JOURNAL OF MEDICAL INVESTIGATION最新文献_第4页

Cardiac arrest as an unusual complication in transforaminal full-endoscopic spine surgery under local anesthesia:a case report. 局部麻醉下经椎间孔全内窥镜脊柱手术中的罕见并发症--心脏骤停：病例报告。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.314

Takahiro Ogawa, Masatoshi Morimoto, Fumitake Tezuka, Kazuta Yamashita, Kosuke Sugiura, Shutaro Fujimoto, Michael Castro, Junzo Fujitani, Koichi Sairyo

{"title":"Cardiac arrest as an unusual complication in transforaminal full-endoscopic spine surgery under local anesthesia:a case report.","authors":"Takahiro Ogawa, Masatoshi Morimoto, Fumitake Tezuka, Kazuta Yamashita, Kosuke Sugiura, Shutaro Fujimoto, Michael Castro, Junzo Fujitani, Koichi Sairyo","doi":"10.2152/jmi.71.314","DOIUrl":"10.2152/jmi.71.314","url":null,"abstract":"Background: Transforaminal full-endoscopic surgery can be performed under local anesthesia, which is safer than general anesthesia, especially in the elderly. However, emergencies can still occur under local anesthesia. We describe a case of cardiac arrest at the start of full-endoscopic spine surgery under local anesthesia.Case presentation: The patient was an 80-year-old woman with right lower leg pain caused by two-level lumbar spinal canal stenosis. Two-stage full-endoscopic spine surgery under local anesthesia was planned. The first surgery was completed uneventfully. However, during the second surgery, cardiac arrest occurred because of Mobitz type II atrioventricular block. Percutaneous pacing was started immediately, followed by insertion of a temporary pacemaker via the femoral artery as a life-saving measure. Four days later, a permanent pacemaker was implanted. One month later, the second-stage decompression was completed without complications.Conclusion: Elderly patients require careful intraoperative monitoring for emergencies during surgery under local anesthesia as under general anesthesia. J. Med. Invest. 71 : 314-319, August, 2024.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"71 3.4","pages":"314-319"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510223","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A histopathologically diagnosed case of hypoglycemic encephalopathy due to insulin overdose. 一例经组织病理学诊断的胰岛素过量引起的低血糖脑病。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.340

Hitomi Umemoto, Hideyuki Nushida, Asuka Ito, Hiromitsu Kurata, Itsuo Tokunaga, Hirofumi Iseki, Akiyoshi Nishimura

{"title":"A histopathologically diagnosed case of hypoglycemic encephalopathy due to insulin overdose.","authors":"Hitomi Umemoto, Hideyuki Nushida, Asuka Ito, Hiromitsu Kurata, Itsuo Tokunaga, Hirofumi Iseki, Akiyoshi Nishimura","doi":"10.2152/jmi.71.340","DOIUrl":"10.2152/jmi.71.340","url":null,"abstract":"A 70-year-old man presented with cardiopulmonary arrest. Previous medical history included orally medicated diabetes mellitus, hypertension, stroke, and depression. The family observed that the patient had been sleeping for approximately 10 h. He was brought to the hospital and pronounced dead. Postmortem blood examinations revealed a blood insulin level of 0.54 μU/mL, C-peptide level of 0.14 ng/mL, and blood glucose of 9 mg/dL. Autopsy revealed an injection scar with intradermal hemorrhage and a subcutaneous hemorrhage in the left abdomen measuring 0.2 cm in diameter. Histopathological analysis revealed hemorrhage and inflammatory cell infiltration in the scar. Furthermore, subcutaneous adipose tissue, perivascular area, and neurons stained positive for anti-insulin antibody. HE staining of the brain revealed mild edema, and anti-GFAP antibody revealed clasmatodendrosis with bead-like staining of astrocyte subdivisions in the cerebral gray matter. Postmortem blood glucose evaluation is difficult because blood glucose levels are not stable and blood insulin is degraded relatively quickly. However, the cause of death was determined to be hypoglycemic encephalopathy due to insulin overdose because insulin was detected in the skin at the injection site. Furthermore, immunohistochemical examination of the brain revealed findings that were consistent with hypoglycemic encephalopathy. Therefore, histological examination was useful for postmortem diagnosis. J. Med. Invest. 71 : 340-342, August, 2024.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"71 3.4","pages":"340-342"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510219","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Acute myeloid leukemia developed through myeloproliferative features during immunosuppressive therapy for juvenile idiopathic arthritis. 在对幼年特发性关节炎进行免疫抑制治疗期间，因骨髓增生性特征而发展成急性髓性白血病。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.335

Masahiro Oura, Ryohei Sumitani, Yusaku Maeda, Hikaru Yagi, Mamiko Takahashi, Takeshi Harada, Shiro Fujii, Hirokazu Miki, Taiki Hori, Jumpei Murai, Kumiko Kagawa, Masahiro Abe, Shingen Nakamura

引用次数: 0

Five Years of Follow-up after Posterior Cervical Fusion Surgery for Hirayama Disease:A Case Report. 平山症后路颈椎融合术后五年随访：病例报告。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.298

Kosuke Sugiura, Toshinori Sakai, Masatoshi Morimoto, Hiroaki Manabe, Fumitake Tezuka, Kazuta Yamashita, Koichi Sairyo

{"title":"Five Years of Follow-up after Posterior Cervical Fusion Surgery for Hirayama Disease:A Case Report.","authors":"Kosuke Sugiura, Toshinori Sakai, Masatoshi Morimoto, Hiroaki Manabe, Fumitake Tezuka, Kazuta Yamashita, Koichi Sairyo","doi":"10.2152/jmi.71.298","DOIUrl":"10.2152/jmi.71.298","url":null,"abstract":"Background: Hirayama disease (HD) is characterized by slow progression of muscle atrophy without sensory disturbance in a single upper extremity in adolescent boys. HD can be treated using both conservative measures and surgery. However, the optimal treatment remains controversial.Case presentation: We have encountered an 18-year-old man with HD who presented to us with a 2-year history of progressive muscle atrophy and weakness of the left upper extremity. He underwent posterior cervical fusion surgery in the extended position without decompression. As of 5 years postoperatively, there has been no deterioration of his muscular atrophy and weakness and his condition has mildly improved. He was able to return to daily life and work with no difficulty.Conclusions: Although cervical fusion surgery has several risks, including adjacent segment disease, posterior spinal fusion surgery without decompression in the short segment can be considered as a surgical option for HD. J. Med. Invest. 71 : 298-302, August, 2024.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"71 3.4","pages":"298-302"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510230","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Successful dilation using a Non-Slip Element Percutaneous Transluminal Angioplasty Scoring Balloon to treat in-stent restenosis of carotid artery stenting with inadequate dilation during balloon angioplasty:A case report. 使用非滑动元件经皮腔内血管成形术评分球囊成功扩张，治疗在球囊血管成形术中扩张不足的颈动脉支架内再狭窄：病例报告。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.303

Manabu Yamamoto, Shigeomi Yokoya, Takuma Kato, Hidesato Takezawa

{"title":"Successful dilation using a Non-Slip Element Percutaneous Transluminal Angioplasty Scoring Balloon to treat in-stent restenosis of carotid artery stenting with inadequate dilation during balloon angioplasty:A case report.","authors":"Manabu Yamamoto, Shigeomi Yokoya, Takuma Kato, Hidesato Takezawa","doi":"10.2152/jmi.71.303","DOIUrl":"10.2152/jmi.71.303","url":null,"abstract":"Background: Carotid artery stenting (CAS) is commonly performed to treat internal carotid artery (ICA) stenosis;however, it is associated with high recurrence rates. The treatment of in-stent restenosis (ISR) following CAS poses several challenges, and percutaneous transluminal angioplasty (PTA) is a possible treatment option. Scoring balloons used in the cardiovascular field can prevent slipping and plaque incisions during balloon expansion;however, their efficacy in treating cervical ICA ISR remains uncertain.Case description: An 81-year-old man underwent CAS for carotid artery stenosis and subsequently developed ISR. Initial PTA with a noncompliant balloon failed to achieve sufficient dilation. However, the employment of a non-slip-element (NSE) PTA scoring balloon for additional expansion resulted in successful dilation, indicating its effectiveness in treating cervical ICA ISR. The patient was discharged postoperatively without any new neurological deficits, although magnetic resonance imaging revealed new ischemic lesions.Conclusion: The NSE PTA balloon could be considered as a valuable and effective treatment option for ISR when conventional balloon catheters face challenges in achieving dilation, although potential risks such as debris embolization should be considered. J. Med. Invest. 71 : 303-305, August, 2024.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"71 3.4","pages":"303-305"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510269","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Schizophrenia and cognitive dysfunction. 精神分裂症和认知功能障碍。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.205

Tomoya Takeda, Hidehiro Umehara, Yui Matsumoto, Tomohiro Yoshida, Masahito Nakataki, Shusuke Numata

引用次数: 0

Practices and Challenges of Home Care Pressure Ulcer Management;Perception of Home-visit Nurses Who Have Completed the Specified Medical Acts Training. 家庭护理压疮管理的实践与挑战；已完成特定医疗行为培训的家访护士的看法。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.346

Ruriko Yamashita, Reiko Hisada, Miki Mori, Saori Nishino, Mitsunori Daibatake

{"title":"Practices and Challenges of Home Care Pressure Ulcer Management;Perception of Home-visit Nurses Who Have Completed the Specified Medical Acts Training.","authors":"Ruriko Yamashita, Reiko Hisada, Miki Mori, Saori Nishino, Mitsunori Daibatake","doi":"10.2152/jmi.71.346","DOIUrl":"https://doi.org/10.2152/jmi.71.346","url":null,"abstract":"Purpose of the study: This study aims to clarify practices and challenges on pressure ulcer management as perceived by home-visit nurses who have completed the specified medical acts training.Methods: We gathered 8 home-visit nurses who have completed the training in Japan. First-author conducted in-depth, semi-structured individual interviews, asking for their insights on home care pressure ulcer management.Findings: We found that the home-visit nurses conducted the following practices;[having understandings and empathy as a health care professional who engage with client's lives with developing/worsening pressure ulcer], [pressure ulcer care at its best within limited resources], [systematic advice and guidance to caregivers and other professionals], and [demonstration of nursing as the post-training nurse of the specified medical acts]. We also learn that the home-visit nurses were faced with following challenges:[difficulties in smoothly collaborating with multiple professionals from different organizations], [not reaching a high level of expertise or skill], [limitations under the long-term care and medical insurance systems] and [impact of COVID-19].Conclusion: Home-visit nurses who have completed the specified medical acts training provided the nurses worked toward raising community's awareness of the care by providing leaderships to those involved in health care teams and collaborating with other professionals. J. Med. Invest. 71 : 346-355, August, 2024.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"71 3.4","pages":"346-355"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142510252","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

The role of thymic epithelium in thymus development and age-related thymic involution. 胸腺上皮在胸腺发育和与年龄相关的胸腺萎缩中的作用。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.29

Sayumi Fujimori, Izumi Ohigashi

引用次数: 0

Low prognostic nutrition index as a prognostic biomarker in elderly patients with early gastric cancer after gastrectomy. 低预后营养指数是老年早期胃癌患者胃切除术后的预后生物标志物。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.113

Takamasa Takahashi, Yuji Kaneoka, Atsuyuki Maeda, Yuichi Takayama, Hiroki Aoyama, Takahiro Hosoi, Kazuaki Seita

{"title":"Low prognostic nutrition index as a prognostic biomarker in elderly patients with early gastric cancer after gastrectomy.","authors":"Takamasa Takahashi, Yuji Kaneoka, Atsuyuki Maeda, Yuichi Takayama, Hiroki Aoyama, Takahiro Hosoi, Kazuaki Seita","doi":"10.2152/jmi.71.113","DOIUrl":"https://doi.org/10.2152/jmi.71.113","url":null,"abstract":"Purpose Non-invasive biomarkers including systemic inflammatory or nutrition-based index including neutrophil to lymphocyte ratio (NLR), platelet to lymphocyte ratio (PLR) lymphocyte to monocyte ratio (LMR), and prognostic nutritional index (PNI) can be useful in determining treatment strategies for elderly patients with early gastric cancer (EGC). The aim of this study was to investigate the significance of these index for predicting the long-term survival of EGC patients aged 80 years over. Methods This study included 80 elderly EGC patients with pStageIA after gastrectomy. Optimal cutoff value for PNI, NLR, PLR and LMR were set by using receiver operating curve analysis. The long-term outcomes after gastrectomy were analyzed by univariate and multivariate Cox regression analyses. Results Cut-off value for PNI, NLR, PLR and LMR was set at 46.5, 2.8, 210 and 4.6, respectively. By univariate analyses, low PNI, high NLR, high PLR and low LMR were significantly associated with worse prognosis. By multivariate analysis, low PNI was confirmed as an independent prognostic factor after gastrectomy (HR 0.17 ; 95% CI 0.03-0.91 ; P = 0.04). 5-year overall survival rate of patients with low PNI (≤ 46.5) were 52.4%. Conclusion Low PNI might be useful biomarker to predict worse prognosis of elderly EGC patients after gastrectomy. J. Med. Invest. 71 : 113-120, February, 2024.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"71 1.2","pages":"113-120"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Pancreatoduodenectomy combined with intestinal de-rotation as a complete artery-first approach for inexperienced surgeons. 胰十二指肠切除术联合肠道去转位术是一种适合经验不足的外科医生的完全动脉先入法。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2024-01-01 DOI: 10.2152/jmi.71.75

Yuji Morine, Yu Saito, Shinichiro Yamada, Teraoku Hiroki, Tetsuya Ikemoto, Mitsuo Shimada

{"title":"Pancreatoduodenectomy combined with intestinal de-rotation as a complete artery-first approach for inexperienced surgeons.","authors":"Yuji Morine, Yu Saito, Shinichiro Yamada, Teraoku Hiroki, Tetsuya Ikemoto, Mitsuo Shimada","doi":"10.2152/jmi.71.75","DOIUrl":"https://doi.org/10.2152/jmi.71.75","url":null,"abstract":"Background: Recent technical advances have reduced the incidence of intraoperative complications associated with pancreatoduodenectomy (PD). We aimed to determine whether inexperienced surgeons (ISs) would be as successful as experienced surgeons (ESs) when performing the complete artery-first approach using the intestinal de-rotation method of PD.Methods: Seventy patients who underwent PD using the intestinal de-rotation method in Tokushima University Hospital were enrolled in the present study. Intra- and post-operative parameters were compared between patients operated on by ESs (n=20) or ISs (n=50).Results: The surgical procedure lasted longer in the IS group (ES : 402 }68 min vs. IS : 483 }51 min, p<0.0001), but the volume of blood loss was similar (p=0.7304). There was no mortality in either group, and the incidences of postoperative complications with a Clavien-Dindo grade of>III did not differ between the groups. Grade B postoperative pancreatic fistulae developed in 20.0% of patients in the ES group and 22.0% in the IS group (p=0.9569). Finally, the postoperative hospital stay of the IS group (32 }33 days) was equivarent to that of the ES group (33 }16 days) (p=0.9256).Conclusion: ISs were able to perform similarly successful PDs using the intestinal de-rotation method to ESs. J. Med. Invest. 71 : 75-81, February, 2024.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"71 1.2","pages":"75-81"},"PeriodicalIF":0.7,"publicationDate":"2024-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140913063","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0