JOURNAL OF MEDICAL INVESTIGATION最新文献_第7页

Prognostic performance of psoas muscle density in elderly patients undergoing curative surgery for gastric cancer. 高龄胃癌根治性手术患者腰肌密度对预后的影响。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.396

Masayuki Urabe, Mami Suzuki, Takahiro Fukai, Yui Hasegawa, Emi Terai, Yoshitaka Kiya, Goki Morizono, Masaya Hiyoshi, Toshiyuki Watanabe, Yojiro Hashiguchi

{"title":"Prognostic performance of psoas muscle density in elderly patients undergoing curative surgery for gastric cancer.","authors":"Masayuki Urabe, Mami Suzuki, Takahiro Fukai, Yui Hasegawa, Emi Terai, Yoshitaka Kiya, Goki Morizono, Masaya Hiyoshi, Toshiyuki Watanabe, Yojiro Hashiguchi","doi":"10.2152/jmi.72.396","DOIUrl":"https://doi.org/10.2152/jmi.72.396","url":null,"abstract":"Background: The proportion of elderly patients within the gastric cancer (GC)-affected population has been increasing. Accordingly, there is a pressing need for reliable methods to stratify surgical risk in geriatric GC cases. Psoas muscle density (PMD), a parameter indicative of sarcopenia, is readily assessable using standard radiological techniques and has been recognized as a prognostic marker in various malignancies. However, its clinical significance in GC, particularly among elderly patients, remains inadequately defined.Methods: We retrospectively reviewed 110 patients aged ≥75 years who underwent R0 gastrectomy for GC. The prognostic value of preoperative PMD, along with other nutritional indices, was assessed using Cox proportional hazards models.Results: Lower PMD was significantly associated with diffuse-type histology and higher incidence of postoperative complications. On univariate Cox regression analysis, PMD was significantly associated with overall survival. Multivariate analysis confirmed PMD as an independent predictor of overall survival (hazard ratio:0.57;95% confidence interval:0.35-0.91 per 10-Hounsfield unit increase), along with other nutritional parameters.Conclusion: Preoperative PMD was significantly associated with postoperative morbidity and independently predicted overall survival in elderly GC patients. Incorporating PMD assessment into preoperative evaluation may enhance risk stratification and guide perioperative management in this vulnerable population. J. Med. Invest. 72 : 396-400, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"396-400"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439654","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wavelength-dependent differences in survival of Cladosporium sphaerospermum exposed to ultraviolet light. 紫外光照射下球孢枝孢存活的波长依赖性差异。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.260

Michiyo Yamashita, Mutsumi Aihara, Yushi Onoda, Shiho Fukushima, Miharu Nagahashi, Toshihiko Aizawa, Shigeharu Yamauchi, Yasuo Fujikawa, Tomotake Tanaka, Yasuko Kadomura-Ishikawa, Kai Ishida, Mina Matsubara, Takashi Uebanso, Kazuaki Mawatari, Akira Takahashi

{"title":"Wavelength-dependent differences in survival of Cladosporium sphaerospermum exposed to ultraviolet light.","authors":"Michiyo Yamashita, Mutsumi Aihara, Yushi Onoda, Shiho Fukushima, Miharu Nagahashi, Toshihiko Aizawa, Shigeharu Yamauchi, Yasuo Fujikawa, Tomotake Tanaka, Yasuko Kadomura-Ishikawa, Kai Ishida, Mina Matsubara, Takashi Uebanso, Kazuaki Mawatari, Akira Takahashi","doi":"10.2152/jmi.72.260","DOIUrl":"https://doi.org/10.2152/jmi.72.260","url":null,"abstract":"Fungi are one of the main sources of microbial contamination in food and residential environments. There has been reported that fungi are more resistant to drugs than are viruses and bacteria, so efficient sterilization methods are still required. In this study, we examined the effectiveness of ultraviolet (UV) sterilization against mold by focusing on the wavelength and radiant flux dependence of UV. UVC or UVA irradiation inactivated the mold species Cladosporium sphaerospermum in a dose-dependent manner. The energy required to obtain the same inactivation differed significantly between UVC irradiation and UVA irradiation. UVC irradiation induced the formation of substantial amounts of cyclobutane pyrimidine dimers, whereas UVA irradiation did not show any significant difference from the unirradiated group. Furthermore, UVC irradiation induced morphological changes that could be observed by electron microscopy. On the other hand, UVA irradiation suppressed the growth rate. These results suggest that UVC and UVA irradiation have different effects on fungi. The results suggest that both UVC and UVA irradiation may help control fungal contamination. Since the effect of UV differs depending on the wavelength of irradiation, it will be necessary to understand the wavelength-specific effect and use it to control fungal contamination in the living environment. J. Med. Invest. 72 : 260-265, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"260-265"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The Kihon Checklist is a useful screening tool for predicting sarcopenia:A retrospective cross-sectional pilot study. 基洪检查表是一个有用的筛选工具，预测肌肉减少症：回顾性横断面试点研究。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.272

Hidenori Onishi, Tomoko Okamoto, Yuki Niida, Osamu Yamamura

{"title":"The Kihon Checklist is a useful screening tool for predicting sarcopenia:A retrospective cross-sectional pilot study.","authors":"Hidenori Onishi, Tomoko Okamoto, Yuki Niida, Osamu Yamamura","doi":"10.2152/jmi.72.272","DOIUrl":"https://doi.org/10.2152/jmi.72.272","url":null,"abstract":"Background: Early detection of sarcopenia is critical in countries with rapidly aging populations. In this study, we investigated the diagnostic accuracy of Kihon Checklist (KCL) in screening sarcopenia among older adults.Methods: This retrospective, cross-sectional study included 442 community-dwelling. A baseline questionnaire and KCL were administered to the participants, and their physical function and body composition were measured. Sarcopenia was defined according to Asian Working Group for Sarcopenia 2019 guidelines. Receiver operating characteristic (ROC) curve analysis was used to examine the diagnostic accuracy of KCL for sarcopenia. In addition, a novel approach using KCL along with patient age was considered.Results: Among the subjects (72.1% women;average age, 76.7 years), 34 (7.6%) had sarcopenia. The ROC-based diagnostic accuracy for sarcopenia was as follows:Area under the ROC curve (AUC) = 0.805 (95% confidence interval [CI] = 0.735-0.874) for KCL, 0.865 (95% CI = 0.811-0.920) for KCL 5 items model, 0.892 (95% CI = 0.851-0.934) for KCL plus age, and 0.922 (95% CI = 0.886-0.957) for KCL 5 items model plus age.Conclusion: KCL showed good diagnostic accuracy as a screening tool for predicting sarcopenia, suggesting utility in population-based approaches for sarcopenia detection. J. Med. Invest. 72 : 272-280, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"272-280"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439785","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of severe cardiogenic shock triggered by Legionella infection treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO). 静脉-动脉体外膜氧合治疗军团菌感染所致严重心源性休克1例。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.434

Kazuki Momota, Shotaro Otani, Konomi Moriwaki, Natsuki Bando, Koji Sato, Hiroki Sato, Yusuke Akimoto, Toshiyuki Nunomura, Yoshitoyo Ueno, Taiga Itagaki, Jun Oto

{"title":"A case of severe cardiogenic shock triggered by Legionella infection treated with veno-arterial extracorporeal membrane oxygenation (VA-ECMO).","authors":"Kazuki Momota, Shotaro Otani, Konomi Moriwaki, Natsuki Bando, Koji Sato, Hiroki Sato, Yusuke Akimoto, Toshiyuki Nunomura, Yoshitoyo Ueno, Taiga Itagaki, Jun Oto","doi":"10.2152/jmi.72.434","DOIUrl":"https://doi.org/10.2152/jmi.72.434","url":null,"abstract":"Background: Pneumonia caused by Legionella pneumophila and other Legionella spp. is associated with high hospitalization and mortality rates. We herein report a case of severe cardiogenic shock triggered by Legionella pneumonia that was successfully treated with venoarterial extracorporeal membrane oxygenation (VA-ECMO).Case presentation: A 59-year-old man was admitted to the emergency department with a fever and consciousness disturbance. He was diagnosed with Legionella pneumonia based on urinary antigen test results. Despite receiving supplemental oxygen, the patient's oxygenation worsened, necessitating immediate tracheal intubation. Mechanical ventilation and vasopressor therapy were initiated;however, tachycardia due to atrial fibrillation, along with a reduced ejection fraction of only 15%, led to the development of cardiogenic shock. On day 1 in the intensive care unit (ICU), VA-ECMO and intra-aortic balloon pumping (IABP) were introduced. By day 3, his tachycardia and myocardial dysfunction had improved, leading to the withdrawal of VA-ECMO on day 4. His respiratory function improved and he was extubated on day 7. He was discharged from the ICU on day 9.Conclusions: VA-ECMO is a valuable treatment modality for refractory cardiogenic and septic shock. Considering the induction of VA-ECMO as a therapeutic option at an appropriate time is important in such cases. J. Med. Invest. 72 : 434-437, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"434-437"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439558","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Association of lipids in lipoprotein subfractions with liver fibrosis in a mouse model of metabolic dysfunction-associated steatohepatitis. 代谢功能障碍相关脂肪性肝炎小鼠模型中脂蛋白亚组分中的脂质与肝纤维化的关系

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.375

Honoka Nakahara, Mayuko Ichimura-Shimizu, Shotaro Tachibana, Orgil Jargalsaikhan, Cai Qinyi, Yuko Miyakami, Hirohisa Ogawa, Satoru Matsuda, Koichi Tsuneyama

{"title":"Association of lipids in lipoprotein subfractions with liver fibrosis in a mouse model of metabolic dysfunction-associated steatohepatitis.","authors":"Honoka Nakahara, Mayuko Ichimura-Shimizu, Shotaro Tachibana, Orgil Jargalsaikhan, Cai Qinyi, Yuko Miyakami, Hirohisa Ogawa, Satoru Matsuda, Koichi Tsuneyama","doi":"10.2152/jmi.72.375","DOIUrl":"https://doi.org/10.2152/jmi.72.375","url":null,"abstract":"Metabolic dysfunction-associated steatohepatitis (MASH) exhibits inflammation and fibrosis in addition to lipid accumulation in the liver, which may progress to cirrhosis and liver failure. This study investigated whether the serum lipoprotein subfraction reflects fibrosis severity in a MASH mouse model. Nine-week-old male A/J and C57BL6/J mice were fed a high-fat/cholesterol/cholate-based diet to induce fibrotic MASH. To generate fibrosis of varying severity, mice were fed two diets with different cholesterol concentrations (1.25% and 2.5%). After 9 weeks of feeding, serum cholesterol and triglyceride levels of each lipoprotein were comprehensively analyzed, including chylomicron, very-large low-density lipoprotein, low-density lipoprotein (LDL), and high-density lipoprotein (HDL), with 20 subclasses according to particle size. Serum levels of very-large HDL-cholesterol, very-small HDL-cholesterol, very-small HDL-triglycerides, and very-small LDL-cholesterol were significantly higher in the stage 2 fibrosis group than the stage 1 fibrosis group. Serum very-small LDL-cholesterol levels were correlated with histological severity of MASH, which reportedly increases with the progression of MASH in humans. In conclusion, the serum lipoprotein subfraction reflects liver fibrosis severity even in early phase, independent of the severity of other MASH lesions in MASH model mice. Fractionating HDL, which have been measured in clinical practice, may help establish noninvasive markers of liver fibrosis. J. Med. Invest. 72 : 375-384, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"375-384"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439610","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of Continuous Intake of Onion Powder on Oxidative Stress Biomarkers and Skeletal Muscle Maintenance in Elderly Bedridden Individuals:A Pilot Study. 持续摄入洋葱粉对老年卧床患者氧化应激生物标志物和骨骼肌维持的影响：一项初步研究

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.324

Rie Mukai, Akari Kondo-Kawai, Toshiyuki Nakamura, Yuki Noboritama, Airi Otsuka, Atsuko Sakai, Natsuo Yasui, Mikiko Inatsugi, Daisuke Doi, Takeshi Nikawa, Junji Terao

{"title":"Effect of Continuous Intake of Onion Powder on Oxidative Stress Biomarkers and Skeletal Muscle Maintenance in Elderly Bedridden Individuals:A Pilot Study.","authors":"Rie Mukai, Akari Kondo-Kawai, Toshiyuki Nakamura, Yuki Noboritama, Airi Otsuka, Atsuko Sakai, Natsuo Yasui, Mikiko Inatsugi, Daisuke Doi, Takeshi Nikawa, Junji Terao","doi":"10.2152/jmi.72.324","DOIUrl":"https://doi.org/10.2152/jmi.72.324","url":null,"abstract":"The number of bedridden elderly is substantially increasing in our aging society. Bedridden patients experience muscle atrophy due to prolonged inactivity. We are concerned about whether the antioxidative flavonoid quercetin can prevent disuse muscle atrophy in elderly people considering that oxidative stress plays a role in this condition. This study explored the links between quercetin intake, oxidative stress, and muscle preservation in bedridden individuals. Onion was selected and a dose of 5 g of onion powder, which contains 99.7 mg of quercetin aglycone equivalent, was given to patients who were bedridden for 30 days. Plasma quercetin concentration was significantly increased in the onion powder group, with regular intake of quercetin meals maintaining high plasma levels (n=9). Higher plasma quercetin levels were linked to lower plasma oxidized low-density lipoprotein (ox-LDL) and urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) content. No correlation was identified in the indexes of muscle maintenance (volume of the quadriceps femoris muscle) and the minimum necessary activities of daily living (ADL). In conclusion, our small-scale pilot study involving bedridden individuals did not demonstrate a positive effect of continuous quercetin intake on the prevention of muscle atrophy. However, efficient dietary quercetin consumption can mitigate the elevation of in vivo oxidative stress. J. Med. Invest. 72 : 324-329, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"324-329"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439645","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of positive-pressure ventilation before extubation on respiratory function:physiological evaluation under simulated extubation. 拔管前正压通气对呼吸功能的影响：模拟拔管下的生理评估。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.361

Takuya Takashima, Marina Okubo, Shotaro Otani, Masaki Terazawa, Konomi Moriwaki, Saki Saijo, Natsuki Bando, Kazuki Momota, Hiroki Sato, Yuki Nakano, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Taiga Itagaki, Jun Oto

{"title":"Effect of positive-pressure ventilation before extubation on respiratory function:physiological evaluation under simulated extubation.","authors":"Takuya Takashima, Marina Okubo, Shotaro Otani, Masaki Terazawa, Konomi Moriwaki, Saki Saijo, Natsuki Bando, Kazuki Momota, Hiroki Sato, Yuki Nakano, Toshiyuki Nunomura, Manabu Ishihara, Yoshitoyo Ueno, Taiga Itagaki, Jun Oto","doi":"10.2152/jmi.72.361","DOIUrl":"10.2152/jmi.72.361","url":null,"abstract":"Background: Positive-pressure ventilation (PPV) before extubation may improve oxygenation and reduce complications after extubation. However, no study has quantitatively evaluated the effects of extubation on breathing and lung volume.Methods: A crossover randomized study was performed on 16 patients who received mechanical ventilation and planned to undergo extubation in the intensive-care unit. We used the automatic tube compensation (ATC) mode to simulate extubation. We used electrical impedance tomography and an esophageal balloon catheter to evaluate the work of breathing and lung volume after simulated extubation. We compared the work of breathing and lung volume with and without PPV before simulated extubation.Result: There were no differences in the changes in end-expiratory lung impedance (-7.4 [-18.2-2.3] vs. -11.2 [-16.6-1.1] arbitrary units, p=0.53), anterior-to-posterior ventilation ratio (0.60 [0.49-0.74] vs. 0.60 [0.52-0.79], p=0.75), esophageal pressure swing (4.9 [2.1-8.7] vs. 5.4 [1.9-6.6] cmH2O, p=0.61), dynamic transpulmonary pressure (7.2 [6.7-9.9] vs. 7.6 [6.6-9.7] cmH2O, p=0.93), and pressure time product (2.4 [1.4-4.2] vs. 3.1 [1.0-4.3] cmH2O*s, p=0.84) with and without PPV before simulated extubation.Conclusion: PPV before extubation did not affect breathing work or lung volume after extubation. Therefore, it may delay extubation and increase patient stress. J. Med. Invest. 72 : 361-366, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"361-366"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439649","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Wellens' Syndrome with Positive T Wave in Lead aVR Suggesting Severe Three-Vessel Coronary Arterial Disease. aVR导联伴T波阳性的韦伦斯综合征提示严重的三支冠状动脉疾病。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.451

Kazuki Tezuka, Shusuke Yagi, Yutaka Kawabata, Hiroyuki Aibara, Ryo Bando, Tomonori Takahashi, Robert Zheng, Tomoko Takahashi, Tomomi Matsuura, Yoshihito Saijo, Muneyuki Kadaota, Tomoya Hara, Takayuki Ise, Koji Yamaguchi, Hirotsugu Yamada, Takeshi Soeki, Masataka Sata

引用次数: 0

A case of pyogenic granuloma recurrent with satellite lesions. 化脓性肉芽肿复发伴卫星性病变1例。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.440

Kazutoshi Murao, Azusa Muguruma, Yurino Sato, Emi Kunikata, Hiromi Shirai, Kazuhide Mineda, Yoshiro Abe, Ichiro Hashimoto, Yoshiaki Kubo

{"title":"A case of pyogenic granuloma recurrent with satellite lesions.","authors":"Kazutoshi Murao, Azusa Muguruma, Yurino Sato, Emi Kunikata, Hiromi Shirai, Kazuhide Mineda, Yoshiro Abe, Ichiro Hashimoto, Yoshiaki Kubo","doi":"10.2152/jmi.72.440","DOIUrl":"https://doi.org/10.2152/jmi.72.440","url":null,"abstract":"A 10-year-old Japanese female was referred to our hospital for a rapidly growing and easily bleeding nodule on her right temple. A physical examination revealed a red ulcerated nodule on her right temple. Our clinical diagnosis was pyogenic granuloma (PG), and cryotherapy was performed several times. However, this did not remove the tumor;therefore, we excised it under local anesthesia. A histopathological examination of the removed tumor showed vascular proliferations arranged in discrete lobules in the dermis. Based on these findings, we confirmed the diagnosis of PG. About 4 months after the surgery, small nodules gradually developed around the surgical scar. The patient returned to our hospital 1 year after the surgery. A physical examination showed multiple, small, red papules scattered around the surgical scar. Based on the clinical findings of this case, we made a diagnosis of the recurrence of PG with satellitosis (RPGS). The lesions disappeared after 6 months of topical steroid and liquid nitrogen therapy. RPGS is a rare phenomenon, but its diagnosis and management can be problematic. It is important for physicians to recognize this phenomenon and inform patients of the possibility of recurrence and the development of satellite lesions after PG is resected. J. Med. Invest. 72 : 440-442, August, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 3.4","pages":"440-442"},"PeriodicalIF":0.8,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145439561","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of the renin-angiotensin system in pediatric kidney diseases and neonatal development. 肾素-血管紧张素系统在儿童肾脏疾病和新生儿发育中的作用。

IF 0.8

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.241

Maki Urushihara

引用次数: 0