JOURNAL OF MEDICAL INVESTIGATION最新文献_第3页

Focused extracorporeal shockwave therapy for bilateral fatigue fractures of the proximal phalanges in the great toes : A case report. 聚焦体外冲击波治疗双侧大趾近端指骨疲劳骨折1例。

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.207

Kenji Yokoyama, Tetsuya Matsuura, Joji Iwase, Koichi Sairyo

引用次数: 0

Nursing Students in an Urban Setting During the COVID-19 Pandemic : Investigating Stress, Stress Response, and Coping Patterns by Descriptive Analysis, Structural Equation Modeling, and Data Sonification. 2019冠状病毒病大流行期间城市环境中的护生：通过描述性分析、结构方程建模和数据超声调查压力、压力反应和应对模式。

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.102

Joannes Paulus Tolentino Hernandez, Ramkumarie Baliram, Sandy Carollo, Juliet Baidoo-Kanneh

{"title":"Nursing Students in an Urban Setting During the COVID-19 Pandemic : Investigating Stress, Stress Response, and Coping Patterns by Descriptive Analysis, Structural Equation Modeling, and Data Sonification.","authors":"Joannes Paulus Tolentino Hernandez, Ramkumarie Baliram, Sandy Carollo, Juliet Baidoo-Kanneh","doi":"10.2152/jmi.72.102","DOIUrl":"https://doi.org/10.2152/jmi.72.102","url":null,"abstract":"Background: The COVID-19 pandemic has significantly impacted nursing students in urban settings. Understanding stress and coping in this population is essential for developing effective interventions for future pandemics and post-pandemic nursing education.Aims: This study assesses the interactions between demographic variables and stress responses, demonstrating these relationships through data sonification.Methods: A cross-sectional analytical study was conducted at an urban nursing college, with 195 participants completing modified versions of the Perceived Stress Scale, Physio-Psycho-Social Response Scale, and Coping Behavior Inventory. Structural equation modeling and data sonification were employed for analysis.Results: Nursing students reported moderate stress from academic demands and clinical responsibilities, utilizing coping strategies such as problem-solving and optimism. Structural equation modeling indicated a significant negative relationship between coping skills and physio-psycho-social stress (β = -0.301, p < .0001) and a negative association between age and perceived stress (β = -0.160, p = 0.035). Data sonification revealed synchronization between perceived stress and stress responses, with coping efforts peaking slightly after stress levels.Discussion: While students employ effective coping strategies, targeted interventions are needed to enhance stress management, especially for younger students.Conclusion: Stress and coping among nursing students in urban settings are complex, with data sonification providing deeper insights. J. Med. Invest. 72 : 102-116, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"102-116"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144056202","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Anesthesia management using ROP-1680 AsisTIVA : a case report. ROP-1680 AsisTIVA麻醉管理1例报告。

IF 0.7

JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.211

Ryosuke Kawanishi, Hiroki Yonezawa, Takamune Minote, Nami Kakuta, Katsuya Tanaka

引用次数: 0

Resuscitated patient after simultaneous intravascular thrombolytic therapy for massive pulmonary embolism and embolization of an injured hepatic artery : a case report. 同时血管内溶栓治疗大面积肺栓塞和损伤肝动脉栓塞后复苏的患者：1例报告。

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.177

Yuki Izawa-Ishizawa, Shizuo Ikeyama, Akiko Miyatake, Shiho Masuda, Michiko Tobiume, Yoshihiko Miyamoto, Yoh Nakai, Kazuo Yoshioka, Takashige Taoka

引用次数: 0

Melanoma antigen is a vaccine candidate against Meth A sarcoma. 黑色素瘤抗原是一种针对甲胺类肉瘤的候选疫苗。

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.161

Akiko Nakamoto, Haruka Ohashi, Yuko Tanaka, Mako Yamamoto, Mariko Nakamoto, Emi Shuto, Tohru Sakai

{"title":"Melanoma antigen is a vaccine candidate against Meth A sarcoma.","authors":"Akiko Nakamoto, Haruka Ohashi, Yuko Tanaka, Mako Yamamoto, Mariko Nakamoto, Emi Shuto, Tohru Sakai","doi":"10.2152/jmi.72.161","DOIUrl":"https://doi.org/10.2152/jmi.72.161","url":null,"abstract":"Sarcoma Meth A is widely used in the field of immunology and oncology study. We found that a mutant cell line, Meth A (mMeth A), was rejected in an in vivo subcutaneous challenge in BALB / c mice. mMeth A cells were not rejected in athymic BALB / c-nu / nu mice and CD8+ cell-depleted BALB / c mice, suggesting that CD8+ cells are required for rejection of mMeth A cells. Microarray analysis showed that melanoma antigen (MAg) was one of the most elevated genes in mMeth A cells. Indeed, quantitative gene expression analysis showed that the expression level of MAg in mMeth A cells was one hundred-times higher than that in Meth A cells. We constructed two types of expression vector coding the MAg gene sequence corresponding to 788-1257 and 1611-2043 and immunized mice with these genes by intramuscular injection. Immunization of a plasmid expressing the Mag 788-1257 gene protected the mice from in vivo Meth A challenge as evaluated by tumor volume and survival rate. The results reveal that MAg is a potential vaccine candidate antigen against Meth A tumors. J. Med. Invest. 72 : 161-166, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"161-166"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Effect of leg length discrepancy on spinopelvic alignment and mobility in healthy volunteers using a shoe lift. 腿长差异对使用提鞋的健康志愿者脊柱骨盆对齐和活动的影响。

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.26

Yumiko Ojima, Nori Sato, Tomohiro Goto, Tsuyoshi Goto, Tetsuya Okahisa, Ken Tomonari, Shinsuke Katoh, Shinichi Maeno, Koichi Sairyo

{"title":"Effect of leg length discrepancy on spinopelvic alignment and mobility in healthy volunteers using a shoe lift.","authors":"Yumiko Ojima, Nori Sato, Tomohiro Goto, Tsuyoshi Goto, Tetsuya Okahisa, Ken Tomonari, Shinsuke Katoh, Shinichi Maeno, Koichi Sairyo","doi":"10.2152/jmi.72.26","DOIUrl":"https://doi.org/10.2152/jmi.72.26","url":null,"abstract":"Background: Leg length discrepancy (LLD) is a musculoskeletal condition in which leg length is asymmetric. LLD can adversely affect adjacent joints. A typical example is hip-spine syndrome. We aimed to investigate how LLD affects spinopelvic alignment and mobility, under conditions simulating LLD.Methods: Fifty healthy adults (31 women, 19 men ; mean age 37.1 ± 8.9 years) participated in this study. A shoe lift was applied under the left foot to simulate LLD of 1, 2, 3, and 4 cm. Spinopelvic alignment while standing upright and mobility in flexion, extension, and lateral bending were measured under conditions simulating LLD using a Spinal Mouse device.Results: Lumbar spine curvature in the frontal plane was significantly increased to the left as LLD increased. Sacral inclination angle in the frontal plane was significantly increased to the right by adding a lift. There was no significant difference in curvature of the thoracic spine in any parameters. Mobility of the lumbar spine during left lateral bending decreased as LLD increased. Inclination between T1 and S1 in the frontal plane when bending to the left decreased with increasing LLD.Conclusion: Simulating LLD affects spinopelvic alignment and mobility in the frontal plane, but not significantly in sagittal plane. J. Med. Invest. 72 : 26-33, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"26-33"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"143990485","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

A case of delayed gastric conduit emptying after subtotal esophagectomy with simultaneous pulmonary resection. 食管次全切除术并发肺切除术后胃导管延迟排空1例。

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.189

Satoshi Fujiwara, Masakazu Goto, Seiya Inoue, Hiroyuki Sumitomo, Fuyumi Izaki, Taihei Takeuchi, Tomohiro Inui, Shinichi Sakamoto, Mariko Misaki, Naoya Kawakita, Takahiro Yoshida, Hiroaki Toba, Hiromitsu Takizawa

{"title":"A case of delayed gastric conduit emptying after subtotal esophagectomy with simultaneous pulmonary resection.","authors":"Satoshi Fujiwara, Masakazu Goto, Seiya Inoue, Hiroyuki Sumitomo, Fuyumi Izaki, Taihei Takeuchi, Tomohiro Inui, Shinichi Sakamoto, Mariko Misaki, Naoya Kawakita, Takahiro Yoshida, Hiroaki Toba, Hiromitsu Takizawa","doi":"10.2152/jmi.72.189","DOIUrl":"https://doi.org/10.2152/jmi.72.189","url":null,"abstract":"We report a case of delayed gastric conduit emptying (DGCE) after surgery for esophageal cancer. A 67-year-old man who visited a hospital because of dysphagia and was referred for a diagnosis of esophageal cancer. Contrast-enhanced computed tomography (CT) showed wall thickening of the middle thoracic esophagus and an enlarged abdominal lymph nodes and a spiculated pulmonary shadow 25×20 mm in size in right lower lobe that was highly suspected as a primary lung cancer. Preoperative chemotherapy was introduced due to advanced esophageal cancer, both the esophageal tumor and the pulmonary lesion were found to be shrunk. Even after a detailed examination, the shadow in the right lower lobe of the lung could not be ruled out for malignancy, a simultaneous surgery was conducted. The patient underwent S10 segmentectomy followed by subtotal esophagectomy and the posterior mediastinal route reconstruction using a gastric conduit. Gastrografin radiography revealed stasis of the reconstructed gastric conduit on postoperative day (POD) 8. CT and upper gastrointestinal endoscopy showed that the gastric conduit was pulled into the right thoracic cavity caused by pulmonary resection and developed inflammatory changes, causing DGCE. The DGCE eventually improved with conservative treatment and the patient was discharged on POD 68. J. Med. Invest. 72 : 189-193, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"189-193"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144040902","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Analysis of 69 Hepatocellular Carcinoma Cases from the National Center for Pathology in Mongolia : A Comprehensive Study of Samples Collected Nationwide. 蒙古国家病理中心69例肝细胞癌病例分析：全国样本综合研究

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.47

Orgil Jargalsaikhan, Wenhua Shao, Mayuko Ichimura-Shimizu, Soichiro Ishimaru, Takaaki Koma, Masako Nomaguchi, Battogtokh Chimeddorj, Khongorzul Batchuluun, Ganzorig Batbaatar, Gankhuu Gankhuyag, Saruul Gerelchuluun, Minoru Irahara, Masashi Akaike, Koichi Tsuneyama

{"title":"Analysis of 69 Hepatocellular Carcinoma Cases from the National Center for Pathology in Mongolia : A Comprehensive Study of Samples Collected Nationwide.","authors":"Orgil Jargalsaikhan, Wenhua Shao, Mayuko Ichimura-Shimizu, Soichiro Ishimaru, Takaaki Koma, Masako Nomaguchi, Battogtokh Chimeddorj, Khongorzul Batchuluun, Ganzorig Batbaatar, Gankhuu Gankhuyag, Saruul Gerelchuluun, Minoru Irahara, Masashi Akaike, Koichi Tsuneyama","doi":"10.2152/jmi.72.47","DOIUrl":"https://doi.org/10.2152/jmi.72.47","url":null,"abstract":"The high rate of chronic hepatitis, including hepatitis B, C and D, in Mongolia creates a large health burden of advanced liver disease. This includes liver failure and the highest incidence rate of hepatocellular carcinoma (HCC) worldwide. In the present study, we histopathologically examined 69 recent cases of HCC from the Mongolian National Center for Pathology, which collects specimens from across the country. The background liver histology of HCC exhibited a bimodal distribution, with one peak corresponding to advanced liver fibrosis and another to mild liver fibrosis. The fibrosis severity negatively correlated with age. Additionally, the frequency of poorly differentiated tumors was significantly higher in the HCC with early stage of fibrosis. A comparison of the pathological characteristics of HCC in urban and rural areas showed that poorly differentiated tumors were highly prevalent in urban areas. The characteristics of HCC in Mongolia are different from those in other countries, suggesting that the causes of liver disease are not only related to viruses but also other factors that depend on the region. This study will provide insight into what research is needed next for liver cancer control in Mongolia. J. Med. Invest. 72 : 47-53, February, 2025.","PeriodicalId":46910,"journal":{"name":"JOURNAL OF MEDICAL INVESTIGATION","volume":"72 1.2","pages":"47-53"},"PeriodicalIF":0.7,"publicationDate":"2025-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"144053677","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}

引用次数: 0

Immune checkpoint inhibitor-associated paraneoplastic cerebellar degeneration in a case of extensive-stage small-cell lung cancer with pre-existing anti-SOX1 antibody. 存在抗sox1抗体的广泛期小细胞肺癌的免疫检查点抑制剂相关的副肿瘤小脑变性

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.172

Kaori Nii, Hirokazu Ogino, Hiroki Bando, Yuki Yamamoto, Koji Fujita, Hiroto Yoneda, Nobuhito Naito, Atsushi Mitsuhashi, Yutaka Morita, Yuki Tsukazaki, Yohei Yabuki, Ryohiko Ozaki, Seidai Sato, Masaki Hanibuchi, Yuishin Izumi, Yasuhiko Nishioka

引用次数: 0

Lipolysis-stimulated lipoprotein receptor is involved in fatty acid binding protein 4-mediated prostate cancer cell growth in bone. 脂溶刺激脂蛋白受体参与脂肪酸结合蛋白4介导的骨内前列腺癌细胞生长。

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JOURNAL OF MEDICAL INVESTIGATION Pub Date : 2025-01-01 DOI: 10.2152/jmi.72.34

Tetsuyuki Takahashi, Takaaki Tsunematsu, Hisanori Uehara

引用次数: 0