JOURNAL OF MEDICAL INVESTIGATION最新文献_第6页

Kinematics of an intervertebral disc with type 1 Modic change: mechanical and non-mechanical causes. 1型模态改变椎间盘的运动学：机械和非机械原因。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.385

Yuji Yamada, Masatoshi Morimoto, Toru Maeda, Syogo Tomiyama, Naoyuki Yoshida, Masahiro Kashima, Koichi Sairyo

{"title":"Kinematics of an intervertebral disc with type 1 Modic change: mechanical and non-mechanical causes.","authors":"Yuji Yamada, Masatoshi Morimoto, Toru Maeda, Syogo Tomiyama, Naoyuki Yoshida, Masahiro Kashima, Koichi Sairyo","doi":"10.2152/jmi.72.385","DOIUrl":"https://doi.org/10.2152/jmi.72.385","url":null,"abstract":"Purpose: Type 1 Modic change (MC) is associated with chronic low back pain and attributed to segmental instability. However, the relationship between type 1 MC and segmental instability is unclear. This study sought to clarify the role of mechanical abnormalities in type 1 MC.Method: Review of magnetic resonance images obtained for 727 patients over a 1-year period at our institution revealed 161 cases of type 1 MC. In 86 of these, the following indicators of mechanical abnormality could be evaluated on dynamic radiographs:segmental scoliosis (>5°), forward slippage (>1%), and posterior disc opening in flexion. Patients with one or more of these abnormalities were allocated to a mechanical group (n=62, 70%) and those with no abnormality to a non-mechanical group (n=26, 30%). The Pfirrmann grade of disc degeneration at the affected level was compared between the groups.Results: Segmental scoliosis, slippage, and posterior opening was observed in 34, 21 and 37 cases, respectively. Severe disc degeneration (grade IV or V) was present in 43 cases (69%) in the mechanical group and in 12 cases (46%) in the non-mechanical group;the difference was statistically significant (p=0.04).Conclusion: We propose that there are mechanical and non-mechanical variants of type 1 MC. J. Med. Invest. 72 : 385-389, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"385-389"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439666","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Increase in the amyotrophic lateral sclerosis age of onset:Analysis of cases originating in 2011-2020. 肌萎缩性侧索硬化症发病年龄增加：2011-2020年发病病例分析

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.286

Kenta Hanada, Shotaro Haji, Koji Fukushima, Hiroki Yamazaki, Yusuke Osaki, Naoko Takamatsu, Koji Fujita, Yushin Izumi

{"title":"Increase in the amyotrophic lateral sclerosis age of onset:Analysis of cases originating in 2011-2020.","authors":"Kenta Hanada, Shotaro Haji, Koji Fukushima, Hiroki Yamazaki, Yusuke Osaki, Naoko Takamatsu, Koji Fujita, Yushin Izumi","doi":"10.2152/jmi.72.286","DOIUrl":"https://doi.org/10.2152/jmi.72.286","url":null,"abstract":"The onset age of amyotrophic lateral sclerosis (ALS) has been increasing, but recent trends remain unclear. This study examined changes in ALS onset age over the past decade. We analyzed 233 ALS patients diagnosed from 2011 to 2020 at Tokushima University Hospital. The Jonckheere-Terpstra test assessed the trend in onset age. We compared onset age between 2011-2015 (Group A) and 2016-2020 (Group B) using the Mann-Whitney U test. We also analyzed the annual proportion of patients with onset age ≥80 using Spearman's rank correlation. In Tokushima Prefecture, we evaluated annual increase rates of individuals aged ≥80 and ALS patients with onset age ≥80, using 2011 as baseline. Regression slopes were compared using a t test. Onset age showed a significant positive trend (p=0.04), and Group B had older onset age than Group A (p=0.048). The proportion of patients with onset age ≥80 increased significantly (ρ=0.69, p=0.03). No significant difference was found between regression slopes for the general elderly population and ALS patients with onset age ≥80 (p=0.49). These findings suggest that the onset age of ALS at Tokushima University Hospital has increased over the past decade. J. Med. Invest. 72 : 286-289, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"286-289"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Diagnostic Ability of Texture Analysis in MR Imaging for Neurogenic Tumors. 磁共振成像纹理分析对神经源性肿瘤的诊断能力。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.367

Tomoki Matsushita, Takayoshi Shinya, Toshihiko Nishisho, Koichi Sairyo, Yoshimi Bando, Hisanori Uehara, Masafumi Harada

{"title":"The Diagnostic Ability of Texture Analysis in MR Imaging for Neurogenic Tumors.","authors":"Tomoki Matsushita, Takayoshi Shinya, Toshihiko Nishisho, Koichi Sairyo, Yoshimi Bando, Hisanori Uehara, Masafumi Harada","doi":"10.2152/jmi.72.367","DOIUrl":"https://doi.org/10.2152/jmi.72.367","url":null,"abstract":"Objectives: Malignant peripheral nerve sheath tumors (MPNSTs) are rare neoplasms requiring differentiation from benign neurogenic tumors on diagnostic imaging. We evaluated the diagnostic utility of texture analysis (TA) in distinguishing seven pathologically confirmed MPNSTs from eight schwannomas using magnetic resonance imaging (MRI), including T1- (T1WI) and T2-weighted imaging (T2WI), and apparent diffusion coefficient (ADC) maps. TA's performance was compared with that of conventional approaches using ADC values alone.Methods: Tumors were segmented, and 90 texture features were extracted using LIFEx software. Significantly different features (p < 0.05) were identified using the Mann-Whitney U test and evaluated through receiver operating characteristic (ROC) analysis. ADC maps were used to measure the minimum, mean, and maximum ADC values, followed by ROC analysis.Results: Two T2WI-based texture features (neighborhood grey-tone difference matrix Contrast and grey-level size zone matrix Grey Level Variance) demonstrated the highest diagnostic performance (area under the curve = 0.911 [95% confidence interval (CI):0.755-1.000]), comparable to the minimum and mean ADC values (area under the curve = 0.898 [95% CI:0.691-1.000]).Conclusions: TA may help differentiate MPNSTs from schwannomas. T2WI-based TA offers a viable alternative when ADC maps are limited by magnetic susceptibility artifacts. J. Med. Invest. 72 : 367-374, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"367-374"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439814","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Recent advances in the management of allergic rhinitis. 过敏性鼻炎治疗的最新进展。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.14

Yoshiaki Kitamura, Seiichiro Kamimura, Tatsuya Fujii, Keisuke Ishitani, Naoki Kimoto, Hitoshi Shono, Ryo Kanamura, Eiji Kondo, Takahiro Azuma, Go Sato, Hiroyuki Mizuguchi

{"title":"Recent advances in the management of allergic rhinitis.","authors":"Yoshiaki Kitamura, Seiichiro Kamimura, Tatsuya Fujii, Keisuke Ishitani, Naoki Kimoto, Hitoshi Shono, Ryo Kanamura, Eiji Kondo, Takahiro Azuma, Go Sato, Hiroyuki Mizuguchi","doi":"10.2152/jmi.72.14","DOIUrl":"https://doi.org/10.2152/jmi.72.14","url":null,"abstract":"Allergic rhinitis (AR) is a type I allergic disease characterized by sneezing, watery rhinorrhea, and nasal obstruction. An epidemiological survey found that approximately 50% of Japanese individuals have AR.Histamine is a major chemical mediator that induces AR symptoms through its binding to histamine H1 receptor(H1R). We demonstrated that antihistamines have a blocking effect on histamine signaling of H1R, and the suppressive effect on histamine-induced up-regulation of transcriptional activation, and the suppressive effect on basal transcription of H1R in the absence of histamine which may be part of the inverse agonist action of antihistamine. Sublingual immunotherapy (SLIT) with a standardized Japanese cedar (JC) pollen significantly improved nasal symptoms and AR-related sleep disturbance in patients with JC pollinosis. Dual SLIT with JC pollen and house dust mites (HDM) suppressed both JC pollen-induced seasonal and HDM-induced perennial nasal symptoms in bisensitized patients with AR. Dual SLIT was more effective in suppressing nasal obstruction at the peak JC pollen period than mono SLIT with JC pollen. Posterior nasal neurectomy (PNN) improved nasal symptoms and medication scores in patients with severe perennial AR. Herein, we describe recent advances in the management of AR. J. Med. Invest. 72 : 14-20, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"14-20"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040459","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Two-stage cranial reconstruction with a custom-made titanium plate using a preliminary bipedicled scalp flap : A case report. 订制钛板及初步双蒂头皮瓣两期颅骨重建1例报告。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.185

Mitsutoshi Okuda, Yoshiro Abe, Keiichi Goishi, Kenta Ikushima, Kenji Akome, Hiroshi Harada, Ichiro Hashimoto

{"title":"Two-stage cranial reconstruction with a custom-made titanium plate using a preliminary bipedicled scalp flap : A case report.","authors":"Mitsutoshi Okuda, Yoshiro Abe, Keiichi Goishi, Kenta Ikushima, Kenji Akome, Hiroshi Harada, Ichiro Hashimoto","doi":"10.2152/jmi.72.185","DOIUrl":"https://doi.org/10.2152/jmi.72.185","url":null,"abstract":"A 75-year-old woman presented with scalp and cranial defects caused by implant exposure, infection,and cranial necrosis following multiple craniotomies. To reduce the risk of complications after cranioplasty, weplanned a two-stage cranial reconstruction. A wide bipedicled scalp flap with a long longitudinal axis above the cranium covered the scalp defect after debridement, and skin grafting was performed on the periosteum after flap harvesting during the first surgery. A custom-made titanium plate was implanted under the bipedicled flap during the second cranioplasty 4 months after the initial surgery. The patient had no complications during the two surgeries, and her clinical course was uneventful for 6 months after the last surgery. Although a two-stage approach, our technique is relatively safe for patients who have previously undergone multiple surgeries and decreases the risk of postoperative complications due to the shorter exposure time of the titanium plate during the second surgery. J. Med. Invest. 72 : 185-188, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"185-188"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040461","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effects of the COVID-19 Pandemic on the Lifestyle and Physical Activity of School-aged Children : Survey of Students at Japanese Language Supplementary School in the United States. COVID-19大流行对学龄儿童生活方式和身体活动的影响：对美国日语补习学校学生的调查

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.117

Fusako Imoto, Kikuko Okuda, Mieko Fujikawa, Tetsuya Tanioka

{"title":"Effects of the COVID-19 Pandemic on the Lifestyle and Physical Activity of School-aged Children : Survey of Students at Japanese Language Supplementary School in the United States.","authors":"Fusako Imoto, Kikuko Okuda, Mieko Fujikawa, Tetsuya Tanioka","doi":"10.2152/jmi.72.117","DOIUrl":"https://doi.org/10.2152/jmi.72.117","url":null,"abstract":"Coronavirus disease 2019 (COVID-19) and associated lockdowns affected many people regardless of location, age, or gender. This study aimed to focus on school-aged children studying at a Japanese Language Supplementary School (JLSS) in the southwestern region of the United States and assessed the impact of COVID-19 on their lifestyle and physical activity (PA). An online-based cross-sectional survey was administered to students (age range : 6-18) enrolled in a JLSS as of June 11, 2021. Data were collected from 151 students. The questionnaire consisted of lifestyle and PA questions. A paired and Student t-test was used to test the differences in changes before COVID-19 and during COVID-19 among children. Chi-square tests were used for comparisons with descriptive analyses of frequencies. Level of statistical significance was set at p <.05. Screen time was significantly longer on weekdays (t = 8.71, p<.001) and weekends (t = 5.94, p < .001) than before COVID-19. The number of children who went to bed after 10 pm was significantly higher (χ2 = 4.06, p < 0.05) than before the new coronavirus infection. The frequency of PA per week was significantly higher (χ2 = 4.01, p < 0.05) in the group using digital devices. Findings suggested that the use of digital devices for PA can enhance PA frequency in JLSS students. J. Med. Invest. 72 : 117-123, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"117-123"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040938","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effectiveness of Combined Vitamin D and Iron Supplementation on Iron Status in Children with Iron Deficiency Anemia: A Randomized Controlled Trial. 联合补充维生素D和铁对缺铁性贫血儿童铁状态的影响：一项随机对照试验。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.337

Nadirah Rasyid Ridha, Bahrul Fikri, Irwan, Conny Tanjung, Andi Alfian Zainuddin, Destya Maulani, Sri Hardiyanti Putri

{"title":"Effectiveness of Combined Vitamin D and Iron Supplementation on Iron Status in Children with Iron Deficiency Anemia: A Randomized Controlled Trial.","authors":"Nadirah Rasyid Ridha, Bahrul Fikri, Irwan, Conny Tanjung, Andi Alfian Zainuddin, Destya Maulani, Sri Hardiyanti Putri","doi":"10.2152/jmi.72.337","DOIUrl":"10.2152/jmi.72.337","url":null,"abstract":"Introduction: Vitamin D may reduce inflammation by affecting cytokine production, potentially alleviating chronic anemia. Iron deficiency can impair vitamin D absorption, yet the interaction between these deficiencies remains unclear. This study aimed to evaluate the effectiveness of combined vitamin D and iron supplementation in treating iron deficiency anemia (IDA) in children.Methods: An open-label, randomized controlled trial was conducted at four outpatient clinics and Dr. Wahidin Sudirohusodo Hospital, Makassar, Indonesia. Of 250 assessed patients, 67 met the inclusion criteria. Participants were randomized into two groups:Group A received iron supplementation (3 mg/kg BW/day), while Group B received iron combined with vitamin D (400 IU). Treatment lasted 4 weeks, and iron status was evaluated pre- and post-treatment.Results: No significant changes were observed in complete blood count, serum iron, and ferritin levels after 4 weeks in either group (p>0.05). However, the mean change in serum ferritin levels was significantly greater in the combined group (p=0.039).Conclusion: Both iron alone and iron with vitamin D improved hematological parameters in children with iron deficiency anemia. Combined iron and vitamin D therapy showed a significant ferritin increase, suggesting that adding vitamin D may support better iron storage. J. Med. Invest. 72 : 337-342, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"337-342"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439621","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Coping with Menopausal Symptoms among Japanese Teachers : Associations with Symptom Severity and Knowledge. 日本教师应对更年期症状：与症状严重程度和知识的关系

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.85

Yukie Matsuura, Toshiyuki Yasui

{"title":"Coping with Menopausal Symptoms among Japanese Teachers : Associations with Symptom Severity and Knowledge.","authors":"Yukie Matsuura, Toshiyuki Yasui","doi":"10.2152/jmi.72.85","DOIUrl":"10.2152/jmi.72.85","url":null,"abstract":"Menopausal symptoms can significantly affect the performance of working women. The association between knowledge of symptoms, educational level and better coping with the symptoms has been found. However, no study has been performed about coping with menopausal symptoms among school teachers who have higher educational background in Japan. This cross-sectional study explored coping strategies used by female teachers experiencing menopausal symptoms and the factors influencing their healthcare-seeking behaviors. Data were collected via a self-administered questionnaire between December 5, 2022 and February 28, 2023. Participants included 278 female teachers aged 45-60 years working in public elementary and junior high schools, of whom 156 (56.1%) reported menopausal symptoms. More than 80% of those with symptoms used at least one coping strategy : gathering information (68.6%), self-coping (60.9%), seeking advice (57.1%), and medical consultation (26.3%). Higher somatic menopausal symptom scores were associated with seeking medical consultation or advice. A significant correlation was observed between symptom severity and number of coping strategies used. Additionally, prior knowledge of menopause significantly increased the likelihood of information gathering and self-coping. Our findings underscore the need for support systems that help teachers cope with menopausal symptoms effectively, such as improving access to care and providing educational opportunities about menopause. J. Med. Invest. 72 : 85-92, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"85-92"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Congenital hypofibrinogenemia with a novel mutation BβCys76Phe. 先天性低纤维蛋白原血症伴新突变BβCys76Phe。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.182

Motoki Sugasaki, Shingen Nakamura, Shinpei Arai, Keisuke Teramoto, Minami Urushihara, Yusuke Inoue, Takayuki Nakao, Yasuhiko Nishioka, Masataka Sata

引用次数: 0

Effects of vitamin D on muscle mass and function in high school athletes. 维生素D对高中运动员肌肉质量和功能的影响。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.167

Hiroaki Nakajima, Yasushi Matsuura, Yasuhito Takeuchi, Rie Tsutsumi, Ayuka Kawakami, Mizusa Hyoudou, Kazuhiro Nomura, Hiroshi Sakaue, Teruhiro Morishita, Eiji Takeda

{"title":"Effects of vitamin D on muscle mass and function in high school athletes.","authors":"Hiroaki Nakajima, Yasushi Matsuura, Yasuhito Takeuchi, Rie Tsutsumi, Ayuka Kawakami, Mizusa Hyoudou, Kazuhiro Nomura, Hiroshi Sakaue, Teruhiro Morishita, Eiji Takeda","doi":"10.2152/jmi.72.167","DOIUrl":"https://doi.org/10.2152/jmi.72.167","url":null,"abstract":"Nutrition and exercise have effects on the body. The aim of the present study was to assess vitamin D status (serum 25-hydroxyvitamin D [25(OH)D] levels) and investigate its associations with muscle mass and function, as well as the effects of vitamin D supplementation on muscle function in high school athletes. Twenty-one high-school athlete students (6 males and 15 females) participated in this study. The serum 25(OH)D levels of 15 athletes (71.4%) with vitamin D insufficiency (VDI)/vitamin D deficiency (VDD) were and those of six athletes (28.6%) with vitamin D sufficiency (VDS) were 24.2 (22.3-27.0) ng/mL and 35.8 (33.0-38.9) ng/mL, respectively. Serum 25(OH)D concentration was significantly associated with total power in the male, female, and total athlete groups. Daily 1,000 IU vitamin D supplementation for 6 months increased serum vitamin D levels from 27.0 (22.9-32.1) ng/mL to 37.9 (28.9-40.9) ng/mL and improved muscle function in the total athlete group. Our findings suggest that daily 1,000 IU vitamin D supplementation should be recommended to optimize maximal aerobic power in high school athletes. J. Med. Invest. 72 : 167-171, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"167-171"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144001330","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0