enhanced myocardial mass was calculated. Univariate and multivariate regression analyses were performed to determine the predictors of fibrosis. A <i>p</i>-value of less than 0.05 was considered significant.</p><p><strong>Results: </strong>The mean enhanced mass percentage was 15.2 ± 10.53%. Among LV volumetric parameters, end-systolic and end-diastolic volume indices predicted fibrosis (fitness [F] = 8.11 and <i>p</i> = 0.006 vs. <i>F</i> = 6.6 and <i>p</i> = 0.012, correspondingly). The univariate linear regression demonstrated that GCS and GRS predicted total enhanced mass (%) (<i>F</i> = 12.29 and <i>p</i> = 0.001 vs. <i>F</i> = 7.92 and <i>p</i> = 0.007, respectively). After the inclusion of all volumetric and deformation parameters, the multivariate analysis identified the model of a combination of LV end-diastolic volume index (LV EDVI) and LV GCS as a robust predictor of the fibrosis percentage (<i>F</i> = 8.86 and <i>p</i> = 0.005).</p><p><strong>Conclusions: </strong>Non-contrast CMR parameters including LV GCS and LV EDVI are valuable markers of replacement fibrosis in HCM patients with notable myocardial hypertrophy.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e263-e270"},"PeriodicalIF":1.2,"publicationDate":"2022-05-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/54/ff/PJR-87-47102.PMC9215299.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40561678","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

{"title":"Comparative evaluation of severity of COVID-19 pneumonia on computed tomography of the chest in vaccinated and non-vaccinated individuals: an observational study.","authors":"Manik Mahajan,&nbsp;Vikrant Gupta,&nbsp;Mohd Ilyas,&nbsp;Kulbhushan Gupta,&nbsp;Parveen Singh","doi":"10.5114/pjr.2022.116192","DOIUrl":"https://doi.org/10.5114/pjr.2022.116192","url":null,"abstract":"<p><strong>Purpose: </strong>Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel virus causing an infectious disease, coronavirus disease 2019 (COVID-19). Computed tomography (CT) of the chest plays a significant role in the diagnosis and prognosis of COVID-19 using computed tomography severity scoring (CT-SS). Numerous vaccines are being made available in the world to lessen the effect of the COVID-19 pandemic. The purpose of the current study is to compare the severity of COVID-19 pneumonia using CT-SS in COVID-19-positive vaccinated (Covishield/Oxford-AstraZeneca) and non-vaccinated individuals and to compare the final outcome wherever possible.</p><p><strong>Material and methods: </strong>This observational study was carried out from March 2021 to April 2021. Forty vaccinated and 40 non-vaccinated RT-PCR-positive COVID-19 patients who underwent CT chest during the 4-12^th day of illness formed the material of the study. Semi-quantitative scoring was used, and CT-SS was calculated based on the extent of lobar involvement in all the patients. CT-SS was then compared between the vaccinated and non-vaccinated groups and the results analysed.</p><p><strong>Results: </strong>CT scans were performed in 80 patients (40 patients each in the vaccinated and non-vaccinated groups). The majority of patients in the vaccinated group had mild (42.5%) and moderate (37.5%) CT-SS while the majority of patients in the non-vaccinated group had moderate (52.5%) and severe (27.5%) CT-SS score on chest CT. Also, no mortality was observed in the vaccinated group, with 2 deaths in the non-vaccinated group.</p><p><strong>Conclusions: </strong>Covishield vaccine administration reduces the severity of COVID-19 pneumonia as compared to the nonvaccinated group, with a marked reduction in mortality.</p>","PeriodicalId":47128,"journal":{"name":"Polish Journal of Radiology","volume":" ","pages":"e257-e262"},"PeriodicalIF":1.2,"publicationDate":"2022-05-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/a2/cb/PJR-87-47012.PMC9215301.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"40467703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}